CN118415179A - Pesticide composition containing prothioconazole, carboxin and cartap and application thereof - Google Patents
Pesticide composition containing prothioconazole, carboxin and cartap and application thereof Download PDFInfo
- Publication number
- CN118415179A CN118415179A CN202410523693.6A CN202410523693A CN118415179A CN 118415179 A CN118415179 A CN 118415179A CN 202410523693 A CN202410523693 A CN 202410523693A CN 118415179 A CN118415179 A CN 118415179A
- Authority
- CN
- China
- Prior art keywords
- agent
- cartap
- carboxin
- prothioconazole
- percent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- IRUJZVNXZWPBMU-UHFFFAOYSA-N cartap Chemical compound NC(=O)SCC(N(C)C)CSC(N)=O IRUJZVNXZWPBMU-UHFFFAOYSA-N 0.000 title claims abstract description 193
- MNHVNIJQQRJYDH-UHFFFAOYSA-N 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione Chemical compound N1=CNC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl MNHVNIJQQRJYDH-UHFFFAOYSA-N 0.000 title claims abstract description 155
- 239000005825 Prothioconazole Substances 0.000 title claims abstract description 155
- 239000005746 Carboxin Substances 0.000 title claims abstract description 154
- GYSSRZJIHXQEHQ-UHFFFAOYSA-N carboxin Chemical compound S1CCOC(C)=C1C(=O)NC1=CC=CC=C1 GYSSRZJIHXQEHQ-UHFFFAOYSA-N 0.000 title claims abstract description 154
- 239000000575 pesticide Substances 0.000 title claims abstract description 78
- 239000000203 mixture Substances 0.000 title claims abstract description 67
- 241000209094 Oryza Species 0.000 claims abstract description 147
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 147
- 235000009566 rice Nutrition 0.000 claims abstract description 146
- 201000010099 disease Diseases 0.000 claims abstract description 133
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 133
- 238000005728 strengthening Methods 0.000 claims abstract description 20
- 239000004480 active ingredient Substances 0.000 claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 98
- 239000004563 wettable powder Substances 0.000 claims description 66
- 238000011282 treatment Methods 0.000 claims description 64
- 239000002270 dispersing agent Substances 0.000 claims description 28
- 239000000945 filler Substances 0.000 claims description 22
- 239000003381 stabilizer Substances 0.000 claims description 22
- 239000000080 wetting agent Substances 0.000 claims description 22
- 230000000149 penetrating effect Effects 0.000 claims description 19
- 239000000843 powder Substances 0.000 claims description 18
- 241000294569 Aphelenchoides Species 0.000 claims description 15
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical group [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 12
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical group CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- 239000005995 Aluminium silicate Substances 0.000 claims description 6
- 229910000503 Na-aluminosilicate Inorganic materials 0.000 claims description 6
- 235000012211 aluminium silicate Nutrition 0.000 claims description 6
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 6
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical group [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 claims description 6
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical group [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 claims description 6
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical group O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 6
- 229930187593 rose bengal Natural products 0.000 claims description 6
- 229940081623 rose bengal Drugs 0.000 claims description 6
- STRXNPAVPKGJQR-UHFFFAOYSA-N rose bengal A Natural products O1C(=O)C(C(=CC=C2Cl)Cl)=C2C21C1=CC(I)=C(O)C(I)=C1OC1=C(I)C(O)=C(I)C=C21 STRXNPAVPKGJQR-UHFFFAOYSA-N 0.000 claims description 6
- 239000000429 sodium aluminium silicate Substances 0.000 claims description 6
- 235000012217 sodium aluminium silicate Nutrition 0.000 claims description 6
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical group [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 claims description 6
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 claims description 6
- 230000007480 spreading Effects 0.000 claims description 6
- 238000003892 spreading Methods 0.000 claims description 6
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 5
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 5
- 150000005215 alkyl ethers Chemical class 0.000 claims description 5
- 239000012752 auxiliary agent Substances 0.000 claims description 5
- 239000000440 bentonite Substances 0.000 claims description 5
- 229910000278 bentonite Inorganic materials 0.000 claims description 5
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical group O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 5
- 235000012730 carminic acid Nutrition 0.000 claims description 5
- -1 polyoxyethylene Polymers 0.000 claims description 5
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 5
- 239000000377 silicon dioxide Substances 0.000 claims description 5
- 239000011734 sodium Substances 0.000 claims description 5
- 229910052708 sodium Inorganic materials 0.000 claims description 5
- 239000000230 xanthan gum Substances 0.000 claims description 5
- 229920001285 xanthan gum Polymers 0.000 claims description 5
- 229940082509 xanthan gum Drugs 0.000 claims description 5
- 235000010493 xanthan gum Nutrition 0.000 claims description 5
- 235000012239 silicon dioxide Nutrition 0.000 claims description 4
- FWVCSXWHVOOTFJ-UHFFFAOYSA-N 1-(2-chloroethylsulfanyl)-2-[2-(2-chloroethylsulfanyl)ethoxy]ethane Chemical compound ClCCSCCOCCSCCCl FWVCSXWHVOOTFJ-UHFFFAOYSA-N 0.000 claims description 3
- 230000000295 complement effect Effects 0.000 claims description 3
- IICCLYANAQEHCI-UHFFFAOYSA-N 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one Chemical group O1C(=O)C(C(=C(Cl)C(Cl)=C2Cl)Cl)=C2C21C1=CC(I)=C(O)C(I)=C1OC1=C(I)C(O)=C(I)C=C21 IICCLYANAQEHCI-UHFFFAOYSA-N 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 74
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 19
- 239000003899 bactericide agent Substances 0.000 abstract description 16
- 239000005820 Prochloraz Substances 0.000 abstract description 15
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 abstract description 15
- 241000918585 Pythium aphanidermatum Species 0.000 abstract description 13
- 150000001875 compounds Chemical class 0.000 abstract description 12
- 206010059866 Drug resistance Diseases 0.000 abstract description 10
- 230000001737 promoting effect Effects 0.000 abstract description 10
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 abstract description 8
- 239000006013 carbendazim Substances 0.000 abstract description 8
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 abstract description 8
- 238000001228 spectrum Methods 0.000 abstract description 7
- 230000002195 synergetic effect Effects 0.000 abstract description 7
- 241000134843 Aphelenchoides besseyi Species 0.000 abstract description 6
- 238000011161 development Methods 0.000 abstract description 6
- 230000009471 action Effects 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 5
- 230000007246 mechanism Effects 0.000 abstract description 3
- 239000005776 Fenhexamid Substances 0.000 abstract description 2
- VDLGAVXLJYLFDH-UHFFFAOYSA-N fenhexamid Chemical compound C=1C=C(O)C(Cl)=C(Cl)C=1NC(=O)C1(C)CCCCC1 VDLGAVXLJYLFDH-UHFFFAOYSA-N 0.000 abstract description 2
- 230000002452 interceptive effect Effects 0.000 abstract description 2
- 239000005645 nematicide Substances 0.000 abstract description 2
- 238000002360 preparation method Methods 0.000 description 96
- 239000003814 drug Substances 0.000 description 52
- 239000007788 liquid Substances 0.000 description 37
- 238000012360 testing method Methods 0.000 description 29
- 241000196324 Embryophyta Species 0.000 description 26
- 238000000034 method Methods 0.000 description 21
- 230000002265 prevention Effects 0.000 description 18
- 241000244206 Nematoda Species 0.000 description 15
- 238000013329 compounding Methods 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- 241000223218 Fusarium Species 0.000 description 11
- 230000008901 benefit Effects 0.000 description 11
- ZNOLGFHPUIJIMJ-UHFFFAOYSA-N fenitrothion Chemical compound COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C(C)=C1 ZNOLGFHPUIJIMJ-UHFFFAOYSA-N 0.000 description 11
- 238000004519 manufacturing process Methods 0.000 description 11
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 10
- 235000013339 cereals Nutrition 0.000 description 10
- 230000012010 growth Effects 0.000 description 10
- 244000184734 Pyrus japonica Species 0.000 description 9
- 241000607479 Yersinia pestis Species 0.000 description 9
- 244000052616 bacterial pathogen Species 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 239000002689 soil Substances 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- 229940079593 drug Drugs 0.000 description 8
- 238000012545 processing Methods 0.000 description 7
- 238000011160 research Methods 0.000 description 7
- 238000004659 sterilization and disinfection Methods 0.000 description 7
- 241000233866 Fungi Species 0.000 description 6
- 241000238631 Hexapoda Species 0.000 description 6
- 239000003337 fertilizer Substances 0.000 description 6
- 238000011835 investigation Methods 0.000 description 6
- 238000005070 sampling Methods 0.000 description 6
- 230000001954 sterilising effect Effects 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000018109 developmental process Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 5
- 230000002147 killing effect Effects 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- AZJPTIGZZTZIDR-UHFFFAOYSA-L rose bengal Chemical group [K+].[K+].[O-]C(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C1=C2C=C(I)C(=O)C(I)=C2OC2=C(I)C([O-])=C(I)C=C21 AZJPTIGZZTZIDR-UHFFFAOYSA-L 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 241000283973 Oryctolagus cuniculus Species 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 230000035558 fertility Effects 0.000 description 4
- 239000005416 organic matter Substances 0.000 description 4
- 230000000361 pesticidal effect Effects 0.000 description 4
- 238000009700 powder processing Methods 0.000 description 4
- 230000009467 reduction Effects 0.000 description 4
- 150000003839 salts Chemical group 0.000 description 4
- 238000002791 soaking Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241001220430 Aphelenchus Species 0.000 description 3
- LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 3
- 239000005789 Folpet Substances 0.000 description 3
- 241000221778 Fusarium fujikuroi Species 0.000 description 3
- 241001330975 Magnaporthe oryzae Species 0.000 description 3
- 208000031888 Mycoses Diseases 0.000 description 3
- 241000529915 Xylophilus Species 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 229960003168 bronopol Drugs 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- ZXQYGBMAQZUVMI-UNOMPAQXSA-N cyhalothrin Chemical compound CC1(C)C(\C=C(/Cl)C(F)(F)F)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-UNOMPAQXSA-N 0.000 description 3
- 230000017858 demethylation Effects 0.000 description 3
- 238000010520 demethylation reaction Methods 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- HKIOYBQGHSTUDB-UHFFFAOYSA-N folpet Chemical compound C1=CC=C2C(=O)N(SC(Cl)(Cl)Cl)C(=O)C2=C1 HKIOYBQGHSTUDB-UHFFFAOYSA-N 0.000 description 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 3
- 239000003112 inhibitor Substances 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 230000035882 stress Effects 0.000 description 3
- 230000009885 systemic effect Effects 0.000 description 3
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 2
- 241000223195 Fusarium graminearum Species 0.000 description 2
- 239000005794 Hymexazol Substances 0.000 description 2
- 241001361634 Rhizoctonia Species 0.000 description 2
- 239000005929 Spinetoram Substances 0.000 description 2
- GOENIMGKWNZVDA-OAMCMWGQSA-N Spinetoram Chemical compound CO[C@@H]1[C@H](OCC)[C@@H](OC)[C@H](C)O[C@H]1OC1C[C@H]2[C@@H]3C=C4C(=O)[C@H](C)[C@@H](O[C@@H]5O[C@H](C)[C@H](CC5)N(C)C)CCC[C@H](CC)OC(=O)CC4[C@@H]3CC[C@@H]2C1 GOENIMGKWNZVDA-OAMCMWGQSA-N 0.000 description 2
- 229930182558 Sterol Natural products 0.000 description 2
- 241000082085 Verticillium <Phyllachorales> Species 0.000 description 2
- 241001464837 Viridiplantae Species 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 125000004802 cyanophenyl group Chemical group 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000001066 destructive effect Effects 0.000 description 2
- 230000006806 disease prevention Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- IXORZMNAPKEEDV-OBDJNFEBSA-N gibberellin A3 Chemical compound C([C@@]1(O)C(=C)C[C@@]2(C1)[C@H]1C(O)=O)C[C@H]2[C@]2(C=C[C@@H]3O)[C@H]1[C@]3(C)C(=O)O2 IXORZMNAPKEEDV-OBDJNFEBSA-N 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- KGVPNLBXJKTABS-UHFFFAOYSA-N hymexazol Chemical compound CC1=CC(O)=NO1 KGVPNLBXJKTABS-UHFFFAOYSA-N 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000000749 insecticidal effect Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- DSOOGBGKEWZRIH-UHFFFAOYSA-N nereistoxin Chemical compound CN(C)C1CSSC1 DSOOGBGKEWZRIH-UHFFFAOYSA-N 0.000 description 2
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 2
- 230000000243 photosynthetic effect Effects 0.000 description 2
- 229940002612 prodrug Drugs 0.000 description 2
- 239000000651 prodrug Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000007226 seed germination Effects 0.000 description 2
- 150000003432 sterols Chemical class 0.000 description 2
- 235000003702 sterols Nutrition 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 150000003852 triazoles Chemical class 0.000 description 2
- 238000004383 yellowing Methods 0.000 description 2
- BQPPJGMMIYJVBR-UHFFFAOYSA-N (10S)-3c-Acetoxy-4.4.10r.13c.14t-pentamethyl-17c-((R)-1.5-dimethyl-hexen-(4)-yl)-(5tH)-Delta8-tetradecahydro-1H-cyclopenta[a]phenanthren Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C BQPPJGMMIYJVBR-UHFFFAOYSA-N 0.000 description 1
- CHGIKSSZNBCNDW-UHFFFAOYSA-N (3beta,5alpha)-4,4-Dimethylcholesta-8,24-dien-3-ol Natural products CC12CCC(O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21 CHGIKSSZNBCNDW-UHFFFAOYSA-N 0.000 description 1
- XYTLYKGXLMKYMV-UHFFFAOYSA-N 14alpha-methylzymosterol Natural products CC12CCC(O)CC1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C XYTLYKGXLMKYMV-UHFFFAOYSA-N 0.000 description 1
- FPTJELQXIUUCEY-UHFFFAOYSA-N 3beta-Hydroxy-lanostan Natural products C1CC2C(C)(C)C(O)CCC2(C)C2C1C1(C)CCC(C(C)CCCC(C)C)C1(C)CC2 FPTJELQXIUUCEY-UHFFFAOYSA-N 0.000 description 1
- 241001578974 Achlya <moth> Species 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 241001022589 Fusarium andiyazi Species 0.000 description 1
- 241000690372 Fusarium proliferatum Species 0.000 description 1
- 241000233732 Fusarium verticillioides Species 0.000 description 1
- BKLIAINBCQPSOV-UHFFFAOYSA-N Gluanol Natural products CC(C)CC=CC(C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(O)C(C)(C)C4CC3 BKLIAINBCQPSOV-UHFFFAOYSA-N 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- 241000223198 Humicola Species 0.000 description 1
- LOPKHWOTGJIQLC-UHFFFAOYSA-N Lanosterol Natural products CC(CCC=C(C)C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(C)(O)C(C)(C)C4CC3 LOPKHWOTGJIQLC-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 1
- 206010028400 Mutagenic effect Diseases 0.000 description 1
- 231100000678 Mycotoxin Toxicity 0.000 description 1
- 101710204026 Myosin-5 Proteins 0.000 description 1
- CAHGCLMLTWQZNJ-UHFFFAOYSA-N Nerifoliol Natural products CC12CCC(O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C CAHGCLMLTWQZNJ-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 239000005822 Propiconazole Substances 0.000 description 1
- 241000233639 Pythium Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 241001420287 Strobilanthes maculata Species 0.000 description 1
- 229940122840 Succinic dehydrogenase inhibitor Drugs 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 244000250129 Trigonella foenum graecum Species 0.000 description 1
- 235000001484 Trigonella foenum graecum Nutrition 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000001887 anti-feedant effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- SKOLWUPSYHWYAM-UHFFFAOYSA-N carbonodithioic O,S-acid Chemical compound SC(S)=O SKOLWUPSYHWYAM-UHFFFAOYSA-N 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000007405 data analysis Methods 0.000 description 1
- QBSJHOGDIUQWTH-UHFFFAOYSA-N dihydrolanosterol Natural products CC(C)CCCC(C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(C)(O)C(C)(C)C4CC3 QBSJHOGDIUQWTH-UHFFFAOYSA-N 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- XJLZCPIILZRCPS-ANMPWZFDSA-N eburicol Chemical group C([C@@]12C)C[C@H](O)C(C)(C)[C@@H]1CCC1=C2CC[C@]2(C)[C@@H]([C@H](C)CCC(=C)C(C)C)CC[C@]21C XJLZCPIILZRCPS-ANMPWZFDSA-N 0.000 description 1
- 230000001999 effect on insects Effects 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 230000008686 ergosterol biosynthesis Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003008 fumonisin Substances 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- IXORZMNAPKEEDV-UHFFFAOYSA-N gibberellic acid GA3 Natural products OC(=O)C1C2(C3)CC(=C)C3(O)CCC2C2(C=CC3O)C1C3(C)C(=O)O2 IXORZMNAPKEEDV-UHFFFAOYSA-N 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 208000027407 head symptom Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 231100000171 higher toxicity Toxicity 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 208000006278 hypochromic anemia Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 239000003621 irrigation water Substances 0.000 description 1
- CAHGCLMLTWQZNJ-RGEKOYMOSA-N lanosterol Chemical group C([C@]12C)C[C@@H](O)C(C)(C)[C@H]1CCC1=C2CC[C@]2(C)[C@H]([C@H](CCC=C(C)C)C)CC[C@@]21C CAHGCLMLTWQZNJ-RGEKOYMOSA-N 0.000 description 1
- 229940058690 lanosterol Drugs 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 210000003470 mitochondria Anatomy 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 231100000243 mutagenic effect Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 239000002636 mycotoxin Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000005080 plant death Effects 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 230000002786 root growth Effects 0.000 description 1
- 230000035040 seed growth Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 231100000378 teratogenic Toxicity 0.000 description 1
- 230000003390 teratogenic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012876 topography Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- QPDUQKTYZRXRBC-UHFFFAOYSA-N triazole-4-thione Chemical compound S=C1C=NN=N1 QPDUQKTYZRXRBC-UHFFFAOYSA-N 0.000 description 1
- 235000001019 trigonella foenum-graecum Nutrition 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a pesticide composition containing prothioconazole, carboxin and cartap and application thereof, which comprises the active ingredients of prothioconazole, carboxin and cartap, wherein the mass ratio of the prothioconazole and carboxin with bactericidal activity to the cartap with nematicide activity is 1-15:1-10. The pesticide composition has various effective component action mechanisms, no interactive resistance, good physical and chemical compatibility, practical registration and development, expands the control spectrum, has remarkable synergistic effect, can effectively treat the drug resistance of bakanae disease germ of rice to bactericides such as carbendazim, prochloraz, fenhexamid and the like, cultivates strong seedlings, and has great application value for improving the yield and quality of rice. The compound pesticide has excellent and obvious effect on preventing and controlling bakanae disease, arthamartopathy, damping-off disease and aphelenchoides besseyi disease of rice, has obvious effect of promoting root and strengthening seedling, has obvious effect of reducing pesticide and strengthening seedling, has excellent and low quality, is environment-friendly and safe, and has wide market prospect.
Description
Technical Field
The invention relates to the field of pesticide compositions, in particular to a pesticide composition containing prothioconazole, carboxin and cartap.
Background
Rice (Oryza sativa l.) is the world's second largest food crop next to wheat and is also the main food crop in excess of 30 million people worldwide. In rice production, serious yield losses are caused by diseases, insect pests and grass pests, in particular fungal diseases. Rice bakanae disease (rice bakanae disease) caused by 4 pathogenic bacteria of Fusarium vine (Fusariumfujikuroi), fusarium layering (F. Proliferatum), fusarium verticillium (F. Verticillioides), and Fusarium neoknown (F. Andiyazi) is a destructive seed-borne disease, wherein Fusarium vine [ has the behavior: gibberella fumosoroseus (Gibberellafujikuroi) is the most common pathogenic species. Pathogenic bacteria are mainly attached to the surface of seeds by conidium, mycelia are hidden on the seeds or disease straws for overwintering, and the seed with the bacteria is the primary infection source for bakanae disease; the bakanae disease can affect rice plants from the pre-emergence stage to the mature stage of the rice, and three incidence peaks generally appear in the seedling stage, the tillering stage and the jointing booting stage. The rice victim plant usually shows slender and overgrown plants, and has typical symptoms of long, thin, chlorosis and yellowing leaves, sterile grains, color change and the like; severely infected seedlings usually die at an early stage, sometimes the disease symptoms of the seedlings infected by germs disappear after field transplanting, but reappear after the tillering stage, ultimately leading to plant death or poor grain filling or empty and shrunken. Bakanae disease seriously threatens the safe production of rice worldwide, causes the yield reduction of rice at different degrees, even is out of harvest, and can also cause the pollution of mycotoxins such as fumonisin, gibberellin A3 and the like of harvested rice to threaten the health of human beings and animals.
For many years, bactericides are widely used for treating rice seed medicines in order to effectively prevent and treat bakanae disease, but the efficacy is greatly reduced or even disabled due to the drug resistance of germs to the bactericides. In China, benzimidazole bactericides, especially carbendazim, are mainly used in seventies of the last century, and the benzimidazole bactericides begin to be used for controlling bakanae disease, have remarkable medicinal effects and are gradually and widely applied. Due to the continuous single broad application of carbendazim, in 1992, fusarium graminearum was found to be resistant to carbendazim. The imidazole bactericide prochloraz is widely used for preventing and treating bakanae disease, has obvious field prevention effect, and then a great deal of researches report that bakanae bacteria generate drug resistance to prochloraz to cause the decrease of the prevention effect of the drug. The novel bactericide, namely cyanoacrylate bactericide cyanophenyl which is independently created in 1998 by Jiangsu province pesticide institute, is a novel bactericide with a fusarium specific action mode, can effectively inhibit fusarium conidium germination and hypha growth, interfere the function of fusarium myosin-5, has excellent bakanae disease prevention effect, but has been found in 2016 that fusarium graminearum strains in Zhejiang province produce drug resistance to cyanophenyl. The bakanae germ in Jiangsu province has different degrees of drug resistance to carbendazim, prochloraz and cyhalothrin, and has an expanded state of drug resistance to the cyhalothrin which is popularized and applied in the field for less than 10 years; in the production of rice in Jiangsu province, the single use of carbendazim, prochloraz or fenhexamid for preventing and treating bakanae disease is lost. Up to 4 months in 2024, the agricultural and rural pesticide verification institute of China formally registers more than 200 medicaments for preventing and treating bakanae disease (http:// www.chinapesticide.org.cn/hysj/index. Jhtml), but the number of the active ingredient types of the registered medicaments is less and centralized. Therefore, in the rice production, new agents for preventing and treating bakanae disease need to be optimized and popularized so as to ensure the safe, high-quality and high-efficiency production of the rice.
The rice seedling rot occurs in all rice areas nationally, is a common disease in the rice seedling raising period, occurs to different degrees each year, generally has a death rate of about 15%, has a death rate of field blocks of more than 80%, seriously affects seedling quality, and causes the seedling to be lost when transplanting in the field in part of the areas. Especially in northern rice areas, due to low temperature in early spring, the soil humidity of the seedbed is high, the underground root system of the seedlings is poor in development, and the quality and stress resistance of the seedlings are poor. The rice seedlings can be classified into physiological and infectious types. Physiological rotten seedling refers to diseases caused by purely adverse environmental conditions; the invasive rot seedling is mainly caused by humicola (Achlya spp.), pythium spp, and Fusarium spp. In rice production, the rotted buds and dead seedlings in large areas belong to infectious diseases. The main methods for controlling the rice seedling rot include agricultural control and chemical control. The agricultural control comprises selecting paddy fields with high topography, which are favorable for irrigation and drainage in the sun and wind prevention; selecting rice seeds with high maturity; applying enough base fertilizer, a small amount of additional fertilizer for many times, and the like. The prevention and treatment of the medicament comprises the disinfection of the seedling bed soil, the seed coating treatment and the like. In the medicine control, effective control medicines are screened, and it is important to establish a scientific control method.
The rice seedling blight is mainly a destructive disease of rice in seedling stage caused by fungi such as Fusarium spp and Rhizoctonia spp. The diseased seedlings are withered and yellow and curled, the stem base is separated from the root, and the seedlings are easy to pull out; later stage damage mainly shows core leaf withering and rolling, stem base softening and rot, whole plant yellowing and withering, serious influence on rice seedling quality, and seedling shortage and empty interruption caused during transplanting seriously hinder safe production of rice. The prevention of the disease is mainly carried out by adopting medicaments such as hymexazol and the like for seed treatment. Recently, studies have shown that rice damping-off has reduced sensitivity to agents such as hymexazol. Therefore, effective agents and treatment measures for simultaneously preventing diseases such as bakanae disease and damping off disease of rice are urgently needed to be screened.
The rice aphelenchus xylophilus (Aphelenchoides besseyi Christie) is a plant pathogenic nematode widely spread in rice production areas worldwide, and can cause leaf to generate dry tip symptoms or spike to generate small spike head symptoms after being infected with rice, so that the yield loss of the rice is 10% -30%, and the serious can reach 50%. The nematodes invade plants along with seed germination and rice growth and development and finally enter rice ears for reproduction, after the grains are ripe, the dried nematodes are hidden between glumes of the grains and coiled into a cluster shape, and if the seeds are kept dry, the nematodes can survive for 2-3 years. Researches show that the aphelenchoides can be transferred from variety resources, breeding materials, stock seeds of bred varieties to production seeds along a seed supply chain, and is an important source for causing the aphelenchoides disease of the rice in large-area production. In variety comparison and regional testing, the test material carries the dried aphelenchus xylophilus, which not only affects its own yield performance, but also pollutes other materials of the test base as the nematode propagates with irrigation water. The seed treatment is carried out, and the transfer chain of the aphelenchoides is cut off, so that the method is one of the most economical and efficient control methods for controlling seed-borne diseases such as rice aphelenchoides.
The cultivation of strong seedling is an important measure for high and stable yield of rice. The seedling strengthening agent has the advantages of high physiological activity, strong stress resistance, low dead rate of leaves, strong rooting force, quick turning green, early tillering and obvious early-onset advantage after being transplanted into a field. The cultivation of strong seedling is the foundation of constructing high-yield colony, and the seedling bed of strong seedling has more tillers and can grow early and fast after planting, so that the low-node tillers are more and the tillers are early, which is beneficial to not only ensuring enough spike number, but also forming large spikes, the production of photosynthetic products and the running of the photosynthetic products to the spikes, improving the material yield and the economic coefficient, and forming a high-yield colony with 'early initiation, stable middle stage and no early aging later'. Besides improving the cultivation environment and improving the cultivation technology, the drug seed treatment becomes the most direct and effective method for cultivating strong seedlings, and meanwhile, the drug seed treatment is also an effective way for improving the seed activity and controlling the rice seed-borne diseases. Therefore, the method has important application significance in screening the seed treatment agent with the root and seedling promotion effect.
At present, the above rice bakanae disease, rice seedling rot, rice seedling blight and rice seedling-raising and seedling-strengthening aspects are respectively researched and developed with more related medicaments, but a single seed treatment medicament can effectively prevent and treat the rice bakanae disease, the rice seedling rot, the rice seedling blight and the rice seedling-raising and seedling-strengthening effect.
Disclosure of Invention
The invention aims to: in order to solve the problems in the prior art, the invention provides a pesticide composition containing prothioconazole, carboxin and cartap, which has the advantages of different action mechanisms of active ingredients, no interactive resistance, good physicochemical compatibility, expanded control spectrum and remarkable synergy.
The invention also aims to provide an application of the pesticide composition in preventing and controlling bakanae disease of rice or/and seedling rot of rice or/and seedling blight of rice or/and dry tip nematode disease of rice and in root and seedling promotion of rice.
The technical scheme is as follows: in order to achieve the above purpose, the invention adopts the following technical scheme: a pesticide composition containing prothioconazole, carboxin and cartap comprises the following active ingredients: prothioconazole, carboxin and cartap; the mass ratio of the prothioconazole to the carboxin to the cartap is 1-15:1-10.
Prothioconazole (prothioconazole) is a triazolethione fungicide discovered, developed and produced by bayer crop science, is a sterol demethylation (ergosterol biosynthesis) inhibitor, and acts by inhibiting the demethylation of the 14-position of lanosterol or 24-methylenedihydrolanosterol, a precursor of sterols in fungi, namely, demethylation inhibitor (DMIs). Not only has good systemic activity, excellent protection, treatment and eradication activity, but also has long lasting period. The prothioconazole has excellent prevention effect on almost all fungal diseases on grains, and can be sprayed on leaf surfaces and also used for seed treatment. Through a large number of field efficacy tests, the results show that the prothioconazole has good safety and good disease prevention and treatment effects on crops, and the yield is obviously increased.
The carboxin (carboxin) is a systemic heterocyclic bactericide, is a powerful inhibitor for succinic acid oxidation in germ mitochondria, has a wide sterilization spectrum, has higher toxicity to fungi of basidiomycotina, such as rhizoctonia, black fungus, rust fungus, verticillium in half-known fungus and the like, can infiltrate into germinated seeds to kill germs in the seeds, and has the effects of promoting seed germination and growth.
Cartap (cartap), which is a nereistoxin insecticide, has strong stomach poisoning effect, and simultaneously has the effects of contact killing, certain antifeedant killing, egg killing and the like, and has the advantages of quick knockdown to pests, long residual effect period and broad insecticidal spectrum. No carcinogenic, teratogenic and mutagenic effects are seen. At present, the medicament has an important role in preventing and treating the rice dry-tip nematode disease.
Furthermore, the mass ratio of the prothioconazole to the carboxin to the cartap is 1-5:1-10:1-5; the characteristics of prothioconazole, carboxin and cartap and the screening result of the indoor proportion are combined, and the optimal mass proportion of the ternary combination of prothioconazole, carboxin and cartap is preliminarily determined to be set between 1-5:1-10:1-5.
Furthermore, the mass ratio of the prothioconazole to the carboxin to the cartap is 1:1-4.5:1-2.5.
Furthermore, the pesticide composition also contains an auxiliary agent.
Further, the content of the active ingredient in the pesticidal composition is 10% to 50% by mass, preferably 23% to 32%.
Furthermore, the pesticide composition is in the form of wettable powder or seed treatment dispersible powder.
In some embodiments, for wettable powders, the adjuvant is selected from one or more of a filler, a wetting agent, a dispersing agent, a penetrating agent, a spreader, an anti-caking agent, a stabilizer, a warning color; for the seed treatment dispersible powder, the auxiliary agent is selected from one or more of filler, wetting agent, dispersing agent, penetrating agent, film forming agent, anti-caking agent, stabilizer and color warning agent.
Further, for wettable powders, the filler is selected from kaolin, the wetting agent is selected from sodium lignin sulfonate, the dispersant is selected from dispersant NNO, the penetrating agent is selected from isobutanol, the spreader is selected from sodium dodecyl benzene sulfonate, the anti-caking agent is selected from sodium aluminosilicate, the stabilizer is selected from calcium carbonate, and the warning color is selected from rose bengal.
Further, for seed treatment dispersible powders, the filler is selected from bentonite, the wetting agent is selected from polyoxyethylene alkyl ether, the dispersing agent is selected from sodium alkylbenzenesulfonate, the penetrating agent is selected from penetrating agent T, the film forming agent is selected from xanthan gum, the anti-caking agent is selected from silica, the stabilizing agent is selected from polyvinyl alcohol, and the color warning agent is selected from carmine.
In some embodiments, the wettable powder comprises, in mass percent: 1.5 to 30 percent of prothioconazole, 2 to 22.5 percent of carboxin, 1.5 to 20 percent of cartap, 4 to 7 percent of wetting agent, 2 to 4 percent of dispersing agent, 0.5 to 1 percent of penetrating agent, 1 to 2 percent of spreading agent, 0.6 to 1 percent of anti-caking agent, 0.4 to 0.8 percent of stabilizing agent, 0.1 to 0.5 percent of color warning agent and 100 percent of filler complement; preferably, the wettable powder comprises: 3 to 5 percent of prothioconazole, 8 to 15 percent of carboxin, 8 to 12 percent of cartap, 5 to 6 percent of wetting agent, 2 to 3 percent of dispersing agent, 0.5 to 0.8 percent of penetrating agent, 1 to 1.5 percent of spreading agent, 0.6 to 0.8 percent of anti-caking agent, 0.5 to 0.7 percent of stabilizing agent, 0.2 to 0.5 percent of color warning agent and 100 percent of filler complement; or, the wettable powder comprises: 1 to 2 percent of prothioconazole, 1 to 2 percent of carboxin, 15 to 20 percent of cartap, 5 to 6 percent of wetting agent, 3 to 4 percent of dispersing agent, 0.5 to 1 percent of penetrating agent, 1 to 2 percent of spreading agent, 0.6 to 1 percent of anti-caking agent, 0.5 to 0.8 percent of stabilizing agent, 0.1 to 0.5 percent of color warning agent and 100 percent of filler;
In some embodiments, the seed treatment dispersible powder comprises, in mass percent: 4 to 10 percent of prothioconazole, 10 to 18 percent of carboxin, 6 to 10 percent of cartap, 4 to 5 percent of wetting agent, 4 to 6 percent of dispersing agent, 0.8 to 1 percent of penetrating agent, 1 to 1.5 percent of film forming agent, 0.6 to 1 percent of anti-caking agent, 0.5 to 0.8 percent of stabilizing agent, 0.4 to 0.8 percent of color warning agent and 100 percent of filler; preferably, the seed treatment dispersible powder comprises: 4 to 6 percent of prothioconazole, 10 to 15 percent of carboxin, 8 to 10 percent of cartap, 4.5 to 5 percent of wetting agent, 5 to 6 percent of dispersing agent, 0.9 to 1 percent of penetrating agent, 1 to 1.2 percent of film forming agent, 0.6 to 0.8 percent of anti-caking agent, 0.5 to 0.6 percent of stabilizing agent, 0.4 to 0.6 percent of color warning agent and 100 percent of filler.
The invention also provides application of the pesticide composition in preventing and treating bakanae disease of rice or/and seedling disease of rice or/and damping-off disease of rice or/and dry tip nematode disease of rice.
The invention also provides application of the pesticide composition in root and seedling promotion of rice.
The application comprises: diluting the pesticide composition and soaking seeds.
Further, the rice seed treating agent is diluted 1500-2000 times or 2000-4000 times by water and then soaked. After dilution, the concentration of the active ingredient is 76 to 153. Mu.g/mL, 65 to 130. Mu.g/mL, 75 to 150. Mu.g/mL, or 80 to 160. Mu.g/mL. The seed soaking time is 24-72 h, and is further 36-48 h. The rice variety is salt japonica 456 or/and Wu Yun japonica 24 or/and nan japonica 5718 or/and Shanghai soft 1212.
The beneficial effects are that:
compared with the prior art, the pesticide composition containing prothioconazole, carboxin and cartap has the following advantages:
(1) The original pesticide combination, the product registration and development are feasible: in recent years, along with the issuance and implementation of new policies for pesticide registration in China, higher requirements are put forward on the green and high-quality development of the pesticide industry. The pesticide composition provided by the invention comprises prothioconazole, carboxin and cartap, has different action mechanisms of active ingredients, has no mutual resistance among the components, is good in safety, is an original pesticide composition, can effectively treat the drug resistance of bakanae disease germ of rice to bactericides such as carbendazim, prochloraz and fenugreek, cultivates strong seedlings, and has great application value in improving the yield and quality of rice. The pesticide composition containing prothioconazole, carboxin and cartap accords with the new policy of pesticide registration in China, is feasible to register and develop brand new products, and can provide economic and efficient medicament selection for preventing and treating rice seed-borne or soil-borne diseases such as bakanae disease of rice or/and seedling rot of rice or/and seedling blight of rice or/and dry tip nematode disease of rice in China and promoting root growth and strengthening seedling of rice.
(2) Good mixing property, medicine reduction and synergy: the pH value of the prothioconazole is neutral, and the prothioconazole is stable to hydrolysis when the pH value is 4-9, so that the prothioconazole is a novel bactericide with broad sterilization spectrum, high efficacy, low toxicity, low residue and no environmental risk; carboxin is insoluble in water and is easy to decompose and lose efficacy when meeting alkaline substances; cartap is stable in acidic media and unstable in alkaline media. The pesticide composition containing prothioconazole, carboxin and cartap has good mixing property and good physicochemical compatibility among the components, and is beneficial to preparing high-efficiency stable preparations. The prothioconazole and the carboxin have the function of killing germs, and basically have no control effect on insects; the cartap has higher killing effect on the rice aphelenchus xylophilus, but basically has no control effect on the bakanae disease of rice or/and the arthamartopathy of rice or/and the damping-off disease of rice. The pesticide composition containing prothioconazole, carboxin and cartap can simultaneously prevent and treat bakanae disease of rice or/and seedling blight of rice or/and dry-tip nematode disease of rice, has obvious synergism of sterilization effect and insecticidal effect, has obvious root-promoting and seedling-strengthening effects, can reduce the pesticide dosage, is environment-friendly and safe, and has obvious economic, ecological and social benefits.
(3) The bakanae disease resistance is effectively treated, and the method has great significance for preventing and controlling rice seed-borne or soil-borne diseases: the pesticide composition provided by the invention is compounded by prothioconazole, carboxin and cartap, can effectively treat the drug resistance of bakanae disease germ of rice to bactericides such as carbendazim, prochloraz, cyhalothrin and the like, and can be used alternately with a plurality of existing medicaments; meanwhile, the potential drug resistance of pathogenic bacteria of various rice seed-borne or soil-borne diseases such as bakanae disease or/and rice rot of rice and the like to prothioconazole and carboxin respectively is lightened, the service life of the medicament is prolonged, and the composition has great significance for the resistance treatment of the bakanae disease of the rice in China and the effective prevention and treatment of various rice seed-borne or soil-borne diseases.
(4) The quality is excellent, the cost is low, and the market prospect is wide: the prothioconazole is a novel broad-spectrum triazole thioketone bactericide, has a very wide bactericidal spectrum, has excellent prevention effect on all fungal diseases on grains, is important in triazole bactericides at present and has high cost performance; carboxin is a heterocyclic bactericide with a systemic effect, is a succinic dehydrogenase inhibitor, can permeate into germinated seeds to kill germs in the seeds, can promote the growth and development of plants, increase the photosynthesis efficiency, improve the adaptability of crops to drought, high temperature, diseases and insect pests and other stress factors, and has wide application and low price; the rice aphelenchoides can only prevent and not treat, and cartap still dominates in preventing and treating rice aphelenchoides at present. The three components are reasonably compounded, the new product is practically registered and developed, the problems existing in the prevention and treatment of rice seed-borne or soil-borne diseases can be effectively solved by the medicament, the root-promoting and seedling-strengthening effects are obvious, the cost is low, and the market prospect is wide.
Detailed Description
The present application is further illustrated below in conjunction with specific embodiments, it being understood that these embodiments are meant to be illustrative of the application and not limiting the scope of the application, and that modifications of the application, which are equivalent to those skilled in the art to which the application pertains, fall within the scope of the application defined in the appended claims after reading the application.
Bioassay example 1: indoor Activity assay.
Antibacterial activity of single and ternary compound agents of prothioconazole, carboxin and cartap on bakanae disease:
a) Test strain: rice bakanae germ (Fusariumfujikuroi) is collected from a paddy field in Jurong city of Jiangsu province, separated, identified and stored for later use by a plant protection research laboratory in Zhenjiang city agricultural science research institute in Jiangsu hilly area, and other rice bakanae germ strains can also be adopted. The strain was stored on Potato Sucrose Agar (PSA) slants (4 ℃).
B) Test agent: 95.2% (W/W) prothioconazole technical, shandong Hailier chemical Co., ltd; 98% (W/W) carboxin technical, xinyi Yongcheng chemical Co., ltd; 98% (W/W) cartap stock, lianghong Gangsu crop science and technology Co.
C) The test method comprises the following steps: referring to pesticide biological assay criterion NY/T1156.2-2006, the indoor toxicity of single test agent and ternary compound agents with different proportions on rice bakanae disease germs is determined by adopting a hypha growth rate method.
D) Data analysis: and calculating a regression equation, EC 50 and a 95% confidence limit of the single agent and the ternary compound agents with different proportions for inhibiting the growth of the hyphae of the bakanae disease germ of the rice by adopting a DPSv7.05 edition data processing system.
According to the Wadley method, the synergy coefficient (SR) is calculated. And evaluating the combined action type of the mixed medicament according to a synergistic coefficient (SR), namely, SR <0.5 is antagonism, SR is more than or equal to 0.5 and less than or equal to 1.5 is addition, SR >1.5 is synergistic effect .SR＝EC50(Eth)/EC50(Eob),EC50(Eth)＝(a+b+c)/[(a/EC50A)+(b/EC50B)+(c/EC50C)]., wherein A, B, C is a single medicament agent, a, b and c are the proportion of the corresponding single agents in the mixed medicament, EC 50 (Eth) is a theoretical value of the mixed medicament EC 50, and EC 50 (Eob) is an actual measurement value of the mixed medicament EC 50.
E) Results and analysis:
TABLE 1 biological Activity (toxicity) of Protexazole, carboxin and cartap and their formulations against bakanae disease germ of rice
In Table 1, the mass ratio of propiconazole, carboxin and cartap is shown.
Indoor measurement results show that EC 50 values of prothioconazole, carboxin and cartap for inhibiting growth of bakanae disease germ hyphae of rice are respectively 0.0259, 15.0514 and 1142.6225 mug/mL. Ternary combination of prothioconazole, carboxin and cartap, the mass ratio of the ternary combination is 1-15:1-10, and the synergistic coefficient of the compound agent for inhibiting bakanae disease bacteria of rice is 0.7660-2.4112, so that the ternary combination has addition or synergistic effect; when the mass ratio is between 1-5:1-10:1-5, the synergistic coefficient of the compound agent for inhibiting the bakanae disease bacteria of the rice is larger than 1.5, and the compound agent has a synergistic effect (table 1). The characteristics of prothioconazole, carboxin and cartap and the screening result of the indoor proportion are combined, and the optimal mass proportion of the ternary combination of prothioconazole, carboxin and cartap is preliminarily determined to be set between 1-5:1-10:1-5.
Preparation example 1: preparation of 24% prothioconazole, carboxin and cartap Wettable Powder (WP).
The wettable powder comprises the following components in percentage by mass: 2% prothioconazole, 2% carboxin, 20% cartap, 5% sodium lignin sulfonate (wetting agent), 3% dispersant NNO (dispersant), 0.5% isobutanol (penetrant), 2% sodium dodecylbenzene sulfonate (spreader), 0.8% sodium aluminosilicate (anti-caking agent), 0.5% calcium carbonate (stabilizer), 0.2% rose bengal (color warning agent) and kaolin (filler) make up 100%.
The preparation method comprises the following steps:
The preparation method comprises the steps of preparing materials according to the proportion and preparing 24% prothioconazole, carboxin and cartap by a conventional wettable powder processing preparation method.
Preparation example 2: preparation of 34% prothioconazole, carboxin and cartap.
The wettable powder comprises the following components in percentage by mass: 30% prothioconazole, 2% carboxin, 2% cartap, 4% sodium lignin sulfonate (wetting agent), 4% dispersant NNO (dispersant), 0.6% isobutanol (penetrant), 1.5% sodium dodecylbenzenesulfonate (spreader), 0.6% sodium aluminosilicate (anti-caking agent), 0.8% calcium carbonate (stabilizer), 0.1% rose bengal (color warning agent), and kaolin (filler) make up 100%.
The preparation method comprises the following steps:
the preparation method comprises the steps of preparing materials according to the proportion and preparing 34% prothioconazole, carboxin and cartap by a conventional wettable powder processing preparation method.
Preparation example 3:25.5% of prothioconazole, carboxin and cartap.
The wettable powder comprises the following components in percentage by mass: 1.5% prothioconazole, 22.5% carboxin, 1.5% cartap, 6% sodium lignin sulfonate (wetting agent), 2% dispersant NNO (dispersant), 0.8% isobutanol (penetrant), 1% sodium dodecylbenzenesulfonate (spreader), 1% sodium aluminosilicate (anti-caking agent), 0.4% calcium carbonate (stabilizer), 0.4% rose bengal (color warning agent), kaolin (filler) make up 100%.
The preparation method comprises the following steps:
The materials are prepared according to the proportion and prepared into 25.5 percent of prothioconazole, carboxin and cartap by a conventional wettable powder processing preparation method.
Preparation example 4: preparation of 23% prothioconazole, carboxin and cartap.
The wettable powder comprises the following components in percentage by mass: 5% prothioconazole, 10% carboxin, 8% cartap, 7% sodium lignin sulfonate (wetting agent), 3% dispersant NNO (dispersant), 1% isobutanol (penetrant), 1% sodium dodecylbenzene sulfonate (spreader), 0.8% sodium aluminosilicate (anti-caking agent), 0.6% calcium carbonate (stabilizer), 0.5% rose bengal (color warning agent) and kaolin (filler) make up 100%.
The preparation method comprises the following steps:
The 23% prothioconazole, carboxin and cartap are prepared by the conventional wettable powder processing preparation method.
Preparation example 5: preparation of 26% prothioconazole, carboxin and cartap seed treatment dispersible powder (ZF).
The seed treatment dispersible powder comprises the following components in percentage by mass: 4% prothioconazole, 16% carboxin, 6% cartap, 5% polyoxyethylene alkyl ether (wetting agent), 5% sodium alkylbenzenesulfonate (dispersing agent), 0.8% penetrant T (penetrant), 1.5% xanthan gum (film forming agent), 1% silicon dioxide (anti-caking agent), 0.8% polyvinyl alcohol (stabilizer), 0.5% carmine (color warning agent) and bentonite (filler) make up 100%.
The preparation method comprises the following steps:
the 26% prothioconazole, carboxin and cartap ZF are prepared by the preparation method of the above proportioning and conventional seed treatment dispersible powder.
Preparation example 6: preparation of 30% prothioconazole, carboxin and cartap ZF.
The seed treatment dispersible powder comprises the following components in percentage by mass: 10% of prothioconazole, 10% of carboxin, 10% of cartap, 4% of polyoxyethylene alkyl ether (wetting agent), 6% of sodium alkylbenzenesulfonate (dispersing agent), 1% of penetrating agent T (penetrating agent), 1% of xanthan gum (film forming agent), 0.6% of silicon dioxide (anti-caking agent), 0.6% of polyvinyl alcohol (stabilizing agent), 0.4% of carmine (color warning agent) and bentonite (filling agent) which make up 100%.
The preparation method comprises the following steps:
The preparation method comprises the steps of preparing materials according to the proportion and preparing 30% prothioconazole, carboxin and cartap ZF by processing dispersible powder by using seed treatment.
Preparation example 7:32% prothioconazole, carboxin and cartap ZF.
The seed treatment dispersible powder comprises the following components in percentage by mass: 4% prothioconazole, 18% carboxin, 10% cartap, 5% polyoxyethylene alkyl ether (wetting agent), 4% sodium alkylbenzenesulfonate (dispersing agent), 0.8% penetrant T (penetrant), 1.5% xanthan gum (film forming agent), 0.8% silicon dioxide (anti-caking agent), 0.5% polyvinyl alcohol (stabilizing agent), 0.8% carmine (color warning agent) and bentonite (filler) make up 100%.
The preparation method comprises the following steps:
The preparation method comprises the steps of preparing materials according to the proportion and preparing 32% prothioconazole, carboxin and cartap ZF by processing dispersible powder by using seed treatment.
Field efficacy example 1: the pesticide composition containing prothioconazole, carboxin and cartap has the field efficacy on bakanae disease and aphelenchoides disease of rice and root and seedling promotion and strengthening test.
The pesticide compositions of preparation examples 1 to 7 containing prothioconazole, carboxin and cartap were respectively prepared by taking 20% of prothioconazole and cartap (prepared by preparing the pro-drugs of prothioconazole and cartap according to the method of preparation example 1 in a ratio of 1:1) and 20% of carboxin and cartap (prepared by preparing the pro-drugs of carboxin and cartap according to the method of preparation example 1 in a ratio of 1:1) AS binary compound pesticide control medicaments, and taking 30% of prothioconazole OD (Anjiuyi agriculture Co., ltd.), 12% of carboxin AS (Shanxi He Di Yi agricultural Co., ltd.) and 6% of cartap AS (green shield plant protection pesticide experiment Co., ltd.) AS single-dose control medicaments, and carrying out field pesticide effects and root-strengthening tests of bakanae disease and Jiangpoint nematode disease.
The test treatment method comprises the following steps: the test site is located in a farm land of the agricultural science and technology innovation center of Zhenjiang agricultural science and research institute in Jiangsu hilly area of Jurong city white rabbits in Jiangsu province, the soil is loamy soil, the fertility is moderate, and the organic matter content is about 1.95%. The rice variety is salt japonica 456' (rice bakanae disease and rice seed with aphelenchoides besseyi). The test set 13 treatments, respectively: preparation examples 1-7, wherein the sum of the mass concentrations of prothioconazole and carboxin is 50 mug/mL (calculated by the sum of the mass concentrations of prothioconazole and carboxin serving AS main sterilization components is 50 mug/mL), and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap are respectively calculated by the sum of the mass concentrations of prothioconazole, carboxin, prothioconazole, carboxin and cartap serving AS main sterilization components is 50 mug/mL, and clear water blank control is adopted. 500g of salt japonica 456' rice seeds are soaked in the 1L of the above 13 treated liquid medicines or clear water for 48 hours, germinated for about 48 hours to half grain of bud length after soaking, and sowed in a seedbed of 5m multiplied by 1m, and each treatment is repeated for 3 times. At seedling age of 30 days, each treated seedling was individually transplanted to a 20m×2m field cell at a plant row spacing of about 15cm×20cm, and each treatment was randomly arranged. Fertilizer and water and other diseases and insect pests management in the rice growth period are conventional.
Before transplanting, 5-point sampling is carried out on each district, 20 seedlings are investigated for 100 seedlings in each district, the height of the seedlings, the total root number of each seedling, the length of main roots and the width of stem bases are respectively measured, then the seedlings are bagged, the seedlings are deactivated for 30min at 105 ℃, and the seedlings are dried to constant weight at 80 ℃ and then the dry mass of hundred seedlings is weighed. The plant disease rate of the bakanae and the plant disease rate of the aphelenchoides are respectively investigated in the heading and grouting period of the rice, the control effect is calculated, and the control effect variance analysis is carried out by adopting a DPSv7.05 edition data processing system and a Duncan new complex polar difference method. The disease rate and the prevention and treatment effect are calculated by the following formulas: disease rate = number of diseased plants/total number of investigation x 100%; control effect = [ (control disease rate-treatment disease rate)/control disease rate ] ×100%.
Test results show that the field control effect of 12 medicament treatments on the bakanae disease of the rice is as follows from high to low in sequence: preparation example 7, preparation example 5, preparation example 4, preparation example 6, preparation example 2, preparation example 1, preparation example 3, 20% prothioconazole fenitrothion WP, 30% prothioconazole OD, 20% carboxin fenitrothion WP, 12% carboxin WP and 6% cartap AS. The field control effects of the preparation examples 1-7 on the bakanae disease of the rice are higher than that of the binary proportioning medicament of 20% prothioconazole and cartap and 20% carboxin and cartap and the control medicament of 30% prothioconazole OD, 12% carboxin and 6% cartap AS, and the differences are obvious (Table 2). The effective dose of the cartap with the nematicide active ingredient is obviously higher, the control effect of the preparation example 1 on the rice stem tip nematode disease is higher than the control effect of all treatments such AS 20% of folpet, 20% of bronopol cartap, 6% of cartap AS and the like, and the difference is obvious; the effective dosages of the cartap prepared in the preparation example 4 are lower than 20% of the folpet WP, 20% of the bronopol WP and 6% of the cartap AS, but the control effect is quite similar and has no obvious difference; because the effective dose of cartap is obviously lower, the control effect of the preparation examples 2, 3, 5, 6 and 7 on the rice stem tip nematode disease is lower than that of 20 percent of folpet cartap, 20 percent of bronopol cartap and 6 percent of cartap AS, and the difference is obvious; 30% prothioconazole OD and 12% carboxin WP were essentially non-control of rice aphelenchoides disease (Table 2).
The pesticide composition containing prothioconazole, carboxin and cartap has good control effect on bakanae disease and spinetoram disease of rice, realizes the double effects of sterilization and disinsection of a medicament, and has obvious synergism compared with binary compounding of prothioconazole and cartap or binary compounding of carboxin and cartap and single dose after ternary compounding. Therefore, the pesticide composition provided by the invention has the advantages of drug reduction, synergism and broad-spectrum pest control, can delay the generation of drug resistance of diseases, and has great significance for the efficient prevention and control of seed-borne diseases such as bakanae disease, aphelenchoides besseyi and the like.
TABLE 2 field control effects of the inventive preparation on bakanae disease and aphelenchoides disease of rice
The preparation examples 1-7 were formulated with the mass concentration sum of prothioconazole and carboxin of 50. Mu.g/mL, 20% prothioconazole cartap, 20% carboxin cartap, 30% prothioconazole OD, 12% carboxin WP and 6% carboxin AS of 50. Mu.g/mL; the same column of data is marked with a different lower case letter indicating significant differences (P < 0.05), as follows.
The results of investigation on the quality of seedlings obtained in each treatment show that the seedling quality indexes of the preparation examples 1-7, such AS height, total root number, main root length, stem width, hundred-plant dry quality and the like, of the seedlings are higher than those of binary proportioning medicaments, namely 20% prothioconazole and cartap WP and 20% carboxin and cartap WP, and control medicaments, namely 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS, and the differences are remarkable (Table 3).
The pesticide composition containing prothioconazole, carboxin and cartap has the functions of promoting root and strengthening seedling, and the root and strengthening seedling after ternary compounding has obvious synergy compared with binary compounding of prothioconazole and cartap or carboxin and cartap and single dosage. The pesticide composition has the advantages of broad spectrum control, excellent control effect on seed-borne diseases such as bakanae disease, aphelenchoides disease and the like of rice, obvious synergy and root and seedling promotion effect.
Table 3 comparative seedling quality of the agent treated with the preparation of the example of the invention (salt japonica 456)
The preparation examples 1 to 7 were injected with the mass concentrations of prothioconazole and carboxin of 50. Mu.g/mL, and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS of 50. Mu.g/mL, respectively.
Field efficacy example 2: the optimized proportioning composition containing prothioconazole, carboxin and cartap has field efficacy on bakanae disease and aphelenchoides disease of rice and root-promoting and seedling-strengthening test.
The pesticide composition of the preparation examples 4-7, which contains prothioconazole, carboxin and cartap in a preferred proportion, was prepared by taking 20% of prothioconazole cartap (prepared by preparing the prothioconazole and cartap raw materials in a proportion of 1:1 according to the method of preparing wettable powder in example 1) and 20% of carboxin cartap WP (prepared by preparing the carboxin and cartap raw materials in a proportion of 1:1 according to the method of preparing wettable powder in example 1) as binary compound pesticide control medicaments, and taking 16% of prochloraz cartap (prochloraz: cartap=1:3) (Jiangsu green plant protection pesticide experiment limited company) and 20% of fenitropin cartap (fenitropin: fenitropin=1:1) (Jiangsu green plant protection pesticide experiment limited company) as control medicaments to develop field pesticide effects and root-promoting strong seedling tests of the bakanae disease and the spinetoram.
The test treatment method comprises the following steps: the test site is located in a farm land of the agricultural science and technology innovation center of Zhenjiang agricultural science and research institute in Jiangsu hilly area of Jurong city white rabbits in Jiangsu province, the soil is loamy soil, the fertility is moderate, and the organic matter content is about 1.85%. The rice variety is Wuyunjing 24' (rice bakanae disease and rice seed with aphelenchoides besseyi). The test set 13 treatments, respectively: 1500 and 3000 times liquid of preparation example 4, 2000 and 4000 times liquid of preparation example 5, 2000 and 4000 times liquid of preparation example 6, 2000 and 4000 times liquid of preparation example 7, 2000 times liquid of 20% prothioconazole cartap WP, 1000 times liquid of 20% carboxin cartap WP, 500 times liquid of 16% prochloraz cartap WP (recommended dose), 1000 times liquid of 20% fenitrothion cartap WP (recommended dose) and clear water blank. 500g of naturally occurring 'Wuyunjing 24' rice seeds are soaked in the above 13 treated 1L liquid medicine or clear water for 48h, germinated for about 48h to half grain length and sowed in a seedbed of 5m×1m, and each treatment is repeated for 3 times. At seedling age of 30 days, each treated seedling was individually transplanted to a 20m×2m field cell at a plant row spacing of about 15cm×20cm, and each treatment was randomly arranged. Fertilizer and water and other diseases and insect pests management in the rice growth period are conventional.
Before transplanting, 5-point sampling is carried out on each district, 20 seedlings are investigated for 100 seedlings in each district, the height of the seedlings, the total root number of each seedling, the length of main roots and the width of stem bases are respectively measured, then the seedlings are bagged, the seedlings are deactivated for 30min at 105 ℃, and the seedlings are dried to constant weight at 80 ℃ and then the dry mass of hundred seedlings is weighed. The plant disease rate of the bakanae and the plant disease rate of the aphelenchoides are respectively investigated in the heading and grouting period of the rice, the control effect is calculated, and the control effect variance analysis is carried out by adopting a DPSv7.05 edition data processing system and a Duncan new complex polar difference method. The disease rate and the prevention and treatment effect are calculated by the following formulas: disease rate = number of diseased plants/total number of investigation x 100%; control effect = [ (control disease rate-treatment disease rate)/control disease rate ] ×100%.
Test results show that the field control effect of 12 medicament treatments on the bakanae disease of the rice is as follows from high to low in sequence: preparation of example 7, 2000-fold solutions; preparation of example 5, 2000 times solution; preparation of example 4, 1500-fold solutions; preparation of example 6, 2000-fold solutions; preparation of example 7, 4000-fold solution; preparation of example 5, 4000 times liquid; preparation of example 4, 3000 times liquid; preparation of example 6, 4000 times liquid; 20% prothioconazole and cartap WP 2000-fold liquid; 20% of cyanogen mycoester and cartap WP 1000 times liquid; 20% carboxin and cartap WP 1000 times liquid; and 16% prochloraz and cartap WP 500 times liquid. 2000 and 4000 times the solutions of example 7 were prepared; 2000 and 4000 times the solutions of example 5 were prepared; the field control effects of 1500-time liquid and 3000-time liquid of preparation example 4 and 2000-time liquid and 4000-time liquid of preparation example 6 on bakanae disease of rice are higher than that of the binary compound agent of 20% prothioconazole and cartap WP 2000-time liquid and 20% carboxin and cartap WP 1000-time liquid, and the control agent of 20% fenitrothion and cartap WP 1000-time liquid and 16% prochloraz and cartap WP 500-time liquid, and the differences are obvious. Because the effective dose of cartap is relatively high, the control effect of 16% prochloraz and cartap SC 500 times liquid on the aphalocrocis medinalis disease reaches 100%; the control effect of 20% carboxin and cartap WP 1000 times liquid and 20% fenitrothion and cartap WP 1000 times liquid on dry tip nematode disease reaches 98.76% and 99.07% respectively. 2000 and 4000 times the solutions of example 7 were prepared; 2000 and 4000 times the solutions of example 5 were prepared; the control effect of 1500 and 3000 times of the preparation example 4 and 2000 and 4000 times of the preparation example 6 on the rice dry-tip nematode disease is higher than that of the binary compound agent 20% prothioconazole and cartap WP 2000 times, and the difference is obvious (table 4).
The pesticide composition containing the prothioconazole, the carboxin and the cartap has better control effect on bakanae disease and aphalocrocis medinalis of rice, when the pesticide composition is applied at a proper dosage, the control effect is obviously better than that of a binary compound agent of 20% of prothioconazole, cartap and 20% of carboxin, cartap and 1000 times of liquid, and the control effect is obviously better than that of the conventional pesticide of 20% of fenitrothion, cartap and 16% of prochloraz, cartap and the like applied at a recommended dosage when the pesticide composition is applied at a certain safety dosage, the pesticide composition has the advantages of reduced pesticide effect, low cost, environmental friendliness, safety and obvious economic, ecological and social benefits.
TABLE 4 field control of bakanae disease and Aphelenchoides besseyi in rice prepared by the preferred compositions of the examples of the invention
The seedling quality investigation results of each treatment show that 2000 and 4000 times of the liquid in preparation example 7, 2000 and 4000 times of the liquid in preparation example 5, 1500 and 2000 times of the liquid in preparation example 4, 2000 and 4000 times of the liquid in preparation example 6, seedling quality indexes such as seedling height, total root number, main root length, stem width and hundred-plant dry quality of each plant are higher than those of binary proportioning medicament 20% prothioconazole and cartap and 20% carboxin and cartap WP, and contrast medicament 20% fenitrothion and cartap 1000 times of liquid and 16% prochloraz and cartap WP 500 times of liquid, and the difference is remarkable (table 5).
The pesticide composition containing prothioconazole, carboxin and cartap has root and seedling promoting effect, and the root and seedling promoting effect after ternary combination is obvious in synergy compared with binary combination of prothioconazole and cartap or carboxin and cartap and the conventional medicament of 20% of cyhalothrin-cartap WP and 16% of prochloraz-cartap WP. The pesticide composition has excellent control effect on seed-borne diseases such as bakanae disease, aphelenchoides disease and the like of rice, obvious synergy and obvious root and seedling promotion effect.
Table 5 preferred compositions prepared in accordance with the examples of the invention treat seedling quality comparison (Wuyun japonica 24)
Field efficacy example 3: the pesticide composition containing prothioconazole, carboxin and cartap has the effect on the field of rice seedling diseases and is used for root-promoting and seedling-strengthening test.
Design of test agents: the same as in field efficacy example 1.
The test treatment method comprises the following steps: the test site is located in a farm land of the agricultural science and technology innovation center of Zhenjiang agricultural science and research institute in Jiangsu hilly area of Jurong city white rabbits in Jiangsu province, the soil is loam, the fertility is moderate, and the organic matter content is about 1.80%. The rice variety is 'nan japonica 5718'. The experiment was performed in 13 treatments, as in field efficacy example 1. 500g of rice seeds of 'nan japonica 5718' are soaked in the above-mentioned 13 treated 1L of the liquid medicine or clear water for 48h, germinated for about 48h to half grain of bud length after soaking, and sowed in a seedbed of 5m×1m, and each treatment is repeated 3 times. At seedling age of 30 days, each treated seedling was individually transplanted to a 20m×2m field cell at a plant row spacing of about 15cm×20cm, and each treatment was randomly arranged. Fertilizer and water and other diseases and insect pests management in the rice growth period are conventional.
When obvious seedling rot disease symptoms appear in the clear water control area in the seedling stage of the rice, sampling five points on the diagonal line of each area, surveying 0.1 square meter for each point, recording and surveying total plant number and seedling rot disease plant number, calculating the control effect, and performing control effect variance analysis by adopting a DPSv7.05 edition data processing system and a Duncan new complex polar difference method. The disease rate and the prevention and treatment effect are calculated by the following formulas: disease rate = number of diseased plants/total number of investigation x 100%; control effect = [ (control disease rate-treatment disease rate)/control disease rate ] ×100%. Before transplanting, 5-point sampling is carried out on each district, 20 seedlings are investigated for 100 seedlings in each district, the height of the seedlings, the total root number of each seedling, the length of main roots and the width of stem bases are respectively measured, then the seedlings are bagged, the seedlings are deactivated for 30min at 105 ℃, and the seedlings are dried to constant weight at 80 ℃ and then the dry mass of hundred seedlings is weighed.
The test results show that the field prevention effect of 12 chemical treatments on the rice seedling diseases is as follows from high to low in sequence: preparation example 7, preparation example 5, preparation example 4, preparation example 6, preparation example 2, preparation example 1, preparation example 3, 20% prothioconazole fenitrothion WP, 30% prothioconazole OD, 20% carboxin fenitrothion WP, 12% carboxin WP and 6% cartap AS. The field control effects of the preparation examples 1-7 on rice seedling diseases are higher than those of the binary proportioning medicament 20% prothioconazole cartap, 20% carboxin cartap and the control medicament 30% prothioconazole OD, 12% carboxin WP and 6% cartap, and the differences are obvious (Table 6).
The pesticide composition containing prothioconazole, carboxin and cartap has excellent prevention effect on rice seedling diseases, and the field prevention effect after ternary compounding is obvious in synergy compared with binary compounding of prothioconazole and cartap or carboxin and cartap and single dosage. Therefore, the pesticide composition provided by the invention has the advantages of drug reduction and synergism, and has great significance for efficiently preventing and controlling the rice seedling rot.
TABLE 6 field control effect of the preparation prepared in the example of the invention on rice seedling disease (Nanjing 5718)
The preparation examples 1 to 7 were injected with the mass concentrations of prothioconazole and carboxin of 50. Mu.g/mL, and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS of 50. Mu.g/mL, respectively.
The seedling quality survey results of the treatment of each medicament show that the seedling quality indexes of the preparation examples 1-7, such AS seedling height, total root number, main root length, stem base width, hundred plant stem quality and the like, are higher than the binary proportioning medicaments of 20% prothioconazole cartap, 20% carboxin cartap, and control medicaments of 30% prothioconazole OD, 12% carboxin WP and 6% cartap, and the difference is remarkable (Table 7).
The pesticide composition containing prothioconazole, carboxin and cartap has the functions of promoting root and strengthening seedling, and the root and strengthening seedling after ternary compounding has obvious synergy compared with binary compounding of prothioconazole and cartap or carboxin and cartap and single dosage. The pesticide composition has excellent prevention effect on rice seedling diseases and obvious synergy, and has the functions of promoting root and strengthening seedlings.
Table 7 comparative seedling quality of the agent treated with the preparation of the example of the invention (Nanjing 5718)
The preparation examples 1 to 7 were injected with the mass concentrations of prothioconazole and carboxin of 50. Mu.g/mL, and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS of 50. Mu.g/mL, respectively.
Field efficacy example 4: the pesticide composition containing prothioconazole, carboxin and cartap has the effects on the rice damping-off in the field and is used for root and seedling promotion test.
Design of test agents: the same as in field efficacy example 1.
The test treatment method comprises the following steps: the test site is located in a farm land of the Zhenjiang agricultural science and technology innovation center in the Jiangsu hilly area of the white rabbits town in Jurong City of Jiangsu province, the soil is loamy soil, the fertility is moderate, and the organic matter content is about 1.96%. The rice variety is Hu Soft 1212'. The experiment was performed in 13 treatments, as in field efficacy example 1. 500g of Hu Soft 1212' rice seeds were immersed in the above 13 treated 1L of the above-mentioned liquid or clear water for 48 hours, germinated for about 48 hours to half grain length, and sown in 5 m.times.1m seedbeds, and each treatment was repeated 3 times. At seedling age of 30 days, each treated seedling was individually transplanted to a 20m×2m field cell at a plant row spacing of about 15cm×20cm, and each treatment was randomly arranged. Fertilizer and water and other diseases and insect pests management in the rice growth period are conventional.
Before transplanting, 5-point sampling is carried out on each district, 20 seedlings are investigated for 100 seedlings in each district, the height of the seedlings, the total root number of each seedling, the length of main roots and the width of stem bases are respectively measured, then the seedlings are bagged, the seedlings are deactivated for 30min at 105 ℃, and the seedlings are dried to constant weight at 80 ℃ and then the dry mass of hundred seedlings is weighed. Before transplanting rice, sampling five diagonal points in each district, investigating 0.1 square meter each point, recording and investigating total plant number and damping-off disease plant number, calculating control efficiency, and performing control efficiency variance analysis by adopting a DPSv7.05 edition data processing system and a Duncan new complex polar difference method. The disease rate and the prevention and treatment effect are calculated by the following formulas: disease rate = number of diseased plants/total number of investigation x 100%; control effect = [ (control disease rate-treatment disease rate)/control disease rate ] ×100%.
Test results show that the field control effect of the 12 chemical treatments on the rice damping-off is as follows from high to low in sequence: preparation example 7, preparation example 5, preparation example 4, preparation example 6, preparation example 2, preparation example 1, preparation example 3, 20% prothioconazole fenitrothion WP, 30% prothioconazole OD, 20% carboxin fenitrothion WP, 12% carboxin WP and 6% cartap AS. The field control effects of the preparation examples 1-7 on the rice damping-off are higher than those of the binary proportioning medicament 20% prothioconazole and cartap and 220% carboxin and cartap and the control medicament 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS, and the differences are obvious (Table 8).
The pesticide composition containing prothioconazole, carboxin and cartap has good control effect on rice damping-off, and the field control effect after ternary compounding is obvious in synergy compared with binary compounding of prothioconazole and cartap or carboxin and cartap and single dosage. Therefore, the pesticide composition disclosed by the invention has a wide control spectrum, reduces the pesticide and increases the efficiency, and has great application value for effectively controlling the rice damping-off.
Table 8 the preparation prepared in the example of the invention has the effect of preventing and curing rice damping-off in the field (Hu Soft 1212)
The preparation examples 1 to 7 were injected with the mass concentrations of prothioconazole and carboxin of 50. Mu.g/mL, and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS of 50. Mu.g/mL, respectively.
The seedling quality survey results of the treatment of each medicament show that the seedling quality indexes of the preparation examples 1-7, such AS seedling height, total root number, main root length, stem base width, hundred plant stem quality and the like, are higher than the binary proportioning medicaments of 20% prothioconazole cartap, 20% carboxin cartap, and control medicaments of 30% prothioconazole OD, 12% carboxin WP and 6% cartap, and the difference is remarkable (Table 9).
The pesticide composition containing prothioconazole, carboxin and cartap has the effects of promoting root and strengthening seedling, and the effects of promoting root and strengthening seedling after ternary compounding are obvious in synergy compared with binary compounding of prothioconazole and cartap or carboxin and cartap and single dosage. Therefore, the pesticide composition provided by the invention has excellent control effect and obvious synergy on rice damping-off, has root and seedling promotion effects, and has important significance on ensuring high and stable rice yield.
Table 9 comparative seedling quality of the agent treated with the inventive example (Hu Soft 1212)
The preparation examples 1 to 7 were injected with the mass concentrations of prothioconazole and carboxin of 50. Mu.g/mL, and the mass concentrations of 20% prothioconazole and cartap, 20% carboxin and cartap, 30% prothioconazole OD, 12% carboxin WP and 6% cartap AS of 50. Mu.g/mL, respectively.
According to the invention, the mass ratios of the prothioconazole, the carboxin and the cartap in preparation examples 4, 5, 6 and 7 are respectively 1:2:1.6, 1:4:1.5, 1:1:1, 1:4.5:2.5, which are all the preferred ratios and are verified in the field, and the mass ratio of the prothioconazole, the carboxin and the cartap is 1:1-4.5:1-2.5.
Claims (10)
1. A pesticide composition containing prothioconazole, carboxin and cartap is characterized in that the active ingredients are prothioconazole, carboxin and cartap; the mass ratio of the prothioconazole to the carboxin to the cartap is 1-15:1-10.
2. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 1, wherein said pesticide composition is characterized in that: the mass ratio of the prothioconazole to the carboxin to the cartap is 1-5:1-10:1-5.
3. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 2, wherein said pesticide composition is characterized in that: the mass ratio of the prothioconazole to the carboxin to the cartap is 1:1-4.5:1-2.5.
4. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 1, further comprising an auxiliary agent.
5. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 1 or 4, wherein said pesticide composition is characterized in that: the mass percentage of the active ingredients in the pesticide composition is 10-50%.
6. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 5, wherein said pesticide composition is characterized in that: the dosage form is wettable powder or seed treatment dispersible powder.
7. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 6, wherein said pesticide composition is characterized in that: for wettable powder, the auxiliary agent is selected from one or more of filler, wetting agent, dispersing agent, penetrating agent, spreading agent, anti-caking agent, stabilizer and warning color; for the seed treatment dispersible powder, the auxiliary agent is selected from one or more of a filler, a wetting agent, a dispersing agent, a penetrating agent, a film forming agent, an anti-caking agent, a stabilizing agent and a color warning agent; for wettable powder, the filler is selected from kaolin, the wetting agent is selected from sodium lignin sulfonate, the dispersing agent is selected from dispersing agent NNO, the penetrating agent is selected from isobutanol, the spreading agent is selected from sodium dodecyl benzene sulfonate, the anti-caking agent is selected from sodium aluminosilicate, the stabilizing agent is selected from calcium carbonate, and the warning color is selected from rose bengal; for seed treatment dispersible powders, the filler is selected from bentonite, the wetting agent is selected from polyoxyethylene alkyl ether, the dispersing agent is selected from sodium alkylbenzenesulfonate, the penetrating agent is selected from penetrating agent T, the film forming agent is selected from xanthan gum, the anti-caking agent is selected from silicon dioxide, the stabilizing agent is selected from polyvinyl alcohol, and the color warning agent is selected from carmine.
8. The pesticide composition containing prothioconazole, carboxin and cartap according to claim 7, wherein said pesticide composition is characterized in that: the wettable powder comprises the following components in percentage by mass: 1.5 to 30 percent of prothioconazole, 2 to 22.5 percent of carboxin, 1.5 to 20 percent of cartap, 4 to 7 percent of wetting agent, 2 to 4 percent of dispersing agent, 0.5 to 1 percent of penetrating agent, 1 to 2 percent of spreading agent, 0.6 to 1 percent of anti-caking agent, 0.4 to 0.8 percent of stabilizing agent, 0.1 to 0.5 percent of color warning agent and 100 percent of filler complement;
The seed treatment dispersible powder comprises the following components in percentage by mass: 4 to 10 percent of prothioconazole, 10 to 18 percent of carboxin, 6 to 10 percent of cartap, 4 to 5 percent of wetting agent, 4 to 6 percent of dispersing agent, 0.8 to 1 percent of penetrating agent, 1 to 1.5 percent of film forming agent, 0.6 to 1 percent of anti-caking agent, 0.5 to 0.8 percent of stabilizing agent, 0.4 to 0.8 percent of color warning agent and 100 percent of filler.
9. The use of a pesticide composition containing prothioconazole, carboxin and cartap according to any one of claims 1-8 in controlling bakanae disease or/and rice seedling rot or/and rice seedling blight or/and rice aphelenchoides.
10. The use of a pesticide composition containing prothioconazole, carboxin and cartap according to any one of claims 1-8 in root-promoting and seedling-strengthening of rice.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410523693.6A CN118415179A (en) | 2024-04-28 | 2024-04-28 | Pesticide composition containing prothioconazole, carboxin and cartap and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202410523693.6A CN118415179A (en) | 2024-04-28 | 2024-04-28 | Pesticide composition containing prothioconazole, carboxin and cartap and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN118415179A true CN118415179A (en) | 2024-08-02 |
Family
ID=92325964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202410523693.6A Pending CN118415179A (en) | 2024-04-28 | 2024-04-28 | Pesticide composition containing prothioconazole, carboxin and cartap and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN118415179A (en) |
-
2024
- 2024-04-28 CN CN202410523693.6A patent/CN118415179A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Liu et al. | An integrated prevention strategy to address problems associated with continuous cropping of watermelon caused by Fusarium oxysporum | |
| CN111758736B (en) | Rice seed treating agent containing prothioconazole, imazalil and cartap and application thereof | |
| Wang et al. | Improved control of clubroot (Plasmodiophora brassicae) by a mixture of a fungicide and a plant defense inducer | |
| Michel | Ten years of biofumigation research in Switzerland | |
| CN112674108A (en) | Compound seed coating agent | |
| CN112602718A (en) | Nematicidal agricultural composition containing pyraoxystrobin and cyclobutrifuram | |
| CN101946777A (en) | Method for preventing and treating mikania micrantha by mixing fluroxypyr and ametryn | |
| CN108849985B (en) | Ternary compound biological agent and application thereof in prevention and treatment of ginger bacterial wilt | |
| CN103875712A (en) | Safe pleietrepie rice seed treating agent | |
| Tang et al. | Field evaluation of Sclerotium rolfsii, a biological control agent for broadleaf weeds in dry, direct-seeded rice | |
| CN118415179A (en) | Pesticide composition containing prothioconazole, carboxin and cartap and application thereof | |
| CN107279161A (en) | A kind of bactericidal composition containing folpet and fluopyram | |
| Saloua et al. | In Vitro and in Vivo Evaluating the Efficacy of Salicylic Acid and Gibberellic Acid Against Fusariumverticillioides in Garlic (Allium Sativuml) | |
| CN101133737A (en) | 20butylthio .tebuconazole water dispersible powder and method of manufacturing the same | |
| Soesanto et al. | Potency of two Trichoderma harzianum isolates in liquid and solid organic formula for controlling bacterial wilt on tomato in the field | |
| Rizwan et al. | Efficacy of botanical insecticides against linseed budfly (Dasyneura lini, barnes) in linseed (Linum usitatissimum linn.) | |
| CN113826635B (en) | Synergistic bactericide and application thereof | |
| EL-MORSI et al. | Efficacy of some organic compounds against root rot wilt diseases of olive transplants and their growth response in New Valley governorate, Egypt | |
| Chuaboon et al. | New application strategies of wood vinegar for managing rice disease under farming production | |
| CN116267945B (en) | Pesticide composition for preventing and treating gummy stem blight of melons | |
| Mansfield et al. | Novel bacterial seed treatment protects wheat seedlings from insect damage | |
| CN117678601B (en) | Application of benidiammonium in preventing and controlling plant bacterial diseases | |
| CN114982770B (en) | Composition for preventing and treating sesame wilt and application thereof | |
| CN116195591B (en) | Bactericide composition for preventing and treating gummy stem blight of melons | |
| CN116391721A (en) | Pesticide composition containing triticonazole, bronopol and cartap and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |