CN119013093A - 包括使用二嵌段或三嵌段共聚物的屏障的纳米孔装置以及制造该纳米孔装置的方法 - Google Patents

包括使用二嵌段或三嵌段共聚物的屏障的纳米孔装置以及制造该纳米孔装置的方法 Download PDF

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Publication number
CN119013093A
CN119013093A CN202380031551.1A CN202380031551A CN119013093A CN 119013093 A CN119013093 A CN 119013093A CN 202380031551 A CN202380031551 A CN 202380031551A CN 119013093 A CN119013093 A CN 119013093A
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CN
China
Prior art keywords
barrier
block
hydrophilic
hydrophobic
blocks
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380031551.1A
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English (en)
Chinese (zh)
Inventor
A·里奇兹
A·康德-冈萨雷斯
O·厄特利
C·瓦科涅
D·加罗尔迪尼
M·A·阿莱曼·加西亚
Y·维波娜
I·科克西斯
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Illumina Inc
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Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of CN119013093A publication Critical patent/CN119013093A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • B01D69/142—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers"
    • B01D69/144—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes with "carriers" containing embedded or bound biomolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/22—After-treatment of expandable particles; Forming foamed products
    • C08J9/228—Forming foamed products
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2205/00—Foams characterised by their properties
    • C08J2205/04—Foams characterised by their properties characterised by the foam pores
    • C08J2205/042—Nanopores, i.e. the average diameter being smaller than 0,1 micrometer
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2353/00—Characterised by the use of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202380031551.1A 2022-03-31 2023-03-30 包括使用二嵌段或三嵌段共聚物的屏障的纳米孔装置以及制造该纳米孔装置的方法 Pending CN119013093A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263325726P 2022-03-31 2022-03-31
US63/325,726 2022-03-31
PCT/EP2023/058383 WO2023187104A1 (en) 2022-03-31 2023-03-30 Nanopore devices including barriers using diblock or triblock copolymers, and methods of making the same

Publications (1)

Publication Number Publication Date
CN119013093A true CN119013093A (zh) 2024-11-22

Family

ID=86052136

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380031551.1A Pending CN119013093A (zh) 2022-03-31 2023-03-30 包括使用二嵌段或三嵌段共聚物的屏障的纳米孔装置以及制造该纳米孔装置的方法

Country Status (6)

Country Link
US (1) US20230312856A1 (https=)
EP (1) EP4499282A1 (https=)
JP (1) JP2025513682A (https=)
CN (1) CN119013093A (https=)
AU (1) AU2023246642A1 (https=)
WO (1) WO2023187104A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026006622A2 (en) 2024-06-28 2026-01-02 Illumina, Inc. Sequencing full-complement polynucleotides using nanopores
US20260085352A1 (en) 2024-09-26 2026-03-26 Illumina, Inc. Pulsed recharging for nanopore devices

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795782A (en) 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
US7939249B2 (en) 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step
DK2171088T3 (en) 2007-06-19 2016-01-25 Stratos Genomics Inc Nucleic acid sequencing in a high yield by expansion
WO2009055617A1 (en) 2007-10-23 2009-04-30 Stratos Genomics Inc. High throughput nucleic acid sequencing by spacing
EP2391726B1 (en) 2009-01-29 2015-09-23 Stratos Genomics Inc. High throughput nucleic acid sequencing by expansion and related methods
WO2012003330A2 (en) 2010-06-30 2012-01-05 Stratos Genomics, Inc Multiplexed identification of nucleic acid sequences
KR102083695B1 (ko) 2012-04-10 2020-03-02 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 리세닌 기공
WO2014074922A1 (en) 2012-11-09 2014-05-15 Stratos Genomics, Inc. Concentrating a target molecule for sensing by a nanopore
EP3143158A1 (en) 2014-05-14 2017-03-22 Stratos Genomics, Inc. Translocation control for sensing by a nanopore
ES2846746T3 (es) 2014-06-03 2021-07-29 Illumina Inc Composiciones, sistemas y métodos para detectar acontecimientos usando fijaciones ancladas o adyacentes a nanoporos
AU2015349730C1 (en) 2014-11-20 2020-04-30 F. Hoffmann-La Roche Ag Nulceoside phosphoroamidate esters and derivatives thereof, use and synthesis thereof
EP3377648B1 (en) 2015-11-16 2021-01-06 Stratos Genomics, Inc. Dp04 polymerase variants
JP7012841B2 (ja) * 2017-10-23 2022-01-28 エフ．ホフマン－ラ ロシュ アーゲー 浸透性の不均衡を利用した膜内のタンパク質ナノポアの除去および再挿入
CN112831395B (zh) * 2019-11-25 2024-01-16 深圳华大生命科学研究院 用于纳米孔测序的类细胞膜
US20230090867A1 (en) 2021-09-22 2023-03-23 Illumina, Inc. Sequencing polynucleotides using nanopores

Also Published As

Publication number Publication date
JP2025513682A (ja) 2025-04-30
AU2023246642A1 (en) 2024-08-29
US20230312856A1 (en) 2023-10-05
EP4499282A1 (en) 2025-02-05
WO2023187104A1 (en) 2023-10-05

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