CN118079207A - Single balloon catheter with drug injection and blocking functions, device and operation method - Google Patents

Abstract

The application relates to a single balloon catheter with drug injection and blocking functions, equipment and an operation method, which are applied to the field of medical appliances. The balloon catheter comprises a first pipe fitting, a balloon and a second pipe fitting, wherein the first pipe fitting comprises a first through hole; the saccule is communicated with the first pipe fitting, and can stretch out and draw back along the radial direction to adapt to the lumen of the plugging esophagus; the second pipe fitting penetrates through the first pipe fitting, the second pipe fitting comprises a drug administration channel and a second through hole, and the second through hole can be communicated with the first through hole and the drug administration channel; in a closed state, the first through hole and the second through hole are not overlapped in the radial direction; in the working state, the first through hole and the second through hole are at least partially overlapped in the radial direction. After the single balloon catheter is inserted into the corresponding position, the balloon is inflated to realize the blocking of the lumen and the fixation of the catheter on the lesion part, so that hormone medicine can be fully mixed and soaked with the wound surface above the balloon, the perfusion effect can be maintained for a long time, and the clinical curative effect is further improved.

Description

Single balloon catheter with drug injection and blocking functions, device and operation method

Technical Field

The application relates to the technical field of medical instruments, in particular to a single balloon catheter with drug injection and blocking functions, equipment and an operation method.

Background

Submucosal dissection (Endoscopic submucosal dissection, ESD) via endoscope refers to endoscopic minimally invasive techniques that utilize various endoscopic electrotomes to submucosally dissect early lesions of the digestive tract greater than 2 cm. The technique realizes the whole excision of larger lesions and provides accurate pathological diagnosis stage for the lesions.

Compared with the traditional surgery, the ESD better maintains the physiological functions of the digestive tract on the basis of tumor resection, obviously improves the postoperative life quality of patients, and is currently the first choice treatment method for early cancers and precancerous lesions of the digestive tract including esophagus.

The common complications after large-area esophageal lesion ESD operation are lumen stenosis, which is also the current clinical pain point, and in order to solve the difficult problem, the current common method is as follows: methods such as hormone oral administration, hormone injection, expansion and stent are not exact in actual effect and inconsistent in repeatability.

Clinical researches show that the short-course oral administration of the hormone has better combined hormone soaking effect and can obviously reduce the incidence rate of esophageal lumen stenosis. In the process of intracavity hormone injection and soaking diagnosis and treatment, firstly, the gas in the gastric cavity and the esophageal cavity is required to be sucked out, and then the medicine diluent is injected into the esophageal cavity, but the retention time of the medicine in the lumen is uncontrollable due to the peristaltic movement of the lumen and the possible choking cough, so that the treatment effect is affected.

Disclosure of Invention

Based on the above, it is necessary to provide a single balloon catheter, a device and an operation method which have the functions of drug injection and blocking, aiming at the problem that the retention time of the drug in the lumen is uncontrollable in the hormone diagnosis and treatment process.

In a first aspect, the application provides a single balloon catheter with drug injection and blocking functions, which adopts the following technical scheme:

The single balloon catheter with the functions of drug injection and blocking comprises a first pipe fitting, a balloon and a second pipe fitting, wherein the first pipe fitting comprises a first through hole arranged on the side wall; the balloon is communicated with the first pipe fitting, the balloon is closer to the distal end of the first pipe fitting than the first through hole, and the balloon is configured to be capable of stretching along the radial direction, so that the balloon can be matched with a lumen of an esophagus; the second pipe fitting penetrates through the first pipe fitting, the second pipe fitting comprises a drug delivery channel for delivering drugs and a second through hole which is arranged on the side wall and communicated with the drug delivery channel, and the second through hole can be communicated with the first through hole and the drug delivery channel, so that the drugs are released to the outside; wherein, single sacculus pipe that has medicine injection concurrently, shutoff function includes closure state and operating condition: when in a closed state, the first through hole and the second through hole are not overlapped in the radial direction; when in a working state, the first through hole and the second through hole are at least partially overlapped in the radial direction.

In one embodiment, the single balloon catheter with the drug injection and blocking functions further comprises a limiting piece, wherein a limiting groove extending longitudinally is arranged in the first pipe fitting, and the limiting piece is connected to the outer wall of the second pipe fitting and is slidably mounted in the limiting groove.

In one embodiment, the limiting member comprises a closed position and a plurality of opening positions which are distributed at intervals with the closed position, the closed position is correspondingly arranged at the far end of the limiting groove, and all the opening positions are distributed at intervals from the far end of the limiting groove to the near end of the limiting groove; when the single balloon catheter with the drug injection and blocking functions is in a closed state, the limiting piece is switched to the closed position, so that the drug is blocked in the second pipe fitting; when the single balloon catheter with the drug injection and blocking functions is in a working state, the limiting piece can be switched to any opening position, and the first through hole is communicated with the second through hole, so that the drug is released.

In one embodiment, the single balloon catheter with the drug injection and blocking functions further comprises a plurality of opening ribs arranged in the limiting groove, wherein the opening ribs are arranged corresponding to the opening positions, and the opening ribs can be in contact with the limiting piece in the radial direction of the first pipe fitting.

In one embodiment, the balloon is provided with a filling cavity inside, the first pipe fitting further comprises a filling channel, the filling channel is communicated with the filling cavity and used for injecting filling medium into the filling cavity, and the balloon can stretch and retract along the longitudinal direction along with the change of the volume of the injected filling medium.

In one embodiment, the balloon is constructed of an elastic material, including silicone, rubber, and polyurethane materials.

In one embodiment, the single balloon catheter with the drug injection and blocking functions further comprises a plurality of marks arranged on the first tube, wherein the marks are positioned on one side of the balloon away from the distal end of the first tube, and all the marks are distributed at intervals along the longitudinal direction of the first tube.

In one embodiment, the single balloon catheter with the drug injection and blocking functions further comprises a developing ring sleeved at the distal end of the first tube, and the developing ring is positioned at one side of the balloon close to the distal end of the first tube.

In one embodiment, the first through holes are arranged in a plurality, all the first through holes are distributed at intervals along the longitudinal direction of the first pipe, and the second through holes are arranged in a plurality corresponding to the first through holes.

In one embodiment, the first tube further comprises a longitudinally extending guide wire channel for threading a guide wire.

In a second aspect, the present application provides an injection device, which adopts the following technical scheme:

The injection equipment comprises the single balloon catheter with the drug injection and blocking functions, an input assembly and a linking assembly, wherein the input assembly comprises a plurality of input pipe fittings, the input pipe fittings are communicated with the proximal end of the single balloon catheter with the drug injection and blocking functions, and the linking assembly is arranged on the periphery of the input pipe fittings and the connecting part of the single balloon catheter with the drug injection and blocking functions in a surrounding mode.

In a third aspect, the present application provides an operation method of a single balloon catheter with drug injection and blocking functions, which is applied to the single balloon catheter with drug injection and blocking functions, and comprises the following steps:

A single balloon catheter with the drug injection and blocking functions is sent into a human body by means of an endoscope;

Determining an injection position under the observation of an endoscope image;

injecting a filling medium into the balloon to expand the balloon to be fixed at the injection site;

Injecting medicine into human body;

The medicine is placed in the human body for at least more than a preset time;

Withdrawing the infused drug;

And extracting the filling medium and taking out the single balloon catheter with the drug injection and blocking functions.

In one embodiment, the injecting the drug into the human body comprises:

Switching the single balloon catheter with the drug injection and blocking functions from a closed state to a working state;

selecting an opening position according to injection requirements;

The limiting piece is switched to a corresponding opening position;

the drug is released into the human body.

The single balloon catheter with the functions of drug injection and blocking is always in a closed state before injection operation, and the first through hole is not communicated with the second through hole, so that the drug stored in the second pipe fitting is not easy to be polluted by the outside, and the drug effect is reduced. After the single balloon catheter with the functions of drug injection and blocking is inserted into the corresponding position, the balloon is inflated to block the lumen and fix the catheter at the lesion part, and then the catheter is switched to a working state, so that the drug in the catheter is ensured to be pollution-free and bacteria-free by virtue of the first through hole and the second through hole Kong Shichu, and the therapeutic effect is improved. Moreover, due to the arrangement of the saccule, hormone medicine can be fully mixed and soaked with the wound surface above the saccule, so that the perfusion effect can be maintained for a long time, and the clinical curative effect is further improved.

Drawings

Fig. 1 is a schematic view of a single balloon catheter with drug injection and occlusion functions according to an embodiment of the present application.

FIG. 2 is a cross-sectional view of a single balloon catheter with drug injection and occlusion functions in the direction of A-A in accordance with one embodiment of the present application.

FIG. 3 is a cross-sectional view in the direction B-B of a single balloon catheter with drug injection and occlusion functions in accordance with one embodiment of the present application.

Fig. 4 is a schematic view of an injection device according to an embodiment of the present application.

The drawings are marked with the following description:

1. Single saccule catheter with medicine injection and blocking functions; 11. a first pipe fitting; 111. an injection channel; 112. filling the channel; 113. a guidewire channel; 114. a first through hole; 115. a limit groove; 12. a second pipe fitting; 121. a drug administration channel; 122. a second through hole; 13. a limiting piece; 14. an opening rib; 15. a balloon; 151. filling the cavity; 16. marking; 17. a developing ring; 2. an input assembly; 21. a drug administration tube; 22. filling the pipe fitting; 23. a guidewire tube; 3. a joining assembly; f1, longitudinal direction; f2, radial direction.

Detailed Description

In order that the above objects, features and advantages of the application will be readily understood, a more particular description of the application will be rendered by reference to the appended drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. The present application may be embodied in many other forms than described herein and similarly modified by those skilled in the art without departing from the spirit of the application, whereby the application is not limited to the specific embodiments disclosed below.

In the description of the present application, it should be understood that, if any, these terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., are used herein with respect to the orientation or positional relationship shown in the drawings, these terms refer to the orientation or positional relationship for convenience of description and simplicity of description only, and do not indicate or imply that the apparatus or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the application.

Furthermore, the terms "first," "second," and the like, if any, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present application, the terms "plurality" and "a plurality" if any, mean at least two, such as two, three, etc., unless specifically defined otherwise.

In the present application, unless explicitly stated and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly. For example, the two parts can be fixedly connected, detachably connected or integrated; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art according to the specific circumstances.

In the present application, unless expressly stated or limited otherwise, the meaning of a first feature being "on" or "off" a second feature, and the like, is that the first and second features are either in direct contact or in indirect contact through an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.

It will be understood that if an element is referred to as being "fixed" or "disposed" on another element, it can be directly on the other element or intervening elements may also be present. If an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein, if any, are for descriptive purposes only and do not represent a unique embodiment.

It is specifically noted that in the description of the present application, those skilled in the art will understand that the terms "proximal" and "distal" are relative to the operator unless specifically stated and defined otherwise; the "proximal end" is the end of the endoscope operating handle that is closer to the user in one dimension when being held and operated, and the "distal end" is the end of the endoscope operating handle that is farther from the user in one dimension when being held and operated. And those skilled in the art will appreciate that the terms "distal" and "proximal" do not refer to a straight line distance from the user's three-dimensional space.

Submucosal dissection (Endoscopic submucosal dissection, ESD) via endoscope refers to endoscopic minimally invasive surgery using various endoscopic electrotomes to submucosally dissect early lesions of the digestive tract greater than 2 cm. The technique realizes the whole excision of a larger lesion part and provides accurate case diagnosis stage for the lesion.

Compared with the traditional surgery, the ESD can better maintain the physiological functions of the digestive tract on the basis of tumor resection, thereby obviously improving the postoperative life quality of patients, and is currently the first choice treatment method for early cancers and precancerous lesions of the digestive tract including esophagus.

A common complication after large area esophageal lesions ESD surgery is luminal stenosis, which is also one of the pain spots in the clinic at present. To solve this problem, the methods commonly used at present are: the treatment schemes of hormone oral administration, hormone injection, expansion, stent installation and the like, but the actual effect is not exact, and the repeatability cannot be ensured. The early-stage published clinical research shows that the short-course oral administration of the hormone has better combined hormone soaking effect and can obviously reduce the incidence rate of esophageal lumen stenosis.

In the process of intracavity hormone injection and soaking diagnosis and treatment, firstly, the gas in the gastric cavity and the esophageal cavity is required to be sucked out, and then a certain amount of hormone diluent is injected into the esophageal cavity, but due to peristaltic movement of the lumen itself and choking cough possibly occurring in operation, the retention time of the medicine in the lumen is uncontrollable, and the treatment effect is affected.

Therefore, in order to solve the problems, the application provides a catheter which can seal the lumen in a period of time so as to ensure that the medicine is fully mixed and soaked in the wound surface, in particular to a single balloon catheter with the functions of medicine injection and sealing.

Embodiments of the present application are described in further detail below with reference to FIGS. 1-4.

Referring to fig. 1 and 2, fig. 1 is a schematic partial view of a single balloon catheter with drug injection and blocking functions according to an embodiment of the present application, and fig. 2 is a cross-sectional view of a single balloon catheter with drug injection and blocking functions according to an embodiment of the present application in a direction A-A. An embodiment of the present application provides a single balloon catheter 1 with drug injection and blocking functions, comprising a first tube 11 and a second tube 12 stacked in the first tube 11. The first tube member 11 includes an injection passage 111 extending in the longitudinal direction F1, the injection passage 111 penetrating through an end face of the proximal end of the first tube member 11 to form an insertion port into which the second tube member 12 is inserted, the second tube member 12 being slidably mounted in the injection passage 111 through the insertion port.

In the embodiment of the present application, in order to facilitate the sliding operation of the second pipe 12 in the injection channel 111, an oil film layer is coated on the inner wall of the injection channel 111, so as to reduce the friction resistance between the outer wall of the second pipe and the inner wall of the injection channel 111. The oil film layer may be, for example, glycerol, or other liquid with lubricating effect, which is not limited herein.

In addition, in order to facilitate the single balloon catheter 1 with the functions of drug injection and blocking to be smoothly inserted into the natural cavity of the human body for administration, the first tube member 11 and the second tube member 12 in the embodiment of the application are made of flexible materials, and may be specifically made of polyurethane materials.

Referring to fig. 3, fig. 3 shows a cross-sectional view of a single balloon catheter B-B with drug injection and occlusion functions in accordance with an embodiment of the present application. Specifically, the first tube 11 includes a first through hole 114 disposed on the sidewall, and the first through hole 114 communicates with the injection channel 111 along the radial direction F2, so as to communicate the injection channel 111 with the outside.

The second tube member 12 includes a drug delivery channel 121 and a second through hole 122 provided in a side wall, wherein the drug delivery channel 121 extends in a longitudinal direction F1 and penetrates an end surface of a proximal end of the second tube member 12 to form a drug delivery port through which a drug is injected into the drug delivery channel 121 for delivery. The second through hole 122 communicates with the above-mentioned administration passage 121 in the radial direction F2 for communicating the administration passage 121 with the first through hole 114, thereby releasing the medicine to the outside to perform a therapeutic operation.

In the embodiment of the application, the medicine can be a hormone liquid medicine. It will be appreciated that in other embodiments, the medicament may be other kinds of medicaments, and the medicament is selected adaptively according to actual operation conditions, which is not limited in the present application.

As shown in fig. 2 and 3, in some embodiments, the single balloon catheter 1 with the drug injection and blocking functions includes a closed state and an operating state, and when the drug injection is not needed, the single balloon catheter 1 with the drug injection and blocking functions maintains the closed state, and the inside of the single balloon catheter is isolated from the outside, so that the drug stored in the catheter is not easy to be polluted by air, and the drug effect is ensured.

After the single balloon catheter 1 with the drug injection and blocking functions is inserted into a human body, the single balloon catheter 1 is switched to a working state, and at the moment, the liquid medicine inside the single balloon catheter 1 with the drug injection and blocking functions directly contacts with a lesion part after flowing out of the catheter, so that the possibility that the drug is polluted by the outside is low, the drug input into the human body is ensured to be pollution-free and bacteria-free as far as possible, and the treatment effect is improved.

In the embodiment of the present application, when the single balloon catheter 1 with both drug injection and blocking functions is in a closed state, the distal end of the first through hole 114 contacts with the distal end of the second through hole 122, and the first through hole 114 and the second through hole 122 are not overlapped in the radial direction F2, i.e., the second through hole 122 is blocked by the side wall of the first tube 11, so that the drug solution is isolated in the drug administration channel 121, and is prevented from being polluted due to contact with the outside.

When the single balloon catheter 1 with the functions of drug injection and blocking is in a working state, at least partial coincidence exists between the first through hole 114 and the second through hole 122 in the radial direction F2, so that the drug injected into the drug administration channel 121 can flow to the outside through the second through hole 122 and the first through hole 114 in sequence, and the drug administration operation on the lesion part is completed.

In addition, along with the sliding operation of the second tube 12 in the first tube 11, the area of the overlapping portion between the first through hole 114 and the second through hole 122 is also changed, so as to control the drug flow, so as to adapt to different drug administration requirements of different patients.

With continued reference to fig. 3, in some embodiments, in order to further ensure the smoothness of the switching between the closed state and the working state of the single balloon catheter 1 with the drug injection and the blocking function, the single balloon catheter 1 with the drug injection and the blocking function further includes a limiting member 13, where the limiting member 13 is adhered or integrally formed to the outer wall of the second tube 12, and as shown in fig. 3, the limiting member 13 is connected to the second tube 12 by adopting an adhering manner.

Specifically, the first pipe fitting 11 is internally provided with the limiting groove 115 extending along the longitudinal direction F1, the limiting piece 13 is slidably mounted in the limiting groove 115, and the side wall of the limiting piece 13 is in contact with the groove wall of the limiting groove 115, so that the limitation on the circumferential position of the second pipe fitting 12 is realized, the second pipe fitting 12 is not easy to twist in the first pipe fitting 11, and therefore, the first through hole 114 and the second through hole 122 can at least partially overlap in the circumferential direction in the sliding process of the second pipe fitting 12, and the single balloon catheter 1 with the functions of drug injection and blocking is further ensured to be freely switched between a closed state and a working state.

With continued reference to fig. 2 and 3, the stop 13 includes a closed position and a plurality of open positions spaced from the closed position. Wherein, the closed position is correspondingly arranged at the distal end of the limit groove 115. When the stopper 13 is in the closed position, the first through hole 114 and the second through hole 122 are offset from each other in the radial direction F2, and the drug solution is blocked in the drug delivery channel 121. The plurality of opening positions are arranged on one side of the closed position close to the proximal end of the limiting groove 115, and all the closed positions are distributed from the distal end of the limiting groove 115 to the proximal end of the limiting groove 115.

In the embodiment of the application, the adjacent opening positions are distributed at equal intervals, so that an operator can monitor the medicine injection efficiency corresponding to the current opening in real time according to the opening positions. In other embodiments, the spacing between adjacent opening positions may also be unequal to accommodate different dosing requirements for different treatment procedures.

Further, in order to facilitate the operator to perceive the real-time position of the limiting member 13, in some embodiments, the single balloon catheter 1 with the functions of drug injection and blocking further includes a plurality of opening ribs 14 disposed in the limiting groove 115, and the opening ribs 14 are disposed in one-to-one correspondence with the opening positions.

In the embodiment of the application, three opening ribs 14 are arranged from the far end to the near end of the limiting groove 115, and the three opening ribs 14 are uniformly distributed in the limiting groove 115 and are connected with the groove wall of the side, away from the limiting piece 13, of the limiting groove 115. In the embodiment of the present application, the opening rib 14 may be connected to the first pipe 11 by bonding or integrally forming, as shown in fig. 3, which is only the connection achieved by bonding, it is understood that in other embodiments, the opening rib 14 and the first pipe 11 may be configured as an integral structure.

Specifically, in the radial direction F2 of the first pipe fitting 11, at least a part of the opening rib 14 and the limiting member 13 overlap, that is, in the sliding process of the second pipe fitting 12, the end portion of the limiting member 13 can be abutted against the end portion of the opening rib 14, and in the actual operation process, an operator can determine the size of the communication area between the first through hole 114 and the second through hole 122 by counting the number of times of the withdrawal resistance felt when withdrawing the second pipe fitting 12.

It should be noted that, in the embodiment of the present application, the opening rib 14 and the limiting member 13 are made of flexible materials, so as to ensure that the opening rib can be elastically deformed under the condition that the opening rib and the limiting member are partially overlapped in the radial direction F2, so that the second pipe fitting 12 can slide smoothly.

Referring to fig. 3 specifically, in the embodiment of the present application, the opening ribs 14 are specifically set to three, and the three opening ribs 14 are uniformly distributed along the extending direction of the limiting groove 115, and different openings between the opening ribs 14 and the adjacent opening ribs 14 or the wall of the limiting groove 115 define the first through hole 114 and the second through hole 122.

Specifically, from the distal end to the proximal end of the limiting groove 115, the opening degrees are respectively set to 33%, 66% and 100%, so as to meet different injection requirements of different patients. It will be appreciated that in other embodiments, more opening positions may be provided and more opening ribs 14 may be correspondingly provided, thereby improving the accuracy of the dosing rate adjustment.

Referring to fig. 1, in some embodiments, the single balloon catheter 1 with drug injection and blocking functions further includes a balloon 15 mounted on the first tube 11, and the balloon 15 is closer to the distal end of the first tube 11 than the first through hole 114. In the embodiment of the application, the balloon 15 is arranged to be capable of stretching along the radial direction F2, so as to be clamped and fixed on the lesion part of a patient, thereby realizing the fixation of the single balloon catheter 1 with the functions of drug injection and blocking. Specifically, a filling cavity 151 is disposed in the balloon 15, and a filling channel 112 is further disposed in the first tube 11 along the longitudinal direction F1, and the filling channel 112 is disposed at a distance from the injection channel 111. Wherein the filling channel 112 is connected to the filling cavity 151 for injecting a filling medium into the filling cavity 151, and the diameter of the balloon 15 is changed along with the change of the volume of the injected filling medium. Wherein, balloon 15 and first pipe fitting 11 integrated into one piece lay to promote balloon 15's gas tightness.

In the embodiment of the application, the filling material can be any one of liquid or gas. The balloon 15 is made of an elastic material, and may specifically be any one of a silica gel, a rubber, and a polyurethane material, as long as the change in the size of the balloon 15 in the radial direction F2 can be easily achieved. In addition, the diameter of the balloon 15 is set to 15mm or 20mm to fit the diameter requirement of the natural lumen of the human body.

In the actual diagnosis and treatment process, a patient lies on the back at an angle of about 45 degrees, the single balloon catheter 1 with the drug injection and blocking functions is inserted into a lumen through an endoscope biopsy pore canal, the distal end of the single balloon catheter 1 with the drug injection and blocking functions is sent to the lower part of an ESD wound surface, filling media are injected into the balloon 15 to enable the balloon 15 to be fixed at the position after being inflated, then the single balloon catheter 1 with the drug injection and blocking functions is switched to a working state, and drugs (particularly diluted hormone solution) are released into the lumen, so that the drugs can be fully mixed and soaked above the balloon and the wound surface, the drugs can be kept in effective contact with the wound surface for a long time, the accurate treatment of the lesion part is realized, the drug injection amount required by single injection treatment is reduced, and the clinical curative effect is improved.

In addition, the single balloon catheter 1 with the drug injection and blocking functions can be applied to patients with esophageal varices bleeding. The esophageal varices bleeding caused by portal hypertension is clinically severe, the blood vessel rupture bleeding or pinhole bleeding after the hardening agent is injected under an endoscope, the saccule 15 can be used for compression hemostasis, the saccule 15 plays a role in blocking the compression hemostasis of the blood vessel, and the time can be strived for the next treatment.

In other embodiments, as shown in fig. 1, the first through holes 114 and the second through holes 122 may be provided in plural numbers, and the first through holes 114 and the second through holes 122 are arranged in a one-to-one correspondence. Along the longitudinal direction F1 of the first tube 11, all the first through holes 114 are distributed at intervals, so as to ensure that the medicine stored in the single balloon catheter 1 with the functions of medicine injection and blocking can be smoothly released, and improve the operation reliability.

In the embodiment of the present application, only two first through holes 114 and two second through holes 122 are illustrated as examples, and the two first through holes 114 are respectively disposed at positions of 3cm and 5cm near the balloon 15.

With continued reference to fig. 1, in some embodiments, the single balloon catheter 1 with drug injection and blocking functions further includes a plurality of markers 16 disposed on the periphery of the first tube 11, where the markers 16 are spaced apart from the first through hole 114. The marks 16 in the present application are particularly marker marks, the marks 16 are located on one side of the balloon 15 away from the first tube 11, and all the marks 16 are distributed at intervals along the longitudinal direction F1 of the first tube 11, so that an operator can confirm the position to be injected according to the marks 16.

In other embodiments, the single balloon catheter 1 with the functions of drug injection and blocking also comprises a developing ring 17 sleeved on the distal end of the first tube 11, wherein the developing ring 17 is positioned on one side of the balloon 15 close to the distal end of the first tube 11, and the developing ring 17 is used for marking 16 the irradiation range of the quality sub-beam so as to assist an operator in determining a lesion site.

Referring to fig. 2, in some embodiments, the first tube 11 further includes a guide wire channel 113 extending along the longitudinal direction F1, where the guide wire channel 113 is respectively spaced from the injection channel 111 and the filling channel 112, and the guide wire channel 113 is used for threading a guide wire, so as to guide the whole single balloon catheter 1 with drug injection and blocking functions to a desired position, thereby achieving accurate treatment.

Referring to fig. 1 to 4, fig. 4 is a schematic view of an injection device according to an embodiment of the present application, and in some embodiments, the present application further provides an injection device, including a single balloon catheter 1 with drug injection and blocking functions as shown in any of the above embodiments, and an input assembly 2 connected to the single balloon catheter 1 with drug injection and blocking functions.

Specifically, the input assembly 2 includes a plurality of input tubes, in the embodiment of the present application, three input tubes are provided corresponding to the number of channels in the first tube 11 and the second tube 12, namely, an administration tube 21 for communicating with the administration channel 121, a filling tube 22 for communicating with the filling channel 112, and a wire tube 23 for communicating with the wire channel 113, so as to facilitate the operation of the single balloon catheter 1 having both the drug injection and the blocking functions.

In addition, in some other embodiments, the injection device further includes a linking component 3 disposed at a linking portion of the input tube and the single balloon catheter 1 with the drug injection and blocking functions, the linking component 3 includes a receiving cavity (not shown), and all distal portions of the input tube and proximal portions of the single balloon catheter 1 with the drug injection and blocking functions are received in the receiving cavity, so that effective protection of a connecting portion between the single balloon catheter 1 with the drug injection and blocking functions and the input tube is achieved, so as to prolong a service life of the injection device.

In other embodiments, the present application further provides an operation method of the single balloon catheter 1 with drug injection and blocking functions, which is applied to the single balloon catheter 1 with drug injection and blocking functions in any of the above embodiments, and the operation method specifically includes the following operation steps:

S1: a single balloon catheter 1 with the drug injection and blocking functions is sent into a human body by means of an endoscope;

s2: determining an injection position under the observation of an endoscope image;

s3: injecting a filling medium into balloon 15 to inflate balloon 15 to secure in the injection site;

S4: injecting medicine into human body;

S5: the medicine is placed in the human body for at least more than a preset time;

s6: withdrawing the infused drug;

s7: the filling medium is extracted and the single balloon catheter 1 with the drug injection and blocking functions is taken out.

In step S1, the patient is required to lie on his back at an angle of about 45 °, the single balloon catheter 1 with the drug injection and blocking functions is inserted into the forceps channel of the endoscope, and the single balloon catheter 1 with the drug injection and blocking functions is delivered into the human body by means of the endoscope.

In step S2, the part to be filled, that is, the lesion part is determined under the observation of the endoscopic image, and the position to be filled is confirmed based on the marker mark.

In step S5, the preset time is set to 10 minutes, and in the actual operation process, the preset time can be correspondingly increased or decreased according to different conditions of the patient, so long as the medicine is ensured to be fully absorbed by the human body.

In step S6, the medicine injected into the natural cavity of the human body is reversely withdrawn through the administration channel 121 after the treatment is completed, so as to avoid the aspiration of the patient after the operation.

In step S7, the filling medium is withdrawn to shrink the balloon 15 and push out the endoscopic forceps channel.

In the operation process, an operator can observe the operation infusion process under direct vision, control the injection quantity of the medicine according to the marker mark, and observe the condition of the target tissue after the medicine is administrated.

The step S4 specifically includes the following steps:

s41: switching the single balloon catheter 1 with the drug injection and blocking functions from a closed state to a working state;

S42: selecting an opening position according to injection requirements;

s43: the limiting piece 13 is switched to a corresponding opening position;

S44: the drug is released into the human body.

The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.

The above examples illustrate only a few embodiments of the application, which are described in detail and are not to be construed as limiting the scope of the claims. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the application, which are all within the scope of the application. Accordingly, the scope of protection of the present application is to be determined by the appended claims.

Claims (13)

1. A single balloon catheter with drug injection and blocking functions, comprising:

a first pipe (11) comprising a first through hole (114) provided in the side wall;

a balloon (15) in communication with the first tube (11), the balloon (15) being closer to the distal end of the first tube (11) than the first through hole (114), the balloon (15) being configured to be expandable and contractible in a radial direction (F2) such that the balloon (15) is adapted to occlude a lumen of an esophagus; and

A second tube (12) penetrating the first tube (11), wherein the second tube (12) comprises a drug delivery channel (121) for delivering a drug, and a second through hole (122) arranged on the side wall and communicated with the drug delivery channel (121), and the second through hole (122) can be communicated with the first through hole (114) and the drug delivery channel (121) so as to release the drug to the outside;

wherein, single sacculus pipe (1) that has medicine injection concurrently, shutoff function includes closure state and operating condition: when in a closed state, the first through hole (114) and the second through hole (122) are not coincident in the radial direction (F2); in the operating state, the first through hole (114) and the second through hole (122) are at least partially coincident in the radial direction (F2).

2. The single balloon catheter with the drug injection and blocking functions according to claim 1, wherein the single balloon catheter (1) with the drug injection and blocking functions further comprises a limiting piece (13), a limiting groove (115) extending along the longitudinal direction (F1) is arranged in the first pipe fitting (11), and the limiting piece (13) is connected to the outer wall of the second pipe fitting (12) and is slidably mounted in the limiting groove (115).

3. The single balloon catheter with the functions of drug injection and blocking according to claim 2, wherein the limiting piece (13) comprises a closed position and a plurality of opening positions which are distributed at intervals with the closed position, the closed position is correspondingly arranged at the distal end of the limiting groove (115), and all the opening positions are distributed at intervals from the distal end of the limiting groove (115) to the proximal end of the limiting groove (115);

When the single balloon catheter (1) with the drug injection and blocking functions is in a closed state, the limiting piece (13) is switched to the closed position, so that the drug is blocked in the second pipe fitting (12);

When the single balloon catheter (1) with the medicine injection and blocking functions is in a working state, the limiting piece (13) can be switched to any opening position, and the first through hole (114) is communicated with the second through hole (122) so that medicine is released.

4. A single balloon catheter with drug injection and plugging function according to claim 3, wherein the single balloon catheter (1) with drug injection and plugging function further comprises a plurality of opening ribs (14) arranged in a limit groove (115), the opening ribs (14) are arranged corresponding to the opening positions, and the opening ribs (14) can be in contact with the limit piece (13) in the radial direction (F2) of the first tube (11).

5. The single balloon catheter with drug injection and blocking functions according to claim 1, wherein a filling cavity (151) is built in the balloon (15), the first tube (11) further comprises a filling channel (112), the filling channel (112) is communicated with the filling cavity (151) for injecting filling medium into the filling cavity (151), and the balloon (15) can stretch along the longitudinal direction (F1) along with the change of the volume of the injected filling medium.

6. The single balloon catheter with drug injection and blocking functions according to claim 5, wherein the balloon (15) is made of elastic materials, including silicone, rubber and polyurethane materials.

7. The single balloon catheter with drug injection and blocking function according to claim 1, wherein the single balloon catheter (1) with drug injection and blocking function further comprises a plurality of marks (16) arranged on the first tube (11), the marks (16) are positioned on one side of the balloon (15) far away from the distal end of the first tube (11), and all the marks (16) are distributed at intervals along the longitudinal direction (F1) of the first tube (11).

8. The single balloon catheter with the drug injection and blocking functions according to claim 1, wherein the single balloon catheter (1) with the drug injection and blocking functions further comprises a developing ring (17) sleeved at the distal end of the first pipe fitting (11), and the developing ring (17) is positioned at one side of the balloon (15) close to the distal end of the first pipe fitting (11).

9. The single balloon catheter with the drug injection and blocking functions according to claim 1, wherein a plurality of first through holes (114) are provided, all of the first through holes (114) are spaced apart along the longitudinal direction (F1) of the first tube member (11), and the second through holes (122) are provided in plurality corresponding to the first through holes (114).

10. The single balloon catheter with drug injection and occlusion function according to claim 1, wherein the first tube (11) further comprises a guide wire channel (113) extending in a longitudinal direction (F1), the guide wire channel (113) being adapted for threading a guide wire.

11. An injection device, characterized in that it comprises:

Single balloon catheter (1) with drug injection and occlusion functions according to any of the claims 1-10;

An input assembly (2) comprising a plurality of input pipe fittings which are communicated with the proximal end of the single balloon catheter (1) with the drug injection and blocking functions; and

The connecting component (3) is arranged around the periphery of the connecting part of the input pipe fitting and the single balloon catheter (1) with the drug injection and blocking functions.

12. A method for operating a single balloon catheter with drug injection and blocking functions, which is applied to the single balloon catheter with drug injection and blocking functions as set forth in any one of claims 1 to 10, and is characterized in that the method comprises the following steps:

A single balloon catheter (1) with the drug injection and blocking functions is sent into a human body by an endoscope;

Determining an injection position under the observation of an endoscope image;

Injecting a filling medium into the balloon (15) to expand the balloon (15) to be fixed at the injection position;

Injecting medicine into human body;

The medicine is placed in the human body for at least more than a preset time;

Withdrawing the infused drug;

Extracting the filling medium and taking out the single balloon catheter (1) with the drug injection and blocking functions.

13. The method of operating a single balloon catheter with drug injection and occlusion functions of claim 12, the injecting drug into a human body comprising:

switching a single balloon catheter (1) with the drug injection and blocking functions from a closed state to a working state;

selecting an opening position according to injection requirements;

the limiting piece (13) is switched to a corresponding opening position;

the drug is released into the human body.