CN1190593A

CN1190593A - Medicine for the treatment of rheumatism and arthritis

Info

Publication number: CN1190593A
Application number: CN98110035A
Authority: CN
Inventors: 朱贵来; 王庆菊
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-01-23
Filing date: 1998-01-23
Publication date: 1998-08-19
Anticipated expiration: 2018-01-23
Also published as: CN1074670C

Abstract

The present invention disclosed a kind of Chinese proprietary medicine for treating rheumatic arthritis and rheumatoid arthritis. It is prepared up by using root of Chinese clematis, fructus chaenomelis, Sichuan aconite root, pseudo-ginseng, large-is obvious and there is no toxic side effect.

Description

Medicine for the treatment of rheumatism and arthritis

The invention belongs to-medicine of kind of treatment rheumatism, rheumatoid arthritis, specifically is the expelling wind and removing dampness Chinese patent medicine that preparation of raw material forms with the Chinese herbal medicine.

Rheumatism, rheumatoid arthritis are a kind of obstinate commonly encountered diseases, do not have age-sex's branch; Western medicine adopts symptomatic treatment injection penicillin or hormone medicine more at present, oral aspirin, indometacin etc., with medicine time length health there is bigger infringement, cause anasarca, gastrointestinal irriate, and drug withdrawal is promptly recurred, and prescriptions of Chinese medicine does not have fixedly prescription yet, and is decoction, takes fried very inconvenient; Or adopt oral Fructus Chaenomelis Pilulae, anti-rheumatism sheet, Radix Tripterygii Wilfordii ball, rheumatism horse anter etc., because of medicine is single, curative effect is not good.

The object of the present invention is to provide a kind of antiinflammatory expelling wind and removing dampness, and have no side effect treatment rheumatism, rheumatoid Chinese patent medicine.

Solution of the present invention is based on motherland's Chinese medicine to rheumatism, the sick pathogenetic understanding of rheumatoid arthritis, the Therapeutic Principle, achieve with reference to modern pharmacological research, select expelling wind and removing dampness for use, strengthening spleen, tonifying kidney, blood-activating stasis-removing kind Chinese medicine reaches antiinflammatory and relieves the pain and remove the purpose of rheumatism, rheumatoid symptom.

Medicine for the treatment of rheumatism and arthritis of the present invention is to be made by the following portions by weight proportion raw material:

Radix Clematidis 6-18 part, Fructus Chaenomelis 12-20 part, Radix Aconiti 3-6 part, Radix Notoginseng 10-20 part, Radix Gentianae Macrophyllae 6-9 part, Cortex schizophragmatis integrifolii radicis 15-30 part.

The present invention adopts such scheme to treat rheumatism, rheumatoid arthritis is evident in efficacy, effective percentage 100%, and cure rate 85%, the analgesia blood circulation promoting and blood stasis dispelling is rapid, has no side effect taking convenience.

Drug action mechanism of the present invention is as follows:

Among the present invention, Radix Clematidis, hot, salty, warm; Return 12 warps, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, softening the hard mass sending down the fishbone, detoxifcation, detumescence.Modern pharmacological research proves: the Main Ingredients and Appearance of Radix Clematidis is: in the Radix Pulsatillae lactone, sterol, saccharide, Saponin, phenols, amino acid salts, organic acid (see " Chinese medicine " Chengdu University of Traditional Chinese Medicine edit the 311st page).Fructus Chaenomelis, sour, warm; Go into liver, spleen channel, Shujin arm alive, detumescence relieves the pain; Modern pharmacological research proves that the Main Ingredients and Appearance of Fructus Chaenomelis is: Saponin, flower ketone glycoside have obvious detumescence effect (seeing " Chinese country doctor's teaching material " People's Health Publisher, the 98th page) to arthritis.Radix Aconiti, is apt to into through arm the cold-damp of dispeling the wind numbness, severe and migratory arthralgia pain at hot, bitter, heat; Modern pharmacological research proof Radix Aconiti Main Ingredients and Appearance is: aconitine, and aconite secondary alkali, aconines etc. have analgesia, calmness, antiinflammatory action.(seeing the chief editor of " Chinese materia medica " Chengdu University of Traditional Chinese Medicine, the 306th page of Sichuan science tech publishing house).Radix Notoginseng, sweet, little hardship, temperature; Go into liver, bone, month intestinal warp, dissipating blood stasis hemostasis, reducing swelling and alleviating pain; Modern pharmacological research proves that the Radix Notoginseng Main Ingredients and Appearance is: arasaponin first, arasaponin second, arasaponin A, panaxatriol, panoxadiol, flavone, alkaloid (see the chief editor of " Chinese medicine " Chengdu University of Traditional Chinese Medicine etc. 352 pages).Radix Gentianae Macrophyllae, sweet, be slightly cold, go into stomach, liver and gall warp, wind-damp dispelling, reducing the asthenic fever, clearing away damp-heat, modern pharmacological research prove that the Main Ingredients and Appearance of Radix Gentianae Macrophyllae is: alkaloid (gentianin, second, third) saccharide; The Radix Gentianae Macrophyllae first is brought down a fever, analgesia, hypotensive effect.(seeing the chief editor of " Chinese medicine " Chengdu Chinese medicine university, the 309th page).Cortex schizophragmatis integrifolii radicis, sweet, little hardship, flat; Go into liver, spleen, stomach warp, the logical arm that dispels the wind, reinforcing waist and strengthening bone; Modern pharmacological research proves that the Main Ingredients and Appearance of Cortex schizophragmatis integrifolii radicis is: contain lactone (coumarin) phenols, aminoacid etc.; Can invigorating the liver and kidney, the strong stomach of waist (seeing the chief editor of " Chinese materia medica " Chengdu University of Traditional Chinese Medicine, the 330th page) by force.

All medicines share, and dispelling cold and removing dampness, blood circulation promoting and blood stasis dispelling, antipyretic-antalgic, benefiting qi and nourishing blood, strong muscles and bones increase body immunity, reach eliminating pathogenic factor for supporting vital QI, the arthritic purpose of vital QI recovered after pathogens eliminated treatment rheumatic and rheumatoid.

For showing the therapeutic effect of medicine of the present invention to rheumatism, rheumatoid, arthritis, through the clinical observation of 126 routine systems, and get medical history, patient's 46 examples that the state of an illness is suitable are organized in contrast, adopt the party regulation western medicine therapy, get 80 examples as test group, take medicine of the present invention and only obey once each 3 grams every day, the observation period is six months.

Adopt identical standard to add up at last, criterion of therapeutical effect is:

(1) symptom after taking medicine alleviates or disappearance person is considered as effectively immediately;

(2) sx need still to continue the pill taker for not healing;

(3) drug withdrawal is after 1 year, and the recidivist is not complete;

Table 1 matched group curative effect situation

Table 2 test curative effect situation:

Below in conjunction with embodiment the present invention is described in detail

Embodiment 1 get Radix Clematidis 16g, Fructus Chaenomelis 18g, Radix Aconiti 5g, Radix Notoginseng 18g, Radix Gentianae Macrophyllae 9g, Cortex schizophragmatis integrifolii radicis 26g go clean shine extremely dried, pulverize powdery powder more jointly, incapsulate, each 1g promptly makes wooden invention expelling wind and removing dampness medicine, obey once oral every day sleep evening before clothes three, got final product in six months.

Embodiment 2 gets Radix Clematidis 10g, Fructus Chaenomelis 15g, Radix Aconiti 4g, Radix Notoginseng 15g, Radix Gentianae Macrophyllae 8g, Cortex schizophragmatis integrifolii radicis 20g, and the method for making instructions about how to take medicine cure mainly rheumatoid, rheumatic arthritis merging contracture articular instability modification patient with implementing 1.

Embodiment 3 gets Radix Clematidis 6g, Fructus Chaenomelis 12g, Radix Aconiti 3g, Radix Notoginseng 10g, Radix Gentianae Macrophyllae 7g, Cortex schizophragmatis integrifolii radicis 16g, and method cures mainly rheumatism, the concurrent interior moist cardiac of arthritis with implementing 1.

Claims

1, Medicine for the treatment of rheumatism and arthritis is characterized in that it is the medicament of being made by the following portions by weight proportion raw material.

2, Medicine for the treatment of rheumatism and arthritis according to claim 1, wherein each raw materials in part by weight proportioning is:

16 parts of Radix Clematidis, 18 parts of Fructus Chaenomeliss, 5 parts of Radix Aconitis, 18 parts of Radix Notoginseng, 9 parts of Radix Gentianae Macrophyllae, 26 parts of Cortex schizophragmatis integrifolii radiciss.

3, Medicine for the treatment of rheumatism and arthritis according to claim 1, wherein each raw materials in part by weight proportioning is:

10 parts of Radix Clematidis, 15 parts of Fructus Chaenomeliss, 4 parts of Radix Aconitis, 15 parts of Radix Notoginseng, 8 parts of Radix Gentianae Macrophyllae, 20 parts of Cortex schizophragmatis integrifolii radiciss.

4, Medicine for the treatment of rheumatism and arthritis according to claim 1, wherein each raw materials in part by weight proportioning is:

6 parts of Radix Clematidis, 12 parts of Fructus Chaenomeliss, 3 parts of Radix Aconitis, 10 parts of Radix Notoginseng, 7 parts of Radix Gentianae Macrophyllae, 16 parts of Cortex schizophragmatis integrifolii radiciss.