CN117919599A

CN117919599A - Electrode slice, electrode slice abnormality detection method and tumor electric field treatment system

Info

Publication number: CN117919599A
Application number: CN202410011962.0A
Authority: CN
Inventors: 陈凯健; 张军; 孙虎; 惠嘉杰
Original assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Current assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Priority date: 2022-12-30
Filing date: 2022-12-30
Publication date: 2024-04-26
Also published as: CN116046198A; CN117919598A; CN117883697A; CN116046198B

Abstract

The invention discloses an electrode slice, an electrode slice abnormality detection method and a tumor electric field treatment system, wherein the electrode slice comprises: a plurality of electrode elements and a plurality of temperature sensors arranged in a plurality of row groups, a plurality of column groups on a circuit connection; the corresponding temperature sensors in each row group are connected in series, and the grounding ends of the corresponding temperature sensors in each column group are connected together, wherein whether the abnormal temperature sensors exist in the electrode plate is judged based on temperature signals detected by corresponding one or more combinations of all the sampled temperature sensors of the electrode plate. Thus, 100% coverage of the temperature sensor is achieved without increasing the number of cable cores, and an abnormal temperature sensor can be detected.

Description

Electrode slice, electrode slice abnormality detection method and tumor electric field treatment system

The application is a divisional application of an application patent application with the application date of 2022, 12 months and 30 days, the application number of 202211721902.5, and the application creative name of electrode slice, electrode slice temperature detection method and tumor electric field treatment system.

Technical Field

The invention relates to the technical field of medical equipment, in particular to an electrode slice, an electrode slice abnormality detection method and a tumor electric field treatment system.

Background

Tumor electric field therapy is a tumor therapy method which utilizes an electric field generator to generate a low-intensity, medium-high-frequency alternating electric field to interfere with the mitosis process of tumor cells. The electric field applied by the treatment method can influence the aggregation of tubulin, prevent the formation of spindle body, inhibit the mitosis process and induce the apoptosis of cancer cells.

Currently, tumor electric field therapy systems mainly include an electric field generator, an adapter electrically connected to the electric field generator, and a plurality of pairs of electrode plates electrically connected to the electric field generator through the adapter. The electric field generator transmits alternating electric signals for tumor electric field treatment to each electrode slice through the adapter, and then alternating electric fields are applied to tumor parts of patients through the paired electrode slices to carry out tumor electric field treatment. When the electric field is applied to the body of a patient, heat is accumulated at the corresponding position of the electrode plate, which is applied to the skin, so that the temperature of the electrode plate, which corresponds to the tumor part of the patient, needs to be monitored in real time, and when the temperature of the body surface is too high, the intensity of the alternating electric field needs to be adjusted in time, so that low-temperature scalding of the skin of the patient caused by the too high temperature is avoided.

In the related art, the electrode plates are provided with a thermistor element on the corresponding electrode element, and the plurality of thermistor elements are connected in parallel, and the temperature change of the corresponding electrode element is monitored in real time through the resistance change of the thermistor element. For example, in an electrode sheet having 9 electrode elements, in which 8 thermistor elements are provided and resistance values of the 8 thermistor elements are transmitted through a 10-core cable including 1 alternating current signal line (AC line), 1 ground line, 8 signal lines, the coverage of the thermistor elements in the electrode sheet is about 89% (8/9≡0.89). When the number of the thermistor elements is increased, if the number of the thermistor elements is kept unchanged, the phenomenon of low-temperature scald of the skin of the patient is easy to occur, for example, 8 thermistor elements are arranged in an electrode sheet with 20 electrode elements, the coverage rate of the thermistor elements in the electrode sheet is about 40% (8/20=0.4), that is, the temperature of more than half of the electrode elements cannot be monitored, and the phenomenon of low-temperature scald of the skin of the patient is easy to occur. If a thermistor element is arranged on each electrode element to keep the coverage rate of the thermistor element, more cables with multiple cores are needed, but the cables become thicker, the softness of the cables becomes hard, the difficulty in fixing the cables is increased, meanwhile, the whole weight of the electrode plate is increased due to the increase of the cable cores, the adhesion effect between the electrode plate and the corresponding body surface of the tumor part of the patient is affected, the load of the patient is increased, and discomfort is caused.

Disclosure of Invention

The present invention aims to solve at least one of the technical problems in the related art to some extent. Therefore, a first object of the present invention is to provide an electrode sheet for an electric tumor field therapy system, which can achieve a larger coverage rate of a temperature sensor without increasing the number of cable cores, avoid overstressing the electrode sheet, maintain the application effect of the electrode sheet, and detect an abnormal temperature sensor.

A second object of the present invention is to propose a tumour electric field therapy system.

A third object of the present invention is to propose a tumour treatment device.

The fourth object of the present invention is to provide an electrode slice abnormality detection method for a tumor electric field therapy system.

A fifth object of the present invention is to propose a computer readable storage medium.

A sixth object of the present invention is to propose an adapter for an electric field tumour treatment system.

A seventh object of the present invention is to propose an electric field generator for a tumour electric field therapy system.

To achieve the above object, the present invention provides an electrode pad for an electric field tumor treatment system, comprising: a plurality of electrode elements, each of which is operable to apply an alternating electric field; a plurality of temperature sensors, each of the temperature sensors being arranged in correspondence with one of the electrode elements to detect a temperature at the corresponding electrode element, each of the temperature sensors having a signal terminal and a ground terminal, the plurality of temperature sensors being configured in a circuit connection as a plurality of row groups, a plurality of column groups, the corresponding temperature sensors in each of the row groups being connected in series, the ground terminals of the corresponding temperature sensors in each of the column groups being connected together; whether the abnormal temperature sensor exists in the electrode slice is judged based on temperature signals detected by corresponding one or more combinations in all the sampled temperature sensors of the electrode slice.

According to the electrode slice provided by the embodiment of the invention, the plurality of temperature sensors are configured into the plurality of row groups and the plurality of column groups, the corresponding temperature sensors in each row group are connected in series, the grounding ends of the corresponding temperature sensors in each column group are connected together, whether the abnormal temperature sensors exist in the electrode slice can be judged based on the temperature signals detected by the corresponding one or more combinations in all the sampled temperature sensors of the electrode slice, so that the coverage rate of the temperature sensors can be 100% under the condition that the number of cable cores is not increased, the excessive load of the electrode slice is avoided, the application effect of the electrode slice is kept, and the abnormal temperature sensors can be detected.

Further, the corresponding temperature sensors in each row group are connected in series and then connected with a first switch, and the grounding ends of the corresponding temperature sensors in each column group are connected together and then connected with a second switch; whether the abnormal temperature sensor exists in the electrode slice is judged through the configuration of the switch combination relation of the first switch and the second switch and the temperature signals detected by corresponding one or more combinations in all the temperature sensors of the electrode slice sampled based on the switch combination relation of the first switch and the second switch.

Further, after the corresponding temperature sensors in each row group are connected in series, the first switch and the voltage dividing resistor are connected in series, and after the grounding ends of the corresponding temperature sensors in each column group are connected together, the grounding ends of the corresponding temperature sensors are connected to a grounding pin through the second switch.

Further, the electrode pad further comprises a plurality of diodes, each diode has an anode and a cathode, each diode is corresponding to one temperature sensor, wherein the grounding end of the corresponding temperature sensor in each column group is connected with the anode of the corresponding diode, and then connected to the corresponding second switch through the cathode of the corresponding diode.

Further, the temperature sensor is a thermistor.

Further, the circuit further comprises a substrate, and the divider resistor, the first switch and the second switch are all arranged outside the substrate.

Further, the electrode element is a dielectric element.

Further, the dielectric element is a ceramic plate.

Further, each of the electrode members is provided with a through hole adapted to mount the temperature sensor.

Further, a plurality of the electrode elements are connected in parallel to an alternating current signal line.

Further, the plurality of electrode elements are configured in a plurality of row groups and a plurality of column groups on the circuit connection, and the number of the electrode elements of each row group is the same as the number of the temperature sensors, and the number of the electrode elements of each column group is the same as the number of the temperature sensors.

Further, the number of the electrode elements is 20, and the electrode elements are arranged in four rows and five columns on the circuit connection; or the number of the electrode elements is 9, and the electrode elements are arranged in three rows and three columns on the circuit connection.

Further, a plurality of the electrode elements are arranged in a substantially array in a spatial arrangement.

Further, the number of the first switches is equal to the number of the row groups, and the number of the second switches is equal to the number of the column groups.

Further, the sum of the numbers of the first switch and the second switch is not more than 9.

In order to achieve the above purpose, the invention also provides a tumor electric field treatment system. A tumor electric field therapy system, comprising: at least one pair of the electrode sheets; and the controller is used for judging whether the abnormal temperature sensor exists in the corresponding electrode slice or not based on the temperature signals detected by the corresponding one or more combinations of all the sampled temperature sensors of the electrode slice.

According to the tumor electric field treatment system, through the electrode plates, the coverage rate of the temperature sensor can be increased under the condition that the number of cable cores is not increased, the overload of the electrode plates is avoided, the application effect of the electrode plates is maintained, and the temperature sensor with faults can be detected.

Further, in the case that the electrode pad includes a first switch and a second switch, the controller is further configured to determine whether an abnormal temperature sensor exists in the corresponding electrode pad by configuring a switch combination relationship of the first switch and the second switch, and based on a temperature signal detected by a corresponding one or more combinations of all the temperature sensors of the electrode pad sampled by the switch combination relationship of the first switch and the second switch.

Further, the number of the electrode plates is four.

In order to achieve the above purpose, the invention also provides a tumor treatment device. A tumor treatment apparatus comprising: at least one pair of electrode plates, or the tumor electric field treatment system.

According to the tumor treatment equipment provided by the invention, through the electrode plate or the tumor electric field treatment system, the coverage rate of the temperature sensor can be increased under the condition that the number of cable cores is not increased, the overload of the electrode plate is avoided, the application effect of the electrode plate is maintained, and the temperature sensor with faults can be detected.

In order to achieve the above purpose, the invention also provides an electrode slice abnormality detection method for the tumor electric field treatment system. An electrode slice abnormality detection method for a tumor electric field treatment system, wherein the electrode slice is the electrode slice, and the method comprises the following steps: s210: sampling temperature signals detected by corresponding one or more combinations in all temperature sensors of the electrode plate; s220: judging whether an abnormal temperature sensor exists in the electrode plate according to the temperature signals detected by each sampled temperature sensor.

According to the electrode slice abnormality detection method for the tumor electric field treatment system, provided by the invention, the temperature signals detected by each temperature sensor are sampled, and whether the electrode slice has an abnormal temperature sensor or not is judged according to the temperature signals obtained by sampling, so that the abnormal temperature sensor can be detected.

Further, in the case that the electrode sheet includes a first switch and a second switch, the step S210 further includes: the switching time sequences of the first switch and the second switch are configured to sample temperature signals detected by corresponding one or more combinations of all temperature sensors of the electrode plate.

Further, under the condition that the number of the temperature sensors of each row group and the number of the temperature sensors of each column group of the electrode sheet are determined, after the step S210, the method further includes:

Determining a switch combination relationship of the first switch and the second switch;

And judging whether an abnormal temperature sensor exists in the corresponding electrode slice according to the switch combination relation of the first switch and the second switch and the sampled temperature signals detected by each temperature sensor.

To achieve the above object, the present invention also provides a computer-readable storage medium. A computer-readable storage medium having stored thereon an electrode abnormality detection program for a tumor electric field therapy system, which when executed by a controller, implements the aforementioned electrode abnormality detection method for a tumor electric field therapy system.

The invention provides a computer readable storage medium, which can detect abnormal temperature sensor by executing the electrode slice abnormality detection method.

In order to achieve the above purpose, the invention also provides an adapter for the tumor electric field treatment system. An adapter for a tumor electric field treatment system comprises a memory, a controller and an electrode plate abnormality detection program which is stored in the memory and can run on the controller and is used for the tumor electric field treatment system, wherein the electrode plate abnormality detection method for the tumor electric field treatment system is realized when the controller executes the electrode plate abnormality detection program for the tumor electric field treatment system.

The adapter for the tumor electric field treatment system provided by the invention can detect abnormal temperature sensors by executing the electrode slice abnormality detection method.

In order to achieve the above purpose, the invention also provides an electric field generator for the tumor electric field treatment system. The electric field generator for the tumor electric field treatment system comprises a memory, a controller and an electrode slice abnormality detection program which is stored in the memory and can run on the controller and is used for the tumor electric field treatment system, wherein the electrode slice abnormality detection method for the tumor electric field treatment system is realized when the controller executes the electrode slice abnormality detection program for the tumor electric field treatment system.

The invention provides an electric field generator for a tumor electric field treatment system, which can detect abnormal temperature sensors by executing the electrode slice abnormality detection method.

Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.

Drawings

FIG. 1 is a schematic diagram of a tumor electric field therapy system according to an embodiment of the invention;

FIG. 2 is a schematic block diagram of one of the electrode pads and an adapter of FIG. 1;

FIG. 3 is a schematic block diagram of the internal structure of the adapter of FIG. 1;

fig. 4 is a flow chart of a method for detecting the temperature of an electrode pad of a tumor electric field therapy system according to a first embodiment of the invention.

Reference numerals:

1000. A tumor electric field treatment system; 100. x1, Y1, X2 and Y2 electrode sheets; 111. a substrate; 112. an electrode element; 113. a temperature sensor; 113A, signal terminals; 113B, ground; 114. a diode; 114A, anode; 114B cathode; 115. a first cable; 120. an adapter; 121. a temperature detection switch unit; 122. an ADC sampling unit; 123. a controller; 124. a serial port communication unit; 125. a second cable; 126. an inverter; 130. an electric field generator; 140. a first connector; 141. a first plug; 142. a first socket; 150. a second connector; 151. a second plug; 152. a second socket; k1, K2, K3 and K4, a first switch; k5, K6, K7, K8 and K9, a second switch; R1-R16, divider resistance; VCC, direct current power supply; GND, ground pin.

Detailed Description

Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative and intended to explain the present invention and should not be construed as limiting the invention.

Referring to fig. 1, a tumor electric field therapy system 1000 includes: at least one pair of electrode pads 100, an adapter 120 electrically connected to each electrode pad 100, and an electric field generator 130 electrically connected to the adapter 120. At least one pair of electrode pads 100 are arranged in pairs on the body surface of the patient, such as four electrode pads X1, Y1, X2, and Y2 in fig. 1, and each two electrode pads are applied as a pair to the body surface corresponding to the tumor site of the patient. The electric field generator 130 is configured to generate an alternating electric signal, and to switch and transmit the alternating electric signal to at least one pair of electrode pads 100 through the adapter 120, where each pair of electrode pads 100 applies the alternating electric signal to a tumor site of a patient, so that a therapeutic alternating electric field (i.e., a tumor therapeutic electric field) is generated between the same pair of electrode pads 100, and acts on the tumor site of the patient to perform tumor therapy on the patient. The alternating electrical signals applied by two electrode plates 100 in the same pair of electrode plates 100 are different, and the two electrode plates 100 respectively apply a group of alternating electrical signals with opposite polarities and generate an alternating electric field in one direction between the two electrode plates 100. Alternating electric fields of different directions are generated between different pairs of electrode plates 100.

As shown in fig. 2, each electrode tab 100 includes a substrate 111, a plurality of electrode elements 112 disposed on the substrate 111, and a plurality of temperature sensors 113. As shown in fig. 1, a plurality of electrode elements 112 are arranged in a generally array, each electrode element 112 being capable of applying an alternating electrical signal. The same alternating electrical signal is applied to a plurality of electrode elements 112 of the same electrode sheet 100. Each temperature sensor 113 is provided corresponding to one electrode element 112, and the number of the temperature sensors 113 is equal to the number of the electrode elements 112, that is, the coverage rate of the temperature sensors 113 on the electrode sheet 100 reaches 100%. As shown in fig. 2, in the present embodiment, each electrode sheet 100 includes 20 electrode elements 112, and each electrode element 112 is provided with a temperature sensor 113, and the temperature at the corresponding electrode element 112 is detected by the temperature sensor 113.

Each electrode element 112 is provided with a through hole 116, and a corresponding temperature sensor 113 is accommodated in the through hole 116, so that the temperature of each electrode element 112 is monitored in real time, and the phenomenon that the temperature of the body surface of a patient is too high to cause low-temperature burn of the patient due to the fact that the temperature of part of electrode elements 112 cannot be monitored is avoided. As shown in fig. 2, the perforation 116 of each electrode member 112 is located in the middle thereof. In this embodiment, the electrode element 112 is a dielectric element, and preferably, the electrode element 112 is a ceramic plate.

As shown in fig. 2, the plurality of electrode elements 112 and the plurality of temperature sensors 113 disposed correspondingly are each configured in terms of circuit connection structure into at least three row groups and at least three column groups. It should be noted that the arrangement is for better illustrating the internal portion of the electrode sheet 100 and the electrical connection between the electrode sheet 100 and the adaptor 120, and does not represent the arrangement of the electrode elements 112 in a space structure, which may be a substantially array structure as shown in fig. 1. The number of the electrode elements 112 and the number of the temperature sensors 113 in the same row group are the same, and the number of the electrode elements 112 and the number of the temperature sensors 113 in the same column group are the same. The plurality of electrode elements 112 of each row group are all connected in parallel to the same line, and the parallel lines of the plurality of electrode elements 112 of each row group are connected in series to form a line, which is an alternating current signal line (AC line) for transmitting an alternating current electric signal to the plurality of electrode elements 112.

Two ends of each temperature sensor 113 are a signal end 113A and a ground end 113B, respectively. The plurality of temperature sensors 113 located in the same row group are connected in series, and after one signal terminal 113A located at the end of each row group is connected to the direct current power supply VCC through a first switch (one of K1, K2, K3, and K4) and a voltage dividing resistor (one of R1, R2, R3, and R4) connected in series, the ground terminal 113B of the corresponding temperature sensor 113 in each column group is connected together, and is connected to the ground pin GND through a second switch (one of K5, K6, K7, K8, and K9), the sum of the numbers of the first switches (K1-K4) and the second switches (K5-K9) is not more than 9, so that analog temperature signals detected by configuring the switching timing of the first switches and the second switches so that the corresponding one or more combinations of all the temperature sensors 113 of the electrode pad 100 are sampled, respectively.

In this embodiment, each electrode sheet has 20 electrode elements 112, and the 20 electrode elements 112 are configured in four row groups and five column groups. Each row group has five temperature sensors 113 and each column group has four temperature sensors 113. The 20 electrode elements 112 are topologically connected and connected in parallel to one alternating current signal line (AC line) to be transferred with an alternating current signal line (AC line) and form a therapeutic electric field for treating tumor between the opposite electrode pads 100. After the corresponding five temperature sensors 113 in each row group are connected in series, they are connected to the direct current power supply VCC through a first switch (one of K1, K2, K3, and K4) and a voltage dividing resistor (one of R1, R2, R3, and R4) connected in series, and after the ground terminals 113B of the corresponding four temperature sensors 113 in each column group are connected together, they are connected to the ground pin GND through a second switch (one of K5, K6, K7, K8, and K9) so as to sample analog temperature signals detected by the corresponding temperature sensors 113, respectively, by configuring the switching timings of the first switches (K1, K2, K3, and K4) and the second switches (K5, K6, K7, K8, and K9). As shown in fig. 2, all the temperature sensors 113 in the same row group are connected in series to form a circuit (such as one of the circuits 1,2, 7, 8 or 9) and are connected to the dc power VCC through a circuit connected to the signal terminal 113A at the end of each row group, the ground terminals 113B of all the temperature sensors 113 in the same row group are respectively connected to the ground pin GND by 5 ground lines (such as the ground lines 5, 6, 7, 8 and 9) in one-to-one correspondence, the ground terminals 113B of all the temperature sensors 113 in the same column group are connected to the same ground line (such as one of the ground lines 5, 6, 7, 8 or 9), and the temperature sensors 113 in each row group are connected in series to a first switch (such as one of the first switches K1, K2, K3 and K4) and a voltage dividing resistor (such as one of the voltage dividing resistors R1, R2, R3 and R4) at the end of the dc power VCC, and a voltage dividing resistor (such as one of the voltage dividing resistors R1, R2, R3 and R4) and a first switch (such as the first switch 5, K3 and a second switch (such as the first switch 7, K2, K3 and a second switch) are connected in series to the ground line (such as the first switch 7, K2 and the first switch 7 and the second switch) and the first switch (such as the first switch 7, K4) and the second switch) and the first switch (7 and the second switch) and the ground). It should be noted that the types of the first switch and the second switch are not limited, and may be a normally open switch or a normally closed switch, or may be an active switch tube or a passive switch tube.

Specifically, referring to fig. 2, five temperature sensors 113 (corresponding to serial numbers 1, 2, 3, 4, and 5) in the first row group are connected in series end to form a line 1 connected to the dc power supply VCC and connected to the first switch K1 and the voltage dividing resistor R1, the ground 113B of the first temperature sensor 113 (corresponding to serial number 1) in the first row group is connected to the ground 5 and connected to the second switch K5, the ground 113B of the second temperature sensor 113 (corresponding to serial number 2) is connected to the ground 6 and connected to the second switch K6, the ground 113B of the third temperature sensor 113 (corresponding to serial number 3) is connected to the ground 7 and connected to the second switch K7, the ground 113B of the fourth temperature sensor 113 (corresponding to serial number 4) is connected to the ground 8 and connected to the second switch K8, and the ground 113B of the fifth temperature sensor 113 (corresponding to serial number 5) is connected to the ground 9 and connected to the second switch K9.

Five temperature sensors 113 (corresponding to serial numbers 6, 7, 8, 9 and 10) in the second row group are connected in series end to form a circuit 2, the circuit 2 is connected to a direct current power supply VCC and connected with a first switch K2 and a voltage dividing resistor R2, a grounding end 113B of a first temperature sensor 113 (corresponding to serial number 6) in the second row group is connected with a grounding wire 5 and connected with a second switch K5, a grounding end 113B of a second temperature sensor 113 (corresponding to serial number 7) is connected with the grounding wire 6 and connected with the second switch K6, a grounding end 113B of a third temperature sensor 113 (corresponding to serial number 8) is connected with the grounding wire 7 and connected with a second switch K7, a grounding end 113B of a fourth temperature sensor 113 (corresponding to serial number 9) is connected with the grounding wire 8 and connected with the second switch K8, and a grounding end 113B of a fifth temperature sensor 113 (corresponding to serial number 10) is connected with the grounding wire 9 and connected with the second switch K9.

Five temperature sensors 113 (corresponding to serial numbers 11, 12, 13, 14 and 15) in the third row group are connected in series end to form a circuit 3, the circuit 3 is connected to a direct current power supply VCC and is connected with a first switch K3 and a voltage dividing resistor R3, a grounding end 113B of a first temperature sensor 113 (corresponding to serial number 11) in the third row group is connected with a grounding wire 5 and is connected with a second switch K5, a grounding end 113B of a second temperature sensor 113 (corresponding to serial number 12) is connected with a grounding wire 6 and is connected with a second switch K6, a grounding end 113B of a third temperature sensor 113 (corresponding to serial number 13) is connected with a grounding wire 7 and is connected with a second switch K7, a grounding end 113B of a fourth temperature sensor 113 (corresponding to serial number 14) is connected with a grounding wire 8 and is connected with a second switch K8, and a grounding end 113B of a fifth temperature sensor 113 (corresponding to serial number 15) is connected with a grounding wire 9 and is connected with a second switch K9.

Five temperature sensors 113 (corresponding to serial numbers 16, 17, 18, 19 and 20) in the fourth row group are connected in series end to form a circuit 4, which is connected to the direct current power supply VCC and is connected to the first switch K4 and the voltage dividing resistor R4, the ground terminal 113B of the first temperature sensor 113 (corresponding to serial number 16) in the fourth row group is connected to the ground line 5 and is connected to the second switch K5, the ground terminal 113B of the second temperature sensor 113 (corresponding to serial number 17) is connected to the ground line 6 and is connected to the second switch K6, the ground terminal 113B of the third temperature sensor 113 (corresponding to serial number 18) is connected to the ground line 7 and is connected to the second switch K7, the ground terminal 113B of the fourth temperature sensor 113 (corresponding to serial number 19) is connected to the ground line 8 and is connected to the second switch K8, and the ground terminal 113B of the fifth temperature sensor 113 (corresponding to serial number 20) is connected to the ground line 9 and is connected to the second switch K9.

Each electrode pad 100 further includes a plurality of diodes 114, and each diode 114 is disposed corresponding to one of the temperature sensors 113. Diode 114 has an anode 114A and a cathode 114B. The ground terminals 113B of the respective temperature sensors 113 in each column group are connected to the anode 114A of the corresponding diode 114, and then connected together through the cathode 114B of the corresponding diode 114. As shown in fig. 2, a diode 114 is correspondingly connected to the ground terminal 113B of each temperature sensor 113 (corresponding to numbers 1, 6, 11 and 16) of the first column group, and the anode 114A of the diode 114 is connected to the ground terminal 113B of the corresponding temperature sensor 113, and the cathode 114B of each diode 114 of the first column group is connected to the ground line 5; the grounding end 113B of each temperature sensor 113 (corresponding to serial numbers 2, 7, 12 and 17) of the second column group is respectively and correspondingly connected with one diode 114, the anode 114A of the diode 114 is connected with the grounding end 113B of the corresponding temperature sensor 113, and the cathode 114B of each diode 114 of the second column group is connected to the grounding wire 6; the grounding end 113B of each temperature sensor 113 (corresponding to serial numbers 3, 8, 13 and 18) of the third column group is respectively and correspondingly connected with one diode 114, the anode 114A of the diode 114 is connected with the grounding end 113B of the corresponding temperature sensor 113, and the cathode 114B of each diode 114 of the third column group is connected to the grounding wire 7; the grounding end 113B of each temperature sensor 113 (corresponding to serial numbers 4, 9, 14 and 19) of the fourth column group is respectively and correspondingly connected with one diode 114, the anode 114A of the diode 114 is connected with the grounding end 113B of the corresponding temperature sensor 113, and the cathode 114B of each diode 114 of the fourth column group is connected to the grounding wire 8; the ground terminals 113B of the temperature sensors 113 (corresponding to the numbers 5, 10, 15, and 20) of the fifth column group are respectively connected to one diode 114, and the anode 114A of the diode 114 is connected to the ground terminal 113B of the corresponding temperature sensor 113, and the cathode 114B of each diode 114 of the fifth column group is connected to the ground line 9. That is, a diode 114 is connected between the ground terminal 113B and the ground pin GND of all the temperature sensors 113 in the same column group, and the diode 114 can effectively prevent the other temperature sensors 113 from affecting the resistance values of the corresponding temperature sensors 113 detected by the switching timing control of the first switch and the second switch.

As shown in fig. 1-3, a first connector 140 is connected between each electrode tab 100 and the adapter 120, the first connector 140 being adapted to connect the respective electrode tab 100 to the adapter 120. Each electrode plate 100 has a first cable 115 electrically connected to the substrate 111 thereof, and the first connector 140 includes a first plug 141 disposed at an end of the first cable 115 remote from the substrate 111 and a first socket 142 disposed on the adapter 120. The first plug 141 and the first socket 142 are push-type spring connectors, that is, the first connector 140 connects the adaptor 120 and the electrode sheet 100 by means of connectors.

As shown in fig. 1, four electrode pads X1, Y1, X2, and Y2 are connected to the adapter 120 through one first connector 140, respectively, wherein the electrode pads X1 and X2 are configured as one pair of electrode pads 100 and the electrode pads Y1 and Y2 are configured as the other pair of electrode pads 100. As shown in fig. 3, each first connector 140 is connected to a corresponding one of the lines a1, a2, a3 and a4 in fig. 3, respectively, to transmit an alternating electric signal of a corresponding polarity in a corresponding one of the directions, so that a therapeutic electric field for treating tumors is generated between a corresponding pair of electrode pads 100 (e.g., electrode pads X1 and X2 or electrode pads Y1 and Y2). It will be appreciated that the lines a1, a2, a3 and a4 are AC lines carrying alternating electrical signals of respective polarity in respective directions and extend into a respective one of the electrode pads 100 to provide respective alternating electrical signals to a plurality of electrode elements 112 of that electrode pad 100. The lines a1, a2, a3, and a4 are connected with a second connector 150 in a direction away from the first connector 140, and the second connector 150 is connected with the electric field generator 130. The electric field generator 130 is powered by a dc power supply, and the dc power supply is subjected to inversion, filtering and the like to generate two sets of cyclically switched alternating electric signals, wherein each set of alternating electric signals is two alternating electric signals with opposite polarities. The two sets of alternating electrical signals generated by the electric field generator 130 are transmitted to the plurality of electrode elements 112 of the corresponding one of the electrode pads 100 through the second connector 150, the corresponding one of the lines a1, a2, a3, a4, and the corresponding first connector 140, respectively. In addition, the electric field generator 130 transmits the dc power to the plurality of temperature sensors 113 of the corresponding one of the electrode pads 100 through the second connector 150, the power and ground lines of the dc power VCC inside the adapter 120, and the corresponding first connector 140, so that the corresponding temperature sensors 113 operate and generate analog temperature signals.

As shown in fig. 2-3, each first connector 140 is further connected to a set 9 of temperature-switched acquisition lines a5, a6, a7, or a8, respectively, wherein each temperature-switched acquisition line includes: 4-way lines respectively connected with the first switches K1, K2, K3 and K4 and 5-way grounding lines respectively connected with the second switches K5, K6, K7, K8 and K9. As shown in fig. 1 to 3, the first cable 115 of the electrode pad X1 is connected to 10 lines of the combination of the lines a1 and a5 to which the first connector 140 is connected. By analogy, the first cable 115 of the electrode pad Y1 is connected to 10 lines of the combination of the lines a2 and a6 connected to the first connector 140, the first cable 115 of the electrode pad X2 is connected to 10 lines of the combination of the lines a3 and a7 connected to the first connector 140, and the electrode pad Y2 is connected to 10 lines of the combination of the lines a4 and a8 connected to the first connector 140. Accordingly, as shown in fig. 1-2, the first cable 115 between each electrode pad 100 and the corresponding first connector 140 is a 10-wire cable.

As shown in fig. 2 to 3, a plurality of first switches (K1, K2, K3, and K4) and a plurality of second switches (K5, K6, K7, K8, and K9) connected to each first connector 140 constitute one temperature detection switch unit 121, and the temperature detection switch unit 121 and a voltage dividing resistor (e.g., voltage dividing resistor R1 to R4, R5 to R8, R9 to R12, or R13 to R16) connected to the first switch in each temperature detection switch unit 121 are all located in the adapter 120. The adapter 120 includes the aforementioned plurality of temperature detecting switch units 121, voltage dividing resistors (e.g., voltage dividing resistors R1-R4, R5-R8, R9-R12, or R13-R16), an ADC sampling unit 122 for collecting analog temperature signals of the corresponding temperature sensors 113, and a controller 123 for controlling time sequence on-off of the plurality of first switches and the plurality of second switches in the corresponding temperature detecting switch units 121. The controller 123 is configured to configure the switching timing of the plurality of first switches and the plurality of second switches of the temperature detection switching unit 121, select one first switch (e.g., one of K1, K2, K3, and K4) and one second switch (e.g., one of K5, K6, K7, K8, and K9) to be closed, so that the temperature sensor 113 of the corresponding electrode pad 100 is energized, so that the corresponding temperature sensor 113 generates an analog temperature signal, which is transmitted to the ADC sampling unit 122 through the corresponding first connector 140, 9-way temperature switching acquisition line (e.g., the temperature switching acquisition line a5, a6, a7, or a 8), the temperature detection switching unit 121, acquire the analog temperature signal by the ADC sampling unit 122, and then the analog temperature signal acquired by the ADC sampling unit 122 is computationally converted into a digital temperature signal by the controller 123.

The plurality of temperature detection switch units 121 in the adaptor 120 respectively pass the analog temperature signals to the corresponding channels of the ADC sampling unit 122 through one set of line groups (one set of a9, a10, a11, and a 12). As shown in conjunction with fig. 2 and 3, in the present embodiment, four temperature detection switch units 121 respectively pass analog temperature signals to the corresponding channels of the ADC sampling unit 122 through one group of line groups (one group of a9, a10, a11, and a 12). Specifically, the temperature detection switch unit 121 corresponding to the electrode pad X1 transmits the analog temperature signal generated by the temperature sensor 113 corresponding to the electrode pad X1 to the channels 1-4 of the ADC sampling unit 122 through the 4-way line group a 9; the temperature detection switch unit 121 corresponding to the electrode tab Y1 transmits the analog temperature signal generated by the temperature sensor 113 corresponding to the electrode tab Y1 to the channels 5-8 of the ADC sampling unit 122 through the 4-way line group a 10; the temperature detection switch unit 121 corresponding to the electrode pad X2 transmits the analog temperature signal generated by the temperature sensor 113 corresponding to the electrode pad X2 to the channels 9-12 of the ADC sampling unit 122 through the 4-way line group a 11; the temperature detection switch unit 121 corresponding to the electrode tab Y2 transmits the analog temperature signal generated by the temperature sensor 113 corresponding to the electrode tab Y2 to the channels 13-16 of the ADC sampling unit 122 through the 4-way line group a 12. The controller 123 controls the on-off of the plurality of first switches and the plurality of second switches in the corresponding temperature detection switching unit 121, and causes one first switch (e.g., one of K1, K2, K3, and K4) and one second switch (e.g., one of K5, K6, K7, K8, and K9) to be closed, so that the corresponding temperature sensor 113 generates an analog temperature signal, and the ADC sampling unit 122 collects the analog temperature signal and transmits the analog temperature signal to the corresponding channel of the ADC sampling unit 122 by one line connecting the closed first switches. That is, the ADC acquisition unit 122, when acquiring the analog temperature signal of the corresponding temperature sensor 113 on each electrode pad 100, transfers one line connected to the closed first switch from the corresponding line group (one of the groups a9, a10, a11, and a 12) to its corresponding channel.

As shown in fig. 2-3, the adaptor 120 further includes a serial communication unit 124, and the serial communication unit 124 transmits the digital temperature signal converted by the controller 123 to the electric field generator 130. Specifically, the controller 123 controls the on-off of the plurality of first switches and the plurality of second switches in each of the temperature detection switch units 121, and causes one of the first switches (e.g., one of K1, K2, K3, and K4) and one of the second switches (e.g., one of K5, K6, K7, K8, and K9) to be closed to sequentially obtain the analog temperature signals generated by the corresponding temperature sensors 113 in the electrode sheet 100. As shown in fig. 2, when the controller 123 controls the first switch K1 and the second switch K5 to be turned on and the other switches to be turned off, the ADC sampling unit 122 samples to obtain an analog temperature signal of the first temperature sensor 113 (corresponding to the serial number 1) of the first row group; when the controller 123 controls the first switch K1 and the second switch K6 to be turned on and the other switches to be turned off, the ADC sampling unit 122 samples to obtain the combined analog temperature signals of the first to second temperature sensors 113 (corresponding to the serial numbers 1 and 2) of the first row group; when the controller 123 controls the first switch K1 and the second switch K7 to be turned on and the other switches to be turned off, the ADC sampling unit 122 samples to obtain the combined analog temperature signals of the first to third temperature sensors 113 (corresponding to serial numbers 1, 2, and 3) of the first row group; when the controller 123 controls the first switch K1 and the second switch K8 to be turned on and the other switches to be turned off, the ADC sampling unit 122 samples to obtain analog temperature signals of the first to fourth temperature sensors 113 (corresponding to serial numbers 1, 2, 3, and 4) of the first row group; when the controller 123 controls the first switch K1 and the second switch K9 to be turned on and the other switches to be turned off, the ADC sampling unit 122 samples analog temperature signals of the first to fifth temperature sensors 113 (corresponding to serial numbers 1, 2, 3,4, and 5) of the first row group. And so on, analog temperature signals generated by the temperature sensors 113 of other row groups can be obtained. The serial communication unit 124 is controlled by the controller 123, and the digital temperature signals converted by the controller 123 are serially transmitted by the serial communication unit 124, for example, to the electric field generator 130.

Preferably, the temperature sensor 113 is a thermistor. As shown in fig. 2, when the reference numbers 1 to 20 are used as the reference numbers of the temperature measuring points, the resistance value of the thermistor corresponding to each reference number of the temperature measuring points can be represented by Rtn. For example, the resistance of the thermistor corresponding to the temperature measurement point 1 is Rt1, specifically, the resistance of the thermistor corresponding to the first thermistor of the first row group is Rt2, specifically, the resistance of the thermistor corresponding to the second thermistor of the first row group is Rt2, and so on.

After obtaining the analog temperature signal corresponding to the temperature measurement point label, the controller 123 calculates the actual temperature of the thermistor corresponding to the temperature measurement point label by the following formula (1), where the analog temperature signal is the resistance value of the corresponding one or more combinations in all the temperature sensors 113 of the electrode pad 100:

Where Tn is the actual temperature of the thermistor corresponding to the temperature measurement point reference number n, x is the analog temperature signal corresponding to the temperature measurement point reference number n obtained by sampling, span is the maximum range of the ADC sampling unit 122, for example, when the ADC sampling unit 122 adopts a 16-bit sampling chip, span is 65535, and R is the resistance of the voltage dividing resistor, such as the resistance of the voltage dividing resistor R1, R2, R3 or R4.

The resistance of the thermistor corresponding to the temperature measuring point mark can be calculated by the following formula (2):

It can be understood that by deforming the formula (2), when the resistance value of the thermistor corresponding to the temperature measuring point label is obtained, the analog temperature signal of the thermistor corresponding to the temperature measuring point label can be obtained:

Wherein y is the analog temperature signal of the thermistor corresponding to the temperature measuring point mark.

It should be noted that, by selecting a voltage dividing resistor with a suitable resistance value, such as voltage dividing resistors R1, R2, R3 and R4, the current flowing through the thermistor can be limited, so that the temperature rise of the thermistor is avoided from being too large due to the excessive current, thereby affecting the testing precision, and even possibly causing damage to the thermistor when serious.

In the foregoing condition that the electrode pads 100 are qualified for testing, the controller 123 may also configure the switching combination relationship of the first switch and the second switch in each temperature detection switch unit 121 by using the feature that the temperature sensors 113 are disposed in one-to-one correspondence with the electrode elements 112, so as to identify the electrode pads 100 (the electrode pads 100 are the electrode pads 100 of several electrode elements 112) according to the sampled analog temperature signal of each temperature sensor 113. It should be noted that, the electrode sheet 100 that is acceptable for testing at least includes: all the temperature sensors 113 and their electrical connections are not abnormal, and all the electrode elements 112 and their electrical connections are not abnormal. The type of electrode sheet 100 herein is determined based on the number of electrode elements 112 contained in the electrode sheet 100, for example, the electrode sheet 100 having 20 electrode elements 112 is one type, the electrode sheet 100 having 16 electrode elements 112 is another type, and the electrode sheet 100 having 9 electrode elements 112 is another type.

As shown in fig. 2, under the condition that the electrode sheet 100 is qualified for testing, when the tumor electric field treatment system is initialized, the electric field generator 130 does not transmit the alternating electric signals to the adaptor 120 and the plurality of electrode elements 112 of the electrode sheet 100, and only transmits the direct current power VCC to the corresponding temperature sensors 113 of the adaptor 120 and the electrode sheet 100, so as to avoid the influence of temperature variation on the analog temperature signals detected by the temperature sensors 113 caused by the alternating electric field generated by the alternating electric signals, and the analog temperature signals generated by each temperature sensor 113 of the electrode sheet 100 are approximately the same, and the corresponding actual temperatures and resistances are also approximately the same. For example, the resistances Rt1, rt2, rt3, rt4 and Rt5 of the thermistors corresponding to the temperature measurement points 1,2, 3, 4 and 5 are approximately the same, and the controller 123 can obtain the combined resistances Rt of the five thermistors of the first row group by controlling the first switch K1 and the second switch K9 to be turned on and the other switches to be turned off, because rt=rt1+rt2+rt3+rt4+rt5, and Rt1, rt2, rt3, rt4 and Rt5 are approximately the same, and therefore, rt1 is approximately equal to 5 times, and similarly, the combined resistances of the five thermistors of the second row group, the third row group and the fourth row group are respectively 5 times the resistances of Rt and Rt1, so the number of the electrode elements 112 in the electrode sheet 100 can be calculated, and the electrode sheet 100 with 20 electrode elements 112 can be determined. According to the analog temperature signal obtained by sampling, the actual temperature Tz1 corresponding to each thermistor can be obtained by calculation through the above formula (1), and the actual temperatures Tz2, tz3 and Tz4 of each thermistor in the second row group, the third row group and the fourth row group can be obtained respectively in the same way, and the actual temperatures Tz1, tz2, tz3 and Tz4 are approximately the same and are all approximately the actual temperatures corresponding to Rt 1.

As shown in fig. 2, the controller 123 may also determine whether the abnormal temperature sensor 113 is present in the electrode sheet 100 by configuring the switching combination relationship of each of the first and second switches in each of the temperature detection switching units 121 so as to determine whether the abnormal temperature sensor 113 is present in the electrode sheet 100 based on the analog temperature signal detected by the corresponding one or more combinations of all the temperature sensors 113 of the electrode sheet 100 that are sampled.

As shown in fig. 2, before the electric field generator 130 transmits the alternating electric signals to the adaptor 120 and the plurality of electrode elements 112 of the electrode sheet 100, the direct current power VCC is transmitted to the corresponding temperature sensors 113 of the adaptor 120 and the electrode sheet 100 to operate, so that the influence of temperature change on the analog temperature signals detected by the temperature sensors 113 due to the alternating electric field generated by the alternating electric signals is avoided, the analog temperature signals generated by each temperature sensor 113 (thermistor) of the electrode sheet 100 are approximately the same, and the corresponding actual temperatures and resistances are also approximately the same. I.e. the total resistance value corresponding to the combination of all thermistors of each row group of the same number of thermistors is approximately the same.

And (3) collecting and comparing the total resistance corresponding to the combined thermistors of each row group, for example, controlling the first switch K1 and the second switch K9 to be on, controlling other switches to be off, obtaining the total resistance corresponding to the combined thermistors of the first row group, then controlling the first switch K2 and the second switch K9 to be on, and then controlling other switches to be off, obtaining the total resistance corresponding to the combined thermistors of the second row group, and so on, completing the total resistance corresponding to the combined thermistors of all the row groups, and finally judging whether the total resistance corresponding to the combined thermistors of all the groups is consistent or close to determine whether the thermistors are abnormal. In this process, when the total resistance corresponding to the combination of the five thermistors in each group is approximately the same, each temperature sensor 113 (thermistor) of the electrode sheet 100 is normal. If the total resistance value corresponding to the five thermistors in one row group after being combined is abnormal (different from the total resistance value corresponding to the five thermistors in other rows after being combined), the resistance and the actual temperature of the thermistors corresponding to the marks of each temperature measuring point are obtained in the following manner.

Taking the total abnormal resistance value corresponding to the combined five thermistors in the first row group as an example. The first switch K1 and the second switch K5 are controlled to be turned on, and the other switches are turned off, at the moment, the analog temperature signal of the first thermistor of the first row group is sampled and obtained, the actual temperature T1 of the thermistor can be calculated through the formula (1), and the resistance Rt1 of the thermistor can be calculated through the formula (2).

Then, the first switch K1 and the second switch K6 are controlled to be turned on, and the other switches are turned off, at this time, the analog temperature signals obtained by combining the first thermistor and the second thermistor in the first row group are sampled, the resistance value obtained by combining the first thermistor and the second thermistor, that is, rt1+rt2, can be calculated by using the above formula (2), because rt1 is already obtained, rt2 can be calculated, then the analog temperature signal of the second thermistor can be calculated according to rt2 and the above formula (3), and the analog temperature signal is substituted into the above formula (1) to calculate the actual temperature T2 of the second thermistor.

Then, the first switch K1 and the second switch K7 are controlled to be turned on, and the other switches are turned off, at this time, the analog temperature signals obtained by combining the first to third thermistors of the first row group are sampled, the resistance values obtained by combining the first to third thermistors, that is, rt1+rt2+rt3, can be calculated by using the above formula (2), and since Rt1 and Rt2 have been obtained, rt3 can be calculated, and then the analog temperature signal of the third thermister can be calculated according to Rt3 and the above formula (3), and the actual temperature T3 of the third thermister can be calculated by substituting the analog temperature signal into the above formula (1).

Then, the first switch K1 and the second switch K8 are controlled to be turned on, and the other switches are turned off, at this time, the analog temperature signals of the first to fourth thermistors of the first row group are sampled and obtained, the resistance values of the first to fourth thermistors after being combined, that is, rt1+rt2+rt3+rt4, can be calculated by the above formula (2), and since Rt1, rt2 and Rt3 have been obtained, rt4 can be calculated, and then the analog temperature signal of the fourth thermistor can be calculated according to Rt4 and the above formula (3), and the analog temperature signal is substituted into the above formula (1) to calculate the actual temperature T4 of the fourth thermistor.

Then, the first switch K1 and the second switch K9 are controlled to be turned on, and the other switches are turned off, at this time, the analog temperature signals obtained by combining the first to fifth thermistors of the first row group are sampled, the resistance values obtained by combining the first to fifth thermistors, that is, rt1+rt2+rt3+rt4+rt5, can be calculated by using the above formula (2), and since rt1, rt2, rt3 and rt4 have been obtained, rt5 can be calculated, and then the analog temperature signal of the fifth thermister can be calculated by using the above formula (3) and substituting the analog temperature signal into the above formula (1), the actual temperature T5 of the fifth thermister can be calculated.

Finally, the actual temperatures T1, T2, T3, T4 and T5 of the five thermistors are compared, and if the actual temperature of one thermistor is greatly different from the actual temperatures of other thermistors, the fact that the temperature of the thermistor is abnormal is indicated, so that the abnormal thermistor can be rapidly positioned. In the case of abnormality detection of the temperature sensor 113 (thermistor) by the electrode sheet 100 at the ambient temperature, the actual temperatures T1, T2, T3, T4, and T5 of the five thermistors may be compared with the ambient temperature, and if the actual temperature of one (some) of the thermistors differs greatly from the ambient temperature, the one (some) of the thermistors may be abnormal thermistors.

It should be noted that, if the resistances of all the row groups are normal, that is, the temperatures are normal, the actual temperatures of the thermistors corresponding to the marks of the temperature measuring points can be obtained according to the above manner, that is, the actual temperatures of the thermistors can be obtained by the above manner, and the abnormal thermistors can be found out and positioned quickly in time by simple comparison, and the electrode plate 100 with the abnormal thermistors is found out, so that the quality detection of the electrode plate 100 is facilitated.

Referring to fig. 1, a second connector 150 is provided between the adaptor 120 and the electric field generator 130, the second connector 150 being adapted to connect the electric field generator 130 to the adaptor 120. The adaptor 120 also has a second cable 125. The second connector 150 includes a second plug 151 disposed at an end of the second cable 125 remote from the adaptor 120 and a second socket 152 disposed on the electric field generator 130. The second plug 151 and the second socket 152 are push-on spring connectors, that is, the second connector 150 connects the adaptor 120 and the electric field generator 130 by adopting a connector mode.

Referring to fig. 3, when the electrode pads 100 are four, the second cable is an 8-wire cable, wherein 4 wires are alternating power wires (a 1, a2, a3, and a 4) respectively connected to the four first connectors 40 for providing alternating electric signals of corresponding directions and corresponding polarities, 2 wires are a receiving data line RX and a transmitting data line TX electrically connected to the serial communication unit 124 in the adaptor 120, and the remaining 2 wires are a power wire and a ground wire for providing the direct current power VCC to the at least one temperature sensor 113 of each electrode pad 100. The controller 123 converts the digital temperature signal sampled by the ADC sampling unit 122 and corresponding to the temperature sensor 113 into a digital temperature signal through operation, and the controller 123 controls the serial communication unit 124 to transmit the digital temperature signal to the electric field generator 130 via the second connector 150. That is, the analog temperature signal collected by the ADC sampling unit 122 of the adaptor 120 is converted into a digital temperature signal by the controller 123, and then transferred to the electric field generator 130 via the serial communication unit 124, the transmission data line TX connected to the serial communication unit 124, and the second connector 150. It should be noted that, the controller 123 may also transmit other information such as the type of the electrode pad 100 through the serial communication unit 124, which is not limited herein.

In the above embodiment, by grouping the plurality of electrode elements 112 on the electrode sheet 100, connecting the temperature sensors 113 in the same row group in series, connecting the temperature sensors 113 to the dc power supply through the first switch and the voltage dividing resistor connected in series, connecting the ground terminals 113B of the temperature sensors 113 in the same column group together, and connecting the ground pins GND through the second switch, the sum of the numbers of the first switch and the second switch does not exceed 9, and by configuring the switching timing of the first switch and the second switch so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature sensors 113 of the electrode sheet 100 are sampled, it is possible to achieve 100% coverage of the temperature sensors 113 without increasing the number of cable cores, avoid overstress of the electrode sheet 100, and maintain the application effect of the electrode sheet 100. For example, when the coverage rate of the temperature sensor 113 on the electrode sheet 100 shown in fig. 2 reaches 100%, 22 cores are needed in the related art to achieve the effect, resulting in a thick first cable 115, poor flexibility and poor application effect, while in this embodiment, the coverage rate of the temperature sensor 113 can be ensured to reach 100% without increasing the number of cores of the first cable 115, so that the temperature of each electrode element 112 in the electrode sheet 100 is comprehensively monitored. Meanwhile, by configuring the switching time sequence of the first switch and the second switch so that the analog temperature signals detected by the corresponding one or more combinations in all the temperature sensors 113 of the electrode sheet 100 are respectively sampled, the actual temperature of each temperature sensor 113, namely the actual temperature of the electrode element 112, can be obtained, the electrode element 112 with abnormal temperature can be rapidly positioned, and meanwhile, different electrode sheet 100 types can be distinguished. In addition, because the electrode slice 100 outputs an analog temperature signal, the ADC sampling unit 122 and the like are not arranged on the electrode slice 100, the overall weight of the electrode slice 100 is further reduced, and the application effect of the electrode slice 100 is improved.

In some embodiments, the number of electrode elements 122 of electrode sheet 100 is 9 and arranged in three rows and three columns. The number of temperature sensors 113 in each row group and each column group is 3. The number of first switches is equal to the number of row groups and the number of second switches is equal to the number of column groups. Namely, when the number of the first switches is three, the number of the second switches is three, namely the first switches K1, K2 and K3 and the second switches K4, K5 and K6, the number of the voltage dividing resistors corresponding to the first switches (K1, K2 and K3) is three (R1, R2 and R3), the temperature switching acquisition circuit is 6, and the channels of the ADC sampling unit 122 are 12 (1-3, 4-6, 7-9 and 10-12). It should be noted that, compared to the example shown in fig. 2, the electrode sheets 100 with 9 electrode elements 122 are different in the number of electrode elements 112 and temperature sensors 113, and accordingly, when temperature sampling, temperature anomaly detection, and type determination of the electrode sheets 100 are performed, the total resistance values of all the temperature sensors 113 (thermistors) in each row group are different, and the specific sampling process, the temperature anomaly detection mode, the type determination of the electrode sheets 100, and the like are substantially the same, which will not be described in detail here.

The invention also provides a tumor treatment device, comprising: the electrode sheet 100 described above, or the tumor electric field therapy system 1000 described above.

According to the tumor treatment apparatus of the embodiment of the present invention, through the electrode sheet 100 or the tumor electric field treatment system 1000, the coverage rate of the temperature sensor 113 of 100% can be achieved without increasing the number of the cores of the first cable 115, so that the overload of the electrode sheet 100 is avoided, and the application effect of the electrode sheet 100 is maintained.

The invention also provides a method for detecting the temperature of the electrode plate of the tumor electric field treatment system, wherein the tumor electric field treatment system comprises the electrode plate 100, as shown in fig. 4, and the method comprises the following steps:

S210, the switching sequences of the first switch and the second switch are configured so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature sensors 113 of the electrode pad 100 are respectively sampled, and a digital temperature signal corresponding to each temperature sensor is obtained.

S220, transmitting the digital temperature signal to the electric field generator 130 of the tumor electric field therapy system, such that the electric field generator 130 determines the temperature at each electrode element 112 from the digital temperature signal.

Optionally, under the condition that the electrode sheet 100 is qualified for testing, after obtaining the digital temperature signal corresponding to each temperature sensor, the method further includes: determining a switch combination relation of the first switch and the second switch; the type of the corresponding electrode sheet 100 is identified based on the switch combination relationship of the first switch and the second switch, and the analog temperature signal detected by the corresponding one or more combinations of all the temperature sensors 113 of the sampled electrode sheet 100.

Optionally, under the condition that the number of the temperature sensors 113 in each row group and the number of the temperature sensors 113 in each column group of the electrode sheet 100 are determined, after obtaining the digital temperature signal corresponding to each temperature sensor, the method further includes: determining a switch combination relation of the first switch and the second switch; and judging whether the abnormal temperature sensor 113 exists in the corresponding electrode slice 100 according to the switch combination relation of the first switch and the second switch and the analog temperature signal detected by the corresponding one or more combinations in all the sampled temperature sensors 113 of the electrode slice 100.

According to the electrode slice temperature detection method of the tumor electric field treatment system, the switching time sequences of the first switch and the second switch are configured so that analog temperature signals detected by corresponding one or more combinations in all temperature sensors 113 of the electrode slice 100 are respectively sampled to obtain digital temperature signals, and the digital temperature signals are transmitted to the electric field generator 130 of the tumor electric field treatment system 100, so that the electric field generator 130 determines the temperature of each electrode element 112 according to the digital temperature signals, and the coverage rate of the temperature sensors 113 of 100% can be achieved under the condition that the number of the wire cores of the first cable 115 is not increased, the overload of the electrode slice 100 is avoided, and the pasting effect of the electrode slice 100 is maintained.

The present invention also provides a computer readable storage medium having stored thereon a temperature detection program for the electrode pad 100 of the tumor electric field therapy system 1000, which implements the aforementioned temperature detection method for the electrode pad 100 of the tumor electric field therapy system 1000 when the temperature detection program for the electrode pad 100 of the tumor electric field therapy system 1000 is executed by the controller 123.

According to the computer readable storage medium of the embodiment of the invention, by executing the method for detecting the temperature of the electrode slice 100, the coverage rate of the temperature sensor can be 100% under the condition that the number of the cores of the first cable 115 is not increased, the overload of the electrode slice 100 is avoided, and the application effect of the electrode slice 100 is maintained.

The present invention also provides an adaptor 120 of the tumor electric field therapy system 1000, which comprises a memory (not shown), a controller 123 and an electrode plate 100 temperature detection program of the tumor electric field therapy system 1000 stored in the memory (not shown) and capable of running on the controller 123, wherein the electrode plate 100 temperature detection method of the tumor electric field therapy system 1000 is implemented when the controller 123 executes the electrode plate 100 temperature detection program of the tumor electric field therapy system 1000.

According to the adaptor 120 of the tumor electric field treatment system 1000 of the embodiment of the invention, by executing the foregoing method for detecting the temperature of the electrode slice 100, the coverage rate of the temperature sensor can be 100% without increasing the number of the cores of the first cable 115, so that the overload of the electrode slice 100 is avoided, and the application effect of the electrode slice 100 is maintained.

It should be noted that the logic and/or steps represented in the flow diagrams or otherwise described herein, e.g., a ordered listing of executable instructions for implementing logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, system that includes the controller 123, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). In addition, the computer readable medium may even be paper or other suitable medium on which the program is printed, as the program may be electronically captured, via, for instance, optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner, if necessary, and then stored in a computer memory.

It is to be understood that portions of the present invention may be implemented in hardware, software, firmware, or a combination thereof. In the above-described embodiments, the various steps or methods may be implemented in software or firmware stored in a memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, may be implemented using any one or combination of the following techniques, as is well known in the art: discrete logic circuits having logic gates for implementing logic functions on data signals, application specific integrated circuits having suitable combinational logic gates, programmable Gate Arrays (PGAs), field Programmable Gate Arrays (FPGAs), and the like.

In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

Furthermore, the terms "first," "second," and the like, as used in embodiments of the present invention, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or as implying any particular number of features in the present embodiment. Thus, a feature of an embodiment of the invention that is defined by terms such as "first," "second," etc., may explicitly or implicitly indicate that at least one such feature is included in the embodiment. In the description of the present invention, the word "plurality" means at least two or more, for example, two, three, four, etc., unless explicitly specified otherwise in the examples.

In the present invention, unless explicitly stated or limited otherwise in the examples, the terms "mounted," "connected," and "fixed" as used in the examples should be interpreted broadly, e.g., the connection may be a fixed connection, may be a removable connection, or may be integral, and it may be understood that the connection may also be a mechanical connection, an electrical connection, etc.; of course, it may be directly connected, or indirectly connected through an intermediate medium, or may be in communication with each other, or in interaction with each other. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to specific embodiments.

While embodiments of the present invention have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the invention, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the invention.

Claims

1. An electrode pad for use in a tumor electric field therapy system, comprising:

A plurality of electrode elements, each of which is operable to apply an alternating electric field;

A plurality of temperature sensors, each of the temperature sensors being arranged in correspondence with one of the electrode elements to detect a temperature at the corresponding electrode element, each of the temperature sensors having a signal terminal and a ground terminal, the plurality of temperature sensors being configured in a circuit connection as a plurality of row groups, a plurality of column groups, the corresponding temperature sensors in each of the row groups being connected in series, the ground terminals of the corresponding temperature sensors in each of the column groups being connected together;

whether the abnormal temperature sensor exists in the electrode slice is judged based on temperature signals detected by corresponding one or more combinations in all the sampled temperature sensors of the electrode slice.

2. The electrode pad of claim 1, wherein the corresponding temperature sensors in each of the row groups are connected in series and then connected to a first switch, and the ground terminals of the corresponding temperature sensors in each of the column groups are connected together and then connected to a second switch; whether the abnormal temperature sensor exists in the electrode slice is judged through the configuration of the switch combination relation of the first switch and the second switch and the temperature signals detected by corresponding one or more combinations in all the temperature sensors of the electrode slice sampled based on the switch combination relation of the first switch and the second switch.

3. The electrode pad of claim 2, wherein the corresponding temperature sensors in each of the row groups are connected in series and then connected to a dc power supply through the first switch and the voltage dividing resistor, and the ground terminals of the corresponding temperature sensors in each of the column groups are connected together and then connected to a ground pin through the second switch.

4. The electrode pad of claim 2, further comprising a plurality of diodes, each diode having an anode and a cathode, each diode being disposed in correspondence with a temperature sensor, wherein the ground terminal of the corresponding temperature sensor in each of the column groups is connected to the anode of the corresponding diode and then connected together by the cathode of the corresponding diode to be connected to the corresponding second switch.

5. The electrode pad of claim 1, wherein the temperature sensor is a thermistor.

6. The electrode pad of claim 3, further comprising a substrate, wherein the voltage dividing resistor, the first switch, and the second switch are all disposed outside the substrate.

7. The electrode sheet of claim 1, wherein the electrode element is a dielectric element.

8. The electrode pad of claim 7, wherein the dielectric element is a ceramic pad.

9. Electrode pad according to claim 1, characterized in that each of the electrode elements is provided with a perforation adapted to mount the temperature sensor.

10. The electrode pad of claim 1, wherein a plurality of the electrode elements are connected in parallel to an ac signal line.

11. The electrode sheet according to claim 1, wherein a plurality of the electrode elements are arranged in a plurality of row groups, a plurality of column groups, and the number of the electrode elements of each row group is the same as the number of the temperature sensors, and the number of the electrode elements of each column group is the same as the number of the temperature sensors, on the circuit connection.

12. The electrode sheet according to claim 11, wherein,

The number of the electrode elements is 20, and the electrode elements are arranged in four rows and five columns on the circuit connection; or alternatively

The number of the electrode elements is 9, and the electrode elements are arranged in three rows and three columns on the circuit connection.

13. The electrode sheet of claim 1, wherein a plurality of the electrode elements are arranged in a substantially array in a spatial arrangement.

14. The electrode pad of claim 2, wherein the number of first switches is equal to the number of row groups and the number of second switches is equal to the number of column groups.

15. The electrode pad of claim 2, wherein the sum of the number of the first switch and the second switch is not more than 9.

16. A tumor electric field therapy system, comprising:

at least one pair of electrode sheets according to any one of claims 1-15;

and the controller is used for judging whether the abnormal temperature sensor exists in the corresponding electrode slice or not based on the temperature signals detected by the corresponding one or more combinations of all the sampled temperature sensors of the electrode slice.

17. The oncological electric field therapy system according to claim 16, wherein in case the electrode pads comprise a first switch and a second switch, the controller is further configured to determine whether an abnormal temperature sensor exists in the corresponding electrode pad by configuring a switch combination relationship of the first switch and the second switch and based on a temperature signal detected by a corresponding one or more combinations of all temperature sensors of the electrode pad sampled by the switch combination relationship of the first switch and the second switch.

18. The oncological electric field therapy system according to claim 16, wherein the electrode pads are four.

19. A tumor treatment apparatus, comprising: at least one pair of electrode pads according to any one of claims 1-15, or a oncological electric field therapy system according to any one of claims 16-18.

20. A method for detecting abnormalities of electrode pads for an electric field tumor treatment system, characterized in that the electrode pads are according to any one of claims 1-15, the method comprising:

s210: sampling temperature signals detected by corresponding one or more combinations in all temperature sensors of the electrode plate;

s220: judging whether an abnormal temperature sensor exists in the electrode plate according to the temperature signals detected by each sampled temperature sensor.

21. The method of claim 20, wherein in the case where the electrode pad includes a first switch and a second switch, the step S210 further includes:

the switching time sequences of the first switch and the second switch are configured to sample temperature signals detected by corresponding one or more combinations of all temperature sensors of the electrode plate.

22. The method of claim 21, wherein, in the case of determining the number of the electrode sheet row group temperature sensors and the number of the electrode sheet column group temperature sensors, after step S210, the method further comprises:

23. A computer-readable storage medium, having stored thereon an electrode segment abnormality detection program for a tumor electric field therapy system, which when executed by a controller, implements the electrode segment abnormality detection method for a tumor electric field therapy system according to any one of claims 20 to 22.

24. An adapter for a tumor electric field therapy system, comprising a memory, a controller, and an electrode pad abnormality detection program for a tumor electric field therapy system stored on the memory and operable on the controller, wherein the controller implements the electrode pad abnormality detection method for a tumor electric field therapy system according to any one of claims 20 to 22 when executing the electrode pad abnormality detection program for a tumor electric field therapy system.

25. An electric field generator for a tumor electric field therapy system, comprising a memory, a controller, and an electrode abnormality detection program for a tumor electric field therapy system stored on the memory and operable on the controller, wherein the controller implements the electrode abnormality detection method for a tumor electric field therapy system according to any one of claims 20 to 22 when executing the electrode abnormality detection program for a tumor electric field therapy system.