CN1209075C - Incursion type light sound detect device - Google Patents
Incursion type light sound detect device Download PDFInfo
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- CN1209075C CN1209075C CN 02121675 CN02121675A CN1209075C CN 1209075 C CN1209075 C CN 1209075C CN 02121675 CN02121675 CN 02121675 CN 02121675 A CN02121675 A CN 02121675A CN 1209075 C CN1209075 C CN 1209075C
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- optoacoustic
- signal
- sensing apparatus
- intrusive mood
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Abstract
The present invention relates to an incursion type light sound detecting device which is inserted into a blood vessel and utilizes an ultrasonic array sensor and a laser source sensor of a laser Doppler system so as to simultaneously acquire the physiological information of the cross section image of blood vessel wall tissues, blood flow numerical value in the blood vessel, etc. The ultrasonic array sensor emits and receives an ultrasonic signal through a plurality of sensing units, a plurality of matching units are fixedly arranged at the outer circumferences of the sensing units, and an absorption unit is fixedly arranged at the inner circumferences of the sensing units. A plurality of signal windings are utilized to transfer a sensing signal produced in a way that the sensing units receive an ultrasonic signal, and the signal windings are inbuilt on the absorption unit.
Description
Technical field
The invention relates to a kind of intrusive mood optoacoustic sensing apparatus, refer to a kind of interior miniature optoacoustic sensing apparatus of cardiovascular that is applicable to the cardiac catheter operation especially.
Background technology
Press, when carrying out cardiac catheters such as coronary artery hypertrophy, arteries thromboembolism, balloon dilatation operation, the doctor must obtain in vascular wall tissue cross sectional images and the blood vessel physiologic informations such as blood flow numerical value, with convenient carrying out of performing the operation.
Traditional practice is to use intrusive mood catheter-based ultrasound wave system system (Intravascular UltrasoundSystem, IVUS), its function only separately the vessel scanning wall organize cross sectional images or measure blood flow velocity separately, and can't carry out two kinds of above-mentioned functions simultaneously.Make the doctor in operation is carried out, can't obtain instant enough information, even must substitute the conduit of difference in functionality often, cause the misery and increase operative failure rate of sufferer.
The another kind of practice is to adopt laser-Doppler blood flow examining system (Laser Doppler bloodflow meter), it is from the microvascular blood flow speed of external measurement body surface, but in the body than tissues such as depths blood vessel and heart peripheries, laser can't penetrate to arrive partly and then can't measure, and this method can't present the cross sectional images of vascular tissue.
The inventor whence originally in the spirit of positive invention, is urgently thought a kind of " intrusive mood optoacoustic sensing apparatus " that can address the above problem because of in this, and several times research experiment is eventually to the invention of finishing these good common people of suffering from.
Summary of the invention
Main purpose of the present invention is that a kind of intrusive mood optoacoustic sensing apparatus is being provided, so that can obtain physiologic informations such as vascular wall tissue cross sectional images and the interior blood flow numerical value of blood vessel simultaneously, and need not repeat to substitute the conduit of difference in functionality.
Another object of the present invention is that a kind of intrusive mood optoacoustic sensing apparatus is being provided, so that can be determined the position of blood vessel embolism by the variation of blood flow numerical value, with the irradiation dose of indirect minimizing location with X-ray.For reaching above-mentioned purpose, a kind of intrusive mood optoacoustic of the present invention sensing apparatus is to be inserted in internal blood vessel, and cooperates a laser signal source, it is characterized in that, this optoacoustic sensing apparatus mainly comprises:
A plurality of sensing cells are in order to emission and received ultrasonic signal;
A plurality of matching units are the peripheries that are fixedly arranged on these a plurality of sensing cells, to mate the impedance contrast distance of these a plurality of sensing cells and human body;
One absorptive unit is fixedly arranged in these a plurality of sensing cells and encloses, and to absorb the schottky noise that these a plurality of sensing cells produce, this absorptive unit inside is to be hollow;
A plurality of signal line group are to transmit the sensing signal that these a plurality of sensing cell emissions produce with receiving this ultrasonic signal, and these a plurality of signal line group are to be mounted in this absorptive unit; And
One optical signal sensing cell is to be positioned at this absorptive unit inside, and this optical signal sensing apparatus comprises a plurality of optical fiber;
This blood vessel optoacoustic sensing apparatus still comprises a conduit and a packaging body, and an end of this conduit is the periphery that is sheathed on these a plurality of sensing cells, and installs this packaging body in an end of this conduit;
Wherein, this laser signal source is via the optical fiber of at least one optical fiber as the emission optical signal, to deliver in this blood vessel, other a plurality of optical fiber are as the optical fiber of receiving optical signals, to receive by the optical signal that body fluid was reflected, this ultrasonic sensing device and this optical signal sensing apparatus are to control this ultrasound source and this optical signal transmitting and reception order with the sequencing contro method.
Should it be three to eight wherein as other fiber count of receiving optical signals.
Wherein the acoustic impedance of this packaging body is between human body impedance and normal saline solution, and have the ultrasonic attenuation coefficient low with have biocompatible characteristic.
Wherein this packaging body is to adopt polyurethane.
Wherein the head end of this packaging body is to be a lenticular, to increase the optically focused effect of the optical signal of being launched.
Wherein these a plurality of matching units are with sputter or are glued at the periphery of these a plurality of sensing cells.
Wherein these a plurality of sensing cells are to be piezoceramic material.
Wherein the main component of this absorptive unit is to comprise: macromolecular material, resin and metal dust.
Wherein the quantity of these a plurality of sensing cells is to be eight.
Wherein the acoustic impedance of these a plurality of matching units is between human body impedance and each and every one sensing cell of this plural number, and has the low characteristic of ultrasonic attenuation coefficient.
Because the present invention constructs novelty, can provide on the industry and utilize, and truly have the enhancement effect, so apply for patent of invention in accordance with the law.
Description of drawings
Relevant preferred embodiment of the present invention is to be that example is illustrated to insert cardiovascular.Please be with reference to the three-dimensional exploded view and the axonometric chart of Fig. 1 and Fig. 2 demonstration, it mainly comprises: ultrasound wave sensing cell 1, optical signal sensing cell 2, optical fiber 21, matching unit 3, absorptive unit 4, conduit 5, holding wire 6, packaging body 7.
The material of above-mentioned ultrasound wave sensing cell 1 is unrestricted, is preferably piezoceramic material in present embodiment.Optical signal sensing cell 2 is preferably the employing laser Doppler system in present embodiment, it has a LASER Light Source (figure does not show) and nine optical fiber 21.The material of matching unit 3 is unrestricted, is preferably a kind of material of tool acoustic impedance, and the acoustic impedance value of this tool acoustic impedance material and has the material of the low characteristic of ultrasonic attenuation coefficient between human body acoustic impedance value and ultrasound wave sensing cell 1 acoustic impedance value.The mixture of best product MetaCast 40l st (main composition is epoxy resin and silicic acid) or epoxy resin macromolecular materials such as (Epoxy1365-25) and powder such as aluminium sesquioxide and tungsten oxide for employing Ma Like company (Mereco Technologies Group).The material of absorptive unit 4 is unrestricted, is preferably by materials such as macromolecular material, resin and metal dusts to be formed in present embodiment.Packaging body 7 is to be conduit 5 most advanced and sophisticated encapsulating materials, and its acoustic impedance value is between human body impedance and normal saline solution, and have the ultrasonic attenuation coefficient low with have biocompatible characteristic.The material of packaging body 7 is unrestricted, is preferably polymer in present embodiment, and the best is polyurethane (PU).
In this example, ultrasound wave sensing cell 1 is eight, and be embedded in the periphery of absorptive unit 4 respectively, and be embedded with eight signal line 6 at eight ultrasound wave sensing cells 1 and 4 of absorptive units, a ground wire shared with each ultrasound wave sensing cell 1, so as for will each ultrasound wave sensing cell 1 emission with received ultrasonic signal after the signal that produced be sent to exterior display device.The periphery of eight ultrasound wave sensing cells 1 is also respectively with eight matching units 3 of resinoid bond, to form eight groups of ultrasonic array transducing modules, and in ultrasonic array transducing module peripheral group if the conduit 5 of a sheathed hollow, and encapsulate a transparent packaging body 7 at the tip of conduit 5, so that for emission and received ultrasonic signal, with acquisition painstaking effort tube wall tissue cross sectional images.
Because the impedance contrast of human body impedance and ultrasound wave sensing cell 1 is apart from quite big, set firmly matching unit 3 in the mode of sputter or gummed, reduce the difference of ultrasound wave sensing cell 1 and human body impedance, and can conduct the external ultrasonic signal smoothly to ultrasound wave sensing cell 1.Certainly, the quantity of ultrasound wave sensing cell 1 is unrestricted, is with eight ultrasound wave sensing cells 1 as an illustration in this example.
Fig. 3 shows that then the present invention adopts the sketch map of sequencing contro method, t1 to t4 represents 1 emission of four ultrasound wave sensing cells and the sequential that receives, t5 represents that optical fiber 21 transmits fiber-optic signal to endovascular sequential, and t6 represents that then all the other eight optical fiber receive the sequential by the optical signal of body fluid institute reflected back in the blood vessel.Wherein, about 20 microseconds of the sequential of each action, the interval after per two ultrasound wave sensing cells 1 trigger is 5 microseconds, whole work period then is about 150 microseconds.Receive sequential because of adopting this sequential control method to control each ultrasound wave sensing cell 1 with the emission of conducting optical fiber 21, and trigger the back at each ultrasound wave sensing cell 1 and reserve 5 microseconds, improve the concussion attenuation effect of ultrasound wave sensing cell 1 significantly, make conduction optical fiber 21 do not shaken the schottky noise that is produced and disturb.
By above explanation as can be known, the present invention is that the LASER Light Source sensor with ultrasonic array sensor and laser Doppler system is integrated in the intrusive mood cardiac catheter jointly, obtain physiologic information such as blood flow numerical value in vascular wall tissue cross sectional images and the blood vessel simultaneously to reach, and need not repeat to substitute the conduit of difference in functionality.And the present invention also can determine the position of blood vessel embolism via the variation of blood flow numerical value, with the irradiation dose of indirect minimizing location with X-ray.
Claims (10)
1. an intrusive mood optoacoustic sensing apparatus is to be inserted in internal blood vessel, and cooperates a laser signal source, it is characterized in that, this optoacoustic sensing apparatus mainly comprises:
A plurality of sensing cells are in order to emission and received ultrasonic signal;
A plurality of matching units are the peripheries that are fixedly arranged on these a plurality of sensing cells, to mate the impedance contrast distance of these a plurality of sensing cells and human body;
One absorptive unit is fixedly arranged in these a plurality of sensing cells and encloses, and to absorb the schottky noise that these a plurality of sensing cells produce, this absorptive unit inside is to be hollow;
A plurality of signal line group are to transmit the sensing signal that these a plurality of sensing cell emissions produce with receiving this ultrasonic signal, and these a plurality of signal line group are to be mounted in this absorptive unit; And
One optical signal sensing cell is to be positioned at this absorptive unit inside, and this optical signal sensing apparatus comprises a plurality of optical fiber;
This blood vessel optoacoustic sensing apparatus still comprises a conduit and a packaging body, and an end of this conduit is the periphery that is sheathed on these a plurality of sensing cells, and installs this packaging body in an end of this conduit;
Wherein, this laser signal source is via the optical fiber of at least one optical fiber as the emission optical signal, to deliver in this blood vessel, other a plurality of optical fiber are as the optical fiber of receiving optical signals, to receive by the optical signal that body fluid was reflected, this ultrasonic sensing device and this optical signal sensing apparatus are to control this ultrasound source and this optical signal transmitting and reception order with the sequencing contro method.
2. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that, should be three to eight as other fiber count of receiving optical signals wherein.
3. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that wherein the acoustic impedance of this packaging body is between human body impedance and normal saline solution, and have the ultrasonic attenuation coefficient low with have biocompatible characteristic.
4. intrusive mood optoacoustic sensing apparatus as claimed in claim 3 is characterized in that, wherein this packaging body is to adopt polyurethane.
5. intrusive mood optoacoustic sensing apparatus as claimed in claim 3 is characterized in that, wherein the head end of this packaging body is to be a lenticular, to increase the optically focused effect of the optical signal of being launched.
6. intrusive mood optoacoustic sensing apparatus as claimed in claim 3 is characterized in that, wherein these a plurality of matching units are with sputter or are glued at the periphery of these a plurality of sensing cells.
7. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that wherein these a plurality of sensing cells are to be piezoceramic material.
8. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that wherein the main component of this absorptive unit is to comprise: macromolecular material, resin and metal dust.
9. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that, wherein the quantity of these a plurality of sensing cells is to be eight.
10. intrusive mood optoacoustic sensing apparatus as claimed in claim 1 is characterized in that, wherein the acoustic impedance of these a plurality of matching units is between human body impedance and each and every one sensing cell of this plural number, and has the low characteristic of ultrasonic attenuation coefficient.
Priority Applications (1)
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CN 02121675 CN1209075C (en) | 2002-05-31 | 2002-05-31 | Incursion type light sound detect device |
Applications Claiming Priority (1)
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CN 02121675 CN1209075C (en) | 2002-05-31 | 2002-05-31 | Incursion type light sound detect device |
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CN1462609A CN1462609A (en) | 2003-12-24 |
CN1209075C true CN1209075C (en) | 2005-07-06 |
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CN 02121675 Expired - Fee Related CN1209075C (en) | 2002-05-31 | 2002-05-31 | Incursion type light sound detect device |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104856728B (en) * | 2009-10-29 | 2019-07-23 | 佳能株式会社 | Photo-acoustic device |
CN102596049B (en) | 2009-10-29 | 2015-04-08 | 佳能株式会社 | Photo-acoustic device |
TWI440878B (en) * | 2011-10-27 | 2014-06-11 | Ind Tech Res Inst | Ultrasound receiving module, method and system |
CN103976743A (en) * | 2014-05-27 | 2014-08-13 | 江西科技师范大学 | CMUT (Capacitive Micro-machined Ultrasonic Transducer) annular array based micro-photoacoustic transducer |
US11666224B2 (en) * | 2015-11-07 | 2023-06-06 | Purdue Research Foundation | Intraoperative optoacoustic guide apparatus and method |
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