CA3247760A1 - Compositions and methods of treating depression - Google Patents

Compositions and methods of treating depression

Info

Publication number
CA3247760A1
CA3247760A1 CA3247760A CA3247760A CA3247760A1 CA 3247760 A1 CA3247760 A1 CA 3247760A1 CA 3247760 A CA3247760 A CA 3247760A CA 3247760 A CA3247760 A CA 3247760A CA 3247760 A1 CA3247760 A1 CA 3247760A1
Authority
CA
Canada
Prior art keywords
level
aticaprant
treatment
patient
dynorphin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3247760A
Other languages
English (en)
French (fr)
Inventor
Wayne C. Drevets
Hartmuth Christian Kolb
Ziad Serhal SAAD
Tina Wang
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of CA3247760A1 publication Critical patent/CA3247760A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3247760A 2022-01-10 2023-01-09 Compositions and methods of treating depression Pending CA3247760A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263298047P 2022-01-10 2022-01-10
US63/298,047 2022-01-10
PCT/IB2023/050170 WO2023131920A1 (en) 2022-01-10 2023-01-09 Compositions and methods for the treatment of depression

Publications (1)

Publication Number Publication Date
CA3247760A1 true CA3247760A1 (en) 2023-07-13

Family

ID=84981555

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3247760A Pending CA3247760A1 (en) 2022-01-10 2023-01-09 Compositions and methods of treating depression

Country Status (10)

Country Link
US (1) US20250221960A1 (https=)
EP (1) EP4463152A1 (https=)
JP (1) JP2025503646A (https=)
KR (1) KR20240132479A (https=)
CN (1) CN118510507A (https=)
AU (1) AU2023205471A1 (https=)
CA (1) CA3247760A1 (https=)
IL (1) IL314179A (https=)
MX (1) MX2024008618A (https=)
WO (1) WO2023131920A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024336807A1 (en) * 2023-09-06 2026-04-16 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant for use in treating major depressive disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト

Also Published As

Publication number Publication date
EP4463152A1 (en) 2024-11-20
CN118510507A (zh) 2024-08-16
JP2025503646A (ja) 2025-02-04
KR20240132479A (ko) 2024-09-03
WO2023131920A1 (en) 2023-07-13
IL314179A (en) 2024-09-01
US20250221960A1 (en) 2025-07-10
AU2023205471A1 (en) 2024-08-29
MX2024008618A (es) 2024-09-25

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