CN118078719A - Wet tissue composition for eyes as well as preparation method and application thereof - Google Patents

Wet tissue composition for eyes as well as preparation method and application thereof Download PDF

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Publication number
CN118078719A
CN118078719A CN202410042940.0A CN202410042940A CN118078719A CN 118078719 A CN118078719 A CN 118078719A CN 202410042940 A CN202410042940 A CN 202410042940A CN 118078719 A CN118078719 A CN 118078719A
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CN
China
Prior art keywords
parts
wet wipe
extract
eyes
nonionic surfactant
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CN202410042940.0A
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Chinese (zh)
Inventor
陈璐
史权
吴东旭
邓洪英
杨艳
吴思敏
王小兰
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Shanghai Dongli Great Health Research Institute Co ltd
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Shanghai Dongli Great Health Research Institute Co ltd
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Priority to CN202410042940.0A priority Critical patent/CN118078719A/en
Publication of CN118078719A publication Critical patent/CN118078719A/en
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Abstract

The invention relates to the technical field of daily necessities, in particular to a wet tissue composition for eyes as well as a preparation method and application thereof. The wet wipe composition comprises 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer, and water. The wet tissue composition for eyes can achieve the effects of anti-inflammatory, antibacterial and relieving by the synergistic interaction of 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water, and is suitable for sensitive skin, especially the skin around eyes.

Description

Wet tissue composition for eyes as well as preparation method and application thereof
Technical Field
The invention relates to the technical field of daily necessities, in particular to a wet tissue composition for eyes as well as a preparation method and application thereof.
Background
People often contact dust, computer, cell-phone radiation, automobile exhaust, haze and kitchen oil smoke etc. among them harmful substance all can get into eyes, cause uncomfortable such as eyes portion dryness, when the eyes secretion is too much or have the foreign matter, people are used to the hand, water or ordinary paper handkerchief wipe eyes, easily infects the bacterium, appears the inflammation even. Many people then choose to use eye drops. However, after the eye drops are added, the eye drops remain on the skin of eyes, and the eyes are required to be rubbed by paper towels or hands, so that the eyes are polluted. Most of the wet tissues for eyes on the current market aim at daily cleaning and makeup removal demands, but few products consider the demands of relieving and anti-inflammatory, so that it is very necessary to design the wet tissues for eyes with anti-inflammatory, antibacterial and relieving functions.
Disclosure of Invention
In order to solve the technical problems, the invention provides a wet tissue composition for eyes and a preparation method and application thereof.
According to a first aspect of the present invention, there is provided a wet wipe composition for eyes comprising 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water.
In the scheme, the wet tissue composition for eyes comprises 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water, wherein the 4-terpineol has the functions of resisting oxidation, resisting bacteria, expelling parasites and killing mites, is mainly used as an anti-inflammatory agent, an anti-parasitic agent, an anti-tumor agent and a flavoring agent, can be widely used for treating acne, acne rosacea and demodex infection, and is suitable for sensitive skin. Sodium hyaluronate has deep moisturizing effect, and can increase skin elasticity. Vitamin E has antioxidant and protecting effects, and helps to reduce free radical injury. The Hamamelis extract is extracted from bark, branches and leaves of Hamamelis shrub native to North America, has hemostatic and antiinflammatory effects, and can calm skin and reduce redness and swelling. The nonionic surfactant has cleaning effect. The oat extract is a whole plant extract of oat of Gramineae, mainly contains beta-glucan, flavonoid compounds and various antioxidant substances, has excellent anti-aging effect, can smooth fine wrinkles, improves skin texture, and further increases anti-inflammatory and relieving effects. The antiseptic can inhibit microorganism activity, prevent wet towel from spoilage, and maintain product stability. The stabilizing agent maintains the wettability of the wet wipe and helps the skin retain moisture. The wet tissue composition for eyes can achieve the effects of anti-inflammatory, antibacterial and relieving through the synergistic interaction of 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water, and is suitable for sensitive skin, especially skin around eyes.
In order to better achieve the anti-inflammatory, antibacterial and soothing effects, further, the wet tissue composition comprises the following components in parts by weight: 1-2 parts of 4-terpineol, 0.1-1 part of sodium hyaluronate, 0.1-0.3 part of vitamin E, 1-2 parts of witch hazel extract, 1-3 parts of nonionic surfactant, 0.1-1 part of oat extract, 0.1-1 part of preservative, 1-3 parts of stabilizer and 90-95 parts of water.
In order to better achieve the anti-inflammatory, antibacterial and soothing effects, further, the wet tissue composition comprises the following components in parts by weight: 1.5 parts of 4-terpineol, 0.5 part of sodium hyaluronate, 0.2 part of vitamin E, 1.5 parts of witch hazel extract, 2 parts of nonionic surfactant, 0.5 part of oat extract, 0.5 part of preservative, 2 parts of stabilizer and 91.3 parts of water.
Further, the nonionic surfactant is cocoa amidopropyl betaine.
In the scheme, the cocoa amidopropyl betaine serving as the nonionic surfactant has the advantages of cleaning effect, mild property and suitability for sensitive skin.
Further, the preservative is phenoxyethanol.
In the scheme, the phenoxyethanol is used as the preservative, so that the preservative effect can be achieved, and the skin is not stimulated.
Further, the stabilizer is glycerol.
In the scheme, the glycerol keeps the wettability of the wet tissues, helps the skin to keep moisture, and achieves the effect of stabilizing the skin.
According to a second aspect of the present invention, there is also provided a method of preparing the wet wipe composition described above, comprising the steps of: mixing 4-terpineol, sodium hyaluronate, vitamin E, hamamelis mollis extract, nonionic surfactant, herba Avenae Fatuae extract, antiseptic, stabilizer and water.
Further, the temperature of the mixing is 40-60 ℃, preferably 50 ℃.
According to a third aspect of the present invention there is also provided the use of a wet wipe composition as described above in an ophthalmic wet wipe.
Further, the wet wipe composition is applied to a biodegradable nonwoven fabric to ensure uniform wetting, resulting in a wet wipe for the eye.
There are two packaging forms of wet tissues for eyes, the first is to package wet tissues for eyes in a sealed package to maintain the wettability and the ingredient stability thereof. Secondly, the wet tissue composition and the biodegradable non-woven fabric are packaged separately, when the wet tissue composition is needed to be used, the wet tissue composition contained in the package is folded for 3 times, and the package is lightly pressed, so that the wet tissue composition is fully contacted with the biodegradable non-woven fabric; then tearing along the opening, taking out the wet tissue for eyes, winding the wet tissue on the index finger of the right hand, closing the eyes, and cleaning the skin around the eyes.
The technical scheme provided by the invention has the following beneficial effects:
The wet tissue composition for eyes can achieve the effects of resisting inflammation, resisting bacteria and relieving through the mutual synergistic effect of 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water, and is suitable for sensitive skin, especially skin around eyes.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
All the raw materials used in the following examples and comparative examples are commercially available, except for the specific descriptions.
Examples 1 to 5, comparative examples 1 to 2
Examples 1-5 and comparative examples 1-2 each independently provided a wet wipe composition for eyes, which was prepared by the following method, with the raw materials composition shown in table 1 below, in parts by weight: mixing 4-terpineol, sodium hyaluronate, vitamin E, hamamelis mollis extract, nonionic surfactant, herba Avenae Fatuae extract, antiseptic, stabilizer and water at 50deg.C. Wherein the nonionic surfactant is cocoa amide propyl betaine, the preservative is phenoxyethanol, and the stabilizer is glycerol.
TABLE 1
Comparative example 3
This comparative example provides a wet wipe composition for the eye which differs from example 1 in that the same amount of camphor is used instead of 4-terpineol.
The wet wipe composition for eye use of this comparative example was prepared in the same manner as in example 1.
Comparative example 4
This comparative example provides a wet wipe composition for the eye, which differs from example 1 in that the same amount of kuh-seng extract is used instead of witch hazel extract.
The wet wipe composition for eye use of this comparative example was prepared in the same manner as in example 1.
Comparative example 5
This comparative example provides a wet wipe composition for the eye, which differs from example 1 in that the oat extract is replaced with the same amount of honeysuckle extract.
The wet wipe composition for eye use of this comparative example was prepared in the same manner as in example 1.
Experimental example
The wet wipe compositions for eyes prepared in the above examples and comparative examples were subjected to anti-inflammatory, antibacterial, soothing and skin safety tests, and the specific test results are shown in tables 2 to 4 below:
1. Antibacterial performance test: the sterilization effect test is carried out on the wet tissue composition for eyes according to the sterilization technical specification, wherein the sterilization effect of the wet tissue composition for eyes on staphylococcus aureus ATCC6538 and escherichia coli ATCC8739 is tested for 30s, 2min and 5min according to the bacterial quantitative sterilization test of the sterilization technical specification 2.1.1.7; the ophthalmic wet wipe composition was tested for 30s, 2min, 5min sterilization effect on candida albicans ATCC10231 according to the sterilization technical Specification 2.1.1.9 fungus killing test, and the results are shown in tables 2-4.
TABLE 2
TABLE 3 Table 3
TABLE 4 Table 4
2. Relaxation performance test
The test method is as follows:
Subject selection criteria: 200 women aged 20-50 years old, from which sensitive skin, periocular skin had inflammation and had erythema, were divided into 10 groups of 20 persons each, and the ocular wet tissues prepared by using the ocular wet tissue compositions of examples 1-5 and comparative examples 1-5 were tested, respectively, and were used twice daily, once in the morning, and once before sleep; the subject has no external application, oral administration or injection of other products which can affect the test for nearly 1 month, including skin care products with effects of relieving, repairing and the like, and the products cannot be used during the test; periocular sites have not been subjected to skin treatments, cosmetics, and other tests that may affect the results.
The testing method comprises the following steps: subjects participated in the test, and a cross-polarized photograph of Visia-CR taken images was selected and isolated to obtain erythema photographs. By means of the photo, erythema, inflammatory injury, telangiectasia and the like of the lower layer of the skin can be observed, so that whether the cosmetics can irritate the skin or have a soothing effect on the skin can be judged. And calculating the skin erythema area change of the selected area by using IPP software, and averaging the two sides. The decrease rates of the areas of erythema after 15 days and 30 days were measured for each subject in each group, and the average value was calculated to obtain the decrease rates of the areas of erythema after 15 days and 30 days for each group of subjects, respectively, and the measurement results are shown in table 5 below.
TABLE 5
3. Skin safety test
The test method is patch test, 300 adults are selected as test objects, the ages are between 20 and 25 years, the interior of the arm forearm is selected, and the skin state is observed after 24 hours. The test results are shown in table 6 below.
TABLE 6
From the experimental results, the wet tissue composition for eyes can achieve the effects of resisting inflammation, resisting bacteria and relieving through the synergistic interaction of 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water, and is suitable for sensitive skin, especially skin around eyes.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1. A wet wipe composition for eyes, comprising 4-terpineol, sodium hyaluronate, vitamin E, witch hazel extract, nonionic surfactant, oat extract, preservative, stabilizer and water.
2. The wet wipe composition of claim 1 wherein the wet wipe composition comprises, in parts by weight: 1-2 parts of 4-terpineol, 0.1-1 part of sodium hyaluronate, 0.1-0.3 part of vitamin E, 1-2 parts of witch hazel extract, 1-3 parts of nonionic surfactant, 0.1-1 part of oat extract, 0.1-1 part of preservative, 1-3 parts of stabilizer and 90-95 parts of water.
3. The wet wipe composition of claim 2 wherein the wet wipe composition comprises, in parts by weight: 1.5 parts of 4-terpineol, 0.5 part of sodium hyaluronate, 0.2 part of vitamin E, 1.5 parts of witch hazel extract, 2 parts of nonionic surfactant, 0.5 part of oat extract, 0.5 part of preservative, 2 parts of stabilizer and 91.3 parts of water.
4. The wet wipe composition of claim 1 wherein the nonionic surfactant is cocoa amidopropyl betaine.
5. The wet wipe composition of claim 1 wherein the preservative is phenoxyethanol.
6. The wet wipe composition of claim 1 wherein the stabilizing agent is glycerin.
7. A method of preparing a wet wipe composition according to any one of claims 1-6, comprising the steps of: mixing 4-terpineol, sodium hyaluronate, vitamin E, hamamelis mollis extract, nonionic surfactant, herba Avenae Fatuae extract, antiseptic, stabilizer and water.
8. The preparation method according to claim 7, wherein the temperature of the mixing is 40-60 ℃, preferably 50 ℃.
9. Use of the wet wipe composition of any one of claims 1-6 on an ophthalmic wet wipe.
10. The use according to claim 9, characterized in that the wet wipe composition is applied to a biodegradable nonwoven ensuring uniform wetting to obtain a wet wipe for the eye.
CN202410042940.0A 2024-01-11 2024-01-11 Wet tissue composition for eyes as well as preparation method and application thereof Pending CN118078719A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410042940.0A CN118078719A (en) 2024-01-11 2024-01-11 Wet tissue composition for eyes as well as preparation method and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202410042940.0A CN118078719A (en) 2024-01-11 2024-01-11 Wet tissue composition for eyes as well as preparation method and application thereof

Publications (1)

Publication Number Publication Date
CN118078719A true CN118078719A (en) 2024-05-28

Family

ID=91143127

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202410042940.0A Pending CN118078719A (en) 2024-01-11 2024-01-11 Wet tissue composition for eyes as well as preparation method and application thereof

Country Status (1)

Country Link
CN (1) CN118078719A (en)

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