CN118510801A - 用于多发性骨髓瘤的靶向bcma的car-t细胞疗法 - Google Patents

用于多发性骨髓瘤的靶向bcma的car-t细胞疗法 Download PDF

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Publication number
CN118510801A
CN118510801A CN202280073251.5A CN202280073251A CN118510801A CN 118510801 A CN118510801 A CN 118510801A CN 202280073251 A CN202280073251 A CN 202280073251A CN 118510801 A CN118510801 A CN 118510801A
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cells
car
effective
administration
response
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CN202280073251.5A
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Chinese (zh)
Inventor
穆罕默德·阿克拉姆
凯文·德布拉甘卡
范晓虎
耿东
托尼娅·内谢瓦特
莉达·帕考德
乔丹·谢克特
海伦·瓦索斯
恩里克·苏代雷乌巴尼
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Legendary Biotechnology Usa
Nanjing Legend Biotechnology Co Ltd
Janssen Biotech Inc
Original Assignee
Legendary Biotechnology Usa
Nanjing Legend Biotechnology Co Ltd
Janssen Biotech Inc
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Priority claimed from PCT/CN2021/128578 external-priority patent/WO2023077343A1/en
Application filed by Legendary Biotechnology Usa, Nanjing Legend Biotechnology Co Ltd, Janssen Biotech Inc filed Critical Legendary Biotechnology Usa
Publication of CN118510801A publication Critical patent/CN118510801A/zh
Pending legal-status Critical Current

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CN202280073251.5A 2021-11-04 2022-11-03 用于多发性骨髓瘤的靶向bcma的car-t细胞疗法 Pending CN118510801A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163275471P 2021-11-04 2021-11-04
CNPCT/CN2021/128578 2021-11-04
US63/275,471 2021-11-04
PCT/CN2021/128578 WO2023077343A1 (en) 2021-11-04 2021-11-04 Bcma-targeted car-t cell therapy for multiple myeloma
PCT/US2022/079216 WO2023081752A1 (en) 2021-11-04 2022-11-03 Bcma-targeted car-t cell therapy for multiple myeloma

Publications (1)

Publication Number Publication Date
CN118510801A true CN118510801A (zh) 2024-08-16

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CN202280073251.5A Pending CN118510801A (zh) 2021-11-04 2022-11-03 用于多发性骨髓瘤的靶向bcma的car-t细胞疗法

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US (1) US20230277589A1 (https=)
EP (1) EP4426737A1 (https=)
JP (1) JP2024540275A (https=)
KR (1) KR20240117530A (https=)
CN (1) CN118510801A (https=)
AU (1) AU2022381186A1 (https=)
CA (1) CA3237341A1 (https=)
IL (1) IL312602A (https=)
JO (1) JOP20240104A1 (https=)
MX (1) MX2024005461A (https=)
WO (1) WO2023081752A1 (https=)

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AU2020378263A1 (en) 2019-11-05 2022-06-23 Janssen Biotech, Inc. BCMA-targeted CAR-T cell therapy of multiple myeloma
WO2025006799A1 (en) 2023-06-27 2025-01-02 Capstan Therapeutics, Inc. Extracorporeal and ex vivo engineering of select cell populations from peripheral blood
WO2025076341A1 (en) * 2023-10-05 2025-04-10 Janssen Biotech, Inc. Improved methods in lentiviral manufacturing for production of car-t cell drug products
WO2025096878A1 (en) 2023-11-02 2025-05-08 Capstan Therapeutics, Inc. Rna for in vivo transfection with increased expression
US20250269024A1 (en) * 2024-02-05 2025-08-28 Legend Biotech Usa Inc. Bcma-targeted car-t cell therapy for multiple myeloma
WO2026072671A1 (en) 2024-09-24 2026-04-02 City Of Hope Methods comprising oncolytic viruses expressing bcmat and bcma-targeted therapies

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