CN109498216A - A kind of drag wire locking catheters for valve reparation - Google Patents
A kind of drag wire locking catheters for valve reparation Download PDFInfo
- Publication number
- CN109498216A CN109498216A CN201811587246.8A CN201811587246A CN109498216A CN 109498216 A CN109498216 A CN 109498216A CN 201811587246 A CN201811587246 A CN 201811587246A CN 109498216 A CN109498216 A CN 109498216A
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- CN
- China
- Prior art keywords
- drag wire
- locking
- sheath
- locking device
- valve reparation
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- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
- A61F2/2457—Chordae tendineae prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2466—Delivery devices therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3413—Needle locating or guiding means guided by ultrasound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2063—Acoustic tracking systems, e.g. using ultrasound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2065—Tracking using image or pattern recognition
Abstract
The invention discloses a kind of drag wire locking catheters for mitral valve repair, mainly to mitral regurgitation lesion, are adjusted and are locked in real time under ultrasound or radiography to being implanted into after drag wire after annulus expansion and rupture of chordae tendinca, and can be realized completely reversibility operation；The invention can simplify the operation of patient, have good therapeutic effect to mitral regurgitation.
Description
Technical field
The invention belongs to the field of medical instrument technology, in particular to a kind of drag wire locking catheters for valve reparation.
Background technique
With the development of society and the aging of population, the hair of mitral regurgitation (mitral regurgitation, MR)
Sick rate is in the situation obviously risen, has become a kind of common heart valve disease at present.According to pathogenesis, MR can be divided into
Primary (organic, 30%) and secondary (functional, 70%),.According to the state of an illness, MR can be divided into acute and chronic.Slightly
MR clinical symptoms can not occur within some time, and prognosis is preferable.Severe MR can produce the symptoms such as palpitaition, uncomfortable in chest, out of breath.It is anxious
Property severe MR patient tolerability it is very poor, it is easy to occur dead.Chronic severe MR, in asymptomatic person 5 years cardiovascular death and
Cardiovascular event incidence is 14 ± 3% and 333 ± 3%, and person (the New York Heart association (NYHA) that occurs severe heart failure
3 grades of cardiac functional grading or more) every annual death rate is up to can 34%.
In mitral regurgitation, mitral regurgitation interventional therapeutic technique can be divided into two classes: one kind is through conduit bicuspid valve
Prosthetic, such as MitraClip, PASCAL, ValveClam, Cardioband, Mitralign, NeoChord, it is another kind of to be
Through conduit bicuspid valve implantation, at present using prosthetic as essential therapeutic arsenals, but there is also a little problems for technology at present, such as
Big single hole is become small diplopore by leaflet before and after clamping bicuspid valve by MitralClip, achievees the purpose that treatment, but be implanted into
Path is too far, and operation is excessively complicated, and there are also to be improved.Two points are completed by the operation method of heart beating and device at present
The reparation of valve becomes the direction treated from now on, can be by being implanted into people for prolapsus situation when carrying out mitral valve reparation
The leaflet of prolapsus is fixed in work chordae tendineae, and annulus expansion lesion can be anchored respectively in anterior mitral valve and back lobe, passed through
Shorten the spacing of preceding valve and back lobe to reduce reflux, needs a kind of drag wire locking catheters in this case, it can be in real time super
The length of the drag wire of implantation is measured and adjusted under sound or radiography, to achieve the purpose that treat reflux.
To solve the above-mentioned problems, the present invention provides a kind of drag wire locking catheters for valve reparation.The conduit
Drag wire can be adjusted and be locked in real time by way of minimally invasive intervention, and being capable of completely reversibility operation.The device
Feature is to complete to perform the operation in heart beating, which can be quasi- by the function of modern image documentation equipment such as three-D ultrasonic, radiography
The really drawing line length of control implantation.The conduit shortens operating time, reduces wound degree, reduces operating difficulty and operation
Risk.
Summary of the invention
The object of the present invention is to provide one kind by treating through intubation intervention mode because mitral annulus expansion and chordae tendineae are disconnected
Mitral valve prolapse caused by splitting and the drag wire locking catheters for causing mitral regurgitation.
Drag wire locking catheters proposed by the present invention for valve reparation can be with when carrying out mitral valve reparation
Entered in vivo by minimally invasive intervening mode, prolapsus lesion can be consolidated by leaflet of the implantable artificial chordae tendineae to prolapsus
It is fixed, annulus expansion lesion can be anchored respectively in anterior mitral valve and back lobe, subtracted by the spacing of valve and back lobe before shortening
Small reflux needs a kind of drag wire locking catheters in this case, can measure under ultrasound or radiography in real time and adjustment is implanted into
Drag wire length, come achieve the effect that treat reflux.
In order to reach the goals above, the present invention provides a kind of drag wire locking catheters for valve reparation, features
Include: the locking catheters include for the outer sheath 15 of fixed control locking device release and cutting drag wire, be located at it is described outer
The hanging head sheath 25 of fixedly locked device in sheath, is located at the hanging head sheath at the swingle 24 on the inside of hanging head sheath
The locking device 2 of distal end, the handle 1 for being used to operate positioned at the outer sheath proximal end.
It is preferred that the outer sheath head end has L shape opening, and there are cutting edge at side, L-type opening is used to place drawing
Line rotates by a certain angle outer sheath when needing to cut off drag wire, and the cutting edge is rotated to drawing line position to cut off.
It is preferred that the outer sheath head end is made of metal material, there is stronger torsion to control performance.
It is preferred that the hanging head sheath head end has fixed hanging head, hanging head can be 2 or 3.
It is preferred that the hanging head sheath head end is made of niti material, and pre-setting facilitates locking device to disengage at " V " type.
It is preferred that the swingle is made of metal material, there is stronger torsion to control performance.
It is preferred that the locking device is made of Nitinol, high molecular material.
It is preferred that the plug that is screwed in the locking device has reversible operation by threads turn.
It is preferred that the locking device body lumen has protrusion, can play the role of increasing friction fit power.
It is preferred that the locking device tail end cover and the plug that is screwed.
The advantages of system of the invention is that minimally invasive intervention operation can be realized under heart beating, by atrial septal puncture into
Enter atrium dextrum and right ventricle, implantation after annulus expansion and rupture of chordae tendinca is pulled using locking device under three-D ultrasonic and radiography
The length of adjustment drag wire in real time is carried out after line, while cutting off drag wire, the operation of patient is simplified, to reach treatment bicuspid valve
The function of reflux.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described.It should be evident that the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the proximal handle figure of the drag wire locking catheters for valve reparation；
Fig. 2 is the locking device optical cable of the drag wire locking catheters for valve reparation；
Fig. 3 is the locking device original state figure of the drag wire locking catheters for valve reparation；
Fig. 4 is the locking device locking state figure of the drag wire locking catheters for valve reparation；
Fig. 5 is the locking device main body figure of the drag wire locking catheters for valve reparation；
Fig. 6 is the tail end cover figure of the drag wire locking catheters for valve reparation；
Fig. 7 is the plug figure that is screwed of the drag wire locking catheters for valve reparation；
Fig. 8 is the swingle figure of the drag wire locking catheters for valve reparation；
Fig. 9 is the outer sheath figure of the drag wire locking catheters for valve reparation；
Figure 10 is the outer sheath operation step map of the drag wire locking catheters for valve reparation；
Figure 11 is the schematic diagram through conduit artificial cords implantation；
Figure 12 is the schematic diagram through conduit annulus reduction surgery；
Label in attached drawing is as follows: 1. handle, 2. locking device, 3. drag wire, 4. apex of the heart anchor, 5. leaflet 6. conveys sheath
7. deadman of pipe, 11. tail end revolving part, 12. main body 13. pulls 14. epitheca tube socket of button, 15. outer sheath 21. locking dress
It sets main body 22. and is screwed and fill in 23. tail end cover, 24. swingle, 25. hanging head sheath, 151. cutting edge 152.L shape notch
211. 241. square section of raised 212. hanging groove, 213. side opening, 221. inner hole, 222. boss, 242. triangular-section
243. rectangular section
Specific embodiment
See Fig. 1, Fig. 2, referring to 3 and Fig. 4, the present invention provides a kind of drag wire lockings for valve reparation to lead for cooperation
Pipe, the locking catheters include for the outer sheath 15 of fixed control locking device release and cutting drag wire, are located at the epitheca
The hanging head sheath 25 of fixedly locked device in pipe, the swingle 24 on the inside of hanging head sheath, be located at the hanging head sheath it is remote
The locking device 2 at end, the handle 1 for being used to operate positioned at the outer sheath proximal end.
The handle 1 include main body 12, tail end revolving part 11, pull button 13, epitheca tube socket 14, wherein epitheca tube socket 14 with
Outer sheath 15 is connected, and can be moved forward and backward and rotate on handle, and tail end revolving part is connected with swingle 24, can control rotation
The rotation of bull stick 24, hanging head sheath 25 are connected with main body 12, pull button 13 and drag wire 3, can move left and right to control drawing
The position of line.
The locking device 2 includes locking device main body 21, and be screwed plug 22, tail end cover 23, swingle 24, hanging head
Sheath 25, wherein locking device main body 21 is connected with hanging head sheath 25 by hanging head, and locking device main body 21 and tail end cover 23 can
It is fixed by welding manner, be screwed plug 22 and tail end cover 23 are controlled by rotation tail end revolving part 11 by being threadedly engaged
Swingle 24 processed, and then control the position for the plug 22 that is screwed.
The original state of system is as shown in figure 3, drag wire 3 passes through the inner hole and side opening 213 of 21 head end of locking device main body
Draw, along drag wire 3 by drag wire locking catheters be pushed to want fixation position after, by rotation tail end revolving part 11 come
Swingle 24 is controlled, and then it is mobile to 21 head end of locking device main body to control the plug 22 that is screwed, and then fixes drag wire.
There is protrusion 211 in the locking device main body 21, play the frictional force increased between drag wire and locking device,
The locking device main body 21 has hanging groove 212, and hanging groove 212 is connected with the distal end of hanging head sheath 225, the number of hanging groove
Amount can be 2 or 3, preferably 2.
It is described be screwed plug 22 and tail end cover 23 by internal and external threads be cooperatively connected, be screwed fill in 22 head ends have
One boss 222, outer diameter are larger than the internal diameter of tail end cover 23, fill in 22 from tail end cover 23 to prevent from being screwed
Middle disengaging, plays the role of limit.
24 head end of swingle has different shapes, cooperates with the inner hole 221 for the plug 22 that is screwed, cross section can
To be facing 241, gore 242 can also be, rectangular surfaces 243, for transmitting torque, the plug 22 that will be screwed is rotated to
Designated position, as shown in Figure 8.
As shown in Figures 9 and 10, head end is L-shaped groove mouth 152, for accommodating drag wire 3, L-type slot for 15 distal end of outer sheath
The one side mill of mouth 152 has cutting edge 151, after completing locking, rotates outer sheath 15, makes the cutting drag wire 3 of cutting edge 151, completes to cut
After disconnected step, outer sheath 15 of dropping back separates hanging head sheath 25 and locking device hanging groove 212.
Invention is further described in detail with reference to the accompanying drawings and examples, but implementation of the invention is not limited only to
This.
Embodiment 1
See that Fig. 1,2,4,10,11, Figure 11 are the schematic diagram through conduit artificial cords implantation.
Artificial cords 3 and apex of the heart anchor 4 are implanted by delivery sheath 6 first, wherein artificial cords 3 are fixed on prolapsus
Leaflet 5 at, apex of the heart anchor 4 is fixed between papillary muscle, is at this moment needed apex of the heart anchor 4 and artificial tendon through drag wire locking catheters
Rope connects, and artificial cords here are drag wire 3, and concrete operations are as follows: first along drag wire 3 and apex of the heart anchor 4
Drag wire locking catheters are sent near apex of the heart anchor 4 by connecting line, then pass through drawing button 13 under the guidance of ultrasound or radiography
Drag wire 3 is pulled, when judging that drag wire 3 is of convenient length, the tail end revolving part of rotating handle 1, will be screwed 22 rotation of plug
To locking state, as shown in figure 4, repeating aforesaid operations after can inversely discharging if 3 length of drag wire is improper, led in determination
After bracing wire 3 is of convenient length, the epitheca tube socket 14 of rotating handle 1 cuts off drag wire, continues to rotate epitheca tube socket 14, makes hanging head
25 head end of sheath is withdrawn from from 15 head end of outer sheath, is finally completed the separation of hanging head sheath 25 and locking device 2, is synchronously completed
The locking and rupturing operation of drag wire 3.The conduit simplifies the operation of patient, can lock and cut off simultaneously drag wire, shortens
Operating time reduces wound degree, reduces operating difficulty and operation risk.
Embodiment 2
See that Fig. 1,2,4,10,12, Figure 12 are the schematic diagram through conduit annulus reduction surgery.
In order to shorten the distance of anterior mitral valve and back lobe, deadman 7 is implanted into respectively by delivery sheath 6 first
In bicuspid valve back lobe middle position and atrial septum position, 3 one end of drag wire is fixed on back lobe deadman, and the other end is from atrial septum
It is pierced by deadman, the concrete operations of drag wire locking catheters are as follows: being sent into drag wire locking catheters first along drag wire 3
To near apex of the heart anchor 4, then by the drawing drawing of button 13 drawing 3 under the guidance of ultrasound or radiography, when judging 3 length of drag wire
When suitable, the tail end revolving part of rotating handle 1, the plug 22 that will be screwed rotates to locking state, as shown in figure 4, if drawing
3 length of line is improper, and aforesaid operations are repeated after can inversely discharging, after determining that drag wire 3 is of convenient length, outside rotating handle 1
Sheath tube socket 14, drag wire is cut off, and is continued to rotate epitheca tube socket 14, is removed 25 head end of hanging head sheath from 15 head end of outer sheath
Out, it is finally completed the separation of hanging head sheath 25 and locking device 2, synchronously completes the locking and rupturing operation of drag wire 3.The conduit
The operation of patient is simplified, drag wire can be locked and cut off simultaneously, shortens operating time, wound degree is reduced, reduces
Operating difficulty and operation risk.
The preferred embodiment of the present invention has been described in detail above, but the invention be not limited to it is described
Embodiment, those skilled in the art can also make various equivalent on the premise of not violating the inventive spirit of the present invention
Variation or replacement, these equivalent variation or replacement are all included in the scope defined by the claims of the present application.
Claims (7)
1. being used for the drag wire locking catheters of valve reparation, which is characterized in that the locking catheters include for fixed control locking
The outer sheath 15 of device release and cutting drag wire, the hanging head sheath 25 of fixedly locked device in the outer sheath, position
Swingle 24 on the inside of hanging head sheath, positioned at hanging head sheath distal end locking device 2, be located at the outer sheath proximal end and use
Come the handle 1 operated.
2. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the outer sheath 15
Cooperate with hanging head sheath 25, the release of locking device can be controlled.
3. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the outer sheath 15
Head end is L-shaped groove mouth 152, and for accommodating drag wire 3, the one side mill of L-type notch 152 has cutting edge 151, can cut off drag wire 3,
Realization cutting and release operation can be synchronized.
4. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the hanging head sheath
25 can be connected with locking device 2 by hanging head, guarantee that relative motion does not occur for locking device.
5. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the locking device
2 are capable of fixing drag wire, and being capable of invertible operation.
6. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the locking device
The matching surface of main body 21 has bulge-structure, plays the role of increasing friction fit power between locking device 2 and drag wire 3.
7. the drag wire locking catheters according to claim 1 for valve reparation, which is characterized in that the rotation head
24 ends are triangle, rectangle, square, star, but are not limited to these shapes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811587246.8A CN109498216A (en) | 2018-12-25 | 2018-12-25 | A kind of drag wire locking catheters for valve reparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811587246.8A CN109498216A (en) | 2018-12-25 | 2018-12-25 | A kind of drag wire locking catheters for valve reparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109498216A true CN109498216A (en) | 2019-03-22 |
Family
ID=65755131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811587246.8A Pending CN109498216A (en) | 2018-12-25 | 2018-12-25 | A kind of drag wire locking catheters for valve reparation |
Country Status (1)
| Country | Link |
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| CN (1) | CN109498216A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10945718B2 (en) | 2014-09-17 | 2021-03-16 | Cardiomech As | Device for heart repair |
| WO2021129006A1 (en) * | 2019-12-25 | 2021-07-01 | 杭州德晋医疗科技有限公司 | Transcatheter suture line implantation device and transcatheter chordae tendineae implantation system |
| WO2021135270A1 (en) * | 2019-12-31 | 2021-07-08 | 杭州德晋医疗科技有限公司 | Integrated anchor and anchoring system |
| WO2021135347A1 (en) * | 2019-12-31 | 2021-07-08 | 杭州德晋医疗科技有限公司 | Anchor delivery device and artificial-tendon implant apparatus |
| US11147673B2 (en) | 2018-05-22 | 2021-10-19 | Boston Scientific Scimed, Inc. | Percutaneous papillary muscle relocation |
| WO2021238034A1 (en) * | 2020-05-29 | 2021-12-02 | 迈特锐吉(北京)医疗科技有限公司 | Suture locking device and suture locking device implanting apparatus |
| CN113749823A (en) * | 2021-10-12 | 2021-12-07 | 科凯(南通)生命科学有限公司 | Mitral valve repair clamp connected with conveying structure in clamping manner |
| CN114767341A (en) * | 2022-06-20 | 2022-07-22 | 乐普（北京）医疗器械股份有限公司 | Implant locking structure |
| CN114886612A (en) * | 2022-05-06 | 2022-08-12 | 上海以心医疗器械有限公司 | Thread locking device and thread locking device |
| WO2022241755A1 (en) * | 2021-05-21 | 2022-11-24 | 上海形状记忆合金材料有限公司 | Ring contraction apparatus for mitral valve annulus |
| WO2022242117A1 (en) * | 2021-05-17 | 2022-11-24 | 上海汇禾医疗科技有限公司 | Mitral valve annuloplasty system and operation method thereof |
| CN116531148A (en) * | 2023-07-05 | 2023-08-04 | 科瑞迈吉(北京)医疗科技有限公司 | A lockwire system for valve repair operation |
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Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10945718B2 (en) | 2014-09-17 | 2021-03-16 | Cardiomech As | Device for heart repair |
| US11253247B2 (en) | 2014-09-17 | 2022-02-22 | Cardiomech As | Device for heart repair |
| US11147673B2 (en) | 2018-05-22 | 2021-10-19 | Boston Scientific Scimed, Inc. | Percutaneous papillary muscle relocation |
| US11678988B2 (en) | 2018-05-22 | 2023-06-20 | Boston Scientific Scimed, Inc. | Percutaneous papillary muscle relocation |
| WO2021129006A1 (en) * | 2019-12-25 | 2021-07-01 | 杭州德晋医疗科技有限公司 | Transcatheter suture line implantation device and transcatheter chordae tendineae implantation system |
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| WO2021135347A1 (en) * | 2019-12-31 | 2021-07-08 | 杭州德晋医疗科技有限公司 | Anchor delivery device and artificial-tendon implant apparatus |
| WO2021238034A1 (en) * | 2020-05-29 | 2021-12-02 | 迈特锐吉(北京)医疗科技有限公司 | Suture locking device and suture locking device implanting apparatus |
| WO2022242117A1 (en) * | 2021-05-17 | 2022-11-24 | 上海汇禾医疗科技有限公司 | Mitral valve annuloplasty system and operation method thereof |
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| CN113749823B (en) * | 2021-10-12 | 2023-06-27 | 科凯(南通)生命科学有限公司 | Mitral valve repair clamp connected with conveying structure in clamping mode |
| CN114886612A (en) * | 2022-05-06 | 2022-08-12 | 上海以心医疗器械有限公司 | Thread locking device and thread locking device |
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