CN117959607A - Ultraviolet irradiation treatment equipment and use method - Google Patents
Ultraviolet irradiation treatment equipment and use method Download PDFInfo
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- CN117959607A CN117959607A CN202311339770.4A CN202311339770A CN117959607A CN 117959607 A CN117959607 A CN 117959607A CN 202311339770 A CN202311339770 A CN 202311339770A CN 117959607 A CN117959607 A CN 117959607A
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Abstract
The invention discloses ultraviolet irradiation treatment equipment and a using method thereof, and relates to the technical field of ultraviolet sterilization; the device comprises a main body, wherein a driving part is fixedly arranged on the main body, a treatment part is further arranged on the main body, the treatment part is arranged on the driving part, and a control panel for controlling the treatment part is further arranged on the main body; the treatment component comprises an ultraviolet laser emitter for emitting ultraviolet laser; the ultraviolet irradiation treatment equipment and the use method for the equipment are clear and perfect, the accuracy and the treatment efficiency of the equipment can be greatly improved, the virus property can be accurately obtained through the characteristic frequency, the treatment wavelength is determined, clear shape and area determination is carried out on a focus area through the photographic technology, the damage of ultraviolet rays to normal cells during treatment is minimum, and the treatment effect is excellent.
Description
Technical Field
The invention relates to the technical field of ultraviolet sterilization, in particular to ultraviolet irradiation treatment equipment and a using method thereof.
Background
The ultraviolet disinfection technology is often used for video convenient disinfection of meat at the present stage, the commonly used short wave deep ultraviolet light can effectively inactivate bacteria and viruses harmful to human bodies, has quite high-efficiency disinfection and disinfection capability, but is seldom applied to clinical treatment because various diseases such as skin cancer, eye inflammation and the like are easily caused by long-time irradiation of human skin and eyes, and along with continuous exploration of medical experiments, the ultraviolet light with the wavelength of 240-280nm is found to have high-efficiency disinfection effect in pathological experiments, but the wavelength needs to be adjusted to avoid the damage of the ultraviolet light to normal cells of the human bodies, although the conventional treatment equipment has simple irradiation function, the systemization is not perfect enough, and the condition that the treatment effect is not good or the human bodies are always damaged to a certain extent is usually generated.
Disclosure of Invention
The invention aims to solve the technical problems of imperfect and irregular use of the existing ultraviolet radiation treatment equipment.
The invention is realized by the following technical scheme.
The invention discloses ultraviolet irradiation treatment equipment, which comprises a main body, wherein a driving part is fixedly arranged on the main body, a treatment part is further arranged on the main body, the treatment part is arranged on the driving part, and a control panel for controlling the treatment part is further arranged on the main body;
The treatment component comprises an ultraviolet laser emitter for emitting ultraviolet laser;
The ultraviolet laser wavelength controller is used for controlling the power of ultraviolet laser;
An ultraviolet emission caliber adjusting device for adjusting the diameter of the optical emission wave;
The optical collimator is used for mutually parallel emitted ultraviolet lasers;
an ultraviolet light emission gun; for directing an ultraviolet laser to the focal location.
Further, the ultraviolet laser wavelength controller emits an ultraviolet laser wavelength of 260.+ -.5 nm.
Further, the ultraviolet laser transmitter controls the emitted ultraviolet laser at 25 watts.
Also discloses a using method of the ultraviolet irradiation treatment equipment, which comprises the following steps:
s01, determining virus characteristic frequency;
S02, laser tuning;
S03, focus positioning;
S04, adjusting parameters of the treatment equipment;
S05, carrying out irradiation treatment, and monitoring and feeding back in real time.
Further, in the step S01, the characteristic frequency of the target virus is accurately determined using a spectroscopic analysis technique.
Further, in the step S02, the proper laser wavelength is selected to tune according to the characteristic frequency of the virus determined in the step S01.
Further, in the above step S03, the focus position is precisely determined by the imaging technique.
Further, in the step S05, the effect of the laser processing is determined by using a real-time detection technique, and the effect is fed back to the treatment device to adjust the laser parameters in real time.
Further, the body at the focal site is covered with a layer of transparent carrier material for increasing the penetration of the ultraviolet laser light.
The invention has the beneficial effects that: the ultraviolet irradiation treatment equipment provided by the invention can achieve the aim of treating the virus cells clearly through ultraviolet rays by adjusting and controlling the wavelength, irradiation time and ultraviolet intensity of the ultraviolet rays, has a collimation function and a light caliber adjusting function, is more specific to ultraviolet ray control, can greatly improve the accuracy and treatment efficiency of the equipment by definitely perfecting the use method of the equipment, can accurately obtain the virus property through the characteristic frequency, determines the treatment wavelength, and also can determine the definitely shape and area of a focus area through the irradiation technology, so that the damage of the ultraviolet rays to normal cells during treatment is minimum, and has an excellent treatment effect.
Drawings
In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are used in the description of the embodiments or the prior art will be briefly described, it being obvious that the drawings in the description below are only some embodiments of the invention, and that other drawings can be obtained from these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of an embodiment of the present invention;
Fig. 2 is a flow chart of the method of the present invention.
Detailed Description
The invention will now be described in detail with reference to fig. 1-2, wherein for convenience of description, the orientations described below are now defined as follows: the vertical, horizontal, front-rear directions described below are identical to the vertical, horizontal, front-rear directions of the projection relationship of fig. 1 itself.
1-2, An ultraviolet irradiation treatment apparatus comprises a main body 10, wherein a driving part 13 is fixedly arranged on the main body 10, a treatment part 12 is further arranged on the main body 10, the treatment part is arranged on the driving part 13, and a control panel 11 for controlling the treatment part 12 is further arranged on the main body 10;
the treatment member 12 includes an ultraviolet laser emitter 15 for emitting ultraviolet laser light;
An ultraviolet laser wavelength controller 14 for controlling the power of the ultraviolet laser;
an ultraviolet emission caliber adjusting device 16 for adjusting the diameter of the optical emission wave;
an optical collimator 17 for emitting ultraviolet laser light parallel to each other;
An ultraviolet light emission gun 18; for directing an ultraviolet laser to the focal location.
The ultraviolet laser wavelength controller 14 emits ultraviolet laser light having a wavelength of 260.+ -.5 nm, preferably 260nm.
The ultraviolet laser transmitter 15 controls the emitted ultraviolet laser light to 25 watts.
The ultraviolet laser wavelength controller 14 is used for controlling the laser emitter 15 to emit the required wavelength through laser tuning, and medical staff can control the wavelength requirement of the ultraviolet laser wavelength controller 14 through the control panel 11, control the light intensity and duration of the ultraviolet laser emitter 15, and control the ultraviolet emission caliber adjusting device 16 to change the light emitted by the laser emitter into the caliber required for treatment.
The optical collimator 17 can perform horizontal calibration on light emitted by the laser emitter, and the ultraviolet laser processed by the optical collimator has good positive significance in penetration of the ultraviolet laser and comparison setting of the ultraviolet laser and a patient area, so that the influence of light on normal cells can be reduced.
The driving part 13 can drive the treatment part 12 to circularly move so as to achieve the required movement of the treatment part 12, and the treatment part 12 can increase the irradiation area through circular swinging.
The main body 10 is placed on a movable table 19 to facilitate movement.
Also discloses a method for using the ultraviolet irradiation treatment equipment, which comprises the following steps:
s01, determining virus characteristic frequency;
S02, laser tuning;
S03, focus positioning;
S04, adjusting parameters of the treatment equipment;
S05, carrying out irradiation treatment, and monitoring and feeding back in real time.
In the above step S01, the characteristic frequency of the target virus is accurately determined using a spectroscopic analysis technique. The precondition of treating the patient is to determine that the patient is infected with the virus and to clarify the etiology and pathology, so that the characteristic frequency of the target virus needs to be accurately determined first. By using spectroscopic analysis techniques such as raman spectroscopy, fourier transform infrared spectroscopy, etc.
The laser Raman spectroscopy has better application in organic chemistry, polymer, biology and surface and film, belongs to a mature spectrum analysis technology, is a powerful means for researching biological macromolecules, and can research the structures and changes of the biological macromolecules in a near natural state and an active state due to the fact that the Raman spectroscopy of water is weak and the spectrogram is simple. Raman spectroscopy has been important in clinical medicine in the research of secondary structures of proteins, the action between DNA and carcinogen molecules, structural changes of rhodopsin in light circulation, calcification deposition in arteriosclerosis operation, erythrocyte membranes, and other medical demands.
In the step S02, the characteristic frequency of the virus is determined according to the step S01, the proper laser wavelength is selected for tuning, the characteristic spectrum of the virus is obtained through the spectrum analysis technology, the virus property can be clearly known, the ultraviolet laser wavelength with a better treatment effect on the virus is determined according to the virus property, and the laser is tuned to stably emit the ultraviolet laser with the required wavelength.
The laser tuning is to select the proper laser wavelength to tune according to the characteristic frequency of the virus. This can be achieved by using a laser source, such as a Continuous Wave (CW) laser or a pulsed laser, and by adjusting the frequency or wavelength of the laser light.
In the step S03, the focal position is precisely determined by using an imaging technique, and the focal region is precisely located by using an imaging technique (such as MRI, CT, etc.), so as to ensure precise irradiation of laser, and by scanning by using imaging devices in the modes of CT, MRI, etc., a doctor can clean and determine the position, shape, and area of the focal according to the scan slice.
In the step S04, the parameters of the treatment device are adjusted, mainly including the wavelength determined by laser tuning in the step S02 by using a laser, controlling the power of the laser, determining the duration of irradiation of the ultraviolet laser, further adjusting the light emitting shape of the laser of the treatment device according to the shape of the focus, so that the irradiation shape of the laser is consistent with the shape of the focus, or the irradiation shape of the laser is approximately consistent with the shape of the focus, or the ultraviolet light emitting gun of the treatment device is added with an automatic circulation movement function, so that the treated ultraviolet laser can circulate at the position of the focus, ensuring that only the virus is damaged, and normal cells are not affected or the influence on the normal cells is minimized, and precisely controlling the intensity and irradiation time of the beam and the shape of the irradiation area of the light are required.
In the step S05, the main process is to adjust the relevant data of the treatment device through real-time detection and feedback, determine the effect of laser treatment by using a real-time detection technology, and feed back to the treatment device to adjust the laser parameters in real time, such as Optical Coherence Tomography (OCT) or a multiphoton microscope, so as to monitor the effect of laser treatment. Thus, the laser parameters can be adjusted based on real-time feedback to ensure that the virus is effectively destroyed while minimizing damage to normal cells.
Other modes of feedback also include dividing the treatment device into a plurality of batches of irradiation, observing the state of the focus and the state of normal cells near the focus area through an imaging technology after one or two times of irradiation, determining the change of the focus, and changing the relevant parameters of the treatment device in the next irradiation treatment according to the change of the focus.
Meanwhile, the ultraviolet rays with the wavelength smaller than 280nm are relatively opaque, so that the penetration intensity of external light can be weakened due to the influence of external environment, a plurality of transparent carriers are needed to be added on the surface of the body to maintain the penetration intensity of the ultraviolet rays, and the penetration depth of the ultraviolet rays can be promoted by using transparent carriers or materials, such as transparent gel, transparent hydrogel, transparent liquid and the like. These carriers can reduce scattering and absorption during the propagation of light.
Basic principle of resonance sterilization of ultraviolet laser light with wavelength of 260nm used in the text:
the viral nucleic acid and the nucleic acid of the common protein have different absorption spectra. Although they are composed of nucleic acid molecules, they differ in structure and composition, resulting in their absorption properties for light. Viral nucleic acids consist mainly of DNA or RNA, whereas nucleic acids of common proteins refer to nucleic acid molecules present in certain proteins, such as transcription factors. Wherein, the absorption spectrum of DNA and RNA has specific absorption peaks in the ultraviolet-visible spectrum range. The absorbance peak of DNA is usually located around 260nm, while the absorbance peak of RNA is located between 260-280 nm. This is because the bases (adenine, guanine, cytosine and thymine) in DNA and RNA have absorption properties in the ultraviolet spectral range, particularly at wavelengths around 260 nm. In contrast, nucleic acids of common proteins do not typically contain a large number of bases, and therefore their absorption spectra do not show a significant absorption peak in the ultraviolet-visible spectral range. The absorption spectrum of proteins is mainly represented in the longer wavelength visible region. Thus, by measuring the absorbance of a sample at a specific wavelength, it is possible to distinguish between viral nucleic acids and nucleic acids of common proteins based on the difference in the position and intensity of the absorption peak. This method is often used in laboratory applications such as virus detection and nucleic acid purification.
The virus cells have a characteristic spectrum different from that of normal human cells. This is because viral cells differ from normal cells in structure, composition and function, and these differences are manifested in the spectrum. The specific reason is that: a virus is a microorganism that invades a host cell and replicates itself therein. Viruses have different compositions and structures of proteins, nucleic acids, or other biological macromolecules than normal cells. These differences result in the ability of viruses and normal human cells to observe different absorption, scattering or emission characteristics in the spectrum. Currently, there are a number of techniques available for studying the spectral characteristics of viral cells, such as infrared, raman, fluorescence, etc. These techniques can provide information about the chemical composition of the virus cells, protein structure, nucleic acid content, etc. By comparing the spectral characteristics of viral cells with those of normal cells, we can help to understand the mechanism of viral infection, diagnose disease, and develop new therapeutic strategies.
It should be noted that the spectral characteristics of a virus may be affected by a variety of factors, such as the type of virus, strain variation, and host cell. Therefore, in practical application, the clinical society records and determines the characteristic spectrum corresponding to each virus cell, and in the detection of the characteristic spectrum, the virus can be directly determined according to the analysis result of the spectrum equipment.
In addition, in the practical use of the characteristic spectrum, a doctor can roughly judge the etiology and pathology according to the specific condition of a patient and the experience rule, so that in the process of obtaining the virus type through the detection of the characteristic spectrum, the corresponding virus is not diffusely and purposely searched, but is determined in a certain range interval, and the accuracy and the efficiency of the detection result are greatly improved.
Determination of absorbance spectra of substances (including viral cells): resonance absorption occurs when the radio frequency is close to the nuclear resonance frequency of the sample material. Resonance absorption results in a decrease in the intensity of the transmitted wave (wave passing through the sample) at the resonance frequency point, forming an absorption peak. In nmr experiments, a common measurement method is to obtain an absorption peak by detecting the attenuation of a transmitted wave (transfer function). After the radio frequency radiation passes through the sample, the intensity of the transmitted wave is reduced by resonance absorption. By measuring the relation between the intensity of the transmitted wave and the radio frequency, an absorption spectrum, i.e., the shape of the absorption peak, can be obtained.
The intensity and shape of the absorption peaks provide information about the structure and properties of the sample. By analyzing the absorption peaks, information such as chemical environment, relative quantity and the like of different atomic nuclei in the sample can be deduced. Thus, the absorption peak is measured from the decay of the transmitted wave, for understanding the nuclear magnetic resonance behavior of the sample.
The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand the present invention and implement it without limiting the scope of the present invention. All equivalent changes or modifications made in accordance with the spirit of the present invention should be construed to be included in the scope of the present invention.
Claims (9)
1. An ultraviolet radiation therapy apparatus characterized in that: the medical device comprises a main body (10), wherein a driving part (13) is fixedly arranged on the main body (10), a treatment part (12) is further arranged on the main body (10), the treatment part is arranged on the driving part (13), and a control panel (11) for controlling the treatment part (12) is further arranged on the main body (10);
The treatment member (12) includes an ultraviolet laser emitter (15) for emitting ultraviolet laser light;
an ultraviolet laser wavelength controller (14) for controlling the power of the ultraviolet laser;
an ultraviolet emission aperture adjusting device (16) for adjusting the diameter of the optical emission wave;
an optical collimator (17) for emitting ultraviolet laser light parallel to each other;
An ultraviolet light emission gun (18); for directing an ultraviolet laser to the focal location.
2. An ultraviolet radiation therapy device as defined in claim 1, wherein: the ultraviolet laser wavelength controller (14) emits ultraviolet laser with a wavelength of 260+ -5 nm.
3. An ultraviolet radiation therapy device as defined in claim 1, wherein: the ultraviolet laser transmitter (15) controls the emitted ultraviolet laser at 25 watts.
4. A method of using an ultraviolet radiation therapy device, characterized by:
s01, determining virus characteristic frequency;
S02, laser tuning;
S03, focus positioning;
S04, adjusting parameters of the treatment equipment;
S05, carrying out irradiation treatment, and monitoring and feeding back in real time.
5. A method of using an ultraviolet radiation therapy device as defined in claim 4, wherein: in the above step S01, the characteristic frequency of the target virus is accurately determined using a spectroscopic analysis technique.
6. A method of using an ultraviolet radiation therapy device as defined in claim 4, wherein: in the step S02, the characteristic frequency of the virus is determined according to the step S01, and the appropriate laser wavelength is selected for tuning.
7. A method of using an ultraviolet radiation therapy device as defined in claim 4, wherein: in the above step S03, the focus position is precisely determined by the imaging technique.
8. A method of using an ultraviolet radiation therapy device as defined in claim 4, wherein: in the step S05, the effect of the laser processing is determined by using a real-time detection technology, and the effect is fed back to the treatment device to adjust the laser parameters in real time.
9. A method of using an ultraviolet radiation therapy device as defined in claim 4, wherein: the body at the focal site is covered with a layer of transparent carrier material to increase the penetration of the ultraviolet laser.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202311339770.4A CN117959607A (en) | 2023-10-17 | 2023-10-17 | Ultraviolet irradiation treatment equipment and use method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202311339770.4A CN117959607A (en) | 2023-10-17 | 2023-10-17 | Ultraviolet irradiation treatment equipment and use method |
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| CN117959607A true CN117959607A (en) | 2024-05-03 |
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| CN202311339770.4A Pending CN117959607A (en) | 2023-10-17 | 2023-10-17 | Ultraviolet irradiation treatment equipment and use method |
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- 2023-10-17 CN CN202311339770.4A patent/CN117959607A/en active Pending
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