CN119708144A - 肽化合物及其治疗疾病的方法 - Google Patents

肽化合物及其治疗疾病的方法 Download PDF

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Publication number
CN119708144A
CN119708144A CN202411888874.5A CN202411888874A CN119708144A CN 119708144 A CN119708144 A CN 119708144A CN 202411888874 A CN202411888874 A CN 202411888874A CN 119708144 A CN119708144 A CN 119708144A
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CN
China
Prior art keywords
peptide
peptides
disease
cell
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202411888874.5A
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English (en)
Chinese (zh)
Inventor
艾伦·欧瓦迪亚
艾维·班-席蒙
伊拉娜·科恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immune Pharmaceuticals Ltd
Original Assignee
Immune Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Pharmaceuticals Ltd filed Critical Immune Pharmaceuticals Ltd
Publication of CN119708144A publication Critical patent/CN119708144A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Gastroenterology & Hepatology (AREA)
CN202411888874.5A 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法 Pending CN119708144A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL272074A IL272074B2 (en) 2020-01-15 2020-01-15 Peptide compounds and methods of treating diseases using same
IL272074 2020-01-15
CN202180017719.4A CN115942948B (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
PCT/IL2021/050044 WO2021144798A1 (en) 2020-01-15 2021-01-14 Peptide compounds and methods of treating diseases using same

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN202180017719.4A Division CN115942948B (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法

Publications (1)

Publication Number Publication Date
CN119708144A true CN119708144A (zh) 2025-03-28

Family

ID=76863930

Family Applications (6)

Application Number Title Priority Date Filing Date
CN202411888874.5A Pending CN119708144A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888865.6A Pending CN119708140A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888870.7A Pending CN119708142A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888869.4A Pending CN119708141A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888873.0A Pending CN119708143A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202180017719.4A Active CN115942948B (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
CN202411888865.6A Pending CN119708140A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888870.7A Pending CN119708142A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888869.4A Pending CN119708141A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202411888873.0A Pending CN119708143A (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法
CN202180017719.4A Active CN115942948B (zh) 2020-01-15 2021-01-14 肽化合物及其治疗疾病的方法

Country Status (12)

Country Link
US (1) US20230049549A1 (enExample)
EP (1) EP4090347A1 (enExample)
JP (1) JP7809060B2 (enExample)
KR (1) KR20220145826A (enExample)
CN (6) CN119708144A (enExample)
AU (1) AU2021207415A1 (enExample)
BR (1) BR112022013978A2 (enExample)
CA (1) CA3167139A1 (enExample)
CO (1) CO2022011101A2 (enExample)
IL (1) IL272074B2 (enExample)
MX (1) MX2022008746A (enExample)
WO (1) WO2021144798A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL280101B2 (en) 2018-07-11 2025-05-01 Immunity Pharma Ltd Peptide compounds and their therapeutic uses

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
EP0928968A1 (en) 1998-01-12 1999-07-14 Universität Basel Screening method for apoptosis and necrosis
CA2443314C (en) 2001-04-03 2006-03-21 The Board Of Trustees Of The Leland Stanford Junior University Method of imaging cell death in vivo
WO2003037172A2 (en) * 2001-11-01 2003-05-08 Gpc Biotech Inc. Endothelial-cell binding peptides for diagnosis and therapy
AU2005276117C1 (en) * 2004-08-23 2013-04-18 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Peptide inhibitors for mediating stress responses
US8648045B2 (en) * 2005-03-10 2014-02-11 Ben Gurion University Of The Negev Research And Development Authority Ltd. VDAC1 compositions and methods of use thereof for regulating apoptosis
CA2737924A1 (en) * 2008-10-06 2010-04-15 Joshua Robert Schultz Methods of treating inflammation
US20130096070A1 (en) * 2009-04-07 2013-04-18 University Of Kansas Peptide targeting of inner ear cells
CA2836503C (en) * 2011-05-23 2020-09-22 Yeda Research And Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
BR112017022845A2 (pt) * 2015-04-23 2018-07-17 Nantomics, Llc neoepítopos de câncer
IL280101B2 (en) * 2018-07-11 2025-05-01 Immunity Pharma Ltd Peptide compounds and their therapeutic uses

Also Published As

Publication number Publication date
MX2022008746A (es) 2022-10-13
WO2021144798A1 (en) 2021-07-22
CN119708141A (zh) 2025-03-28
JP7809060B2 (ja) 2026-01-30
CN115942948A (zh) 2023-04-07
CA3167139A1 (en) 2021-07-22
EP4090347A1 (en) 2022-11-23
US20230049549A1 (en) 2023-02-16
CN119708142A (zh) 2025-03-28
CO2022011101A2 (es) 2022-11-08
AU2021207415A1 (en) 2022-09-08
JP2023510019A (ja) 2023-03-10
IL272074B2 (en) 2024-12-01
CN119708143A (zh) 2025-03-28
IL272074A (en) 2021-07-29
CN115942948B (zh) 2025-01-14
BR112022013978A2 (pt) 2022-10-11
CN119708140A (zh) 2025-03-28
KR20220145826A (ko) 2022-10-31
IL272074B1 (en) 2024-08-01

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