CN1186036C - Diabetes treating medicine and its prepn - Google Patents
Diabetes treating medicine and its prepn Download PDFInfo
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- CN1186036C CN1186036C CNB011351071A CN01135107A CN1186036C CN 1186036 C CN1186036 C CN 1186036C CN B011351071 A CNB011351071 A CN B011351071A CN 01135107 A CN01135107 A CN 01135107A CN 1186036 C CN1186036 C CN 1186036C
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- fructus
- rhizoma atractylodis
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Abstract
The present invention discloses a medicine for treating diabetes, which can be prepared from more than ten medicines according to the certain proportion, such as trichosanthes root, pseudostellaria root, Chinese yam, cornus, Fructus Lycii, atractylodes, crataegus, astragalus root, foxnut, etc. The medicine can be prepared into powder, capsules and pills, and enables diabetic patients to lower blood glucose and urine glucose stably, prevents complications and has no side effect.
Description
Technical field
The invention belongs to the medicine of treatment diabetes, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.
Background technology
Diabetes are " sources of all kinds of diseases and ailments ", and number of patients is more at present, have become the third-largest killer who threatens human survival, and along with aged tendency of population and growth in the living standard, this disease will increase progressively with annual 2～3% number.The medicine of treatment diabetes commonly used is a biguanides, but this medicine easily makes the digestive system function disorder, and D-860 glyburide also is the medicine of treatment diabetes, and there is the defective that hypoglycemic effect is lower and the complication prevention effect is not good enough in this medicine.Though also have the medicine of many treatment diabetes at present, but Western medicine generally all has side effect, and the Chinese medicine of producing at present needs just can demonstrate curative effect preferably with some Western medicine adapteds mostly, and said medicine all generations of prevent diabetes complication well when using separately.
Summary of the invention
The object of the present invention is to provide a kind of medicine that can make diabetics steady decrease blood glucose and glucose in urine and the better complication prevention of energy.
Another object of the present invention provides the preparation method of this medicine.
Solution of the present invention is on the basis of conscientiously studying to onset diabetes mechanism, and the medicine of choosing tonifying QI to produce body fluid, heat clearing away kidney tonifying, blood circulation promoting and blood stasis dispelling, the body resistance strengthening and constitution consolidating forms through appropriate compatibility.
Medicine of the present invention is made up of following component: (consumption is a weight portion)
Radix Trichosanthis 10～15 Radix Pseudostellariaes 20～30 Rhizoma Dioscoreaes 20～30 Fructus Corni 15～20
Fructus Lycii 15～20 Rhizoma Atractylodis Macrocephalaes 15～20 Fructus Crataegis 20～30 Radixs Astragali 30～50
Semen Euryales 15～20 Fructus Mumes 10～15 Herba Agrimoniaes 15～20 Rhizoma Atractylodis 10～15
Cortex Moutan 10～15 Cortex Phellodendris 10～18 Radix Rehmanniae 20～30 Radix Scrophulariaes 20～30
Herb Gynostemmae Pentaphylli 25～45 Radix Glycyrrhizaes 6
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
Radix Trichosanthis 12～14 Radix Pseudostellariaes 24～27 Rhizoma Dioscoreaes 24～28 Fructus Corni 18～20
Fructus Lycii 18～20 Rhizoma Atractylodis Macrocephalaes 15～18 Fructus Crataegis 20～25 Radixs Astragali 38～48
Semen Euryales 18～20 Fructus Mumes 13～15 Herba Agrimoniaes 17～20 Rhizoma Atractylodis 12～15
Cortex Moutan 10～13 Cortex Phellodendris 10～15 Radix Rehmanniae 20～28 Radix Scrophulariaes 20～25
Herb Gynostemmae Pentaphylli 25～38 Radix Glycyrrhizaes 6
Above-mentioned each component is made medicine production method of the present invention is: medicine in will filling a prescription is pulverized, and crosses 100 mesh sieves, get sieve down thin medicated powder incapsulate, every capsules contains medicated powder 0.2 gram.
The also available following method production of medicine of the present invention: the medicine in will filling a prescription is pulverized earlier, after 100 mesh sieves, the medicated powder of getting after sieving is standby, pour boiled water again into after Semen setariae put into container, Semen setariae surface is scalded to being clamminess, get the grain of rice that scalds after sticking, place it in the container that is equipped with medicated powder as the pill embryo, be rolled into the piller that particle diameter is 3～4mm, these pillers put into baking oven heat 60～80 ℃ and make its oven dry.
In this prescription, Radix Pseudostellariae, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Semen Euryales are mainly used in invigorating QI to consolidate the body surface resistance, dampness diuretic, spleen invigorating yin nourishing, elevate a turnable ladder yang-energy.
Radix Trichosanthis, the Radix Rehmanniae, Radix Scrophulariae have promoting the production of body fluid to quench thirst, removing heat from blood yin nourishing, heat-clearing and toxic substances removing, fall the effect of heart-fire, tonifying kidney-yin.
Fructus Corni, Fructus Lycii, Fructus Mume, Fructus Crataegi, astringent or styptic treatment for spontaneous sweating, promoting the production of body fluid to quench thirst can promote the production of body fluid.
Herba Agrimoniae, Cortex Moutan, Cortex Phellodendri have the effect that restrains hidroschesis, removing heat from blood and promoting blood circulation, prevents spiritlessness and weakness.
Ingredient among analysis the present invention as can be known, contain the necessary aminoacid of protein, multivitamin, carotene and human body in these medicines, these compositions have played QI invigorating, have nourished blood, the effect of spleen-invigorating and kidney-strengthening, enhancing body immunity, prevented the generation of complication, also contain water-soluble cellulose and Flavonoid substances in these medicines, therefore the effect of blood sugar lowering, blood fat reducing and blood pressure lowering is arranged.
In order to show the therapeutic effect of Chinese medicine of the present invention, once selected for use 80 routine patients to organize as treatment, among these patients, age is 16～30 years old person 3 people, 31～45 years old person 6 people, 46～60 years old person 21 people, 61～75 years old person 50 people, on inspection, patient's fasting glucose is more than 10.2mmol/L, and glucose in urine is 55～111.1mmol/L.Choose 80 examples and treatment group patient's age, medical history simultaneously, patient that the state of an illness is suitable organizes in contrast, proves curative effect of medication of the present invention with this.
During the treatment, treatment group patient other any medicines of stopping using only adopt the medicine among the present invention, take night and morning, and each dose is 6 grams, and the patient of matched group takes D-860 glyburide medicine, and the instructions of taking by specification of this medicine requires to take.Treatment group and matched group are all treated and were observed three months, do inspection again, and its result is as follows:
The therapeutic effect that can draw medicine of the present invention from The above results obviously is better than the therapeutic effect of D-860 glyburide.
In order to prove the effect of this chemoprophylaxis complication, above-mentioned patient to be followed the tracks of observed in 6 years, its effect sees the following form:
Treatment group and matched group complication onset state table
From above-mentioned data as can be seen the present invention treatment diabetes and complication prevention are all had good effect.
The specific embodiment
Embodiment 1:
Take by weighing qualified medicine (unit is kilogram) by following proportioning:
Radix Trichosanthis 10 Radix Pseudostellariaes 20 Rhizoma Dioscoreaes 20 Fructus Corni 15
Fructus Lycii 20 Rhizoma Atractylodis Macrocephalaes 20 Fructus Crataegis 30 Radixs Astragali 50
Semen Euryales 18 Fructus Mumes 13 Herba Agrimoniaes 18 Rhizoma Atractylodis 13
Cortex Moutan 13 Cortex Phellodendris 13 Radix Rehmanniae 25 Radix Scrophulariaes 25
Herb Gynostemmae Pentaphylli 28 Radix Glycyrrhizaes 6
The medicine that takes by weighing is pulverized, crossed 100 mesh sieves, get sieve fine powder bottling down, promptly make the powder of hypoglycemic medicine.
Embodiment 2:
Take by weighing medicine (unit is kilogram) by following proportioning:
Radix Trichosanthis 15 Radix Pseudostellariaes 30 Rhizoma Dioscoreaes 30 Fructus Corni 20
Fructus Lycii 15 Rhizoma Atractylodis Macrocephalaes 15 Fructus Crataegis 20 Radixs Astragali 30
Semen Euryales 20 Fructus Mumes 15 Herba Agrimoniaes 20 Rhizoma Atractylodis 15
Cortex Moutan 10 Cortex Phellodendris 10 Radix Rehmanniae 20 Radix Scrophulariaes 20
Herb Gynostemmae Pentaphylli 45 Radix Glycyrrhizaes 6
The method of the medicine of said ratio being made medicine of the present invention is:
Said medicine is at first pulverized, crossed 100 mesh sieves, the medicated powder of getting after sieving is standby.Semen setariae is put into container pour boiled water again into, Semen setariae surface is scalded to being clamminess, take out the small rice grain that scalds after sticking as the pill embryo, and put it in the container that is equipped with medicated powder, be rolled into the piller that particle diameter is 3～4mm.
These pillers are put into baking oven heats 60～80 ℃ and makes its oven dry.
The bottling of pill after the oven dry is got final product.
Embodiment 3:
Take by weighing medicine (unit is kilogram) by following proportioning:
Radix Trichosanthis 12 Radix Pseudostellariaes 24 Rhizoma Dioscoreaes 24 Fructus Corni 17
Fructus Lycii 18 Rhizoma Atractylodis Macrocephalaes 18 Fructus Crataegis 28 Radixs Astragali 48
Semen Euryales 15 Fructus Mumes 10 Herba Agrimoniaes 15 Rhizoma Atractylodis 10
Cortex Moutan 15 Cortex Phellodendris 18 Radix Rehmanniae 30 Radix Scrophulariaes 30
Herb Gynostemmae Pentaphylli 25 Radix Glycyrrhizaes 6
Method according to embodiment 2 is made pill.
Embodiment 4:
Take by weighing medicine (unit is kilogram) by following proportioning:
Radix Trichosanthis 14 Radix Pseudostellariaes 27 Rhizoma Dioscoreaes 28 Fructus Corni 18
Fructus Lycii 19 Rhizoma Atractylodis Macrocephalaes 17 Fructus Crataegis 25 Radixs Astragali 38
Semen Euryales 19 Fructus Mumes 14 Herba Agrimoniaes 17 Rhizoma Atractylodis 12
Cortex Moutan 14 Cortex Phellodendris 15 Radix Rehmanniae 28 Radix Scrophulariaes 28
Herb Gynostemmae Pentaphylli 38 Radix Glycyrrhizaes 6
Method by embodiment 1 is made medicated powder, medicated powder is incapsulated again, and every capsules contains medicated powder 0.2 gram.
Embodiment 5:
Take by weighing medicine (unit is kilogram) by following proportioning:
Radix Trichosanthis 12 Radix Pseudostellariaes 25 Rhizoma Dioscoreaes 25 Fructus Corni 20
Fructus Lycii 20 Rhizoma Atractylodis Macrocephalaes 15 Fructus Crataegis 20 Radixs Astragali 40
Semen Euryales 20 Fructus Mumes 15 Herba Agrimoniaes 20 Rhizoma Atractylodis 12
Cortex Moutan 12 Cortex Phellodendris 13 Radix Rehmanniae 25 Radix Scrophulariaes 20
Herb Gynostemmae Pentaphylli 30 Radix Glycyrrhizaes 6
Compounding method by embodiment 2 is made pill.
Claims (5)
1, a kind of medicine for the treatment of diabetes is characterized in that it is made up of the medicine of following weight parts proportioning:
Radix Trichosanthis 10～15 Radix Pseudostellariaes 20～30 Rhizoma Dioscoreaes 20～30 Fructus Corni 15～20
Fructus Lycii 15～20 Rhizoma Atractylodis Macrocephalaes 15～20 Fructus Crataegis 20～30 Radixs Astragali 30～50
Semen Euryales 15～20 Fructus Mumes 10～15 Herba Agrimoniaes 15～20 Rhizoma Atractylodis 10～15
Cortex Moutan 10～15 Cortex Phellodendris 10～18 Radix Rehmanniae 20～30 Radix Scrophulariaes 20～30
Herb Gynostemmae Pentaphylli 25～45 Radix Glycyrrhizaes 6.
2, the medicine of treatment diabetes according to claim 1 is characterized in that it is made up of the medicine of following weight parts proportioning:
Radix Trichosanthis 12～14 Radix Pseudostellariaes 24～27 Rhizoma Dioscoreaes 24～28 Fructus Corni 18～20
Fructus Lycii 18～20 Rhizoma Atractylodis Macrocephalaes 15～18 Fructus Crataegis 20～25 Radixs Astragali 38～48
Semen Euryales 18～20 Fructus Mumes 13～15 Herba Agrimoniaes 17～20 Rhizoma Atractylodis 12～15
Cortex Moutan 10～13 Cortex Phellodendris 10～15 Radix Rehmanniae 20～28 Radix Scrophulariaes 20～25
Herb Gynostemmae Pentaphylli 25～38 Radix Glycyrrhizaes 6.
3, the medicine of treatment diabetes according to claim 1 and 2 is characterized in that said medicament is a watered pill.
4, the medicine of treatment diabetes according to claim 1 and 2 is characterized in that said medicament is a capsule preparations.
5, the preparation method of the medicine of treatment diabetes according to claim 3, it is characterized in that medicine is pulverized earlier, after 100 mesh sieves, the medicated powder of getting after sieving is standby, pours boiled water again into after Semen setariae is put into container, and the Semen setariae surface is scalded to being clamminess, get the small rice grain that scalds after sticking as the pill embryo, place it in the container that is equipped with medicated powder, be rolled into the piller that particle diameter is 3～4mm, these pillers are put into baking oven heat 60～80 ℃ and make its oven dry.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011351071A CN1186036C (en) | 2001-11-08 | 2001-11-08 | Diabetes treating medicine and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011351071A CN1186036C (en) | 2001-11-08 | 2001-11-08 | Diabetes treating medicine and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1416854A CN1416854A (en) | 2003-05-14 |
| CN1186036C true CN1186036C (en) | 2005-01-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011351071A Expired - Fee Related CN1186036C (en) | 2001-11-08 | 2001-11-08 | Diabetes treating medicine and its prepn |
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| Country | Link |
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| CN (1) | CN1186036C (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233411A (en) * | 2017-05-23 | 2017-10-10 | 郑州市中医院 | A kind of antiallergic leads to nose sachet and preparation method thereof |
| CN107320580A (en) * | 2017-05-23 | 2017-11-07 | 郑州市中医院 | A kind of Chinese medicine rescues heart sachet and preparation method thereof |
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2001
- 2001-11-08 CN CNB011351071A patent/CN1186036C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1416854A (en) | 2003-05-14 |
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