CN118434281A - 用于异种移植的包含十个基因修饰的多转基因猪 - Google Patents

用于异种移植的包含十个基因修饰的多转基因猪 Download PDF

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CN118434281A
CN118434281A CN202280077086.0A CN202280077086A CN118434281A CN 118434281 A CN118434281 A CN 118434281A CN 202280077086 A CN202280077086 A CN 202280077086A CN 118434281 A CN118434281 A CN 118434281A
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promoter
transgene
transgenes
human
cagpr
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M·科基纳基
K·V·库拉维
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Revivicor Inc
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CN202280077086.0A 2021-09-20 2022-09-19 用于异种移植的包含十个基因修饰的多转基因猪 Pending CN118434281A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163261393P 2021-09-20 2021-09-20
US63/261,393 2021-09-20
PCT/US2022/043967 WO2023044100A1 (en) 2021-09-20 2022-09-19 Multitran scenic pigs comprising ten genetic modifications for xenotransplantation

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CN118434281A true CN118434281A (zh) 2024-08-02

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US (1) US20230255185A1 (https=)
EP (1) EP4404740A1 (https=)
JP (1) JP2024534702A (https=)
KR (1) KR20240099180A (https=)
CN (1) CN118434281A (https=)
AU (1) AU2022347161A1 (https=)
CA (1) CA3232376A1 (https=)
IL (1) IL311538A (https=)
WO (1) WO2023044100A1 (https=)

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Publication number Priority date Publication date Assignee Title
WO2025012119A1 (en) * 2023-07-07 2025-01-16 Technische Universitaet Muenchen Transgenic pig comprising a transgene for xenotransplantation
WO2025226936A1 (en) 2024-04-24 2025-10-30 Revivicor, Inc. Donor-specific tolerance-inducing regimens for xenotransplantation

Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2017044864A1 (en) * 2015-09-09 2017-03-16 Revivicor, Inc Multi-transgenic pig for xenotransplantation
WO2019185936A2 (en) * 2018-03-29 2019-10-03 Bruno Reichart Methods and compositions for prolonging the survival after orthotopic and heterotopic xenogeneic heart, kidney, lung or liver transplantations

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