CN1223846A - Method and device for fixation of sensor in bodily lumen - Google Patents
Method and device for fixation of sensor in bodily lumen Download PDFInfo
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- CN1223846A CN1223846A CN 99101014 CN99101014A CN1223846A CN 1223846 A CN1223846 A CN 1223846A CN 99101014 CN99101014 CN 99101014 CN 99101014 A CN99101014 A CN 99101014A CN 1223846 A CN1223846 A CN 1223846A
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- bodily lumen
- sensor support
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Abstract
A device and method for fixation of a sensor in a bodily lumen, in which a sensor support is coupled to a fixation device, which is inserted into a bodily lumen. The fixation device is then secured within the bodily lumen, for example, by expansion or by suturing to the bodily lumen. The fixation device may be a stent or a dedicated anchoring ring having a sensor support coupled thereto. The fixation device may be inserted during an intervention procedure or during a special insertion procedure. The sensor may be remotely interrogated exterior to the bodily lumen periodically or continuously. Furthermore, the sensor may be provided with protective coatings to protect it from damage during insertion.
Description
The present invention relates generally to and a kind ofly is inserted in the bodily lumen process method and apparatus of protection pick off at the bodily lumen fixation of sensor with at pick off.
Monitor and/or write down various people physics, chemistry and or/pick off of physiologic parameters knows those of ordinary skill in the art.U.S. Patent No. 4,485,813 disclose a kind of pick off, and it can for good and all be implanted in the implantable medical apparatus such as heart pacemaker of inside of human body ad-hoc location.Certain physics and/or the physiologic parameters of its implanted main body of this sensor monitoring.Pick off can be stayed in the main body for prolonged period of time constantly to monitor the information of relevant main body.
U.S. Patent No. 4,485, a serious limitation of 813 disclosed pick offs is, owing to requiring to be placed in medical apparatus such as the heart pacemaker etc. and to be difficult to the independent stationary pick off to pick off, so its implantable possible position is limited.Sensing station and fixed limitation have limited the serviceability that pick off is used at inner chamber.
Be used to monitor that the pick off of intracavity parameter is by the extremely sensitive extremely thin film of mechanical pressure is made.So just produced a very big danger, promptly pick off is damaged in insertion and position fixing process.Damaging pick off can cause the sensor performance variation maybe can not operate.For example, if the film of pick off breaks during insertion, pick off will become and can not operate.Because these and the relevant danger of insertion pick off process if pick off is damaged or destroys during insertion, will cause high cost and titanic peril.Therefore, also need a kind of apparatus and method of in insertion and fixation procedure, protecting pick off.
Therefore, the purpose of this invention is to provide a kind of method and apparatus at the bodily lumen fixation of sensor.By using this method and apparatus, can be fixed on bodily lumen to the distant pick off of examining.This pick off can be used for record and/or monitor physiological parameter for example such as flow stream pressure and speed and biochemical parameter such as intracavity liquid in the parameters such as level of gas and biochemical substances.
Present supervision to the intracavity condition requires intervention (intervention) to a certain degree, and the relative risk of desired intervention has limited the frequent use to this supervision.Therefore, the invention provides a kind of sensor device, it can or be implanted in the chamber temporarily or for good and all, and can be from the outside, and for example body surface at any time carries out distant examining, without any intervening or the physics conflict.
The invention provides a kind of method and apparatus of on specific hope of intracavity and/or preferred location, fixing this pick off.This fixing can in officely what is the need for of pick off finished or independently finished by catheterization in the time of will carrying out surgical operation.Further, pick off can be connected on the prosthetic device, and as the suture of bypass, aneurysm repair device, graft be film etc. fixedly, or is installed on the fixture of its oneself special use.
Pick off can be fixed on intracavity by many methods, comprise and make pick off be attached directly to suitable position, for example, by making on the pick off just like around its peripheral hole and in surgical procedures, make on the suture of pick off attached to bypass, or by using the surgery bonding agent.Also can use support and support (Any shape and size) to make pick off be positioned at intracavity, support and support can be prosthetic device such as graft fixedly film or aneurysmal correcting unit a part or combine with it, this prosthetic device is held in sensor clip on its next door or near the correct position.In addition, can use isolated plant such as anchor ring to make pick off be fixed on intracavity, anchor ring can pass through, and for example, uses the conduit balloon expansion to remain in the chamber and also fixes in position.Anchor ring not necessarily must be circular, can be that ellipse or any other meet the shape of the position of putting most.In addition, anchor ring can have a support that separates or support in order to clamp pick off.This support or support can be Any shape and size, comprise for example circle, square, rectangle, rhombus, have or do not have linear crooked or the curve-like end, and can to make only be a limit or a solid material.
A plurality of pick offs can be attached on a support or a plurality of support, for example, lay respectively at fixedly two pick offs at film two ends of graft, or in two two connections of pick off attached to the bypass section, for example, a pick off is positioned at the inlet of aneurysm cover, and another outside that is positioned at cover is to monitor cover possible seepage on every side.In addition, pick off can have a plurality of prosthetic devices or isolated plant is supported it at intracavity, and band or belt supporting frame not for example, are supported in two pick offs between anchor ring.
Pick off can link to each other by the support support or with support, for example, a groove shape or nick shaped depression is provided on pick off, make the part of support can be inserted in the depression, perhaps the shape of pick off can be made and make its part, for example, the lip shape extends or is outstanding, reach above the size of loader with by it in this place support.In addition, pick off can by for example welding and/or bonding or any above other combination of method attached on the support.
After pick off is fixed on intracavity in for example intervention such as the implantation of aneurysm device, PTCA, crown by-pass operation etc., just periodically monitoring sensor to follow the tracks of any one in the quantity of parameters or to estimate the effectiveness of the operation of finishing.For example, can the timing supervision pick off estimating the long-term progress or the degeneration of rectification effect, and the development of disease related symptom.
Can implant and can monitor individually or simultaneously that a plurality of pick offs are to obtain along chamber and the gradient of passing prosthetic device or cross section.This pick off can be fixed on many positions of intracavity, for example, is fixed on by with or without the fixing both sides of the wound of the PYCA treatment of film of graft, and the both sides in the bypass cross section, and aneurysm repair device forward and backward or on every side, or the like.
The present invention also provides the apparatus and method of protection pick off in the pick off insertion process.For protect during insertion pick off and insert or position fixing process in eliminate infringement or destroy the danger of pick off, pick off can be coated with last layer can be in aqueous solution dissolved protective layer, protective layer transducer arrangements behind health immediately or very fast disappearance.The material that uses, the thickness and the hardness of coating can change, and for example, depend on the position of pick off, the form of pick off, the protection level of pursuit and the dissolution rate of hope.
Make fixture and can at first use for example a thin corrosion resistant plate metal or some other materials, make the plane of a fixture desired form as any metal, nonmetal or bioabsorbable material by following manufacturing.Can make the plane pattern by any suitable technology, as pattern is etched on the sheetmetal, with very thin cut, or with any other technology.
In case the material well cutting just makes its distortion, joined in its edge.For making fixture, flat metal is rolled up to the edge joined with the planar metal pattern.Support the part of pick off can be arranged in, can stretch out perpendicular to the cross section of the ring that forms, or the ring that otherwise forms from fixture stretches out along on the circumferencial direction of fixture.The place of joining in the edge is bonded together, for example can be by welding.Then, the polishing fixture is perhaps with mechanical means or use electrochemical method.
The present invention will obtain understanding more completely and understanding from following and the bonded detailed description of drawing.Wherein:
Figure 1A is depicted as the sketch map of first kind of sensor fastening device according to the preferred embodiment of the invention.
Figure 1B is depicted as according to the preferred embodiment of the present invention fixedly graphic extension of the method for Figure 1A pick off in the chamber.
Fig. 2 A and 2B represented before second kind of sensor fastening device expands according to the preferred embodiment of the invention respectively and expand after graphic extension.
Fig. 3 A and 3B have represented before the third sensor fastening device expansion according to the preferred embodiment of the invention respectively and the graphic extension after the expansion.
Figure 4 shows that and use the third fixture shown in Fig. 3 A and the 3B according to the preferred embodiment of the invention in the second method of intracavity fixation of sensor.
Figure 5 shows that the graphic extension of the template that is used for etch figures(s) 3A and 3B fixture plane pattern according to the preferred embodiment of the invention.
Figure 6 shows that the graphic extension of the template that is used for etch figures(s) 2A and 2B fixture plane pattern according to the preferred embodiment of the invention.
Figure 7 shows that the 4th kind of sensor fastening device before expanding according to the preferred embodiment of the invention.
Figure 8 shows that the graphic extension of the template that is used for etch figures(s) 7 fixture plane patterns according to the preferred embodiment of the invention.
Fig. 9 A and 9B are depicted as the cross section enlarged side view of the line that Fig. 3 sensor support of two different preferred embodiments according to the present invention forms along an a ' to a '.
With reference now to Figure 1A and 1B,, Figure 1A and 1B have represented first kind of sensor fastening device and first kind of pick off fixing means according to the preferred embodiment of the invention respectively.
In Figure 1A, shown in pick off have two at its periphery and be used for attached to the hole on the intracavity suture 3.Among Figure 1B, be depicted as the coronary artery 5 that begins and have an obturation 9 from aorta 7.Bypass 11 is connected between the point 15 of aortal point 13 and inaccessible 9 back.Pick off 1 or be positioned at proximal port 17 or be positioned at the proximal part of bypass 19.As an alternative, pick off 1 can be positioned at far distance port 21, is positioned at far distance port distal portions 23, or is positioned at the distal portions 25 behind the far distance port.Can use a lot of pick offs, can the above-mentioned position of combination in any to place pick off or to place it in the position of any other hope.Pick off 1 uses two holes that are used for adhering on suture 3 to fix in position.As an alternative, pick off 1 can use surgery bonding agent or surgery shackle to be fixed on suitable position.
With reference now to Fig. 2 A and 2B,, Fig. 2 A and 2B have represented before the expansion according to the preferred embodiment of the invention respectively and second kind of sensor fastening device after the expansion.
In Fig. 2 A, shown in non-expansion state graft fixedly film 30 have first sensor and support 32 and one second sensor support 34.As an alternative, graft fixedly film 30 can have only one to support or have plural sensor support.For example, can support one the 3rd sensor support of opposite placement of 32 at first sensor.In Fig. 2 B, be depicted as Fig. 2 A graft fixedly film 30 be in its swelling state.Expansion can be passed through, and for example, ballon catheter insertion or other method realize.For at the intracavity fixation of sensor, graft fixedly film 30 is placed on it on the position that any use graft is fixedly placed in the medical care precess of film usually.Before the expansion, at graft before or after fixedly film 30 is inserted into the chamber, pick off be placed on first sensor support within 32 and/or second sensor support 34, on or adhere on it.Then or graft fixedly film 30 expand, perhaps be inserted into intracavity and expand again.By each pick off is placed on its respective sensor support within or on or attached to the additional step on supporting, can use same procedure at the fixing big quantity sensor of intracavity.
With reference now to Fig. 3 A and 3B,, Fig. 3 A and 3B have represented before the expansion according to the preferred embodiment of the invention respectively and the third sensor fastening device after the expansion.
In Fig. 3 A, shown in be in anchor ring 42 forms of non-expansion state fixture 40 combine with sensor support 44.Fixture 40 can constitute with the extensible material of not returning its original-shape after any expansion automatically.Anchor ring 42 is made of a large amount of elliptic cross-sections 46, and elliptic cross-section 46 connects to form a ring at the intermediate phase of its long part 48.Sensor support 44 is connected with one of elliptic cross-section 46 on short part 49, and vertical with the cross section of the anchor ring 42 that forms circular flat.Sensor support 44 is rhombohedral, but can be any shape of wanting.In addition, can there be many sensor support to be connected on the anchor ring 42.As an alternative, anchor ring 42 can be made of the sine curve ring, and one or more sensor support are attached on the crest, because of it does not play any supporting role to the chamber.
Fig. 3 B is depicted as the fixture 40 of Fig. 3 A that is in swelling state.For at the intracavity fixation of sensor, fixture 40 for example is positioned at intracavity in intervention, and inserts or some other method expands by for example ballon catheter.Before expansion, before or after fixture 40 was inserted into the chamber, pick off was placed within the sensor support 40, on or adhere on it.By each pick off is placed on its respective sensor support within or on or attached to the additional step on supporting, can use same procedure at the fixing big quantity sensor of intracavity.
With reference now to Fig. 4,, is depicted as and uses the third fixture shown in Fig. 3 A and the 3B according to the preferred embodiment of the invention in the second method of intracavity fixation of sensor.Shown in Figure 1B, start from aorta 7 and have inaccessible 9 coronary artery 5 having a bypass 11, bypass 11 is connected between the point 15 of aorta point 13 and inaccessible 9 back.Be placed on the proximal part of bypass 19, the distal portions 23 before the far distance port 21, far distance port, or the distal portions behind the far distance port 25 by the pick off 50 that supports with the bonded sensor support 44 of the anchor ring 42 of Fig. 3 A and 3B.Can use a lot of pick offs, can the above-mentioned position of combination in any with place pick off or place it in any other other can use anchor ring the position.Ballon catheter insertion expansion is fixing goes up pick off 50 in position by using.
With reference now to Fig. 5,, is depicted as the graphic extension of the template that is used for etch figures(s) 3A and 3B fixture plane pattern according to the preferred embodiment of the invention.Set up the template 52 that is used for etching fixture plane pattern.Etching pattern on a foil or other extensible material then.Use for example thin laser that the plane pattern is cut down from sheet metal then.Polish the plane pattern that scales off then and curve ring-type (or other shape). Point 54 and 56 is depicted as the plane pattern and passes through for example position of solder joints in its crooked back.Welding has produced an anchor ring.Sensor support 58 is positioned near the mid point of template 52, but also can be positioned at any other position as an alternative.In addition, also a plurality of sensor support can be arranged, for example be positioned at the both sides of fixture pattern.
With reference now to Fig. 6,, is depicted as the graphic extension of the template that is used for etch figures(s) 2A and 2B fixture plane pattern according to the preferred embodiment of the invention.Set up and be used for the fixedly template 60 of membrane plane pattern of etching graft.Etching plane pattern on a foil or other extensible material then.Use for example thin laser that the plane pattern is cut down from sheet metal then.Polish the plane pattern that scales off then and curve ring-type (or other shape) and after bending, pass through for example solder joints.Sensor support 62 is positioned near the mid point of template 60, but also can be positioned at any other position as an alternative.In addition, also a plurality of sensor support can be arranged, for example be positioned at the both sides of fixture pattern.
With reference now to Fig. 7,, is depicted as the 4th kind of sensor fastening device before expanding according to the preferred embodiment of the invention.The fixture 70 that is in two anchor ring forms of non-expansion state comprises 72 and one second rings 74 of one first ring, and sensor support 76 is positioned between two rings 72,74.Fixture 70 can constitute with the extensible material of not recovering its original-shape after any expansion automatically.Fixture 70 is made of the joint 78 that interconnects in a large number, to form two rings 72,74.One of joint 78 of sensor support 76 and each anchor ring 72,74 links to each other and is positioned between two rings 72,74, and joint 78 forms the cross section of the ring 72,74 of planar annular perpendicular to each.Sensor support is rhombohedral, but can be any desirable shape.In addition, a plurality of sensor support can be arranged attached on the fixture 70.As an alternative, fixture 70 can be made of two single sine curve rings, and one or more sensor support are attached on the crest, because ring does not play any supporting role to the chamber.As an alternative, fixture 70 can by two graftes fixedly film constitute, each graft fixedly film is positioned at a side of sensor support, or has a plurality of sensor support attached thereto.
With reference now to Fig. 8,, is depicted as the graphic extension of the template that is used for etch figures(s) 7 fixture plane patterns according to the preferred embodiment of the invention.Set up the template 80 that is used for etching fixture plane pattern.Etching pattern on a foil or other extensible material then.Use for example thin laser that the plane pattern is cut down from sheet metal then.Polish the plane pattern that scales off then and curve ring-type (or other shape). Point 82 and 83 and point 84 and 85 be depicted as the plane pattern in its crooked back by for example each position of solder joints.Welding has produced two anchor rings.Sensor support 87 is positioned near the mid point of template 80, but also can be positioned at any other position as an alternative.In addition, also a plurality of sensor support can be arranged, for example be positioned at the both sides of fixture pattern.
With reference now to Fig. 9 A and 9B,, be depicted as the cross section enlarged side view of Fig. 3 A sensor support line of formation along an a ' to a '.Shown in Fig. 9 A, at two peripheral parts of pick off 92 by for example using the wire saw cutting, use etching, use grooves 90 of formation such as cut, then pick off 92 is inserted in the sensor support 44, make two parts of sensor support 44 be arranged in groove 90, for pick off 92 provides support.As an alternative, do not use groove, can form two breach on the periphery of pick off 92, two parts of sensor support 44 are arranged in breach.
Shown in Fig. 9 B, pick off 94 forms a lip 96 around its upper limb 98.Pick off 4 can change into along its upper limb 98 has one or more projections.As an alternative, lip or projection can be positioned at bottom or any other position of pick off.Pick off 94 is connected on the sensor support 44 by methods such as for example bonding, melting welding, scolding tin welding, and flange 96 or projection are connected on the edge or a part of sensor support.As an alternative, pick off 94 can be positioned on the sensor support 44 and by flange 96 or projection and support.
Because what be used to monitor has a sensitivity to the pick off of the highstrung very thin films of mechanical pressure, can not be damaged in layout and/or destroy to protect them in lid layer coating on the pick off.Coating can be made with the material of water-soluble solvent, should be after arranging pick off immediately or very fast dissolving.Material, the thickness of coating and the hardness of coating used depend on sensing station, forms of sensor and various other factors to a great extent, comprising relevant physiology, the parameter of measurement and the layout speed of hope.
First kind of example of coating is to comprise the syrupy synthetic of being done by about equivalent dextrose plus saccharose of curing.Yet the ratio of dextrose plus saccharose can vary depending on the application.
Second kind of example of coating is the synthetic that comprises whole fine gtindings and be blended in hydroxypropyl emthylcellulose (Hydroxy Propyl Methyl Cellulose), hydroxy propyl cellulose (Hydroxy Propyl Cellulose) and silica sol (Colloidal SiliconeDioxide) in the water, and this synthetic is as the pill coating and at the commercial Opadry-Oy-34817 that obtains as gondola Colorcon company limited.
Other material also can be used as the protective layer of pick off.Protective layer can be made with any other material, and these materials are must be enough hard and thick protecting pick off not to be damaged during insertion, after the insertion immediately or very fast dissolving and the desire position in health be biocompatible.
Pick off can be with any methods availalbe coating of giving the object coating, comprising, for example, coating is sprayed onto on the pick off, pick off is dipped in the bath of liquid, coating is poured on or drops on the pick off, coating is coated on the pick off, or the like.In addition, the film that coating can a covering sensor or the major part or the whole sensor of pick off.
Claims (69)
1. at the device of bodily lumen fixation of sensor, comprising:
A fixture; With a sensor support that is connected on the fixture.
2. according to the device described in the claim 1, it is characterized in that fixture is a stent.
3. according to the device described in the claim 2, it is characterized in that stent has an end, sensor support is connected the end of stent.
4. according to the device described in the claim 1, it is characterized in that fixture is an aneurysm repair device.
5. according to the device described in the claim 1, it is characterized in that fixture is an anchor ring.
6. according to the device described in the claim 5, it is characterized in that anchor ring comprises that further at least one forms the material of parameter and be arranged to as at least one vertical sine curve shape in plane with the formation of anchor ring cross section.
7. according to the device described in the claim 6, it is characterized in that sensor support is connected on the sinusoidal crest of anchor ring.
8. according to the device described in the claim 5, it is characterized in that anchor ring further comprises many ellipses, each ellipse has the part of a long part and a weak point and interconnects about long mid point partly.
9. the device described in according to Claim 8 is characterized in that, the ellipse of sensor support and anchor ring links together about short part mid point.
10. according to the device described in the claim 1, it is characterized in that fixture comprises at least one first anchor ring and second anchor ring, sensor support is connected between first anchor ring and one second anchor ring.
11. the device according to described in the claim 1 is characterized in that, fixture comprises the fixedly fixing film of film and one second graft of at least one first graft, and sensor support is connected first graft fixedly film and second graft fixedly between the film.
12. the device according to described in the claim 1 is characterized in that, sensor support comprises that at least being positioned at the separated first sensor of intracavity supports and one second sensor support.
13. according to the device described in the claim 12, it is characterized in that, fixture has one first end and one second end, and first sensor props up near first end that support integral is connected fixture, and second sensor support is connected near second end of fixture basically.
14. the device according to described in the claim 1 is characterized in that, fixture is expandable.
15. the device according to described in the claim 1 is characterized in that, pick off has a nick shaped depression at least on its periphery, and at least a portion sensor support is arranged in this at least one nick shaped depression.
16. the device according to described in the claim 1 is characterized in that, pick off has a groove depression on its peripheral at least a portion, and at least a portion sensor support is arranged in this groove depression.
17. the device according to described in the claim 1 is characterized in that, pick off has a lip shape in its peripheral part at least and protrudes, and the part protruded of lip shape reaches sensor support outside the part of the inside at least.
18. the device according to described in the claim 1 is characterized in that, pick off has at least one and is positioned at its peripheral ledge, and at least a portion of the ledge of at least one reaches sensor support outside the part of the inside.
19. the device at the bodily lumen fixation of sensor is characterized in that, comprising:
A formation has the fixture of the periphery that can distinguish width, and this fixture has one first end and one second end;
At least one sensor stand is connected first end of fixture and extends away from the direction of second end with peripheral parallel edge substantially, it is characterized in that pick off is supported by sensor stand.
20. the device at the bodily lumen fixation of sensor is characterized in that, comprises that has a pick off that passes hole wherein at least.
21. the device at the bodily lumen fixation of sensor is characterized in that, comprises a pick off with an edge, this edge comprises at least two holes of passing wherein.
22. the device according to described in the claim 21 is characterized in that, each hole is positioned at the not homonymy at edge.
23. the device according to described in the claim 21 is characterized in that, each hole and another one hole approximately are equidistant.
24. the method at the bodily lumen fixation of sensor is characterized in that, comprises the steps:
Pick off is placed on the sensor support that is connected on the fixture;
Fixture is inserted into bodily lumen;
Fixing fixture in bodily lumen.
25. the method at the bodily lumen fixation of sensor is characterized in that, comprises the steps:
Pick off is placed in the sensor support that is connected on the fixture;
Fixture is inserted into bodily lumen;
Fixing fixture in bodily lumen.
26. the method according to described in the claim 24 is characterized in that, fixture is a stent.
27. the method according to described in the claim 24 is characterized in that, fixture is an aneurysm repair device.
28. the method according to described in the claim 24 is characterized in that, fixture is an anchor ring.
29. the method according to described in the claim 24 is characterized in that, further comprises pick off is connected step on the sensor support.
30. the method according to described in the claim 29 is characterized in that, connects to comprise pick off is bonded on the sensor support.
31. the method according to described in the claim 29 is characterized in that, connects to comprise pick off is welded on the sensor support.
32. the method according to described in the claim 25 is characterized in that, further comprises pick off is connected step on the sensor support.
33. the method according to described in the claim 32 is characterized in that, connects to comprise the part of sensor support at least is placed at least one groove depression of pick off.
34. the method according to described in the claim 32 is characterized in that, connects to comprise that at least one nick shaped that the part of sensor support at least is placed on pick off caves in.
35. the method according to described in the claim 24 is characterized in that insertion is finished in intervention.
36. the method according to described in the claim 24 is characterized in that, fixedly finishes by fixture is expanded.
37. the method according to described in the claim 36 is characterized in that, expansion is inserted by ballon catheter and is finished.
38. the method at the bodily lumen fixation of sensor is characterized in that, comprises the steps:
Pick off is inserted into bodily lumen;
The part of pick off and bodily lumen is coupled together.
39. the method according to described in the claim 38 is characterized in that, uses suture that the part of pick off and bodily lumen is coupled together.
40. the method according to described in the claim 38 is characterized in that, uses bonding agent that the part of pick off and bodily lumen is coupled together.
41. be used to be configured in the method for the device of bodily lumen fixation of sensor, it is characterized in that, comprise the steps:
Make template;
The plane pattern of fixture and sensor support is etched on the block of material, and the plane pattern of fixture has one first end and one second end;
First end of fixture plane pattern and second end are coupled together.
42. the method according to described in the claim 41 is characterized in that, fixture is a fixedly film of a graft.
43. the method according to described in the claim 41 is characterized in that, material is a metal sheet.
44. the method according to described in the claim 41 is characterized in that, material is a rustless steel.
45. the method according to described in the claim 41 is characterized in that, material is a bioabsorbable material.
46. the method according to described in the claim 41 is characterized in that, first end of plane pattern and second end are by being welded to connect.
47. be used to be configured in the method for the device of bodily lumen fixation of sensor, it is characterized in that, comprise the steps:
Use laser that the plane pattern of fixture and sensor support is cut down from a block of material, the plane pattern of fixture has one first end and one second end;
First end of fixture plane pattern and second end are coupled together.
48. be used for monitoring from afar the method for at least one physiological parameter of bodily lumen, it is characterized in that, comprise the steps:
At least one pick off that can monitor from afar is fixed on bodily lumen;
Outside bodily lumen, carry out inquiring in the face of this at least one pick off.
49. the method according to described in the claim 48 is characterized in that, at least one pick off uses the fixture with sensor support to be fixed in the bodily lumen.
50., it is characterized in that fixture is a stent according to the method described in the claim 49.
51. the method according to described in the claim 49 is characterized in that, fixture is an anchor ring.
52. the method according to described in the claim 48 is characterized in that, inquiring is regularly carried out.
53. the method according to described in the claim 48 is characterized in that, inquiring is carried out continuously.
54. the method according to described in the claim 48 is characterized in that inquiring is carried out from body surface.
55. the method at the bodily lumen fixation of sensor is characterized in that, comprises the steps:
Solvable protective layer is coated on the pick off;
Pick off is put into the sensor support that is connected with fixture;
Fixture is inserted in the bodily lumen;
Fixture is fixed in the bodily lumen.
56. the method according to described in the claim 55 is characterized in that, protective layer is a hard conating.
57. the method according to described in the claim 55 is characterized in that protective layer comprises dextrose plus saccharose.
58. the method according to described in the claim 57 is characterized in that, the dextrose plus saccharose ratio is approximately equal.
59. the method according to described in the claim 55 is characterized in that, protective layer comprises the synthetic and the water of hydroxypropyl emthylcellulose, hydroxy propyl cellulose and the silica sol of fine gtinding.
60. the method according to described in the claim 55 is characterized in that, protective layer water soluble solution.
61. the method according to described in the claim 55 is characterized in that, protective layer is dissolving fast after insertion.
62. the method according to described in the claim 55 is characterized in that protective layer is sprayed onto on the pick off.
63. the method according to described in the claim 55 is characterized in that, protective layer obtains by the dipping pick off.
64. the method according to described in the claim 55 is characterized in that protective layer is coated on the pick off.
65. being inserted in the protective layer of the pick off of bodily lumen comprises:
Glucose;
And sucrose, it is characterized in that the dextrose plus saccharose ratio is approximately equal.
66. being inserted in the protective layer of the pick off of bodily lumen comprises:
The hydroxypropyl emthylcellulose of fine gtinding;
The hydroxy propyl cellulose of fine gtinding;
The silica sol of fine gtinding;
And water.
But 67. the method that the pick off of protection remote monitoring is not damaged in being inserted into and being fixed on the bodily lumen process; comprise solvable protective layer is added in step on the pick off; it is characterized in that, inserting and fixing back protective layer dissolving to allow the operate as normal of pick off.
68. according to the method described in the claim 66, solvable protective layer further comprises dextrose plus saccharose, wherein, the dextrose plus saccharose ratio is approximately equal.
69. the method according to described in the claim 66 is characterized in that, solvable protective layer further comprises hydroxypropyl emthylcellulose, hydroxy propyl cellulose and the silica sol synthetic and the water of fine gtinding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99101014 CN1223846A (en) | 1998-01-08 | 1999-01-07 | Method and device for fixation of sensor in bodily lumen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/004,420 | 1998-01-08 | ||
| CN 99101014 CN1223846A (en) | 1998-01-08 | 1999-01-07 | Method and device for fixation of sensor in bodily lumen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1223846A true CN1223846A (en) | 1999-07-28 |
Family
ID=5270257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99101014 Pending CN1223846A (en) | 1998-01-08 | 1999-01-07 | Method and device for fixation of sensor in bodily lumen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1223846A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103476331A (en) * | 2011-04-20 | 2013-12-25 | 美敦力瓦斯科尔勒公司 | Implantable medical sensor with a channel formed by tabs for receiving an expandable fixation member |
-
1999
- 1999-01-07 CN CN 99101014 patent/CN1223846A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103476331A (en) * | 2011-04-20 | 2013-12-25 | 美敦力瓦斯科尔勒公司 | Implantable medical sensor with a channel formed by tabs for receiving an expandable fixation member |
| CN103476331B (en) * | 2011-04-20 | 2015-08-05 | 美敦力瓦斯科尔勒公司 | With the implantable medical treatment transducer of the passage for receiving inflatable fixed component formed by lug |
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