CN117982225A - Method, device, equipment and medium for measuring geometric parameters of left ventricular outflow tract CSEPT - Google Patents

Method, device, equipment and medium for measuring geometric parameters of left ventricular outflow tract CSEPT Download PDF

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CN117982225A
CN117982225A CN202410404351.2A CN202410404351A CN117982225A CN 117982225 A CN117982225 A CN 117982225A CN 202410404351 A CN202410404351 A CN 202410404351A CN 117982225 A CN117982225 A CN 117982225A
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csept
determining
left ventricular
plane
mitral valve
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CN117982225B (en
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陈澍
张一宁
丁智豪
罗欢
张浩楠
罗园明
钱沛东
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Boyi Huixin Hangzhou Network Technology Co ltd
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Boyi Huixin Hangzhou Network Technology Co ltd
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Abstract

The embodiment of the invention discloses a method, a device, equipment and a medium for measuring geometric parameters of a left ventricular outflow tract CSEPT, wherein the method comprises the steps of constructing left ventricular and mitral valve models; determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model; determining CSEPT plane positions according to the left ventricular center line and the involution edge curve; determining CSEPT a measurement plane from the CSEPT plane location; and determining CSEPT parameter measurement values according to the CSEPT measurement planes. According to the scheme, the left ventricle and mitral valve model based on image reconstruction is used for carrying out CSEPT measurement area selection and related parameter measurement from a three-dimensional angle, the part needing human intervention in the overall process is greatly reduced, the measurement difficulty can be reduced, and the measurement time can be shortened.

Description

Method, device, equipment and medium for measuring geometric parameters of left ventricular outflow tract CSEPT
Technical Field
The invention relates to the technical field of left ventricular parameter measurement, in particular to a method, a device, equipment and a medium for measuring geometric parameters of a left ventricular outflow tract CSEPT.
Background
Myocardial resection of HOCM patients mainly depends on experience of operators, and too small resection range can not relieve obstruction, and too large resection range can lead to ventricular septal defects and lack of quantitative indexes. The spatial relationship of the mitral valve to the ventricular septum is of great significance to the evaluation LVOTO and the formulation of the surgical plan.
CSEPT refers to the space between the ventricular septum in the left ventricular outflow tract and the mitral valve coaptation margin. In febrile patients, the CSEPT space often presents a stenosis, impeding blood flow from the left ventricle to affect blood supply, due to ventricular hypertrophy and concomitant SAM symptoms. Maslow proposes a CSEPT geometric measurement scheme based on images, extracts the distance from the ventricular septum to the mitral valve involution edge and the area of the outflow tract from the images, and proves that the distance has negative correlation with the pressure difference of the outflow tract of the left ventricle, and has value in diagnosing the obstruction LVOTO of the outflow tract of the left ventricle.
Disclosure of Invention
In view of the foregoing, it is desirable to provide a method, apparatus, device and medium for measuring geometric parameters of left ventricular outflow tract CSEPT.
To achieve the above object, a first aspect of the present application provides a method for measuring a geometric parameter of a left ventricular outflow tract CSEPT, the method comprising:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
In some embodiments, the constructing the left ventricle and mitral valve model specifically includes:
Acquiring CT images of the end of the isovolumetric shrinkage period;
reconstructing a left ventricle and mitral valve model according to the CT image.
In some embodiments, the determining the left ventricular centerline and the coaptation curve according to the left ventricular and mitral valve model specifically includes:
extracting a left ventricular center line in the left ventricular and mitral valve model by taking an aortic valve leaflet aggregation point and a left ventricular apex point as control points;
and extracting a mitral valve involution edge curve from the left ventricle and mitral valve model.
In some embodiments, the determining CSEPT a plane position according to the left ventricular centerline and the coaptation curve specifically includes:
B spline interpolation is carried out on the central line of the left ventricle and the mitral valve involution edge curve, and analysis expression of two characteristic curves is obtained;
starting from the apex of the heart apex of the left ventricle, pushing along the direction of the central line of the left ventricle to the aortic valve, wherein the pushing step length is 1/1000 of the total length of the central line of the left ventricle;
And further, obtaining the tangential direction of the point on the central line of the left ventricle according to the B-spline interpolation result, and generating a plane which is perpendicular to the tangential direction and passes through the point, namely a CSEPT plane.
In some embodiments, the B-spline interpolation is performed on the left ventricular center line and the mitral valve coaptation edge curve to obtain analytical expressions of two characteristic curves, which specifically includes: according toDetermining B-spline interpolation results,/>Is a curve, B spline basis/>For node/>Corresponding/>Polynomial of degree/>Representing the highest order of B-spline basis,/>Also known as curve/>Or de Boor point.
In some embodiments, the determining CSEPT a measurement plane according to the CSEPT plane position specifically includes:
determining the shortest distance from the butt-edge curve to the CSEPT plane;
if the shortest distance is smaller than 0.5 unit of propulsion step length, cutting a left ventricle and a mitral valve model by a current plane to obtain a left heart outflow tract section;
If the shortest distance is greater than 0.5 unit of propulsion step length, continuing to propel along the center line of the left ventricle;
Dividing the determined left heart outflow tract section through mitral valve involution edge curve projection;
One side of the section belongs to the outflow channel, is reserved and used for measurement, and is marked as CSEPT measuring plane; the other side of the cross section is below the left atrium, independent of the outflow tract.
In some embodiments, the determining CSEPT a parameter measurement from the CSEPT measurement plane specifically includes:
determining CSEPT an area CSEPT-a of the measurement plane;
extracting two intersection points of projection of the involution edge curve on the left chamber outflow channel section and the chamber interval edge, and obtaining the distance between the intersection points by connecting lines, and marking the distance as a long axis L;
the equivalent width CSEPT-L of CSEPT is obtained by dividing the area CSEPT-A of the plane measured by the CSEPT by the long axis L.
To achieve the above object, a second aspect of the present application provides a device for measuring a geometric parameter of a left ventricular outflow tract CSEPT, the device comprising:
the model construction module is used for constructing left ventricle and mitral valve models;
the linear determining module is used for determining a central line of the left ventricle and an involution edge curve according to the left ventricle and mitral valve model;
the plane position determining module is used for determining CSEPT plane positions according to the central line of the left ventricle and the involution edge curve;
A measurement plane determining module for determining CSEPT a measurement plane based on the CSEPT plane position;
and the parameter determining module is used for determining CSEPT parameter measurement values according to the CSEPT measurement planes.
To achieve the above object, a third aspect of the present application provides a computer device comprising a memory and a processor, the memory storing a computer program which, when executed by the processor, causes the processor to perform the steps of:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
To achieve the above object, a fourth aspect of the present application provides a computer-readable storage medium storing a computer program which, when executed by a processor, causes the processor to perform the steps of:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
The embodiment of the invention has the following beneficial effects:
In the construction of the left ventricle and the mitral valve model, a three-dimensional model is reconstructed by utilizing an image, a measurement area is more clearly perceived, and then a left ventricle central line and an involution edge curve are determined according to the left ventricle and the mitral valve model; determining CSEPT plane positions according to the left ventricular center line and the involution edge curve; determining CSEPT a measurement plane from the CSEPT plane location; and the CSEPT parameter measurement value is determined according to the CSEPT measurement plane, the determination of the CSEPT measurement plane is based on three-dimensional geometric information, the subsequent parameter measurement is also fully automatic, the operation process is simple, the human factors are fewer, the measurement accuracy is higher, errors such as oblique cutting of an imaging plane are avoided, and the data repeatability is good.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Wherein:
FIG. 1 is a flow chart of a method of measuring geometric parameters of a left ventricular outflow tract CSEPT in one embodiment;
FIG. 2a is a schematic diagram illustrating a planar confirmation of a left ventricular outflow tract in a method for measuring a geometric parameter of the left ventricular outflow tract CSEPT in one embodiment;
FIG. 2b is another schematic plan view of a left ventricular outflow tract in a method of measuring a geometric parameter of the left ventricular outflow tract CSEPT in one embodiment;
FIG. 3a is a schematic diagram of a CSEPT measurement plane of a method for measuring geometric parameters of left ventricular outflow tract CSEPT in one embodiment;
FIG. 3b is another schematic illustration of a CSEPT measurement plane of a method of measuring a geometric parameter of a left ventricular outflow tract CSEPT in one embodiment;
FIG. 4 is a block diagram of a device for measuring geometric parameters of left ventricular outflow tract CSEPT in one embodiment;
FIG. 5 is a schematic diagram of a computer device in one embodiment;
FIG. 6 is a schematic diagram of a computer-readable storage medium in one embodiment.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In an embodiment of the present application, referring to fig. 1, fig. 1 is a flow chart illustrating a method for measuring a geometric parameter of a left ventricular outflow tract CSEPT in an embodiment, and the method for measuring a geometric parameter of a left ventricular outflow tract CSEPT includes steps S1 to S5.
Step S1, constructing a left ventricle and mitral valve model;
In some embodiments, the constructing the left ventricle and mitral valve model specifically includes:
Acquiring CT images of the end of the isovolumetric shrinkage period;
reconstructing a left ventricle and mitral valve model according to the CT image.
Specifically, during the complete cardiac cycle, the left ventricle is completely closed at the end of the isovolumetric contraction period, and the subsequent aortic valve is about to open to supply blood to the human body. Therefore, the left ventricular model of the end phase of the isovolumetric contraction is selected for measurement, and the state of the left ventricle before pumping can be estimated for effectively predicting the occurrence probability of outflow obstruction and SAM.
In the phase, the left ventricle is completely closed, so that rapid steady-state hemodynamic simulation cannot be performed, and the transient simulation is high in cost and does not meet the clinical timeliness requirement. According to the scheme, only geometric measurement of the left ventricle model is needed, the application cost and the time requirement are greatly reduced, quick and accurate evaluation can be achieved, the implementation of the method is based on the three-dimensional characteristics of the left ventricle, and compared with a two-dimensional image, the method is more representative, and the extracted related information is more comprehensive. And the manual operation is greatly reduced in the measurement process, and the repeatability of the measurement result is ensured.
Step S2, determining a left ventricular center line and an involution edge curve according to the left ventricular and mitral valve model;
in some embodiments, the determining the left ventricular centerline and the coaptation curve according to the left ventricular and mitral valve model specifically includes:
extracting a left ventricular center line in the left ventricular and mitral valve model by taking an aortic valve leaflet aggregation point and a left ventricular apex point as control points; reference is specifically made to the three-chamber tangential schematic of the method for measuring the geometric parameters of the left ventricular outflow tract CSEPT in one embodiment shown in fig. 2 a.
And extracting a mitral valve involution edge curve from the left ventricle and mitral valve model.
Specifically, the mitral valve coaptation curve contour is clearly visible from the mitral valve model, and the curve shape can be outlined by manual marking, specifically referring to the schematic diagram of CSEPT measurement plane in the method for measuring the geometric parameters of left ventricular outflow tract CSEPT in one embodiment shown in fig. 3 a.
S3, determining CSEPT plane positions according to the central line of the left ventricle and the involution edge curve;
In some embodiments, the determining CSEPT a plane position according to the left ventricular centerline and the coaptation curve specifically includes:
B spline interpolation is carried out on the central line of the left ventricle and the mitral valve involution edge curve, and analysis expression of two characteristic curves is obtained;
starting from the apex of the heart apex of the left ventricle, pushing along the direction of the central line of the left ventricle to the aortic valve, wherein the pushing step length is 1/1000 of the total length of the central line of the left ventricle;
And further, obtaining the tangential direction of the point on the central line of the left ventricle according to the B-spline interpolation result, and generating a plane which is perpendicular to the tangential direction and passes through the point, namely a CSEPT plane.
In particular, see fig. 2a and 2b, the selected plane (black) is perpendicular to the left ventricular outflow line (blue) and tangential to the mitral valve coaptation edge (red).
In some embodiments, the B-spline interpolation is performed on the left ventricular center line and the mitral valve coaptation edge curve to obtain analytical expressions of two characteristic curves, which specifically includes: according toDetermining B-spline interpolation results,/>Is a curve, B spline basis/>For node/>Corresponding/>Polynomial of degree/>Representing the highest order of B-spline basis,/>Also known as curve/>Or de Boor point.
Specifically, B-spline interpolation is carried out on the left ventricular center line and the mitral valve involution edge curve, the two characteristic curves are obtained in the same mode, and the B-spline interpolation structure is used for penetratingIndividual node/>Three-dimensional curve/>Obtaining the function/>, with the variable t,/>Correspondence/>Personal dot/>Distributed at/>Interval satisfies/>,/>,/>Numbering for nodes,/>By/>Personal/>Sub-B spline basis/>(Basic B-spline) composition,/>B spline basis/>For node/>Corresponding/>Polynomial of degree/>Representing the highest order of B-spline basis,/>Also referred to as curve/>Or de Boor point.
Further, for the nodeCorresponding/>Sub-B spline basis/>The:/>, can be defined by the Cox-de Boor recursive formula,/>
Step S4, determining CSEPT a measuring plane according to the CSEPT plane position;
In some embodiments, the determining CSEPT a measurement plane according to the CSEPT plane position specifically includes:
determining the shortest distance from the butt-edge curve to the CSEPT plane;
if the shortest distance is smaller than 0.5 unit of propulsion step length, cutting a left ventricle and a mitral valve model by a current plane to obtain a left heart outflow tract section;
If the shortest distance is greater than 0.5 unit of propulsion step length, continuing to propel along the center line of the left ventricle;
Dividing the determined left heart outflow tract section through mitral valve involution edge curve projection;
One side of the section belongs to the outflow channel, is reserved and used for measurement, and is marked as CSEPT measuring plane; the other side of the cross section is below the left atrium, independent of the outflow tract.
It should be noted that, the position of the outflow tract can be obtained by combining the three-dimensional model, and the plane part to be reserved is close to one side of the outflow tract. The position of the compartment space can also be used for judging, the reserved plane is formed by the projection of the joint edge curve and the compartment space inner film in a surrounding way, and the plane can be cut by using the projection of the joint edge curve on the plane CSEPT, and the part (green) on one side of the outflow channel is reserved for measuring the related CSEPT geometric parameters, as shown in fig. 3a and 3 b.
And step S5, determining CSEPT parameter measurement values according to the CSEPT measurement planes.
In some embodiments, the determining CSEPT a parameter measurement from the CSEPT measurement plane specifically includes:
determining CSEPT an area CSEPT-a of the measurement plane;
extracting two intersection points of projection of the involution edge curve on the left chamber outflow channel section and the chamber interval edge, and obtaining the distance between the intersection points by connecting lines, and marking the distance as a long axis L;
the equivalent width CSEPT-L of CSEPT is obtained by dividing the area CSEPT-A of the plane measured by the CSEPT by the long axis L.
Specifically, the equivalent width CSEPT-L of CSEPT is obtained by CSEPT-l= CSEPT-a/L, CSEPT-L in the existing 2D solution is the shortest distance from the coaptation edge to the ventricular septum, CSEPT-L defined in the present solution is the average distance from the ventricular septum to the anterior leaflet of the mitral valve, and is more representative of the stenosis degree of the CSEPT space.
By adopting the technical scheme of the embodiment, CT images of the end phases of the isovolumetric contraction period are selected, a left ventricle and a mitral valve model are constructed, selection of a CSEPT measurement area and relevant parameter measurement are carried out from a three-dimensional angle, as for parameters CSEPT-L, CSEPT-L in the existing 2D scheme is the shortest distance from the valvular edge to the ventricular interval, CSEPT-L defined by the scheme is the average distance from the ventricular interval to the anterior leaflet of the mitral valve, the stenosis degree of CSEPT space is more representative, the part needing human intervention in the overall flow of the scheme is greatly reduced, the measurement difficulty and time are improved, and in practical application, the method is beneficial to rapidly and nondestructively evaluating the heart obstruction degree and the anterior mitral valve contraction period forward motion (SAM) risk of a fat heart patient by acquiring the left ventricle geometric form of the end phases of the isovolumetric contraction period of an obstructive pulmonary heart disease HOCM patient, and measuring the geometric parameters of the left ventricle outflow tract.
In an embodiment of the present application, a device for measuring a geometric parameter of a left ventricular outflow tract CSEPT is provided, referring to fig. 4, a block diagram of a device for measuring a geometric parameter of a left ventricular outflow tract CSEPT in an embodiment of fig. 4, where the device for measuring a geometric parameter of a left ventricular outflow tract CSEPT includes: a model construction module 201, a linear determination module 202, a plane position determination module 203, a measurement plane determination module 204 and a parameter determination module 205.
Wherein the model construction module 201, the model construction module 201 is configured for constructing a left ventricular and mitral valve model;
A linearity determination module 202, the linearity determination module 202 being configured to determine a left ventricular centerline and a coaptation curve from the left ventricular and mitral valve models;
a planar position determination module 203, the planar position determination module 203 configured to determine CSEPT a planar position from the left ventricular centerline and a coaptation curve;
a measurement plane determination module 204, the measurement plane determination module 204 configured to determine CSEPT a measurement plane from the CSEPT plane location;
A parameter determination module 205, the parameter determination module 205 being configured for determining CSEPT a parameter measurement value from the CSEPT measurement planes.
In some embodiments, the model building module 201 is further configured to acquire CT images of the end of the isovolumetric shrinkage period;
reconstructing a left ventricle and mitral valve model according to the CT image.
In some embodiments, the wireform determination module 202 is further configured to extract a left ventricular centerline in the left ventricular and mitral valve model with an aortic valve leaflet aggregation point and a left ventricular apex as control points;
and extracting a mitral valve involution edge curve from the left ventricle and mitral valve model.
In some embodiments, the measurement plane determination module 204 is further configured to B-spline interpolate the left ventricular centerline and mitral valve coaptation curve to obtain an analytical representation of the two feature curves;
starting from the apex of the heart apex of the left ventricle, pushing along the direction of the central line of the left ventricle to the aortic valve, wherein the pushing step length is 1/1000 of the total length of the central line of the left ventricle;
And further, obtaining the tangential direction of the point on the central line of the left ventricle according to the B-spline interpolation result, and generating a plane which is perpendicular to the tangential direction and passes through the point, namely a CSEPT plane.
In some embodiments, the measurement plane determination module 204 is further configured to determine, based onDetermining B-spline interpolation results,/>Is a curve, B spline basis/>For node/>Corresponding/>Polynomial of degree/>Representing the highest order of B-spline basis,/>Also known as curve/>Or de Boor point.
In some embodiments, the measurement plane determination module 204 is further configured to determine a shortest distance of the coaptation curve to the CSEPT plane;
if the shortest distance is smaller than 0.5 unit of propulsion step length, cutting a left ventricle and a mitral valve model by a current plane to obtain a left heart outflow tract section;
If the shortest distance is greater than 0.5 unit of propulsion step length, continuing to propel along the center line of the left ventricle;
Dividing the determined left heart outflow tract section through mitral valve involution edge curve projection;
One side of the section belongs to the outflow channel, is reserved and used for measurement, and is marked as CSEPT measuring plane; the other side of the cross section is below the left atrium, independent of the outflow tract.
In some embodiments, the parameter determination module 205 is further configured to determine CSEPT an area CSEPT-a of the measurement plane;
extracting two intersection points of projection of the involution edge curve on the left chamber outflow channel section and the chamber interval edge, and obtaining the distance between the intersection points by connecting lines, and marking the distance as a long axis L;
the equivalent width CSEPT-L of CSEPT is obtained by dividing the area CSEPT-A of the plane measured by the CSEPT by the long axis L.
For further details of implementation of the above technical solution by each module in the device for measuring geometric parameters of the left ventricular outflow tract CSEPT, reference may be made to the description in the device for measuring geometric parameters of the left ventricular outflow tract CSEPT provided above, which is not repeated here.
In an embodiment of the present application, referring to fig. 5, fig. 5 is a schematic structural diagram of a computer device, where the computer device includes a memory 301 and a processor 302, and the memory 301 stores a computer program, and the computer program when executed by the processor 302 causes the processor 302 to perform the following steps:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
The processor 302 may also be called a CPU (Central Processing Unit ), and the processor 302 may be an integrated circuit chip with signal processing capability; the processor 402 may also be a general purpose processor, such as a microprocessor or the processor 302, or any conventional processor, DSP (DIGITAL SIGNAL processor), ASIC (Application SPECIFIC INTEGRATED Circuit), FPGA (Field Programmable GATA ARRAY, field programmable gate array) or other programmable logic device, discrete gate or transistor logic device, discrete hardware components.
In an embodiment of the present application, a computer readable storage medium is provided, please refer to fig. 6, fig. 6 is a schematic structural diagram of the computer readable storage medium in an embodiment, and the storage medium stores a readable computer program 401; the computer program 401 may be stored in the storage medium in the form of a software product, and includes several instructions to make a computer device (which may be a personal computer, a service machine, or a network device, etc.) or a processor (processor) execute the following steps:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
And the aforementioned storage medium includes: various media capable of storing program codes, such as a usb disk, a removable hard disk, a magnetic or optical disk, a ROM (Read-Only Memory), a RAM (Random Access Memory), or a terminal device such as a computer, a service machine, a mobile phone, a tablet.
Those skilled in the art will appreciate that all or part of the processes in the methods of the above embodiments may be implemented by a computer program for instructing relevant hardware, where the program may be stored in a non-volatile computer readable storage medium, and where the program, when executed, may include processes in the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in embodiments provided herein may include non-volatile and/or volatile memory. The nonvolatile memory can include Read Only Memory (ROM), programmable ROM (PROM), electrically Programmable ROM (EPROM), electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double Data Rate SDRAM (DDRSDRAM), enhanced SDRAM (ESDRAM), synchronous link (SYNCHLINK) DRAM (SLDRAM), memory bus (Rambus) direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), among others.
The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The foregoing examples illustrate only a few embodiments of the application and are described in detail herein without thereby limiting the scope of the application. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the application, which are all within the scope of the application. Accordingly, the scope of protection of the present application is to be determined by the appended claims.

Claims (10)

1. A method of measuring a geometric parameter of a left ventricular outflow tract CSEPT, the method comprising:
constructing a left ventricle and mitral valve model;
determining a left ventricular center line and a valgus curve according to the left ventricular and mitral valve model;
Determining CSEPT plane positions according to the left ventricular center line and the involution edge curve;
Determining CSEPT a measurement plane from the CSEPT plane location;
And determining CSEPT parameter measurement values according to the CSEPT measurement planes.
2. The method for measuring geometric parameters of left ventricular outflow tract CSEPT according to claim 1, wherein said constructing left ventricular and mitral valve models specifically comprises:
Acquiring CT images of the end of the isovolumetric shrinkage period;
reconstructing a left ventricle and mitral valve model according to the CT image.
3. The method for measuring geometric parameters of left ventricular outflow tract CSEPT according to claim 1 or 2, wherein said determining left ventricular centerline and coaptation curve from the left ventricular and mitral valve models specifically comprises:
extracting a left ventricular center line in the left ventricular and mitral valve model by taking an aortic valve leaflet aggregation point and a left ventricular apex point as control points;
and extracting a mitral valve involution edge curve from the left ventricle and mitral valve model.
4. A method of measuring geometric parameters of a left ventricular outflow tract CSEPT as defined in claim 3, wherein determining CSEPT a planar position from the left ventricular centerline and the coaptation curve comprises:
B spline interpolation is carried out on the central line of the left ventricle and the mitral valve involution edge curve, and analysis expression of two characteristic curves is obtained;
starting from the apex of the heart apex of the left ventricle, pushing along the direction of the central line of the left ventricle to the aortic valve, wherein the pushing step length is 1/1000 of the total length of the central line of the left ventricle;
And further, obtaining the tangential direction of the point on the central line of the left ventricle according to the B-spline interpolation result, and generating a plane which is perpendicular to the tangential direction and passes through the point, namely a CSEPT plane.
5. The method for measuring geometric parameters of left ventricular outflow tract CSEPT according to claim 4, wherein the B-spline interpolation is performed on the left ventricular centerline and the mitral valve coaptation curve to obtain analytical expressions of two characteristic curves, specifically including:
According to Determining B-spline interpolation results,/>Is a curve, B spline basis/>For node/>Corresponding/>Polynomial of degree/>Representing the highest order of B-spline basis,/>Also known as curve/>Or de Boor point.
6. The method of claim 5, wherein determining CSEPT a measurement plane from the CSEPT plane location, comprises:
determining the shortest distance from the butt-edge curve to the CSEPT plane;
if the shortest distance is smaller than 0.5 unit of propulsion step length, cutting a left ventricle and a mitral valve model by a current plane to obtain a left heart outflow tract section;
If the shortest distance is greater than 0.5 unit of propulsion step length, continuing to propel along the center line of the left ventricle;
Dividing the determined left heart outflow tract section through mitral valve involution edge curve projection;
One side of the section belongs to the outflow channel, is reserved and used for measurement, and is marked as CSEPT measuring plane; the other side of the cross section is below the left atrium, independent of the outflow tract.
7. The method of claim 6, wherein determining CSEPT the measured value of the parameter from the CSEPT measurement plane comprises:
determining CSEPT an area CSEPT-a of the measurement plane;
extracting two intersection points of projection of the involution edge curve on the left chamber outflow channel section and the chamber interval edge, and obtaining the distance between the intersection points by connecting lines, and marking the distance as a long axis L;
the equivalent width CSEPT-L of CSEPT is obtained by dividing the area CSEPT-A of the plane measured by the CSEPT by the long axis L.
8. A device for measuring geometric parameters of a left ventricular outflow tract CSEPT, the device comprising:
the model construction module is used for constructing left ventricle and mitral valve models;
the linear determining module is used for determining a central line of the left ventricle and an involution edge curve according to the left ventricle and mitral valve model;
the plane position determining module is used for determining CSEPT plane positions according to the central line of the left ventricle and the involution edge curve;
A measurement plane determining module for determining CSEPT a measurement plane based on the CSEPT plane position;
and the parameter determining module is used for determining CSEPT parameter measurement values according to the CSEPT measurement planes.
9. A computer device comprising a memory and a processor, the memory storing a computer program that, when executed by the processor, causes the processor to perform the steps of the method of any of claims 1 to 7.
10. A computer readable storage medium storing a computer program which, when executed by a processor, causes the processor to perform the steps of the method of any one of claims 1 to 7.
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