CN119013394A - 用于治疗乙型肝炎病毒感染的组合物和方法 - Google Patents

用于治疗乙型肝炎病毒感染的组合物和方法 Download PDF

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Publication number
CN119013394A
CN119013394A CN202280077560.XA CN202280077560A CN119013394A CN 119013394 A CN119013394 A CN 119013394A CN 202280077560 A CN202280077560 A CN 202280077560A CN 119013394 A CN119013394 A CN 119013394A
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China
Prior art keywords
seq
hbv
tada
deaminase
amino acid
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Pending
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CN202280077560.XA
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English (en)
Chinese (zh)
Inventor
法比安·祖林
玛丽亚·瓜达卢佩·马丁内斯
芭芭拉·特斯托尼
埃琳娜·斯梅卡洛娃
路易斯·巴雷拉
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French National Institute Of Health And Medicine
Bim Medical Co ltd
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French National Institute Of Health And Medicine
Bim Medical Co ltd
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Publication of CN119013394A publication Critical patent/CN119013394A/zh
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
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CN202280077560.XA 2021-09-27 2022-09-27 用于治疗乙型肝炎病毒感染的组合物和方法 Pending CN119013394A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163248938P 2021-09-27 2021-09-27
US63/248,938 2021-09-27
US202263357623P 2022-06-30 2022-06-30
US63/357,623 2022-06-30
US202263371634P 2022-08-16 2022-08-16
US63/371,634 2022-08-16
PCT/US2022/077105 WO2023049935A1 (en) 2021-09-27 2022-09-27 Compositions and methods for treating hepatitis b virus infection

Publications (1)

Publication Number Publication Date
CN119013394A true CN119013394A (zh) 2024-11-22

Family

ID=85721334

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280077560.XA Pending CN119013394A (zh) 2021-09-27 2022-09-27 用于治疗乙型肝炎病毒感染的组合物和方法

Country Status (8)

Country Link
US (1) US20240294914A1 (https=)
EP (1) EP4408986A4 (https=)
JP (1) JP2024534639A (https=)
KR (1) KR20240111821A (https=)
CN (1) CN119013394A (https=)
AU (1) AU2022353130A1 (https=)
CA (1) CA3233413A1 (https=)
WO (1) WO2023049935A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025126049A2 (en) * 2023-12-11 2025-06-19 Crispr Therapeutics Ag Multiplex gene editing

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2966170A1 (en) * 2014-07-10 2016-01-13 Heinrich-Pette-Institut Leibniz-Institut für experimentelle Virologie-Stiftung bürgerlichen Rechts - HBV inactivation
CA3001351A1 (en) * 2015-10-21 2017-04-27 Editas Medicine, Inc. Crispr/cas-related methods and compositions for treating hepatitis b virus
KR101842131B1 (ko) * 2016-09-05 2018-03-27 연세대학교 산학협력단 Hbv를 표적으로 하는 유전자 가위 및 이를 포함하는 hbv 감염 치료용 조성물
US11566236B2 (en) * 2018-02-05 2023-01-31 Vertex Pharmaceuticals Incorporated Materials and methods for treatment of hemoglobinopathies
CA3139324A1 (en) * 2019-05-10 2020-11-19 Beam Therapeutics Inc. Compositions and methods for treating hepatitis b

Also Published As

Publication number Publication date
EP4408986A4 (en) 2026-01-21
US20240294914A1 (en) 2024-09-05
EP4408986A1 (en) 2024-08-07
WO2023049935A1 (en) 2023-03-30
CA3233413A1 (en) 2023-03-30
JP2024534639A (ja) 2024-09-20
KR20240111821A (ko) 2024-07-17
AU2022353130A1 (en) 2024-04-11

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