CN1207300A - Medicine for giving up drug - Google Patents
Medicine for giving up drug Download PDFInfo
- Publication number
- CN1207300A CN1207300A CN97108170A CN97108170A CN1207300A CN 1207300 A CN1207300 A CN 1207300A CN 97108170 A CN97108170 A CN 97108170A CN 97108170 A CN97108170 A CN 97108170A CN 1207300 A CN1207300 A CN 1207300A
- Authority
- CN
- China
- Prior art keywords
- radix
- rhizoma
- group
- drug
- rhizoma corydalis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000003814 drug Substances 0.000 title claims abstract description 20
- 229940079593 drug Drugs 0.000 title abstract description 8
- 241000218176 Corydalis Species 0.000 claims abstract description 18
- 241000255791 Bombyx Species 0.000 claims description 5
- 241000756943 Codonopsis Species 0.000 claims description 5
- 241000190633 Cordyceps Species 0.000 claims description 5
- 239000000654 additive Substances 0.000 claims description 5
- 241000222336 Ganoderma Species 0.000 claims description 4
- 206010012335 Dependence Diseases 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 241000258920 Chilopoda Species 0.000 abstract 1
- 235000015489 Emblica officinalis Nutrition 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 244000277583 Terminalia catappa Species 0.000 abstract 1
- 235000011517 Terminalia chebula Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000003390 Chinese drug Substances 0.000 description 12
- 206010013754 Drug withdrawal syndrome Diseases 0.000 description 6
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 6
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 206010013654 Drug abuse Diseases 0.000 description 2
- 206010048010 Withdrawal syndrome Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 description 2
- 229960001736 buprenorphine Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 235000019788 craving Nutrition 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 206010013663 drug dependence Diseases 0.000 description 2
- 208000011117 substance-related disease Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000202807 Glycyrrhiza Species 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 241000218180 Papaveraceae Species 0.000 description 1
- 206010035039 Piloerection Diseases 0.000 description 1
- 235000016551 Potentilla erecta Nutrition 0.000 description 1
- 240000000103 Potentilla erecta Species 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010048232 Yawning Diseases 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- AXONCVPTTFHNOI-UHFFFAOYSA-N kairine Chemical compound C1=CC(O)=C2N(C)CCCC2=C1 AXONCVPTTFHNOI-UHFFFAOYSA-N 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000003533 narcotic effect Effects 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A medicine for dropping drug is prepared from 19 Chinese-medicinal materials such as myrobalan, corydalis tube, notopterygium root, dehurian angelica root, centipede, etc., and features quick taking its effect, less by-effect and no addiction.
Description
The present invention relates to a kind ofly to can be used for quitting drug abuse, the Chinese medicine of withdrawal.
In recent years, drug abuse has become the public hazards that influence people's physical and mental health, harm family, society.At present, the withdrawal method is various both at home and abroad, but also not safely, not effectively, non-addicted ideal addiction-breaking drugs.
Purpose of the present invention aims to provide a kind of rapid-action, and side effect does not gently have the Chinese medicine medicine of addicted detoxification and addiction-removing.
The Chinese medicine of China is the important wealth of the Chinese nation, and the present invention does not contain a kind of anti-additive medicament of any Western medicine and addiction Chinese medicinal ingredients just according to the pharmacology of Chinese medicine and pharmacy.
The present invention includes Fructus Chebulae, Rhizoma Corydalis, Rhizoma Corydalis Decumbentis.It is equal that Rhizoma Corydalis Decumbentis belongs to Papaveraceae, the equal same sex.The Fructus Chebulae belongs to gentleman's the orchid family.
Ratio between Fructus Chebulae, Rhizoma Corydalis, the Rhizoma Corydalis Decumbentis three is 5: 8: 8.
Fructus Chebulae, Rhizoma Corydalis, Rhizoma Corydalis Decumbentis account for 34.0-37.0% of the present invention, by weight.
Except that above-mentioned principal agent, also comprise Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, crust halberd, Rhizoma Coptidis, Radix Panacis Quinquefolii, Cordyceps, Bombyx Batryticatus, Radix Glycyrrhizae, Rhizoma Zingiberis, Fructus Jujubae, Cortex Cinnamomi, Radix Codonopsis, Radix Changii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Ganoderma.
More than each component content be: Rhizoma Et Radix Notopterygii 5.0-6.0% Radix Angelicae Dahuricae 5.0-6.0% crust halberd 1.0-2.0% Rhizoma Coptidis 2.0-3.0% Radix Panacis Quinquefolii 2.0-3.0% Cordyceps 1.0-2.0% Bombyx Batryticatus 1.5-2.5% Radix Glycyrrhizae 10-12% Rhizoma Zingiberis 0.5-1.5% Fructus Jujubae 0.8-1.5% Cortex Cinnamomi 1.5-3.0% Radix Codonopsis 4.0-5.0% Radix Changii 5.0-6.0% Radix Angelicae Sinensis 2.5-3.0% Rhizoma Chuanxiong 5.0-6.0% Ganoderma 3.0-4.0%
The present invention is familiar with according to Chinese medical discrimination, the addiction of drugs suction, and the serious disturbed dominant force of becoming homeless of the mind, the body many-side gets muddled, and forms complicated pathogenesis, causes the generation disharmony of nutrient QI with defensive QI, gastrointestinal, function of liver and spleen imbalance, heart kidney extreme misery is not handed over diseases such as deficiency of both QI and blood.With the passing of time then the thin bone of shape is upright, and the complexion clouding has the gesture of disintegrating greatly.Withdrawal symptom should belong in the malicious expectorant and accumulateing, domination of pathogen dificiency in lower-JIAO, QIYINLIANGXU, lack of preservation of spirit.Present invention focuses on to address the above problem.Rhizoma Corydalis Decumbentis, Rhizoma Corydalis, Fructus Chebulae and Semen Papaveris are of the same race to be we's principal agent with merit, and wherein Rhizoma Corydalis Decumbentis, Rhizoma Corydalis are bloodroot.Fructus Chebulae and Pericarpium Papaveris be sour in the mouth all, the astringing intestine to stop diarrhea of all astringing the lung, and the withdrawal of three medicines energy detoxicating is aided with recuperating the superficial defensive system, the body resistance strengthening and constitution consolidating, the warming the meridian blood stasis dispelling has complement each other wonderful.The prosperous then spirit of gas is shaken, and hemapodium then body is filled, so detoxification and addiction-removing is smooth, and no tired hardship.
Embodiments of the invention:
Fructus Chebulae's 255 gram Rhizoma Corydalis 411 gram Rhizoma Corydalis Decumbentiss 411 gram Rhizoma Et Radix Notopterygiis 180 grams
The Radix Angelicae Dahuricae 180 gram crust halberds 60 gram Bombyx Batryticatus 45 gram Radix Glycyrrhizaes 333 grams
Rhizoma Zingiberis 45 gram Fructus Jujubaes 30 gram Rhizoma Coptidis 90 gram Cortex Cinnamomis 90 grams
Radix Codonopsis 150 gram Radix Changiis 150 gram Radix Panacis Quinquefoliis 90 grams
Radix Angelicae Sinensis 120 gram Rhizoma Chuanxiongs 180 gram Cordycepses 60 kairine sesames 120 grams
Be clinical therapeutic efficacy of the present invention below, and compare with buprenorphine simultaneously: being admitted to hospital on August 11st, 1996 voluntarily continuously with Hunan Province narcotic house, the drug rehabilitation patient is an object of study.Therapist is included into buprenorphine treatment group or Chinese drug-treated group of the present invention at random, each each 11 example of group.With the Ninth Heaven is a course of treatment.
Treatment back 1-3 days, two groups drug craving and body reaction are the heaviest.Two groups relatively, and the physical withdrawal reaction is close, and " wanting especially to take drugs, yawn, have a stomach-ache, suffer from abdominal pain " several of Dante group is serious relatively, and difference has significance.The fourth group is total, and to crave for sense stronger than Chinese drug-treated group, and it is obviously lower than fourth group that Chinese drug-treated group was craved for total points on the 3rd day.
Two groups of physical withdrawal reactions in fourth, fifth day are close, craving for of Chinese drug-treated group this moment than a little less than the fourth group, " have a stomach-ache, stomachache, watery nasal discharge, shed tears " several of group is obviously light than the fourth group in the 4th day, " fidgety, easily fly into a rage " of group is obviously light than the fourth group in the 5th day, and craving for than the 4th day of fourth group the 5th day increases to some extent.
From treating the 6th day, the withdrawal symptom and the drug craving of Chinese drug-treated group obviously descend, and the decline of fourth group is not obvious, and the withdrawal symptom total points of Chinese drug-treated group is obviously lower than fourth group to the Ninth Heaven in treatment seven.
Treat " nauseating, regurgitation " transference cure of the 6th, seven day Chinese drug-treated group, Chinese drug-treated group " irritated, easily fly into a rage ", " covering with gooseflesh ", " ache all over the body discomfort ", " sometimes hot and sometimes cold ", " feel uneasy or be difficult to loose " " insomnia " etc. are obviously light than the fourth group, the fourth group to crave for middle group of sense heavy slightly, but total points no difference of science of statistics.
Chart 1 is that two groups of patients crave for situation of change day by day;
The drawing explanation: ◆-Ding organizes ■-Chinese drug-treated group
From chart 1,2 as seen, two groups of physical withdrawals reaction, to crave for sense generally equal Along with the passing for the treatment of time is on a declining curve. And show that Chinese drug-treated group is in therapeutic process Physical withdrawal symptom and crave for all light than the fourth group. The physical withdrawal symptom of Chinese drug-treated group always On a declining curve, substantially disappeared by the 9th day, average total points only has 4.6 fens, And the fourth group is not obvious since physical withdrawal symptom decline in the 5th day, and the 9th day average total Divide to also have 14.6 fens, two groups to crave for total points on a declining curve with therapeutic advance.
In the treatment during Chinese drug-treated group withrawal symptom and crave for always all low than fourth group, the result Show that the treatment by Chinese herbs onset is very fast, the course for the treatment of is shorter, and withrawal symptom does not have when the treatment withdrawal The characteristics such as bounce-back.
Claims (3)
1, a kind of anti-additive medicament is characterized in that including Fructus Chebulae, Rhizoma Corydalis, Rhizoma Corydalis Decumbentis, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, crust halberd, Rhizoma Coptidis, Radix Panacis Quinquefolii, Cordyceps, Bombyx Batryticatus, Radix Glycyrrhizae, Rhizoma Zingiberis, Fructus Jujubae, Cortex Cinnamomi, Radix Codonopsis, Radix Changii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Ganoderma.
2, a kind of anti-additive medicament according to claim 1 is characterized in that Fructus Chebulae, Rhizoma Corydalis, Rhizoma Corydalis Decumbentis account for 34.0-37.0% of the present invention, and the ratio between the three is 5: 8: 8, by weight.
3, a kind of anti-additive medicament according to claim 1 and 2 is characterized in that: Rhizoma Et Radix Notopterygii 5.0-6.0% Radix Angelicae Dahuricae 5.0-6.0% clings to halberd 1.0-2.0% Rhizoma Coptidis 2.0-3.0% Radix Panacis Quinquefolii 2.0-3.0% Cordyceps 1.0-2.0% Bombyx Batryticatus 1.5-2.5% Radix Glycyrrhizae 10-12% Rhizoma Zingiberis 0.5-1.5% Fructus Jujubae 0.8-1.5% Cortex Cinnamomi 1.5-3.0% Radix Codonopsis 4.0-5.0% Radix Changii 5.0-6.0% Radix Angelicae Sinensis 2.5-3.0% Rhizoma Chuanxiong 5.0-6.0% Ganoderma 3.0-4.0% by weight
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97108170A CN1060075C (en) | 1997-07-31 | 1997-07-31 | Medicine for giving up drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97108170A CN1060075C (en) | 1997-07-31 | 1997-07-31 | Medicine for giving up drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1207300A true CN1207300A (en) | 1999-02-10 |
| CN1060075C CN1060075C (en) | 2001-01-03 |
Family
ID=5170191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97108170A Expired - Fee Related CN1060075C (en) | 1997-07-31 | 1997-07-31 | Medicine for giving up drug |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1060075C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069056C (en) * | 1999-03-29 | 2001-08-01 | 苏月秋 | Pure Chinese herb medicine for stopping drugs |
| CN1090026C (en) * | 1999-11-11 | 2002-09-04 | 中国科学院西北高原生物研究所 | Novel medicine for stopping narcotic taking and preparation process thereof |
| CN107348135A (en) * | 2017-07-19 | 2017-11-17 | 安徽宏飞户外用品科技有限公司 | A kind of additive in the imitated baits for being easy to fish for |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1092315A (en) * | 1993-03-18 | 1994-09-21 | 孙先知 | A kind of external dressing ointment for wound |
| CN1098638A (en) * | 1993-08-07 | 1995-02-15 | 章贤君 | A kind of detoxicating mixture |
-
1997
- 1997-07-31 CN CN97108170A patent/CN1060075C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069056C (en) * | 1999-03-29 | 2001-08-01 | 苏月秋 | Pure Chinese herb medicine for stopping drugs |
| CN1090026C (en) * | 1999-11-11 | 2002-09-04 | 中国科学院西北高原生物研究所 | Novel medicine for stopping narcotic taking and preparation process thereof |
| CN107348135A (en) * | 2017-07-19 | 2017-11-17 | 安徽宏飞户外用品科技有限公司 | A kind of additive in the imitated baits for being easy to fish for |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1060075C (en) | 2001-01-03 |
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| Date | Code | Title | Description |
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| C10 | Entry into substantive examination | ||
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: HUNAN XUANXIA PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: YIN DALIANG Effective date: 20031210 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20031210 Address after: 410006 Hunan province Changsha hi tech Industrial Development Zone, valley base of Oak Park D1 Building 2 floor Patentee after: Pharmaceutical Co., Ltd. Hunan Hyun Xia Address before: 410007, No. 28, Xinjian West Road, Yuhua Pavilion, Hunan, Changsha Patentee before: Yin Daliang |
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| PD01 | Discharge of preservation of patent |
Date of cancellation: 20100814 Granted publication date: 20010103 |
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Date of cancellation: 20110214 Granted publication date: 20010103 |
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| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20010103 Termination date: 20130731 |