CN1223358C - Chinese medicinal herbs preparation 'Shuzetong' for treating hydrops - Google Patents

Abstract

The present invention discloses a Chinese herbal preparation for curing oedema which has a name of Shuzetong and a preparation method thereof. The Chinese herbal preparation comprises medicinal effective ingredients of seven Chinese medicines and common origanum herb volatilizing oil extracted from the formula of the dry materials of the seven Chinese medicines according to proportion by weight: 20 shares of milkvetch root, 15 shares of hirsute shiny bugleweed herb, 10 shares of leech, 10 shares of common origanum herb, 15 shares of lalang grass rhizome, 10 shares of rhizoma phragmitis and 5 shares of pokeberry root. The present invention has the functions of activating blood circulation to dissipate blood stasis, inducing diuresis to alleviate edema and eliminating urmary protein, and has good curative effects on oedema in Chinese medicine and chronic glomerulonephritis and nephrotic syndrome in western medicine.

Description

A kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome and preparation method thereof

One, technical field:

The present invention relates to a kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome and preparation method thereof, be used for the treatment of the alleged edema disease of the traditional Chinese medical science, be equivalent to treat diseases such as the so-called chronic glomerulonephritis of modern western medicine, nephrotic syndrome.

Two, background technology:

Edema is a disease name of the traditional Chinese medical science, also is a disease symptoms of doctor trained in Western medicine simultaneously, all is to be its Clinical symptoms with edema, albuminuria as diseases such as chronic glomerulonephritis, nephrotic syndromes.The prescription of motherland's therapeutic treatment edema has with Cortex Sclerotii Poriae, Cortex Mori, CORTEX ZINGIBERIS RHIZOMAE, Pericarpium Citri Reticulatae, Pericarpium Arecae and is the WUPI YIN of prescription and is the Zhen Wu Tang, Decoction for strengthening the Spleen-Yang of prescription with Rhizoma Zingiberis Recens, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Aconiti Lateralis Preparata, Poria, its WUPI YIN is mainly used the Therapeutic Method of promoting diuresis with drugs of tasteless flavour, Zhen Wu Tang, Decoction for strengthening the Spleen-Yang mainly uses the Therapeutic Method of warming YANG to promote diuresis, this two classes medicine is treated from cause of disease utilization inducing diuresis to remove edema, for detumescence curative effect is preferably arranged, also be difficult to reach but will thoroughly effect a radical cure.Edema, albuminuria that diseases such as present western medical treatment chronic glomerulonephritis, nephrotic syndrome cause, Drug therapys such as therapy that clinical normal employing is supported to the ill and application diuretic, hormone drug, immune suppressant drug.Can only alleviate, control the symptom of edema, and the palpus long-term prescription, easily recurrence after the drug withdrawal, and drug side effect is big, and life-time service easily causes drug-induced disease.

Three, summary of the invention:

The theory that the objective of the invention is to the traditional Chinese medical science is guidance, and to kidney dissection, physiology, pathology understanding, the Therapeutic Method of utilization blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema provides a kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome in conjunction with modern medicine.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention, it is characterized in that: be with the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, Rhizoma Phragmitis, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: 5 ratio was extracted the volatile oil of its Herba Origani and the mixture of the medicinal active ingredient of the whole medicines that comprise Herba Origani that extract with water seaoning, and the escalation rate of its weight ratio is ± 3%.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention; its preparation method is: with the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, Rhizoma Phragmitis, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: 5 ratio ± 3% took by weighing; in extraction pot, at first use the volatile oil of vapor method distillation extraction Herba Origani; extract the medicinal active ingredient of the whole medicines that comprise Herba Origani then with water seaoning; separation, concentrated, spray drying; with gained volatile oil and exsiccant medicinal active ingredient mix homogeneously, granulate or tabletting then.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention, contain the Radix Astragali, the Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, along Jiang Long, the medicinal active ingredient of seven kinds of Chinese medicine mixture of Radix Phytolaccae and the volatile oil of Herba Origani, its volatile oil and medicinal effective constituent are with the Radix Astragali, the Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, along Jiang Long, Radix Phytolaccae was in dry matter weight 20: 15: 10: 10: 15: 10: the mixture of the medicinal active ingredient of the volatile oil of the Herba Origani dry matter weight 0.3～0.5% that obtains in 5 the ratio prescription and the whole medicines 10～15% that comprise Herba Origani that extract with water seaoning, the escalation rate of its weight ratio is ± 3%.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention; for taking convenience; the volatile oil produced and the mixture of medicinal active ingredient are made medicinal granule or tablet, make granule or film-making by every mixture 0.5 gram that contains volatile oil and medicinal active ingredient.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention can carry out decoction in the prescription ratio, and effect is relatively poor.If take the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, along Jiang Long, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: the Herba Origani volatile oil that 5 ratio obtains and whole mixture of the medicinal active ingredient of medicines, its dose is grams every days 9～10, divides and takes for three times.

The Chinese herbal and crude drugs preparations of treatment nephrotic syndrome of the present invention, effect with blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, subduction urine protein, observe through surplus 20 years 127 routine patient's clinical therapeutic efficacies, have significant curative effect for diseases such as the alleged edema disease of the traditional Chinese medical science and the alleged chronic glomerulonephritis of doctor trained in Western medicine, nephrotic syndromes.

The present invention cures mainly because of experiencing the wet heresy of water or because of dysfunction of the spleen in transportation, kidney, functioning of bladder are had no right and the retention of water-damp in the body that arrives.Or edema with the passing of time wrong treatment, lose the person of controlling.The water damp being a kind of YIN pathogen is easily held back yang-energy, the obstruction meridians cause that hematogenous blockage becomes the stasis of blood.The wet friendship with blood stasis of water stopped in the resistance and caused edema.Blood stasis holds in kidney, bladder dysuria then.Damp pathogen being sticky and stagnant in nature, deep, touching.So edema delay is not moved back, the time is heavy when light, outbreak repeatedly.The wet spleen that is stranded of water, hypoactivity of spleen-YANG is spiritlessness and weakness, lusterless complexion then.Dark tongue quality, fatly indentation arranged, Tai Bai or white greasy greatly.The sign that deep-thready pulse is slow or heavy string is a blood stasis, water is wet.Blood stasis, the wet friendship resistance of water are the pathologic basis of edema.

Herba Lycopi in the side: " Bencao Jingshu " meaning " Herba Lycopi's hardship can expel the heat-evil, sweet energy and blood, and acid can be gone into liver, and the logical nutrient blood of temperature is controlled extensive abdominal edema, body face extremity edema, aqueous vapor in the joint." go into liver, spleen two warps, function blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.Kind blood stasis, the wet edema of handing over resistance of water controlled.So be monarch.Herba Origani: hot, warm, flavor fragrance.Energy diffusing lung, relieving exterior syndrome, promoting diuresis to clear away damp pathogen.Go into lung, spleen two warps.Lung qi dispersing gas, the lung is concerned with QI of the whole body.Then humidifying gasifies.The easypro spleen of fragrance, spleen fortune is wet also to be changed.The Radix Astragali: sweet in the mouth, slightly warm in nature, give birth to the kind inducing diuresis to remove edema of property, QI invigorating, yang invigorating.The prosperous then blood of " qi being the governor of blood " gas is capable.The fortuneization of water liquid relies the gasification of gas, and gasifying then, water liquid does not stop in having.Yang-energy rises as day pauses out when sky fills the air dampness.Hirudo: salty, bitter, flat, the function removing blood stasis is feared the vegetation mercilessness, so go into the merit that Hirudo has the thing of blood to help the Herba Lycopi to invigorate blood circulation.The Hirudo body is deceived and is born in the water, and Gu Qishan controls the edema because of blood stasis.The reason of "The Book of Changes" " People of the same tastes and habits like to be together, and unisonance is corresponding ".Radix Phytolaccae: bitter, cold.Go into spleen, bladder two warps, its property master sedimentation, diuretic tonneau two just divides the wet merit of water that disappears under rushing down, and four medicines help the Herba Lycopi, blood circulation promoting and blood stasis dispelling, the merit of inducing diuresis to remove edema is a ministerial drug.The suffering of Herba Lycopi, the Radix Astragali is sweet, hot sweet be then gas lift of sun, Hirudo, Radix Phytolaccae, become, bitter be the moon then gas fall, the then upper-jiao resembling a sprayer often again of pungent drugs can disperse and bitter drugs can descend ascending or descending movement of vital Qi, middle Jiao is as irrigating lower-jiao resembling water passages.The defeated commentaries on classics of three warmers then water as usual is wet to stop in change is difficult.Rhizoma Imperatae, Rhizoma Phragmitis are adjuvant drug in the side, and two medicines are sweet cold, Rhizoma Imperatae inducing diuresis to remove edema purify the blood partially the stagnant heat sweet in the mouth of branch and mud diaphragm not, cold in nature and do not hinder stomach, Rhizoma Phragmitis hollow can replenishing YIN and removing heat, again can diversion descending, water is gone and the moon is not hindered, the cold temperature with Radix Astragali (processed), Hirudo of two property of medicine.

Make a general survey of full side, focus on blood circulation promoting and blood stasis dispelling, blood stasis goes then edema from disappearing.Be the method that original is asked the source, compatibility is rigorous eliminating evil and just do not hinder, diuretic and non-impairment of YIN.Simultaneously using both cold and hot drugs temperature and not dry brings out the best in each other.

Four, description of drawings:

Accompanying drawing is technological process of production figure of the present invention.

Five, the specific embodiment:

Embodiment 1: with the dried medical material Radix Astragali; the Herba Lycopi; Hirudo; Herba Origani; Rhizoma Imperatae; along Jiang Long; Radix Phytolaccae takes by weighing 20kg respectively; 15kg; 10kg; 10kg; 15kg; 10kg; 5kg; at first Herba Origani is put into extraction pot; it is stand-by to extract the about 0.04kg of volatile oil with vapor method; the reuse water seaoning is extracted the medicinal active ingredient of the whole medicines that comprise Herba Origani; separate; concentrate; spray drying; get the about 10kg of medicinal active ingredient; then gained volatile oil is sprayed into mix homogeneously in the active ingredient; make granule or be pressed into tablet by 0.5 1 of gram; test package; dose is every day three times, about each 6 or 3g.

Embodiment 2: with the dried medical material Radix Astragali; the Herba Lycopi; Hirudo; Herba Origani; Rhizoma Imperatae; along Jiang Long; Radix Phytolaccae takes by weighing 103kg respectively; 78kg; 51.5kg; 51.5kg; 78kg; 51.5kg; 25.8kg; at first Herba Origani is put into extraction pot; it is stand-by to extract the about 0.2kg of volatile oil with vapor method; the reuse water seaoning is extracted the medicinal active ingredient of the whole medicines that comprise Herba Origani; separate; concentrate; spray drying; get medicinal active ingredient 50kg; then gained volatile oil is sprayed into mix homogeneously in the medicinal active ingredient; make granule or be pressed into tablet by 0.5 1 of gram; test package; dose is every day three times, about each 6 or 3g.

Embodiment 3: with the dried medical material Radix Astragali; the Herba Lycopi; Hirudo; Herba Origani; Rhizoma Imperatae; along Jiang Long; Radix Phytolaccae takes by weighing 97kg respectively; 72.8kg; 48.5kg; 48.5kg; 72.8kg; 48.5kg; 24.2kg; at first Herba Origani is put into extraction pot; it is stand-by to extract the about 0.15kg of volatile oil with vapor method; the reuse water seaoning is extracted the medicinal active ingredient of the whole medicines that comprise Herba Origani; separate; concentrate; spray drying; get medicinal active ingredient 42.5kg; then gained volatile oil is sprayed into mix homogeneously in the medicinal active ingredient; make granule or be pressed into tablet by 0.5 1 of gram; test package; dose is every day three times, about each 6 or 3g.

Claims (4)

1, a kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome, it is characterized in that: be with the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, Rhizoma Phragmitis, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: 5 ratio was extracted the volatile oil of its Herba Origani and the mixture of the medicinal active ingredient of the whole medicines that comprise Herba Origani that extract with water seaoning, and the escalation rate of its weight ratio is ± 3%.

2, a kind of preparation method for the treatment of the Chinese herbal and crude drugs preparations of nephrotic syndrome; it is characterized in that: with the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, Rhizoma Phragmitis, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: 5 ratio ± 3% took by weighing; in extraction pot, at first use the volatile oil of vapor method distillation extraction Herba Origani; extract the medicinal active ingredient of the whole medicines that comprise Herba Origani then with water seaoning; separation, concentrated, spray drying; with gained volatile oil and exsiccant medicinal active ingredient mix homogeneously, granulate or tabletting then.

3, a kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome according to claim 1, it is characterized in that: be with the Radix Astragali, Herba Lycopi, Hirudo, Herba Origani, Rhizoma Imperatae, Rhizoma Phragmitis, Radix Phytolaccae in dry matter weight 20: 15: 10: 10: 15: 10: the mixture of the medicinal active ingredient of the volatile oil of the Herba Origani dry matter weight 0.3～0.5% that 5 ratio is obtained and the whole medicines 10～15% that comprise Herba Origani that extract with water seaoning, the escalation rate of its weight ratio was ± 3%.

4, a kind of Chinese herbal and crude drugs preparations for the treatment of nephrotic syndrome according to claim 1 is characterized in that: be granule or sheet, every mixture 0.5 gram that contains volatile oil and medicinal active ingredient.