CN1255181C - Preparation of medicinal composition for nourishing - Google Patents
Preparation of medicinal composition for nourishing Download PDFInfo
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- CN1255181C CN1255181C CNB2004100123474A CN200410012347A CN1255181C CN 1255181 C CN1255181 C CN 1255181C CN B2004100123474 A CNB2004100123474 A CN B2004100123474A CN 200410012347 A CN200410012347 A CN 200410012347A CN 1255181 C CN1255181 C CN 1255181C
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Abstract
The present invention uses the theory of supporting healthy energy and eliminating evil in Chinese medicine to provide a medicine composition for improving body immune function, strengthening the spleen and invigorating the kidney, thereby achieving the purposes of solving current problems and eliminating root causes The medicine composition is prepared from the components of the following proportion by weight: 120 to 360 portions of milkvetch root, 100 to 300 portions of glossy privet fruit, 30 to 95 portions of ginseng, 30 to 95 portions of ganoderma, 65 to 195 portions of zedoary, 30 to 90 portions of sauted white atractylodes rhizome, 65 to 195 portions of spreading hedyotis herb, 65 to 195 portions of barbed skullcap herb, 120 to 360 portions of fiveleaf gynostemma herb, 30 to 95 portions of tuckahoe, 15 to 45 portions of chicken gizzard-membrane, 65 to 195 portions of indian mockstrawberry herb, 65 to 195 portions of bittersweet herb, 65 to 195 portions of artemisiae scopariae, 65 to 195 portions of paniculate swallowwort root and 10 to 30 portions of ground beetle. The pharmacological test research of a pharmacological room of a tumour academy in a Chinese medical science college shows that the medicine composition capsule of the present invention has obvious inhibiting effect on the growth of zoograft tumour of a mouse S180, the solid tumor of mouse liver cancer HAC, and mouse Lewis lung cancer, has obvious improving effect on the immune function of a normal mouse and a tumor-bearing mouse, and has the function of increasing white cells.
Description
Technical field
The present invention relates to a kind of foster positive removing food stagnancy drug combination preparation and preparation method of human body immunity improving function, belong to the Chinese herbal and crude drugs preparations technical field, mainly be applicable to auxiliary treatment asthenia of both the spleen and kidney, the interior resistance type primary hepatocarcinoma of stasis of blood poison clinically, diseases such as distension and fullness in the abdomen, appetite stimulator, Mental fatigue power lack, soreness of the waist and knees, twinge tenderness, the red just pool of urinating.
Background technology
" deficient " category of diseases genus motherland medical science such as emaciated physique, fatigue and asthenia, distension and fullness in the abdomen due to the combined symptoms in the deficiency of spleen and stomach such as tumor, hepatitis, liver cirrhosis, stasis of blood poison.At present, the Chinese medicine preparation of treatment immunocompromised, as Radix codonopsis pilosulae's soft extract (invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting), Polysaccharide-peptide capsule (nourishing the essence and strengthening QI, invigorating spleen and nourishing heart), ten flavor body-strengthening granules (benefiting vital QI and blood, warming YANG and strengthening the spleen), SHENQI FUZHENG ZHUSHEYE (QI invigorating is set upright), ginseng one capsule (element culturing fixed folder, benefiting vital QI and blood) etc., they are partial to mend more, and are too unilateral.
Summary of the invention
The present invention provides a kind of with the human body immunity improving function with traditional Chinese medical science strengthening vital QI to eliminate pathogenic factors theory, the foster positive removing food stagnancy drug combination preparation of strengthening spleen, tonifying kidney, it is deficiency of spleen and stomach that the treatment theory is based on diseases such as emaciated physique that immunocompromised disease occurs, fatigue and asthenia, spiritlessness and sparing of words, poor appetite lack of appetite, distension and fullness in the abdomen, tie in the stasis of blood poison and cause, card for deficiency in origin and excess in superficiality, so with strengthening spleen, tonifying kidney, dissolving blood stasis and detoxication is the rule of treatment, start with from treating both the principal and secondary aspects of a disease, can obviously improve body fluid and cellular immunization function, thereby enhancing resistance against diseases, but and physical strength reinforcing.This combination preparation is that the crude drug that comprises following weight portion ratio is made:
Radix Astragali 120-360 part Fructus Ligustri Lucidi 100-300 part Radix Ginseng 30-95 part
Ganoderma 30-95 part Rhizoma Curcumae 65-195 part Rhizoma Atractylodis Macrocephalae (stir-fry) 30-90 part
Herba Scutellariae Barbatae 65-195 part Herb Gynostemmae Pentaphylli 120-360 part Poria 30-95 part
Endothelium Corneum Gigeriae Galli 15-45 part Herba Duchesneae Indicae 65-195 part Herba Solani Lyrati 65-195 part
Herba Artemisiae Scopariae 65-195 part Radix Cynanchi Paniculati 65-195 part Eupolyphaga Seu Steleophaga 10-30 part
Herba Hedyotidis Diffusae 65-195 part.
Described foster positive removing food stagnancy drug combination preparation, its proportion of composing comprises:
65 parts of 65 portions of Ganodermas of 200 parts of Radix Ginsengs of 250 parts of Fructus Ligustri Lucidi of the Radix Astragali
128 parts of 64 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 30 portions of Herba Duchesneae Indicaes of 65 parts of Endothelium Corneum Gigeriae Galli of 256 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
20 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Describedly support positive removing food stagnancy drug combination preparation, its form also can comprise Radix Codonopsis, Colla Plastri Testudinis, Fructus Psoraleae, rhizoma sparganic, Radix Ophiopogonis, Fructus Lycii, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Radix Rehmanniae Preparata, Rhizoma Zingiberis, Semen Persicae, Radix Rehmanniae, the Rhizoma Anemarrhenae, Fructus Crataegi, Fructus Hordei Germinatus, the Cortex Eucommiae wherein one or more.
Above-mentioned preparation method of supporting positive removing food stagnancy drug combination preparation comprises:
(1), Radix Ginseng, Fructus Ligustri Lucidi press the recipe quantity weighing, adds 8 times of amount 70% alcohol reflux 2 times, 3 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol to there not being the alcohol flavor, Radix Ginseng, Fructus Ligustri Lucidi residue are standby;
(2), Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati press the recipe quantity weighing, united extraction volatile oil is carried the oil time and is no less than 8 hours, oil yield is not less than 1 ± 0.1%, volatile oil device is in addition collected, residue and aqueous solution are standby;
(3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli two flavor animal drugs press the recipe quantity weighing, washing is taken out, and is put in the interior 60 ℃ of oven dry of drying baker, is broken into 100 order powder with the recipe quantity Poria powder, in 3KGY
60Co-gamma-radiation sterilization back is standby;
(4), the Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae is totally eight flavor medicines, take by weighing by recipe quantity, with gained Radix Ginseng in the step (1), residue after the alcohol extraction of Fructus Ligustri Lucidi, and gained Rhizoma Curcumae in the step (2), the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati is carried oil back residue and aqueous solution merges, add 9 times of water gagings, heating decocts 2 times, each 2 hours, merge decoction liquor, add gained Radix Ginseng in the step (1), the Fructus Ligustri Lucidi alcohol extract, be condensed into relative density 1.20-1.25 (60 ℃ of heat are surveyed) clear paste, and put into vacuum drying oven, at temperature 60-70 ℃, dry under the vacuum 0.90-0.96Kpa condition, be ground into 100 order powder, paste-forming rate is 16.3 ± 1%, and is standby;
(5), the volatile oil with gained Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati in the step (2) sprays in the fine powder of gained Poria in the step (3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli three flavor medical materials, mixing, fine powder mixing with the medical material extractum of the gained Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae eight flavor medicines in the step (4), airtight half an hour, encapsulated or as the raw material of tablet, the watered pill, electuary and other oral formulations.
Foster positive removing food stagnancy medicament composition capsule of the present invention has the cellular immunization of enhancing and humoral immunization, increases the curative effect of cancer therapy drug, alleviates the function of toxic and side effects of chemoradiotherapy.Pharmacological room of Tumour Inst., Chinese Medical Academy has carried out experimental study to this medicine, and the result is as follows:
Foster positive removing food stagnancy capsule shows the measurement result of mice body's immunity index, can obviously improve cell immune function of human body (lymphocyte transformation, IL-2, the DNCB delayed hypersensitivity, the NK cell killing activity), promote the non-specific phagocytic function of body (net is knitted endothelial system and engulfed the carbon effect of cleaning up not), and can significantly increase humoral immunity of organism function (hemolysin content).Above-mentioned all index learned processing by statistics, all shows significant difference.This medicament composition capsule has significant protective effect to liver dysfunction due to the carbon tetrachloride; Mice peripheral leukocytes counting decline due to the CTX there is the certain protection effect; Total irradiation has protective action to mice lethal dose X line; Can increase the tumor-inhibiting action of CTX, alleviate the side effect that CTX causes, improve the anti-anoxia ability of breaking of mice; Used dosage does not show side effect.
This medicament composition capsule is under the condition of 0.625g/kg, 2.5g/kg and three kinds of dosage of 10g/kg, the growth of mouse entity tumor S180, rat liver cancer HAC and Mice Bearing Lewis Lung Cancer all there is in various degree inhibitory action, and along with the increase inhibitory action of dosage strengthens, in the test that Human Gastric Cancer MKN-45 carried out of transplanting in nude mice, the result confirms that equally this medicament composition capsule has antitumor action.
Low dose of this drug combination preparation and low dose of chemotherapeutics cyclophosphamide, methotrexate and mitomycin merge to be used, calculate through WebbShi mark product method, low dose of this medicament composition capsule and above-mentioned three kinds of structures are totally different, the diverse chemotherapeutics of pharmacological mechanism all has synergism, has shown the purposes on the other hand of this medicament composition capsule " eliminating evil " effect.
This medicine composite for curing all has certain facilitation to the immunologic function of normal mouse and tumor-bearing mice, can promote spleen lymphocyte proliferation, activates the NK cytoactive, promotes the generation of IL-2.
This drug combination preparation reduces the effect that certain leukocyte increasing is arranged to the murine interleukin that heavy dose of cyclophosphamide causes.
The specific embodiment
Example below in conjunction with drug regimen of the present invention illustrates the specific embodiment of the present invention.
Embodiment 1:
65 parts of 65 portions of Ganodermas of 200 parts of Radix Ginsengs of 250 parts of Fructus Ligustri Lucidi of the Radix Astragali
128 parts of 64 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 30 portions of Herba Duchesneae Indicaes of 65 parts of Endothelium Corneum Gigeriae Galli of 256 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
20 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method:
(1), Radix Ginseng, Fructus Ligustri Lucidi press the recipe quantity weighing, adds 8 times of amount 70% alcohol reflux 2 times, 3 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol to there not being the alcohol flavor, Radix Ginseng, Fructus Ligustri Lucidi residue are standby;
(2), Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati press the recipe quantity weighing, united extraction volatile oil is carried the oil time and is no less than 8 hours, oil yield is not less than 1 ± 0.1%, volatile oil device is in addition collected, residue and aqueous solution are standby;
(3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli two flavor animal drugs press the recipe quantity weighing, washing is taken out, and is put in the interior 60 ℃ of oven dry of drying baker, is broken into 100 order powder with the recipe quantity Poria powder, in 3KGY
60Co-gamma-radiation sterilization back is standby;
(4), the Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae is totally eight flavor medicines, take by weighing by recipe quantity, with gained Radix Ginseng in the step (1), residue after the Fructus Ligustri Lucidi alcohol extraction, and gained Rhizoma Curcumae in the step (2), the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati is carried oil back residue and aqueous solution merges, add 9 times of water gagings, heating decocts 2 times, each 2 hours, merge decoction liquor, add gained Radix Ginseng in the step (1), the Fructus Ligustri Lucidi alcohol extract, be condensed into relative density 1.20-1.25 (60 ℃ of heat are surveyed) clear paste, and put into vacuum drying oven, at temperature 60-70 ℃, dry under the vacuum 0.90-0.96Kpa condition, be ground into 100 order powder, paste-forming rate is 16.3 ± 1%, and is standby;
(5), the volatile oil with gained Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati in the step (2) sprays in the fine powder of gained Poria in the step (3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli three flavor medical materials, mixing, fine powder mixing with medical material extractum such as the gained Radix Astragali in the step (4), airtight half an hour, obtain the preparation base stock.
(6), encapsulated, trade name is for supporting positive removing food stagnancy capsule (original name deity supposed to be a chaser of demons's capsule).
Embodiment 2:
30 parts of 30 portions of Ganodermas of 100 parts of Radix Ginsengs of 120 parts of Fructus Ligustri Lucidi of the Radix Astragali
65 parts of 30 portions of Herba Scutellariae Barbataes of 65 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
65 parts of 15 portions of Herba Duchesneae Indicaes of 30 parts of Endothelium Corneum Gigeriae Galli of 120 parts of Poria of Herb Gynostemmae Pentaphylli
10 parts of 65 parts of Eupolyphaga Seu Steleophagas of 65 parts of Radix Cynanchi Paniculatis of 65 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
65 parts of Herba Hedyotidis Diffusaes.
Preparation method: with embodiment 1.
Embodiment 3:
95 parts of 95 portions of Ganodermas of 300 parts of Radix Ginsengs of 360 parts of Fructus Ligustri Lucidi of the Radix Astragali
195 parts of 90 portions of Herba Scutellariae Barbataes of 195 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
195 parts of 45 portions of Herba Duchesneae Indicaes of 95 parts of Endothelium Corneum Gigeriae Galli of 360 parts of Poria of Herb Gynostemmae Pentaphylli
195 parts of 195 parts of Radix Cynanchi Paniculatis of 195 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
195 parts of 30 parts of Herba Hedyotidis Diffusaes of Eupolyphaga Seu Steleophaga.
Preparation method: (1), (2), (3), (4), (5) with embodiment 1 add the adjuvant tabletting with base stock.
Embodiment 4:
80 parts of 80 portions of Ganodermas of 200 parts of Radix Ginsengs of 200 parts of Fructus Ligustri Lucidi of the Radix Astragali
128 parts of 64 portions of Herba Scutellariae Barbataes of 75 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 30 portions of Herba Duchesneae Indicaes of 65 parts of Endothelium Corneum Gigeriae Galli of 156 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
20 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method: (1), (2), (3), (4), (5) with embodiment 1 add adjuvant with base stock and make electuary.
Embodiment 5:
65 parts of 65 portions of Ganodermas of 150 parts of Radix Ginsengs of 300 parts of Fructus Ligustri Lucidi of the Radix Astragali
80 parts of 64 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 18 portions of Herba Duchesneae Indicaes of 75 parts of Endothelium Corneum Gigeriae Galli of 256 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 80 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
10 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method: (1), (2), (3), (4), (5) with embodiment 1 add adjuvant with base stock and make the watered pill.
Embodiment 6:
65 parts of 95 portions of Ganodermas of 200 parts of Radix Ginsengs of 120 parts of Fructus Ligustri Lucidi of the Radix Astragali
195 parts of 64 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 30 portions of Herba Duchesneae Indicaes of 65 parts of Endothelium Corneum Gigeriae Galli of 360 parts of Poria of Herb Gynostemmae Pentaphylli
195 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
30 parts of 65 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method:, base stock is made powder with (1), (2), (3), (4), (5) of embodiment 1.
Embodiment 7:
95 parts of 95 portions of Ganodermas of 300 parts of Radix Ginsengs of 180 parts of Fructus Ligustri Lucidi of the Radix Astragali
65 parts of 65 portions of Herba Scutellariae Barbataes of 195 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 15 portions of Herba Duchesneae Indicaes of 30 parts of Endothelium Corneum Gigeriae Galli of 256 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
10 parts of 195 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method: (1), (2), (3), (4), (5) with embodiment 1 add the adjuvant oral liquid with base stock.
Embodiment 8:
65 parts of 95 portions of Ganodermas of 300 parts of Radix Ginsengs of 120 parts of Fructus Ligustri Lucidi of the Radix Astragali
128 parts of 90 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalaes of Rhizoma Curcumae (stir-fry)
128 parts of 30 portions of Herba Duchesneae Indicaes of 95 parts of Endothelium Corneum Gigeriae Galli of 120 parts of Poria of Herb Gynostemmae Pentaphylli
65 parts of 65 parts of Radix Cynanchi Paniculatis of 65 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
30 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
Preparation method: with embodiment 1.
The compositions that the preparation method of the foregoing description is made can be used for preparing clinically the base stock of other oral formulations such as tablet, electuary, powder, oral liquid.
Pharmaceutical composition of the present invention is monarch with the Radix Astragali, Fructus Ligustri Lucidi, with Radix Ginseng, Ganoderma, Rhizoma Curcumae, Herb Gynostemmae Pentaphylli is ministerial drug, the Rhizoma Atractylodis Macrocephalae, Poria, Endothelium Corneum Gigeriae Galli, Radix Cynanchi Paniculati, Eupolyphaga Seu Steleophaga, Herba Hedyotidis Diffusae, Herba Duchesneae Indicae, Herba Solani Lyrati are adjuvant drug altogether, Herba Scutellariae Barbatae, Herba Artemisiae Scopariae are for making, can be used as the treatment ancillary drug for resistance type primary hepatocarcinoma in asthenia of both the spleen and kidney, the stasis of blood poison uses, but enhancing human body immunity power is resisted exopathogen, makes the body early recovery.
Claims (3)
1, the positive removing food stagnancy drug combination preparation of a breeding is characterized in that being that the crude drug of following weight portion ratio is made:
Radix Astragali 120-360 part Fructus Ligustri Lucidi 100-300 part Radix Ginseng 30-95 part
Ganoderma 30-95 part Rhizoma Curcumae 65-195 part Rhizoma Atractylodis Macrocephalae is fried 30-90 part
Herba Scutellariae Barbatae 65-195 part Herb Gynostemmae Pentaphylli 120-360 part Poria 30-95 part
Endothelium Corneum Gigeriae Galli 15-45 part Herba Duchesneae Indicae 65-195 part Herba Solani Lyrati 65-195 part
Herba Artemisiae Scopariae 65-195 part Radix Cynanchi Paniculati 65-195 part Eupolyphaga Seu Steleophaga 10-30 part
Herba Hedyotidis Diffusae 65-195 part;
Its preparation method comprises:
(1), Radix Ginseng, Fructus Ligustri Lucidi alcohol reflux, merge extractive liquid, reclaims ethanol to there not being the alcohol flavor, Radix Ginseng, Fructus Ligustri Lucidi residue are standby;
(2), Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati united extraction volatile oil, device is collected in addition, residue and aqueous solution are standby;
(3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli be in 60 ℃ of oven dry, is broken into 100 order powder with the recipe quantity Poria powder, in 3KGY
60Co-gamma-radiation sterilization back is standby;
(4), the Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae totally eight the flavor medicines, with residue after the alcohol extraction of gained Radix Ginseng, Fructus Ligustri Lucidi in the step (1), and gained Rhizoma Curcumae, Rhizoma Atractylodis Macrocephalae (parched), Radix Cynanchi Paniculati are proposed oil back residue and aqueous solution merging in the step (2), add 9 times of water gagings, and heating decocts, merge decoction liquor, add gained Radix Ginseng, Fructus Ligustri Lucidi alcohol extract in people's step (1), be condensed into clear paste, and vacuum drying, be ground into 100 order powder, standby;
(5), in the fine powder with gained Poria, Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli in volatile oil spray people's step (3) of gained Rhizoma Curcumae, Rhizoma Atractylodis Macrocephalae (parched), Radix Cynanchi Paniculati in the step (2), mixing, fine powder mixing with the medical material extractum of gained in the step (4), airtight half an hour, encapsulated or as the raw material of tablet, the watered pill, electuary and other oral formulations.
2, foster positive removing food stagnancy drug combination preparation according to claim 1, its crude drug ratio is:
65 parts of 65 portions of Ganodermas of 200 parts of Radix Ginsengs of 250 parts of Fructus Ligustri Lucidi of the Radix Astragali
128 parts of 64 portions of Herba Scutellariae Barbataes of 132 parts of Rhizoma Atractylodis Macrocephalae (parched)s of Rhizoma Curcumae
128 parts of 30 portions of Herba Duchesneae Indicaes of 65 parts of Endothelium Corneum Gigeriae Galli of 256 parts of Poria of Herb Gynostemmae Pentaphylli
128 parts of 128 parts of Radix Cynanchi Paniculatis of 128 portions of Herba Artemisiae Scopariaes of Herba Solani Lyrati
20 parts of 128 parts of Eupolyphaga Seu Steleophagas of Herba Hedyotidis Diffusae.
3, comprise according to the described preparation method of supporting positive removing food stagnancy drug combination preparation of claim 1:
(1), Radix Ginseng, Fructus Ligustri Lucidi press the recipe quantity weighing, adds 8 times of amount 70% alcohol reflux 2 times, 3 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol to there not being the alcohol flavor, Radix Ginseng, Fructus Ligustri Lucidi residue are standby;
(2), Rhizoma Curcumae, the Rhizoma Atractylodis Macrocephalae (stir-fry), Radix Cynanchi Paniculati press the recipe quantity weighing, united extraction volatile oil is carried the oil time and is no less than 8 hours, oil yield is not less than 1 ± 0.1%, volatile oil device is in addition collected, residue and aqueous solution are standby;
(3), Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli two flavor animal drugs press the recipe quantity weighing, washing is taken out, and is put in the interior 60 ℃ of oven dry of drying baker, is broken into 100 order powder with the recipe quantity Poria powder, in 3KGY
60Co-gamma-radiation sterilization back is standby;
(4), the Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae is totally eight flavor medicines, take by weighing by recipe quantity, with gained Radix Ginseng in the step (1), residue after the alcohol extraction of Fructus Ligustri Lucidi, and gained Rhizoma Curcumae in the step (2), Rhizoma Atractylodis Macrocephalae (parched), Radix Cynanchi Paniculati is carried oil back residue and aqueous solution merges, add 9 times of water gagings, heating decocts 2 times, each 2 hours, merge decoction liquor, add gained Radix Ginseng in people's step (1), the Fructus Ligustri Lucidi alcohol extract, be condensed into the clear paste of relative density 1.20-1.25, and put people's vacuum drying oven, at temperature 60-70 ℃, dry under the vacuum 0.90-0.96Kpa condition, be ground into 100 order powder, paste-forming rate is 16.3 ± 1%, and is standby;
(5), in the fine powder with gained Poria, Eupolyphaga Seu Steleophaga, Endothelium Corneum Gigeriae Galli three flavor medical materials in volatile oil spray people's step (3) of gained Rhizoma Curcumae, Rhizoma Atractylodis Macrocephalae (parched), Radix Cynanchi Paniculati in the step (2), mixing, fine powder mixing with the medical material extractum of the gained Radix Astragali, Ganoderma, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Herb Gynostemmae Pentaphylli, Herba Duchesneae Indicae, Herba Solani Lyrati, Herba Artemisiae Scopariae eight flavor medicines in the step (4), airtight half an hour, encapsulated or as the raw material of tablet, the watered pill, electuary and other oral formulations.
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| CNB2004100123474A CN1255181C (en) | 2004-06-15 | 2004-06-15 | Preparation of medicinal composition for nourishing |
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| CN102210836A (en) * | 2010-04-08 | 2011-10-12 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparation of medicine for treating stomach cancer |
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2004
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102210836A (en) * | 2010-04-08 | 2011-10-12 | 河北以岭医药研究院有限公司 | Application of Chinese medicinal composition in preparation of medicine for treating stomach cancer |
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