CN1185304A

CN1185304A - Method for making up pathology working station system

Info

Publication number: CN1185304A
Application number: CN96116619A
Authority: CN
Inventors: 顾康庭
Original assignee: Individual
Current assignee: Individual
Priority date: 1996-12-17
Filing date: 1996-12-17
Publication date: 1998-06-24

Abstract

The pathological working station system formed of microscope camera head and microcomputer working station is characterized in that it adopts the microscopic camera system formed of biomicroscope with 256 grey scale illumination, matched with binocular tubes respectively equipped with black-white and color camera heads and reduction video-frequency adaptor, said camera heads are respectively connected to foreground and background service devices of its main body working station, and at the same time said system also is equipped with image display, printer, telephone, facsimile apparatus and uninterrupted power supply. Said main body working station and all branch working stations are networked by means of telephone lines to form said invented pathological working station system.

Description

The composing method of pathology workstation system

The present invention relates to the intelligent field of pathology work, specifically combining by microscope image pick-up system and microcomputer workstation.A kind of method that modernized devices such as realization Pathology Consultation, the biography certificate of reading sheet analysis, daily detection, data, image, management are formed.

Domestic and international application is at the most universal product of the micro-imaging system of medical science at present, by biological microscope, the CCD photographic head, compound radio-frequency and video signal relay process device, configurations such as image display monitor central monitoring system are formed, the said goods can't be satisfied with people to the requirement of image quality and the analysis of image, handle etc., in recent years again because the utilization of computer image processing and multimedia technology, the versatility image analysis system is represented its technical characterictic with IAS, the image analysis system of this versatility, although possessing abundant visual cell analysis function, but can only play qualitative analysis and relative value's comparison, can not be used to be diagnosed as purpose, the initial stage nineties, the U.S. release CAS-200 product (representing) with ICM wherein hardware configuration by biological microscope, the CCD photographic head, the high-performance power supply of specially joining for biological microscope, PC, special-purpose visual transaction card, the high-resolution picture display, output printer is formed, the integral optical density value can be scaled the quality of DNA, thereby the whether diploid cell of determining to be detected, express the distribution situation of individual cells dna content in the cell mass, quantitative expression goes out times body type degree virulent with it of tumor cell, though above-mentioned visual cell ICM analytical system photo densitometry meets the Lambert-Beer law, but require microscope light source to possess high stability constant-current source, when adopting monochromatic herring bone filter plate, then should not adopt the colored CCD photographic head, linearity to the CCD photographic head requires very high simultaneously, it is inhomogeneous to correct the background visual field that microscope optical system causes in addition, also must possess with the standard cell lines is the transmission of quantity value of benchmark, to measuring DNA result must be absolute value, non-IAS is relative value, though the release of CAS-200 system is technical at cancer diagnosis to be a breakthrough, maximum defective is the computer that the Kohler illumination biological microscope of employing non-quantitative is mixed accurate quantification.CAS-200 remedies the uneven error in the optical system background visual field that qualitative Kohler illumination causes, take to enroll software that pointwise corrects, the influence of the test error instrument of whole system is not more than ± 10%, tested cell is chosen scope and is not more than 60% of whole video picture picture.

The test point error that the purpose of this invention is to provide a kind of system is not more than 10%, the scope of choosing of tested cell is not less than 90% of whole video picture picture, and to set up normal human cell DNA be the 7.18Pg benchmark, even more importantly can finish the high quality image that the consultation of doctors is read sheet and obtained the photograph effect, the education of realization pathology, the composing method of a kind of pathology workstation system of scientific research, daily detection, remote transmission.

Technical scheme of the present invention: on biological microscope configuration binocular twoport lens barrel that 256 grade gradation lighting methods that adopt number of patent application 96116450.6 microscopes to use are formed or the twoport lens barrel black and white and colored CCD photographic head are installed respectively, be equipped with in the colored CCD utilizing camera interface contract at 1: 0.5 than video-frequency connector form microscope camera system, wherein the colored CCD photographic head is connected foreground, body of work station PC main frame respectively with the black-white CCD photographic head, main frame connects background server and VGA display, background server connects giant-screen high-resolution color image diplay respectively, color jet-ink or colored heat sublimation printer, telephone set, facsimile machine, the UPS uninterrupted power source is set in addition, and above-mentioned black-white CCD photographic head and colored CCD photographic head and 256 grades of gray scale illumination biological microscopies are by same means of power.

When removing background server, VGA color display, telephone set, facsimile machine then are biological sample microscopic image analytical system, and are made up of PC main frame, VGA color image display device, telephone set and UPS uninterrupted power source separately, then are the forked working station.

The present invention has quantified system analysis and arranges in pairs or groups mutually than joint and twoport body tube device by contracting with the colored CCD photographic head, pseudo-colours image card in the original system is replaced the true colour imagery sheet transaction card of the dual pathways input of redesign, so IAS and ICM two technology are combined together, improve biological sample microscopic image cell analysis system.Particularly important the present invention adopts 256 grades of quantitative lighting engineering of gray scale, fundamentally solve the whole configurations match needs of quantitative system, tested cell is chosen scope and is reached 90% of whole developing picture, can expand the selection of specimen and set up secondary transmission benchmark for the user simultaneously, and only use an image diplay, cancel a VGA computer display, on software, adopt interface menu and picture overlapping.

The embodiment of the invention is described in detail in conjunction with the accompanying drawings.

Fig. 1 is a pathology work station main body collocation method wiring diagram of the present invention;

Fig. 2 is a biological sample microscopic image analytical system wiring diagram of the present invention;

Fig. 3 forked working of the present invention station user disposes wiring diagram;

Fig. 4 is CCD photographic head binocular twoport lens barrel structure figure;

Fig. 5 is CCD photographic head twoport lens barrel structure figure.

The present invention adopts 256 grades of gray scale illumination biological microscopies, 5 configuration binocular twoport lens barrels 3 as shown in Figure 4, or configuration twoport lens barrel 16 as shown in Figure 5, black-white CCD photographic head 4 and colored CCD photographic head 1 are installed as shown in Figure 1 respectively on lens barrel, be equipped with in colored CCD photographic head 1 interface contract at 1: 0.5 than video-frequency connector 2 form microscope camera systems, wherein colored CCD photographic head 1 is connected work station foreground PC main frame 6 respectively with black-white CCD photographic head 4, main frame 6 (is the 16M internal memory, special-purpose dual pathways image processing card) connects work station background server 11 (PC main frame 16M internal memories, NOVELL net environment configurations and MODEM address card) and VGA display 12, above-mentioned work station background server 11 connects giant-screen high-resolution color image diplay 8 respectively, color jet-ink or colored heat sublimation printer 9, telephone set 13 and facsimile machine 10, UPS uninterrupted power source 14 is set in addition, and black and white and colored CCD photographic head 4 and 1 and microscope 5 by power supply 7 power supply.

Background server 11, VGA color display 12, telephone set 13, facsimile machine 10 are removed in the body of work station, as shown in Figure 2, main frame 6 outputs connect color image display device 8 and printer 9 is formed living specimen microscopic image analytical system, other connection is identical with Fig. 1, black and white is connected main frame 6 with colored stylus 4 respectively with 1, and power supply 7 is for the microscope power supply of quantitatively throwing light on of black and white and colored CCD photographic head and 256 grades of gray scales.

By PC main frame 11 (16M internal memory, NOVELL network interface card, MODEM card) be connected with telephone set 13, colour or black and white ink-jet printer 15, color image display device 17, UPS uninterrupted power source 14 as shown in Figure 3 as, form the forked working station.

Body of work station foreground host in the above-mentioned whole system mainly is to bear various image processings and analyzing and testing function, background server is to bear file administration, the data base, multiple expanded functions such as picture and text communication transmission, build the NOVELL environment configurations with the forked working station, cross telephone wire by the MODEM cartoon and go into the INTERNET net, internally equally by telephone wire and switch networking, the forked working station is controlled and can independently enjoy obtaining of network transmission and teledata, therefore, the scientific research of pathology, education, routine analysis detects, the pathology management, remote medical consultation with specialists all can be finished by the present invention.

Claims

1, a kind of by biological microscope, the CCD photographic head, the high-performance power supply, PC, the composing method of the pathology workstation system that image diplay and printer are formed, it is characterized in that by adopting 256 grades of gray scale illumination biological microscopies (5) to mix binocular twoport lens barrel (3), black and white and colored CCD photographic head (4) and (1) are installed on lens barrel respectively, be equipped with in colored CCD photographic head (1) interface contract at 1: 0.5 than video-frequency connector (2) form microscope camera system, wherein colored CCD photographic head (1) is connected foreground, body of work station PC main frame (6) respectively with black-white CCD photographic head (4), main frame (6) connects background server (11) and VGA display (12), above-mentioned background server (11) connects giant-screen high-resolution color image diplay (8) respectively, color jet-ink or colored heat sublimation printer (9), telephone set (13) and facsimile machine (10), UPS uninterrupted power source (14) is set in addition, and power supply (7) connects black and white (4) and colored CCD (1) and microscope (5) respectively.

2, the composing method of pathology work workstation system according to claim 1, it is characterized in that the black-white CCD photographic head (4) in the microscope camera system is connected PC main frame (6) main frame (6) respectively with colour imagery shot (1), the outfan of main frame (6) connects color image display device (8) respectively and printer (9) is formed biological sample microscopic image analytical system.

3, the composing method of pathology workstation system according to claim 1, it is characterized in that by PC main frame (11) answer the call machine (13) and colour or black and white ink-jet printer (15) and color image display device (17), and establish UPS uninterrupted power source (14).Form the forked working station.