CN118202097A - 分子条形码以及相关方法和系统 - Google Patents

分子条形码以及相关方法和系统 Download PDF

Info

Publication number
CN118202097A
CN118202097A CN202280029417.3A CN202280029417A CN118202097A CN 118202097 A CN118202097 A CN 118202097A CN 202280029417 A CN202280029417 A CN 202280029417A CN 118202097 A CN118202097 A CN 118202097A
Authority
CN
China
Prior art keywords
marker
beads
cleavage
identifier
molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280029417.3A
Other languages
English (en)
Chinese (zh)
Inventor
C·M·丹巴赫尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon Health & Science University
Original Assignee
Oregon Health & Science University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon Health & Science University filed Critical Oregon Health & Science University
Publication of CN118202097A publication Critical patent/CN118202097A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
CN202280029417.3A 2021-03-04 2022-03-04 分子条形码以及相关方法和系统 Pending CN118202097A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163156858P 2021-03-04 2021-03-04
US63/156,858 2021-03-04
PCT/US2022/019045 WO2022187719A1 (en) 2021-03-04 2022-03-04 Molecular barcodes and related methods and systems

Publications (1)

Publication Number Publication Date
CN118202097A true CN118202097A (zh) 2024-06-14

Family

ID=83154643

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280029417.3A Pending CN118202097A (zh) 2021-03-04 2022-03-04 分子条形码以及相关方法和系统

Country Status (8)

Country Link
US (1) US20240158784A1 (cg-RX-API-DMAC7.html)
EP (1) EP4301909A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024509822A (cg-RX-API-DMAC7.html)
KR (1) KR20230165231A (cg-RX-API-DMAC7.html)
CN (1) CN118202097A (cg-RX-API-DMAC7.html)
AU (1) AU2022230449A1 (cg-RX-API-DMAC7.html)
CA (1) CA3209941A1 (cg-RX-API-DMAC7.html)
WO (1) WO2022187719A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2026508331A (ja) * 2023-02-28 2026-03-10 オレゴン ヘルス アンド サイエンス ユニバーシティ 分子バーコーディングのための組成物および方法
EP4689182A1 (en) * 2023-03-28 2026-02-11 Oregon Health & Science University Orthogonal cleavage ligation sequencing (ocls)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
WO2016138496A1 (en) * 2015-02-27 2016-09-01 Cellular Research, Inc. Spatially addressable molecular barcoding
CN110249050B (zh) * 2016-11-08 2023-08-18 南纳治疗有限公司 无标签编码化合物文库
KR20210104030A (ko) * 2018-12-14 2021-08-24 얼티뷰, 인크. 표적을 순차적으로 검출하는 방법 및 조성물

Also Published As

Publication number Publication date
EP4301909A1 (en) 2024-01-10
US20240158784A1 (en) 2024-05-16
JP2024509822A (ja) 2024-03-05
CA3209941A1 (en) 2022-09-09
WO2022187719A1 (en) 2022-09-09
EP4301909A4 (en) 2025-02-26
AU2022230449A1 (en) 2023-09-07
KR20230165231A (ko) 2023-12-05
WO2022187719A9 (en) 2024-04-11
AU2022230449A2 (en) 2023-09-28

Similar Documents

Publication Publication Date Title
KR102091207B1 (ko) Ｄｎａ―코딩된 라이브러리의 생성 및 스크리닝 방법
JP7097627B2 (ja) 核酸エンコーディングを使用した巨大分子解析
JP7390027B2 (ja) 核酸エンコーディングおよび／または標識を使用する解析のためのキット
AU2023210577A1 (en) Hybridization chain reaction methods for in situ molecular detection
US20240158784A1 (en) Molecular barcodes and related methods and systems
JP2024509822A5 (cg-RX-API-DMAC7.html)
AU2023384167A1 (en) Chromatin profiling compositions and methods
AU2024229387A1 (en) Compositions and methods for molecular barcoding
EP4139473A1 (en) Methods and compositions for making and using peptide arrays
HK40101324A (en) Methods for screening aptamers using sequencing
CN121127608A (zh) 正交切割连接测序(ocls)
HK1253711B (en) Methods of creating and screening dna-encoded libraries

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination