CN1180751C - 椎间植入物 - Google Patents

椎间植入物 Download PDF

Info

Publication number
CN1180751C
CN1180751C CNB998168734A CN99816873A CN1180751C CN 1180751 C CN1180751 C CN 1180751C CN B998168734 A CNB998168734 A CN B998168734A CN 99816873 A CN99816873 A CN 99816873A CN 1180751 C CN1180751 C CN 1180751C
Authority
CN
China
Prior art keywords
intervertebral implant
hollow cylinder
cylinder body
implant according
degree
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB998168734A
Other languages
English (en)
Other versions
CN1367669A (zh
Inventor
��Ŭ������ɳ��
曼努埃尔·沙尔
热罗姆·伯恩哈德
康拉德·塔格威尔克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AO Technology AG
Original Assignee
Synthes AG Chur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes AG Chur filed Critical Synthes AG Chur
Publication of CN1367669A publication Critical patent/CN1367669A/zh
Application granted granted Critical
Publication of CN1180751C publication Critical patent/CN1180751C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/025Joint distractors
    • A61B2017/0256Joint distractors for the spine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/3008Properties of materials and coating materials radio-opaque, e.g. radio-opaque markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30131Rounded shapes, e.g. with rounded corners horseshoe- or crescent- or C-shaped or U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30138Convex polygonal shapes
    • A61F2002/30158Convex polygonal shapes trapezoidal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30182Other shapes
    • A61F2002/30187D-shaped or half-disc-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30593Special structural features of bone or joint prostheses not otherwise provided for hollow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30777Oblong apertures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30784Plurality of holes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082Grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30904Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves serrated profile, i.e. saw-toothed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0013Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017Angular shapes
    • A61F2230/0026Angular shapes trapezoidal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/0034D-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Abstract

本发明涉及一种具有一个空心圆柱体形状的椎间植入物,它具有一个盖表面(1)、一个基表面(2)、一个带有一个外侧表面(4)和一个内侧表面(5)的空心圆柱体壁(3),以及一个空心圆柱体中心轴线(6)。该植入物至少百分之九十五的体积由X射线通透材料组成,该材料的弹性模量为1到20Gpa。该植入物允许通过X射线进行术后观察,同时其特点是具有高度的生物适应性。

Description

椎间植入物
技术领域
本发明涉及一种如权利要求1的前序部分所述的椎间植入物。
背景技术
从DE-A 196 15 938中已知一种椎间植入物,该椎间植入物由细长金属板制成并且因此对X射线不具有通透性。
这种公知的植入物的缺点在于其对X射线的不透明性,这种不透明性使得术后对椎骨体合并情况的观察成为不可能。
从US-A-5 192 327 BRANTIGAN中已知一种由碳纤维强化塑料制造的相应类型的椎间植入物。该植入物的缺点是由于塑料的强化,该植入物的弹性性能与其周围的骨头的弹性性能不一致。
发明内容
本发明意在纠正上述缺点。因此本发明的一个目的是提供一种椎间植入物,该椎间植入物允许通过X射线进行术后观察,同时其特点是具有高度的生物适应性。
本发明通过一种具有权利要求1所述特征的椎间植入物而实现了所述的目的。此外X射线通透材料的相对较低的弹性模量通常还有利于骨头理想地生长在所述植入物上。
适当的X射线通透材料包括例如聚醚醚酮(Polyetheretherketone)(PEEK),超高分子量聚乙烯(UHMWPE)或聚砜(PSU),特别是那种弹性模量为3到5GPa的材料。
根据本发明的一个优选的改进,该椎间植入物至少带一个由对X射线不透明的材料制成的标记,该标记的体积最多占椎间植入物的总体积的百分之五。这样尽管有新骨的生长,也能在X射线照片中表明植入物的位置。该标记最好由钛或钽制成,并且为小销或小球的形状。
根据本发明的一个优选的改进,盖表面和基表面都带有一个三维尺寸的结构表面,最好是规则配置,例如为球缺形布置的齿的形状。
优选的形式是,盖表面和基表面相互配置成楔形,其楔形的角度例如为10到20度。
根据本发明的一个优选的改进,盖表面和/或基表面可以带一个或多个朝着空心圆柱体轴线的导向槽口。从该空心圆柱体轴线(6)处看,这些导向槽口最好配置成45度±15度的角度。
空心圆柱体的盖表面DF与其内侧表面所确定的空心圆柱体部分的自由横截表面FQF之比DF/FQF应该适当地在0.5到1.6的范围内。
根据本发明的另一个优选的改进,该空心圆柱体的壁有一个朝着该空心圆柱体轴线并且从盖表面延伸到基表面的凹槽。在其较高的一侧,空心圆柱体壁最好有一个平行于空心圆柱体轴线并且从盖表面达到基表面的分隔狭缝,该分隔狭缝使该植入物有U形的形状。从空心圆柱体轴线处看,凹槽最好被配置在空心圆柱体壁上与分隔狭缝相对的一侧。
后凹槽使该植入物适当地坐落在椎骨体的终板上。这样,就可能获得高度的基本稳定性。如此达到的配合精度有助于防止植入物侧向位移。
分隔狭缝促使椎骨体的终板上的骨头尽可能迅速地从前侧长入到植入物中。另外,分隔狭缝可以在原地被填充(例如由骨头片填充)。优选的形式是,分隔狭缝的宽度为6到10mm。
根据本发明的进一步的改进,外侧表面上带有一个或多个夹持槽口,这些槽口与空心圆柱体轴线呈直角地延伸,并且距盖表面和基表面有相等的距离。优选的形式是,包括几个槽口,从凹槽处看,这些槽口偏置了90度和/或240度。特别有利的是还提供另外两个偏置180度并且通到分隔狭缝的槽口。
根据本发明的进一步改进,空心圆柱体壁上带有一些孔,这些孔形如圆孔、狭缝或长孔。从凹槽处看,这些孔被配置成0度、90度或240度。
对于在脊柱腰椎段内的应用,该椎间植入物的高度最好在12到23mm范围内;对于在脊柱颈椎段内的应用,其高度应在4.5到12.5mm范围内。
对于用于脊柱腰椎段的植入物,从空心圆柱体中心轴线向外测量,其外侧表面延伸的最大距离最好为14到18mm。
对于用于脊柱颈椎段的植入物,从空心圆柱体中心轴线向外测量,其外侧表面延伸的最大距离最好为5.5到9.5mm。
附图说明
下面,将参考一个实施例的局部示意性示图,对本发明及其改进进行更详细的描述。
在图中:
图1是椎间植入物的透视图;和
图2是图1所示椎间植入物的侧视图。
具体实施方式
图1和图2所示的椎间植入物具有一个空心的圆柱体的形状。它具有一个盖表面1、一个基表面2、一个包括一个外侧表面4和一个内侧表面5的空心圆柱体壁3,以及一个空心圆柱体中心轴线6。
该植入物至少有百分之九十五的体积由X射线通透材料如PEEK(聚芳基醚酮polyaryletherketones)组成。所用的材料具有的弹性模量必须在1到20GPa之间。最好该弹性模量在3到5GPa之间。
该椎间植入物还带有三个由对X射线不透明的材料(钛或钽)制成的标记(图中没有显示),这三个标记总共的体积最多占所说椎间植入物的体积的百分之五。作为总体积(100%)应理解为由椎间植入物的材料所占的体积,排除由植入物所包围的空心空间。
植入物的盖表面1和基表面2都带有一个三维尺寸的结构表面10,该结构表面10由一些规则配置在一个球缺中的齿构成。植入物的球缺形配置的齿(再加上植入物的楔形形状)使盖表面和基表面成为弯曲部分,这反过来又使得植入物最适当地座落于椎骨体的终板上。
如图2可见,盖表面1和基表面2相互配置成楔形,形成了一个大约为10到20度的角度。
在盖表面1和基表面2上,植入物带有几个侧向的和前侧向的导向槽口11,这些槽口朝着空心圆柱体轴线6。这些导向槽口用于通过牵引设备的刀片,将植入物插入到扩张的椎间腔中。偏置的成对槽口允许植入物从侧向、前侧向和前面插入。
从空心圆柱体轴线6处看,导向槽口11偏置45度±15度。
从图1中可见,在空心圆柱体壁3上带有一个朝着空心圆柱体轴线6并且从盖表面1延伸到基表面2的后凹槽9。在其较高的(前面的)一侧,该空心圆柱体壁3上有一个分隔狭缝7,该分隔狭缝7平行于空心圆柱体轴线6并且从盖表面1延伸到基表面2,该分隔狭缝使该植入物有U形的形状。从空心圆柱体轴线6处看,该凹槽9配置在空心圆柱体壁3上与分隔狭缝相对的一侧。
外侧表面4上带有两个侧夹持槽口8,这些槽口与空心圆柱体轴线呈直角地延伸,并且距盖表面1和基表面2有相等的距离。从凹槽9处看,夹持槽口8偏置90度和240度。
另外,还包括两个附加的前夹持槽口8,这些槽口偏置180度并且通到分隔狭缝7。
夹持槽口的功能是,一方面避免在植入物保持装置上的轴向扭转,另一方面为该设备提供了平面接触表面。
该空心圆柱体壁3带有至少一个椭圆形孔12,从凹槽9处看,该孔12偏置90度。

Claims (27)

1.一种空心圆柱体形的椎间植入物,它具有一个盖表面(1)、一个基表面(2)、一个带有一个外侧表面(4)和一个内侧表面(5)的空心圆柱体壁(3),以及一个空心圆柱体中心轴线(6),该植入物的至少百分之九十五的体积由X射线通透材料组成,其特征在于:该植入物由具有1到20GPa的弹性模量的材料组成。
2.根据权利要求1的椎间植入物,其特征在于:植入物由具有3到5GPa的弹性模量的材料组成。
3.根据权利要求1或2的椎间植入物,其特征在于:该植入物带有至少一个由对X射线不透明的材料制成的标记。
4.根据权利要求3的椎间植入物,其特征在于:该至少一个的标记的总体积最多占所说椎间植入物的体积的百分之五。
5.根据权利要求1或2的椎间植入物,其特征在于:盖表面(1)和基表面(2)带有一个三维尺寸的结构表面(10)。
6.根据权利要求5的椎间植入物,其特征在于:该三维尺寸的结构表面(10)由一些最好是以规则形式配置的齿组成。
7.根据权利要求5的椎间植入物,其特征在于:该三维尺寸的结构表面(10)由一些球缺形式配置的齿组成。
8.根据权利要求1或2的椎间植入物,其特征在于:盖表面(1)和基表面(2)相互配置为楔形。
9.根据权利要求8的椎间植入物,其特征在于:盖表面(1)相对于基表面(2)形成10到20度的角度。
10.根据权利要求1或2的椎间植入物,其特征在于:X射线通透材料是从聚芳基醚酮(Polyaryletherketone)族中选择出来的。
11.根据权利要求1或2的椎间植入物,其特征在于:盖表面(1)和/或基表面(2)带有一个或几个朝着空心圆柱体轴线(6)的导向槽口(11)。
12.根据权利要求11的椎间植入物,其特征在于:从空心圆柱体轴线(6)处看,导向槽口(11)偏置45度±15度的角度。
13.根据权利要求1或2的椎间植入物,其特征在于:空心圆柱体的盖表面(1)DF与其内侧表面(5)所确定的空心圆柱体部分的自由横截表面FQF之比DF/FQF应该适当地在0.5到1.6的范围内。
14.根据权利要求1或2的椎间植入物,其特征在于:空心圆柱体壁(3)带有一个朝向空心圆柱体轴线(6)并且从盖表面(1)延伸到基表面(2)的凹槽(9)。
15.根据权利要求8的椎间植入物,其特征在于:在其较高一侧,该空心圆柱体壁(3)上有一个分隔狭缝(7),该分隔狭缝(7)平行于空心圆柱体轴线(6)并且从盖表面(1)延伸至基表面(2),该分隔狭缝使该植入物具有U形形状。
16.根据权利要求14的椎间植入物,其特征在于:从空心圆柱体轴线(6)处看,凹槽(9)配置在空心圆柱体壁(3)上与分隔狭缝(7)相对的一侧。
17.根据权利要求1或2的椎间植入物,其特征在于:外侧表面(4)带有一个或几个夹持槽口(8),这些槽口(8)与空心圆柱体轴线(6)呈直角地延伸,并且距盖表面(1)和基表面(2)有相等的距离。
18.根据权利要求17的椎间植入物,其特征在于:还包括几个夹持槽口(8),从凹槽(9)处看,这些槽口(8)偏置90度和/或240度。
19.根据权利要求17的椎间植入物,其特征在于:还包括另外两个夹持槽口(8),这两个夹持槽口(8)偏置180度并且通到分隔狭缝(7)。
20.根据权利要求1或2的椎间植入物,其特征在于:空心圆柱体壁(3)上带有一些孔(12)。
21.根据权利要求20的椎间植入物,其特征在于:所述的孔(12)形如圆孔、狭缝或长孔。
22.根据权利要求21的椎间植入物,其特征在于:从凹槽(9)处看,所述孔(12)偏置0度、90度或240度。
23.根据权利要求1或2的椎间植入物,其特征在于:其高度在12到23mm的范围内。
24.根据权利要求1或2的椎间植入物,其特征在于:其高度在4.5到12.5mm的范围内。
25.根据权利要求1或2的椎间植入物,其特征在于:从空心圆柱体中心轴线(6)向外测量,其外侧表面(4)延伸的最大距离为14到18mm。
26.根据权利要求1或2的椎间植入物,其特征在于:从空心圆柱体中心轴线(6)向外测量,其外侧表面(4)延伸的量大距离为5.5到9.5mm。
27.根据权利要求1或2的椎间植入物,其特征在于:所述的X射线通透材料是从聚醚醚酮(PEEK)族、超高分子量聚乙烯(UHMWPE)或聚砜(PSU)中选择出来的。
CNB998168734A 1999-08-27 1999-08-27 椎间植入物 Expired - Fee Related CN1180751C (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1999/006332 WO2001015637A1 (de) 1999-08-27 1999-08-27 Zwischenwirbel-implantat

Publications (2)

Publication Number Publication Date
CN1367669A CN1367669A (zh) 2002-09-04
CN1180751C true CN1180751C (zh) 2004-12-22

Family

ID=8167409

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998168734A Expired - Fee Related CN1180751C (zh) 1999-08-27 1999-08-27 椎间植入物

Country Status (13)

Country Link
US (1) US7303583B1 (zh)
EP (1) EP1207821B1 (zh)
JP (1) JP4883860B2 (zh)
CN (1) CN1180751C (zh)
AT (1) ATE272373T1 (zh)
AU (1) AU754038B2 (zh)
CA (1) CA2405259C (zh)
DE (1) DE59910154D1 (zh)
DK (1) DK1207821T3 (zh)
ES (1) ES2224695T3 (zh)
HK (1) HK1043298B (zh)
PT (1) PT1207821E (zh)
WO (1) WO2001015637A1 (zh)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2897259B1 (fr) 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si Cage intersomatique transforaminale a greffon de fusion intervetebrale et instrument d'implantation de la cage
FR2799639B1 (fr) 1999-10-18 2002-07-19 Dimso Sa Prothese de disque intervertebral a faces dentees
US7018416B2 (en) * 2000-07-06 2006-03-28 Zimmer Spine, Inc. Bone implants and methods
DE10116412C1 (de) 2001-04-02 2003-01-16 Ulrich Gmbh & Co Kg Implantat zum Einsetzen zwischen Wirbelkörper der Wirbelsäule
US6719794B2 (en) * 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
DK175391B1 (da) * 2002-02-13 2004-09-20 Danfoss As Implantat til columna og fremgangsmåde til fremstilling heraf
DE50213818D1 (de) * 2002-03-12 2009-10-15 Cervitech Inc Intrumentarium zum Einsetzen einer Zwischenwirbelprothese
WO2004026187A1 (en) 2002-09-19 2004-04-01 Malan De Villiers Intervertebral prosthesis
US7192447B2 (en) 2002-12-19 2007-03-20 Synthes (Usa) Intervertebral implant
EP1587437B1 (en) 2003-01-31 2013-02-27 Spinalmotion, Inc. Spinal midline indicator
JP4275699B2 (ja) 2003-01-31 2009-06-10 スパイナルモーション, インコーポレイテッド 椎骨間プロテーゼ配置器具
DE202004021289U1 (de) 2003-05-14 2007-06-06 Kraus, Kilian Höhenverstellbares Implantat zum Einsetzen zwischen Wirbelkörpern und Handhabungswerkzeug
US10052211B2 (en) 2003-05-27 2018-08-21 Simplify Medical Pty Ltd. Prosthetic disc for intervertebral insertion
US7575599B2 (en) 2004-07-30 2009-08-18 Spinalmotion, Inc. Intervertebral prosthetic disc with metallic core
WO2004105638A2 (en) 2003-05-27 2004-12-09 Spinalmotion, Inc. Prosthetic disc for intervertebral insertion
DE20320974U1 (de) 2003-12-11 2005-08-25 Deltacor Gmbh Längenverstellbares Wirbelsäulen-Implantat
US7918891B1 (en) 2004-03-29 2011-04-05 Nuvasive Inc. Systems and methods for spinal fusion
US7585326B2 (en) 2004-08-06 2009-09-08 Spinalmotion, Inc. Methods and apparatus for intervertebral disc prosthesis insertion
US7763024B2 (en) * 2004-09-23 2010-07-27 Spine Solutions, Inc. Adjustable cutting of cutout in vertebral bone
TWI327064B (en) 2004-09-23 2010-07-11 Spine Solutions Inc An intervertebral implant
US7780731B2 (en) * 2004-11-26 2010-08-24 Spine Solutions, Inc. Intervertebral implant
US8083797B2 (en) 2005-02-04 2011-12-27 Spinalmotion, Inc. Intervertebral prosthetic disc with shock absorption
DE202005009273U1 (de) * 2005-06-09 2005-10-20 Ohst Medizintechnik Ag Implantat zum Einfügen zwischen benachbarten Wirbelkörpern
FR2891135B1 (fr) 2005-09-23 2008-09-12 Ldr Medical Sarl Prothese de disque intervertebral
JP2009533187A (ja) 2006-04-12 2009-09-17 スパイナルモーション, インコーポレイテッド 後方脊椎の装置および方法
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
US8673005B1 (en) 2007-03-07 2014-03-18 Nuvasive, Inc. System and methods for spinal fusion
FR2916956B1 (fr) 2007-06-08 2012-12-14 Ldr Medical Cage intersomatique,prothese intervertebrale,dispositif d'ancrage et instrumentation d'implantation
US20090043391A1 (en) 2007-08-09 2009-02-12 Spinalmotion, Inc. Customized Intervertebral Prosthetic Disc with Shock Absorption
WO2009055478A1 (en) 2007-10-22 2009-04-30 Spinalmotion, Inc. Vertebral body replacement and method for spanning a space formed upon removal of a vertebral body
US8945221B2 (en) * 2007-12-05 2015-02-03 Pat Barrett Anterior lumbar interbody graft
US9101491B2 (en) 2007-12-28 2015-08-11 Nuvasive, Inc. Spinal surgical implant and related methods
US8083796B1 (en) 2008-02-29 2011-12-27 Nuvasive, Inc. Implants and methods for spinal fusion
US9034038B2 (en) 2008-04-11 2015-05-19 Spinalmotion, Inc. Motion limiting insert for an artificial intervertebral disc
EP2278941A1 (en) 2008-05-05 2011-02-02 Spinalmotion Inc. Polyaryletherketone artificial intervertebral disc
US9220603B2 (en) 2008-07-02 2015-12-29 Simplify Medical, Inc. Limited motion prosthetic intervertebral disc
WO2010009151A2 (en) 2008-07-17 2010-01-21 Spinalmotion, Inc. Artificial intervertebral disc placement system
EP2299941A1 (en) 2008-07-18 2011-03-30 Spinalmotion Inc. Posterior prosthetic intervertebral disc
US8147554B2 (en) * 2008-10-13 2012-04-03 Globus Medical, Inc. Intervertebral spacer
US20100094426A1 (en) * 2008-10-14 2010-04-15 Grohowski Jr Joseph A Hybrid intervertebral spinal implant
USD621509S1 (en) 2008-10-15 2010-08-10 Nuvasive, Inc. Intervertebral implant
CA2749684C (en) 2009-01-16 2016-04-26 Carbofix Orthopedics Ltd. Composite material bone implant
USD754346S1 (en) 2009-03-02 2016-04-19 Nuvasive, Inc. Spinal fusion implant
US9387090B2 (en) * 2009-03-12 2016-07-12 Nuvasive, Inc. Vertebral body replacement
US8641766B2 (en) 2009-04-15 2014-02-04 DePuy Synthes Products, LLC Arcuate fixation member
US9408715B2 (en) 2009-04-15 2016-08-09 DePuy Synthes Products, Inc. Arcuate fixation member
US20100268278A1 (en) * 2009-04-15 2010-10-21 Warsaw Orthopedic, Inc. Tension band
BRPI1012883B8 (pt) * 2009-07-09 2021-06-22 R Tree Innovations Llc dispositivo intercorporal
CN105326585B (zh) 2009-09-17 2018-12-11 Ldr控股公司 具有可伸展骨固定部件的椎间植入件
US9801732B2 (en) * 2009-10-30 2017-10-31 Spinefrontier, Inc System and method for an intervertebral implant assembly
EP3323390A1 (en) 2009-12-31 2018-05-23 LDR Medical Système intervertébral avec un dispositif d'ancrage
EP2547292B1 (en) 2010-03-16 2019-04-24 Pinnacle Spine Group, LLC Ntervertebral implants and graft delivery systems
CN105167830B (zh) 2010-06-07 2018-06-12 卡波菲克斯整形有限公司 复合材料骨植入物
US10154867B2 (en) 2010-06-07 2018-12-18 Carbofix In Orthopedics Llc Multi-layer composite material bone screw
US9119728B2 (en) 2011-01-17 2015-09-01 Cibor, Inc. Reinforced carbon fiber/carbon foam intervertebral spine fusion device
US8545563B2 (en) 2011-02-02 2013-10-01 DePuy Synthes Product, LLC Intervertebral implant having extendable bone fixation members
US9132021B2 (en) 2011-10-07 2015-09-15 Pioneer Surgical Technology, Inc. Intervertebral implant
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
USD675320S1 (en) 2011-11-03 2013-01-29 Nuvasive, Inc. Intervertebral implant
US8926666B2 (en) * 2011-11-23 2015-01-06 Globus Medical, Inc. Cervical spine spacer
US9526549B2 (en) 2012-01-16 2016-12-27 Carbofix Orthopedics Ltd. Bone screw with insert
CN102579167A (zh) * 2012-01-19 2012-07-18 冠亚生技股份有限公司 一种复合层次脊椎椎间复位装置
WO2014110182A1 (en) 2013-01-08 2014-07-17 Praxis Powder Technology, Inc. High strength injection molded orthopedic devices
CN103142331B (zh) * 2013-02-26 2016-01-06 广州聚生生物科技有限公司 寰枢侧块关节融合器
US10070970B2 (en) 2013-03-14 2018-09-11 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems
FR3005569B1 (fr) 2013-05-16 2021-09-03 Ldr Medical Implant vertebral, dispositif de fixation vertebrale d'implant et instrumentation d'implantation
USD745159S1 (en) 2013-10-10 2015-12-08 Nuvasive, Inc. Intervertebral implant
CN103932824A (zh) * 2014-04-16 2014-07-23 王红军 一种医用钛笼
FR3020756B1 (fr) 2014-05-06 2022-03-11 Ldr Medical Implant vertebral, dispositif de fixation vertebrale d'implant et instrumentation d'implantation
USD858769S1 (en) 2014-11-20 2019-09-03 Nuvasive, Inc. Intervertebral implant
US10617458B2 (en) 2015-12-23 2020-04-14 Carbofix In Orthopedics Llc Multi-layer composite material bone screw
US10624760B2 (en) 2017-05-22 2020-04-21 Warsaw Orthopedic, Inc. Spinal implant system and method
AU2018327353A1 (en) 2017-09-08 2020-03-19 Pioneer Surgical Technology, Inc. Intervertebral implants, instruments, and methods
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
US11766339B1 (en) 2017-10-24 2023-09-26 Omnia Medical, LLC Multi-material multi-component spinal implant
US10736752B1 (en) 2017-10-24 2020-08-11 Omnia Medical, LLC Multi-material multi-component spinal implant
US11759324B2 (en) * 2021-08-31 2023-09-19 Haroon Fiaz Choudhri Intervertebral implants having positioning grooves and kits and methods of use thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2632850B2 (ja) * 1987-05-30 1997-07-23 京セラ株式会社 人工椎体
GB8718627D0 (en) 1987-08-06 1987-09-09 Showell A W Sugicraft Ltd Spinal implants
US4960818A (en) * 1989-04-25 1990-10-02 The United States Of America As Represented By The Secretary Of The Navy Polymer composite preform and process for producing same
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
ATE191634T1 (de) * 1994-05-23 2000-04-15 Sulzer Spine Tech Inc Implantat zur intervertebralen fusion
USD397439S (en) * 1994-07-22 1998-08-25 Tibor Koros Spinal implant
US5782919A (en) * 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
FR2724312B1 (fr) * 1995-04-21 1997-09-12 Alby Albert Entretoise intersomatique
FR2733413B1 (fr) 1995-04-27 1997-10-17 Jbs Sa Dispositif de cage cervicale destine a la realisation d'une arthrodese intersomatique
DE59607458D1 (de) * 1995-10-20 2001-09-13 Synthes Ag Zwischenwirbel-implantat
JP3692169B2 (ja) * 1995-10-31 2005-09-07 京セラ株式会社 人工椎間スペーサ
DE59511075D1 (de) * 1995-11-08 2007-02-08 Zimmer Gmbh Vorrichtung zum Einbringen eines Implantats, insbesondere einer Zwischenwirbelprothese
US5766253A (en) * 1996-01-16 1998-06-16 Surgical Dynamics, Inc. Spinal fusion device
US5865845A (en) * 1996-03-05 1999-02-02 Thalgott; John S. Prosthetic intervertebral disc
US5676146B1 (en) * 1996-09-13 2000-04-18 Osteotech Inc Surgical implant containing a resorbable radiopaque marker and method of locating such within a body
US5860977A (en) * 1997-01-02 1999-01-19 Saint Francis Medical Technologies, Llc Spine distraction implant and method
US5749916A (en) * 1997-01-21 1998-05-12 Spinal Innovations Fusion implant
US6641614B1 (en) * 1997-05-01 2003-11-04 Spinal Concepts, Inc. Multi-variable-height fusion device
US5972368A (en) * 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US6511509B1 (en) * 1997-10-20 2003-01-28 Lifenet Textured bone allograft, method of making and using same
US6482233B1 (en) * 1998-01-29 2002-11-19 Synthes(U.S.A.) Prosthetic interbody spacer
US6143033A (en) * 1998-01-30 2000-11-07 Synthes (Usa) Allogenic intervertebral implant
US6241769B1 (en) * 1998-05-06 2001-06-05 Cortek, Inc. Implant for spinal fusion

Also Published As

Publication number Publication date
EP1207821A1 (de) 2002-05-29
AU754038B2 (en) 2002-10-31
JP2003508119A (ja) 2003-03-04
CN1367669A (zh) 2002-09-04
HK1043298A1 (en) 2002-09-13
US7303583B1 (en) 2007-12-04
DK1207821T3 (da) 2004-11-01
HK1043298B (zh) 2004-12-24
AU5856299A (en) 2001-03-26
PT1207821E (pt) 2004-12-31
WO2001015637A1 (de) 2001-03-08
ATE272373T1 (de) 2004-08-15
CA2405259C (en) 2005-12-06
DE59910154D1 (de) 2004-09-09
CA2405259A1 (en) 2001-03-08
JP4883860B2 (ja) 2012-02-22
EP1207821B1 (de) 2004-08-04
ES2224695T3 (es) 2005-03-01

Similar Documents

Publication Publication Date Title
CN1180751C (zh) 椎间植入物
CN1287752C (zh) 骨植入物,特别是椎间植入物及其制造方法
AU2005316646B2 (en) Inter-facet implant
US6503279B1 (en) Intervertebral implant
US7326251B2 (en) Interbody fusion device
CN1925799A (zh) 人工脊椎盘植入器械及方法
US20150081026A1 (en) Spinal Spacer
US7875034B2 (en) Spinal disc space preparation instruments and methods for interbody spinal implants
US8066749B2 (en) Implant for stabilizing a bone graft during spinal fusion
US20090275952A1 (en) Distractor
US11547569B2 (en) Anatomical wedge implant
US8262738B2 (en) Vertebral implant containment device and methods of use
US20110184468A1 (en) Spinous process fusion plate with osteointegration insert
CN1122686A (zh) 脊椎植入物
WO2007101006A1 (en) Prosthetic assembly for supporting a spinous process and method of implanting same
US20090187246A1 (en) Interbody implants for spinal alignment procedures
EP3795120B1 (en) Intervertebral implant and insertion device therefor
ZA200200338B (en) Intervertebral implant.
CA2264720C (en) Intervertebral implant

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: SYNTHES LTD.

Free format text: FORMER OWNER: SYNTHES AG CHUR

Effective date: 20061201

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20061201

Address after: Swiss Obbo Dov

Patentee after: Synthes AG

Address before: Swiss Kurdish

Patentee before: Chur Synthes AG

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20041222

Termination date: 20180827