CN113317910A - Mitral annuloplasty system and method of operation thereof - Google Patents
Mitral annuloplasty system and method of operation thereof Download PDFInfo
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- CN113317910A CN113317910A CN202110535550.3A CN202110535550A CN113317910A CN 113317910 A CN113317910 A CN 113317910A CN 202110535550 A CN202110535550 A CN 202110535550A CN 113317910 A CN113317910 A CN 113317910A
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- anchoring
- locking
- wire body
- mitral
- annuloplasty system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
Abstract
The application provides a mitral valve annuloplasty system and an operating method thereof, mainly comprising an anchoring device, a blocking device, a locking device and a separating device, wherein the anchoring device performs anchoring for a posterior valve of a mitral valve to position a wire body on the posterior valve of the mitral valve, the blocking device is used for blocking an atrial septum between a left atrium and a right atrium, the locking device is used for performing positioning and locking operation of the wire body in the right atrium and abuts against one side of the blocking device on the right atrium to maintain a preset distance between the posterior valve of the mitral valve in the left atrium and an anterior valve of the mitral valve; the separation device is used to perform a shearing operation on the wire body in the right atrium. The present application thereby provides a less invasive mitral annuloplasty technique.
Description
Technical Field
The embodiment of the application relates to the technical field of medical instruments, in particular to a mitral valve annuloplasty system and a mitral valve annuloplasty method.
Background
Mitral insufficiency is a valve dysfunction that can lead to blood flow from the left ventricle to the left atrium during systole (during left ventricular contraction) (in a healthy heart, flow from the left ventricle to the left atrium can be prevented by the obstruction of the mitral valve) and can lead to an increase in left atrial pressure, while maintaining normal cardiac output can lead to an increase in left ventricular pressure.
Currently, treatment of patients with MR (mitral insufficiency) or TR (tricuspid insufficiency) may require valve replacement to reduce or eliminate regurgitation. In recent years, the widely accepted treatment has been surgical repair or replacement of the native valve during open heart surgery.
In view of the foregoing, there is a need for a less invasive medical product that can be used to treat mitral valve functional regurgitation.
Disclosure of Invention
In view of the above, the present application provides a mitral annuloplasty system and method of operation thereof to overcome or at least partially solve the above-mentioned problems.
A first aspect of the present application provides a mitral annuloplasty system, comprising: an anchoring device connectable to a wire body for anchoring at least one target anchoring location on a posterior mitral valve in a left atrium, such that the wire body is positioned on the target anchoring location of the posterior mitral valve; the plugging device can be penetrated by the wire body and is used for plugging the interatrial septum between the left atrium and the right atrium; the locking device can be penetrated through the wire body, is used for performing locking operation on the wire body in the right atrium, and abuts against one side, adjacent to the right atrium, of the plugging device so as to enable the mitral valve posterior valve and the mitral valve anterior valve in the left atrium to maintain a preset distance; and a separation device for performing a shearing operation on the wire body within the right atrium.
Optionally, the system includes a delivery sheath having a delivery channel that is sequentially accessible to the left atrium via the inferior vena cava, the right atrium, and the interatrial septum.
Optionally, the anchoring device, the occlusion device, the locking device, and the separation device are respectively movably disposed in the delivery channel of the delivery sheath to reach each target anchoring position in the heart through the delivery sheath.
In a second aspect, the present application provides a method for operating a mitral annuloplasty system, which is applied to the mitral annuloplasty system of the first aspect, and includes: providing a delivery sheath of the mitral annuloplasty system to sequentially enter the left atrium via the inferior vena cava, the right atrium, and the interatrial septum of the heart; providing an anchoring device of the mitral annuloplasty system, connecting a wire body, and entering the left atrium of the heart via the delivery sheath to anchor at least one target anchoring location on a posterior mitral valve in the left atrium, such that the wire body is positioned on the target anchoring location of the posterior mitral valve; providing an occlusion device of the mitral annuloplasty system to penetrate the wire body therein and reach the interatrial septum of the heart by means of the delivery sheath to occlude and position on the interatrial septum; providing a locking device of the mitral annuloplasty system to penetrate the wire body, and reaching the right atrium of the heart by means of the delivery sheath, so as to adjust the positioning position of the wire body relative to the locking device in the right atrium until the posterior mitral valve flap and the anterior mitral valve flap in the left atrium meet a preset separation distance, and providing the locking device to perform a locking operation on the wire body and abut against the occlusion device, so that the preset separation distance is maintained between the posterior mitral valve flap and the anterior mitral valve flap; a separation device providing the mitral annuloplasty system is threaded through the wire body and reaches the right atrium of the heart via the delivery sheath to perform a shearing operation on the wire body within the right atrium.
According to the technical scheme, the mitral valve annuloplasty system and the operation method thereof in the embodiment of the application realize the tightening and shaping of the mitral valve annulus through a drawing mode, can effectively solve the problem of mitral regurgitation, and have the advantages of simple and convenient treatment operation and small invasiveness.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the embodiments of the present application, and other drawings can be obtained by those skilled in the art according to the drawings.
Fig. 1 to 7 show schematic views of different stages of performing mitral annuloplasty by means of a mitral annuloplasty system.
Fig. 8A to 9B and fig. 16A to 16C are schematic structural views showing an anchoring device according to various embodiments of the present application.
Fig. 10A to 10B show schematic structural views of an occlusion device according to an embodiment of the present application.
Fig. 11A to 11B are schematic structural views showing a locking device according to an embodiment of the present application.
Fig. 12A to 13B are schematic structural views showing a separation device according to various embodiments of the present application.
Fig. 14A to 14B show a schematic structural diagram of the line body auxiliary operating instrument including a locking device and a separation device.
Fig. 15 shows an operational diagram of a conventional mitral valve annuloplasty.
Element number
1: a heart;
10: a wire body;
11: the inferior vena cava;
12: the right atrium;
13: the atrial septum;
14: the left atrium;
141: the posterior mitral valve;
142: the anterior mitral valve;
2: an anchoring device;
21: an anchoring device;
211: an anchor;
212: a conduit;
213: a connecting assembly;
2131: a first connecting structure;
2132: a second connecting structure;
22: an anchoring device;
221: a bushing assembly;
2210: a directional channel;
2211: a guide tube;
2212: a guide member;
222: an anchor assembly;
2221: an anchoring hook;
2222: an anchor seat;
23: an anchoring device;
231: a mandrel;
232: an anchoring structure;
233: a sleeve shaft;
234: a clamping structure;
3: a plugging device;
31: a first deformable body;
32: a second deformation body;
33: plugging the channel;
4: a locking device;
41: a first locking member;
42: a second locking member;
43: a conveying member;
44: an auxiliary member;
5: a separation device;
51: a separation device;
511: an outer tube;
5110: an outer tube passage;
5112: a threading structure;
5114: an outer tube distal end;
512: a core tube;
5120: a distal core tube end;
5122: shearing the structure;
52: a separation device;
521: an outer tube;
522: a core tube;
523: a shear assembly;
6: a delivery sheath;
60: a delivery channel;
7: a linear body auxiliary operation instrument;
71: a locking device;
711: a locking structure;
712: a locking control structure;
72: a separation device;
721: shearing the structure;
722: a shear control structure;
8: prosthetic valve rings (prior art);
81: an annulus.
Detailed Description
In order to make those skilled in the art better understand the technical solutions in the embodiments of the present application, the technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, but not all embodiments. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments in the present application shall fall within the scope of the protection of the embodiments in the present application.
As mentioned in the background section above, the normal mitral valve leaflets have coaptation edges and can normally close during systole to prevent blood flow from the left ventricle to the left atrium, while the coaptation edges of a diseased mitral valve annulus (e.g., an enlarged mitral valve annulus) can not normally close during systole, thereby causing regurgitation.
Referring to fig. 15, regarding the valve dysfunction of mitral insufficiency, the present treatment method mainly uses an open chest procedure to implant a prosthetic valve ring 8 with a preset size into the heart 1 of a patient, and sews a diseased valve ring 81 on the prosthetic valve ring 8 to perform an annular tightening operation, so as to achieve the purpose of closing the valve leaflets in the systolic phase. Embodiments of the present disclosure provide a mitral annuloplasty system and a method for operating the same, which can overcome the above-mentioned problems.
The following further describes specific implementations of the embodiments of the present application with reference to the drawings of the embodiments of the present application.
First embodiment
Referring to fig. 1 to 7 in combination, the mitral annuloplasty system according to the first embodiment of the present application is mainly used for performing mitral annuloplasty, and mainly includes an anchoring device 2, an occluding device 3, a locking device 4, and a separating device 5.
Optionally, the mitral annuloplasty system further comprises a delivery sheath 6 having a delivery channel 60, and referring to fig. 1, the delivery sheath 6 may sequentially pass through the inferior vena cava 11 of the heart 1 and sequentially pass through the inferior vena cava 11, the right atrium 12, and the interatrial septum 13 into the left atrium 14.
Wherein, the anchoring device 2, the occluding device 3, the locking device 4 and the separating device 5 of the mitral annuloplasty system are movably inserted into the delivery channel 60 of the delivery sheath 6, respectively, so as to reach each target location (e.g. designated locations in the right atrium 12, interatrial septum 13, left atrium 14) in the heart 1 via the delivery sheath 6.
In this embodiment, the anchoring device 2 may be connected to the wire body 10 for anchoring at least one target anchoring position on the posterior mitral valve 141 in the left atrium 14, so that the wire body 10 is positioned on the target anchoring position of the posterior mitral valve 141.
Alternatively, the anchoring positions of the targets on the posterior mitral valve 141 may be one (refer to fig. 1 to 6) or two (refer to fig. 7), or more than two, and may be adjusted according to actual requirements.
Specifically, the anchoring device 2 may reach the left atrium 14 of the heart 1 via the delivery conduit 60 of the delivery sheath 6 and perform an anchoring operation for a target anchoring position on the posterior mitral valve 141 to position the wire body 10 at the target anchoring position (refer to fig. 1).
Referring to fig. 8A and 8B, in one embodiment, the anchoring device 21 may include an anchor 211, a conduit 212, and a connecting member 213.
Specifically, the connection assembly 213 includes a first connection structure 2131 disposed on the anchor 211 and a second connection structure 2132 disposed on the catheter 212, the second connection structure 2132 is detachably connected to the first connection structure 2131, so as to enable the catheter 212 and the anchor 211 to be in a connection state or a disconnection state, when the catheter 212 and the anchor 211 are in the connection state, the anchor 211 can be controlled by the catheter 212 to perform an anchoring operation on a target anchoring position on the mitral valve posterior flap 141, so as to position the linear body 10 at the target anchoring position, and after the anchoring operation is completed, the first connection structure 2131 and the second connection structure 2132 can be disconnected, so as to remove the second connection structure 2132 and the catheter 212 through the delivery sheath 6, and only the anchor 211 and the first connection structure 2131 are left in the patient (refer to fig. 8B).
Referring to fig. 9A and 9B, in another embodiment, the anchoring device 22 may include a sleeve assembly 221 and an anchoring assembly 222.
Specifically, the sleeve assembly 221 has at least one orientation channel 2210; the anchor assembly 222 is movably disposed through the cannula assembly 221 and has at least one anchor hook 2221. Wherein the anchoring hook 2221 is in the non-anchoring state when located in the sleeve assembly 221, when the anchoring assembly 222 is axially moved relative to the sleeve assembly 221, the anchoring hook 2221 can be made to protrude from the sleeve assembly 221 through the orientation passage 2210 and be directionally bent to be transformed from the non-anchoring state to the anchoring state, so that the anchoring operation is performed on the target anchoring position on the mitral valve posterior flap 141 to position the wire 10 at the target anchoring position, and after the anchoring operation is completed, part of the auxiliary components on the anchoring device 22 can be removed, and only the guide tube 2211 and the guide 2212 of the sleeve assembly 221 and the anchoring hooks 2221 and the anchoring seats 2222 penetrating through the guide tube 2211 and riding on the guide 2212 are detained in the patient (refer to fig. 9B).
Referring to fig. 9A and 9B, in another embodiment, the anchoring device 23 may include a core shaft 231, an anchoring structure 232, a sleeve shaft 233, and a clamping structure 234.
In this embodiment, the anchoring structure 232 is connected to the core shaft 231, the sleeve shaft 233 is movably sleeved on the core shaft 231, and the clamping structure 234 is connected to the sleeve shaft 233.
Wherein, the anchoring structure 232 can be used for anchoring the target tissue, the mandrel 231 can move axially relative to the sleeve shaft 233 to drive the anchoring structure 232 to move from the non-clamping position to the clamping position, and the clamping structure 234 can be switched from the releasing state to the clamping state to clamp the target tissue anchored on the anchoring structure 232.
Specifically, the anchoring structure 232 may be placed in a clamping position and the clamping structure 234 may be placed in a clamping position, and the anchoring device 23 is delivered by means of a delivery system (not shown) in the vicinity of the target tissue to be anchored (for example the heart valve annulus), then, the clamping structure 234 is switched from the clamping state to the releasing state, so that the anchoring structure 232 performs the anchoring operation on the target tissue (refer to the state shown in fig. 16A), and after the anchoring structure 232 anchors the target tissue, the anchoring structure 232 may be moved from the undamped position to the clamped position relative to the clamping structure 234 by moving the mandrel 231 axially relative to the sleeve shaft 233, so as to pull the target tissue between the two clamping arms of the clamping structure 234 by the anchoring structure 232 (refer to the state shown in fig. 16B), and then the clamping structure 234 is switched from the releasing state to the clamping state to clamp the target tissue anchored on the anchoring structure 232 (refer to the state shown in fig. 16C).
The occluding device 3 may be threaded through the wire body 10 and used to occlude an atrial septum 13 between the left atrium 14 and the right atrium 12 (see fig. 1 and 2).
Referring to fig. 10A and 10B, in an embodiment, the blocking device 3 includes a first deformable body 31, a second deformable body 32, and a blocking passage 33 for passing through the wire body 11, wherein, when the first deforming body 31 and the second deforming body 32 are in the contracted state, the whole plugging device 3 can be accommodated in the conveying passage 60 of the conveying sheath 6 for conveying (refer to fig. 10A), when the occluding device 3 is delivered to the atrial septum 13 side of the heart 3 near the left atrium 14, the first deformable body 31 can be expanded and deformed to abut against the atrial septum 13 at the side close to the left atrium 14 (refer to the state shown in fig. 1), and the second deformable body 32 can be expanded and deformed to abut against the atrial septum 13 at the side close to the right atrium 12, so that the atrial septum 13 of the heart 1 is sandwiched between the first deformation body 31 and the second deformation body 32 (refer to the state shown in fig. 2, 10B).
The locking device 4 can be arranged through the wire body 10, and is used for performing a locking operation of the wire body 10 in the right atrium 12, and abuts against one side of the occlusion device 3 adjacent to the right atrium 12, so as to maintain a preset distance between the posterior mitral valve 141 and the anterior mitral valve 142 in the left atrium 14.
In particular, the locking device 4 may reach into the right atrium 12 of the heart 1 via the delivery conduit 60 of the delivery sheath 6 to perform a locking operation on the wire 10 and abut on the occlusion device 3 (refer to fig. 3).
Referring to fig. 11A and 11B, in an embodiment, the locking device 4 may include a first locking member 41, a second locking member 42, a conveying member 43 and an auxiliary member 44; wherein, the first locking member 41 can be axially locked or unlocked with the second locking member 42 and the conveying member 43 respectively; the auxiliary member 44 is detachably connected with the second locking member 42 and is used for assisting the second locking member 42 in positioning along the axial direction; at least one of the first locking member 41 and the second locking member 42 is used for passing through the wire body 10, and the first locking member 41 and the second locking member 42 are axially locked to lock the wire body 10 and abut against the blocking device 3.
Specifically, the separation distance between the anchoring device 2 and the occlusion device 3 can be adjusted by pulling the wire body 10 on the side of the occlusion device 3 located in the right atrium 12, so that the preset separation distance is maintained between the posterior mitral valve 141 and the anterior mitral valve 142 in the left atrium 14 (i.e., the posterior mitral valve 141 and the anterior mitral valve 142 can be closed in the contraction period to prevent regurgitation), and after the adjustment is completed, the locking operation is performed on the wire body 10 by using the locking device 4 (i.e., the first locking member 41 and the second locking member 42) and abutting the side of the occlusion device 3 adjacent to the right atrium 12 (refer to the state shown in fig. 3).
Further, after the locking operation of the wire body 10 is completed, the delivery member 43 and the auxiliary member 44 of the locking device 4 can be detached from the first locking member 41 and the second locking member 42, respectively, and removed via the delivery sheath 6, leaving only the first locking member 41 and the second locking member 42 in the patient.
The separation device 5 is used to perform a shearing operation for the wire 10 within the right atrium 12.
Specifically, the separation device 5 may reach the right atrium 12 of the heart 1 via the delivery conduit 60 of the delivery sheath 6 and perform a shearing operation on the locked wire 10 (refer to fig. 4 to 5).
Referring to fig. 12A and 12B, in an embodiment, the separation device 51 includes an outer tube 511 and a core tube 512, wherein the outer tube 511 includes an outer tube passage 5110 and a threading structure 5112, the outer tube passage 5110 axially penetrates through the outer tube 511, and the threading structure 5112 is disposed at an outer tube distal end 5114 of the outer tube 511 and is used for threading the wire body 10; the core tube 512 is movably disposed through the outer tube passageway 5110 and includes a shear structure 5122 disposed at a distal core tube end 5120 of the core tube 512.
Wherein, the core tube 512 can move axially relative to the outer tube 511 in the direction of the outer tube distal end 51147 to cause the shearing structure 5122 to cut off the wire body 10 threaded through the threading structure 5112 (refer to the state shown in fig. 12B).
Referring to fig. 13A and 13B, in another embodiment, the separating device 52 may include an outer tube 521, a core tube 522 and a shearing assembly 523. The outer tube 521 is used for positioning the wire body 10; the core tube 522 is movably arranged in the outer tube 521 in a penetrating way; the shearing assembly 523 is respectively connected with the outer pipe 521 and the core pipe 522; and the core tube 522 can reciprocate along the axial direction of the outer tube 521, and drives the shearing assembly 523 to switch between the inactive state and the active state, so as to shear the wire 10 positioned on the outer tube 521.
In yet another embodiment, the locking device and the separation device can also be combined to form a linear body auxiliary operating instrument 7 (refer to fig. 14A and 14B).
Specifically, the locking device 71 in the wire body auxiliary operating apparatus 7 can be provided for the wire body 10 to pass through and has a locking structure 711 and a locking control structure 712, and the locking control structure 712 can move back and forth relative to the locking structure 711 to provide movement of the wire body 10 relative to the locking structure 711 or control the locking structure 711 to lock the wire body 10 and abut on the occlusion device 3. Furthermore, the separating device 72 is provided with a cutting structure 721 and a cutting control structure 722, the cutting control structure 722 can move relative to the cutting structure 721 to control the cutting structure 721 to cut the wire 10, and after the cutting operation is completed, the whole separating device 72 can be withdrawn through the conveying sheath 6.
It should be noted that the anchoring device 2, the occlusion device 3, the locking device 4 and the detachment device 5 of the above embodiments are not intended to be limiting, that is, any anchoring device 2, occlusion device 3, locking device 4 and detachment device 5 that can perform an interventional type surgical operation via a catheter (i.e., the delivery sheath 6) can be applied to the present application.
Second embodiment
A second embodiment of the present application provides a method for operating a mitral annuloplasty system, which is applied to the mitral annuloplasty system of the first embodiment, and mainly includes the following steps:
In summary, the mitral valve annuloplasty system and the operating method thereof provided in the embodiments of the present application can achieve tightening and shaping of the mitral valve annulus of the heart by a pulling manner, so that not only is the operation simpler and more convenient, but also the problem of mitral regurgitation can be effectively solved.
In addition, compared with the traditional heart mitral valve annuloplasty, the application has less invasiveness and is beneficial to postoperative recovery of the patient.
Finally, it should be noted that: the above embodiments are only used for illustrating the technical solutions of the embodiments of the present application, and are not limited thereto; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions in the embodiments of the present application.
Claims (12)
1. A mitral annuloplasty system, comprising:
an anchoring device connectable to a wire body for anchoring at least one target anchoring location on a posterior mitral valve in a left atrium, such that the wire body is positioned on the target anchoring location of the posterior mitral valve;
the plugging device can be penetrated by the wire body and is used for plugging the interatrial septum between the left atrium and the right atrium; and
the locking device can be penetrated through the wire body, is used for performing locking operation on the wire body in the right atrium, and abuts against one side, adjacent to the right atrium, of the plugging device so as to enable the mitral valve posterior valve and the mitral valve anterior valve in the left atrium to maintain a preset distance;
a separation device for performing a shearing operation on the wire body within the right atrium.
2. The mitral annuloplasty system of claim 1, wherein the wire body comprises a wire or filament made of a medical polymer material or a metallic material.
3. The mitral annuloplasty system of claim 1, comprising a delivery sheath with a delivery channel that is sequentially accessible to the left atrium via the inferior vena cava, the right atrium, and the interatrial septum.
4. The mitral annuloplasty system of claim 3, wherein the anchoring device, the occluding device, the locking device, and the separating device are each movably disposed through a delivery channel of the delivery sheath to reach target anchoring locations within the heart via the delivery sheath.
5. The mitral annuloplasty system of claim 4, wherein the anchoring device comprises an anchor, a conduit, and a connection assembly; wherein
The connecting assembly comprises a first connecting structure arranged on the anchor and a second connecting structure arranged on the conduit, and the second connecting structure is detachably combined to the first connecting structure so as to enable the conduit and the anchor to be in a connecting state or a disconnecting state.
6. The mitral annuloplasty system of claim 4, wherein the anchoring device comprises a sleeve assembly and an anchoring assembly;
wherein the cannula assembly has at least one orienting channel; the anchoring component is movably arranged in the sleeve component in a penetrating way and is provided with at least one anchoring hook;
and wherein the anchoring hook is in a non-anchoring state when located in the sleeve assembly, the anchoring assembly being axially movable relative to the sleeve assembly such that the anchoring hook protrudes from the sleeve assembly via the orientation channel and is oriented to bend to change from the non-anchoring state to an anchoring state.
7. The mitral annuloplasty system of claim 4, wherein the anchoring device comprises a mandrel, an anchoring structure, a sleeve mandrel, a clamping structure;
the anchoring structure is connected with the mandrel, the sleeve shaft is movably sleeved on the mandrel, and the clamping structure is connected with the sleeve shaft;
the anchoring structure can be used for anchoring target tissue, the mandrel can move axially relative to the sleeve shaft to drive the anchoring structure to move from a non-clamping position to a clamping position, and the clamping structure can be switched from a releasing state to a clamping state to clamp the target tissue anchored on the anchoring structure.
8. The mitral annuloplasty system of claim 4, further comprising a wire assist handling instrument comprising the locking device and the separation device, wherein,
the locking device is provided with a locking structure and a locking control structure, and the locking control structure can reciprocate relative to the locking structure so as to provide the movement of the wire body relative to the locking structure or control the locking structure to lock the wire body and abut against the plugging device;
the separation device is provided with a shearing structure and a shearing control structure, and the shearing control structure can move relative to the shearing control structure to control the shearing structure to shear the wire body.
9. The mitral annuloplasty system of claim 4, wherein the locking device comprises a first locking member, a second locking member, a delivery member, and an auxiliary member; wherein the first locking member is axially lockable and unlockable to the second locking member and the delivery member, respectively; the auxiliary piece is detachably connected with the second locking piece and is used for assisting the second locking piece to be positioned along the axial direction; at least one of the first locking piece and the second locking piece is used for penetrating the wire body, and the first locking piece and the second locking piece are axially locked to lock the wire body and abut against the blocking device; the conveying member and the auxiliary member may be separated from the first locking member and the second locking member, respectively.
10. The mitral annuloplasty system of claim 4, wherein the separation device comprises an outer tube and a core tube; wherein the content of the first and second substances,
the outer tube comprises an outer tube passage and a threading structure, wherein the outer tube passage axially penetrates through the outer tube, and the threading structure is arranged at the far end of the outer tube and is used for threading the wire body; the core tube is movably arranged in the outer tube channel in a penetrating mode and comprises a shearing structure arranged at the far end of the core tube;
and the core tube can axially move relative to the outer tube in the direction of the far end of the outer tube, so that the shearing structure cuts off the line body penetrating through the threading structure.
11. The mitral annuloplasty system of claim 4, wherein the separation device comprises an outer tube, a core tube, and a shear assembly; wherein the content of the first and second substances,
the outer tube is used for positioning the wire body; the core pipe is movably arranged in the outer pipe in a penetrating way; the shearing assembly is connected with the outer pipe and the core pipe;
and the core pipe can reciprocate along the axial direction of the outer pipe and drive the shearing assembly to switch between a non-acting state and an acting state so as to shear the line body.
12. A method of operating a mitral annuloplasty system, applied to the mitral annuloplasty system of claims 1 to 11, the method comprising:
providing a delivery sheath of the mitral annuloplasty system to sequentially enter the left atrium via the inferior vena cava, the right atrium, and the interatrial septum of the heart;
providing an anchoring device of the mitral annuloplasty system, connecting a wire body, and entering the left atrium of the heart via the delivery sheath to anchor at least one target anchoring location on a posterior mitral valve in the left atrium, such that the wire body is positioned on the target anchoring location of the posterior mitral valve;
providing an occlusion device of the mitral annuloplasty system to penetrate the wire body therein and reach the interatrial septum of the heart by means of the delivery sheath to occlude and position on the interatrial septum;
providing a locking device of the mitral annuloplasty system to penetrate the wire body, and reaching the right atrium of the heart by means of the delivery sheath, so as to adjust the positioning position of the wire body relative to the locking device in the right atrium until the posterior mitral valve flap and the anterior mitral valve flap in the left atrium meet a preset separation distance, and providing the locking device to perform a locking operation on the wire body and abut against the occlusion device, so that the preset separation distance is maintained between the posterior mitral valve flap and the anterior mitral valve flap;
a separation device providing the mitral annuloplasty system is threaded through the wire body and reaches the right atrium of the heart via the delivery sheath to perform a shearing operation on the wire body within the right atrium.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110535550.3A CN113317910A (en) | 2021-05-17 | 2021-05-17 | Mitral annuloplasty system and method of operation thereof |
| PCT/CN2021/136127 WO2022242117A1 (en) | 2021-05-17 | 2021-12-07 | Mitral valve annuloplasty system and operation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110535550.3A CN113317910A (en) | 2021-05-17 | 2021-05-17 | Mitral annuloplasty system and method of operation thereof |
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| Publication Number | Publication Date |
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| CN113317910A true CN113317910A (en) | 2021-08-31 |
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| CN202110535550.3A Pending CN113317910A (en) | 2021-05-17 | 2021-05-17 | Mitral annuloplasty system and method of operation thereof |
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| Country | Link |
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| CN (1) | CN113317910A (en) |
| WO (1) | WO2022242117A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114145885A (en) * | 2021-12-06 | 2022-03-08 | 上海汇禾医疗科技有限公司 | Integrated medical instrument |
| WO2022242117A1 (en) * | 2021-05-17 | 2022-11-24 | 上海汇禾医疗科技有限公司 | Mitral valve annuloplasty system and operation method thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090069885A1 (en) * | 2004-05-14 | 2009-03-12 | Rahdert David A | Devices, systems, and methods for reshaping a heart valve annulus |
| WO2011047168A1 (en) * | 2009-10-14 | 2011-04-21 | Cardiovascular Technologies, Llc | Percutaneous transvalvular intraannular band for mitral valve repair |
| CN106573129B (en) * | 2014-06-19 | 2019-09-24 | 4科技有限公司 | Heart tissue is tightened |
| US20170340443A1 (en) * | 2016-05-24 | 2017-11-30 | Edwards Lifesciences Corporation | Posterior mitral valve leaflet approximation |
| CN109846579B (en) * | 2018-11-04 | 2024-03-15 | 上海汇禾医疗科技股份有限公司 | Clamp, valve annulus clamp assembly, valve annulus repair system and use method |
| CN109498216A (en) * | 2018-12-25 | 2019-03-22 | 乐普（北京）医疗器械股份有限公司 | A kind of drag wire locking catheters for valve reparation |
| WO2020236417A1 (en) * | 2019-05-22 | 2020-11-26 | Edwards Lifesciences Corporation | Expandable anchor for heart valve repair devices |
| WO2021003375A1 (en) * | 2019-07-03 | 2021-01-07 | Boston Scientific Scimed, Inc. | Devices, systems, and methods for anchoring an artificial chordae tendineae to a papillary muscle or heart wall |
| CN112294376B (en) * | 2019-08-29 | 2021-12-28 | 杭州德晋医疗科技有限公司 | A long-range suture locking device of staple and intervention formula for locking suture |
| CN113317910A (en) * | 2021-05-17 | 2021-08-31 | 上海汇禾医疗科技有限公司 | Mitral annuloplasty system and method of operation thereof |
-
2021
- 2021-05-17 CN CN202110535550.3A patent/CN113317910A/en active Pending
- 2021-12-07 WO PCT/CN2021/136127 patent/WO2022242117A1/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022242117A1 (en) * | 2021-05-17 | 2022-11-24 | 上海汇禾医疗科技有限公司 | Mitral valve annuloplasty system and operation method thereof |
| CN114145885A (en) * | 2021-12-06 | 2022-03-08 | 上海汇禾医疗科技有限公司 | Integrated medical instrument |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022242117A1 (en) | 2022-11-24 |
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