CN1250384A - Improved inhalation apparatus - Google Patents

Improved inhalation apparatus Download PDF

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Publication number
CN1250384A
CN1250384A CN 98803303 CN98803303A CN1250384A CN 1250384 A CN1250384 A CN 1250384A CN 98803303 CN98803303 CN 98803303 CN 98803303 A CN98803303 A CN 98803303A CN 1250384 A CN1250384 A CN 1250384A
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CN
China
Prior art keywords
air flow
suction apparatus
flow controller
dispenser container
pressurised dispenser
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 98803303
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Chinese (zh)
Inventor
贾森·R·德金
安吉拉·S·菲利普斯
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Consort Medical PLC
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Bespak PLC
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Publication date
Application filed by Bespak PLC filed Critical Bespak PLC
Publication of CN1250384A publication Critical patent/CN1250384A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

An inhalation apparatus (1) for dispensing a product comprises a housing (2) for a pressurized dispensing container (3) and including a portion (8) adapted to receive a valve stem (9) of the pressurized dispensing container, an air inlet to said housing and a mouthpiece (7). The apparatus further comprises duct means communicating with the housing for conveyance of product towards the mouthpiece, and an air flow controller in the form of an annular membrane (12) adjacent to the valve stem receiving portion. The air flow controller (12) is biased to a first position corresponding to no or a minimum flow of air from the air inlet to the mouthpiece, and is movable in use by the pressurized dispensing container to a second position corresponding to a maximum flow of air from the air inlet to the mouthpiece, continued movement of the pressurized dispensing container causing a dose of product to be dispensed into the maximum air flow, the air flow being created by a user applying suction to the mouthpiece.

Description

Improved suction apparatus
The present invention relates to one and be used to distribute the suction apparatus that sucks used material, particularly, but is not unique, is used for distributing from a pressurised dispenser container suction apparatus of the drug products of aerosol shape.
Know, a pick off is set in a suction apparatus, to detect the suction of user, so that make the release of material in inhaled air stream that is inhaled into synchronous with suction.For example in the administration of the aerosol product that is used for alleviating asthma, importantly, distribute the timing of operation should be controlled carefully, so that maximum electrodeposition substance is arranged in the lung of user.
Know from GB 2266466 that a kind of distributor of electricity operation is provided, and it reacts to the signal that is sent by pick off, and this pick off reacts to the air flow through path.The shortcoming of this solution is the device costliness.
One object of the present invention has wherein adopted machinery for a kind of distributor is provided, so that the release of material is coordinated mutually with suction.
Therefore, the invention provides a kind of suction apparatus that is used for allocated product, it comprises that one is used for the seat of pressurised dispenser container and comprises that one is used to admit the valve rod of pressurised dispenser container, the air intake of above-mentioned seat and the part of an interface, said apparatus further comprises a pipe guide and an air flow controller adjacent with the valve rod receiving portion, pipe guide is communicated with seat, be used for towards the interface conveying products, above-mentioned air flow controller be biased to one with do not have air flow from air intake to interface or minimum air flow corresponding first location arranged, and in use can by pressurised dispenser container move to one with the maximum corresponding second position of air flow is arranged from air intake to interface, continue the movement pressure dispense container, the product of a dosage is assigned in the maximum air flow, and air flow is produced by the user that applies suction to interface.
An advantage of the present invention is that the distribution of medicine is synchronous with the suction of the user that uses not expensive suction apparatus.Another advantage is, the air flow of existence allows minimum volume of air flow to enter interface through seat and enters mouth of user, even the position that air flow controller is in first, seals.Such benefit is that it helps to prevent user alarmed danger owing to the air that can not suck any amount.
The volume flow of minimum air flow is preferably less than the volume flow of maximum air flow.
Maximum volume flow is preferably 8~12 times of minimum volume flow.
The advantage of second volume flow that ratio first volume flow that strengthens is big is just setting up a competent air flow before pressurised dispenser container discharging product, to be deposited in the lung of user with the permission drug particles the biglyyest.
Air flow controller preferably include one can with the part of the preceding end in contact of pressurised dispenser container.
An advantage of the present invention is that the operation of air flow controller is carried out with contacting of air flow controller by the front end of pressurised dispenser container.The height change that has been found that the pressurised dispenser container of calculating by tip to the container bottom from valve rod can be by several millimeters changes.An advantage of the present invention is, this variation of the height of pressurised dispenser container can not influence the operation of air flow controller and the timing that product discharges along with the foundation of second air flow, this is because air flow controller is from the front-end driven of pressurised dispenser container.
In one first embodiment, air flow controller comprises a circular membrane, the latter comprises the rib and a neighboring of one or more protuberances, rib is positioned on the upper surface of circular membrane, be used in use preceding end in contact with pressurised dispenser container, neighboring and seated connection close, so that do not have air flow betwixt or minimum air flow is arranged; The neighboring is to the mobile response of rib of protuberance, moves into seat to disengage, to allow that maximum air flow process is arranged betwixt.
The advantage of first embodiment is that Unit Installation is categorical, and the height change of the operation of device and pressurised dispenser container is irrelevant.Another advantage is that air flow controller is hidden to user, thereby damages not too easily.
The radial rib that the rib of protuberance preferably swells, it extends from the core of circular membrane basically, arrives the neighboring substantially always.
Another kind of scheme is, the rib of protuberance is the concentric round rib of one or more protuberance, and it radially separates each other from the core of circular membrane, arrives the neighboring substantially always.
In a second embodiment, air flow controller comprises that one can shelter the columniform sleeve that is roughly in present, sleeve is uncovered in the upper end, to be used to admit pressurised dispenser container, one horizontal film is arranged in its lower end, first section first that comprises air flow controller of horizontal film, it can be with the preceding end in contact of pressurised dispenser container and therewith moves, second section second portion that comprises air flow controller of horizontal film, above-mentioned second section engages in primary importance with air flow controller with first section, so that do not have air flow betwixt or minimum air flow is arranged; First section deflection with respect to second section allows the slit of maximum air flow through so forming between first and second sections of horizontal film.
The advantage of second embodiment is that Unit Installation is categorical, and the height change of the operation of device and pressurised dispenser container is irrelevant.
In the 3rd embodiment, air flow controller comprises a plunger valve, and it has an actuator that is biased to extended position, and above-mentioned actuator can be with the preceding end in contact of pressurised dispenser container and therewith moved; Offseting downward of actuator opened plunger valve and allowed to set up betwixt maximum air flow.
The advantage of this embodiment is that second air intake is not opened gradually, but allows second air flow promptly to set up.Another advantage is, the operation of device and the height change of dispense container are irrelevant, and assembly hides user, therefore not too can damage.
Plunger valve preferably includes a dsah-pot assembly, and to be used for delaying moving up of actuator later at hydraulic actuator down, above-mentioned dsah-pot postpones closing of plunger valve.
Adopt the advantage of dsah-pot assembly to be, the closing of second air intake can be delayed to user and unclamp pressurised dispenser container later some seconds.Such benefit is even it allows the user of device stopping to unclamp pressurised dispenser container mistakenly before the suction, also can continue to suck the medicine of distribution.The drug deposition that can make larger proportion like this is in the lung of user and help the maloperation of anti-locking apparatus.
In the 4th embodiment, air flow controller comprises that one is used for the skirt section with the preceding end in contact of pressurised dispenser container, and this skirt section comprises the one or more edges of a wing that are used for the key that engages with the cannelure of seat and one or more downward extension; The above-mentioned edge of a wing comprises the projection of one or more protuberances, and the opening that it is used for when air flow controller is in primary importance on the partition with seat engages; Partition with seat be used to admit the part of pressurised dispenser container and interface to separate; The skirt section is moved downward to the second position of air flow controller, makes projection not to the opening sealing, to allow to set up the air flow from the maximum of its process.
The advantage of the 4th embodiment is: air flow controller needn't seal big surface area, thereby can set up more reliable sealing.
The process discharge orifice that minimum air flow is best.
Device preferably also comprises a pressurised dispenser container.
As just example preferred embodiment of the present invention is described with reference to the drawings now.
Fig. 1 is the cutaway view of the first embodiment of the present invention;
Fig. 2 is the decomposition diagram of the first embodiment of the present invention;
Fig. 3 is the cutaway view of the second embodiment of the present invention;
Fig. 4 is the decomposition diagram of the second embodiment of the present invention;
Fig. 5 a is the cutaway view of the third embodiment of the present invention;
Fig. 5 b is an enlarged detail view of the present invention;
Fig. 6 is the decomposition diagram of the third embodiment of the present invention;
Fig. 7 a is the cutaway view of the fourth embodiment of the present invention;
Fig. 7 b is an enlarged detail view of the present invention;
Fig. 8 is the decomposition diagram of the fourth embodiment of the present invention.
Referring to Fig. 1 and 2, the first embodiment of the present invention comprises a device 1, this device comprises one 2, seat 2 is made up of a cylindrical portions may 6 and an interface 7, cylindrical portions may 6 is uncovered in the top, so that air can access to plant 1 and admitted a cylindrical pressure dispense container 3, interface 7 stretches out from the lower end of cylindrical portions may 6.Interface 7 can cross out from the cylindrical portions may 6 of seat, or stretches out from cylindrical portions may 6 with slightly downward angle with another kind of scheme.When inserting in the cylindrical portions may 6 with container 3, a gap 5 is arranged between the inner surface of container 3 and cylindrical portions may 6, it is used to allow air to flow through from it.
Seat 2 also comprises a pole socket 8, and it is used to admit the valve rod 9 of pressurised dispenser container 3.Pole socket 8 is traditional structures, and comprises a hole by the open communication on the sidewall of a conduit and saddle, to guide the aerosol spraying when the direction of the outlet 11 of interface 7 is discharged through valve rod 9 on the edge.
One circular membrane 12 engages hermetically with the top of pole socket 8.The cross section of circular membrane 12 is planar shaped substantially, and comprises a centre bore 13.The shape of cross section of centre bore 13 is preferably identical with the shape of cross section of pole socket 8.When apparatus for assembling 1, circular membrane 12 was by partly or wholly pushing away centre bore 13 with pole socket 8 and engaging hermetically with pole socket 8.The external diameter of circular membrane 12 rod seats 8 is held in place, and the internal diameter of the centre bore 13 of circular membrane 12 then is an interference fit.The diameter of circular membrane 12 will be made like this so that the periphery 18 of film 12 when a primary importance because interference fit and engaging with the inner surface of the cylindrical portions may 6 of seat 2.Like this, air flue is blocked in acting as of circular membrane 12 substantially, makes air not enter interface 7 from the cylindrical portions may 6 of seat 2.On circular membrane 12, a discharge orifice can be set, enter interface 7 from the open end of seat 2 with the air flow that allows minimum.Another kind of scheme is that the sealing between circular membrane 12 and the seat 2 can be designed to allow the air of minute quantity to pass through from it.Circular membrane 12 is controlled air through the time of suction apparatus 1 and the air flow controller of flow together with the effect of the inner surface of seat 2 as one.Film 12 can be with polypropylene with excellent sealing performance or the manufacturing of a kind of soft bullet colloid.
Circular membrane 12 further comprises the rib 14 of many protuberances on the upper surface of circular membrane 12.The effect of radial rib 14 is as means that film 12 bent into when the operative installations 1 second position, and provides structural strength at sealing station to film 12.The rib 14 of protuberance can be radial, can be concentric circular by another kind of scheme also.The shape of the rib 14 of protuberance can be a triangle on vertical, and a summit 15 is arranged, and its position is towards centre bore 13, so that contact with the front end 16 of pressurised dispenser container 3 in use.Rib 14 can have the different shape of the operation that does not influence air flow controller.In the place of the close valve rod 9 in the end of pressurised dispenser container 3, the front end 16 of pressurised dispenser container 3 comprises other surface of lasso and pressurised dispenser container 3.If adopt concentrically ringed rib, then the rib of the most close centre bore 13 more swells than the rib of the most close periphery 18.
In use, user is placed on interface 7 in his mouth and sucks.Engage with seat 2 with circular membrane 12 in primary importance, just might not have a lot of air flows through air flow controller.After, user is just toward down force pressure dispense container 3.The front end 16 that makes container 3 when valve rod 9 begins to slide that moves downward of container 3 contacts with the summit 15 of the rib of protuberance.The rib 14 that further the offseting downward of pressure vessel 3 makes protuberance is bent to the second position with circular membrane 12 from primary importance.Because the core of circular membrane 12 is the tops that are fixed on pole socket 8 hermetically, thus the center of circular membrane 12 than the outer peripheral part 17 of circular membrane 12 is crooked must be smaller.When neighboring 18 moves down, allow air when the upper end of opening wide of seat 2 flows into interface 7 and flow export 11 through the gap between neighboring 18 and the seat 2, the bending of film 12 makes the internal diameter blow-by of periphery 18 and the cylindrical portions may 6 of seat 2.
Further, just, make film 12 be bent to one the 3rd position, and the medicine of a dosage is discharged through valve rod 9 and valve rod base 8 further toward pressing down valve rod 9 through pressing down dispense container 3.Dispense container 3 can be crossed the 3rd position and be moved, but this can't influence the operation of device 1.After having set up through the air flow of inhaler, with regard to discharge of medicament, and drug particles is entrained in the air flow like this and is inhaled into.Will be appreciated that, in this embodiment and the embodiment that will describe afterwards, the valve rod 9 needed necessary long enoughs of stroke that are used for operating pressure dispense container 3 are so that allow air flow controller to move to the 3rd position from primary importance before the medicine of a dosage of pressurised dispenser container 3 dischargings.
On the primary importance of the inner surface that seals up cylindrical portions may 6 with circular membrane 12, wish to enter through inhaler the mouth of user when interface 7 applies suction at the air flow that a minimum is arranged.The air flow of this minimum helps to prevent the issuable any panic sense in the time can not sucking air in certain amount of inhaler user.The volume of air flow of this minimum can produce with a discharge orifice by combination on circular membrane 12.Another kind of scheme is that minimum volume of air flow can be by being designed to circular membrane (12) have the leakage air of a minimum to be guaranteed through neighboring 18 at sealing state.Like this, at the state (film is in primary importance) that does not move, inhaler has minimum volume of air flow through inhaler, and when circular membrane 12 has been bent to the second position, maximum volume of air flow is arranged through inhaler.Maximum ratio with volume of air flow minimum can change widely, and the character of the sealing contact of size that can be by changing discharge orifice and/or circular membrane 12 is regulated.Maximum ratio with volume of air flow minimum is preferably in 8~12 the scope, and maximum ratio with volume of air flow minimum is preferably about 10.
Another embodiment of the present invention is described now.The common part of another embodiment and first embodiment is represented with same reference number.
Shown in Fig. 3 and 4, in the second embodiment of the present invention, air flow controller 20 comprises a deformable member 21, the latter comprises a cylindrical sleeve 22, this sleeve is uncovered in the top, is used to admit pressurised dispenser container 3, seals with a horizontal film 23 in its lower end.Cylindrical sleeve 22 topmost is contained on the seat 2 hermetically at it.This sealing is preferably in the top of cylindrical portions may 6 and makes.But, sealing also can be above horizontal film 23 any point of present 2 cylindrical shape part 6 make.Laterally film 23 comprises a centre bore 13, and dispense container 3 is being inserted in the device 1, and the valve rod 9 of dispense container 3 passes from this hole.Laterally film 23 further comprises a second portion 27 that separates with the annular construction member 26 bonded firsts 25 that surround centre bore 13 and the many slits 28 on the horizontal film 23 of a usefulness and first 25.In the position of not moving, first and second parts 25,27 are engaged with each other, and cross horizontal film 23 to prevent any big air flow.When pressing down dispense container 3, the front end 16 of dispense container 3 contacts and makes annular construction member 26 and first 25 to be bent to the second position from primary importance downwards with annular construction member 26.Therefore, laterally the second portion 27 of film 23 separates with first 25, and when first 25 was bent downwardly to the second position with annular construction member 26, opened in slit 28, allows maximum air mass flow to pass slit 28 when interface 7 applies suction at user.
Further toward pressing down dispense container 3,, make horizontal film 23 be bent to the 3rd position and the medicine of a dosage is discharged through valve rod 9 and valve rod base 8 just further toward pressing down valve rod 9.After having set up through the maximum air flow of inhaler, with regard to discharge of medicament, and drug particles is entrained in the air flow like this and is inhaled into.
Laterally film 23 preferably has a upwardly extending dome-shaped configuration in primary importance.This configuration is biased into horizontal film 23 with the front end 16 of dispense container 3 and contacts.This bias effect guarantees that also slit 28 closes again when unclamping dispense container 3.Deformable member 21 the most handy polymer manufacturings as the polypropylene.
Can on first or second portion 27, make discharge orifice, or, can become to allow minimum volume of air flow to pass through the INTERFACE DESIGN between first and second parts 25,27 from it by another kind of scheme.
In Fig. 5 a, 5b and 6, the third embodiment of the present invention has been shown.The plunger valve 30 of one traditional structure is set near pole socket 8.Plunger valve 30 comprises an actuator 31, and 3 front end 16 extends upward from plunger valve 30 towards dispense container for it.In the primary importance of plunger valve 30, actuator is biased to the position that protrudes upward.Seat 2 further cylindrical portions may 6 comprise a partition 32 bottom, it with cylindrical portions may 6 with respect to interface 7 sealings.In use, when user when interface 7 applies suction, toward pressing down dispense container 3, the actuator lever 31 of plunger valve 30 is just by front end 16 past pressing down, from primary importance to the second position, plunger valve 30 is opened, and allow maximum air flow from the opening end on the top of seat 2 through plunger valve 30, through the groove 33 of the either side of pole socket 8, flow in the interface 7.
Further toward pressing down dispense container 3, just further with plunger valve 30 toward pressing to the 3rd position, and the medicine of a dosage is discharged through valve rod 9 and valve rod base 8.After having set up through the maximum air flow of inhaler, with regard to discharge of medicament, and drug particles is entrained in the air flow like this and is inhaled into.
Plunger valve 30 is can right and wrong traditional, and comprises a dsah-pot assembly, and the latter is delaying protruding upward of actuator 31 with dispense container 3 after pressing down actuator lever 31.Like this, closing of plunger valve 30 and stopping and after unclamping dispense container 3, to postpone the known time of air flow, such benefit is, if the user of suction apparatus unclamped dispense container 3 mistakenly before finishing the suction circulation, then the air flow through suction apparatus has can not stop several seconds, thereby allows user can finish the suction of the medicine that is discharged.
The fourth embodiment of the present invention is shown in Fig. 7 a, 7b and 8.One deformable skirt section 40 is set, is used to admit the front end 16 of dispense container 3.Skirt section 40 comprises a centre bore 13, and valve rod 9 passes that this hole is stretched out and engages with valve rod base 8.Skirt section 40 further comprises one or more key 47, and the latter is received within the groove 48 on the inner surface of cylindrical portions may 6.Key 47 prevents skirt section 40 rotations when engaging with groove 48.Skirt section 40 further comprises an edge of a wing 42 of extending downwards, and the latter has a projection 43 on a vertical surface.Projection 43 can be made the shape of the lump of protuberance.40 the primary importance in the skirt section, projection 43 engage with opening 44 on the partition 50 of seat 2 hermetically.Partition 50 separates interface 7 and cylindrical portions may 6.Skirt section 40 can be with polymer or other deformable material manufacture.
In use, toward pressing down, make skirt section 40 be moved downward to a second position dispense container 3, projection 43 is stepped out from opening 44 simultaneously.This moves by providing from the partition 50 curved edges of a wing 42 of opening.The gap that produces between projection 43 and opening 44 allows minimum air flow to pass suction apparatus when interface 7 applies suction at user and enters interface 7.
Further toward pressing down dispense container 3, make skirt section 40 move to the 3rd position and the medicine of a dosage is discharged through valve rod 9 and valve rod base 8.After having set up through the maximum air flow of inhaler, with regard to discharge of medicament, and drug particles is entrained in the air flow like this and is inhaled into.
40 above water in the skirt section, on present 2 the inner surface restriction 49 is set.Restriction 49 is removed in pressurised dispenser container 3, so that cleaning or prevent that skirt section 40 from being pulled out when changing from seat 2.Make skirt section 40 separate needed power with the front end 16 of pressurised dispenser container 3 less than making skirt section 40 move through restriction 49 needed power.
On skirt section 40, discharge orifice 45 can be set, when suction apparatus is in resting guard, to allow the minimum air mass flow inhaler of flowing through.
Will be appreciated that, can make various modifications and do not depart from the scope of the present invention installing 1 structure.
The advantage of all these embodiment is that air flow controller in use contacts with the front end 16 of pressurised dispenser container 3.Therefore, the height change of the operation of inhaler and dispense container body is irrelevant.But and the distance dependent between the front end 16 of the tip of valve rod 9 and container 3, have been found that this height change by with the similar identical quantitative changeization of the haul distance of valve rod 9, the variation of this distance then has been found that more much smaller than the height change of entire container 3.Like this, the distribution of the medicine of a dosage will be more reliable with respect to the timing of the beginning of the air flow of maximum.

Claims (14)

1. suction apparatus that is used for allocated product, it comprises that one is used for the seat of pressurised dispenser container and comprises that one is used to admit the valve rod of pressurised dispenser container, the air intake of above-mentioned seat and the part of an interface, said apparatus further comprises a pipe guide and an air flow controller adjacent with the valve rod receiving portion, pipe guide is communicated with seat, be used for towards the interface conveying products, above-mentioned air flow controller be biased to one with do not have air flow from air intake to interface or minimum air flow corresponding first location arranged, and in use can by pressurised dispenser container move to one with the maximum corresponding second position of air flow is arranged from air intake to interface, continue the movement pressure dispense container, the product of a dosage is assigned in the maximum air flow, and air flow is produced by the user that applies suction to interface.
2. as the desired suction apparatus of claim 1, it is characterized by, the volume flow of minimum air flow is less than the volume flow of maximum air flow.
3. as the desired suction apparatus of claim 2, it is characterized by, maximum volume flow is 8~12 times of minimum volume flow.
4. each desired suction apparatus of claim as described above is characterized by, air flow controller comprise one can with the part of the preceding end in contact of pressurised dispenser container.
5. each desired suction apparatus of claim as described above, it is characterized by, air flow controller comprises a circular membrane, the latter comprises the rib and a neighboring of one or more protuberances, rib is positioned on the upper surface of circular membrane, be used in use the preceding end in contact with pressurised dispenser container, neighboring and seated connection close, so that do not have air flow betwixt or minimum air flow is arranged; The neighboring is to the mobile response of rib of protuberance, moves into seat to disengage, to allow that maximum air flow process is arranged betwixt.
6. as the desired suction apparatus of claim 5, it is characterized by, the rib of protuberance is the radial rib of protuberance, and it extends from the core of circular membrane basically, arrives the neighboring substantially always.
7. as the desired suction apparatus of claim 5, it is characterized by, the rib of protuberance is the concentric round rib of one or more protuberance, and it radially separates each other from the core of circular membrane, arrives the neighboring substantially always.
8. as each desired suction apparatus of claim 1 to 4, it is characterized by, air flow controller comprises that one can shelter the columniform sleeve that is roughly in present, sleeve is uncovered in the upper end, to be used to admit pressurised dispenser container, one horizontal film is arranged in its lower end, first section first that comprises air flow controller of horizontal film, it can be with the preceding end in contact of pressurised dispenser container and therewith moves, second section second portion that comprises air flow controller of horizontal film, above-mentioned second section engages in primary importance with air flow controller with first section, so that do not have air flow betwixt or minimum air flow is arranged; First section deflection with respect to second section allows the slit of maximum air flow through so forming between first and second sections of horizontal film.
9. as each desired suction apparatus of claim 1 to 4, it is characterized by, air flow controller comprises a plunger valve, and it has an actuator that is biased to extended position, and above-mentioned actuator can be with the preceding end in contact of pressurised dispenser container and therewith moved; Offseting downward of actuator opened plunger valve and allowed to set up betwixt maximum air flow.
10. as the desired suction apparatus of claim 9, it is characterized by, plunger valve comprises a dsah-pot assembly, and to be used for delaying moving up of actuator later at hydraulic actuator down, above-mentioned dsah-pot postpones closing of plunger valve.
11. each desired suction apparatus as claim 1 to 4, it is characterized by, air flow controller comprises that one is used for the skirt section with the preceding end in contact of pressurised dispenser container, and this skirt section comprises the one or more edges of a wing that are used for the key that engages with the cannelure of seat and one or more downward extension; The above-mentioned edge of a wing comprises the projection of one or more protuberances, and the opening that it is used for when air flow controller is in primary importance on the partition with seat engages; Partition with seat be used to admit the part of pressurised dispenser container and interface to separate; The skirt section is moved downward to the second position of air flow controller, makes projection not to the opening sealing, to allow to set up the air flow from the maximum of its process.
12. the desired suction apparatus of each claim is characterized by as described above, minimum air flow is through discharge orifice.
13. the desired suction apparatus of each claim also comprises a pressurised dispenser container as described above.
14. one kind basically as preceding with reference to the accompanying drawings as described in and the suction apparatus that illustrates in the drawings.
CN 98803303 1997-03-14 1998-03-13 Improved inhalation apparatus Pending CN1250384A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9705387.0 1997-03-14
GB9705387A GB2323040A (en) 1997-03-14 1997-03-14 Inhalation apparatus

Publications (1)

Publication Number Publication Date
CN1250384A true CN1250384A (en) 2000-04-12

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CN 98803303 Pending CN1250384A (en) 1997-03-14 1998-03-13 Improved inhalation apparatus

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EP (1) EP0969890A1 (en)
JP (1) JP2001516243A (en)
CN (1) CN1250384A (en)
CA (1) CA2283936A1 (en)
GB (1) GB2323040A (en)
WO (1) WO1998041253A1 (en)

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CN101193676B (en) * 2005-04-28 2010-05-19 科斯生命科学公司 Breath actuated inhaler
CN105597199A (en) * 2014-09-18 2016-05-25 郑则广 Individual inhalation device ensuring thorough inhalation of atomized gas into lungs
CN110652632A (en) * 2018-06-29 2020-01-07 上海英何医药包装技术有限公司 Inhalation aerosol administration device

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GB2594048B (en) * 2020-04-04 2022-12-14 Purcell Global Ltd Inhaler systems

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CN100406077C (en) * 2000-03-18 2008-07-30 阿斯特拉曾尼卡有限公司 Inhaler
CN101193676B (en) * 2005-04-28 2010-05-19 科斯生命科学公司 Breath actuated inhaler
CN105597199A (en) * 2014-09-18 2016-05-25 郑则广 Individual inhalation device ensuring thorough inhalation of atomized gas into lungs
CN110652632A (en) * 2018-06-29 2020-01-07 上海英何医药包装技术有限公司 Inhalation aerosol administration device

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GB9705387D0 (en) 1997-04-30
CA2283936A1 (en) 1998-09-24
GB2323040A (en) 1998-09-16
WO1998041253A1 (en) 1998-09-24
JP2001516243A (en) 2001-09-25
EP0969890A1 (en) 2000-01-12

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