CN1245408A - Ultrasound scanning - Google Patents

Ultrasound scanning Download PDF

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Publication number
CN1245408A
CN1245408A CN97181575.5A CN97181575A CN1245408A CN 1245408 A CN1245408 A CN 1245408A CN 97181575 A CN97181575 A CN 97181575A CN 1245408 A CN1245408 A CN 1245408A
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signal
identification
biological tissue
organizational structure
ultrasonography device
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G·哈特
R·I·基特尼
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Imperial College of Science Technology and Medicine
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Imperial College of Science Technology and Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023Details of receivers
    • G01S7/52036Details of receivers using analysis of echo signal for target characterisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52053Display arrangements
    • G01S7/52057Cathode ray tube displays
    • G01S7/52071Multicolour displays; using colour coding; Optimising colour or information content in displays, e.g. parametric imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88Sonar systems specially adapted for specific applications
    • G01S15/89Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8979Combined Doppler and pulse-echo imaging systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023Details of receivers
    • G01S7/52025Details of receivers for pulse systems
    • G01S7/52026Extracting wanted echo signals

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Remote Sensing (AREA)
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  • General Physics & Mathematics (AREA)
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  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Radiology & Medical Imaging (AREA)
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Abstract

An ultrasound scanning technique for biological tissue examines the radio frequency signals derived from reflected ultrasonic energy to identify signal parameters indicative of particular tissue histology. Such identification is then used to produce a histological image of the biological tissue. The technique is particularly useful in the examination of blood vessels to identify different types of plaque within the vessel wall. Lipid plaques produce relatively low levels of reflection. Calcified plaques produce high levels of regular reflection. Fibrous plaques may be identified as a highly homogeneous thickened wall area that does not show the characteristics of a lipid plaque. A homogeneity value for the radio frequency signal is calculated for all areas not identified as lipid plaques or calcified plaques and then this homogeneity value is mapped to a colour that is displayed within the histological image.

Description

Ultrasonic scanning
The present invention relates to the ultrasonic scanning field, more specifically, the present invention relates to the ultrasonic scanning of the biological tissue of medical application.
The ultrasonic scanning of biological tissue is a widely used diagnostic method in the medical science.Ultrasonic scanning is AT, fast, to the very low danger of person under inspection's tool, and compare with other scanning technique need be lower the equipment cost.The example that ultrasonic scanning is used is to check blood vessel wall, so that detect tremulous pulse and determine its performance.
Defective blood vessel is the main cause of disease.Blood flow is obstructed, and defective blood vessel wall can discharge or cause the generation of thromboembolism, it elsewhere total blockage to the blood supply of some human organ and cause clinical problem as apoplexy.Ultrasonic scanning can be used to produce blood vessel laterally or the gray scale image of longitudinal profile, so that the speckle in the identification blood vessel wall.
The gray scale image of B ultrasonic is difficult to put in order experimental result, for helpful at this point, and attempts and obtain the assessment of the more quantitative speckle order of severity, has developed the blood flow measurement technology of using ultrasonic scanning.An example of this technology is the colorful blood mapping graph that detects the blood flow rate of passing through vessel lumen with Doppler effect.If there is structure/speckle on the blood vessel wall, therefore, these have often disturbed the blood flow (for example, causing the downstream disturbances of blood flow) of uniformity, and this blood flow can also be used the Doppler technology quantitative measurement with the very fast identification of colored flow mapping graph technology.
The ultrasonic scanner of this diagnosis usefulness of confession and the existing development plan of method are mainly towards the frame rate that increases by the picture that ultrasonic scanner produced, to produce the real-time smooth mobile Fig. 2 and the demonstration of endovascular blood flow, though these effort have improved diagnosis, also there are many inherent and tangible problems in they.
Endovascular speckle can consider to be divided into several different characteristic types.First type is because the structure in the vessel lumen that fibre thickening forms in the blood vessel.The danger that fractures that this fibre thickening tool is low relatively is because they unlikely rupture (break free) or cause thrombosis.Another kind of plaque type is a kind of thickening that comprises harder and more crisp calcified regions, and there is disruptive danger slightly in this calcified regions, and on the other hand, it may cause the tissue injury of blood vessel wall again, hemorrhage and formation thrombosis.Yet the most dangerous plaque type is the fatty speckle, and the fatty speckle in the blood vessel wall that thickens is made up of the capsule of fatty tissue, and on the throne by overcoat (cover) rest of fiber.As (or other reason) fracture under stress of fruit fiber overcoat, the fat material band potential harmful consequence and is discharged in the blood flow, and the overcoat of fracture itself might cause potential thrombosis.In agglutination, clot will form around the region of fracture, described zone potential cause thrombosis or angiemphraxis.
As can be seen, the blood vessel wall that thickens can cause the speckle of the dissimilar extents of injury very different with their relevant tools own.These different extents of injury have corresponding different therapeutic outcome.Yet, use ultrasonic scanner, though can the identification blood vessel and the structure of the blood vessel wall that thickens, extremely difficult resolution is the speckle that has what type.This difficulty is especially severe between fibroid speckle and fatty speckle.
According to one aspect of the present invention, a kind of ultrasonography device that is used for biological tissue's imaging is provided, said ultrasonography device comprises:
One is used for to biological tissue's emission ultrasonic energy of desiring imaging and is used for producing from the ultrasonic energy of the reflection that received the sonac of radiofrequency signal; With
One is used for the prearranged signals parameter signal processor relatively of the organizational structure of the dissimilar biological tissue of said radiofrequency signal and expression, so that the zone of one or several different tissues structure of identification, described signal processing apparatus also are used to produce the organizational structure image of the one or more different tissues structural regions of the visual differentiation of energy.
The signal that the present invention adopts different path analysis ultrasonic scannings to produce.Identification of the present invention not only uses the radiofrequency signal from the ultrasonic energy of reflection to produce gray scale image (increasing resolution and frame rate as possible), described radiofrequency signal is included in their interior information of hiding own, by showing the characteristics of organizational structure that is scanned tissue to anatomizing of they.This is not the organizational structure image of real slide, but a kind of image that provides and indicate the texture characteristic of tissue.This organizational structure information is more valuable than any increase resolution or frame rate under many circumstances.
More specifically, radiofrequency signal can be by signal processor and prearranged signal parameter (for example, amplitude characteristic, the level feature of peak or paddy, discrete features, phase place atypical characteristic etc.) relatively, and this comparison can be one, collective and be to combine with the feature of peripheral region in some cases with the organizational structure of identification particular tissues.In above-mentioned example, the present invention can be used for normal structure, fatty speckle, the differentiation between the calcified plaque on fibroid speckle and the blood vessel wall.The present invention also can be used for the scanning to other biological tissue, for example, and mammography, liver scanning, kidney scanning etc.
The organizational structure image that produces by the present invention can show individually.Yet in a preferred embodiment of the invention, said signal processor produces the gray scale image based on the said biological tissue of said RF signal strength.Said gray scale image is topped on said organizational structure image.
By the topped organizational structure image of gray scale image each contained information can be supported each other in the explanation of confirming scanning result to diagnostic purpose.
The explanation of organizational structure image is easy to carry out in an embodiment of the present invention, the organizational structure or the homogeneous chromatic image of the color showing different tissues that wherein said organization chart as if usefulness are different.
As previously mentioned, the present invention can be used for biological tissue's inspection of number of different types.Yet the present invention is particularly suitable for being used for following system: wherein said biological tissue is at the intravital blood vessel of people, and said different tissues structural region comprises dissimilar blood vessel wall specklees.
In this vessels analysis, can find it is very easily, signal processor can be operated under following mode, and promptly the lumen area of blood vessel can be recognized by the tool signal peak is searched for said radiofrequency signal to the value of the paddy continuum under the tube chamber level threshold of being scheduled to signal peak under the predetermined tube chamber amplitude threshold in the body.
The search of said lumen area is from known point, and said known point is manual or recognize automatically in described lumen area.This identification can be used supersonic blood to detect or be undertaken by its assistance.
The method for optimizing that is used to recognize the fatty speckle be for have on the predetermined noise amplitude threshold and the signal peak under the predetermined fat speckle amplitude threshold to valley, signal peak below predetermined fat class piece level threshold and exist the continuum of fiber cover to search for one of radiofrequency signal outside the said lumen area.
Be used to recognize that the method for optimizing of calcified plaque is to be scheduled to the signal peak on the calcified plaque level threshold, the signal valley under predetermined calcified plaque valley level threshold for having, the peak value of signal is searched for one of video signal outside the said lumen area to the variation of valley is under predetermined calcified plaque amplitude of variation threshold value with the continuum of the variation signal period under predetermined calcified plaque cycle change threshold.
Another can be for diagnosing the feature that goes up the organizational structure of using to draw in an embodiment, wherein said signal processor is from being to calculate the homogeneity value of the one or more regional inner tissue homogeneity degree that is illustrated in said organizational structure image the parameter of feature changes and be controlled in the organizational structure image in one or more zones to show with said radiofrequency signal, for the homogeneity value of being calculated in the described image can the said calculating of visual expression the homogeneity value.
In a preferred embodiment, the homogeneity value is just for these zones through distinguishing not, tube chamber for example, and fatty speckle or calcified plaque are calculated.The fibroid speckle illustrates as the vascular wall area with thickening of high homogeneity value, and described zone is the zone of not doing other identification, as the tube wall speckle.
In order to recognize the organizational structure of tissue more reliably, said signal processing apparatus is divided into several signal areas to radiofrequency signal, has at least several detected signal areas can be by distinguishing biological tissue with reference to they itself with the bonded signal characteristic of signal characteristic of on every side signal area.
Should be appreciated that the present invention can append on the existing ultrasound scanner and implement, said ultrasound scanner has radiofrequency signal and control signal output interface, the radiofrequency signal that this interface allows visit to be produced by the ultrasonic energy that is reflected.Therefore, according to another aspect of the present invention, provide a kind of and be used to use the radiofrequency signal that is produced by the ultrasonic energy reflection that is reflected to make the ultrasonography device of biological tissue's imaging, said ultrasonography device comprises:
A signal processing apparatus, this device is used for the prearranged signals parameter of the organizational structure of the dissimilar biological tissue of said radiofrequency signal and expression is compared, with the zone of recognizing one or more different tissues structures be used to produce the organizational structure image of one or more different tissues structural regions that can visual differentiation.
Be to provide a kind of ultrasonic imaging method that makes biological tissue's imaging according to another aspect of the present invention, said ultrasonic imaging method comprises the steps:
To being launched ultrasonic energy by the biological tissue of imaging;
Ultrasonic energy by received reflection produces radiofrequency signal;
The prearranged signals parameter of the dissimilar biological tissue's organizational structure of said radiofrequency signal and expression is compared, to recognize the zone of one or several different tissues structure;
Produce the organizational structure image of visual differentiable one or several different tissues structural region.
The present invention describes by the mode of embodiment shown in the accompanying drawing, and accompanying drawing has:
Fig. 1 schematically shows the ultrasonic scanner that is used for vessel scanning;
Fig. 2 schematically shows because the speckle of UNKNOWN TYPE makes the blood vessel wall thickening make the gray scale image of the blood vessel of structural damage;
Fig. 3 shows the scanning pattern of Fig. 2 blood vessel of radiofrequency signal by having fatty speckle feature indication;
Fig. 4 shows radiofrequency signal as shown in Figure 3, but represents the feature of calcified plaque this moment in addition;
Fig. 5 shows radiofrequency signal as shown in Figure 3, but represents the feature of fibroid speckle this moment in addition;
Fig. 6 illustrates the operational flowchart of the signal processing of device shown in Figure 1;
Fig. 7 illustrates the strategy based on the contextual analysis of organization of the method for Fig. 6.
Ultrasonic scanner shown in Figure 1 comprises the ultrasonic scanner 2 (for example: by the Sonus 2500 of Hewlett-Packard's production) of a prior art, and it has (given frequency) ultrasonic transducer 4 that is used to study the blood vessel 6 in the patient thoracic cavity 8.Ultrasonic scanner has a radiofrequency signal delivery outlet that allows the original radio frequency signal data of each scanning line of visit.Be similar to the raster scanning input of radiotelevisor with the radiofrequency signal scanning line) be independent synchronizing signal.
Radiofrequency signal is delivered to high speed analog-digital converter 10 by amplifier stage, this transducer is signal digitalized and be temporarily stored into buffer storage before it is delivered to workstation computer 12 following of the control of the control signal of control unit, at this, exist in the RAM of workstation computer 12 as the digitized radio frequency signal data of whole signal data frame.In case this digitalized data is captured by workstation computer 12, it can be operated under the control of software there, and workstation computer plays the effect of signal processing apparatus.Should be appreciated that if necessary the function of analog-digital converter 10 and workstation computer 12 can be combined in the ultrasonic scanner 2,, perhaps can be used as independent independent device to form integrated apparatus.
Fig. 2 illustrates an example of blood vessel gray scale image.Blood vessel wall has the part 14 that thickens, tube chamber 16 can or automatically (for example be recognized by the identification of operator's (can be aided with blood flow mapping graph technology) artificially, blood flow mapping graph with the band color has the point of high blood flow rate with identification, and this information is delivered to work station).Though the thickening of blood vessel wall is one certain type speckle significantly, the type of the speckle of operator shown in recognizing without doubt is some difficulty.
Fig. 3 show blood vessel shown in Figure 2 and by blood vessel along scanning line A, B, C, D, the radiofrequency signal that E, F produce.In this case, speckle is the fatty speckle.The blood vessel wall A that does not thicken, B produce strong and irregular relatively a series of echoes in radiofrequency signal.Be corresponding to low amplitude part after this by the reflection of the blood in the tube chamber 16.The fiber cover of fatty speckle is shown as a narrow zone than strong reflection C, D.Main body at D, E fatty speckle partly has lower reflection.Decline is outer wall E, F.
In fact, tube chamber 16 can pass through the user identification, therefore, the B of radiofrequency signal, the C part also can identification.In this case, can not obscure mutually from the low amplitude reflection of tube chamber with low amplitude reflection from the fatty speckle.When remaining radiofrequency signal when scanning line scans, D, E partly have on the noise level but below predetermined fatty speckle threshold trait by the value (amplitude) of peak to paddy, and the absolute value at peak is to represent under the fatty speckle threshold value.In this case, D when can identification corresponding to fatty class piece and near corresponding part scanning line, the E part also can identification, to be formed on the neighboring region in the organizational structure image.Recognize that when the tube chamber and the fatty part of scanning line remainder can be used as calcified plaque search (as described below), stand to determine the homogeneity value then, this value equals the amassing of deviation of peak deviation and the value from the peak to paddy.This homogeneity value plots the figure corresponding to the color gamut of color palette.The fatty speckle has its oneself differentiation color in color palette.
Should be appreciated that employed threshold value is specific to the specific ultrasonic scanner that uses with putting fixed power in fatty plaque detection and other detection.Putting all scan value coefficient lookup table of deciding power for difference can store in signal processor, and scanning device is calibrated can further to improve the reliability of using threshold value.Though the absolute value of threshold value can be the particular value of scanning device and setting, and very little of the relative value of week value, therefore, they provide the organizational structure indication of favorable tissue together.Threshold value can be retrieved a signal value from question blank.
Fig. 4 removes out in region D corresponding to Fig. 3, and E comprises calcified plaque.The characteristic signal parameter of calcified plaque is strong and well-regulated echo.These features can by the search tube chamber outer have signal amplitude on given threshold value.The valley of signal is recognized to the deviation of valley and the continuum under the deviation threshold of signal in the duration under given threshold value and by peak value.These signal parameters have defined a highly well-regulated and signal significantly jointly.Recognize when such calcified plaque zone, can specify the distinct color of itself in the organizational structure image, and can from the homogeneity value is calculated, get rid of.
At last, Fig. 5 is similar to Fig. 3, and it is fibrous removing out speckle, region D, E comprises fibrous tissue, D, the E zone can not satisfy identification fatty speckle or calcified plaque both one of testing standard.Therefore, need not as these two types, to distinguish.Therefore, D, what the E zone ran into is and A B; C, D and E, F calculate the homogeneity value together, thus, in the image of organizational structure, thicken the part of the relative homogeneity of blood vessel wall that is looked at as not fatty property or calcified regions.
Fig. 6 shows the operational flowchart of signal processor.In step 18, signal processor is intercepted and captured frame data (processing of time in the past gain compensation) and is rebuild gray scale image in the signal maximum dynamic range.In step 20, user is checked the corresponding gray scale image of this frame and is recognized an intraluminal point, in step 22, signal processor spreads unchecked (flood out) lumen area and by away from identification point scanning it being designated as tube chamber, surpasses the amplitude threshold that expression reaches wall of the lumen up to signal value.Can be from beginning search corresponding to position by the distance of ultrasonic transducer identification point near the scanning line place scanning line that contains identification point.
Step 24, user is followed the trail of the outer rim of identification blood vessel by centering on blood vessel with pointing device (as mouse) in the gray scale image of rebuilding.The outermost part of identification blood vessel is fairly simple for experienced operator.The outer rim of blood vessel is used for the boundary to the calculating of the further search of structure and homogeneity value.
Step 26, but these zones profile that user determine in outside at tube chamber with the parameter of expression fatty tissue to this range searching (for example, four signal cycle zones being treated to the zone processing of the enough sizes that satisfy its feature).If find this zone, then they are marked in the radiofrequency signal data, and, do not remake further assessment.
Step 28 is finished the search to the calcification structure, and similar labelling is made in these zones.Step 30 is not the calculating of all remaining areas of tube chamber, fatty core zone or calcified regions homogeneity value of taking the logarithm in the image, and this value of calculation is used to consult the palette of color gamut then, the homogeneity value that the fibrous tissue tool is lower.
Step 32 uses that they come the display organization structured image according to fatty zone and calcified regions differentiation color mark separately, and according to the color of the homogeneity value of calculating other zone is shown.Tube chamber is cast out mass colour or is specified its color.
Fig. 7 is according to the operational flowchart that concerns key diagram 6 of single radio frequency scanning line.At first, find out signal value by search away from set point and come identification tube chamber part B, C above the position of predetermined threshold.Then this zone is designated as tube chamber, and saves further search.Search for the signal characteristic that the All Ranges except that tube chamber is carried out and finds out the fatty tissue for the second time, in this case, this signal should be in region D, finds in the E, then this zone is marked and save further search.Phase III is that all remaining not tab area are searched for calcified tissue's signal parameter.In this case, identification does not have the signal of these features.At last, all remaining areas are carried out the calculating of homogeneity value, and mark with the color value that this homogeneity is worth going out.

Claims (17)

1. ultrasonography device that is used for biological tissue's imaging, said ultrasonography device comprises:
A ultrasonic transducer is used for launching ultrasonic energy and being used for from the ultrasonic energy generation radiofrequency signal of the reflection that receives to the biological tissue of desiring imaging; With
A signal processor, be used for relatively the prearranged signals parameter of the organizational structure of the dissimilar biological tissue of said radiofrequency signal and expression, with the zone of the one or more different tissues structures of identification be used to produce the organizational structure image of one or more different tissues structural regions that can visual differentiation.
2. according to the described ultrasonography device of claim 1, wherein said signal processor produces the gray scale image based on the said biological tissue of RF signal strength, said gray scale image and the stack of said organizational structure image.
3. according to the described ultrasonography device of claim 2, wherein said organization chart likes organizational structure or the homogeneous chromatic image of representing different tissues with different colours.
4. according to claim 1,2 or 3 described ultrasonography devices, wherein said biological tissue is intravital blood vessel, and said different tissues structural region comprises normal structure and dissimilar blood vessel wall specklees.
5. according to the described ultrasonography device of claim 4, wherein the lumen area of intravital blood vessel is by peak with signal is lower than predetermined tube chamber amplitude threshold and said radiofrequency signal identification is searched in the continuum of signal peak under predetermined tube chamber level threshold to the value of paddy.
6. according to the described ultrasonography device of claim 5, wherein said lumen area search is the point of a known identification in the lumen area.
7. according to the described ultrasonography device of claim 6, wherein said known point detects identification with supersonic blood.
8. according to the described ultrasonography device of claim 4, wherein in the body tube chamber of blood vessel with the identification of supersonic blood mapping graph.
9. according to the described ultrasonography device of claim 4, wherein the tube chamber of blood vessel is by the input identification of user in the body.
10. according to the described ultrasonography device of claim 4, wherein the outward flange of blood vessel is by the input identification of user in the body.
11. according to any described ultrasonography device of claim 4-10, wherein the fatty speckle be by to have signal peak to the value of paddy on the predetermined noise magnitude threshold value and under the predetermined fatty speckle amplitude threshold, signal peak is under predetermined fatty speckle level threshold and exist the radiofrequency signal outside the continuum search tube chamber of fiber cover to come identification.
12. according to any described ultrasonography device of claim 4-11, wherein the calcified plaque zone be by to have signal peak on the predetermined calcified plaque peak level threshold value, the signal valley under the predetermined calcified plaque level threshold, signal peak searches for radiofrequency signal identification outside the tube chamber to the deviation of valley under the predetermined calcification amplitude error threshold value and the continuum of the deviation of signal duration under predetermined calcified plaque duration deviation threshold.
13. any described ultrasonography device according to claim 4-12, wherein said signal processor is the homogeneity value that the deviation from the parameter that characterizes said radiofrequency signal is calculated the one or more regional inner tissue homogeneity degree of expression organization chart elephant, and control demonstration in the organizational structure image in one or more zones, the homogeneity value that the homogeneity value of wherein being calculated can visual expression be calculated.
14., wherein know for calculating the homogeneity value in a plurality of zones of tube chamber, fatty speckle and calcified plaque for not debating according to the described ultrasonography device of claim 13.
15. any described ultrasonography device according to aforementioned claim, wherein said signal processor is divided into several signal areas to said radiofrequency signal, at least some detected signal area by with reference to they self signal characteristic in conjunction with the signal characteristic in ambient signals zone can identification biological tissue organizational structure.
16. a ultrasonography device that is used to be made by the radiofrequency signal that the ultrasonic energy that reflects produces biological tissue's imaging, said ultrasonography device comprises:
A signal processor, the prearranged signals that is used for biological tissue's organizational structure that said radiofrequency signal and expression is dissimilar is compared, with the one or more different organizational structure zones of identification be used to produce the organizational structure image of said one or more different tissues structural regions that can visual differentiation.
17. a ultrasonic imaging method that is used for biological tissue's imaging, said ultrasonic imaging method comprises the steps:
To biological tissue's emission ultrasonic energy of desiring imaging;
Produce radiofrequency signal from received reflected ultrasound energy;
Said radiofrequency signal is compared with the prearranged signals parameter of representing dissimilar biological tissues organizational structure, with the zone of the one or more different tissues structures of identification; With
Produce the organizational structure image of the one or more different tissues structural regions of the visual differentiation of energy.
CN97181575.5A 1996-11-29 1997-11-27 Ultrasound scanning Pending CN1245408A (en)

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GB9624970A GB2319841A (en) 1996-11-29 1996-11-29 Ultrasound scanning of tissue
GB9624970.1 1996-11-29

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Cited By (3)

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CN107875518A (en) * 2017-12-20 2018-04-06 深圳冲激波科技有限公司 A kind of radio frequency physiotherapy equipment and its control method
CN114631848A (en) * 2022-02-14 2022-06-17 逸超医疗科技(武汉)有限公司 Method, device and equipment for detecting tissue uniformity and storage medium

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120445A (en) * 1998-10-02 2000-09-19 Scimed Life Systems, Inc. Method and apparatus for adaptive cross-sectional area computation of IVUS objects using their statistical signatures
US6200268B1 (en) 1999-09-10 2001-03-13 The Cleveland Clinic Foundation Vascular plaque characterization
US7727153B2 (en) * 2003-04-07 2010-06-01 Sonosite, Inc. Ultrasonic blood vessel measurement apparatus and method
JP4263943B2 (en) 2003-05-07 2009-05-13 テルモ株式会社 Ultrasonic diagnostic equipment
JPWO2005034759A1 (en) * 2003-10-09 2006-12-21 財団法人大阪産業振興機構 Lumen wall tissue characterization apparatus, image processing apparatus, image processing method, and computer program
US20070129625A1 (en) * 2005-11-21 2007-06-07 Boston Scientific Scimed Systems, Inc. Systems and methods for detecting the presence of abnormalities in a medical image
JP4839446B2 (en) * 2007-02-27 2011-12-21 国立大学法人山口大学 Ultrasound diagnostic apparatus and tissue characterization program
US20100069757A1 (en) * 2007-04-27 2010-03-18 Hideki Yoshikawa Ultrasonic diagnostic apparatus
US8545412B2 (en) 2009-05-29 2013-10-01 Boston Scientific Scimed, Inc. Systems and methods for making and using image-guided intravascular and endocardial therapy systems
JP5412242B2 (en) * 2009-11-05 2014-02-12 伸治 久米 Ultrasonic tomographic image processing device
JP5886581B2 (en) * 2011-09-26 2016-03-16 公立大学法人大阪府立大学 Vascular plaque diagnostic imaging system
US10074199B2 (en) 2013-06-27 2018-09-11 Tractus Corporation Systems and methods for tissue mapping
KR102347038B1 (en) 2014-11-06 2022-01-04 삼성메디슨 주식회사 Ultra sonic apparatus and method for scanning thereof
KR102490069B1 (en) * 2015-08-18 2023-01-19 삼성메디슨 주식회사 Ultrasonic diagnostic apparatus and operating method for the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983000009A1 (en) * 1981-06-22 1983-01-06 Whiting, James, Francis Improvements in or relating to ultrasound tomography
US4858124A (en) * 1984-08-15 1989-08-15 Riverside Research Institute Method for enhancement of ultrasonic image data
US4917097A (en) * 1987-10-27 1990-04-17 Endosonics Corporation Apparatus and method for imaging small cavities
US4945478A (en) * 1987-11-06 1990-07-31 Center For Innovative Technology Noninvasive medical imaging system and method for the identification and 3-D display of atherosclerosis and the like
US5845639A (en) * 1990-08-10 1998-12-08 Board Of Regents Of The University Of Washington Optical imaging methods
US5203337A (en) * 1991-05-08 1993-04-20 Brigham And Women's Hospital, Inc. Coronary artery imaging system
US5360005A (en) * 1992-01-10 1994-11-01 Wilk Peter J Medical diagnosis device for sensing cardiac activity and blood flow
US5417215A (en) * 1994-02-04 1995-05-23 Long Island Jewish Medical Center Method of tissue characterization by ultrasound
US5535750A (en) * 1994-09-30 1996-07-16 Kabushiki Kaisha Ishikawa Seisakusho, Ltd. Method and apparatus for evaluating the progress of osteoporosis by ultrasonic signals

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102580260A (en) * 2010-12-17 2012-07-18 通用电气公司 Systems and methods for automatically identifying and segmenting different tissue types in ultrasound images
CN102580260B (en) * 2010-12-17 2016-12-21 通用电气公司 Ultrasonoscopy identifies automatically and the system and method for segmentation histological types
CN107875518A (en) * 2017-12-20 2018-04-06 深圳冲激波科技有限公司 A kind of radio frequency physiotherapy equipment and its control method
CN114631848A (en) * 2022-02-14 2022-06-17 逸超医疗科技(武汉)有限公司 Method, device and equipment for detecting tissue uniformity and storage medium
CN114631848B (en) * 2022-02-14 2024-04-05 逸超医疗科技(北京)有限公司 Method, device, equipment and storage medium for detecting tissue uniformity

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