CN118265724A - 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途 - Google Patents

肌肉靶向复合物及其用于治疗强直性肌营养不良的用途 Download PDF

Info

Publication number
CN118265724A
CN118265724A CN202280060779.9A CN202280060779A CN118265724A CN 118265724 A CN118265724 A CN 118265724A CN 202280060779 A CN202280060779 A CN 202280060779A CN 118265724 A CN118265724 A CN 118265724A
Authority
CN
China
Prior art keywords
xdc
seq
xoc
oligonucleotide
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280060779.9A
Other languages
English (en)
Chinese (zh)
Inventor
斯特凡诺·扎诺蒂
泰勒·皮卡里洛
蒂莫西·威登
科迪·A·德雅尔丹
罗梅什·R·苏布拉马尼亚
穆罕默德·T·卡塔纳尼
布伦丹·奎因
约翰·纳吉姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyne Therapeutics Inc
Original Assignee
Dyne Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyne Therapeutics Inc filed Critical Dyne Therapeutics Inc
Priority claimed from PCT/US2022/073536 external-priority patent/WO2023283620A1/en
Publication of CN118265724A publication Critical patent/CN118265724A/zh
Pending legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CN202280060779.9A 2021-07-09 2022-07-08 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途 Pending CN118265724A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63/220,000 2021-07-09
US202263316905P 2022-03-04 2022-03-04
US63/316,905 2022-03-04
PCT/US2022/073536 WO2023283620A1 (en) 2021-07-09 2022-07-08 Muscle targeting complexes and uses thereof for treating myotonic dystrophy

Publications (1)

Publication Number Publication Date
CN118265724A true CN118265724A (zh) 2024-06-28

Family

ID=91603709

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280060779.9A Pending CN118265724A (zh) 2021-07-09 2022-07-08 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途

Country Status (2)

Country Link
JP (1) JP2024532964A (https=)
CN (1) CN118265724A (https=)

Also Published As

Publication number Publication date
JP2024532964A (ja) 2024-09-11

Similar Documents

Publication Publication Date Title
JP7804685B2 (ja) 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用
CN115349013B (zh) 肌肉靶向复合物及其用于治疗面肩肱型肌营养不良的用途
US11844843B2 (en) Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US20240325558A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11633498B2 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20240016952A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20230272065A1 (en) Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
CN115427108A (zh) 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途
JP2024524222A (ja) 筋標的化複合体およびフリードライヒ運動失調症を処置するためのその使用
CN115335401A (zh) 肌肉靶向复合物及其用于治疗肌养蛋白病的用途
US12102687B2 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
JP2024527362A (ja) 筋標的化複合体およびジストロフィノパチーを処置するためのその使用
CN118401553A (zh) 肌肉靶向复合物及其用于治疗肌养蛋白病的用途
JP2024525610A (ja) 筋標的化複合体およびジストロフィノパチーを処置するためのその使用
JP2021533199A (ja) 筋強直症ジストロフィーを処置するための筋標的化複合体およびそれらの使用
CN118662653A (zh) 肌肉靶向复合物及其用于治疗蓬佩病的用途
JP2024546436A (ja) 顔面肩甲上腕筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用
WO2021142269A1 (en) Muscle targeting complexes and uses thereof for modulation of genes associated with muscle atrophy
JP2025522875A (ja) 顔面肩甲上腕型筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用
CN118265724A (zh) 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途
CN118251240A (zh) 用于治疗面肩肱型肌营养不良的肌肉靶向复合物
CN118450896A (zh) 肌肉靶向复合物及其用于治疗肌养蛋白病的用途
CN116940680A (zh) 肌肉靶向复合物及其用于治疗强直性肌营养不良的用途

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination