CN118510507A - 用于治疗抑郁症的组合物和方法 - Google Patents

用于治疗抑郁症的组合物和方法 Download PDF

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Publication number
CN118510507A
CN118510507A CN202380016647.0A CN202380016647A CN118510507A CN 118510507 A CN118510507 A CN 118510507A CN 202380016647 A CN202380016647 A CN 202380016647A CN 118510507 A CN118510507 A CN 118510507A
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CN
China
Prior art keywords
level
patient
dynorphin
treatment
identified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202380016647.0A
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English (en)
Chinese (zh)
Inventor
W·C·德瑞维茨
H·C·科尔布
Z·S·萨阿德
T·王
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of CN118510507A publication Critical patent/CN118510507A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN202380016647.0A 2022-01-10 2023-01-09 用于治疗抑郁症的组合物和方法 Pending CN118510507A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263298047P 2022-01-10 2022-01-10
US63/298047 2022-01-10
PCT/IB2023/050170 WO2023131920A1 (en) 2022-01-10 2023-01-09 Compositions and methods for the treatment of depression

Publications (1)

Publication Number Publication Date
CN118510507A true CN118510507A (zh) 2024-08-16

Family

ID=84981555

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202380016647.0A Pending CN118510507A (zh) 2022-01-10 2023-01-09 用于治疗抑郁症的组合物和方法

Country Status (10)

Country Link
US (1) US20250221960A1 (https=)
EP (1) EP4463152A1 (https=)
JP (1) JP2025503646A (https=)
KR (1) KR20240132479A (https=)
CN (1) CN118510507A (https=)
AU (1) AU2023205471A1 (https=)
CA (1) CA3247760A1 (https=)
IL (1) IL314179A (https=)
MX (1) MX2024008618A (https=)
WO (1) WO2023131920A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024336807A1 (en) * 2023-09-06 2026-04-16 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant for use in treating major depressive disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト

Also Published As

Publication number Publication date
EP4463152A1 (en) 2024-11-20
JP2025503646A (ja) 2025-02-04
KR20240132479A (ko) 2024-09-03
WO2023131920A1 (en) 2023-07-13
IL314179A (en) 2024-09-01
CA3247760A1 (en) 2023-07-13
US20250221960A1 (en) 2025-07-10
AU2023205471A1 (en) 2024-08-29
MX2024008618A (es) 2024-09-25

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