CN117940150A - 用于调控异常基因表达的系统和方法 - Google Patents

用于调控异常基因表达的系统和方法 Download PDF

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Publication number
CN117940150A
CN117940150A CN202280056393.0A CN202280056393A CN117940150A CN 117940150 A CN117940150 A CN 117940150A CN 202280056393 A CN202280056393 A CN 202280056393A CN 117940150 A CN117940150 A CN 117940150A
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target gene
gene
heterologous
cells
krab
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Chinese (zh)
Inventor
亚历山德拉·西尔维·科林德拉赫泰特
曹雯婷
阿比纳夫·阿迪卡里
锡达拉朱·博雷高达
丹尼尔·O·哈特
托马斯·布莱尔·盖努斯
乔瓦尼·卡罗索
杨潇
蒂莫西·戴利
涛·阮·武·隆
刘艳霞
可登宇
安布尔·鲁斯·萨尔兹曼
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Epicrispil Biotechnology Co
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Epicrispil Biotechnology Co
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Publication of CN117940150A publication Critical patent/CN117940150A/zh
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CN202280056393.0A 2021-06-17 2022-06-16 用于调控异常基因表达的系统和方法 Pending CN117940150A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163211791P 2021-06-17 2021-06-17
US63/211,791 2021-06-17
PCT/US2022/033797 WO2022266324A1 (en) 2021-06-17 2022-06-16 Systems and methods for regulating aberrant gene expressions

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CN117940150A true CN117940150A (zh) 2024-04-26

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US (1) US20240216482A1 (https=)
EP (1) EP4355357A4 (https=)
JP (1) JP2024523394A (https=)
KR (1) KR20240032038A (https=)
CN (1) CN117940150A (https=)
AU (1) AU2022293494A1 (https=)
CA (1) CA3221874A1 (https=)
GB (1) GB2624791A (https=)
IL (1) IL309174A (https=)
MX (1) MX2023014750A (https=)
WO (1) WO2022266324A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119955797A (zh) * 2025-01-13 2025-05-09 江南大学 Kif5b基因在调控成肌细胞生理活性中的功能和应用
CN119954926A (zh) * 2025-03-11 2025-05-09 华南农业大学 Klf5转录因子在调控猪骨骼肌发育中的应用及方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3192654A1 (en) 2020-09-01 2022-03-10 The Board Of Trustees Of The Leland Stanford Junior Unversity Synthetic miniature crispr-cas (casmini) system for eukaryotic genome engineering
CN119137268A (zh) 2022-03-01 2024-12-13 埃皮克里斯皮尔生物技术公司 工程化核酸酶、组合物及其使用方法
CN121127598A (zh) * 2023-03-16 2025-12-12 埃皮克里斯皮尔生物技术公司 用于调控异常基因表达的系统和方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190127713A1 (en) * 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
EP3515506B1 (en) * 2016-09-23 2023-09-13 University of Massachusetts Silencing of dux4 by recombinant gene editing complexes
EP3906308A1 (en) * 2018-12-31 2021-11-10 Research Institute at Nationwide Children's Hospital Dux4 rna silencing using rna targeting crispr-cas13b
WO2022133062A1 (en) * 2020-12-16 2022-06-23 Epicrispr Biotechnologies, Inc. Systems and methods for engineering characteristics of a cell

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119955797A (zh) * 2025-01-13 2025-05-09 江南大学 Kif5b基因在调控成肌细胞生理活性中的功能和应用
CN119954926A (zh) * 2025-03-11 2025-05-09 华南农业大学 Klf5转录因子在调控猪骨骼肌发育中的应用及方法

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Publication number Publication date
JP2024523394A (ja) 2024-06-28
GB202319324D0 (en) 2024-01-31
KR20240032038A (ko) 2024-03-08
CA3221874A1 (en) 2022-12-22
AU2022293494A1 (en) 2024-01-04
WO2022266324A1 (en) 2022-12-22
US20240216482A1 (en) 2024-07-04
EP4355357A1 (en) 2024-04-24
EP4355357A4 (en) 2025-08-20
GB2624791A (en) 2024-05-29
MX2023014750A (es) 2024-03-08
IL309174A (en) 2024-02-01

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