CN1253012A

CN1253012A - Medicines for treating osteoporosis and their preparing process

Info

Publication number: CN1253012A
Application number: CN98124694A
Authority: CN
Inventors: 卿多舜
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-11-06
Filing date: 1998-11-06
Publication date: 2000-05-17
Anticipated expiration: 2018-11-06
Also published as: CN1087619C

Abstract

A medicine in the form of tablets for preventing and curing acalcerosis and osteoporosis is prepared on the basis of traditional Chinese medicinal prescription, and features that it is rich in calcium and VD for promoting growth of bone, and has satisfactory curing effect on acalcerosis and osteoporosis.

Description

Preparation and preparation methoies such as tablet for treating osteoporosis

The present invention is the preparation of a kind of health care, prevention, treatment osteoporosis.

The osteoporotic cause of disease is: caused by all different reasons, divide constitutional and Secondary cases two big classes.

Primary osteoporosis, because due to the living environment condition, and influence, monophagia, calcium and the needed by human food intake deficiency of gastrointestinal function decline; The Inheritance calcium content of bone is low; Person in middle and old age's phase, the regression of each organ dysfunction of human body, calcium absorption descends, and underutilization, the blood calcium of calcium are low, and it is few that calcium enters bone bank, and bone is rebuild and is descended, and especially Women calcium amount lost is more, can cause osteoporosis.

Secondary osteoporosis has: nephropathy, diabetes, rheumatism, aseptic necrosis, fracture and prolonged illness bed, muscular labor momentum are few, see that sunlight is few, smoking, indulge in excessive drinking, eat bad life habits such as curing food is too much, cause silent osteoporosis to people.

Juvenile era and postadolescence, the bone density peak value does not reach own health normal level, can occur osteoporosis and senilism ahead of time.

Osteoporotic clinical manifestation: it is a kind of commonly encountered diseases, frequently-occurring disease, be to occur in skeletal system bone amount to reduce, follow the multiple disease that merges, as: lumbago and skelalgia, tinnitus, Leg Cramps, arteriosclerosis, blood vessel and soft tissue calcification, hypertension, coronary heart disease, calculus, local aseptic necrosis, hunchback, vertebra and osteoarthrosis compression fracture, slight wound can cause limb fracture.

Theory of Chinese medical science is: imbalance of YIN and YANG, the bone of suffering from a deficiency of the kidney wither, insufficiency of vital energy and blood, lassitude loin and legs; Hyperactivity of fire caused by deficiency of YIN, the heating of five hearts, night sweat; Yang deficiency exogenous cold, qi depression to blood stasis.

The object of the present invention is to provide a kind of preparation that can effectively keep healthy, prevent, treat osteoporosis.

Preparations such as this tablet for treating osteoporosis are according to above-mentioned pathogeny and clinical symptoms and check and determine therapeutic scheme, extract classical from pools of traditional Chinese medicine, the experience prescription, with calcic, the more Chinese medicine of vitamin D, other adds the effect that vitamin D promotes bone growth, worked out and to have kept healthy and to have prevented morbidity, can treat the medicine of osteoporosis again.

Its drug action mechanism is: invigorating the spleen and regulating the stomach, YIN nourishing and YANG strengthening, nourishing the liver and kidney, invigorating the kidney and strengthening the bones, relaxing muscles and tendons to promote blood circulation, anti-inflammatory analgetic, with the contained multiple material essence of Chinese medicine, improving and transferring on the basis of body interior function, the strong bone of replenishing the calcium reaches the osteoporotic purpose of treatment, especially promote healing to play good effect to fracture, through a large amount of clinical verifications, this medicine composition is reasonable, safe and feasible, can play health care, prevent, treat osteoporotic effect, reached promising result, take three months medicines, obvious effective rate reaches 91%.

In the present invention, the component of this anti-bone pine preparation be Os Draconis, Concha Ostreae, Radix Angelicae Sinensis, Fructus Psoraleae, Rhizoma Chuanxiong, Herba Epimedii, Fructus Ligustri Lucidi, Carapax Trionycis, in one or more each 0.10g-1.5g, each 0.1g-0.8g of in Ganoderma, Radix Panacis Quinquefolii, Fructus Lycii, Placenta Hominis, Testis Caprae seu Ovis, Eupolyphaga Seu Steleophaga, Scorpio, the Radix Glycyrrhizae one or more, the amount of above-mentioned composition is one day a consumption of general adult.

In the present invention, each 10-70 gram of in Os Draconis, Concha Ostreae, Carapax Trionycis, Fructus Psoraleae, Scorpio, Eupolyphaga Seu Steleophaga, Radix Panacis Quinquefolii, Placenta Hominis, Fructus Ligustri Lucidi, the Testis Caprae seu Ovis one or more is ground into fine powder, and one or more 10g-110g water decoction filtering and concentrating and above-mentioned fine powder in Radix Angelicae Sinensis, Ganoderma, Rhizoma Chuanxiong, Herba Epimedii, Fructus Lycii, the Radix Glycyrrhizae are mixed and made into tablet, pill, capsule and oral liquid.

The present invention will further specify by embodiment

Embodiment one Fructus Ligustri Lucidi 0.15g Herba Epimedii 0.6g Placenta Hominis 0.15g Testis Caprae seu Ovis 0.15g Radix Panacis Quinquefolii 0.15g Ganoderma 0.15g Os Draconis 0.6g Concha Ostreae 0.6g Carapax Trionycis 0.3g Fructus Psoraleae 0.6g Fructus Lycii 0.15g Eupolyphaga Seu Steleophaga 0.15g Rhizoma Chuanxiong 0.6g Radix Angelicae Sinensis 0.6g Scorpio 0.15g Radix Glycyrrhizae 0.15g

Wherein vitamin D, Os Draconis, Concha Ostreae, Carapax Trionycis, Fructus Psoraleae, Scorpio, Eupolyphaga Seu Steleophaga, Radix Panacis Quinquefolii, Placenta Hominis, Fructus Ligustri Lucidi, Testis Caprae seu Ovis, be ground into fine powder, Radix Angelicae Sinensis, Ganoderma, Rhizoma Chuanxiong, Herba Epimedii, Fructus Lycii, Radix Glycyrrhizae decoct with water three times, 3 hours for the first time, second and third time each 2 hours, merge decoction filtering then, the molten thick paste that shortens into of filtrate is with the even drying and crushing of above-mentioned fine powder, make granule, suppress in blocks or encapsulated and pill etc.

Embodiment two Fructus Ligustri Lucidi 0.75g Herba Epimedii 1.35g Placenta Hominis 0.75g Testis Caprae seu Ovis 0.75g Radix Panacis Quinquefolii 0.75g Ganoderma 0.75g Os Draconis 1.35g Concha Ostreae 1.35g Carapax Trionycis 0.75g Fructus Psoraleae 1.35g Fructus Lycii 0.75g Eupolyphaga Seu Steleophaga 0.75g Rhizoma Chuanxiong 1.35g Radix Angelicae Sinensis 1.35g Scorpio 0.75g Radix Glycyrrhizae 0.75g make sheet or other dosage form by embodiment one described formulation method.

The present invention is used for the health care of medical field and treatment medicine, tablet for treating osteoporosis is characterized in: this medicine is by Chinese medicine and contain calcareous Chinese medicine, made tablet has invigorating the spleen and regulating the stomach, YIN nourishing and YANG strengthening, nourishing the liver and kidney, the five internal organs effect of benefit, relaxing muscles and tendons to promote blood circulation, inducing diuresis to remove edema, anti-inflammatory analgetic, invigorating the kidney and strengthening the bones, the strong bone of replenishing the calcium together.This medicine is to replenish the calcium comprehensively taking good care of on the running basis of each organ dysfunction of health again, fundamentally treats osteoporotic purpose to reach.Each age level shows that bone density lowers and sclerotin edge hypertrophy, bone density measurement are to be lower than normal value as the X skiagram, with have a pain in the leg, cramp etc., as long as under physician guidance, take by the medicine explanation, generally have no side effect.To calcium low and osteoporotic human therapy person can reach promising result.

Advantage is: 1, pharmaceutical factory with good conditionsi can both production and processing, is widely used, and considerable benefit is easy to promote; 2, carry taking convenience, safe and reliable, no negative interaction.

Claims

1. osteoporosis preparation, it is characterized in that its component be Os Draconis, Concha Ostreae, Radix Angelicae Sinensis, Fructus Psoraleae, Rhizoma Chuanxiong, Herba Epimedii, Fructus Ligustri Lucidi, Carapax Trionycis, in one or more each 0.1g-1.5g, each 0.1g-0.8g of one or more in Ganoderma, Radix Panacis Quinquefolii, Fructus Lycii, Placenta Hominis, Testis Caprae seu Ovis, Eupolyphaga Seu Steleophaga, Scorpio, the Radix Glycyrrhizae.

2. according to the preparation of claim 1, it is characterized in that the excessive sheep 0.6g of Fructus Ligustri Lucidi 0.15g Placenta Hominis 0.15g Testis Caprae seu Ovis 0.15g Radix Panacis Quinquefolii 0.15g Ganoderma 0.15g Os Draconis 0.6g Concha Ostreae 0.6g Carapax Trionycis 0.3g Fructus Psoraleae 0.6g Fructus Lycii 0.15g Eupolyphaga Seu Steleophaga 0.15g Rhizoma Chuanxiong 0.6g Radix Angelicae Sinensis 0.6g Scorpio 0.15g Radix Glycyrrhizae 0.15g.

3. according to the preparation of claim 1, it is characterized in that Fructus Ligustri Lucidi 0.75g Herba Epimedii 1.35g Placenta Hominis 0.75g Testis Caprae seu Ovis 0.75g Radix Panacis Quinquefolii 0.75g Ganoderma 0.75g Os Draconis 1.35g Concha Ostreae 1.35g Carapax Trionycis 0.75g Fructus Psoraleae 1.35g Fructus Lycii 0.75g Eupolyphaga Seu Steleophaga 0.75g Rhizoma Chuanxiong 1.35g Radix Angelicae Sinensis 1.35g Scorpio 0.75g Radix Glycyrrhizae 0.75g.

4. the formulation method of an anti-bone pine preparation, it is characterized in that one or more each 10 grams-70 grams in Os Draconis, Concha Ostreae, Carapax Trionycis, Fructus Psoraleae, Scorpio, Eupolyphaga Seu Steleophaga, Radix Panacis Quinquefolii, Placenta Hominis, Fructus Ligustri Lucidi, the Testis Caprae seu Ovis are ground into fine powder, one or more 10 gram-110 gram water decoctions in Radix Angelicae Sinensis, Ganoderma, Rhizoma Chuanxiong, Herba Epimedii, Fructus Lycii, the Radix Glycyrrhizae filter, concentrate and above-mentioned fine powder is mixed and made into preparation.

5. according to the method for claim 4, it is characterized in that decocting divides to boil for three times that 3 hours for the first time, second and third time each 2 hours merged decoction liquor then and concentrate.