CN118853594A - 嵌合痘病毒组合物及其用途 - Google Patents
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- CN118853594A CN118853594A CN202410528631.4A CN202410528631A CN118853594A CN 118853594 A CN118853594 A CN 118853594A CN 202410528631 A CN202410528631 A CN 202410528631A CN 118853594 A CN118853594 A CN 118853594A
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24151—Methods of production or purification of viral material
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- Proteomics, Peptides & Aminoacids (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662372408P | 2016-08-09 | 2016-08-09 | |
| US62/372,408 | 2016-08-09 | ||
| US201762519010P | 2017-06-13 | 2017-06-13 | |
| US62/519,010 | 2017-06-13 | ||
| CN201780062335.8A CN110199018B (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
| PCT/US2017/046163 WO2018031694A1 (en) | 2016-08-09 | 2017-08-09 | Chimeric poxvirus compositions and uses thereof |
Related Parent Applications (1)
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| CN201780062335.8A Division CN110199018B (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
Publications (1)
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| CN118853594A true CN118853594A (zh) | 2024-10-29 |
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| CN202410528631.4A Pending CN118853594A (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
| CN202410528486.XA Pending CN118834840A (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
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| CN201780062335.8A Active CN110199018B (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
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| CN202410528486.XA Pending CN118834840A (zh) | 2016-08-09 | 2017-08-09 | 嵌合痘病毒组合物及其用途 |
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| Country | Link |
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| EP (1) | EP3497209A4 (enExample) |
| JP (4) | JP7023929B2 (enExample) |
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| CA (1) | CA3033512A1 (enExample) |
| MX (1) | MX2019001672A (enExample) |
| RU (2) | RU2757002C2 (enExample) |
| WO (1) | WO2018031694A1 (enExample) |
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| ES2949648T3 (es) | 2012-12-20 | 2023-10-02 | Purdue Research Foundation | Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer |
| JP2018510143A (ja) | 2015-02-25 | 2018-04-12 | メモリアル スローン ケタリング キャンサー センター | 不活化非複製改変ワクシニアウイルスアンカラ（ｍｖａ）の固形腫瘍のための単独療法又は免疫チェックポイント遮断剤併用における使用 |
| CA2982896A1 (en) | 2015-04-17 | 2016-10-20 | Memorial Sloan Kettering Cancer Center | Use of modified vaccinia ankara virus (mva) or mva with a deletion of virulence factor e8 as immunotherapeutic agent against solid tumors |
| SG11201807022XA (en) | 2016-02-25 | 2018-09-27 | Memorial Sloan Kettering Cancer Center | Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors |
| CN116440176A (zh) | 2016-02-25 | 2023-07-18 | 纪念斯隆凯特琳癌症中心 | 具有胸苷激酶缺失和具有或不具有人flt3l或gm-csf表达的复制型减毒痘苗病毒 |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| CA3033512A1 (en) * | 2016-08-09 | 2018-02-15 | City Of Hope | Chimeric poxvirus compositions and uses thereof |
| US11850262B2 (en) | 2017-02-28 | 2023-12-26 | Purdue Research Foundation | Compositions and methods for CAR T cell therapy |
| CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
| CN111163803B (zh) * | 2017-08-11 | 2025-05-09 | 希望之城公司 | 表达car t细胞靶物的溶瘤病毒及其用途 |
| BR112020014913A2 (pt) | 2018-01-22 | 2020-12-08 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Métodos para uso de células t car |
| CA3091674A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
| MX2020009262A (es) | 2018-03-07 | 2021-01-08 | Transgene | Vectores de parapoxvirus. |
| WO2019213173A1 (en) * | 2018-04-30 | 2019-11-07 | City Of Hope | Neural stem cell compositions including chimeric poxviruses for cancer treatment |
| WO2020056424A1 (en) | 2018-09-15 | 2020-03-19 | Memorial Sloan Kettering Cancer Center | Recombinant poxviruses for cancer immunotherapy |
| CN113583977B (zh) * | 2020-04-30 | 2025-06-06 | 杭州康万达医药科技有限公司 | 可受微小rna调控的分离的重组溶瘤痘病毒及其应用 |
| GB2614309A (en) | 2021-12-24 | 2023-07-05 | Stratosvir Ltd | Improved vaccinia virus vectors |
| WO2023213763A1 (en) * | 2022-05-02 | 2023-11-09 | Transgene | Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab |
| AU2023326730A1 (en) | 2022-08-18 | 2025-03-13 | Transgene | Chimeric poxviruses |
| WO2024245722A2 (en) * | 2023-05-26 | 2024-12-05 | Probiogen Ag | Rapid selection system for the generation of recombinant enveloped viruses |
| WO2025184411A1 (en) | 2024-02-27 | 2025-09-04 | Calidi Biotherapeutics (Nevada), Inc. | Serum-resistant eev viruses and uses thereof |
| CN120718864B (zh) * | 2025-08-28 | 2025-11-28 | 山东农业大学 | 一种高度不成熟鸭坦布苏病毒及其培养方法和应用 |
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| AT406376B (de) * | 1998-01-16 | 2000-04-25 | Immuno Ag | Chimäres poxvirus enthaltend eine retrovirale vektorkomponente |
| EP1268763A2 (en) | 2000-03-28 | 2003-01-02 | University Of Rochester | Methods of producing a library and methods of selecting polynucleotides |
| UA85379C2 (ru) * | 2002-11-25 | 2009-01-26 | Бавариан Нордик А/С | Рекомбинантный поксвирус, содержащий как минимум два ati промотора коровьей оспы |
| EP2028270B9 (en) * | 2003-06-18 | 2012-04-25 | Genelux Corporation | Modified recombinant vaccinia viruses, uses thereof |
| WO2008100292A2 (en) | 2006-10-16 | 2008-08-21 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| ES2535633T3 (es) * | 2007-11-19 | 2015-05-13 | Transgene Sa | Vectores oncolíticos poxvirales |
| CA2795695A1 (en) | 2010-04-09 | 2011-10-13 | The University Of Tokyo | Microrna-controlled recombinant vaccinia virus and use thereof |
| CA2836299A1 (en) | 2011-04-15 | 2012-10-18 | Genelux Corporation | Clonal strains of attenuated vaccinia viruses and methods of use thereof |
| JP2015520754A (ja) | 2012-05-18 | 2015-07-23 | オタゴ イノベーション リミテッド | 創傷治癒のための組合せ治療および組成物 |
| WO2015103438A2 (en) * | 2014-01-02 | 2015-07-09 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| CA3033512A1 (en) * | 2016-08-09 | 2018-02-15 | City Of Hope | Chimeric poxvirus compositions and uses thereof |
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| EP3497209A1 (en) | 2019-06-19 |
| JP2025072482A (ja) | 2025-05-09 |
| JP2019524131A (ja) | 2019-09-05 |
| BR112019002646A2 (pt) | 2019-10-08 |
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| RU2021128158A (ru) | 2022-04-07 |
| KR20230113832A (ko) | 2023-08-01 |
| WO2018031694A1 (en) | 2018-02-15 |
| RU2757002C2 (ru) | 2021-10-08 |
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| KR20190038626A (ko) | 2019-04-08 |
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| JP2022065034A (ja) | 2022-04-26 |
| AU2023270200A1 (en) | 2024-01-25 |
| AU2017311380A1 (en) | 2019-03-28 |
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| US20190218522A1 (en) | 2019-07-18 |
| US20250084384A1 (en) | 2025-03-13 |
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| RU2019106319A3 (enExample) | 2021-03-17 |
| CN110199018B (zh) | 2024-06-07 |
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| KR102557818B1 (ko) | 2023-07-20 |
| JP7395628B2 (ja) | 2023-12-11 |
| JP7631485B2 (ja) | 2025-02-18 |
| CN118834840A (zh) | 2024-10-25 |
| CN110199018A (zh) | 2019-09-03 |
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