CN1178678C - Process for preparing arnebia root medicine with broad-spectrum medical functions - Google Patents
Process for preparing arnebia root medicine with broad-spectrum medical functions Download PDFInfo
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- CN1178678C CN1178678C CNB011041587A CN01104158A CN1178678C CN 1178678 C CN1178678 C CN 1178678C CN B011041587 A CNB011041587 A CN B011041587A CN 01104158 A CN01104158 A CN 01104158A CN 1178678 C CN1178678 C CN 1178678C
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Abstract
The present invention relates to a process for preparing a gromwell preparation of a traditional Chinese medicine extract with broad-spectrum medical functions. The gromwell preparation adopts edible wine as solvents, and gromwell oral liquid is prepared by a simple technology. The gromwell preparation solves the problems that the medicinal ingredient of the existing similar alkannin medicine is single, or the existing similar alkannin medicine is difficult to administer; the medicinal ingredients of the gromwell preparation are enriched; the synergistic mechanism is strengthened, and the treating range of the gromwell preparation is extended. The gromwell preparation is mainly used for treating inflammation and cancer, reducing fat, reducing blood sugar, invigorating the kidney and preventing senility.
Description
The present invention relates to a kind of preparation method of Chinese medicine extract Radix Arnebiae (Radix Lithospermi) agent of broad-spectrum medical functions.
The medical functions of Chinese medicine Radix Arnebiae (Radix Lithospermi) is on the books in Shennong's Herbal, and be collected in China's pharmacopeia, about various folk prescriptions, compound recipe and the side of one-tenth of Radix Arnebiae (Radix Lithospermi) has tens kinds approximately, relate to kind surplus the disease 30 of can curing the disease, major function is removing heat from blood, invigorate blood circulation, convergence, rash, heat clearing away, detoxify and control cancer etc.Be applicable to heat in blood poison Sheng, the macule purple is black, fiber crops are examined saturating, treatment of conditions such as skin ulcer is burst, eczema, burn due to hot liquid or fire.Show that according to modern medicine science and technology achievement in research shikonin that contains in the Radix Arnebiae (Radix Lithospermi) and derivant thereof are naphthaquinone, account for the 0.8-5.6% of crude drug.On the pharmacology, this composition has the effect of transmitting electronics in vivo in the redox reaction, has antibiotic, antiinflammatory, antiviral, anticancer physiologically active.
At present, the great attention that the further investigation and the extensive use of Radix Arnebiae (Radix Lithospermi) naphthoquinone is subjected to domestic and international the world of medicine, but no matter the existing process of extracting the Radix Arnebiae (Radix Lithospermi) naphthoquinone is that decocting is fried, or industrial extraction method and biological synthesis process, weak point is all arranged.As traditional Chinese medicine decocting method, water insoluble because the Radix Arnebiae (Radix Lithospermi) naphthoquinone is slightly soluble in hot water, be soluble in alcohol and fat.Therefore to obtain medicinal component few for decocting method, and curative effect is poor naturally, and the difficult clothes of flavour of a drug, is difficult for preservation; And for example fried extraction, generally all use rough Oleum Glycines, Oleum sesami and Oleum Arachidis hypogaeae semen is solvent because during impurity bands such as the impure contained fat of oil, glue, acid are used as medicine, put for a long time and be flocculent deposit, when oral sense greasy with the foreign odor flavour of a drug; Especially be very worthless with the method extraction Chinese medicine medicinal component that Western medicine is purified modern age usually, seriously destroyed the association composition and the comprehensive cooperative effect of Chinese medicine.As organic solvent method of purification and biological synthesis process, lost multiple natural components with its association though extracted shikonin Que Lost during purification, and synthetic method can not be synthesized the naphthoquinone derivatives and the Radix Arnebiae (Radix Lithospermi) association composition of multiple natural ratio simultaneously, so medicinal component is single, and curative effect is reduced.
In order to overcome above-mentioned defective, the purpose of this invention is to provide a kind of Radix Arnebiae (Radix Lithospermi) agent and make its medicinal component abundant, the curative effect wide spectrum is convenient to orally, and its preparation technology is simple.
The present invention extracts the agent of Chinese medicine Radix Arnebiae (Radix Lithospermi) like this, through select medicine with the earth in the Radix Arnebiae (Radix Lithospermi), foreign material, damage by worms and the part of going mouldy is chosen, be cut into segment.With the edible wine that contains ethanol 25-65%, soaked at normal temperatures 72-96 hour, when treating ph=7-8, more after filtration, make mauve medicated wine Radix Arnebiae (Radix Lithospermi) oral liquid.
Effect of the present invention is very obvious.1. technology is very simple and direct; 2. Radix Arnebiae (Radix Lithospermi) agent free from admixture, avirulence, the free from extraneous odour of Ti Quing can directly be oral liquid; 3. adopting refined edible wine is solvent, is extractant when pharmacy not only, and is the synergist of controlling benefit during medication, when depositing medicine or antiseptic; 4. the Radix Arnebiae (Radix Lithospermi) agent of the present invention's extraction, remove and contain natural Radix Arnebiae (Radix Lithospermi) naphthoquinone and derivant thereof, the aminoacid, polysaccharide, vitamin and the trace element that increase when extracting that also has the Radix Arnebiae (Radix Lithospermi) association supported etc., this natural Radix Arnebiae (Radix Lithospermi) agent of merging, enriched the medicinal component of Radix Arnebiae (Radix Lithospermi) agent widely, strengthen medicine Synergistic treatment mechanism, met the theory of the extra conductant ingredient in the Chinese medicine and pharmacy.5. prove that former medicine effect has been expanded in Radix Arnebiae (Radix Lithospermi) agent provided by the invention through medical practice, find that the agent of this Radix Arnebiae (Radix Lithospermi) has tangible kidney invigorating and YANG supporting, the spermatogenesis hair growth promoting, blood lipid-reducing blood sugar-decreasing is kept fit the anti-new effect of waiting for a long time.
Accompanying drawing is for extracting the process flow diagram of Chinese medicine Radix Arnebiae (Radix Lithospermi) agent.
Illustrate below in conjunction with accompanying drawing:
Embodiment one
Radix Arnebiae (Radix Lithospermi) is cut into the 3-4cm segment through selecting medicine.Get Radix Arnebiae (Radix Lithospermi) section 1000g, soak with 50% alcoholic acid edible wine 12000ml, soaked at normal temperatures 72 hours, immersion is aubergine, when treating ph=7-8, pours out immersion, leaves standstill 48 hours, crosses leaching liquid, gets the medicated wine Radix Arnebiae (Radix Lithospermi) oral liquid of free from extraneous odour.
Claims (1)
1. the preparation method of broad-spectrum medical functions Radix Arnebiae (Radix Lithospermi) agent is characterized in that: get 1 part of Radix Arnebiae (Radix Lithospermi) root segment, with 12 parts of the edible wine that contains ethanol 25-65%, soaked 72-96 hour down in room temperature, when treating PH=7-8, after filtration, can make processed with wine Radix Arnebiae (Radix Lithospermi) oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011041587A CN1178678C (en) | 2001-02-22 | 2001-02-22 | Process for preparing arnebia root medicine with broad-spectrum medical functions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011041587A CN1178678C (en) | 2001-02-22 | 2001-02-22 | Process for preparing arnebia root medicine with broad-spectrum medical functions |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95110164A Division CN1079239C (en) | 1995-04-12 | 1995-04-12 | Gromwell preparation with wide medical effect and its preparation process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1329904A CN1329904A (en) | 2002-01-09 |
| CN1178678C true CN1178678C (en) | 2004-12-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB011041587A Expired - Fee Related CN1178678C (en) | 2001-02-22 | 2001-02-22 | Process for preparing arnebia root medicine with broad-spectrum medical functions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1178678C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4372017B2 (en) * | 2003-02-21 | 2009-11-25 | 北京金本草中▲やお▼科技▲ふぁ▼展有限公司 | Drugs containing Shikonin compounds as active ingredients |
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2001
- 2001-02-22 CN CNB011041587A patent/CN1178678C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1329904A (en) | 2002-01-09 |
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Addressee: Song Anlin Document name: Notification of Termination of Patent Right |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20041208 |