CN1263458A - Stable herbal dentifrice - Google Patents
Stable herbal dentifrice Download PDFInfo
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- CN1263458A CN1263458A CN99800583A CN99800583A CN1263458A CN 1263458 A CN1263458 A CN 1263458A CN 99800583 A CN99800583 A CN 99800583A CN 99800583 A CN99800583 A CN 99800583A CN 1263458 A CN1263458 A CN 1263458A
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- toothpaste
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- sodium bicarbonate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
A dentifrice gel comprising up to 60 % baking soda, up to 5 % natural ingredients and up to 2 % flavor in addition to other dentifrice ingredients.
Description
Background of the present invention
1. field of the present invention
The present invention relates to oral health products, specifically, relate to toothpaste, more specifically to the gel dentifrice that contains fluoride and sodium bicarbonate.The present invention also relates to make the method for toothpaste and the method for using toothpaste.
2. the description of relevant prior art
People are familiar with for a long time toothpaste, and come cleaning teeth and antiplaque with it.The preparation teachers often seek new method improvement toothpaste people's captivation are done by the oral cavity health therapy to encourage people.Except done improvement aspect fragrance, people are also doing various visual improvement aspect traditional white paste over several years.
The improvement the most noticeable that people are done aspect visual attraction is to introduce the toothpaste gel.This toothpaste provides a kind of transparent or semitransparent gel to replace opaque in the past paste, gives masses with intensive captivation, and encourages people all to do by oral cavity health every day.
Recently interested for consumers another content is to use increasing " natural " composition in various products (also comprising toothpaste usually).Therefore, nearest a kind of traditional toothpaste component----sodium bicarbonate that in toothpaste, has used as cleaning agent.
Yet sodium bicarbonate is its stability as a problem of one of toothpaste component.When combining with water, sodium bicarbonate also is a sodium bicarbonate, is easy to decompose.Thereby the shelf life of baking soda dentifrice is of short duration in making us and can't accepting.
The people's such as Delaney that on February 10th, 1976 authorized United States Patent (USP) the 3rd, 937, No. 804 (together with the United States Patent (USP) the 3rd of its similar patent mandate on March 9th, 1976,943, all transfer Colgate-Palmolive Company No. 240) be an example of baking soda dentifrice, the sodium bicarbonate at least about 20%, preferred 30% is mixed with water, polyhydric alcohol wetting agent, gellant or thickening agent and fluoride.Owing to have macroscopic crystalline bicarbonate particles in level and smooth, the successive substrate in addition, therefore this toothpaste has granular texture in appearance.Owing to by the formation bulky grain sodium bicarbonate being separated from water and stability being kept.
The Fitz that authorized on July 5th, 1994, the United States Patent (USP) of Jr. relate to for the 5th, 326, No. 554 and contain sodium bicarbonate and as the composition for oral cavity of stablizing the sodium carbonate of buffer agent.
The people's such as Winston that the people's such as Winston that on November 18th, 1986 authorized No. the 4th, 623,536, United States Patent (USP) and on January 26th, 1988 authorize United States Patent (USP) relates to a kind of toothpaste that contains at least 60% sodium bicarbonate for the 4th, No. 721.614.The granularity of at least 30% bicarbonate is less than 25 microns, and bicarbonate is a scouring material unique in the toothpaste.The basis that less granularity it is said the stability that is this toothpaste institute claim.Each patent of above-mentioned Delaney is noticeable, because of these patents are by the degassing that stops the toothpaste preparation before outgasing fully stability to be kept.Therefore, each patent of Delaney has been avoided the various unacceptable raising that taken place aspect pH.
The people's such as Winston that authorize July 24 nineteen ninety United States Patent (USP) relates to a kind of toothpaste gel that contains sodium bicarbonate for the 4th, 943, No. 429.This toothpaste comprises up to the sodium bicarbonate of about 60% (weight) and at least about wetting agent such as the glycerol or the sorbitol of 22% (weight).This slightly (＞about 149 microns) rank preferably surpasses 30% bicarbonate and be bicarbonate, because of can make the concentration of bicarbonate in translucent gels higher than coarse particles.
Described in No. the 5th, 456,902, the people's such as Williams that authorize in October 10 nineteen ninety-five United States Patent (USP), sodium bicarbonate and peroxide toothpaste are provided to avoid occurring the problem of stable aspect with the design of being in charge of.
Sodium bicarbonate also can have good or bad influence to other the various compositions in the toothpaste.People's such as Winston United States Patent (USP) the 5th for example, 180, No. 576 (mandate on January 19th, 1993) and United States Patent (USP) the 5th, 318, No. 773 (mandate on June 7th, 1994) all relate to a kind ofly sneaks into toothpaste in the toothpaste with pyrophosphate (tartar inhibitor) and sodium bicarbonate.Sodium bicarbonate it is said to have synergism performance with combining of pyrophosphate, the feasible pyrophosphate that can adopt negligible amounts.Yet we find to transport two kinds of compositions all is independent solid in toothpaste, " saltouts " from pyrophosphate because of bicarbonate, has only pyrophosphate seldom to be dissolved in the toothpaste before use.
The people's such as Winston that authorize October 3 nineteen ninety-five United States Patent (USP) relates to zinc oxide and the compound action of sodium bicarbonate in toothpaste for the 5th, 455, No. 024.
Except sodium bicarbonate, people also are incorporated into other natural component in the toothpaste.The people's such as Hirose that authorized in 22nd as JIUYUE in 1992 United States Patent (USP) relates to a kind of oral care composition such as toothpaste the 5th, 149, No. 521.It has described a kind of compositions that comprises powdery granule, menthol and Herba Ocimi (Herba Ocimi Pilosi), Laurel, lavandula angustifolia or lactone.This compound action has obtained a kind of graininess in use and has felt the compositions that greatly reduced.
Use the example of a kind of toothpaste of various " natural " composition to see to be set forth in the nineteen ninety-five people's such as Nabi that authorized in 5th of December No. the 5th, 472,684, the United States Patent (USP).In this patent, according to its claim, thymol, acetaminol and optional a kind of sesquiterpene alcohols such as the combination of farnesol have anti-microbial property.This compositions adopts following various natural agents to carry out seasoning, as: Chamomile, myrrh gum, rhatany root, Australia tea tree oil, cineole, sage oil, Tulsi oil, Neem oil, Echinacea (Eichinacea) tincture, Herba Rosmarini Officinalis extracting solution, goldenseed extracting solution, maypop extracting solution, Rhizoma Curcumae Longae extracting solution, betel nut extracting solution, sunphenon tea extracting solution and Radix Taraxaci extracting solution.
The people's such as Cocherell that on March 14th, 1989 authorized United States Patent (USP) the 4th, relate to a kind of anhydrous toothpaste that contains Oleum Anisi Stellati, cloves oil, yellow Camphor tree, Herba Menthae, glycerol, corn starch, fluoride, sweetener, sodium lauryl sulphate, sodium bicarbonate and vegetable oil for 812, No. 306.
Containing the problem that the toothpaste gel of various natural components faces is the syneresis problem, and promptly liquid component is easy to emanate in gel.The high preparation of solids content as the toothpaste that contains sodium bicarbonate in this problem especially outstanding.
This research of seeking natural therapy is not limited only to toothpaste.United States Patent (USP) the 4th as the people such as Warren that authorized on June 2nd, 1987, the Semen Myristicae oil, Semen Myristicae extracting solution, bitter orange flower oil, oil of Rhizoma et radix valerianae, myristicin, elemecin or the elemicin that disclose use suction or transdermal release dosage for 670, No. 264 are with the nervous emotion of releiving.
The United States Patent (USP) the 5th of the Zeines that authorize January 3 nineteen ninety-five, relate to a kind of collutory that comprises Echinacea, canada yellow-root, Bloodroot canadensis, white oak (quercusalbe), grapefruit seed extracting solution, Aloe vera juice, water, plant glycerol and Oleum menthae for 378, No. 465.
The people's such as Vid é ki that on August 27th, 1991 authorized United States Patent (USP) relates to the compositions of a kind of prevention and treatment periodontal disease (parondonthopathy) for the 5th, 043, No. 153.Said composition comprises the aqueous solution of Herba Chelidonii, Herba Menthae, Flos Inulae, Herba thymi vulgaris, millfoil and optional Chamomile, Herba Meliloti officinalis leaf and Flos Caryophylli or arnica.
The United States Patent (USP) of the Noorlander that authorized on June 2nd, 1987 relates to a kind of allantion of comprising (Bellis perennis extracting solution) for the 4th, 670, No. 263 and the nontoxic antibacterial of ascorbic acid, chlorophyll or the carotene chosen wantonly.
Except the composition of sodium bicarbonate and other various " natural ", the makers-ups of toothpaste continue to seek various more effectively toothpaste components.The United States Patent (USP) of the Lukacovic that on November 26th, 1996 authorized relates to for the 5th, 578, No. 294 a kind of at the oral composition that does not have to contain under the situation of enzyme chelating agen and hydrophobic anion surfactant.Described chelating agen can be a betanin, and surfactant then is preferably the compositions of sarcosinate and tartrate.This compound action provides cleaning efficacy and can not make soft tissue that desequamation takes place.Added enzyme in No. the 5th, 320,831, the people's such as Majeti that authorize on June 14th, 1994 the United States Patent (USP), this patent relates to the oral composition that contains enzyme, surfactant, chelating agen and fluoride ion source.
Although people grow with each passing day to the interest in these fields, described technology still must be produced a kind of stable aqueous dentifrice gel that contains sodium bicarbonate and have other various natural components of intense clear performance.
Summary of the present invention
Therefore, it is a principal object of the present invention to provide a kind of contain sodium bicarbonate, stable, aqueous dentifrice.
Another target of the present invention provides a kind of other various toothpaste with natural component of intense clear performance that contain.
An advantage of the invention is that described toothpaste can be mixed with gel.
Another advantage of the present invention is that it can give happy aesthetic quality, thereby encourages people often to use this toothpaste.
Other target of the present invention and advantage part will be illustrated in the following description, and part is then apparent in this explanation, maybe can be familiar with by implementing the present invention.By various means and compositions, particularly in appending claims, point out those, people can be familiar with and get access to all types of target of the present invention and advantage.
In order to realize above-mentioned target and following purpose of the present invention, with broadly described such, the invention provides a kind of aqueous toothpaste that comprises the admixture of sodium bicarbonate and various natural components just as here embodied.
For further realizing above-mentioned each target and for purposes of the present invention, the present invention also provides the method for the toothpaste of the admixture that a kind of preparation contains water, sodium bicarbonate and various natural components.The description of preferred embodiment
Now will be in detail with reference to the present embodiment preferred of the present invention.
Usually be difficult to a kind of toothpaste very highly filled, particularly sodium bicarbonate of preparation or gel.This is because so high solid preparation is easy to take place syneresis and segregation.When mixing with the various natural components of liquid form such as various tincture and extracting solution, it is more serious that this problem will become.
In order to address this problem, the invention provides a kind of admixture that comprises sodium bicarbonate, various natural components, flavorant and other mixes the toothpaste component of stablizing the toothpaste gel to form.
One of composition among the present invention is that sodium bicarbonate is a sodium bicarbonate.Toothpaste of the present invention can comprise the sodium bicarbonate up to 60% (weight).Yet preferred sodium bicarbonate accounts for about 55% (weight) of about 35%-of toothpaste, about 50% (weight) of about 40%-more preferably.In the most preferred embodiment of the present invention, sodium bicarbonate accounts for about 45% (weight) of toothpaste.Though the granularity of sodium bicarbonate is not crucial for the present invention, the grain-size classification of preferred sodium bicarbonate based on following screening class: 0-2% (weight) be trapped on the 100# standard screen, 20-45% (weight) is trapped on the 200# standard screen and 60-100% (weight) is trapped on the 325# standard screen.
Except sodium bicarbonate, described toothpaste also comprises various natural components.Herein " natural " composition refer to those usually (but needn't) from through each kind of plant of minimum chemical modification or processing, extracting or deutero-composition.Many this compositions can be buied from the market, comprise (but being not limited thereto) various plant extraction liquids, from various herbaceous plant and the flower pressed liquor and the distillate of various materials.
A kind of compositions of preferred natural component sees Parodontax
In the board toothpaste, it comprises the chemical compound of Echinacea, Myrrha, Chamomile, rhatany and Salvia japonica Thunb..
Echinacea that is to say Folium Rudbeckiae Laciniatae juice or the extracting solution known to us, and is commercially available.It is described to dried rhizome of Echinacea pallida and root, and comprises inulin, sucrose, betanin and other various compositions.
Myrrha is described to various derived from Commiphora, and is the mixture of a kind of natural gum, volatile oil and bitter principle.It is to sell with the form of tincture (a kind of alcoholic solution of non-volatile matter) on market.
The inflorescence that Chamomile does from Anthemis nobilis.Its tincture is commercially available, and comprises bitterness glucoside, Chamomile sterol (anthesterol), anthemene and volatile oil.
Rhatany that is to say the Krameria known to us, is Krameria triandra dried root and other Krameria plant.It comprises Krameriatannic acid, and the form that can be used as a kind of tincture is buied from the market.
Salvia japonica Thunb. that is to say the Salvia known to us, is a kind of well-known flavoring agent.On sale on the market, its tincture is derived from the cured leaf of Salvia officinalis.It comprises volatile oil, resin, tannin and the bitter principle of 1-2.5%.
Though any natural composition, particularly sodium bicarbonate in gel is easy to emanate or the natural component of syneresis phenomenon all belongs in the category of the present invention the admixture of our preferred various natural components.In the preferred embodiment of the invention, the admixture of described natural component is Parodontax
The compositions of board toothpaste natural component (though also can comprise other various natural components).
In preferred embodiments, various natural components can account for high about 5% (weight) to toothpaste.In a more preferred embodiment, various natural components can account for about 4% (weight) of about 1%-of toothpaste.In preferred embodiment of the present invention, various natural components can account for about 4% (weight) of about 2%-of toothpaste, and in highly preferred embodiment of the present invention, various natural components can account for about 3.6% (weight) of toothpaste.In following examples, various natural components: Echinacea, Myrrha, Chamomile, Salvia japonica Thunb. and rhatany account for 3.596% (weight) of toothpaste preparation.Those skilled in the art will recognize that, in the definition of 3.596% described fully herein " about 3.6% ".
Except sodium bicarbonate and other various natural components, toothpaste also can contain other various compositions that are used for toothpaste, comprises gel dentifrice.
In toothpaste, can comprise fluoride source, as sodium fluoride, stannous fluoride or sodium monofluorophosphate.Fluoride source be usually less than toothpaste about 5%, more preferably less than about 2%, most preferably be lower than about 1%.
Toothpaste can comprise various surfactant and the detergents that help cleaning teeth.Common surfactant comprises various betanins, as cocamidopropyl betaine, sodium lauroyl sarcosine, LYSOLECITHIN SUNLECITHIN A and other detergent well known in the art and surfactant.Usually these surfactants use with detergent, and can account for about 5%, preferred about 3% (weight) of toothpaste.
Toothpaste of the present invention also can comprise various abrasives and abrasive cleaner.The example of this chemical compound comprises (but being not limited thereto) silica sol and amorphous silica.These chemical compounds can use separately, also can unite use, be generally toothpaste about 15% (weight) of about 5%-, be preferably about 12% (weight) of about 6%-, most preferably be about 10% (weight).
Toothpaste also can comprise wetting agent, as sorbitol solution and glycerol.Toothpaste can comprise toothpaste about 40% (weight) of about 10%-, be preferably about 35% (weight) of about 20%-, the wetting agent of about 27% (weight) more preferably.
Toothpaste also can contain binding agent such as HANSHENGJIAO, and sweetener such as saccharin sodium.Binding agent is usually less than about 1% (weight) of toothpaste, and the amount of sweetener is adjustable to the requirement that meets on the sense of taste.
An advantage of the invention is and quite a large amount of flavorants can be incorporated in the toothpaste.Though this flavorant can be above-mentioned various " natural " composition, the main purpose of this composition is that pleasant abnormal smells from the patient is given to toothpaste.Usually flavorant comprises various mint flavourings, as Herba Menthae Rotundifoliae and Herba Menthae.Yet the present invention is not limited to mint flavored toothpaste.Flavorant may be up to about 5% (weight) of toothpaste, though flavorant be preferably up to toothpaste preparation about 3% (weight), be more preferably up to about 2% (weight).
Toothpaste also can contain other known various compositions that are useful in the toothpaste, comprises (being not limited thereto) brightening agent, anticalculus agent and desensitization compounds.
Surprisingly, preparation prepared in accordance with the present invention seems very stable.Though the present invention does not want to be subject to any concrete theory of operation, seem the combination of various compositions and/or the processing of various compositions to make this product seem very stable physically.
Toothpaste of the present invention is to be prepared according to the method that is proposed among the embodiment 1 basically.With various water soluble salts, in water, mix as fluoride and sweetener.Add wetting agent and binding agent then.Add various natural components, abrasive cleaner, detergent and sodium bicarbonate again.Add flavorant oil, more detergent and other various natural components at last.
Though following each embodiment is used for illustrating features more of the present invention and advantage, they do not have the meaning of any limitation to the category of appending claims.
Embodiment 1
By 274 kg water are encased in the mixing channel 3000 kilograms of preparations (3,000Kg) in batches according to toothpaste of the present invention.Add 1.5 kilograms of saccharin sodium and 9.3 kilograms of sodium fluoride and be stirred to till the dissolving.Under the situation of continuous stirring, 300 kilograms of glycerol and 510 kilograms of sorbitol are joined in the groove.Slowly add 15 kilograms of HANSHENGJIAO, under high shear mixed about 30 minutes.18.7 kilograms of Myrrha tinctures, 18.7 kilograms of Chamomile tinctures and 28.5 kilograms of Echinaceas are slowly joined in the groove.Under the blended situation of high shear force, add 24 kilograms of silica sol, and then add 300 kilograms of amorphous silicas.Add sodium sarcosinate (30 kilograms), 700 kilograms of sodium bicarbonate, 6 kilograms of cocamidopropyl betaine, other 650 kilograms of sodium bicarbonate, 57.8 kilograms of Oleum menthae, 15 kilograms of LYSOLECITHIN SUNLECITHIN A, 4.38 kilograms of sage oils and 37.44 kilograms of rhatany tinctures.Whole product is fully mixed, and transfer is filled in the suitable pipe.The prescription that described toothpaste has in the table 1 to be proposed.
The preparation of a part of embodiment 1 is positioned over the freezing/fusion test of the column criterion of going forward side by side in 25 milliliters of dentifrice tubes.It the results are shown in the table 2.Sample carries out 4 months by a definite date stability test under 40 ℃, the results are shown in the table 3." NR " in the table 2 and 3 refers to there is not reading.The performance that " qualified " refers to be tested is fully in the designing requirement of product.For the globality of outward appearance and container, designing requirement does not have obvious defects.For Mang Saierse, designing requirement is 7.5R 2/4; 7.5R 6/6.
Embodiment 2 and 3
Adopt the method preparation that is proposed among the embodiment 1 to have the toothpaste of table 1 prescription.Partly these preparations are positioned in 25 milliliters of dentifrice tubes and carry out freezing/fusion test and stability test.The results are shown in the table 3.Embodiment 3 does not test the stability under 40 ℃.
| Table 1--toothpaste preparation | |||
| Composition | Embodiment 1 (weight %) | Embodiment 2 (weight %) | Embodiment 3 (weight %) |
| Water | ????9.118 | ????8.298 | ????13.218 |
| Sodium fluoride | ????0.31 | ????0.23 | ????0.31 |
| Saccharin sodium | ????0.05 | ????0.05 | ????0.05 |
| The Folium Rudbeckiae Laciniatae pressed liquor of stabilisation | ????0.954 | ????0.954 | ????0.954 |
| The Myrrha tincture | ????0.624 | ????0.624 | ????0.624 |
| The Chamomile tincture | ????0.624 | ????0.624 | ????0.624 |
| The rhatany tincture | ????1.248 | ????1.248 | ????1.248 |
| Sorbitol solution 70% | ????17 | ????17 | ????17 |
| Silica sol | ????0.8 | ????1.7 | ????1.7 |
| Amorphous silica | ????10 | ????10 | ????5 |
| Glycerol 96% | ????10 | ????10 | ????10 |
| HANSHENGJIAO | ????0.5 | ????0.5 | ????0.5 |
| Cocamidopropyl betaine | ????0.2 | ????0.2 | ????0.2 |
| Sodium lauroyl sarcosine | ????1 | ????1 | ????1 |
| LYSOLECITHIN SUNLECITHIN A | ????0.5 | ????0.5 | ????0.5 |
| Sodium bicarbonate | ????45 | ????45 | ????45 |
| Sage oil | ????0.146 | ????0.146 | ????0.146 |
| Oleum menthae | ????1.926 | ????1.926 | ????1.926 |
| Amount to | ????100.00 | ????100.00 | ????100.00 |
| The table 2--freezing/fusing data | ||||
| The performance of being tested | Time: 0 | 5 days | 9 days embodiment 3-10 days | 14 days |
| Outward appearance | 1: qualified | 1: qualified | 1: qualified | 1: qualified |
| 2: qualified | 2: qualified | 2: qualified | 2: qualified | |
| 3: qualified | 3: qualified | 3: qualified | 3: qualified | |
| Mang Saierse | 1: qualified | 1: qualified | 1: qualified | 1: qualified |
| 2: qualified | 2: qualified | 2: qualified | 2: qualified | |
| 3: qualified | 3: qualified | 3: qualified | 3: qualified | |
| pH | ??2：8.76 | ??2：8.72 | ??1：8.2 | ??1：8.2 |
| ??3：8.71 | ??3：8.40 | ??2：8.10 | ??2：8.29 | |
| ??1：1.56 | ??1：1.58 | ??3：8.59 | ??3：8.47 | |
| Viscosity (* 10 5) cps | ??2：1.76 | ??2：3.00 | ??1：1.72 | ??1：2.00 |
| ??3：1.40 | ??3：1.24 | ??2：3.80 | ??2：5.20 | |
| ??1：1358 | ??1：NR | ??3：2.40 | ??3：1.80 | |
| Ion fluoride (ppm) | ??2：1063 | ??2：NR | ??1：NR | ??1：1282 |
| ??2：NR | ??2：1022 | |||
| ??3：1501 | ??3：NR | ??3：NR | ??3：1433 | |
| Sodium bicarbonate weight % | ??1：46％ | ??1：NR | ??1：NR | ??1：45％ |
| ??2：46.4％ | ??2：NR | ??2：NR | ??2：46.1％ | |
| ??3：46.7％ | ??3：NR | ??3：NR | ??3：46.3％ | |
| Integral container | 1: qualified | ??1：NR | ??1：NR | 1: qualified |
| 2: qualified | 2: qualified | 2: qualified | 2: qualified | |
| 3: qualified | 3: qualified | 3: qualified | 3: qualified | |
| Table 3--stability test | ||||
| The performance of being tested | Time: 0 month | 1 month | 3 months | 4 months |
| Outward appearance | 1: qualified | 1: qualified | 1: qualified | 1: qualified |
| 2: qualified | ??2：NR | 2: qualified | 2: qualified | |
| Mang Saierse | 1: qualified | ??1：NR | ??1：NR | ??1：NR |
| 2: qualified | ??2：NR | 2: qualified | 2: qualified | |
| PH | ??1：8.3 | ??1：8.8 | ??1：8.4 | ??1：8.2 |
| ??2：8.76 | ??2：NR | ??2：8.18 | ??2：8.71 | |
| Viscosity (* 10 5)cps | ??1：1.56 | ??1：1.98 | ??1：2.44 | ??1：3.00 |
| ??2：1.76 | ??2：NR | ??2：6.30 | ??2：7.75 | |
| Ion fluoride (ppm) | ??1：1358 | ??1：1344 | ??1：1346 | ??1：1368 |
| ??2：1063 | ??2：NR | ??2：1000 | ??2：1042 | |
| Sodium bicarbonate weight % | ??1：46％ | ??1：46％ | ??1：47％ | ??1：48％ |
| ??2：46.4％ | ??2：NR | ??2：47.7％ | ??2：47％ | |
| Integral container | 1: qualified | 1: qualified | 1: qualified | 1: qualified |
| 2: qualified | ??2：NR | 2: qualified | 2: qualified | |
Purpose described above is the meaning that does not have limitation for embodiments more of the present invention are described.It will be apparent to those skilled in the art that, under the prerequisite that does not deviate from category of the present invention or spirit, in device of the present invention or method, can make various modifications and variations.
Claims (19)
1. oral cavity health preparation, it comprises: (a) sodium bicarbonate; (b) admixture of various natural components; (c) flavorant.
2. the oral cavity health preparation of claim 1, the admixture of wherein said various natural components comprises at least a composition that is selected from following material: Echinacea, Myrrha, Chamomile, rhatany and Salvia japonica Thunb..
3. toothpaste, it comprises: (a) sodium bicarbonate; (b) admixture of various natural components; (c) flavorant.
4. the toothpaste of claim 3, wherein sodium bicarbonate accounts for high about 60% (weight) to toothpaste.
5. the toothpaste of claim 4, wherein sodium bicarbonate accounts for about 55% (weight) of about 35%-of toothpaste.
6. the toothpaste of claim 5, wherein sodium bicarbonate accounts for about 50% (weight) of about 40%-of toothpaste.
7. the toothpaste of claim 6, wherein sodium bicarbonate accounts for about 45% (weight) of toothpaste.
8. the toothpaste of claim 3, the admixture of wherein said various natural components comprises at least a composition that is selected from following material: Echinacea, Myrrha, Chamomile, rhatany and Salvia japonica Thunb..
9. the toothpaste of claim 8, what the admixture of wherein said various natural components accounted for toothpaste is 5% (weight).
10. the toothpaste of claim 9, the admixture of wherein said various natural components accounts for about 4% (weight) of about 1%-of toothpaste.
11. the toothpaste of claim 10, the admixture of wherein said various natural components account for about 4% (weight) of about 2%-of toothpaste.
12. the toothpaste of claim 11, the admixture of wherein said various natural components account for about 3.6% (weight) of toothpaste.
13. the toothpaste of claim 3, it also comprises a kind of fluoride source.
14. the toothpaste of claim 13, it also comprises: at least a surfactant, at least a scouring abrasive, at least a wetting agent, at least a binding agent, at least a sweetener and water.
15. a toothpaste gel, it comprises: (a) up to the sodium bicarbonate of about 60% (weight); (b) up to the admixture of the various natural components of about 5% (weight); (c) up to the flavorant of about 2% (weight).
16. the toothpaste gel of claim 15, it also comprises: the fluoride source that (d) is lower than about 5% (weight); (e) up at least a surfactant of about 5% (weight); (f) at least a scouring abrasive of about 15% (weight) of about 5%-; (g) wetting agent of about 10%-about 40% (weight); (h) be lower than the binding agent of about 1% (weight).
17. a toothpaste gel, it comprises: (a) sodium bicarbonate of about 45% (weight); (b) the various natural component admixtures of about 3.6% (weight); (c) flavorant of about 5% (weight); (d) be lower than the fluoride source of about 1% (weight); (e) up at least a surfactant of about 3% (weight); (f) the scouring abrasive of about 10% (weight); (g) wetting agent of about 27% (weight); (h) be lower than the binding agent of 1% (weight); (i) be lower than the sweetener of about 1% (weight); (j) water.
18. a method for preparing toothpaste, it may further comprise the steps: (a) mix sweetener and fluoride source to form first kind of mixture in water; (b) at least a wetting agent is joined in described first kind of mixture; (c) at least a natural component, binding agent and at least a scouring abrasive are joined in described first kind of mixture to form second kind of mixture; (d) sodium bicarbonate, at least a surfactant, flavorant and at least a other natural component are mixed in described second kind of mixture to form toothpaste.
19. the method for claim 18, wherein said toothpaste are a kind of gel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3195198A | 1998-02-27 | 1998-02-27 | |
| US09/031,951 | 1998-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1263458A true CN1263458A (en) | 2000-08-16 |
Family
ID=21862275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN99800583A Pending CN1263458A (en) | 1998-02-27 | 1999-02-26 | Stable herbal dentifrice |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0996411A4 (en) |
| JP (1) | JP2002503257A (en) |
| KR (1) | KR20010020301A (en) |
| CN (1) | CN1263458A (en) |
| AU (1) | AU2883799A (en) |
| BR (1) | BR9904875A (en) |
| CA (1) | CA2288320A1 (en) |
| NZ (1) | NZ501197A (en) |
| WO (1) | WO1999043293A1 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899261B (en) * | 2006-07-26 | 2010-05-12 | 广州立白企业集团有限公司 | Baking soda toothpaste with salty taste |
| CN104771618A (en) * | 2015-03-19 | 2015-07-15 | 苏州谷力生物科技有限公司 | Fire-purging mouthwash and preparation method thereof |
| CN107137288A (en) * | 2017-06-16 | 2017-09-08 | 何家平 | A kind of Chinese herbal toothpaste |
| CN107260617A (en) * | 2017-08-07 | 2017-10-20 | 何家平 | A kind of soda ash toothpaste technique |
| CN107308096A (en) * | 2017-07-11 | 2017-11-03 | 何家平 | A kind of Chinese herbal toothpaste |
| CN108135825A (en) * | 2015-11-13 | 2018-06-08 | 宝洁公司 | Dentifrice composition with improved consumer experience |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020031481A1 (en) * | 1998-02-27 | 2002-03-14 | Jin Xu | Stable herbal dentrifice |
| US6485710B2 (en) * | 2000-12-27 | 2002-11-26 | Arthur Zuckerman | Appetite suppressant toothpaste |
| US6610277B2 (en) * | 2000-12-27 | 2003-08-26 | Arthur Zuckerman | Appetite suppressant toothpaste |
| JP4632553B2 (en) * | 2001-01-19 | 2011-02-16 | 日本ゼトック株式会社 | Oral composition |
| JP4611565B2 (en) * | 2001-03-30 | 2011-01-12 | 株式会社ナリス化粧品 | Fat synthesis accelerator and cosmetics |
| US6485711B1 (en) * | 2002-03-21 | 2002-11-26 | Michael J. Olmstead | Organic toothpaste containing saponin |
| KR100760970B1 (en) * | 2004-11-04 | 2007-10-04 | 김종철 | Tooth paste containing essential oil |
| IT201900006427A1 (en) * | 2019-04-29 | 2020-10-29 | Maria Teresa Marinelli | Anhydrous preparation for powdered toothpaste |
| WO2023191852A1 (en) * | 2022-03-28 | 2023-10-05 | Lubrizol Advanced Materials, Inc. | Stable dentifrice compositions with high sodium bicarbonate loading |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3937803A (en) * | 1972-10-04 | 1976-02-10 | Colgate-Palmolive Company | Flavored dental creams |
| US3943240A (en) * | 1973-08-20 | 1976-03-09 | Colgate-Palmolive Company | Toothpaste |
| CA1043264A (en) * | 1975-03-25 | 1978-11-28 | Martin Cordon | Dentifrices |
| US4647451A (en) * | 1984-05-11 | 1987-03-03 | Colgate-Palmolive Company | Anhydrous dentifrice |
| US5256401A (en) * | 1987-01-30 | 1993-10-26 | Colgate-Palmolive Company | Antibacterial antiplaque mouthwash composition |
| US5472684A (en) * | 1993-06-02 | 1995-12-05 | Colgate Palmolive Company | Oral compositions for plaque and gingivitis |
-
1999
- 1999-02-26 CN CN99800583A patent/CN1263458A/en active Pending
- 1999-02-26 CA CA002288320A patent/CA2288320A1/en not_active Abandoned
- 1999-02-26 NZ NZ501197A patent/NZ501197A/en unknown
- 1999-02-26 WO PCT/US1999/004387 patent/WO1999043293A1/en not_active Application Discontinuation
- 1999-02-26 KR KR1019997009905A patent/KR20010020301A/en not_active Application Discontinuation
- 1999-02-26 JP JP54396499A patent/JP2002503257A/en active Pending
- 1999-02-26 AU AU28837/99A patent/AU2883799A/en not_active Abandoned
- 1999-02-26 EP EP99909685A patent/EP0996411A4/en not_active Withdrawn
- 1999-02-26 BR BR9904875-2A patent/BR9904875A/en not_active IP Right Cessation
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899261B (en) * | 2006-07-26 | 2010-05-12 | 广州立白企业集团有限公司 | Baking soda toothpaste with salty taste |
| CN104771618A (en) * | 2015-03-19 | 2015-07-15 | 苏州谷力生物科技有限公司 | Fire-purging mouthwash and preparation method thereof |
| CN108135825A (en) * | 2015-11-13 | 2018-06-08 | 宝洁公司 | Dentifrice composition with improved consumer experience |
| CN107137288A (en) * | 2017-06-16 | 2017-09-08 | 何家平 | A kind of Chinese herbal toothpaste |
| CN107308096A (en) * | 2017-07-11 | 2017-11-03 | 何家平 | A kind of Chinese herbal toothpaste |
| CN107260617A (en) * | 2017-08-07 | 2017-10-20 | 何家平 | A kind of soda ash toothpaste technique |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2883799A (en) | 1999-09-15 |
| NZ501197A (en) | 2000-09-29 |
| EP0996411A1 (en) | 2000-05-03 |
| EP0996411A4 (en) | 2001-05-09 |
| BR9904875A (en) | 2001-10-16 |
| KR20010020301A (en) | 2001-03-15 |
| CA2288320A1 (en) | 1999-09-02 |
| JP2002503257A (en) | 2002-01-29 |
| WO1999043293A1 (en) | 1999-09-02 |
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