CN1233346C - Novel medicine for treating urinary retention and preparing method thereof - Google Patents

Novel medicine for treating urinary retention and preparing method thereof Download PDF

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CN1233346C
CN1233346C CN 02116035 CN02116035A CN1233346C CN 1233346 C CN1233346 C CN 1233346C CN 02116035 CN02116035 CN 02116035 CN 02116035 A CN02116035 A CN 02116035A CN 1233346 C CN1233346 C CN 1233346C
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medicine
mountain
novel medicine
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CN1451409A (en
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唐定秀
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Abstract

The present invention relates to a novel medicine for treating uroschesis and a preparing method thereof. The novel medicine is a Chinese herbal medicine preparation prepared from Astragalus root, atractylodes macrocephala, radix codonopsitis, liquorice, Cimicifugae Rhizoma, Bupleuri Radix, angelica, phellodendron, fructus gardeniae, Dioscorea nipponica, radix linderae, lichen seed, yam and steatite as raw materials. The novel medicine has particularly obvious therapeutic effect especially on the acute uroschesis of senile prostatomegaly, and has the effects of immediate action for removing diseases after taken and no recurrence after cure on dysuria and constipation after operation, uroschesis because of vesical dysfunction caused by medicines, common frequent micturition, urgent micturition, acute prostatosis, urinary dropping and other diseases. The novel medicine has the advantages of little dosage, convenient taking and no toxic or side effect.

Description

A kind of medicine for the treatment of urine retention and preparation method thereof
The present invention relates to a kind of new drug for the treatment of urine retention, particularly relate to a kind of Chinese herbal compound preparation that old people's prostate hyperplasia acute urinary retention is had unique significant curative effect.
The invention still further relates to the preparation method of this medicine.
Before the present invention was unexposed, medical circle did not also have a kind of ideal medicament that the urine retention disease is had unique significant curative effect.Urine retention is a kind of commonly encountered diseases, easily raises difficult questions and controls.Urine retention is called " difficulty in urination " in Chinese medicine, meaning is that dysuria is " infirmity ", and drop is not " closing " down, the patient not only shows as the urine drop not down, little multiple distension, still inaccessible obstructed with stool mostly simultaneously, the patient often feels to urinate to drip and expands unbearably, stool desires to separate constantly, but being difficult to solve, also is a small amount of half congealed loose stool even solve with strength, and patient is very painful, if can not get for a long time alleviating, with threat to life safety.Because old people's physical weakness, metabolism is not prosperous, urine retention mostly occurs the old people more than 55 years old, especially with the easier burst prostate hyperplasia of male senile patient acute urinary retention, in addition, some surgery patients because of spinal injury, cause delayed ischemic neurological deficits and diet to be taken medicine and improper etc. cause easily that also the defecation obturation is obstructed.Usually, urine retention patient is in case generation nearly all is suddenly to send urology department or surgery rescue in hospital to hospital with the emergency treatment critical patient.At present, this emergency treatment disease of clinical treatment does not also have ideal specific drug, treatment processing method commonly used mainly is hot compress, bladder massage, acupuncture-moxibustion, urethral catheterization, application estrogen etc., when above all methods are invalid, then have to consider to implement bladder and makes flaccidity art or prostatectomy.Yet, implement bladder and make the flaccidity art, can not pull out for a long time because of conduit, cause infection inflammation easily, and bring great misery and inconvenience to the patient.Implement prostatectomy, for older, body constitution is relatively poor, especially urinary system infection own, renal insufficiency and cardiovascular function have obstacle person, bigger difficulty and risk are arranged, just be difficult to solve as the surgical hemostasis problem, and the postoperative sexual function obviously goes down, side effect and sequela are serious.According to " Chinese medicine information newspaper ", someone once carried out investigation statistics to 136 routine urine retention patients, at least sexual intercourse patient once weekly before the art, postoperative has the forfeiture erection function more than 2/3rds, lose sex life ability, even 1/3rd still have among the patient of erection function at this, Shang Yousan/one patient has ejaculation to penetrate the disease of urine again when orgasm.As seen, though operative treatment can be removed misery for the moment, often lose more than gain.Therefore, although the traditional Chinese medical science, ancient medical book nationality and modern Chinese medicine internal medicine to " difficulty in urination " though pathogeny, diagnosis and dialectical treatment detailed elaboration is arranged, but the effective treatment to this emergency case does not make a breakthrough always, even indivedual accidental several examples of curing but are unable to undergo the check of repetition medical practice.Existing medicine of curing urine retention remains in that pharmacodynamic feature is strong, treatment time is long, be difficult to radical cure, the high deficiency of relapse rate.
The object of the present invention is to provide a kind of to the urine retention disease, the medicine that particularly old people's prostate hyperplasia acute urinary retention is had unique significant curative effect, diseases such as this medicine is also thin to the urine retention of the inaccessible obstructed and drug-induced vesical dysfunction of various operation backs defecation and frequent micturition, urgent micturition, anxious line that various reason causes simultaneously, dribbling have all that promptly clothes take effect, As the medicine took effect, the symptoms lessened, cure the effect that is difficult to recurrence, and its consumption is little, taking convenience, have no side effect.Another object of the present invention is to provide the preparation method of this medicine.
The objective of the invention is to realize that by following technical proposals a kind of medicine for the treatment of urine retention is the medicament of being made by the following weight proportion raw material:
Water caltrop grass 10-50g Rhizoma Atractylodis Macrocephalae 10-15g SHITOUSEN 10-30g
Well-informed 6-15g week numb 6-15g mountain dish 10-25g
The red 10-30g of 10-25g Cortex Phellodendri (mountain Tu) 10-20g wood is begged on the mountain
Other its 10-20g lichens (Semen Plantaginis) 10-15g of Dioscorea nipponica Mak. Ningpo Yam Rhizome 10-20g
Rhizoma Dioscoreae Nipponicae 10-30g liquid stone 10-50g.
A kind of its excellent weight proportion of medicine for the treatment of urine retention of the present invention is:
Water caltrop grass 20g Rhizoma Atractylodis Macrocephalae 10g SHITOUSEN 15g
Well-informed 6g week numb 8g mountain dish 12g
The red 12g of 12g Cortex Phellodendri (mountain Tu) 10g wood is begged on the mountain
Other its 12g lichens (Semen Plantaginis) 10g of Dioscorea nipponica Mak. Ningpo Yam Rhizome 12g
Rhizoma Dioscoreae Nipponicae 25g liquid stone 30g.
A kind of medicine its preparation method for the treatment of urine retention of the present invention is:
A. take by weighing each raw material;
B. get that mountain dish, mountain are begged, other its three kinds of raw materials that aromatic odor is arranged, through clean, cut into slices, dry, to grind into fine powder more stand-by;
C. remaining 11 kinds of raw material is cleaned, is put in aluminium pan or the porcelain enamel barrel with clear water, after adding an amount of clean water and boiling 1 hour, after filtration, contains and gets filtrate; After decocting three filtrations so repeatedly, mix all filtrates, discard bits;
D. filtrate among the C. is put into aluminium pan and continue to decoct, until being condensed into scattered paste shape, cooling;
E. cooled magma is mixed with fine powder among the B. and mix thoroughly, make graininess, put in the textile cloth bag, seal through drying; Put into plastic film bag again, sealing; It is standby promptly to make the agent that is taken after being infused in hot water or decoction.In addition, also can be made into granule or powder preparation to be taken after being infused in boiling water.
Medicine of the present invention is pure Chinese herbal compound preparation, and taking convenience has no side effect, and it is made the agent particle appearance that is taken after being infused in hot water or decoction and is brown.Called after " leads to and closes spirit " temporarily.
Medicine of the present invention " leads to and closes spirit " instructions of taking: " lead to and close spirit " bag film is cut off taken out the agent medicated bag that is taken after being infused in hot water or decoction, put in the enamelled cup, add 300 milliliters of boiled water, soak and boiled 5-10 minute, available spoon constantly stirs the extruding medicated bag in the boiling part, fully overflows with medicinal effective ingredient in the short bag.Pour out medicinal liquid, digestion twice in kind adds 250 milliliters in boiled water at every turn again, mixes three times the digestion medicinal liquid.Decoction being taken warmly at twice, every morning, afternoon service once, and take one hour ante cibum.The present invention's medicinal " lead to and close spirit ", also can directly adopt the decoction canonical to use: it is good with medicine inspection promptly to press the medicament prescription, puts in the sand jar, soaks 10-15 minute for three bowls with warm water, decocts with slow fire, endures half an hour after boiling again, and inclining medicinal liquid.Medicinal residues discharge water two bowls again in jar, endure half an hour after boiling equally again, and inclining medicinal liquid, decoct medicinal herbs liquid with twice and mix.Decoction being taken warmly at twice, every morning, afternoon are respectively obeyed half, and take one hour ante cibum.
The present invention " logical close spirit " pharmaceutical formulation be according to motherland's Traditional Chinese medical theory in conjunction with the modern medicine scientific and technological achievement, by extensive collection folk secret folk prescription screening, optimize, and develop on the practical basis that art uses facing for many years.The generation of " difficulty in urination " mainly is that deficiency of the spleen causing weakness of QI, middle gas lose empty because the old people is worn with age, abnormal ascending-descending of QI, and bladder qi dysfunction, the heat stagnation bladder, the large intestine conduction is unable, stagnation of QI large intestine and to cause the defecation obturation obstructed.In the medicine prescription of the present invention, water caltrop grass, Rhizoma Atractylodis Macrocephalae, SHITOUSEN, well-informed invigorating the spleen and benefiting QI; Beg to nourish blood on the mountain; Mountain dish, all numb ascending the clear and descending the turbids; It is hot and suffocating that Cortex Phellodendri, Dioscorea nipponica Mak. Ningpo Yam Rhizome, Mu Danqing rush down bladder; Other its to regulate the flow of vital energy and to help water caltrop grass, Rhizoma Atractylodis Macrocephalae, SHITOUSEN promote the circulation of qi and water; Semen Plantaginis, Rhizoma Dioscoreae Nipponicae, the diuresis of liquid stone are logical to be closed.More than all medicines share, have invigorating the spleen and benefiting QI, ascending the clear and descending the turbid, promote the circulation of qi and water, rush down damp and hot, the logical effect of closing of diuresis clearly.
The present invention " logical close spirit " shows that through the clinography statistics that 60 routine urine retention patients are cured in clinical practice therapeutic effect is remarkable especially in recent years, and promptly clothes take effect, and As the medicine took effect, the symptoms lessened, and difficulty is seen recurrence.Especially better to the female patient effect.Case symptom situation: among the 60 routine patients, person's 58 examples more than 55 years old, male's 57 examples, women's 3 examples all are acute urinary retention, all with the urine drop down or the urine drop and under be cardinal symptom, and inaccessible obstructed with stool simultaneously, desire not separate, wherein 3 examples are with hematuria; Prostate hyperplasia acute urinary retention 54 examples, this wherein has 7 examples is obstructed because of causing the defecation obturation behind the various surgical operations; Chronic prostatitis, frequent micturition, urgent micturition, dribbling 2 examples; Inaccessible obstructed 1 example of the 5th compression fracture of lumbar vertebra and paraplela inferior defecation.Above case patient all obstructedly is in hospital surplus in the of ten day in hospital because of defecation is inaccessible, does not still have good by the various Therapeutic Method in Chinese and Western then looks for the inventor to go to a doctor taking " logical close spirit " treatment.The medication treatment result: among the 60 routine patients, promptly clothes take effect, and all cure, have no side effect.Wherein 3 routine women obey half pair of medicine defecation tonneau person 1 example, obey 1 pair of medicine and cure 2 examples.In all the other 57 male's cases, obey half pair of medicine defecation tonneau person 1 example, obey 1 pair of medicine 4 example, obey 2 pairs of medicine 13 examples, obey 3 pairs of medicine 21 examples, obey 4 pairs of medicine 5 examples, clothes 5-8 pays medicine 12 examples.In addition, the inventor successively treated example surplus the inaccessible obstructed patient 300 of all kinds of defecation with " logical close spirit " since 1984, wherein treated old people's prostate hyperplasia acute urinary retention 208 examples, and effective percentage reaches 98%, and cure rate reaches 94%.
The present invention " is led to and close spirit " already, and clinical application for many years proves, its therapeutic efficiency is remarkable especially to old people's prostate hyperplasia acute urinary retention especially, and it is obstructed to various operations back defecation obturation, spinal cord injury causes the urine retention and the prostate hyperplasia of delayed ischemic neurological deficits and drug-induced vesical dysfunction, chronic prostatitis, the frequent micturition that chronic cystitis causes, urgent micturition, the urine line is thin, diseases such as dribbling all have, upright clothes take effect, the effect that As the medicine took effect, the symptoms lessened, and it is little to have a consumption, taking convenience, raw material is easily got, preparation easily, have no side effect characteristics safe in utilization.General clothes 1-4 pays defecation and gets final product tonneau, and 5-10 pays defecation and recovers normal and fully recover, and serve on one month course of treatment and then can avoid urine retention to recur once more.Obviously, the present invention " is led to and is closed spirit " the treatment urine retention and significantly is better than existing similar other medicines and operative therapy thereof.
Treatment curative effect embodiment " is led to and closes spirit " in the present invention:
Example one: old * *, man, 66 years old, Qingjian River township, Xinning County, Hunan Province clear spring village peasant.Formerly urinate not freely, drench to drip and to have gone through not to the utmost more than 6 years.In April nineteen ninety,, urinate drop then not down because of the general malaise of suffering from cold, stool is inaccessible obstructed, send the county hospital emergency treatment to be admitted to hospital, be diagnosed as the loose acute urinary retention of senile prostatic, take a turn for the better through treating with Chinese medicine and western medicine and several different methods not have in 12 days, patient is very painful, when treatment was performed a surgical operation in preparation, good fortune was heard and is taken " lead to and close spirit ", has eaten one pair, just solved a small amount of urine that night, eats up Third Mate's defecation with regard to the all-pass profit.After eat one pair again and consolidated and do not have recurrence again.
Example two: Xu Dihan, man, 36 years old, room villager in the village shrouded in mist township, Xinning County, Hunan Province.Lifted tree because of going up a hill on November 15th, 1993 and slip and weigh wounded, two at that time lower limb were unable to stir any more, and suddenly sent orthopedics department branch of county institute of traditional Chinese medicine hospitalization, diagnosis on inspection, the 5th compression fracture of lumbar vertebra, the steel plate fixing operation was carried out in two paraplela inferior on the 3rd day, it is obstructed to last two wheat harvesting period defecation obturations, hospital does not feel any better with multiple Drug therapy and in conjunction with urethral catheterization during this time, and the state of an illness increases the weight of on the contrary, urine was led to come out yet afterwards, and patient is critically ill.Through taking " logical close spirit " 2 pairs, can solve urine, after serve on 6 pairs, defecation is unobstructed.
Example three: Li Qingyun, woman, 73 years old, Bao Kou township, Xinning County, Hunan Province Flos persicae villager.In April, 1993, patient's other day fear of cold discomfort, urine has puckery pain, and then little abdominal distention is urinated drop not down, and stool expansion constantly desires to separate and is difficult to solve, and send township's hospitalize not have in 7 days and separates.Through taking logical 1 pair of the spirit of closing, very fast normal urination, stool expansion disappearance.The back is taken 4 pairs for consolidating, and does not see recurrence through chasing after anti-3 years.

Claims (3)

1. medicine for the treatment of urine retention is characterized in that it is the medicament of being made by following weight proportioning raw material:
Water caltrop grass 10-50g Rhizoma Atractylodis Macrocephalae 10-15g SHITOUSEN 10-30g
Well-informed 6-15g week numb 6-15g mountain dish 10-25g
The red 10-30g of 10-25g Cortex Phellodendri 10-20g wood is begged on the mountain
Other its 10-20g Semen Plantaginis 10-15g of Dioscorea nipponica Mak. Ningpo Yam Rhizome 10-20g
Rhizoma Dioscoreae Nipponicae 10-30g liquid stone 10-50g.
2. the medicine of treatment urine retention according to claim 1, wherein the weight proportion of each raw material is:
Water caltrop grass 20g Rhizoma Atractylodis Macrocephalae 10g SHITOUSEN 15g
Well-informed 6g week numb 8g mountain dish 12 g
The red 12g of 12g Cortex Phellodendri 10g wood is begged on the mountain
Other its 12g Semen Plantaginis 10g of Dioscorea nipponica Mak. Ningpo Yam Rhizome 12g
Rhizoma Dioscoreae Nipponicae 25g liquid stone 30g.
3. the preparation method of the medicine of treatment urine retention according to claim 1 and 2 is characterized in that:
A. take by weighing each raw material;
B. get that mountain dish, mountain are begged, other its three kinds of raw materials that aromatic odor is arranged, through clean, cut into slices, dry, to grind into fine powder more stand-by;
C. remaining 11 kinds of raw material is cleaned, is put in aluminium pan or the porcelain enamel barrel with clear water, after adding an amount of clean water and boiling 1 hour, after filtration, contains and gets filtrate; After decocting three filtrations so repeatedly, mix all filtrates, discard bits;
D. filtrate among the C. is put into aluminium pan and continue to decoct, until being condensed into scattered paste shape, cooling;
E. cooled magma is mixed with fine powder among the B. and mix thoroughly, make graininess, put in the textile cloth bag, seal through drying; Put into plastic film bag again, sealing; It is standby promptly to make the agent that is taken after being infused in hot water or decoction.
CN 02116035 2002-04-21 2002-04-21 Novel medicine for treating urinary retention and preparing method thereof Expired - Fee Related CN1233346C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103690817B (en) * 2013-12-30 2015-11-04 山东新希望六和集团有限公司 Be used for the treatment of medicine of sow urine retention and preparation method thereof
CN104524225A (en) * 2015-01-22 2015-04-22 李宇花 Traditional Chinese medicine for treating kidney-deficiency type belly postoperative urinary retention

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