CN119343456A - 用于改进型免疫疗法的方法和包括融合蛋白的组合物 - Google Patents

用于改进型免疫疗法的方法和包括融合蛋白的组合物 Download PDF

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CN119343456A
CN119343456A CN202380041860.7A CN202380041860A CN119343456A CN 119343456 A CN119343456 A CN 119343456A CN 202380041860 A CN202380041860 A CN 202380041860A CN 119343456 A CN119343456 A CN 119343456A
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cells
cell
lymphocyte
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Chinese (zh)
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N·E·桑贾纳
M·莱古特
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New York University
New York Genome Center
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New York University
New York Genome Center
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C12N15/09—Recombinant DNA-technology
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CN202380041860.7A 2022-03-15 2023-03-15 用于改进型免疫疗法的方法和包括融合蛋白的组合物 Pending CN119343456A (zh)

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US202263320100P 2022-03-15 2022-03-15
US63/320,100 2022-03-15
PCT/US2023/064452 WO2023178187A2 (en) 2022-03-15 2023-03-15 Methods and compositions comprising fusion proteins for improved immunotherapies

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ES2778651T3 (es) * 2015-10-09 2020-08-11 Miltenyi Biotec Technology Inc Receptores de antígeno quimérico y métodos de uso
US12083148B2 (en) * 2017-02-22 2024-09-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. IL13Ra2-binding chimeric antigen receptors
CA3129263A1 (en) * 2019-02-08 2020-08-13 Dna Twopointo Inc. Transposon-based modifications of immune cells
KR102957801B1 (ko) * 2019-06-27 2026-04-28 주식회사 유틸렉스 4-1bb 공동자극 도메인을 갖는 키메라 항원 수용체
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CA3245638A1 (en) 2023-09-21
US20250195572A1 (en) 2025-06-19
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