CN118304168A

CN118304168A - Liquid preparation system

Info

Publication number: CN118304168A
Application number: CN202310467636.6A
Authority: CN
Inventors: 林道斌; 廖文; 李学良
Original assignee: Meilan Hangzhou Pharmaceutical Technology Co ltd
Current assignee: Meilan Hangzhou Pharmaceutical Technology Co ltd
Priority date: 2023-01-06
Filing date: 2023-04-24
Publication date: 2024-07-09
Also published as: CN118304173A; CN118304169A; CN118304171A; CN118304167A; CN118304811A; CN219814590U; CN118304170A; CN118304172A; CN219814711U

Abstract

The present disclosure describes a liquid dispensing system comprising a liquid dispensing device and a dosing platform, the liquid dispensing device comprising a drug vial handling device, a liquid bag handling device, and a suction injector handling device, the drug vial handling device, the liquid bag handling device, and the suction injector handling device cooperating to transfer liquid between a drug vial and a liquid bag through a suction injector, the drug vial handling device comprising a drug vial loading mechanism for loading a drug vial, the drug vial loading mechanism comprising a frame, and a drug cartridge having a drug vial compartment for receiving the drug vial and removably assembled to the frame; the medicine adding platform is used for providing an environment for loading medicine bottles for the medicine boxes, medicine box information is recorded on the medicine boxes, before medicine bottles are loaded on the medicine boxes, medicine bottle information of the medicine boxes preloaded with the medicine bottles is compared with the medicine box information, and after the operation of loading the medicine bottles on the medicine boxes is completed, the medicine boxes loaded with the medicine bottles are assembled on the frame body. Thus, an automatic liquid dispensing system is provided which can improve the dosing accuracy of the liquid dispensing system.

Description

Liquid preparation system

Technical Field

The present disclosure relates generally to the technical field of medical devices, and in particular to a fluid dispensing system.

Background

Infusion is a medical method commonly used in clinic, by which liquid substances such as medical fluids, nutritional fluids, etc. can be infused into a patient to assist in patient recovery. When a patient needs to receive transfusion, etc., a plurality of different transfusion medicines are often required to be mixed according to the state of illness so as to prepare therapeutic liquid medicine with better curative effect. In practical applications, when a large amount of infusion is required, because it is difficult to perform efficient liquid medicine preparation in a manual operation manner, an automatic liquid preparation system is generally adopted to assist medical staff in preparing liquid.

Currently, in automated dispensing systems, vials are typically stored in a dedicated magazine or bin, and the take out device or manipulator takes the desired vial from the magazine or bin in which it is stored when needed. When there are fewer vials in the magazine or reservoir, the healthcare worker is often required to dose the magazine or reservoir in advance.

However, when a medical staff is dosing a medicine cartridge, the medical staff often uses the characters on the medicine bottle or the medicine box loaded with the medicine bottle to identify the type and medicine information of the medicine bottle. However, in the process of dosing large batches, the complete manual comparison may be error-prone, which may lead to incorrect vials (or medicines) being loaded into the cartridge, resulting in errors in the subsequent dosing.

Disclosure of Invention

The present disclosure has been made in view of the above-described circumstances, and an object thereof is to provide an automated liquid dispensing system capable of improving the accuracy of the dosing of the liquid dispensing system.

To this end, the present disclosure provides a liquid dispensing system including a liquid dispensing device including a medicine bottle handling device, a liquid bag handling device, and a suction injector handling device that cooperate to transfer liquid between a medicine bottle and a liquid bag by a suction injector, the medicine bottle handling device including a medicine bottle loading mechanism for loading the medicine bottle and a medicine bottle handling mechanism for handling the medicine bottle, the medicine bottle loading mechanism including a frame body, and a medicine cartridge having a medicine bottle bin for accommodating the medicine bottle and detachably assembled to the frame body; the medicine loading platform is used for providing an environment for loading the medicine bottles for the medicine boxes, medicine box information is recorded on the medicine boxes, before the medicine boxes are loaded with the medicine bottles, medicine bottle information of the medicine bottles preloaded is compared with the medicine box information, and after the operation of loading the medicine bottles into the medicine boxes is completed, the medicine boxes loaded with the medicine bottles are assembled on the frame body.

In the present disclosure, the automatic pipetting of the pipettor between the medicine bottle and the liquid bag can be achieved by the cooperation of the medicine bottle processing device, the liquid bag processing device, and the pipettor processing device. In addition, before medicine bottles are loaded into the medicine boxes, the medicine bottle information of the preloaded medicine bottles is compared with the medicine box information, so that a comparison result of whether the preloaded medicine bottles are matched with the current medicine boxes or not can be obtained, an operator can be guided to load the medicine bottles into the medicine boxes according to the comparison result, and the medicine adding accuracy of the liquid distribution system can be improved.

In addition, in the liquid dispensing system related to the present disclosure, optionally, the liquid dispensing device further includes a cabinet body having an accommodation space, and an air flow guiding mechanism, the cabinet body includes a porous plate horizontally disposed, the porous plate divides the accommodation space of the cabinet body into an upper half and a lower half, the medicine bottle processing device, the liquid bag processing device and the suction injector processing device are located in the upper half of the accommodation space, the air flow guiding mechanism includes an air inlet structure including a first filter layer and an air supply part, the air inlet structure is located at the top of the cabinet body and is communicated with the upper half of the accommodation space, the air outlet structure has a second filter layer and an air exhaust part, and the air outlet structure is communicated with the lower half of the accommodation space. In this case, through the air inlet structure and the air outlet structure, an air flow circulation loop can be formed in the accommodating space of the cabinet body, so that air in the accommodating space flows, clean air flow can be input into the accommodating space, and air in the accommodating space can be discharged, and the cleanliness of the accommodating space of the cabinet body can be improved. In addition, since the position where the air inlet structure is provided is higher than the position where the air outlet structure is provided, when the accommodating space of the cabinet body sprays the disinfectant such as sterilizing alcohol, the efficiency of discharging the residual disinfectant remaining in the air out of the accommodating space of the cabinet body can be improved by the air flow flowing from top to bottom.

In addition, in the liquid dispensing system related to the present disclosure, optionally, the liquid dispensing system further includes a monitoring device, where the monitoring device includes a first monitoring mechanism for monitoring a liquid dispensing process and disposed in the liquid dispensing device, and a second monitoring mechanism for monitoring a loading process of the medicine bottle and disposed in the dosing platform. Under the condition, the first monitoring mechanism is used for monitoring the liquid preparation process, and the whole process of the liquid preparation process can be recorded, so that the liquid preparation process can be traced back and source can be conveniently tracked; the second monitoring mechanism is used for monitoring the medicine bottle loading process, and recording the whole process of the medicine adding process, so that the medicine adding process can be traced back and tracked.

In addition, in the liquid dispensing system related to the disclosure, optionally, the medicine adding platform includes an operation platform with a reader-writer, a scanner, and a control center with a display screen and in communication connection with the reader-writer and the scanner, the medicine box is provided with an electronic tag with medicine box information recorded thereon, when the medicine box is placed on the operation platform, the reader-writer reads the electronic tag to obtain the medicine box information and transmits the medicine box information to the control center, and before loading the medicine box with the medicine box, the scanner scans a bar code of the medicine box information recorded with the preloaded medicine box to obtain the medicine box information and transmits the medicine box information to the control center, and the control center compares the medicine box information with the medicine box information and displays a comparison result on the display screen. In this case, when the cartridge is placed on the operation platform, the reader/writer reads the electronic tag on the cartridge to acquire the cartridge information and transmits the cartridge information to the control center, so that the control center can acquire first information such as the serial number and the adapted vial type for the cartridge; when loading a vial into a cartridge, a scanner scans the barcode of the vial and can acquire vial information and transmit the vial information to a control center so that the control center can acquire second information for the vial, such as the vial type and the loaded drug. On the one hand, the control center can obtain whether the preloaded medicine bottle is matched with the comparison result of the current medicine box or not by comparing the first information with the second information, and the comparison result is displayed on the display screen; on the other hand, the control center can acquire the association result of which medicine is loaded in the current medicine box by associating the first information with the second information, and the association result is displayed on a display screen; therefore, operators can be guided to load medicine bottles into the medicine boxes according to the comparison result, and whether the medicine loaded in the current medicine boxes is correct or not is confirmed according to the association result, so that the medicine adding accuracy of the liquid distribution system can be improved. In addition, the control center acquires the second information, so that the information of the medicines added to the liquid distribution system can be recorded conveniently, and the retrospective source-following of the medicine adding process is facilitated.

In the liquid dispensing system according to the present disclosure, the liquid bag processing apparatus may further include a liquid bag loading mechanism for loading a liquid bag, and a movable liquid bag carrying mechanism for carrying the liquid bag; the suction and injection device processing device comprises a suction and injection device carrying mechanism for carrying the suction and injection device, a movable suction and injection device carrying mechanism for carrying the suction and injection device, and a liquid transferring mechanism arranged on the suction and injection device carrying mechanism; the liquid dispensing device is provided with a first liquid transferring station and a second liquid transferring station, the first liquid transferring station is a region where the moving track of the medicine bottle carrying mechanism and the moving track of the liquid sucking and injecting device carrying mechanism can be overlapped, the second liquid transferring station is a region where the moving track of the medicine bag carrying mechanism and the moving track of the liquid sucking and injecting device carrying mechanism can be overlapped, when liquid is dispensed, the medicine bottle carrying mechanism moves the medicine bottle to the first liquid transferring station, the liquid bag carrying mechanism moves the liquid bag to the second liquid transferring station, the liquid sucking and injecting device carrying mechanism moves the liquid sucking and injecting device between the first liquid transferring station and the second liquid transferring station, and the liquid sucking and injecting device is controlled to move liquid between the medicine bottle and the liquid bag through the liquid transferring mechanism. In this case, at the first pipetting station, the pipetting mechanism is enabled to control the pipettor to aspirate or infuse a drug from or into the drug vial by cooperation between the drug vial handling mechanism and the pipettor handling mechanism; at the second pipetting station, the pipetting mechanism can control the pipetting device to inject medicine into the liquid bag or suck solution from the liquid bag through the cooperation between the liquid bag conveying mechanism and the pipetting device conveying mechanism. Thereby, the automatic pipetting device can automatically pipetting between the medicine bottle and the liquid bag.

In addition, in the liquid dispensing system according to the present disclosure, optionally, the medicine bottle loading mechanism includes a blocking portion provided at one end of the medicine box and openable at a mouth of the medicine bottle bin, and a pushing portion provided movably to the medicine box and capable of applying a pushing action to a medicine bottle in the medicine bottle bin in a direction from a rear of the medicine bottle bin to the mouth of the medicine bottle bin, the medicine bottle handling mechanism has a medicine bottle holding portion that releasably holds the medicine bottle, a movable first base, and a touch portion that cooperates with the blocking portion to open the mouth of the medicine bottle bin, the medicine bottle holding portion is provided to the first base, the touch portion includes a mounting member, and a touch member and a detection member that are provided on the mounting member, the touch member is movably provided to the mounting member and has a preset detection area corresponding to a position of the blocking portion when the blocking portion is opened, the touch member has at least a detection area when the blocking portion is applied to the blocking portion, and the touch member has a detection area when the detection member is opened. In this case, when the medicine bottle carrying mechanism picks up the medicine bottle, the mouth of the medicine bottle bin can be opened by the cooperation between the touch part and the blocking part, so that the medicine bottle can be taken out conveniently; in addition, after the medicine bottle carrying mechanism finishes picking up the medicine bottle, the detection member detects the position of the touch member, so that the state information of the blocking part can be fed back, and whether the detection blocking part can be normally closed or not can be confirmed conveniently. Thereby, the medicine bottle conveying mechanism can automatically pick up the medicine bottle from the medicine bottle carrying mechanism.

In addition, in the liquid dispensing system according to the present disclosure, optionally, the liquid bag transporting mechanism includes a movable base, a support base rotatably disposed on the base about a rotation axis, a liquid bag holding portion, and a suction cup, the liquid bag holding portion is disposed on the support base, and when dispensing liquid, the liquid bag transporting mechanism holds the liquid bag and moves to the second liquid transfer station, and makes the liquid bag form a predetermined angle with the rotation axis, and the suction cup adsorbs the liquid bag at the predetermined angle with the rotation axis. In this case, the liquid bag and the rotation shaft can be made to have a predetermined angle by rotating the support base, so that the suction and injection device cooperates with the liquid bag at the same predetermined angle to transfer the liquid medicine, thereby simulating the manual pipetting operation to the maximum extent. In addition, the stability of the liquid bag during rotation can be improved by adsorbing the liquid bag through the sucker, so that the liquid bag and the suction injector can be matched for pipetting conveniently.

In addition, in the liquid dispensing system according to the present disclosure, optionally, the syringe handling device further includes a calibration mechanism having a calibration area and configured to calibrate a position of the syringe, and when dispensing liquid, the syringe handling mechanism moves the syringe to the calibration area, the calibration mechanism calibrates a position of a syringe of the syringe to obtain a calibration coordinate value of the syringe, and the syringe handling mechanism plans a movement route based on the calibration coordinate value so that the syringe moves between the first pipetting station and the second pipetting station. In this case, the position of the needle tube can be calibrated by the calibration mechanism, and the inhaler can be accurately moved to a predetermined position to perform the inhalation of the medicine in cooperation with the container such as the vial and the liquid bag.

In addition, in the liquid dispensing system according to the present disclosure, optionally, the medicine bottle is an ampoule bottle and includes a main body portion, a cap, and a bottleneck connecting the main body portion and the cap, the medicine bottle handling apparatus includes an ampoule bottle cap removing mechanism including a scribing mechanism for scribing the bottleneck and a bottle knocking mechanism including a rotating portion having a cutter wheel, the bottle knocking mechanism has a first base and a thin rod rotatably provided to the first base, the ampoule bottle cap removing mechanism has a bottle cutting station and a bottle knocking station, the medicine bottle handling mechanism carries the medicine bottle to the bottle cutting station, the cutter wheel rotates and cuts the bottleneck, the medicine bottle handling mechanism carries the cut medicine bottle to the bottle knocking station, the thin rod rotates and the cap is knocked to separate the bottle cap from the bottleneck. Under the condition, firstly, the ampoule bottle is moved to the bottle cutting station to cut the bottle neck of the ampoule bottle by using the cutting mechanism, then, the cut ampoule bottle is moved to the bottle knocking station, and the bottle cap is knocked by using the bottle knocking mechanism so as to separate the bottle cap from the bottle neck, so that the bottle cap of the ampoule bottle can be separated from the bottle neck in a full-automatic mode, and the bottle cap removing efficiency of the ampoule bottle can be improved.

In addition, in the liquid dispensing system according to the present disclosure, optionally, the medicine bottle is a penicillin bottle and includes a bottle body having a receiving chamber, a bottle neck having a hollow passage communicating with the receiving chamber, and a cap provided at an opening of the bottle neck, a minimum width of the cap is larger than a width of a junction of the bottle neck and the cap, the medicine bottle handling device includes a penicillin bottle cap removing mechanism including a separating mechanism including a second base, a clamp plate provided at the second base and an elastic member, the clamp plate extending toward an outer periphery of the second base, and the clamp plate having a rear end relatively close to the second base, and a front end opposite to the rear end, the clamp plate being telescopically provided at the second base along an extending direction of the clamp plate by the elastic member, and when the penicillin bottle is cap removed, the medicine bottle cap removing mechanism moves the clamp plate away from the bottle body and away from the front end of the bottle neck by moving the clamp plate away from the bottle body surface. Under this kind of circumstances, can produce the effort towards cardboard rear end direction to the cardboard when xiLin bottle and cardboard contact, elastomeric element compresses tightly the shrink state because of the atress, compress tightly the elastomeric element of shrink and produce the reaction force towards the front end direction to the cardboard, when medicine bottle handling mechanism carries the bottle in order to make the bottle of xiLin bottle remove with the mode of keeping away from the bottle cap, elastomeric element's reaction force can make the cardboard kick-back, thereby make cardboard front end embedding bottle cap below and pry up the bottle cap, can follow the bottleneck separation with the bottle cap of xiLin bottle with full-automatic mode, thereby can improve xiLin bottle and go the efficiency of bottle cap.

According to the present disclosure, an automated liquid dispensing system capable of improving the dosing accuracy of the liquid dispensing system can be provided.

Drawings

The disclosure will now be explained in further detail by way of example with reference to the accompanying drawings, in which:

fig. 1 is an overall schematic diagram illustrating a liquid dispensing system according to an example of the present disclosure.

Fig. 2 is a schematic diagram illustrating a medicine bottle handling apparatus according to an example of the present disclosure.

Fig. 3 is a schematic diagram showing a medicine bottle handling mechanism according to an example of the present disclosure.

Fig. 4 is a schematic top view illustrating a vial clamping section according to an example of the present disclosure.

Fig. 5 is a schematic diagram showing a first grip driving section according to an example of the present disclosure.

Fig. 6 is a schematic diagram illustrating a first frame body according to an example of the present disclosure.

Fig. 7 is a schematic diagram illustrating a cartridge according to an example of the present disclosure.

Fig. 8 is a schematic diagram showing a blocking portion according to an example of the present disclosure.

Fig. 9 is a schematic diagram illustrating a touch portion to which examples of the present disclosure relate.

Fig. 10 is a schematic diagram illustrating an ampoule bottle to which examples of the present disclosure relate.

Fig. 11 is a schematic diagram illustrating an ampoule uncapping mechanism according to an example of the present disclosure.

Fig. 12 is an overall schematic diagram showing a scribing mechanism according to an example of the present disclosure.

Fig. 13 is a schematic diagram illustrating a bottle knocking mechanism according to an example of the present disclosure.

Fig. 14 is a schematic diagram showing a penicillin bottle according to an example of the present disclosure.

Fig. 15 is a schematic diagram showing a separation mechanism according to an example of the present disclosure.

Fig. 16 is a schematic view showing the abutting of the separation mechanism to the penicillin bottle according to the example of the present disclosure.

Fig. 17 is a schematic diagram showing a liquid bag processing apparatus according to an example of the present disclosure.

Fig. 18 is a schematic diagram showing a liquid bag mounting mechanism according to an example of the present disclosure.

Fig. 19 is a schematic view showing the structure of a second base according to an example of the present disclosure.

Fig. 20 is a schematic diagram illustrating an actuator according to an example of the present disclosure.

Fig. 21 is a schematic diagram showing a liquid bag transporting mechanism according to an example of the present disclosure.

Fig. 22A is a schematic view showing a liquid bag holding portion according to an example of the present disclosure.

Fig. 22B is a schematic diagram showing a second view angle of the liquid bag holding portion according to the example of the present disclosure.

Fig. 23 is a schematic diagram showing an inhaler according to an example of the present disclosure.

Fig. 24 is a schematic diagram showing an inhaler handling device according to an example of the present disclosure.

Fig. 25 is a schematic view showing an inhaler mounting mechanism according to an example of the present disclosure.

Fig. 26 is a schematic diagram showing a lane to which examples of the present disclosure relate.

Fig. 27 is a schematic diagram showing a feeding mechanism according to an example of the present disclosure.

Fig. 28 is a schematic diagram showing an inhaler handling mechanism according to an example of the present disclosure.

Fig. 29 is a partial schematic view showing an inhaler handling mechanism according to an example of the present disclosure.

Fig. 30 is a schematic view showing the suction and injection device according to the example of the present disclosure in the holding space.

Fig. 31 is a schematic view showing that the holding portion according to the example of the present disclosure is engaged with the accommodating portion.

Fig. 32 is a schematic diagram showing a calibration mechanism according to an example of the present disclosure.

Fig. 33 is a schematic diagram illustrating a cabinet to which examples of the present disclosure relate.

Fig. 34 is a schematic diagram illustrating external airflow through a cabinet in accordance with examples of the present disclosure.

Fig. 35 is a schematic diagram illustrating a dosing platform to which examples of the present disclosure relate.

Fig. 36 is a schematic diagram illustrating an operating platform and a magazine according to an example of the present disclosure.

Fig. 37 is a block diagram illustrating a configuration of a drug delivery platform according to an example of the present disclosure.

Fig. 38 is a schematic view showing a first monitoring mechanism provided to a cabinet according to an example of the present disclosure.

Detailed Description

The following description of the technical solutions in the embodiments of the present disclosure will be made clearly and completely with reference to the accompanying drawings in the embodiments of the present disclosure, and it is apparent that the described embodiments are only some embodiments of the present disclosure, not all embodiments. Based on the embodiments in this disclosure, all other embodiments that a person of ordinary skill in the art would obtain without making any inventive effort are within the scope of protection of this disclosure.

The present disclosure relates to a liquid dispensing system comprising a liquid dispensing device and a dosing platform. The liquid dispensing device can automatically dispense the medicine contained in the medicine bottle and the solution contained in the liquid bag through the injection aspirator. The dosing platform can be used for dosing the liquid dispensing devices in batches according to the liquid dispensing requirements.

In the present disclosure, the liquid dispensing system may also be referred to as a dispensing machine, a dispensing robot, a dispensing apparatus, an automated dispensing device, an automated liquid dispensing system, a liquid medicine dispensing device, a liquid medicine mixing device, or the like.

Hereinafter, a liquid dispensing system according to the present disclosure will be described in detail with reference to the accompanying drawings.

Fig. 1 is an overall schematic diagram showing a liquid dispensing system 1 according to an example of the present disclosure.

In this embodiment, referring to fig. 1, a dispensing system 1 may include a dispensing device 2 and a dosing platform 6. The liquid dispensing device 2 can carry the suction and injection device 8, the medicine bottle 3 and the liquid bag 4 and complete automatic liquid transfer (described later) between the medicine bottle 3 and the liquid bag 4 through the suction and injection device 8, thereby realizing automatic liquid dispensing. The dosing platform 6 may provide the dispensing device 2 with a vial 3 containing a drug (i.e. dosing) to allow the dispensing device 2 to complete dispensing as desired.

In some examples, the dispensing device 2 may include a vial processing device 100, a bag processing device 300, and an aspirator processing device 500 (see fig. 1). The medicine bottle handling apparatus 100 is capable of carrying the medicine bottles 3 to a predetermined position; the liquid bag processing apparatus 300 can place and convey the liquid bag 4 to a predetermined position; the syringe handling device 500 may place the syringe 8 on a carrier and carry it to a predetermined position, and then drive the syringe 8 to perform the sucking or injecting operation. In this case, the medicine contained in the medicine bottle 3 can be sucked up by the suction and injection device 8 and injected into the liquid bag 4 to dispense the medicine with the solution contained in the liquid bag 4, so that automatic liquid dispensing can be realized. In some examples, the dispensing of the medicament contained in the vial 3 with the solution contained in the fluid bag 4 may also be referred to as dispensing.

Fig. 2 is a schematic diagram illustrating a vial handling device 100 according to an example of the present disclosure. Fig. 3 is a schematic diagram showing a medicine bottle handling mechanism 20 according to an example of the present disclosure. Fig. 4 is a schematic plan view showing the medicine bottle holding portion 21 according to the example of the present disclosure. Fig. 5 is a schematic diagram showing the first grip driving section 26 according to the example of the present disclosure.

Hereinafter, for convenience of description, the direction in which the medicine bottle conveying mechanism 20 approaches the medicine bottle placing mechanism 10 is understood as the D1 direction, and correspondingly, the direction in which the medicine bottle conveying mechanism 20 is away from the medicine bottle placing mechanism 10 is understood as the D2 direction. And referring to the normal operation posture (for example, the medicine bottle placing mechanism 10 may be arranged in the horizontal direction, the medicine bottle carrying mechanism 20 may be moved toward or away from the medicine bottle placing mechanism 10 in the horizontal direction), the horizontal leftward direction in fig. 3 is understood as the D3 direction, and the horizontal rightward direction is understood as the D4 direction.

In some examples, the vial handling device 100 may include a vial handling mechanism 20 (see fig. 2). The medicine bottle carrying mechanism 20 is movable, and the medicine bottle 3 can be carried by moving the medicine bottle carrying mechanism 20.

In some examples, the vial handling device 100 may include a vial loading mechanism 10 (see fig. 2) for loading vials 3. In this case, the medicine bottle 3 can be stored in the liquid dispensing device 2 by the medicine bottle placing mechanism 10, and the medicine bottle 3 can be picked up by the medicine bottle conveying mechanism 20.

In some examples, the vial handling mechanism 20 may have a vial gripping portion 21 (see fig. 3). The vial holder 21 may releasably hold the vial 3.

In some examples, the vial handling mechanism 20 may include a first base 22 and a mounting plate 27 (see fig. 3). Wherein, mounting plate 27 can be provided to first base 22, and medicine bottle clamping portion 21 can be provided to mounting plate 27. The vial holder 21 is movable on the mounting plate 27 to hold the vial 3.

In some examples, the first base 22 may be a robotic arm. The first base 22 may be configured to be movable. For example, in the example shown in fig. 3, the first base 22 may move in the D1 direction, the D2 direction, the D3 direction, the D4 direction, the D5 direction, or the D6 direction. In this case, the first base 22 can drive the medicine bottle holding portion 21 to approach or separate from the medicine bottle 3 from a plurality of directions, whereby it is possible to facilitate picking up the medicine bottle 3 from a plurality of directions and carrying the medicine bottle 3 to a predetermined position.

In some examples, the mounting plate 27 may be disposed at an end of the first base 22. In some examples, an end of the first base 22 may spin about the rotation axis L. In some examples, the mounting plate 27 may be disposed on the first base 22 in a manner orthogonal to the rotation axis L. In this case, when the medicine bottle holding portion 21 is provided to the mounting plate 27, the medicine bottle holding portion 21 can be made to pick up the medicine bottle 3 from a plurality of angles.

In some examples, the end of the first base 22 proximate the mounting plate 27 may be rotated a predetermined angle to oscillate. In other words, the mounting plate 27 and the medicine bottle holding portion 21 provided on the mounting plate 27 can be swung at a predetermined angle. In this case, after the medicine bottle 3 is held by the medicine bottle holding portion 21 and the medicine to be mixed is injected into the medicine bottle 3, the medicine in the medicine bottle 3 can be sufficiently mixed by repeatedly swinging the medicine bottle 3. In addition, the orientation of the mouth of the medicine bottle 3 can be adjusted by rotating the first base 22 at a preset angle.

In some examples, referring to fig. 4, vial clamping section 21 may include a first arm 211, a second arm 212, and a central arm 213. Wherein the central arm 213 may be disposed between the first arm 211 and the second arm 212.

In some examples, vial clamp 21 may have an open state and a clamped state. Referring to fig. 4, when the vial holder 21 is switched to the open state, the central arm 213 may move in the direction D2, the first arm 211 may move in the direction D3, and the second arm 212 may move in the direction D4. In this case, the medicine bottle 3 holding space a can be enlarged, so that the medicine bottle holding portion 21 can release the medicine bottle 3 located in the medicine bottle 3 holding space a. When the vial holder 21 is switched to the holding state, the central arm 213 may move in the direction D1, the first arm 211 may move in the direction D4, and the second arm 212 may move in the direction D3. In this case, the medicine bottle 3 holding space a can be reduced until the central arm 213, the first arm 211, and the second arm 212 abut against the medicine bottle 3, so that the medicine bottle holding portion 21 can hold the medicine bottle 3 located in the medicine bottle 3 holding space a.

In some examples, the vial handling mechanism 20 may include a gripping drive 26 (see fig. 5). The grip driving part 26 may be used to drive the movement of the medicine bottle gripping part 21 to cause the medicine bottle gripping part 21 to grip or release the medicine bottle 3. For convenience of description, the grip driving part 26 of the medicine bottle handling mechanism 20 will be referred to as a first grip driving part 26.

In some examples, the first clamp drive 26 may be provided on a mounting plate 27 (see fig. 3). In some examples, the first arm 211 and the second arm 212 may be disposed on the first clamp drive 26.

In some examples, referring to fig. 5, the first clamping drive 26 may include a slide, a first slider 261, and a second slider 262. For convenience of description, the slider of the first clamp driving portion 26 will be referred to as a first slider 260.

In some examples, the first clamp drive 26 may be used to drive the vial clamp 21 to switch between an open state and a clamped state. Specifically, the driving vial clamping section 21 may be switched to the open state by driving the first slider 261 and the second slider 262 away from each other along the first slider 260, and the driving vial clamping section 21 may be switched to the clamped state by driving the first slider 261 and the second slider 262 toward each other along the first slider 260.

In some examples, the vial handling mechanism 20 may further include an actuator 23 (see fig. 3), and the actuator 23 may cooperate with a magazine 12 (described later) of the vial loading mechanism 10 to cause the vial handling mechanism 20 to retrieve a vial 3 from the vial loading mechanism 10.

Fig. 6 is a schematic diagram showing the first frame 11 according to the example of the present disclosure. Fig. 7 is a schematic diagram illustrating a cartridge 12 according to an example of the present disclosure. Fig. 8 is a schematic diagram showing the blocking portion 13 according to the example of the present disclosure. Fig. 9 is a schematic diagram showing the touch portion 23 according to an example of the present disclosure.

In some examples, the vial loading mechanism 10 may include a frame 11 (see fig. 6) and a magazine 12 (see fig. 7). Wherein the medicine cartridge 12 may be detachably assembled to the frame 11. For convenience of description, the frame 11 of the medicine bottle mounting mechanism 10 will be referred to as a first frame 11.

In some examples, the first housing 11 may be fitted with a plurality of cartridges 12. Specifically, the first housing 11 may include a plurality of magazine bays 110 (one of the plurality of magazine bays 110 is schematically identified in fig. 6), and one magazine bay 110 may be used to house one magazine 12.

In some examples, referring to fig. 7, the cartridge 12 may have a vial magazine 120, and the vial magazine 120 may be used to house vials 3. In some examples, the vial magazine 120 may contain a plurality of vials 3. In some examples, the cartridge 12 may have a plurality of drug vial bins 120 (one of the plurality of drug vial bins 120 is schematically illustrated in fig. 7).

In some examples, the vial magazine 120 may include a bottom plate 123, and first and second side plates 121 and 122 disposed on opposite sides of the bottom plate 123, respectively (see fig. 7). In this case, the moving path of the medicine bottles 3 can be defined by the first side plate 121, the second side plate 122, and the bottom plate 123 to smoothly and orderly move the medicine bottles 3 within the medicine bottle bin 120.

In some examples, the vial loading mechanism 10 further includes a blocking portion 13 and a pushing portion 14 disposed within the vial magazine 120 (see fig. 7).

In some examples, the pushing portion 14 may be used to push the vial 3 to move the vial 3 in a direction toward the mouth of the vial magazine 120. The blocking portion 13 may be used to block the vial 3 so that the vial 3 is located in the vial magazine 120 when not picked up. In this case, when the blocking portion 13 is opened, the medicine bottle 3 can be conveniently moved from the inside of the medicine bottle bin 120 to the bin opening of the medicine bottle bin 120 by the pushing portion 14, thereby facilitating the pickup of the medicine bottle 3 in cooperation with the medicine bottle handling mechanism 20.

In some examples, the barrier 13 may be disposed at the mouth of the vial compartment 120 (fig. 7 schematically illustrates the barrier 13 disposed at the mouth of one vial compartment 120), and the barrier 13 may open or close the mouth of the vial compartment 120. In other words, the opening of the vial magazine 120 can be opened or closed by opening or closing the stopper 13.

In some examples, referring to fig. 7, the pushing portion 14 may be movably disposed in the vial housing 120, and the movable pushing portion 14 may apply a pushing force to the vials 3 within the vial housing 120. Specifically, the pushing portion 14 is movable in a direction from the rear to the mouth of the medicine bottle cartridge 120 (also referred to as a first direction), thereby exerting a pushing action in the first direction on the medicine bottles 3 in the medicine bottle cartridge 120.

In some examples, referring to fig. 8, the blocking portion 13 may include a movable member 130, a transmission member 132, and a return member 134. The movable member 130 may be removably disposed at the mouth of the vial holder 120. The drive member 132 (also referred to as a first drive member 132) can be coupled to the movable member 130 and provide a service function that moves the movable member 130 away from the mouth of the vial magazine 120. The return member 134 may be in linkage with the movable member 130 and serve to apply a return action to the movable member 130 that returns the movable member 130 to the mouth of the vial holder 120. In this case, by applying a force to the first transmission member 132, the movable member 130 can be moved away from the mouth of the medicine bottle bin 120, thereby facilitating the medicine bottle handling mechanism 20 to pick up the medicine bottle 3; after the medicine bottle handling mechanism 20 picks up the medicine bottle 3, the movable member 130 can be returned to the mouth of the medicine bottle bin 120 by the return member 134.

In some examples, the first transmission member 132 can be movable along the extension direction (i.e., the D1 direction) of the drug vial cartridge 120 to prevent the movable member 130 from moving away from the mouth of the drug vial cartridge 120 (see fig. 8). Thereby, the medicine bottle 3 can be held in the medicine bottle bin 120.

In some examples, movable member 130 may be block-shaped. The movable member 130 may be rotatably disposed at the mouth of the medicine bottle cartridge 120 about the first shaft 131, wherein the first shaft 131 may be disposed at the first transmission member 132, and the first shaft 131 may be perpendicular to the length direction of the medicine bottle cartridge 120. Thereby, the movable member 130 can be removed from the mouth of the medicine bottle bin 120 by rotating.

In some examples, the blocking portion 13 may close when the movable member 130 rotates to abut the mouth of the vial magazine 120. In this case, the medicine bottle 3 is held in the medicine bottle bin 120. In some examples, the barrier 13 may open when the movable member 130 is rotated away from the mouth of the vial magazine 120. In this case, the vial 3 can be transferred out of the vial magazine 120.

In some examples, the first transmission member 132 may include a trigger post 1320, and a contact block 1322 (see fig. 8) that is in linkage with the trigger post 1320. The contact block 1322 may be disposed between the trigger post 1320 and the movable member 130. In some examples, the contact block 1322 may abut the trigger post 1320 and the movable member 130, and the contact block 1322 may be interlocked when the trigger post 1320 is forced to move such that the contact block 1322 applies an effect to the movable member 130.

In some examples, the trigger post 1320 may extend at least partially out of the mouth of the vial cartridge 120. Thereby, it can be facilitated to apply an action to the trigger post 1320 to open the blocking portion 13.

In some examples, the portion of the trigger post 1320 that protrudes from the mouth of the vial magazine 120 may be located on the path of travel of the trigger 23 when the vial handling mechanism 20 approaches the vial loading mechanism 10 (described later). In this case, the medicine bottle handling mechanism 20 can be made to pick up the medicine bottle 3 by opening the stopper 13 by the trigger 23 when approaching the medicine bottle placing mechanism 10.

In some examples, return member 134 may be a spring. In some examples, the return member 134 may be compressed when the movable member 130 is forced away from the mouth of the vial magazine 120. In this case, the compressed restoring member 134 can provide a restoring force to the movable member 130 to restore the movable member 130 to the mouth of the medicine bottle cartridge 120.

In some examples, the trigger portion 23 of the medicine bottle handling mechanism 20 may cooperate with the blocking portion 13 to open the mouth of the medicine bottle compartment 120, after which the medicine bottle 3 may be moved in the mouth direction of the medicine bottle compartment 120 due to the pushing action of the pushing portion 14 on the medicine bottle 3, and the medicine bottle clamping portion 21 of the medicine bottle handling mechanism 20 may clamp the medicine bottle 3 at the mouth of the medicine bottle compartment 120, so that the medicine bottle 3 is transferred from the medicine bottle loading mechanism 10 to the medicine bottle handling mechanism 20. In this case, when the medicine bottle 3 is picked up by the medicine bottle carrying mechanism 20, the mouth of the medicine bottle compartment 120 can be opened by the engagement between the trigger portion 23 and the stopper portion 13, and the medicine bottle 3 can be taken out easily.

In some examples, trigger 23 may include a mounting member 232, a trigger member 234, and a detection member 236 (see fig. 9). The trigger member 234 and the detection member 236 may be provided on the mounting member 232. The trigger member 234 can be configured to abut the trigger post 1320. The detection member 236 may be used to detect the position of the trigger member 234.

In some examples, the trigger member 234 may include a trigger post 234a and a trigger block 234b (see fig. 9). The touch member 234 may have a preset detection area. The predetermined detection area may be located at the touch post 234a.

In some examples, the predetermined detection area may be a notch formed on the touch post 234 a. The trigger block 234b may be disposed at an end of the trigger post 234a and may abut the trigger post 1320 when the trigger 23 opens the blocking portion 13.

In some examples, when trigger 23 is applied to trigger post 1320, trigger member 234 moves relative to mounting member 232 under the opposing action of trigger post 1320. In some examples, the position of the preset detection zone may correspond to the position of the trigger post 1320 when the movable member 130 is moved away from the position of the mouth of the vial holder 120. In other words, when the trigger 23 opens the blocking portion 13, the trigger member 234 may be moved to a predetermined position under the influence of the relative action of the trigger post 1320.

In some examples, the detection member 236 may have a detection region. The detection area may be used to detect a preset detection area of the touch post 234 a. Specifically, when the movable member 130 is moved away from the mouth of the medicine cartridge 120, the preset detection area of the trigger member 234 and the detection area of the detection member 236 may be at least partially overlapped. In other words, the detection area of the detection member 236 is located at a predetermined position to which the trigger member 234 moves under the influence of the relative action of the trigger post 1320. In this case, when the blocking portion 13 is opened, the detection area of the detection member 236 can detect the preset detection area of the touch member 234, so that whether the blocking portion 13 can be opened can be detected by the detection member 236.

In some examples, when trigger 23 applies an action to blocking portion 13, trigger member 234 may abut blocking portion 13, and trigger member 234 may move relative to detection member 236. Specifically, the trigger member 234 may apply a force to the blocking portion 13 to open the blocking portion 13 (i.e., open the mouth of the vial holder 120), while the trigger member 234 may move relative to the detection member 236 under the reaction force of the blocking portion 13 such that the predetermined detection area of the trigger member 234 at least partially overlaps the detection area of the detection member 236. In this case, when the blocking portion 13 is opened by the touch portion 23, the preset detection area of the touch member 234 moves to the detection area of the detection member 236 so that the detection area of the detection member 236 can detect the preset detection area of the touch member 234, thereby enabling confirmation by the detection member 236 whether the blocking portion 13 has been opened.

Fig. 10 is a schematic diagram showing an ampoule 3a to which the example of the present disclosure relates. Fig. 11 is a schematic diagram illustrating ampoule uncapping mechanism 24 according to an example of the present disclosure. Fig. 12 is an overall schematic diagram showing a scribing mechanism 242 according to an example of the present disclosure. Fig. 13 is a schematic diagram illustrating a bottle-knocking mechanism 244 according to an example of the present disclosure. Fig. 14 is a schematic diagram showing a penicillin bottle 3b according to an example of the present disclosure. Fig. 15 is a schematic diagram showing a separation mechanism 250 according to an example of the present disclosure. Fig. 16 is a schematic view showing that the separation mechanism 250 according to the example of the present disclosure abuts against the penicillin bottle 3 b.

In some examples, referring to fig. 10, the vial 3 may be an ampoule 3a, and the ampoule 3a may include a body portion 31a, a cap 33a, and a neck 35a. Wherein a neck 35a may connect the body portion 31a and the cap 33a.

In some examples, the vial handling device 100 may include an ampoule uncapping mechanism 24, and the ampoule uncapping mechanism 24 may be used to remove the caps 33a of the ampoule 3a.

In some examples, ampoule uncapping mechanism 24 may include a scoring mechanism 242 and a knockout mechanism 244 (see fig. 11). The cutting mechanism 242 may cut the bottleneck 35a of the ampoule 3a, and the knocking mechanism 244 may knock the cut ampoule 3a to remove the cap 33a.

In some examples, referring to fig. 12, the scribing mechanism 242 may include a rotation portion 2420 having a cutter wheel 2422, and the cutter wheel 2422 may be rotated at a preset rotational speed by the rotation portion 2420. In this case, the ampoule 3a can be easily scribed by the cutter wheel 2422 rotating at a high speed.

In some examples, referring to fig. 13, the knockout mechanism 244 may have a first base 2442 and a thin lever 2444, wherein the thin lever 2444 may be rotatably disposed to the first base 2442. In this case, the thin rod 2444 can be made to tap the scribed ampoule 3a in a rotating manner to remove the cap 33a, so that the convenience of removing the cap 33a can be improved.

In some examples, ampoule uncapping mechanism 24 may have a bottle cutting station and a bottle knocking station. Wherein the scoring mechanism 242 may be located at a bottle cutting station and the striking mechanism may be located at a bottle striking station.

In some examples, upon removal of the cap 33a from the ampoule 3a, the vial handling mechanism 20 may handle the vial 3 to a vial cutting station and the cutter wheel 2422 may be rotated to score the vial neck 35 a; the vial handling mechanism 20 may handle the scored vial 3 to a knockout station and the thin lever 2444 may rotate and knock the cap 33a to separate the cap 33a from the neck 35 a. Thereby, the cap 33a of the ampoule 3a can be automatically removed.

In some examples, when the thin rod 2444 taps the cap 33a, the thin rod 2444 may tap the cap 33a at least once in a manner that rotates about the first mount 2442. For example, the thin rod 2444 may make two taps on the cap 33a, the first tap may separate the cap 33a from the neck 35a, and the second tap may be used to confirm whether the cap 33a has been removed.

In the ampoule bottle cap removing mechanism 24 according to the present disclosure, firstly, the ampoule bottle 3a is moved to the bottle cutting station, the bottle neck 35a of the ampoule bottle 3a is cut by the cutting mechanism 242, then, the cut ampoule bottle 3a is moved to the bottle knocking station, and the bottle cap 33a is knocked by the bottle knocking mechanism 244 to separate the bottle cap 33a from the bottle neck 35a, so that the bottle cap 33a of the ampoule bottle 3a can be separated from the bottle neck 35a in a fully automatic manner, and the efficiency of removing the bottle cap 33a from the ampoule bottle 3a can be improved.

In some examples, the vial 3 may be a penicillin vial 3b, and the penicillin vial 3b may include a vial body 32b, a bottleneck 34b, and a cap 36b disposed at an opening 2510 of the bottleneck 34b (see fig. 14). Wherein the minimum width of the cap 36b may be greater than the width of the neck 34b at the junction with the cap 36 b. In some examples, the bottle 32b may have a receiving chamber and the neck 34b may have a hollow passage in communication with the receiving chamber.

In some examples, the vial handling device 100 may include a penicillin bottle cap removal mechanism 25, and the penicillin bottle cap removal mechanism 25 may be used to remove the caps 36b of the penicillin bottles 3 b.

In some examples, referring to fig. 15, penicillin bottle cap removal mechanism 25 may include a housing 251 and a separation mechanism 250, wherein housing 251 may be housed outside separation mechanism 250, and housing 251 may have an opening 2510 for penicillin bottle 3b to enter and exit.

In some examples, separation mechanism 250 may include a second base 252, a catch plate 254, and a resilient member 256 (see fig. 16). Wherein, cardboard 254 and elastic member 256 may be provided on second base 252.

In some examples, catch plate 254 may be plate-shaped and catch plate 254 may extend toward the periphery of second base 252. In some examples, catch plate 254 may have a rear end V1 that is relatively close to second base 252, and a front end V2 opposite rear end V1 (see fig. 16). In some examples, catch plate 254 may be telescopically disposed on second base 252 along the direction of extension of catch plate 254 by resilient member 256.

In some examples, when uncapping penicillin bottle 3b, vial handling mechanism 20 may handle vial 3 such that the lower surface of cap 36b abuts the upper surface of front end V2 of clamp plate 254, and vial handling mechanism 20 may urge the body of penicillin bottle 3b to move away from cap 36b, thereby separating cap 36b from bottleneck 34 b. Thereby, the cap 36b of the penicillin bottle 3b can be automatically removed.

In the penicillin bottle cap removing mechanism 25 according to the present disclosure, when the penicillin bottle 3b contacts with the clamp plate 254, a force is generated to the clamp plate 254 in the direction toward the rear end V1 of the clamp plate 254, the elastic member 256 is in a compressed and contracted state due to the force, the elastic member 256 compressed and contracted generates a reaction force to the clamp plate 254 in the direction toward the front end V2, when the medicine bottle handling mechanism 20 carries the medicine bottle 3 so that the body 32b of the penicillin bottle 3b moves away from the cap 36b, the reaction force of the elastic member 256 can rebound the clamp plate 254, so that the front end V2 of the clamp plate 254 is embedded under the cap 36b to pry up the cap 36b, thereby separating the cap 36b of the penicillin bottle 3b from the bottleneck 34b in a fully automatic manner, and improving the efficiency of removing the cap 36b from the penicillin bottle 3 b.

Fig. 17 is a schematic diagram showing a liquid bag processing apparatus 300 according to an example of the present disclosure. Fig. 18 is a schematic diagram showing a liquid bag mounting mechanism 30 according to an example of the present disclosure. Fig. 19 is a schematic view showing the structure of the second pedestal 32 according to the example of the present disclosure. Fig. 20 is a schematic diagram illustrating an actuator 34 according to an example of the present disclosure. Fig. 21 is a schematic diagram showing a fluid bag carrying mechanism 40 according to an example of the present disclosure. Fig. 22A is a schematic diagram showing the liquid bag holding portion 46 according to the example of the present disclosure. Fig. 22B is a schematic diagram showing a second view angle of the liquid bag holding portion 46 according to the example of the present disclosure.

As described above, the liquid dispensing apparatus 2 may further include the liquid bag processing apparatus 300, and the liquid bag processing apparatus 300 may place the liquid bag 4 necessary for dispensing the liquid and convey the liquid bag 4 to a predetermined position.

In some examples, referring to fig. 17, the fluid bag handling apparatus 300 may include a fluid bag placement mechanism 30 for placing the fluid bags 4. In some examples, the fluid bag 4 may be transported along the transport path by the fluid bag loading mechanism 30. This facilitates the pickup of the liquid bag 4 by the liquid bag carrying mechanism 40.

In some examples, referring to fig. 17, the fluid bag handling apparatus 300 may include a fluid bag handling mechanism 40 for handling fluid bags 4. In some examples, the fluid bag handling mechanism 40 may be movable, and the fluid bag 4 may be handled to a predetermined position by movement of the fluid bag handling mechanism 40.

In some examples, the fluid bag loading mechanism 30 may include a base 32 and an actuator 34 (see fig. 21). For convenience of description, the base 32 of the liquid bag loading mechanism 30 will be referred to as a second base 32, and the second base 32 may be disposed along the conveying path and may be used to load the liquid bag 4. The actuator 34 may be used to apply an action to the infusion bag 4 on the second base 32 to move the bag 4 along the transport path.

In some examples, the transport path may be a path that the liquid bag 4 passes through during movement. For example, in the example shown in fig. 18, the conveyance path may extend in the predetermined direction c.

In some examples, referring to fig. 18, the second base 32 may have a pouch compartment 320, the pouch compartment 320 may extend in a predetermined direction c, and the pouch compartment 320 may form a conveying path. In some examples, the second base 32 may have a plurality of fluid bag pockets 320.

In some examples, the second base 32 may include oppositely disposed first and second support members 322, 324 (see fig. 19). The first support member 322 may cooperate with the second support member 324 to form a pouch pocket 320 for carrying a pouch 4.

In some examples, the fluid bag cartridge 320 may be a gap between the first support member 322 and the second support member 324 (see fig. 19). In some examples, the neck 420 of the fluid bag 4 may be at least partially positioned in the fluid bag compartment 320 when the second base 32 carries the fluid bag 4 (see fig. 18). In addition, neck 420 of pouch 4 may include a first neck 420a and a second neck 420b.

In some examples, the second base 32 may also include a third support member 325 (see fig. 19). The second support mechanism may cooperate with the third support mechanism to form a fluid bag cartridge 320.

In some examples, the pouch mounting mechanism 30 may also include a blocking mechanism 36 (see fig. 18). The blocking mechanism 36 may be arranged in an openable and closable manner on the conveying path. When the blocking mechanism 36 is opened, the liquid bag 4 may pass through the blocking mechanism 36 on the conveying path; when the blocking mechanism 36 is closed, the blocking mechanism 36 blocks the movement of the liquid bag 4 on the conveying path.

In some examples, the blocking mechanism 36 may be located at the aft f of the bag house 320 (see fig. 19). In this case, the liquid bag 4 can be moved out of or held in the liquid bag magazine 320 by opening or closing the blocking mechanism 36, thereby facilitating the liquid bag handling mechanism 40 to pick up the liquid bag 4 at the magazine tail f.

In some examples, the actuator 34 of the liquid bag loading mechanism 30 may include a contact member 340 and a drive member 342 (see fig. 20). The contact member 340 may be in contact with the liquid bag 4 and the driving member 342 may drive the contact member 340 to move so that the contact member 340 pushes the liquid bag 4 to move on the conveying path.

In some examples, the contact member 340 may contact the neck 420 of the fluid bag 4 to push the fluid bag 4.

In some examples, the drive member 342 may be a belt conveyor mechanism. The belt of the driving member 342 may be disposed along the predetermined direction c. The belt of the driving member 342 may be interlocked with the contact member 340. Thereby, the contact member 340 can be driven to move by the driving member 342.

In some examples, the actuator 34 may also include a transmission member 344 (see fig. 20). A transmission member 344 (also referred to as a second transmission member 344) may be used to connect the contact member 340 and the drive member 342. In some examples, a belt of the drive member 342 may be provided to the second transmission member 344. The contact member 340 may be provided to the second transmission member 344 (see fig. 20). In some examples, the contact member 340 may be moved away from the transport path in a manner that rotates about a fixed axis. Thereby, the liquid bag 4 can be facilitated to enter the conveying path.

In some examples, the fluid bag handling mechanism 40 may include a base 42 (also referred to as a third base 42), a cradle 44, and a fluid bag clamp 46 (see fig. 21). Wherein the fluid bag clamping portion 46 may include a first clamping portion 462 and a second clamping portion 464 (see fig. 22A). The first clamping portion 462 and the second clamping portion 464 may be disposed on the support base 44. The first clamping portion 462 and the second clamping portion 464 may cooperate to clamp the fluid bag 4. The bearing block 44 may be rotatably disposed on the third base 42. In some examples, the first clamping portion 462 and the second clamping portion 464 may respectively abut against opposite sides of the neck 420 of the fluid bag 4 to clamp the fluid bag 4.

In some examples, the support base 44 may be rotated to rotate the fluid bag 4 held by the first holding portion 462 and the second holding portion 464 to turn the fluid bag 4 from the state shown in fig. 21 to the state in which the fluid outlet is directed downward. In this case, the solution in the liquid bag 4 can be concentrated in the vicinity of the liquid outlet of the liquid bag 4 by the action of gravity, and the needle tube 84 of the syringe 8 can thereby be facilitated to obtain the liquid medicine in the liquid bag 4.

In some examples, the third mount 42 may be a robotic arm 612 (described later). The third base 42 can be moved in a translational or rotational manner to move the first and second clamping portions 462, 464 on the support base 44.

In some examples, the fluid bag handling mechanism 40 may also include suction cups 48 (see fig. 21). The suction cup 48 may be used to suction the body of the fluid bag 4. In some examples, the suction cup 48 may be attached to the receptacle 71 of the fluid bag 4. In this case, the infusion bag 4 can be fixed by the suction cup 48, so that the infusion bag 4 can be turned over more stably. In some examples, the suction cup 48 may be in communication with a vacuum pump, which may be used to draw air between the suction cup 48 and the receptacle 71 to create a negative pressure between the suction cup 48 and the receptacle 71. This can improve the firmness of the suction cup 48 for sucking the liquid bag 4.

In some examples, referring to fig. 22B, the first clamp 462 can include a first clamp arm 462a and a second clamp arm 462B. The second clamping portion 464 may include a third clamping arm 464a and a fourth clamping arm 464b. The first clamping arm 462a may cooperate with the third clamping arm 464a to clamp the first neck 420a of the fluid bag 4 and the second clamping arm 462b may cooperate with the fourth clamping arm 464b to clamp the second neck 420b of the fluid bag 4. This can improve the firmness of the holding liquid bag 4.

In some examples, the fluid bag handling mechanism 40 may also include a clamp drive 47 (see fig. 22A). The clamping drive portion 47 may be used to drive the first clamping portion 462 and the second clamping portion 464 to move relative to each other such that the first clamping portion 462 and the second clamping portion 464 clamp or release the neck 420 of the fluid bag 4.

In some examples, referring to fig. 22B, the clamp driving portion 47 may include a slider 470, a first slider 471, and a second slider 472. The first slider 471 and the second slider 472 may be connected with the tongue and groove of the slider 470. Thereby, the first slider 471 and the second slider 472 can be made to move on the carriage 470 in the predetermined direction c.

In some examples, the first slider 471 may be interlocked with the first clamp 462. The second slider 472 may be interlocked with the second clamping portion 464. In some examples, the first slider 471 may be moved closer to the second slider 472 to move the first clamping portion 462 and the second clamping portion 464 closer to each other to clamp the neck 420 of the liquid bag 4. In some examples, the first slider 471 may be moved away from the second slider 472 to move the first clamping portion 462 and the second clamping portion 464 away from each other to release the neck 420 of the liquid bag 4. In some examples, the first slider 471 may be interlocked with the second slider 472.

In the liquid bag transporting mechanism 40 according to the present disclosure, the liquid bag 4 can be made to have a predetermined angle with respect to the vertical direction by rotating the support base 44, so that the suction and injection device 8 can transfer the liquid medicine in cooperation with the liquid bag 4 at the same predetermined angle, and thus the manual pipetting operation can be simulated to the maximum extent. In addition, the suction cup 48 is used for sucking the liquid bag 4, so that the stability of the liquid bag 4 during rotation can be improved, and the liquid bag 4 and the suction and injection device 8 can be conveniently matched for pipetting.

Fig. 23 is a schematic diagram showing the inhaler 8 according to the example of the present disclosure. Fig. 24 is a schematic diagram illustrating an inhaler handling device 500 according to an example of the present disclosure. Fig. 25 is a schematic view showing an inhaler mounting mechanism 50 according to an example of the present disclosure. Fig. 26 is a schematic diagram showing a lane 52 to which examples of the present disclosure relate. Fig. 27 is a schematic diagram showing a feeding mechanism 54 according to an example of the present disclosure. Fig. 28 is a schematic diagram showing an inhaler handling mechanism 60 according to an example of the present disclosure. Fig. 29 is a partial schematic view showing an inhaler handling mechanism 60 according to an example of the present disclosure. Fig. 30 is a schematic view showing that the suction and injection device 8 according to the example of the present disclosure is located in the holding space. Fig. 31 is a schematic view showing that the holding portion 823 according to the example of the present disclosure is engaged with the accommodating portion 71.

As described above, the liquid dispensing apparatus 2 may further include the pipette handling apparatus 500, and the pipette handling apparatus 500 may automatically pick up the pipettes 8 and automatically aspirate or infuse the liquid.

In this embodiment, the inhaler 8 may be used for mixing and dispensing of an infusion drug, and specifically, the inhaler 8 may aspirate and inject the infusion drug. In some examples, the injector 8 may include an injection tube 80, a core 82, and a needle cannula 84 (see fig. 23). In the present disclosure, the syringe 80, the core 82, and the needle cannula 84 of the syringe 8 may be coaxially disposed.

In some examples, syringe 80 may have a receiving chamber and core 82 may have a shaft, a piston disposed at one end of the shaft and within syringe 80, and a grip 823 at the other end of the shaft. In some examples, grip 823 may be located at an end of core 82 opposite needle cannula 84 (see FIG. 23). Core 82 may be movably disposed within the interior cavity of syringe 80.

In some examples, needle cannula 84 may be coupled to one end of injection tube 80, and needle cannula 84 may be in communication with a receiving chamber of injection tube 80.

In some examples, the end of the syringe 80 opposite the needle cannula 84 may have a flange 88 (see fig. 23). In some examples, flange 88 may be an outwardly extending portion of the outer wall of syringe 80.

In some examples, the syringe handling device 500 may include a syringe placement mechanism 50 (see fig. 24), and the syringe placement mechanism 50 may be used to place the syringe 8.

In some examples, the syringe handling device 500 may include a syringe handling mechanism 60 (see fig. 24) for handling the syringe 8. The syringe carrier mechanism 60 is movable, and the syringe 8 can be carried to a predetermined position by the movement of the syringe carrier mechanism 60.

In some examples, referring to fig. 28, the pipettor processing device 500 may include a pipetting mechanism 70, and the pipetting mechanism 70 may be disposed on the pipettor handling mechanism 60. In some examples, the pipetting mechanism 70 may control the pipettor 8 to pipette between the vial 3 and the fluid bag 4. In particular, pipetting mechanism 70 may be used to push core 82 into movement within the receiving chamber of syringe 80. Thus, the pipetting mechanism 70 can control the pipetting device 8 to perform pipetting, thereby realizing automated pipetting and pipetting.

In some examples, the syringe placement mechanism 50 may deliver the syringe 8 along a delivery path. In some examples, the syringe mount mechanism 50 may include a chute 52 and a feed mechanism 54 (see fig. 25). Wherein the chute 52 may extend along a conveying path and the chute 52 has an inlet 521 and an outlet 522 (see fig. 26) for movement of the pipettor 8, the feed mechanism 54 may be configured to receive the pipettor 8 delivered by the outlet 522 and to transport the pipettor 8 to a feed position N2 (shown later).

In some examples, the syringe mount mechanism 50 may include a frame 53 (see fig. 25). The frame 53 is a holder for carrying the material path 52 and the feeding mechanism 54. For convenience of description, the frame 53 of the suction and injection device mounting mechanism 50 will be referred to as a second frame 53.

In some examples, the chute 52 may have an inlet 521 and an outlet 522 (see fig. 26) for movement of the suction injector 8. The syringe mounting mechanism 50 can convey the syringe 8 along a conveyance path from the inlet 521 to the outlet 522.

In some examples, the height of the inlet 521 of the chute 52 may be greater than the height of the outlet 522 to form an inclined downward chute 52. In this case, the suction and injection device 8 can be easily slid freely to the outlet 522 by its own gravity on the material path 52.

In some examples, the lane 52 may include a first slide rail 523a and a second slide rail 523b disposed in parallel (see fig. 26).

In some examples, the spacing between the first and second slide rails 523a, 523b may be greater than the outer diameter of the syringe 80 and less than the minimum width of the flange 88 of the syringe 80. In this case, the body of the syringe 80 may extend between the first slide rail 523a and the second slide rail 523b, and the flange 88 of the syringe 80 may rest on the first slide rail 523a and the second slide rail 523b, thereby enabling the inhaler 8 to easily slide freely on the material path 52 to the outlet 522 by self gravity.

In some examples, as described above, the syringe loading mechanism 50 may include a feeding mechanism 54 that may transport the syringe 8 to the feeding position N2. In some examples, the feed position N2 may be a position where the suction injector handling mechanism 60 is available to take material (see fig. 27).

In some examples, the feed mechanism 54 may include a rotating disc 542 and a base 544 (also referred to as a fourth base 544) (see fig. 27). Wherein the fourth mount 544 may be used to support the rotating disk 542, the rotating disk 542 may be rotatably disposed on the fourth mount 544.

In some examples, the rotating disc 542 can have a body portion 5420 and a material handling indentation 5422 (see fig. 27). The material transport gap 5422 may be used for mounting the suction syringe 8. In this case, the suction syringe 8 fed out from the outlet 522 of the lane 52 can be received by the rotating disc 542 with the transport gap 5422; the suction syringe 8 mounted on the transport gap 5422 can be moved from the initial position N1 to the feeding position N2 by rotating the rotating plate 542 with the position of the transport gap 5422 facing the outlet 522 as the initial position N1.

In some examples, the pipettor handling mechanism 60 may include a carrier 61 and an pipettor clamp 62 (see fig. 28). The suction and injection device holding portion 62 may be provided on the carrying table 61, and the suction and injection device holding portion 62 may be used to hold the suction and injection device 8.

In some examples, the carrier 61 may be configured to be movable. For example, the stage 61 may be moved along a preset path.

In some examples, the carrier 61 may include a movable robotic arm 612, and a third base 614 (see fig. 28) disposed on the robotic arm 612. The pipette holder 62 and pipetting mechanism 70 may be disposed on the third pedestal 614 and the third pedestal 614 may be moved by driving the robotic arm 612 to move.

In some examples, the suction and injector clamp 62 may include a first clamp assembly 621, and a second clamp assembly 622 (see fig. 29) that is movable toward and away from the first clamp assembly 621.

In some examples, the first grip assembly 621 and the second grip assembly 622 may cooperate to form a grip space X (see fig. 30) that mates with the syringe 80.

In some examples, when the pipettor clamp 62 picks up the pipettor 8, the carrier 61 may be driven to move toward the pipettor 8 to bring the pipettor 8 into the clamp space X (see fig. 30), and the first and second clamp assemblies 621 and 622 may be moved toward each other to bring the first and second clamp assemblies 621 and 622 into abutment with the syringe 80, respectively, to complete the clamping of the syringe 80.

In some examples, as described above, the pipettor processing apparatus 500 may include a pipetting mechanism 70, where the grip 823 of the pipettor 8 may be located within the pipetting mechanism 70 when the pipettor 8 is picked up by the pipettor handling mechanism 60, and the pipetting mechanism 70 may be used to push the plunger 82 to aspirate or infuse the pipettor 8 to automate pipetting and pipetting. In some examples, the pipetting mechanism 70 may be movable along the length of the core 82 (e.g., in the F1 and F2 directions with the pipettor 8 in the vertical position in FIG. 31).

In some examples, the pipetting mechanism 70 may include a receptacle 71 having a recess (see fig. 31). In the present disclosure, the groove of the receiving portion 71 will be referred to as a first groove 712 for more clear description.

In some examples, the first groove 712 may match the outer contour of the grip 823 of the inhaler 8. When the pipettor handling mechanism 60 picks up the pipettor 8, the grip 823 may be located within the first groove 712. In this case, the drive housing 71 can be moved in the longitudinal direction of the plunger 82 to drive the plunger 82 to move in the longitudinal direction of the syringe 80 to perform liquid suction or liquid injection.

Fig. 32 is a schematic diagram showing a calibration mechanism 90 according to an example of the present disclosure.

In some examples, the pipettor processing apparatus 500 may include a calibration mechanism 90 for calibrating the position of the pipettor 8. In this case, the movement route can be planned based on the calibration coordinates of the inhaler 8 so that the inhaler 8 can be accurately moved to a predetermined position to perform inhalation of the medicine in cooperation with the target container such as the medicine bottle 3 or the liquid bag 4.

In some examples, the calibration mechanism 90 may have a calibration area H (see fig. 32). The pipettor 8 may be placed within the calibration area H and the pipettor 8 calibrated by the calibration mechanism 90. Specifically, when the pipettes 8 are carried, it is necessary to move the needle tube 84 of the pipettes 8 to a predetermined position to perform the pipetting of the medicine in cooperation with the container such as the medicine bottle 3, the liquid bag 4, etc., and when the pipettes 8 are picked up by the pipetter carrying mechanism 60, since there may be a slight difference in the posture angle of each of the pipettes 8, the needle tube 84 of the pipettes 8 may be placed in the calibration area H at this time, and the position of the needle tube 84 (i.e., the calibration coordinate value of the needle tube 84) may be acquired by the calibration mechanism 90. In this case, a moving route can be planned by the calibration mechanism 90 based on the calibration coordinate values of the needle tube 84 to move the syringe 8 to a predetermined position, so that accurate alignment of the syringe 8 with a target container (e.g., the medicine bottle 3 or the liquid bag 4) can be achieved.

In some examples, the calibration mechanism 90 may include a first camera 91 and a second camera 92 having optical axes perpendicular to each other, and the photographing view of the first camera 91 may cooperate with the photographing view of the second camera 92 to form a calibration area H (see fig. 32). That is, the calibration area H may be an area formed at the intersection of the exit optical axis A1 of the first camera 91 and the exit optical axis A2 of the second camera 92 and may be photographed by both the first camera 91 and the second camera 92 (see fig. 32). In this case, the image position information of the needle tube 84 can be acquired by the first camera 91 and the second camera 92, thereby being converted into the calibration coordinate values. In some examples, the image position information of the needle cannula 84 may be converted into calibrated coordinate values of the needle cannula 84 based on camera calibration principles.

In some examples, the dispensing device 2 may have a pipetting station. The pipetting station may be located in a region where the movement tracks of the three mechanisms 20, 40 and 60 overlap.

Specifically, the dispensing device 2 may have a first pipetting station and a second pipetting station, the first pipetting station may be located in a region where the movement trajectories of the medicine bottle handling mechanism 20 and the pipette handling mechanism 60 can overlap, and the second pipetting station may be located in a region where the movement trajectories of the liquid bag handling mechanism 40 and the pipette handling mechanism 60 can overlap. During dispensing, the medicine bottle handling mechanism 20 can clamp the medicine bottle 3 and move the medicine bottle 3 to the first pipetting station, the liquid bag handling mechanism 40 can clamp the liquid bag 4 and move the liquid bag 4 to the second pipetting station, the suction and injection device handling mechanism 60 can clamp the suction and injection device 8 and move the suction and injection device 8 between the first pipetting station and the second pipetting station, and the pipetting mechanism 70 controls the suction and injection device 8 to perform pipetting between the medicine bottle 3 and the liquid bag 4. In this case, at the first pipetting station, the pipetting mechanism 70 is enabled to control the pipetting device 8 to aspirate medicine from the medicine bottle 3 or to infuse solution into the medicine bottle 3 by the cooperation between the medicine bottle handling mechanism 20 and the pipetting device handling mechanism 60; at the second pipetting station, the pipetting mechanism 70 is enabled to control the pipettor 8 to inject medicine into the fluid bag 4 or to aspirate solution from the fluid bag 4 by cooperation between the fluid bag handling mechanism 40 and the pipettor handling mechanism 60. This allows the pipette 8 to automatically pipette between the vial 3 and the bag 4.

In some examples, when dispensing liquid, the liquid bag handling mechanism 40 may rotate the support base 44 to make the liquid bag 4 form a predetermined angle with the vertical direction after clamping the liquid bag 4, and the sucker 48 may adsorb the liquid bag 4 at the predetermined angle with the vertical direction of the liquid bag 4. In this case, the manual pipetting operation can be simulated to the maximum. In addition, the suction cup 48 is used for sucking the liquid bag 4, so that the stability of the liquid bag 4 in an inclined state can be improved, and the liquid bag 4 and the suction syringe 8 can be conveniently matched for pipetting.

In some examples, pipetting may be performed with the vial 3 at a predetermined angle to the vertical. In other words, pipetting can be performed with the vial 3 tilted. Specifically, the medicine bottle 3 may be moved to the first pipetting station, then the liquid bag handling mechanism 40 rotates to make the medicine bottle 3 in an inclined state, and then the suction injector 8 is moved to above the mouth of the medicine bottle 3, and moves downward to pierce the needle tube 84 into the body of the medicine bottle 3 to perform liquid suction. In this case, the manual pipetting operation can be simulated to the maximum extent, and the liquid medicine in the medicine bottle 3 can be sucked as much as possible, so that the residual liquid medicine can be reduced, and the utilization rate of the liquid medicine can be improved.

Fig. 33 is a schematic diagram illustrating a cabinet 700 according to an example of the present disclosure. Fig. 34 is a schematic diagram illustrating an external airflow through a cabinet 700 in accordance with examples of the present disclosure.

In some examples, referring to fig. 33, the dispensing device 2 may include a cabinet 700 having a receiving space. The cabinet 700 may provide support, protection, and sealing for the vial processing device 100, the fluid bag processing device 300, and the stopper processing device 500.

In some examples, referring to fig. 33, the cabinet 700 may include a perforated plate 720, and the perforated plate 720 may be understood as a flat plate having a plurality of through holes 722 (one of which 722 is schematically identified in fig. 33). Wherein the through holes 722 may have a preset aperture.

In some examples, the perforated plate 720 may be horizontally disposed, and the horizontally disposed perforated plate 720 may divide the receiving space of the cabinet 700 into an upper half and a lower half. In this case, the receiving space of the cabinet 700 can be divided into two relatively independent spaces; in addition, since the porous plate 720 has the plurality of through holes 722, gas can be circulated between the upper half and the lower half of the accommodating space.

In some examples, the vial processing device 100, the bag processing device 300, and the syringe processing device 500 may be located in the upper half of the containment space. In this case, the medicine bottle processing device 100, the liquid bag processing device 300 and the suction and injection device processing device 500 are located in the same space to be reasonably arranged, so that the three devices can be matched with each other to realize automatic liquid preparation. In addition, since the medicine bottle treating apparatus 100, the liquid bag treating apparatus 300, and the suction and injection device treating apparatus 500 are located at the relatively high upper half portion in the accommodating space, it is possible to preferably reduce the deposition of impurities such as dust or disinfectant residues on the surfaces of the three apparatuses.

(Airflow guiding mechanism 900)

With continued reference to fig. 33, the dispensing device 2 may further include an airflow directing mechanism 900. The air flow guiding mechanism 900 may be used to input clean air (e.g., clean air) into the accommodating space of the cabinet 700, and to purify and discharge exhaust gas in the accommodating space of the cabinet 700. This can improve the cleanliness of the liquid preparation environment. In some examples, the airflow directing mechanism 900 may also be referred to as a ventilation system.

In some examples, referring to fig. 34, the air flow guiding mechanism 900 may include an air inlet structure 920 and an air outlet structure 940, the air inlet structure 920 may input air into the receiving space of the cabinet 700, and the air outlet structure 940 may exhaust the exhaust gas in the receiving space of the cabinet 700. In this case, the air inlet structure 920 and the air outlet structure 940 cooperate to form an air circulation loop, so that air in the accommodating space of the cabinet 700 can circulate. In some examples, the exhaust gas may represent a gas doped with dust, water vapor, residual disinfectant, and other suspended impurities.

In some examples, the air intake structure 920 may be located at the top of the cabinet 700 and the air intake structure 920 may communicate with an upper half of the receiving space (see fig. 33). In this case, the air output through the air intake structure 920 can be made to directly enter the upper half of the accommodating space, thereby improving the purifying efficiency of purifying the upper half of the accommodating space.

With continued reference to fig. 34, in some examples, the air intake structure 920 may include a first filter layer 924 and an plenum 922. The plenum 922 and the first filter layer 924 may cooperate to provide the inlet structure 920 with a clean gas output.

In some examples, the first filter layer 924 may be used to purge gas, i.e., the first filter layer 924 may filter and purge gas passing through the first filter layer 924 to obtain clean gas. For example, the first filter layer 924 may be used to filter, for example, bacteria, dust, water vapor, and other suspended impurities in the air to obtain clean air.

In some examples, plenum 922 may provide a source of gas for gas inlet structure 920. Specifically, the air supply part 922 may include a first air inlet end and a first air outlet end, and the air supply part 922 may obtain external air through the first air inlet end and output the air through the first air outlet end. In this case, the gas supply portion 922 supplies a gas source to the gas inlet structure 920, so that the gas inlet structure 920 can continuously output clean gas.

In some examples, referring to fig. 34, the air intake structure 920 may include an air plenum 922 and a first filter layer 924 disposed in sequence along a direction G of air flow through the air intake structure 920. In this case, the outside air (for example, air) can be output through the air supply portion 922 and then reach the first filter layer 924, and the air can be filtered and purified through the first filter layer 924, so that the clean air can be output from the air intake structure 920.

In some examples, the air outlet structure 940 may be in communication with a lower half of the accommodation space (see fig. 33). Specifically, the air outlet structure 940 may be provided at the lower half of the cabinet 700 and may communicate with the lower half of the receiving space. In other words, the air outlet structure 940 may be disposed at a position lower than the air inlet structure 920 in the cabinet 700. In this case, since the air inlet structure 920 is disposed at a position higher than the air outlet structure 940, when the accommodating space of the cabinet 700 is sprayed with the sterilizing agent such as sterilizing alcohol, the efficiency of discharging the sterilizing agent remaining in the air out of the accommodating space can be improved by the air flow flowing from the top down.

In some examples, the air out structure 940 may have a second filter layer 942 and an air bleed 944. The air extraction portion 944 and the second filter layer 942 may cooperate to enable the air outlet structure 940 to extract air from the accommodating space of the cabinet 700 and purify the extracted air to be discharged out of the cabinet 700.

In some examples, the second filter layer 942 may be used to purify the exhaust gas, i.e., the second filter layer 942 may filter and purify the exhaust gas passing through the second filter layer 942 to obtain a cleaner gas. For example, the second filter layer 942 may be used to filter bacteria, dust, residual sanitizing agents, and other suspended impurities in the exhaust gas, for example, to obtain a relatively clean gas.

In some examples, the suction portion 944 may include a second air inlet end and a second air outlet end, and the suction portion 944 may capture gas within the receiving space of the cabinet 700 through the second air inlet end and exhaust gas through the second air outlet end. Thereby, the exhaust gas in the accommodation space of the cabinet 700 can be continuously discharged from the gas outlet structure 940.

In some examples, referring to fig. 34, the air exit structure 940 may include an air extraction 944 and a second filter 942 disposed in sequence along the direction G of the air flow through the air exit structure 940. In this case, the gas (for example, exhaust gas) in the accommodation space of the cabinet 700 can be outputted through the air suction portion 944 and then reaches the second filter layer 942, and the exhaust gas can be filtered and purified through the second filter layer 942, so that the relatively clean gas can be discharged from the air discharge structure 940.

In the air flow guiding mechanism 900 according to the present disclosure, through the air inlet structure 920 and the air outlet structure 940, an air flow circulation loop can be formed in the accommodating space of the cabinet 700, so that the air in the accommodating space flows, and thus clean air flow can be input into the accommodating space and the air (for example, exhaust gas) in the accommodating space can be discharged, thereby improving the cleanliness in the accommodating space of the cabinet 700, that is, improving the cleanliness of the liquid dispensing environment. In addition, since the air inlet structure 920 is disposed at a position higher than the air outlet structure 940, when the sterilizing agent such as sterilizing alcohol is sprayed into the accommodating space of the cabinet 700, the efficiency of discharging the sterilizing agent remaining in the air out of the accommodating space of the cabinet 700 can be improved by the air flow flowing from the top down.

Fig. 35 is a schematic diagram illustrating a dosing platform 6 according to an example of the present disclosure. Fig. 36 is a schematic diagram illustrating an operating platform 60 and a magazine 12 according to examples of the present disclosure. Fig. 37 is a block diagram showing the structure of the dosing platform 6 according to the example of the present disclosure.

As described above, the dispensing system 1 further includes a dosing platform 6, and the dosing platform 6 may dose the dispensing device 2 to enable the dispensing device 2 to automatically dispense the drug and the solution. Specifically, according to the requirement of the liquid preparation, the medicine bottles 3 may be loaded in batches to the medicine boxes 12 through the medicine loading platform 6, and then the medicine boxes 12 loaded with the medicine bottles 3 are assembled to the frame 11 of the medicine bottle loading mechanism 10. Thereby completing the dosing of the liquid dispensing device 2.

In some examples, the dosing platform 6 may be used to provide an environment for loading the vials 3 for the magazine 12. Specifically, the medicine box 12 may be recorded with medicine box information, the medicine bottle 3 may be recorded with medicine bottle information, the medicine bottle information of the preloaded medicine bottle 3 may be compared with the medicine box information before the medicine box 12 is loaded with the medicine bottle 3, the medicine bottle 3 is loaded into the medicine box 12 according to the comparison result, and after the operation of loading the medicine bottle 3 into the medicine box 12 is completed, the medicine box 12 loaded with the medicine bottle 3 may be assembled on the frame body. In this case, before loading the medicine bottles 3 into the medicine boxes 12, by comparing the medicine bottle information of the preloaded medicine bottles 3 with the medicine box information, it is possible to obtain a comparison result of whether the preloaded medicine bottles 3 fit the current medicine boxes 12, so that an operator can be instructed to load the medicine bottles 3 into the medicine boxes 12 according to the comparison result, and thus the dosing accuracy of the liquid dispensing system can be improved.

In some examples, the cartridge 12 may have an electronic label thereon that records the cartridge information, and the vial 3 may have a barcode that records the vial information. In other examples, a bar code describing the vial information may also be located in the vial package.

In some examples, referring to fig. 35, the dosing platform 6 may include an operating platform 60, and the operating platform 60 may have a reader/writer 62. When the cartridge 12 is placed on the operating platform 60, the reader/writer 62 may read the electronic tag to obtain the cartridge information (see fig. 36). In this case, the reader-writer 62 can automatically read the electronic tag of the medicine box 12 in a radio frequency identification mode, and the radio frequency signal transmission speed is high, the transmission is stable, and the reading efficiency and the accuracy of the reading result can be improved; in addition, the radio frequency identification mode is less influenced by external environment factors (such as illumination or dust, etc.), so that the stability of the reading process can be improved. In some examples, the cartridge information may include information (also referred to as first information) for the cartridge 12, such as a serial number of the cartridge 12 and an adapted vial type.

In some examples, referring to fig. 35, the drug delivery platform 6 may include a scanner 64, and the scanner 64 may scan a barcode on the drug vial 3 (or drug vial package) to obtain drug vial information. Specifically, the scanner 64 may scan a barcode recorded with vial information to obtain vial information prior to loading the vial 3 into the magazine 12. Therefore, the medicine bottle information can be conveniently and accurately obtained. In some examples, the vial information may include information (also referred to as second information) such as a vial type and a loaded drug for the vial 3.

In some examples, referring to fig. 37, the drug delivery platform 6 may include a control center 66, and the control center 66 may be configured to receive the first information and the second information and perform, for example, an analytical peer-to-peer process on the first information and the second information.

In some examples, the control center 66 may be communicatively coupled to the reader/writer 62 and the scanner 64. Thereby, the control center 66 can be made to directly obtain the first information and the second information. In some examples, the reader 62 may be in wired communication with the control center 66, and the scanner 64 may be in wired communication with the control center 66. However, the present disclosure is not limited thereto, and in other examples, the reader/writer 62 and the control center 66 may be connected by wireless communication, and the scanner 64 and the control center 66 may also be connected by wireless communication.

In some examples, the reader/writer 62 may transmit the cartridge information to the control center 66. Specifically, after the reader/writer 62 completes reading the electronic tag, the reader/writer 62 may transmit the cartridge information to the control center 66 by way of wired or wireless communication. Thereby, the timeliness of the control center 66 acquiring the first information can be improved.

In some examples, scanner 64 may transmit vial information to control center 66. Specifically, after the scanner 64 scans the barcode with the vial information recorded therein, the scanner 64 may transmit the vial information to the control center 66 by means of wired or wireless communication. Thereby, the timeliness of the control center 66 acquiring the second information can be improved.

In some examples, control center 66 may analytically compare the vial information to the cartridge information. Specifically, the control center 66 may acquire the comparison result of whether the preloaded vial 3 is adapted to the current magazine 12 by comparing the first information and the second information; in addition, the control center 66 may obtain the result of the association of what medicament is currently loaded in the magazine 12 by associating the first information with the second information.

In some examples, after the control center 66 obtains the second information, recorded data may be formed from which information of the drug to be added to the liquid dispensing system 1 may be recorded. Therefore, the method can facilitate backtracking and source-tracing of the dosing process.

In some examples, referring to fig. 37, the control center 66 may have a display screen 68, and the display screen 68 may be used to display the alignment results. In some examples, the display screen 68 may be used to display the comparison results and the association results. In this case, the operator can be instructed to load the vial 3 into the magazine 12 according to the result of the comparison, and confirm whether or not the medicine currently loaded in the magazine 12 is correct according to the result of the correlation, whereby the dosing accuracy of the liquid dispensing system can be improved.

In the drug delivery platform 6 according to the present disclosure, when the drug cassette 12 is placed on the operation platform 60, the reader/writer 62 can acquire the drug cassette information by reading the electronic tag on the drug cassette 12 and transmit the drug cassette information to the control center 66, so that the control center 66 can acquire the first information such as the serial number and the adapted drug bottle type for the drug cassette 12; when loading the vial 3 into the magazine 12, the scanner 64 scans the barcode of the vial 3 and transmits the vial information to the control center 66 so that the control center 66 can acquire second information, such as the vial type and the loaded drug, for the vial 3. In this case, on the one hand, the control center 66 can acquire whether the preloaded vial 3 is adapted to the comparison result of the current magazine 12 by comparing the first information and the second information, and display the comparison result on the display screen 68; on the other hand, the control center 66 can acquire the association result of what kind of medicine is loaded in the current magazine 12 by associating the first information with the second information, and display the association result on the display screen 68; therefore, an operator can be guided to load the medicine bottle 3 into the medicine box 12 according to the comparison result, and whether the medicine loaded in the current medicine box 12 is correct or not can be confirmed according to the association result, so that the medicine adding accuracy of the liquid distribution system can be improved. In addition, the second information is acquired by the control center 66, so that the information of the medicine added to the liquid distribution system 1 can be recorded conveniently, and the retrospective source-following of the medicine adding process is facilitated.

Fig. 38 is a schematic diagram illustrating a first monitoring mechanism 810 disposed on a cabinet 700 according to an example of the present disclosure.

In some examples, the liquid dispensing system 1 may further comprise a monitoring device. The monitoring device can monitor and record the whole process of the liquid preparation device 2 and the process of loading the medicine bottles 3 on the medicine adding platform 6.

In some examples, the monitoring device may include a first monitoring mechanism 810, and the first monitoring mechanism 810 may be used to monitor the dispensing process. In some examples, monitoring the dispensing process may mean video of the dispensing process and storing video data.

In some examples, the first monitoring mechanism 810 may be provided to the liquid dispensing device 2. Specifically, the first monitoring mechanism 810 may include a plurality of cameras, which may be respectively disposed at corresponding positions in the cabinet 700 according to the monitoring requirements (see fig. 38). For example, the first camera 811 may be positioned to facilitate viewing the location of the first pipetting station to monitor the process of the pipettor 8 automatically aspirating the medication within the vials 3 (fig. 38 schematically illustrates the location of the first camera 811 within the cabinet 700). For another example, the second camera 812 may be positioned to facilitate viewing of the second pipetting station to monitor the process of the pipettor 8 automatically infusing medication into the fluid bag 4 (fig. 38 schematically illustrates the position of the second camera 812 within the cabinet 700). The present disclosure is not limited thereto, and in other examples, a process in which the inhaler 8 automatically aspirates the medicine in the medicine bottle 3 and a process in which the inhaler 8 automatically injects the medicine into the liquid bag 4 may be monitored using one camera.

In some examples, a camera may be utilized to monitor the process of picking up the vial 3 and uncapping the vial 3 by the vial handling mechanism 20. In some examples, the camera may be used to monitor the process of picking up the fluid bag 4 and inverting the fluid bag 4 by the fluid bag handling mechanism 40.

In some examples, monitoring the dispensing process by the first monitoring mechanism 810 may feed back various alarm information that occurs during the dispensing process. For example, monitoring each link of the liquid preparation process by using a plurality of cameras can feed back various alarm information such as failure to pick up the medicine bottle 3, failure to remove the cap of the medicine bottle 3, failure to pick up the liquid bag 4, and failure to pick up the suction syringe 8.

The first monitoring mechanism 810 according to the present disclosure monitors each link of the automatic liquid dispensing process by using a plurality of cameras disposed in the cabinet 700, so that the liquid dispensing process of the liquid dispensing device 2 can be monitored in an omnibearing manner, and thus an operator can conveniently know the situation of liquid dispensing in real time; in addition, the whole process of the liquid preparation process can be recorded by recording the liquid preparation process and storing video data, so that the follow-up tracing and source tracking are facilitated; in addition, the alarm information fed back by the first monitoring mechanism 810 can enable an operator to timely process errors occurring in the liquid preparation process.

In some examples, the monitoring device may include a second monitoring mechanism 820. The second monitoring mechanism 820 may be used to monitor the process of loading the vials 3.

In some examples, the second monitoring mechanism 820 may be provided to the dosing platform 6 (see fig. 35). Specifically, the second monitoring mechanism 820 may include at least one camera (also referred to as a third camera 822), and the third camera 822 may be disposed at a position corresponding to the dosing platform 6 according to the requirement for monitoring (fig. 35 schematically illustrates that the third camera 822 is disposed at the position of the dosing platform 6). For example, the third camera 822 may be disposed above the operator platform 60.

In some examples, the second monitoring mechanism 820 may include two cameras that may be respectively positioned to facilitate viewing the operating platform 60 such that the imaging range of the two cameras covers the operating platform 60. In this case, the process of loading the medicine bottle 3 on the medicine loading platform 6 by the operator can be monitored in an omnibearing manner, so that the whole process of the medicine loading process can be recorded (for example, video recording is performed, video recording data are stored, etc.), and the follow-up tracing of the medicine loading process is facilitated.

While the disclosure has been described in detail in connection with the drawings and examples, it is to be understood that the foregoing description is not intended to limit the disclosure in any way. Modifications and variations of the present disclosure may be made as desired by those skilled in the art without departing from the true spirit and scope of the disclosure, and such modifications and variations fall within the scope of the disclosure.

Claims

1. A liquid preparation system is characterized in that,

The liquid dispensing system comprises a liquid dispensing device and a medicine adding platform, wherein the liquid dispensing device comprises a medicine bottle processing device, a liquid bag processing device and a suction and injection device processing device, the medicine bottle processing device, the liquid bag processing device and the suction and injection device processing device are matched to transfer liquid between a medicine bottle and a liquid bag through a suction and injection device, the medicine bottle processing device comprises a medicine bottle carrying mechanism for carrying the medicine bottle and a medicine bottle carrying mechanism for carrying the medicine bottle, and the medicine bottle carrying mechanism comprises a frame body and a medicine box which is provided with a medicine bottle bin for accommodating the medicine bottle and is detachably assembled on the frame body; the medicine loading platform is used for providing an environment for loading the medicine bottles for the medicine boxes, medicine box information is recorded on the medicine boxes, before the medicine boxes are loaded with the medicine bottles, medicine bottle information of the medicine bottles preloaded is compared with the medicine box information, and after the medicine boxes are loaded with the medicine bottles, the medicine boxes loaded with the medicine bottles are assembled on the frame body.

2. The fluid dispensing system of claim 1 wherein,

The liquid dispensing device also comprises a cabinet body with an accommodating space and an air flow guiding mechanism,

The cabinet body comprises a porous plate which is horizontally arranged, the porous plate divides the accommodating space of the cabinet body into an upper half part and a lower half part, the medicine bottle processing device, the liquid bag processing device and the suction injector processing device are positioned at the upper half part of the accommodating space,

The air flow guiding mechanism comprises an air inlet structure and an air outlet structure, the air inlet structure comprises a first filter layer and an air supply part, the air inlet structure is positioned at the top of the cabinet body and is communicated with the upper half part of the accommodating space, the air outlet structure is provided with a second filter layer and an air exhaust part, and the air outlet structure is communicated with the lower half part of the accommodating space.

3. The fluid dispensing system of claim 1 wherein,

The liquid preparation system further comprises a monitoring device, wherein the monitoring device comprises a first monitoring mechanism used for monitoring the liquid preparation process and arranged in the liquid preparation device, and a second monitoring mechanism used for monitoring the medicine bottle loading process and arranged in the medicine adding platform.

4. The fluid dispensing system of claim 1 wherein,

The medicine adding platform comprises an operation platform with a reader-writer, a scanner and a control center with a display screen and in communication connection with the reader-writer and the scanner, wherein an electronic tag for recording medicine box information is arranged on the medicine box, when the medicine box is arranged on the operation platform, the reader-writer reads the electronic tag to acquire the medicine box information and transmits the medicine box information to the control center, and before the medicine box is loaded with medicine bottles, the scanner scans bar codes for recording medicine bottle information of preloaded medicine bottles to acquire the medicine bottle information and transmits the medicine bottle information to the control center, and the control center compares the medicine bottle information with the medicine box information and displays a comparison result on the display screen.

5. The fluid dispensing system of claim 1 wherein,

The liquid bag processing device comprises a liquid bag carrying mechanism for carrying the liquid bag and a movable liquid bag carrying mechanism for carrying the liquid bag;

the suction and injection device processing device comprises a suction and injection device carrying mechanism for carrying the suction and injection device, a movable suction and injection device carrying mechanism for carrying the suction and injection device, and a liquid transferring mechanism arranged on the suction and injection device carrying mechanism;

the liquid dispensing device is provided with a first liquid transferring station and a second liquid transferring station, the first liquid transferring station is a region where the moving track of the medicine bottle carrying mechanism and the moving track of the suction and injection device carrying mechanism can be overlapped, the second liquid transferring station is a region where the moving track of the liquid bag carrying mechanism and the moving track of the suction and injection device carrying mechanism can be overlapped,

When liquid is prepared, the medicine bottle carrying mechanism moves the medicine bottle to the first liquid transferring station, the liquid bag carrying mechanism moves the liquid bag to the second liquid transferring station, the suction and injection device carrying mechanism moves the suction and injection device between the first liquid transferring station and the second liquid transferring station, and the liquid transferring mechanism controls the suction and injection device to transfer liquid between the medicine bottle and the liquid bag.

6. The fluid dispensing system of claim 1 wherein,

The medicine bottle loading mechanism comprises a blocking part which is arranged at one end of the medicine box and can be opened and closed at the bin opening of the medicine bottle bin, and a pushing part which is movably arranged on the medicine box and can apply pushing action to medicine bottles in the medicine bottle bin along the direction from the bin tail of the medicine bottle bin to the bin opening of the medicine bottle bin,

The medicine bottle carrying mechanism is provided with a medicine bottle clamping part which can clamp the medicine bottle in a releasing way, a movable first base and a touching part which is matched with the blocking part to open the bin opening of the medicine bottle bin, the medicine bottle clamping part is arranged on the first base,

The touch part comprises a mounting component, a touch component and a detection component, wherein the touch component and the detection component are arranged on the mounting component, the touch component is movably arranged on the mounting component and is provided with a preset detection area corresponding to the position of the blocking part when the bin opening of the medicine bottle bin is opened, when the touch part applies an action to the blocking part, the touch component is abutted against the blocking part and moves relative to the detection component,

The detection member has a detection area, and when the mouth of the medicine bottle bin is opened, a preset detection area of the touch member at least partially overlaps with the detection area of the detection member.

7. The fluid dispensing system of claim 5 wherein,

The liquid bag carrying mechanism comprises a movable base, a supporting seat, a liquid bag clamping part and a sucker, wherein the supporting seat is arranged on the base in a mode of rotating around a rotating shaft, the liquid bag clamping part is arranged on the supporting seat, when liquid is prepared, the liquid bag carrying mechanism clamps the liquid bag to move to the second liquid transferring station, the liquid bag is enabled to form a preset angle with the rotating shaft, and the sucker adsorbs the liquid bag when the liquid bag forms a preset angle with the rotating shaft.

8. The fluid dispensing system of claim 5 wherein,

The suction and injection device processing device further comprises a calibration mechanism which is provided with a calibration area and is used for calibrating the position of the suction and injection device, when liquid is prepared, the suction and injection device carrying mechanism firstly moves the suction and injection device to the calibration area, the calibration mechanism calibrates the needle tube position of the suction and injection device to obtain the calibration coordinate value of the needle tube, and the suction and injection device carrying mechanism plans a moving route based on the calibration coordinate value so that the suction and injection device moves between the first pipetting station and the second pipetting station.

9. The fluid dispensing system of claim 1 wherein,

The medicine bottle is an ampoule bottle and comprises a main body part, a bottle cap and a bottle neck connecting the main body part and the bottle cap,

The medicine bottle treatment device comprises an ampoule bottle cap removing mechanism,

The ampoule bottle cap removing mechanism comprises a cutting mechanism for cutting the bottle neck and a bottle knocking mechanism,

The scribing mechanism comprises a rotating part with a cutter wheel, the bottle knocking mechanism is provided with a first base and a thin rod rotatably arranged on the first base,

The ampoule bottle cap removing mechanism is provided with a bottle cutting station and a bottle knocking station, the ampoule bottle conveying mechanism conveys a medicine bottle to the bottle cutting station, the cutter wheel rotates and cuts the bottle neck, the ampoule bottle conveying mechanism conveys the cut medicine bottle to the bottle knocking station, and the thin rod rotates and knocks the bottle cap to separate the bottle cap from the bottle neck.

10. The fluid dispensing system of claim 1 wherein,

The medicine bottle is a penicillin bottle and comprises a bottle body with a containing cavity, a bottle neck with a hollow channel communicated with the containing cavity and a bottle cap arranged at the opening of the bottle neck, wherein the minimum width of the bottle cap is larger than the width of the joint of the bottle neck and the bottle cap,

The medicine bottle treatment device comprises a penicillin bottle cap removing mechanism,

The penicillin bottle cap removing mechanism comprises a separating mechanism and a shell covered outside the separating mechanism,

The separating mechanism comprises a second base, a clamping plate and an elastic component which are arranged on the second base,

The clamping plate is plate-shaped and extends towards the periphery of the second base, and is provided with a rear end relatively close to the second base and a front end opposite to the rear end, the clamping plate is arranged on the second base along the extending direction of the clamping plate in a telescopic way through the elastic component,

When the cap of the penicillin bottle is removed, the medicine bottle carrying mechanism carries the medicine bottle so that the lower surface of the bottle cap is abutted against the upper surface of the front end of the clamping plate, and the bottle body of the penicillin bottle moves away from the bottle cap to separate the bottle cap from the bottle neck.