CN117918341A

CN117918341A - Pesticide suspending agent and preparation method and application thereof

Info

Publication number: CN117918341A
Application number: CN202311777200.3A
Authority: CN
Inventors: 魏亚; 李超; 彭佳; 梅俊豪; 黄鸿良; 张华东
Original assignee: Shenzhen Novozon Crop Science Co ltd
Current assignee: Shenzhen Novozon Crop Science Co ltd
Priority date: 2023-12-21
Filing date: 2023-12-21
Publication date: 2024-04-26

Abstract

The application belongs to the technical field of pesticides, and particularly relates to a pesticide suspending agent, and a preparation method and application thereof. The pesticide suspending agent comprises the following components in percentage by total mass of 100 percent: 1-50% of pesticide active ingredient, 3-15% of biomass-based enzymolysis nano microcrystalline cellulose, 3-10% of emulsifying dispersant, 0.5-5% of wetting agent, 0.1-0.5% of thickener, 2-4% of antifreezing agent, 0.1-0.3% of preservative, 0.1-0.8% of defoamer and the balance of water. The biomass-based nano microcrystalline cellulose is added into the pesticide suspending agent, so that the pesticide liquid is sprayed to form a film on the surface of a plant, and the pesticide liquid spreads uniformly, thereby improving the attachment rate of the pesticide liquid at the target part of the plant. The grain size distribution range of the liquid medicine spray droplets is improved, the drift of the liquid medicine droplets is reduced, the deposition amount of the liquid medicine droplets on plant target positions is increased, the liquid medicine spray droplets are resistant to rain wash after film formation, and the pesticide utilization rate is improved.

Description

Pesticide suspending agent and preparation method and application thereof

Technical Field

The application belongs to the technical field of pesticides, and particularly relates to a pesticide suspending agent, and a preparation method and application thereof.

Background

The pesticide suspending agent is the pesticide preparation which has the fastest development in the pesticide preparation in recent years, more processable pesticide active ingredients, more mature processing technology, lower relative cost and better market prospect. The suspending agent takes water as a medium, and the raw medicine which is insoluble or slightly soluble in water is ground and crushed under the action of the pesticide dispersing wetting agent and other surfactants to form a stable solid-liquid two-phase system with smaller particles, high suspension and better fluidity. The suspending agent basically does not use an organic solvent, has no dust generation in the processing and using processes, and has the characteristics of good environmental compatibility, convenient transportation, convenient use, high safety and the like.

However, the suspending agent only contains a small amount of wetting, dispersing and thickening agents, when the suspending agent product is diluted by water and sprayed on plant leaf surfaces, the surface tension of the diluted solution greatly influences the wetting and spreading of the liquid medicine on the plant leaf surfaces. Because of the variety of plants and targets to be applied, the surface structures are different, and the hydrophilicity and hydrophobicity are also different; for plant targets which are difficult to wet, the liquid medicine of the suspending agent product runs off due to the fact that the suspending agent product cannot be effectively wetted, spread and adhered on the plant surface; the suspending agent product has low drug effect, and the liquid medicine is lost to cause environmental pollution. Meanwhile, when the pesticide is applied in the field, the pesticide is easy to be influenced by weather, and when the pesticide is subjected to strong wind and rain, the pesticide drops are easy to drift, the adhesion capability of the pesticide liquid is poor, the deposition amount is poor, and pesticide particles are easy to evaporate and wash away, so that the pesticide effect and the utilization rate of the pesticide are reduced, and the pesticide effect is poor. Farmers make up and beat pesticides, which is labor-consuming and increases the cost of pesticide application and the environmental risk.

At present, the barrel mixing auxiliary agents such as organic silicon, vegetable oil, mineral oil, polymers, inorganic salts, waxes and the like are methods for increasing wetting and adhesion of liquid medicine, improving fog drop distribution and deposition quantity and further increasing the drug effect, but the barrel mixing auxiliary agents are added into suspending agents to damage the system of the suspending agents and cause unstable formula. Meanwhile, the tank mixing auxiliary agent is inconvenient for farmers to use, the dilution times are difficult to control during use, and risks such as poor using effect and even generation of phytotoxicity are easily caused.

Disclosure of Invention

The application aims to provide a pesticide suspending agent, a preparation method and application thereof, and aims to solve the problems that the existing pesticide suspending agent is uneven in fog drop distribution, drifts in fog drops, is easy to run off of liquid medicine, has poor adhesion with plant targets, has small deposition amount and affects the pesticide effect to a certain extent.

In order to achieve the purposes of the application, the technical scheme adopted by the application is as follows:

In a first aspect, the present application provides a pesticide suspension comprising, based on 100% of the total mass of the pesticide suspension: 1-50% of pesticide active ingredient, 3-15% of biomass-based enzymolysis nano microcrystalline cellulose, 3-10% of emulsifying dispersant, 0.5-5% of wetting agent, 0.1-0.5% of thickener, 2-4% of antifreezing agent, 0.1-0.3% of preservative, 0.1-0.8% of defoamer and the balance of water.

According to the pesticide suspending agent provided by the first aspect of the application, the biomass-based enzymolysis nano microcrystalline cellulose is added, and on one hand, the biomass-based nano microcrystalline cellulose is extracted from a natural biomass base, so that the pesticide suspending agent has the characteristics of wide source, degradability, no pollution and the like; on the other hand, after the biomass-based nano microcrystalline cellulose is added, the pesticide suspending agent can be quickly formed into a film on the surface of a plant after being sprayed, pesticide liquid can be uniformly spread, and the local deposition and the sliding of the pesticide liquid caused by the action of gravity of the pesticide liquid are prevented, so that the attachment rate of the pesticide liquid at the target part of the plant is improved. In addition, the pesticide suspending agent comprising the formula amount of pesticide active ingredient, biomass-based enzymolysis nano microcrystalline cellulose, emulsifying dispersant, wetting agent, thickening agent, antifreezing agent, preservative and defoaming agent improves the particle size distribution range of the spray droplets of the pesticide liquid through the synergistic effect of the components, reduces the drift of the spray droplets of the pesticide liquid, increases the deposition amount of the spray droplets of the pesticide liquid on plant target positions, improves the pesticide utilization rate and reduces the pesticide usage amount. In addition, after the pesticide suspending agent forms a film at the plant target part, the pesticide suspending agent resists rain wash, achieves the effect of permanently protecting plants from being damaged by diseases and insects, does not need repeated medication, saves the cost of manpower and material resources, and also reduces the environmental risk in the pesticide use process.

In a second aspect, the application provides a preparation method of the pesticide suspending agent, which comprises the following steps:

The method comprises the steps of obtaining the effective components of the pesticide in the formula amount, biomass-based enzymolysis nano microcrystalline cellulose, an emulsifying dispersant, a wetting agent, a thickening agent, an antifreezing agent, a preservative, a defoaming agent and water, and carrying out mixing treatment to obtain the pesticide suspending agent.

According to the preparation method of the pesticide suspending agent provided by the second aspect of the application, after the pesticide active ingredient, biomass-based enzymolysis nano microcrystalline cellulose, an emulsifying dispersant, a wetting agent, a thickening agent, an antifreezing agent, a preservative, a defoaming agent and water with the formula amount are obtained, the components are fully and uniformly mixed through mixing treatment, and the pesticide suspending agent is obtained. The preparation process is simple and is suitable for industrial mass production and application. And the biomass-based nano microcrystalline cellulose is added in the prepared pesticide suspending agent, so that the pesticide suspending agent can be quickly formed into a film on the surface of a plant after being sprayed, pesticide liquid can be uniformly spread, and the local deposition and the sliding of the pesticide liquid caused by the action of gravity are prevented, thereby improving the attachment rate of the pesticide liquid at the target part of the plant. Through the synergistic effect of the components, the grain size distribution range of the liquid medicine spray droplets is improved, the drift of the liquid medicine droplets is reduced, the deposition amount of the liquid medicine droplets on plant target positions is increased, the liquid medicine spray droplets are resistant to rain wash after film formation, the pesticide utilization rate is improved, the pesticide use amount is reduced, and the use safety is improved.

In a third aspect, the application provides an application of a pesticide suspending agent, wherein the pesticide suspending agent or the pesticide suspending agent prepared by the method is applied to pest control of crops and/or the forest industry.

The pesticide suspending agent disclosed by the application can be quickly formed into a film on the surface of a plant after being sprayed, is uniformly spread, prevents local deposition and liquid medicine sliding caused by gravity action of the liquid medicine, reduces the drift of liquid medicine fog drops, and increases the deposition amount of the liquid medicine fog drops on a plant target part, so that the liquid medicine attachment rate of the plant target part is improved, the pesticide utilization rate is improved, the pesticide suspending agent is resistant to rain wash after being formed into a film, achieves the effect of permanently protecting the plant from being damaged by diseases and insects, and can be widely applied to disease and insect control of crops and/or forest industries.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments or the description of the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a spray deposition pattern of a pesticide suspension provided in example 1 of the present application;

fig. 2 is a spray deposition pattern of pesticide suspension provided by the control sample of the present application.

Detailed Description

In order to make the technical problems, technical schemes and beneficial effects to be solved more clear, the application is further described in detail below with reference to the embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the application.

In the present application, the term "and/or" describes an association relationship of an association object, which means that three relationships may exist, for example, a and/or B may mean: a alone, a and B together, and B alone. Wherein A, B may be singular or plural. The character "/" generally indicates that the context-dependent object is an "or" relationship.

In the present application, "at least one" means one or more, and "a plurality" means two or more. "at least one of" or the like means any combination of these items, including any combination of single item(s) or plural items(s). For example, "at least one (individual) of a, b, or c," or "at least one (individual) of a, b, and c" may each represent: a, b, c, a-b (i.e., a and b), a-c, b-c, or a-b-c, wherein a, b, c may be single or multiple, respectively.

It should be understood that, in various embodiments of the present application, the sequence number of each process described above does not mean that the execution sequence of some or all of the steps may be executed in parallel or executed sequentially, and the execution sequence of each process should be determined by its functions and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.

The terminology used in the embodiments of the application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this application and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.

The weights of the relevant components mentioned in the embodiments of the present application may refer not only to the specific contents of the respective components but also to the proportional relationship between the weights of the respective components, and thus, it is within the scope of the disclosure of the embodiments of the present application as long as the contents of the relevant components are scaled up or down according to the embodiments of the present application. Specifically, the mass described in the examples of the present application may be a mass unit known in the chemical field such as mu g, mg, g, kg.

The terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated for distinguishing between objects such as substances from each other. For example, a first XX may also be referred to as a second XX, and similarly, a second XX may also be referred to as a first XX, without departing from the scope of embodiments of the application. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature.

The first aspect of the embodiment of the application provides a pesticide suspending agent, which comprises the following components in percentage by mass based on 100% of the total mass of the pesticide suspending agent: 1-50% of pesticide active ingredient, 3-15% of biomass-based enzymolysis nano microcrystalline cellulose, 3-10% of emulsifying dispersant, 0.5-5% of wetting agent, 0.1-0.5% of thickener, 2-4% of antifreezing agent, 0.1-0.3% of preservative, 0.1-0.8% of defoamer and the balance of water.

According to the pesticide suspending agent provided by the embodiment of the application, the biomass-based enzymolysis nano microcrystalline cellulose is added, and on one hand, the biomass-based nano microcrystalline cellulose is extracted from a natural biomass base, so that the pesticide suspending agent has the characteristics of wide source, degradability, no pollution and the like; on the other hand, after the biomass-based nano microcrystalline cellulose is added, the pesticide suspending agent can be quickly formed into a film on the surface of a plant after being sprayed, pesticide liquid can be uniformly spread, and the local deposition and the sliding of the pesticide liquid caused by the action of gravity of the pesticide liquid are prevented, so that the attachment rate of the pesticide liquid at the target part of the plant is improved. In addition, the pesticide suspending agent comprising the formula amount of pesticide active ingredient, biomass-based enzymolysis nano microcrystalline cellulose, emulsifying dispersant, wetting agent, thickening agent, antifreezing agent, preservative and defoaming agent improves the particle size distribution range of the spray droplets of the pesticide liquid through the synergistic effect of the components, reduces the drift of the spray droplets of the pesticide liquid, increases the deposition amount of the spray droplets of the pesticide liquid on plant target positions, improves the pesticide utilization rate and reduces the pesticide usage amount. In addition, after the pesticide suspending agent forms a film at the plant target part, the pesticide suspending agent resists rain wash, achieves the effect of permanently protecting plants from being damaged by diseases and insects, does not need repeated medication, saves the cost of manpower and material resources, and also reduces the environmental risk in the pesticide use process.

The pesticide suspending agent of the embodiment of the application is a preparation with high stability and dispersivity, which is formed by dispersing a liquid pesticide or pesticides in a suspension emulsion, microemulsion, aqueous solvent and other systems containing pesticide active ingredients in water. Wherein the mass percentage of the pesticide active ingredient is 1% -50%, the content of the pesticide active ingredient in the pesticide suspending agent is fully ensured, and the control effect of the pesticide suspending agent on plant diseases and insect pests is ensured. The mass percentage of the added biomass-based enzymolysis nano microcrystalline cellulose is 3-15%, and the content fully ensures the atomization effect of the pesticide suspending agent after dilution and the uniform film forming effect at the plant target position after spraying. If the content of the biomass-based enzymolysis nano microcrystalline cellulose is too low, the film forming effect of the pesticide suspending agent after dilution is poor, and the pesticide deposition amount and the rain wash resistance effect are affected; if the content of the biomass-based enzymolysis nano microcrystalline cellulose is too high, the pesticide suspending agent system is too viscous, false molding is easy to occur, the pourability is poor, the stability is reduced and the like. In addition, the mass percent of the emulsifying dispersant is 3% -10%, the wetting agent is 0.5% -5%, the thickening agent is 0.1% -0.5%, the antifreezing agent is 2% -4%, the preservative is 0.1% -0.3%, and the defoaming agent is 0.1% -0.8%, so that the stability, atomization effect, deposition effect and the like of the pesticide suspending agent are fully ensured.

In some embodiments, the pesticide suspending agent comprises 1% -50%, 5% -40%, 20% -30%, 30% -40% and the like of pesticide active ingredients by mass percent; the mass percentage of the biomass-based enzymolysis nano microcrystalline cellulose can be 3% -15%, 5% -15%, 8% -15%, 10% -15%, 12% -15%, 5-10%, 8-12% and the like; the mass percentage of the emulsifying dispersant can be 3% -10%, 4% -9%, 5% -8%, 6% -10% and the like; the wetting agent can be 0.5% -5%, 1% -3%, 1% -2.5%, 1.5% -2% and the like, the thickener can be 0.1% -0.5%, 0.1%, 0.2%, 0.3%, 0.4%, 0.5% and the like, the antifreezing agent can be 2%, 3%, 4% and the like, the preservative can be 0.1%, 0.2%, 0.3% and the like, and the defoamer can be 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8% and the like.

In some possible implementations, the biomass-based enzymatic nanocrystallite cellulose includes at least one of wood nanocrystallite cellulose, cotton nanocrystallite cellulose, straw nanocrystallite cellulose, bagasse nanocrystallite cellulose, rice hull nanocrystallite cellulose. The biomass-based enzymolysis nano microcrystalline cellulose added into the pesticide suspending agent is used as a novel bio-based functional material, and has excellent mechanical property, huge specific surface area, high crystallinity, good hydrophilicity, high transparency, low density, good biodegradability and biocompatibility and stable chemical property. The biomass-based enzymolysis nano microcrystalline cellulose is combined with pesticide active ingredients to form stable suspension, so that the adhesive force and the penetrating power of the pesticide on the surface of crops can be improved, and the biomass-based enzymolysis nano microcrystalline cellulose has the characteristics of high film forming speed, uniform film forming, high adhesiveness, rain wash resistance and the like, so that the liquid medicine can be quickly formed on the surface of plants, the liquid medicine is uniformly spread, the local deposition of the liquid medicine caused by the action of gravity is prevented, and the risk of phytotoxicity is reduced. Meanwhile, a protective film is formed on the surface of the plant after the liquid medicine is sprayed, so that the liquid medicine can be effectively prevented from sliding off, and the loss rate of the liquid medicine during rain washing is reduced; due to the adhesive property of the film, the drift of fog drops can be reduced, the distribution range of the fog drops is improved, the distribution of the fog drops is more uniform, and the deposition of the fog drops is facilitated; meanwhile, the liquid medicine can be effectively adhered to the plant surface, the liquid medicine adhesion rate of the target part is improved, the medicine carrying amount is improved, the pesticide utilization rate is improved, and crops are permanently protected from being affected by diseases and insect pests. In addition, as the nano microcrystalline cellulose is derived from a plant by-product, the nano microcrystalline cellulose can be completely degraded under natural conditions, no microplastic is produced, the suspending agent itself takes water as a dispersion medium, no organic solvent is contained, the biological and environmental compatibility is good, and the pollution of pesticides to the environment and the harm to human bodies can be reduced. The biomass-based enzymolysis nano microcrystalline cellulose can be directly added into a suspending agent formula for sanding, has no influence on the stability of the formula, avoids damage to a suspension system after other synergistic additives such as organic silicon, vegetable oil, mineral oil, polymers, inorganic salts, waxes and the like are added into the formula, and avoids the occurrence of quality problems such as layering, precipitation, flocculation and the like. In addition, the nano microcrystalline cellulose can also be used as a carrier of the pesticide, and the nano microcrystalline cellulose is combined with the effective components of the pesticide to ensure that the effective components of the pesticide have a slow release effect, prolong the pesticide effect period of the pesticide, reduce the application times and the application amount, and reduce the cost and the labor intensity.

In some possible implementations, the biomass-based enzymatically hydrolyzed nanocrystalline cellulose is selected from the MC-S series provided by shanghai wheat color new materials, inc.

In some possible implementations, the pesticide active ingredient includes at least one of trifloxystrobin, tebuconazole, fluxapyroxad, fluopyram, difenoconazole, prothioconazole, azoxystrobin, pyraclostrobin, chlorantraniliprole, clothianidin. The pesticide components are widely applied to the field of crop pest control, can effectively control the occurrence and spread of diseases and pests, and improve the yield and quality of crops. The trifloxystrobin is a methoxy acrylic acid ester bactericide, has high-efficiency, broad-spectrum, protective, therapeutic, eradicating, penetrating and systemic activities, and shows good activity on almost all fungus diseases. The tebuconazole is a high-efficiency broad-spectrum systemic triazole bactericide, has three functions of protection, treatment and eradication, and has wide bactericidal spectrum and long lasting period. The fluxapyroxad is a novel amide bactericide, has high-efficiency, broad-spectrum and systemic bactericidal activity, and has the protection and treatment effects. Fluopicolide is a pyridine ethyl benzamide fungicide, has a unique action mechanism, has excellent protection and treatment effects, and is not easy to generate drug resistance to bacteria. Difenoconazole is a triazole bactericide, has systemic, protective and therapeutic effects, and has wide bactericidal spectrum and long lasting period. The prothioconazole is a novel triazolethione bactericide, has high-efficiency and broad-spectrum bactericidal activity, has the protection and treatment effects, and is not easy to generate drug resistance to bacteria. The azoxystrobin is a methoxy acrylic bactericide, has high-efficiency and broad-spectrum bactericidal activity, has protection and treatment effects, and has long lasting period. Pyraclostrobin is one new kind of methoxy acrylate bactericide with the functions of protecting, treating, eliminating, penetrating and sucking, and has wide bactericidal spectrum and long lasting period. The chlorantraniliprole is a novel amide pesticide, has high-efficiency and broad-spectrum insecticidal activity, and mainly acts on a ryanodine receptor of pests, so that the pests have muscle movement disorder and paralysis and finally die. Clothianidin is a novel nicotinic pesticide with high-efficiency and broad-spectrum insecticidal activity, and mainly acts on the nervous system of pests, so that the pests are excited, spasmodic and paralyzed, and finally die.

In some possible implementations, the emulsifying dispersant includes at least one of fatty alcohol polyoxyethylene ether phosphate, sodium lignin sulfonate, polycarboxylate, EO-PO block polyether, polyoxyethylene polyoxypropylene ether copolymer; the function of the emulsifying dispersant in the pesticide is mainly to help the pesticide to better permeate to the plant surface and improve the control effect. Meanwhile, the stability and the suspension degree of the pesticide can be improved, the loss of the pesticide liquid is reduced, and the utilization rate of the pesticide is improved. The fatty alcohol polyoxyethylene ether phosphate is used as an emulsifier and a dispersing agent, so that the solubility and stability of the pesticide can be improved, the pesticide can be better permeated to the surfaces of plant leaves, and the control effect is improved. The sodium lignin sulfonate has better emulsifying, dispersing, suspending and stabilizing properties, can be used as a dispersing agent and a suspending agent of pesticides, improves the suspension degree and stability of the pesticides, reduces the loss of liquid medicine and improves the control effect. The polycarboxylate is a high-performance dispersing agent and emulsifying agent, can help pesticides to better disperse and permeate to the plant surface, and improves the control effect. The EO-PO block polyether is a high-efficiency emulsifying agent and dispersing agent, and can help pesticides to better permeate to the surfaces of plant leaves, and the control effect is improved. The polyoxyethylene polyoxypropylene ether copolymer is a high-performance emulsifier and dispersant, can help pesticides to better disperse and permeate to plant surfaces, and improves the control effect. Meanwhile, the emulsifying dispersant can also improve the stability of pesticides and prolong the pesticide effect period.

In some possible implementations, the wetting agent includes at least one of alkylphenol ethoxylates, isopolyoxyethylene ethers, sodium 5, 6-dibutylnaphthalene-2-sulfonate; the wetting agents can help pesticides to better permeate to the plant surface, and the control effect is improved; meanwhile, the stability and the suspension degree of the pesticide can be improved, the loss of the pesticide liquid is reduced, and the utilization rate of the pesticide is improved. Wherein, alkylphenol ethoxylates (APEO) can better disperse and permeate pesticides on plant surfaces, thereby improving the control effect. The isomeric alcohol polyoxyethylene ether (ISO) can improve the solubility and stability of components in the pesticide, help the pesticide to better permeate the surfaces of plant leaves, and improve the control effect. The 5, 6-dibutyl naphthalene-2-sodium sulfonate (DBS) can help the pesticide to better permeate the plant surface, and the control effect is improved. Meanwhile, the wetting agents can also improve the stability and suspension degree of pesticides, reduce the loss of liquid medicine and improve the utilization rate of the pesticides.

In some possible implementations, the thickener includes at least one of xanthan gum, magnesium aluminum silicate; the thickening can make the pesticide suspending agent more stable and effective, thereby improving the using effect and efficiency of the pesticide. The xanthan gum is used as a thickening agent, and can adjust the viscosity of the system, so that sedimentation of raw pesticide particles in the storage process is reduced, and the suspension stability of the pesticide suspending agent is improved. The magnesium aluminum silicate in the pesticide suspending agent can improve the stability and the anti-sedimentation capability of the suspending agent, increase the adhesiveness of the pesticide on the surface of crops, and improve the effect and the durability of the pesticide. In addition, the dispersibility and the solubility of the pesticide can be increased, the adhesiveness and the permeability of the pesticide can be increased, and the viscosity and the rheological property of the suspending agent can be influenced.

In some possible implementations, the antifreeze includes at least one of ethylene glycol, propylene glycol, glycerol; the antifreezing agents cooperate with other components in the pesticide suspending agent, so that the pesticide suspending agent can be ensured to be kept stable within a wider temperature range, and the control effect and the use safety of the pesticide suspending agent are ensured. Wherein, the glycol can lower the freezing point of the system and help prevent the pesticide suspending agent from freezing at low temperature. Propylene glycol can lower the freezing point of the system and improve the stability of the pesticide suspending agent. Glycerol, namely glycerin, has an antifreezing effect due to the special molecular structure, reduces the freezing point of the system, and ensures that the pesticide suspending agent does not freeze at low temperature.

In some possible implementations, the preservative includes at least one of 1,2 benzisothiazolin-3-one, isothiazolinone, sodium benzoate; the function of the preservatives in the pesticide suspending agent is mainly to inhibit the growth of microorganisms and maintain the stability and effectiveness of the pesticide suspending agent. Wherein, 1,2 benzisothiazolin-3-one (BIT) has good inhibition effect on bacteria, mold, microzyme and other microorganisms. In the pesticide suspending agent, the shelf life of the product can be effectively prolonged, and the deterioration of the suspending agent caused by microbial contamination can be prevented. Isothiazolinones (MIT) have a very good inhibitory effect on various microorganisms. In the pesticide suspending agent, MIT can effectively inhibit the growth of microorganisms such as bacteria, mould and the like, and the stability and the effectiveness of the suspending agent are maintained. The sodium benzoate is mainly used for inhibiting the growth of bacteria and mould, and can play a role in corrosion prevention and prevent the pesticide suspending agent from being polluted by microorganisms in the storage and use processes.

In some possible implementations, the defoamer includes at least one of a modified polyether silicone-based defoamer. Modified polyether silicone-based defoamers typically include: polyether modified silicone defoamers, polyether polysiloxane copolymers, polyether silanes, and the like. In pesticide suspending agents, the modified polyether silicone defoamer can reduce or prevent foam formation, and the foam is rapidly dissipated by reducing the surface tension of the liquid and destroying the stability of the foam. Thus, the foam problem of the pesticide suspending agent in the manufacturing and using processes can be reduced, and the control effect and the utilization rate of the pesticide are improved.

In some possible implementations, the particle size of the material in the pesticide suspension is less than 5 μm. The small-particle-size materials in the suspending agent can better ensure the spraying effect of the pesticide suspending agent and ensure the tiny and uniform fog drops.

In a second aspect, an embodiment of the present application provides a method for preparing the pesticide suspension agent, including the following steps:

S10, obtaining the effective components of the pesticide in the formula amount, biomass-based enzymolysis nano microcrystalline cellulose, an emulsifying dispersant, a wetting agent, a thickening agent, an antifreezing agent, a preservative, a defoaming agent and water, and mixing the components to obtain the pesticide suspending agent.

According to the preparation method of the pesticide suspending agent, the pesticide suspending agent is obtained by mixing the components after the formula amount of the pesticide active ingredient, the biomass-based enzymolysis nano microcrystalline cellulose, the emulsifying dispersant, the wetting agent, the thickening agent, the antifreezing agent, the preservative, the defoamer and the water are obtained. The preparation process is simple and is suitable for industrial mass production and application. And the biomass-based nano microcrystalline cellulose is added in the prepared pesticide suspending agent, so that the pesticide suspending agent can be quickly formed into a film on the surface of a plant after being sprayed, pesticide liquid can be uniformly spread, and the local deposition and the sliding of the pesticide liquid caused by the action of gravity are prevented, thereby improving the attachment rate of the pesticide liquid at the target part of the plant. Through the synergistic effect of the components, the grain size distribution range of the liquid medicine spray droplets is improved, the drift of the liquid medicine droplets is reduced, the deposition amount of the liquid medicine droplets on plant target positions is increased, the liquid medicine spray droplets are resistant to rain wash after film formation, the pesticide utilization rate is improved, the pesticide use amount is reduced, and the use safety is improved.

In some possible implementations, in step S10, the step of mixing includes: after carrying out first mixing shearing treatment on 30-80 wt% of an emulsifying dispersant, a wetting agent, a preservative, biomass-based enzymolysis nano microcrystalline cellulose, a defoaming agent and water, adding an effective pesticide component and a thickening agent to carry out second mixing shearing treatment and grinding treatment, and adding an antifreezing agent and the balance of the defoaming agent to carry out mixing and stirring to obtain the pesticide suspending agent. Under the condition of the mixing step, the components can be fully and uniformly mixed, and the dispersion stability of the pesticide suspending agent can be ensured.

In some possible implementations, the rotational speed conditions of the first and second mixed shear treatments are 2000-3000 rpm; the duration is 10 to 60 minutes. Specifically, 30-80 wt% of emulsifying dispersant, wetting agent, preservative, biomass-based enzymolysis nano microcrystalline cellulose, defoamer and water are circularly sheared and mixed for 10-20 minutes at the rotating speed of 2000-3000 rpm below 30 ℃, then the pesticide active ingredient and thickener are added, the materials in the slurry are circularly sheared and mixed for 30-60 minutes at the rotating speed of 2000-3000 rpm, and then the materials in the slurry are grinded, processed and refined, and then the antifreezing agent and the rest defoamer are added for mixing and stirring for 30-60 minutes, so that the pesticide suspending agent is obtained.

In some possible implementation modes, zirconia beads with the particle size of 0.6-0.8 mm are adopted for grinding treatment, so that mixed grinding of all component materials in the pesticide suspending agent can be fully ensured under the grinding condition, the particle size of the ground materials is smaller than 5 mu m, and the stability of the suspending agent is further improved.

In a third aspect, an embodiment of the present application provides an application of a pesticide suspension, where the pesticide suspension or the pesticide suspension prepared by the method is applied to pest control in crops and/or forest industries.

In some embodiments, the crop comprises a food crop, such as: wheat, corn, rice, sorghum, millet, and the like; commercial crops, such as: oil crops, vegetable crops, flowers, grasses, trees, etc.

In some embodiments, the pesticide suspending agent is specifically applied to the prevention and treatment fields of rice blast, citrus sandy skin disease and the like.

In order that the above-mentioned implementation details and operation of the present application may be clearly understood by those skilled in the art, and that the present application may be significantly embodied in the advanced performance of the pesticide suspension agent and the preparation method thereof, the above-mentioned technical solutions will be exemplified by a plurality of examples.

Example 1

42% Trifloxystrobin tebuconazole suspending agent (14% + 28%), comprising the following components in percentage by mass:

The preparation method comprises the following steps:

According to the composition of the formula, 70% of water, 3% of emulsified dispersant fatty alcohol polyoxyethylene ether phosphate, 1% of emulsified dispersant polycarboxylate, 1% of wetting agent alkylphenol ethoxylate, 0.25% of preservative isothiazolinone, 8% of wood nano microcrystalline cellulose, 0.2% of modified polyether organic silicon defoamer are circularly sheared and mixed for 10 minutes at the rotating speed of 2500 rpm, then 14% of trifloxystrobin raw material, 28% of tebuconazole raw material and 0.15% of thickener xanthan gum are added, circularly sheared and mixed for 30 minutes at the rotating speed of 2500 rpm to obtain uniform mixed solution, zirconia beads with the particle size of 0.6-0.8 mm are added for sanding, when the particle size of the detected sanding solution is smaller than 5 mu m, discharging is carried out, then 4% of antifreeze glycol, 0.2% of modified polyether organic silicon defoamer and the rest 30% of water are added for mixing and stirring for 30 minutes, and 42% of trifloxystrobin and tebuconazole suspending agent can be prepared.

Example 2

35% Difenoconazole and azoxystrobin suspending agent (20% +15%), comprising the following components in percentage by mass:

The preparation method comprises the following steps:

According to the composition of the formula, 65% of water, 3% of an emulsifying dispersant EO-PO block polyether, 1% of an emulsifying dispersant polycarboxylate, 1% of a wetting agent alkylphenol ethoxylate, 0.2% of a preservative 1, 2-benzisothiazolin-3-one, 10% of wood nano microcrystalline cellulose, 0.2% of a modified polyether organic silicon defoamer, and the like are circularly sheared and mixed for 10 minutes at a rotating speed of 2500 revolutions per minute at a temperature of below 30 ℃, then 20% of a difenoconazole original drug, 15% of an azoxystrobin original drug and 0.13% of a thickener xanthan gum are added, circularly sheared and mixed for 30 minutes at the rotating speed of 2500 revolutions per minute, a uniform mixed solution is obtained, zirconium oxide beads with a particle size of 0.6mm-0.8mm are added for sanding, when the particle size of the sanding solution is detected to be smaller than 5 mu m, discharging is carried out, and then 4% of an antifreezing agent propylene glycol, 0.2% of a modified polyether organic silicon defoamer and the rest 35% of water are added for mixing and stirring for 30 minutes, so that the 35% difenoconazole suspending agent is obtained.

Example 3

A25% pyraclostrobin suspending agent comprises the following components in percentage by mass:

The preparation method comprises the following steps:

According to the composition of the formula, 60% of water, 4% of an emulsifying dispersant EO-PO block polyether, 2% of an emulsifying dispersant polycarboxylate, 1% of a wetting agent isomeric alcohol polyoxyethylene ether, 0.2% of a preservative 1, 2% of benzisothiazolin-3-one, 12% of cotton nano microcrystalline cellulose, 0.2% of a modified polyether organic silicon defoamer, controlling the temperature below 30 ℃, circularly shearing and mixing for 10 minutes at a rotating speed of 2500 revolutions per minute, then adding 25% of a pyraclostrobin raw material, 0.18% of a thickener xanthan gum and 0.3% of a thickener magnesium aluminum silicate, circularly shearing and mixing for 30 minutes at a rotating speed of 2500 revolutions per minute, obtaining a uniform mixed solution, adding 0.6-0.8 mm of zirconia beads for sanding, discharging when the particle size of the detected sanding solution is smaller than 5 mu m, adding 4% of an antifreezing agent glycerol, 0.2% of a modified polyether organic silicon defoamer, and the remaining 40% of water, and mixing and stirring for 30 minutes, thus obtaining the 25% pyraclostrobin suspension.

Example 4

A40% chlorantraniliprole suspending agent comprises the following components in percentage by mass:

The preparation method comprises the following steps:

According to the composition of the formula, 70% of water, 5% of an emulsifying dispersant polyoxyethylene polyoxypropylene ether copolymer, 1.5% of a wetting agent 5, 6-dibutyl naphthalene-2-sodium sulfonate, 1% of a wetting agent isomeric alcohol polyoxyethylene ether, 0.2% of a preservative 1,2 benzisothiazolin-3-one, 10% of straw nanocrystalline cellulose, 0.2% of a modified polyether organic silicon defoamer are circularly sheared and mixed for 10 minutes at a rotating speed of 2500 revolutions per minute at a temperature of 30 ℃ or below, then 10% of chlorantraniliprole original medicine, 30% of clothianidin original medicine, 0.2% of a thickener xanthan gum and 0.3% of thickener magnesium aluminum silicate are added, the mixture is circularly sheared and mixed for 30 minutes at a rotating speed of 2500 revolutions per minute to obtain uniform mixed liquid, zirconium oxide beads of 0.6mm-0.8mm are added for sanding, when the particle size of the detected sanding liquid is smaller than 5 mu m, discharging is carried out, and then 4% of antifreeze ethylene glycol, 0.2% of modified polyether organic silicon defoamer and the rest 30% of water are added for 30% of chlorantraniliprole are circularly sheared and mixed for 30 minutes, so that the chlorantraniliprole suspension can be prepared.

Example 5

A40% fluxapyroxad-tebuconazole suspending agent comprises the following components in percentage by mass:

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The preparation method comprises the following steps:

according to the composition of the formula, 65% of water, 3% of an emulsifying dispersant polyoxyethylene polyoxypropylene ether copolymer, 1% of an emulsifying dispersant polycarboxylate, 1% of a wetting agent isomeric alcohol polyoxyethylene ether, 0.2% of a preservative 1, 2-benzisothiazolin-3-one, 3% of wood nano microcrystalline cellulose, 0.2% of a modified polyether organic silicon defoamer, and the like are circularly sheared and mixed for 10 minutes at a rotating speed of 2500 revolutions per minute at a temperature of below 30 ℃, then 10% of a fluxapyroxad raw material, 30% of a tebuconazole raw material and 0.15% of a thickener xanthan gum are added, circularly sheared and mixed for 30 minutes at a rotating speed of 2500 revolutions per minute, a uniform mixed solution is obtained, zirconia beads with a particle size of 0.6-0.8 mm are added for sanding, when the particle size of the sanding solution is detected to be smaller than 5 mu m, discharging is carried out, and then 4% of an antifreezing agent propylene glycol, 0.2% of a modified polyether organic silicon defoamer and the rest 35% of water are added for mixing and stirring for 30 minutes, so that the 40% of fluxad tebuconamide/tebuconazole suspension is obtained.

Example 6

420 G/prothioconazole/fluopyram (26% + 13%) suspending agent comprises the following components in percentage by mass:

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The preparation method comprises the following steps:

According to the composition of the formula, 80% of water, 3% of emulsifying dispersant polycarboxylate, 1% of emulsifying dispersant lignin sulfonate sodium salt, 1% of wetting agent 5, 6-dibutyl naphthalene-2-sodium sulfonate, 0.3% of preservative sodium benzoate, 15% of bagasse nano microcrystalline cellulose, 0.2% of modified polyether organic silicon defoamer, controlling the temperature below 30 ℃, circularly shearing and mixing for 10 minutes at the rotating speed of 2500 revolutions per minute, then adding 26% of prothioconazole technical material, 13% of fluopyram technical material, 0.1% of thickener xanthan gum, circularly shearing and mixing for 30 minutes at the rotating speed of 2500 revolutions per minute to obtain uniform mixed solution, adding zirconia beads with the particle size of 0.6-0.8 mm for sanding, discharging when the particle size of the sanding solution is detected to be smaller than 5 mu m, then adding 4% of antifreeze propylene glycol, 0.2% of modified polyether organic silicon defoamer and the rest 20% of water for mixing and stirring for 30 minutes, and obtaining 420 g/prothioconazole and fluopyram suspension.

Further, to verify the advancement of the embodiments of the present application, the following performance tests were performed:

1. The pesticide suspension provided in examples 1 to 6 above were measured for each of the performance parameters of mass fraction/%, pH range, suspension rate/%, pourability/%, persistent foam (after 1 min)/ml, wet sieve test (passing 75 μm test sieve)/%, low temperature stability (0 ℃ + -2 ℃)/7 d, thermal storage stability (54 ℃ + -2 ℃)/14 d, etc. The measurement results are shown in tables 1 to 4 below, respectively:

table 1 42% trifloxystrobin tebuconazole suspension provided in example 1

Table 2 example 2 provides a 35% difenoconazole azoxystrobin suspension concentrate

TABLE 3 25% pyraclostrobin suspension provided in example 3

Table 4 example 4 provides a 40% chlorantraniliprole suspension concentrate

Table 5 40% fluxapyroxad tebuconazole suspension provided in example 5

TABLE 6 420g/L Prosulfazole fluopyram suspension provided in EXAMPLE 6

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As shown in the test results of the tables 1-6, the pesticide suspending agent provided by the embodiment of the application has the characteristics of good mass fraction/%, pH value range, trifloxystrobin suspension rate/%, tebuconazole suspension rate/%, pourability/%, lasting foam (after 1 min)/ml, wet screening test (passing 75 μm test screen)/ml, low temperature stability (0+/-2 ℃) and 7d, thermal storage stability (54+/-2 ℃) and 14 d.

2. For the 42% trifloxystrobin tebuconazole suspension provided in example 1 of the present application, the fog drop distribution range, the deposition performance after film formation and the rainfastness performance were tested, and the control sample was 42% trifloxystrobin tebuconazole suspension of nopilene crop science co.

The method for testing the distribution range of the fog drops comprises the following steps: the liquid medicine was diluted 30 times by simulating the concentration of the anti-flight agent, and tested by using a Baite 2000S and indoor fog drop evaluation system, the spraying pressure was set to 0.03mpa, the spray head model was 110-01, and the fog drop distribution test results are shown in Table 7:

TABLE 7

Sample of	DV(10)/μm	DV(50)/μm	DV(90)/μm
				Example 1	125.28	276.57	422.36
Control sample	92.37	200.48	320.15

Wherein DV (10/50/90) is the number of sampling fog drops and accumulates according to the volume order of the fog drops, and the accumulated value is the fog drop diameter corresponding to (10/50/90) of the sum of the number of the sampling fog drops. From the test table, the mist distribution of the embodiment 1 of the application is obviously better than that of a control sample, the number of small mist drops is less, the mist distribution is uniform, the evaporation and the drift of the mist drops can be reduced, and the number of the mist drops deposited on a target is increased.

3. Deposition performance testing method: the chemical liquid is diluted by 30 times by simulating the concentration of the anti-pesticide application, and is sprayed by using a 3WP-2000 type walking spray tower of Nanjing agricultural machinery in rural agricultural, and the 42% trifloxystrobin tebuconazole suspending agent provided in the example 1 and the 42% trifloxystrobin tebuconazole suspending agent of the control sample are uniformly sprayed on a M1 glass sheet which is dried and weighed in advance, wherein the glass sheet simulates the natural sagging of the blade, and the glass sheet is placed in the spray tower at 45 degrees. After spraying, air-dried naturally for 1 hour, the mass is weighed as M2, the deposition amount g=m2-M1, the test pictures are shown in fig. 1 and 2, and the deposition amount data are shown in the following table 8:

TABLE 8

Sample of	Deposition amount (mg)
		Example 1	1.04
Control sample	0.53

From the above test results, the deposition amount of example 1 of the present application is significantly better than that of the control sample, and the deposition amounts are respectively: the deposition amount of example 1 is 1.04mg, the deposition amount of the control sample is 0.53mg, the deposition amount is improved by about 50% compared with the control sample, and meanwhile, as can be seen from the deposition attached figures 1 and 2, after spraying of example 1, the distribution and the spreading are more uniform and the adhered liquid medicine is more due to the effect of biomass-based enzymolysis nano microcrystalline cellulose.

4. The rain wash resistance test was continued for the above example 1 and the control sample, test method: and (3) placing the air-dried glass sheet after spraying into a spraying tower, simulating a rainfall process, flushing for 6 times by using 50ml of water, naturally air-drying for 1 hour after flushing, weighing, and calculating the liquid medicine loss rate. The test results are shown in table 9 below:

TABLE 9

Sample of	Loss rate (%)
		Example 1	23.16
Control sample	78.15

The results show that the liquid medicine loss rates are respectively as follows: example 1 was 23.16% and the control sample was 78.15%, indicating that example 1 has good rain wash resistance, significantly better than the control sample.

5. The 42% trifloxystrobin tebuconazole suspension provided in example 1 of the present application was tested for activity against rice blast and citrus fruit blotch pathogens, and the control sample was 42% trifloxystrobin tebuconazole suspension from nopilex crop science co. The test results are shown in tables 10 and 11 below:

TABLE 10 results of indoor Activity assay of example 1 and control samples against Pyricularia oryzae

Test agent	Toxicity regression equation	EC₅₀(mg/L)	EC₉₀(mg/L)	95% Confidence limit	Correlation coefficient
						Control sample	y＝0.8790x+5.29	0.4771	13.52	0.3323-0.6680	0.9917
Example 1	y＝0.8285x+5.55	0.2140	7.54	0.1032-0.4438	0.9688

TABLE 11 results of indoor Activity assay of example 1 and control samples against Alternaria citrifolia

Test agent	Toxicity regression equation	EC₅₀(mg/L)	EC₉₀(mg/L)	95% Confidence limit	Correlation coefficient
						Control sample	y＝0.4486x+5.00	1.0211	733.61	0.6439-1.6193	0.9683
Example 1	y＝0.4693x+5.11	0.5690	306.27	0.4192-0.7722	0.9771

The test results show that EC ₅₀ (mg/L) of the example 1 and the control sample on Pyricularia oryzae is 0.2140 and 0.4771 respectively; EC ₅₀ (mg/L) against Celastrus citri were 0.5690 and 1.0211, respectively, and the effect of example 1 was significantly better than that of the control sample, with an activity increase of about 50%. The 42% trifloxystrobin tebuconazole suspending agent provided by the embodiment 1 of the application has obviously better indoor activities on rice blast and citrus sand skin bacteria than the conventional 42% trifloxystrobin tebuconazole suspending agent of a control sample.

In conclusion, the pesticide suspending agent prepared by the embodiment of the application can quickly form a film on the surface of a plant after being sprayed, the pesticide liquid is uniformly spread, the local deposition of the pesticide liquid caused by the action of gravity and the sliding of the pesticide liquid are prevented, the attachment rate of the pesticide liquid at a target part is improved, the rain erosion resistance is realized, the distribution range of fog drops is improved, the drifting is reduced, the deposition amount is increased, the pesticide utilization rate is improved, and the effect of permanently protecting the plant from being damaged by diseases and insects is achieved; meanwhile, the pesticide suspending agent prepared by the application has excellent formula stability, application safety and convenient usability.

The foregoing description of the preferred embodiments of the application is not intended to be limiting, but rather is intended to cover all modifications, equivalents, and alternatives falling within the spirit and principles of the application.

Claims

1. A pesticide suspending agent, which is characterized by comprising the following components by taking the total mass of the pesticide suspending agent as 100 percent: 1-50% of pesticide active ingredient, 3-15% of biomass-based enzymolysis nano microcrystalline cellulose, 3-10% of emulsifying dispersant, 0.5-5% of wetting agent, 0.1-0.5% of thickener, 2-4% of antifreezing agent, 0.1-0.3% of preservative, 0.1-0.8% of defoamer and the balance of water.

2. The pesticide suspension of claim 1, wherein the biomass-based enzymatically hydrolyzed nano-microcrystalline cellulose comprises at least one of wood nano-microcrystalline cellulose, cotton nano-microcrystalline cellulose, straw nano-microcrystalline cellulose, bagasse nano-microcrystalline cellulose, rice hull nano-microcrystalline cellulose.

3. A pesticide suspension as set forth in claim 2, wherein said biomass-based enzymatically hydrolyzed nanocrystallite cellulose is selected from the MC-S series provided by shanghai mai new materials inc.

4. The pesticide suspension of claim 1, wherein the pesticide active ingredient comprises at least one of trifloxystrobin, tebuconazole, fluxapyroxad, fluopyram, difenoconazole, prothioconazole, azoxystrobin, pyraclostrobin, chlorantraniliprole, clothianidin.

5. The pesticidal suspension of any one of claims 1-4, wherein said emulsifying dispersant comprises at least one of fatty alcohol polyoxyethylene ether phosphate, lignin sulfonate sodium salt, polycarboxylate, EO-PO block polyether, polyoxyethylene polyoxypropylene ether copolymer;

and/or the wetting agent comprises at least one of alkylphenol ethoxylates, isomeric alcohol polyoxyethylene ethers and 5, 6-dibutyl naphthalene-2-sodium sulfonate;

And/or the thickener comprises at least one of xanthan gum and magnesium aluminum silicate;

and/or the antifreezing agent comprises at least one of ethylene glycol, propylene glycol and glycerol;

And/or the preservative comprises at least one of 1,2 benzisothiazolin-3-one, isothiazolinone and sodium benzoate;

And/or the defoamer comprises at least one of modified polyether silicone defoamers.

6. A pesticide suspension according to claim 5, wherein the particle size of the material in the pesticide suspension is less than 5 μm.

7. A method of preparing a pesticide suspension as claimed in any one of claims 1 to 6 comprising the steps of:

8. The method of preparing a pesticide suspension according to claim 7, wherein the step of mixing treatment comprises: and (3) performing first mixing shearing treatment on the emulsifying dispersant, the wetting agent, the preservative, 30-80 wt% of the biomass-based enzymolysis nano microcrystalline cellulose, the defoamer and water, adding the pesticide active ingredient and the thickener, performing second mixing shearing treatment and grinding treatment, and adding the antifreezing agent and the balance of the defoamer, and performing mixing stirring to obtain the pesticide suspending agent.

9. The method for preparing a pesticide suspension according to claim 8, wherein the grinding treatment adopts zirconia beads with the particle size of 0.6-0.8 mm, and the grinding treatment is carried out until the particle size of the material is less than 5 μm;

and/or the rotating speed conditions of the first mixed shearing treatment and the second mixed shearing treatment are 2000-3000 rpm; the duration is 10 to 60 minutes.

10. The use of a pesticide suspension according to any one of claims 1 to 6 or prepared by a method according to any one of claims 7 to 9 for controlling pests in the crop and/or wood industry.