CN1181864C - Pain eliminating liquor No.1 - Google Patents

Abstract

The present invention relates to an externally applied Chinese materia medica preparation for treating cervical spondylosis, namely a No. 1 pain alleviating liquid which relates to the technical field of medicines. One dosage of the present invention is prepared from 0.8 to 1.0 gram of cortex cereis, 0.4 to 0.7 gram of safflower, 0.4 to 0.7 gram of twotoothed achyranthes root, 0.6 to 0.9 gram of girald daphne bark, 0.4 to 0.7 gram of giant knotweed rhizome, 0.5 to 0.8 gram of yam, 0.3 to 0.6 gram of phellodendron bark, 0.3 to 0.6 gram of rhubarb, 0.4 to 0.7 gram of paniculate swallowwort root, 0.4 to 0.7 gram of atractylodes rhizome, 0.3 to 0.6 gram of Chinese angelica, 0.4 to 0.7 gram of jackinthepulpit tuber and 0.4 to 0.7 gram of licorice root. The present invention has the preparation method that the medicines are taken according to the weight percentage and dried into coarse powder, the coarse powder is sterilized and immersed in alcohol, and liquid medicine is filtered out and packaged. The present invention adopts an optimized prescription composed of various traditional Chinese medicines; the present invention is an externally applied preparation which has the effects of relieving inflammation, alleviating pain and improving functions; the present invention has convenient use, simple preparation process and low cost; clinical therapy shows that the qualification rate is 95.85%, the total effective rate is 98.52%, the shortest treatment time is 10 days, the longest treatment time is 68 days, the curative effect is strengthened, and the relapse rate is low.

Description

A kind of external medicinal liquid for the treatment of cervical vertebra pain and preparation method thereof

Technical field the present invention is a field of pharmaceutical technology, relates to a kind of external medicinal liquid for the treatment of cervical vertebra pain and preparation method thereof.

The background technology cervical spondylosis is common ailment of middle-aged and old, frequently-occurring disease.Main pathogenesis is that the degenerative change of intervertebral disc and accessory structure thereof causes symptoms such as neck-shoulder pain, limitation of activity, upper limb fiber crops pain to the compressing of nerve root and spinal cord and blood vessel.With advancing age, sickness rate rises year by year, has become the disease of a kind of people of influence orthobiosis, work.At present, the method for treatment cervical spondylosis is more, mainly contains naturopathy, manipulation and Drug therapy.Naturopathy and manipulation need the time longer, and the patient can not accept sometimes.The side effect of Drug therapy oral drugs is bigger, and it is slow to take effect.The traditional Chinese medical science claims that cervical spondylosis is a syndrome of blood stasis, Paralysis card category, is the result of human body the four stages in the course of an epidemic febrile disease, the imbalance of internal organs meridian function.According to different pathogenesis, main symptom and the characteristics of cervical spondylosis, the traditional Chinese medical science is divided into six types to cervical spondylosis: i.e. stagnate type, Paralysis pattern of syndrome, type of QI-stagnation and blood stasis, expectorant stasis of blood interlocking type, QIXUELIANGXU type and deficiency of the liver and kindey type of Taiyang channel governor vessel.Chinese medicine is in the difference of methods such as determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, prescription, dosage form, processing technique, and curative effect is widely different.

Summary of the invention the objective of the invention is to provide a kind of external medicinal liquid for the treatment of cervical vertebra pain and preparation method thereof for overcoming the above-mentioned treatment more effective treatment cervical spondylosis of lacking.

A kind of external medicinal liquid for the treatment of cervical vertebra pain of the present invention and preparation method thereof content Description:

A kind of external medicinal liquid for the treatment of cervical vertebra pain of the present invention is characterized in that: it is that following raw materials according infusion in ethanol by unit dose forms: Cortex cercis chinensis 0.8～1.0g, Flos Carthami 0.4～0.7g, Radix Achyranthis Bidentatae 0.4～0.7g, Daphne giraldii Nitsche 0.6～0.9g, Rhizoma Polygoni Cuspidati 0.4～0.7g, Rhizoma Dioscoreae Nipponicae 0.5～0.8g, Cortex Phellodendri 0.3～0.6g, Radix Et Rhizoma Rhei 0.3～0.6g, Radix Cynanchi Paniculati 0.4～0.7g, Rhizoma Atractylodis 0.4～0.7g, Radix Angelicae Sinensis 0.3～0.6g, Rhizoma Arisaematis 0.4～0.7g, Radix Glycyrrhizae 0.4～0.7g.

The preparation method of external medicinal liquid of treatment cervical vertebra pain, it is that bent the following step is made: take by weighing the said medicine prescription by weight ratio, dry coarse powder, sterilization, with alcohol-pickled, leach medicinal liquid, encapsulation.

Pain-relieving liquid of the present invention adopts plurality of Chinese to optimize prescription, has anti-inflammatory analgetic, improves the effect of function, makes external preparation, easy to use, preparation technology is simple, with low cost.Pain-relieving liquid clinical drug trial of the present invention is finished, and 2100 routine cervical spondylosis patients have been carried out the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs clinical practice of traditional Chinese medical science typing, and wherein the course of disease is the longest 18 years, 3 the shortest weeks; Taiyang channel governor vessel stagnate type 470 Li, Paralysis pattern of syndrome 1232 examples, type of QI-stagnation and blood stasis 202 examples, expectorant stasis of blood interlocking type 96 examples, QIXUELIANGXU type 58 examples, deficiency of the liver and kindey type 42 examples.Criterion of therapeutical effect:

Excellent: clinical symptoms and Signs complete obiteration, normal, the former work post work of recovery of function;

Very: symptom and Signs disappear substantially or part disappears;

Effectively: clinical symptoms and Signs are clearly better or improve;

Invalid: clinical symptoms and Signs do not have obvious improvement.

Pattern of syndrome	The example number	Excellent	Account for %	Very	Account for %	Effectively	Account for %	Invalid	Account for %
										The Taiyang channel type that stagnates	470	402	85.53	47	10	19	4.04	2	0.43
The Paralysis pattern of syndrome	1232	1196	97.08	30	2.44	4	0.32	2	0.16
										Type of QI-stagnation and blood stasis	202	176	87.13	18	8.91	5	2.48	3	1.49
Expectorant stasis of blood interlocking type	96	72	75	16	16.67	5	5.21	3	3.13
										QIXUELIANGXU type	58	22	37.93	12	20.69	12	20.96	12	20.69
The deficiency of the liver and kindey type	42	16	38.1	6	14.28	11	26.19	9	21.43
										Add up to	2100	1884	89.71	129	6.14	51	2.67	31	1.48

Through good 2013 examples of clinical treatment, acceptance rate 95.85%; Total effective 2069 examples, total effective rate is 98.52%.The shortest 10 days of treatment time, the longest 68 days, the efficacy consolidation relapse rate was lower, checked 1505 examples with examining after 6 months to 3 years, and 36 example recurrences are arranged, and the state of an illness is preceding light than treatment, and relapse rate is to follow up a case by regular visits to 2.39% of check case.

Specific embodiment embodiment 1

In sluggish myelopathy patient 470 examples of Tanggangzi Hospital's prescription on individual diagnosis treatment Taiyang channel governor vessel, the prescription of seance amount medication is: Cortex cercis chinensis 0.8g, Flos Carthami 0.6g, Radix Achyranthis Bidentatae 0.6g, Daphne giraldii Nitsche 0.8g, Rhizoma Polygoni Cuspidati 0.6g, Rhizoma Dioscoreae Nipponicae 0.7g, Cortex Phellodendri 0.3g, Radix Et Rhizoma Rhei 0.3g, Radix Cynanchi Paniculati 0.6g, Rhizoma Atractylodis 0.4g, Radix Angelicae Sinensis 0.5g, Rhizoma Arisaematis 0.4g, Radix Glycyrrhizae 0.6g in March, 2000～JIUYUE.The said medicine prescription got it filled after dry coarse powder, sterilization, with alcohol-pickled, leach medicinal liquid and make medicated cushion, after medicated cushion placed neck, heat with field effect therapeutic equipment, each 45 minutes, make medicine act on body by skin, get rid of evils and set upright, regulating blood circulation by heating power, smooth QI and blood reaches the purpose of curing the disease.Reach 99% through the treatment total effective rate.

Embodiment 2

Control treatment Paralysis pattern of syndrome cervical spondylosis patient 1232 examples in April calendar year 2001～JIUYUE at Anshan soup mound hospital admission, the prescription of seance amount medication is: Cortex cercis chinensis 0.7g, Flos Carthami 0.4g, Radix Achyranthis Bidentatae 0.4g, Daphne giraldii Nitsche 0.7g, Rhizoma Polygoni Cuspidati 0.4g, Rhizoma Dioscoreae Nipponicae 0.6g, Cortex Phellodendri 0.5g, Radix Et Rhizoma Rhei 0.5g, Radix Cynanchi Paniculati 0.4g, Rhizoma Atractylodis 0.4g, Radix Angelicae Sinensis 0.5g, Rhizoma Arisaematis 0.4g, Radix Glycyrrhizae 0.6g.The said medicine prescription got it filled after dry coarse powder, sterilization, with alcohol-pickled, leach medicinal liquid and make medicated cushion, after medicated cushion placed neck, heat with field effect therapeutic equipment, each 45 minutes, make medicine act on body by skin, get rid of evils and set upright, regulating blood circulation by heating power, smooth QI and blood reaches the purpose of curing the disease.Reach 99.8% through the treatment total effective rate.

Embodiment 3

Treat stagnation of QI and blood myelopathy patient 202 examples in April, 1999～August at Anshan soup mound hospital admission, the prescription of seance amount medication is: Cortex cercis chinensis 0.9g, Flos Carthami 0.5g, Radix Achyranthis Bidentatae 0.5g, Daphne giraldii Nitsche 0.9g, Rhizoma Polygoni Cuspidati 0.5g, Rhizoma Dioscoreae Nipponicae 0.7g, Cortex Phellodendri 0.4g, Radix Et Rhizoma Rhei 0.4g, Radix Cynanchi Paniculati 0.5g, Rhizoma Atractylodis 0.5g, Radix Angelicae Sinensis 0.4g, Rhizoma Arisaematis 0.5g, Radix Glycyrrhizae 0.5g.The said medicine prescription got it filled after dry coarse powder, sterilization, with alcohol-pickled, leach medicinal liquid and make medicated cushion, after medicated cushion placed neck, heat with field effect therapeutic equipment, each 45 minutes, make medicine act on body by skin, get rid of evils and set upright, regulating blood circulation by heating power, smooth QI and blood reaches the purpose of curing the disease.Reach 98.5% through the treatment total effective rate.

The effect of blood circulation promoting and blood stasis dispelling, dredging the meridian, anti-inflammatory analgetic is arranged according to pharmacological research proof Flos Carthami, Rhizoma Polygoni Cuspidati; Radix Cynanchi Paniculati, Daphne giraldii Nitsche, Rhizoma Atractylodis have expelling wind and removing dampness, analgesic effect.The present invention is the Therapeutic Principle with blood circulation promoting and blood stasis dispelling, dredging the meridian, improves function by easing the pain.

Claims (2)

1, a kind of external medicinal liquid for the treatment of cervical vertebra pain is characterized in that: it is that following raw materials according infusion in ethanol by unit dose forms: Cortex cercis chinensis 0.8～1.0g, Flos Carthami 0.4～0.7g, Radix Achyranthis Bidentatae 0.4～0.7g, Daphne giraldii Nitsche 0.6～0.9g, Rhizoma Polygoni Cuspidati 0.4～0.7g, Rhizoma Dioscoreae Nipponicae 0.5～0.8g, Cortex Phellodendri 0.3～0.6g, Radix Et Rhizoma Rhei 0.3～0.6g, Radix Cynanchi Paniculati 0.4～0.7g, Rhizoma Atractylodis 0.4～0.7g, Radix Angelicae Sinensis 0.3～0.6g, Rhizoma Arisaematis 0.4～0.7g, Radix Glycyrrhizae 0.4～0.7g.

2, a kind of preparation method of external medicinal liquid as claimed in claim 1 is characterized in that it is made by the following step: take by weighing the said medicine prescription by weight ratio, dry coarse powder, sterilization, with alcohol-pickled, leach medicinal liquid, encapsulation.