CN117679147A - Method and system for automatically adjusting power - Google Patents

Method and system for automatically adjusting power Download PDF

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CN117679147A
CN117679147A CN202211074001.1A CN202211074001A CN117679147A CN 117679147 A CN117679147 A CN 117679147A CN 202211074001 A CN202211074001 A CN 202211074001A CN 117679147 A CN117679147 A CN 117679147A
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power
electrode
real
time
ablation
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崔长杰
高永相
刘志宇
徐宏
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Hangzhou Kunbo Biotechnology Co Ltd
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Hangzhou Kunbo Biotechnology Co Ltd
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Priority to CN202211074001.1A priority Critical patent/CN117679147A/en
Priority to TW112100739A priority patent/TWI843390B/en
Priority to PCT/CN2023/115536 priority patent/WO2024046321A1/en
Publication of CN117679147A publication Critical patent/CN117679147A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor

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Abstract

The invention provides a method and a system for automatically adjusting power, which are used for adjusting the output power of an ablation plate, wherein the ablation plate comprises a plurality of electrodes; the method comprises the following steps: acquiring a real-time current value and a real-time voltage value of each electrode of an ablation plate in an ablation process; determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value, and determining a designated electrode from the electrodes based on the real-time impedance; determining a target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power set; based on the real-time power of the at least one electrode and the target monopolar power, the input voltage of the ablation plate is adjusted to adjust the output power of the ablation plate.

Description

Method and system for automatically adjusting power
Technical Field
The invention belongs to the technical field of radio frequency ablation, and particularly relates to a method and a system for automatically adjusting power.
Background
Radio frequency ablation is a treatment method in which high-frequency alternating current is applied to an affected part of a target object until a set energy is reached, for killing specific tissues such as tumor or cancer cells. The method is generally applied to the treatment of common diseases of respiratory system, and is used for solving the problems of incomplete treatment and low efficiency of the traditional drug treatment.
Currently, in the method of radio frequency ablation, the electrodes are usually connected in parallel, and a constant voltage is output until a set ablation energy is reached. However, during ablation, the temperature of the electronic components, including the electrodes, typically increases, thereby increasing the impedance of the electronic components. And an increase in impedance may result in a decrease in the output power of the electrode, thereby affecting ablation efficiency.
Disclosure of Invention
The invention provides a method and a system for automatically adjusting power, which are used for solving the problem that the ablation efficiency is reduced because the relation between temperature and impedance is not considered in the prior art.
The basic scheme of the invention is as follows: a method of regulating power for regulating the output power of an ablation plate, the ablation plate comprising a plurality of electrodes; the method comprises the following steps:
Acquiring a real-time current value and a real-time voltage value of each electrode of an ablation plate in an ablation process;
determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value, and determining a designated electrode from the electrodes based on the real-time impedance;
determining a target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power set;
based on the real-time power of the at least one electrode and the target monopolar power, an input voltage of the ablation plate is adjusted to adjust an output power of the ablation plate.
In the scheme of the invention, the electrodes of the ablation plate are connected in parallel and the real-time power is blocked and influenced, so that a designated electrode can be set according to the real-time impedance of each electrode. Based on the specified electrode, the target unipolar power to which at least one electrode is to be adjusted may be determined from the preset unipolar power, i.e., the real-time power of the at least one electrode may be adjusted as close as possible to the target unipolar power by adjusting the input voltage, whereby the output power may be more accurately adjusted.
Further, determining a designated electrode from the electrodes based on the real-time impedance, comprising: and determining the electrode with the minimum real-time impedance as a designated electrode.
Further, determining a target monopolar power for at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set, comprising: and determining the target monopolar power of the designated electrode based on the set preset monopolar power.
Further, determining the target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set, further comprising:
for each other electrode except the designated electrode, calculating a ratio of the real-time impedance of the designated electrode to the real-time impedance of the other electrode, and determining a target monopolar power of the other electrode based on the ratio of the real-time impedances and the target monopolar power of the designated electrode.
Further, the determining the target monopolar power of the designated electrode based on the set preset monopolar power comprises:
acquiring real-time temperature of an ablation object corresponding to the designated electrode in the ablation process;
determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object corresponding to the designated electrode and a preset temperature threshold; the power adjustment value is used for adjusting the real-time temperature of the ablation object corresponding to the designated electrode;
And determining the target monopolar power of the designated electrode based on the preset monopolar power and the power adjustment value.
Further, the temperature threshold includes a preset temperature range and a preset protection temperature, and the maximum value of the preset temperature range is smaller than or equal to the preset protection temperature; the target monopole power is the sum of the preset monopole power and the power adjustment value;
determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object corresponding to the designated electrode and a preset temperature threshold value, wherein the power adjustment value comprises the following steps:
when the real-time temperature of the specified electrode corresponding to the ablation object is in a preset temperature range, setting a power adjustment value of the specified electrode to 0 so that the target monopolar power is equal to the preset monopolar power;
when the real-time temperature of the specified electrode corresponding to the ablation object is greater than a preset protection temperature, setting a power adjustment value of the specified electrode to be less than 0 so that the target monopolar power is less than the preset monopolar power;
and when the real-time temperature of the specified electrode corresponding to the ablation object is smaller than the minimum value of a preset temperature range, setting the power adjustment value of the specified electrode to be larger than 0 so that the target monopolar power is larger than the preset monopolar power.
Further, adjusting an input voltage of the ablation plate based on the real-time power of the at least one electrode and the target monopolar power, comprising:
determining the sum of target monopolar powers of all the electrodes in the at least one electrode as target total power;
the input voltage to the ablation plate is adjusted based on a difference between a sum of real-time power of all of the at least one electrode and the target total power.
Further, adjusting an input voltage to the ablation plate based on a current difference between a sum of real-time power of all of the at least one electrode and the target total power, comprising:
determining a sum of historical real-time powers based on the last acquired real-time powers of all the at least one electrode, and determining a historical difference between the sum of historical real-time powers and the target total power;
searching a current power difference value range and a corresponding voltage variation, to which the current difference value belongs, and a historical power difference value range to which the historical difference value belongs in a corresponding relation table of a preset power difference value range and a voltage variation;
if the current difference range is different from the historical power difference range, adjusting the input voltage of the ablation plate according to the corresponding voltage variation;
And if the current difference range is the same as the historical power difference range, acquiring the currently set voltage variation, reducing the currently set voltage variation, and adjusting the input voltage of the ablation plate according to the reduced voltage variation.
Further, the method further comprises:
according to the real-time current value and the real-time voltage value of each path of electrode, calculating to obtain real-time energy generated by each path in unit time;
accumulating the real-time energy generated by each path in each unit time to obtain the total energy generated by the path electrode;
and if the total energy is equal to a preset energy value, adjusting the output power of a circuit where the circuit electrode is positioned to be 0.
The invention also provides an ablation system, which comprises a power output plate and an ablation plate; the ablation plate comprises a central processing unit, a sampling unit and a plurality of electrodes, wherein,
the electrode is connected with one or more ablation objects and is used for ablating the connected ablation objects;
the sampling unit is used for detecting the real-time current value and the real-time voltage value of each electrode and sending the real-time current value and the real-time voltage value to the central processing unit;
the central processing unit is used for: determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value sent by the sampling unit, and determining a designated electrode from the electrodes based on the real-time impedance; and determining a target electrode monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set; and determining a control voltage signal to be transmitted by the ablation plate based on the real-time power of the at least one electrode and the target monopolar power, and transmitting the control voltage signal to a power output plate;
The power output plate is used for determining target voltage according to the control voltage signal sent by the central processing unit and adjusting the output power of the electrode according to the control voltage signal.
Further, the sampling unit is further configured to detect a real-time temperature of the ablation object connected to the specified electrode, and send the real-time temperature to the central processing unit;
the central processing unit is further configured to: determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object connected with the designated electrode and a preset temperature threshold; and determining a target monopolar power of the designated electrode based on the preset monopolar power and the power adjustment value that have been set; wherein the power adjustment value is used to adjust the real-time temperature of an ablation object connected to the designated electrode.
Further, the ablation plate further comprises a relay control unit; the relay control unit is connected with the plurality of electrodes and is used for controlling the on-off of each electrode;
the central processing unit is further configured to: according to the real-time current value and the real-time voltage value of each electrode, calculating to obtain real-time energy generated by each path in unit time; the real-time energy generated by each path in each unit time is accumulated to obtain the total energy generated by the path electrode; and if the total energy is equal to a preset energy value, controlling the relay unit to disconnect the circuit electrode so as to adjust the output power of the circuit where the circuit electrode is positioned to be 0.
Drawings
Fig. 1 is a schematic flow chart of a method for automatically adjusting power according to a first embodiment of the present invention;
FIG. 2 is a schematic block diagram of a system for automatically adjusting power according to a second embodiment and a third embodiment of the present invention;
FIG. 3 is a schematic block diagram illustrating an example of a system for automatically adjusting power according to a third embodiment of the present invention;
FIG. 4 is a block diagram of the sampling unit of FIGS. 2 and 3;
FIG. 5 is a schematic diagram of the current detection circuit in FIG. 4;
FIG. 6 is a schematic circuit diagram of the current detection circuit of FIG. 4;
FIG. 7 is a schematic diagram of the voltage detection circuit in FIG. 4;
FIG. 8 is a schematic circuit diagram of the voltage detection circuit in FIG. 4;
FIG. 9 is a schematic block diagram of the neutral electrode detection circuit of FIG. 4;
FIG. 10 is a schematic circuit diagram of the neutral electrode detection circuit of FIG. 4;
FIG. 11 is a schematic diagram of a module of the temperature detection circuit in FIG. 4;
FIG. 12 is a schematic circuit diagram of the temperature sensing circuit of FIG. 4;
FIG. 13 is a block diagram of the relay control circuit of FIG. 4;
FIG. 14 is a circuit schematic of the bitmap 13 relay unit;
fig. 15 is a circuit schematic of the power output board of fig. 2.
Detailed Description
The following is a further detailed description of the embodiments:
for the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the following detailed description of the embodiments of the present invention will be given with reference to the accompanying drawings. However, those of ordinary skill in the art will understand that in various embodiments of the present invention, numerous technical details have been set forth in order to provide a better understanding of the present application. However, the technical solutions claimed in the present application can be implemented without these technical details and with various changes and modifications based on the following embodiments.
Embodiment one:
a first embodiment of the present invention provides a method of automatically adjusting power for adjusting the output power of an ablation plate comprising a plurality of electrodes; the method comprises the following steps: acquiring a real-time current value and a real-time voltage value of each electrode of an ablation plate in an ablation process; determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value, and determining a designated electrode from the electrodes based on the real-time impedance; determining a target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power set; based on the real-time power of the at least one electrode and the target monopolar power, an input voltage of the ablation plate is adjusted to adjust an output power of the ablation plate.
When the method is implemented, the ablation plate acquires an ablation starting signal; according to the ablation starting signal, starting ablation; acquiring a real-time current value and a real-time voltage value of each electrode in real time in an ablation process; determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value; determining a designated electrode from the electrodes according to the real-time impedance of each electrode; determining a target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power set; and adjusting the input voltage of the ablation plate according to the real-time power of the at least one electrode and the target monopolar power so as to adjust the output power of the ablation plate.
In this embodiment, the electrodes of the ablation plate are connected in parallel and the real-time power is blocked from being affected, so that a given electrode can be set according to the real-time impedance of each electrode. Based on the specified electrode, the target unipolar power to which at least one electrode is to be adjusted may be determined from the preset unipolar power, i.e., the real-time power of the at least one electrode may be adjusted as close as possible to the target unipolar power by adjusting the input voltage, whereby the output power may be more accurately adjusted.
The implementation details of a method for automatically adjusting power according to this embodiment are specifically described below, and the following description is provided only for understanding the implementation details, but is not required to implement this embodiment, and a specific flow of this embodiment is shown in fig. 1, where this embodiment is applied to a system for automatically adjusting power.
Step 101, acquiring real-time current values and real-time voltage values of electrodes of an ablation plate in an ablation process.
Specifically, the implementation precondition of the present step 101 is two, one of which is that the ablation plate directly performs step 101 after being directly electrified, and the other two ablation plates perform step 101 after acquiring an ablation start signal.
In some examples, prior to step 101, the method further comprises: s100, acquiring an ablation starting signal.
Specifically, the ablation initiation signal is sent under the control of the user himself. Typically, the user triggers by clicking, selecting, etc. through the dashboard to generate the ablation initiation signal. In practice, the ablation initiation signal is typically received by a communication unit of the ablation plate, and is typically transmitted in the form of two signals, low_mcu_rx and low_mcu_tx.
In some examples, step 101 includes: s1-1, acquiring real-time current values of all electrodes in an ablation process; s1-2, acquiring real-time voltage values of all electrodes in the ablation process.
Specifically, S1-1 obtains real-time current values of each electrode in an ablation process, including: s1-1-1, differentially amplifying a current signal to be detected to obtain an amplified current signal; s1-1-2, carrying out half-wave rectification on the amplified current signal, rectifying the amplified current signal into a waveform of a positive half shaft, and obtaining a current rectification waveform; s1-1-3, performing direct current filtering on the current rectification waveform to obtain an approximate direct current signal; s1-1-4, converting the approximate direct current signal into a signal with a waveform close to linearity, and performing RC filtering to obtain a stable current; s1-1-5, detecting the current value of the stable current, and calculating the current value of the current signal to be detected according to a preset coefficient. Wherein the preset coefficient is associated with the multiple of differential amplification, the coefficient of half-wave rectification, the DC filter coefficient and the RC filter coefficient.
And amplifying the current signal to be detected in a differential amplification mode, and improving the detection accuracy of the current signal to be detected under the condition that the detection accuracy is unchanged. The output current is more stable and basically does not fluctuate through RC filtering, and the quasi-deterministic decline of the detection result due to fluctuation is avoided.
Specifically, S1-2, the real-time voltage value of each electrode in the ablation process is obtained, which comprises the following steps: s1-2-1, attenuating the voltage signal to be detected to obtain an attenuated voltage signal; s1-2-2, carrying out half-wave rectification on the attenuated voltage signal, rectifying the attenuated voltage signal into a waveform of a positive half shaft, and obtaining a voltage rectification waveform; s1-2-3, performing direct current filtering on the voltage rectification waveform to obtain an approximate direct current voltage signal; s1-2-4, converting the approximate direct-current voltage signal into a signal with a waveform close to linearity, and performing RC filtering to obtain a stable voltage; s1-2-5, detecting the current value of the stable voltage, and calculating the current voltage value of the voltage signal to be detected according to a preset coefficient. Wherein the preset coefficient is associated with a multiple of the attenuation, a half-wave rectification coefficient, a direct current filter coefficient and an RC filter coefficient.
The measured voltage value is attenuated by the resistor voltage dividing circuit, and the voltage signal is attenuated to a state convenient to measure in a resistor voltage dividing mode because the measured voltage value is overlarge. The waveform is modulated and filtered, so that the voltage for detection is more stable and basically does not fluctuate, and the detection result is prevented from quasi-deterministic decline due to fluctuation.
And 102, determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value, and determining a designated electrode from the electrodes based on the real-time impedance.
Specifically, the real-time impedance R of the same electrode is calculated from the real-time current value I and the real-time voltage value U of the same electrode by combining the formula r=u/I. One of the electrodes is then selected as the designated electrode based on the corresponding real-time impedance of the electrodes.
In one embodiment, determining a designated electrode from the electrodes based on the real-time impedance includes: determining the electrode with the smallest real-time impedance as a designated electrode, e.g. the designated electrodeThe impedance of the pole is denoted as R min 。
In one embodiment, the real-time impedance for each electrode may reflect whether the electrode is in contact with the target object, and for electrodes that are not in contact with the target object, an invalid electrode may be determined, which is removed when the designated electrode is determined. For example, in step S102, before determining a specific electrode from the electrodes based on the real-time impedance, the method further performs screening on the electrodes involved in calculating the monopolar ablation power, where the screening process is as follows: s2-1, acquiring a preset maximum impedance value and a preset minimum impedance value; and S2-2, when the current impedance corresponding to the electrode is larger than the maximum impedance value or smaller than the minimum impedance value, the electrode is not counted into the calculation range of the monopole ablation power.
Judging whether the electrode is abutted or not through the minimum impedance value and the maximum impedance value set by a user; specifically, if the current impedance is greater than the minimum impedance value and less than the maximum impedance value, determining that the electrode corresponding to the current impedance is well attached; and if the current impedance corresponding to the electrode is larger than the maximum impedance value or smaller than the minimum impedance value, judging that the current impedance corresponding to the electrode is poor in contact.
And step 103, determining the target monopolar power of at least one electrode in the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power which is set.
The preset monopolar power may be determined empirically by the user, for example, as the maximum power achievable by a single electrode.
The target unipolar power may be understood as the target power to be adjusted. For example, for a specific electrode, the current real-time power of the specific electrode is 1W, and if the target monopolar power of the specific electrode is determined to be 2W, 2W may be used as the target power to be adjusted to the specific electrode, i.e. the real-time power of the specific electrode is adjusted to be as close to 2W as possible.
In one embodiment, at least one electrode may include only a designated electrode. Based on this, the implementation of step 103 may include:
S3-1, determining the target monopolar power of the designated electrode based on the preset monopolar power.
In one embodiment, the at least one electrode may include a designated electrode and other electrodes, for example, may include all electrodes in the ablation plate, or may include all electrodes in the ablation plate except for the non-abutted electrode. Based on this, the implementation of step 103 may further include, in addition to S3-1 described above:
s3-2, calculating the real-time impedance R of the designated electrode for each other electrode except the designated electrode min Ratio R of real-time impedance to the other electrode (e.g. denoted R) min And determining the target monopolar power of the other electrode based on the ratio of the real-time impedance and the target monopolar power of the designated electrode.
The above steps S3-1 and S3-2 are specifically described below.
In the implementation, in S3-1, a preset unipolar power P' is first set, and a target unipolar power P for the specified electrode is set based on the preset unipolar power P 0 . For example, the preset unipolar power P' may be set to the target unipolar power P of the specified electrode 0 The method comprises the steps of carrying out a first treatment on the surface of the Alternatively, a power adjustment value may be determined in combination with the temperature adjustment mechanism to determine the target monopolar power P based on the preset monopolar power P' and the power adjustment to ΔP 0 . It can be understood that, since the resistance of the designated electrode is the smallest among all the electrodes, the power of the designated electrode is the largest among all the electrodes, so that if the designated electrode is adjusted to the preset monopolar power, the whole circuit can reach the maximum power on the whole on the basis that the power of all the electrodes does not exceed the preset monopolar power, and the ablation efficiency is improved.
In one embodiment, the target monopolar power P of the designated electrode may also be determined based on a preset monopolar power P' and a temperature adjustment mechanism 0 And is described in detail below, and is not described in detail herein.
Alternatively, the preset monopole power value P' may be preset by the following several ways: (1) The monopolar power value P' set by the user is determined according to experience of an operator, and the operator decides different ablation powers according to different ablation positions and ablation depths. (2) The historical ablation part, ablation depth and monopole power value are assembled into a set to be made into a table; and searching through a table according to the detected ablation part and the detected ablation depth to obtain the corresponding ablation depth. (3) Forming a basic data set by using the historical ablation parts, the ablation depths and the monopole power values, and training the basic data set by using a neural network model to obtain a plurality of models which are associated with the historical ablation parts, the corresponding ablation depths and the monopole power values; substituting the detected ablation positions and the corresponding ablation depths of the ablation positions into a trained neural network model to obtain corresponding preset unipolar power values P'. It should be noted that the above-mentioned modes are merely exemplary, and in practical application, the present embodiment may be determined by other methods, which is not limited.
In some examples, step S3-1 may further include: s3-1-1, acquiring real-time temperature of an ablation object corresponding to the designated electrode in the ablation process; s3-1-2, determining a power adjustment value delta P of the designated electrode according to a comparison result between the real-time temperature of the ablation object corresponding to the designated electrode and a preset temperature threshold, wherein the power adjustment value delta P is used for adjusting the real-time temperature of the ablation object corresponding to the designated electrode; s3-1-3, determining the target monopolar power P of the designated electrode based on the preset monopolar power P' and the power adjustment value DeltaP 0 。
It will be appreciated that when the ablation plate ablates the ablation object through the electrode, the temperature of the ablation object is actually controlled to ablate. Therefore, effective ablation must control the temperature of the ablation subject within a suitable range.
In one embodiment, in S3-1-2, the temperature threshold may include a preset temperature range [ a, b ] and a preset protection temperature c, where a maximum value b of the preset temperature range is less than or equal to the preset protection temperature c, i.e., b.ltoreq.c. The preset temperature range may be understood as a suitable range with a good ablation effect, and the preset protection temperature may be understood as a highest temperature for preventing the ablation object from being damaged. For ease of description, the real-time temperature of the ablation object to which a given electrode corresponds is denoted herein as x.
Specifically, S3-1-2, determining, according to a comparison result between the real-time temperature of the ablation object corresponding to the specified electrode and a preset temperature threshold, a power adjustment value of the specified electrode includes:
s3-1-2-1, wherein the real-time temperature x of the specified electrode corresponding to the ablation object is in a preset temperature range [ a, b ]]Time (i.e. x E [ a, b)]) Setting the power adjustment value delta P of the designated electrode to 0 to maintain the current output power P of the designated electrode 0 ；
S3-1-2-2, when the real-time temperature x of the specified electrode corresponding to the ablation object is greater than the preset protection temperature c (i.e. x > c), setting the power adjustment value delta P of the specified electrode to be less than 0 so as to reduce the current output power P of the specified electrode 0 ；
It will be appreciated that if the real-time temperature of the ablated object is greater than the preset protection temperature, damage to the ablated object may occur, and therefore immediate temperature reduction is required. In one example, the temperature may be reduced by reducing the power.
S3-1-2-3, when the real-time temperature x of the specified electrode corresponding to the ablation object is smaller than the minimum value a of the preset temperature range [ a, b ] (namely x is smaller than a), setting the power regulating value delta P of the specified electrode to be larger than 0 so as to improve the current output power of the specified electrode.
It is understood that if the real-time temperature of the ablation object is less than the minimum value of the preset temperature range, the ablation effect may be poor due to the excessively low temperature. Therefore, the power is improved, so that the ablation effect can be improved, and the ablation efficiency can be improved.
In some examples, the ablation plate further comprises an infusion pump for focusing physiological saline on the corresponding ablation subject of the designated electrode to reduce the current temperature of the corresponding ablation subject. Thus, the current temperature of the ablation subject may be reduced by increasing the infusion pump flow rate; the current temperature of the ablation subject may be raised by decreasing the infusion pump flow rate. Specifically, (1) inWhen the real-time temperature x of the specified electrode corresponding to the ablation object is larger than the preset heat preservation temperature, namely x is larger than c, the flow velocity v of the physiological saline injected by the perfusion pump can be increased first, if the real-time temperature x is still larger than c under the condition that the perfusion pump flow is lifted to the highest, the power adjusting value delta P of the specified electrode is smaller than 0, so that the target monopolar power is reduced on the basis of the preset monopolar power, and the real-time temperature of the ablation object is lower than the protection temperature; alternatively, the power adjustment value may be determined according to the current real-time power and the target monopolar power, for example, such that the power adjustment value is smaller than a difference between the real-time power and the preset monopolar power, such that the target monopolar power is smaller than the real-time power, thereby rapidly decreasing the temperature of the target object by decreasing the power; (2) When the real-time temperature x of the specified electrode corresponding to the ablation object is greater than the maximum value b of the preset temperature range and less than or equal to the preset protection temperature c, namely x epsilon (b, c) ]Increasing the flow velocity v of the normal saline injected by the perfusion pump until the flow velocity v is greater than the maximum flow velocity v max The method comprises the steps of carrying out a first treatment on the surface of the Optionally, in the case that the perfusion pump flow is lifted to the highest, the power adjustment value Δp of the designated electrode may be set to be less than 0, so that the target monopolar power is reduced on the basis of the preset monopolar power, so that the real-time temperature of the ablation object is in a suitable range; (3) The real-time temperature x of the specified electrode corresponding to the ablation object is in a preset temperature range [ a, b ]]When x is E [ a, b]The power adjustment value delta P of the designated electrode is set to 0, so that the preset unipolar power can be directly used as the target power P 0 The method comprises the steps of carrying out a first treatment on the surface of the (4) When the real-time temperature x of the specified electrode corresponding to the ablation object is smaller than the minimum value a of the preset temperature range, namely x is smaller than a, the power adjustment value delta P of the specified electrode is larger than 0, so that the target monopolar power is improved on the basis of the preset monopolar power, the real-time temperature of the ablation object can be improved, the ablation effect can be improved, the ablation efficiency can be improved, and the ablation time can be shortened; optionally, if the real-time temperature x of the ablation object is still smaller than the minimum value a after the monopole maximum power is reached, the flow velocity v of the physiological saline injected by the perfusion pump can be adjusted downwards until the flow velocity v is adjusted downwards to the minimum value v min 。
In one embodiment, the power adjustment value Δp may be a preset fixed value, for example Δp= -1 when Δp < 0 is determined; when Δp >0 is determined, Δp=1, and the like. Or, the power adjustment value Δp is determined according to a preset correspondence between the temperature difference and the power adjustment value, for example: when x is e (b, c), the power adjustment value may be determined according to the difference between x and b, and in general, the difference is positively correlated with the absolute value of the power adjustment value.
Specifically, S3-1-3, determining the target monopolar power P of the designated electrode based on the preset monopolar power P' and the power adjustment value ΔP 0 Comprising the following steps: adding the preset monopole power value P' set by a user and the adjustment quantity delta P generated by a temperature adjustment mechanism to obtain monopole ablation power P 0 The method comprises the steps of carrying out a first treatment on the surface of the The preset monopolar power P' is preset by a user according to an ablation position and an ablation depth, the ablation temperature can be changed in real time in the ablation process, and the temperature regulation mechanism can control the ablation temperature to be in a proper range.
In S3-2, the ratio k of the real-time impedance of the specified electrode to the real-time impedance of the other electrode=real-time impedance Rmin of the specified electrode/real-time impedance R of the other electrode. The target monopolar power of the other electrode is determined based on the ratio of the real-time impedances and the target monopolar power of the designated electrode. For example, the ratio of the target monopolar power to the ratio of the real-time impedance may be inversely proportional between the other electrodes and the designated electrode. The method comprises the following steps: according to inverse proportion relation Calculating target monopolar power P required to be output of each electrode x The method comprises the steps of carrying out a first treatment on the surface of the Wherein R is x Representing the impedance value of the current electrode (i.e. any other electrode than the specified electrode), R min Representing the impedance value of the designated electrode, P 0 Representing the target monopolar power of the designated electrode, P x Representing the current electrode (i.e. the impedance value is R x Is provided) the target monopolar power. If in the electrode in normal working stateN electrodes in addition to the designated electrode, the target monopolar power per electrode can be noted as P 1 ～P n Wherein x is in the range of [1, n ]]The value of n is a positive integer.
In this step, the electrodes are connected in parallel and the real-time power is affected by the impedance R, and the smaller the impedance R, the larger the real-time power P of the electrodes. It can be seen that the electrode with the smallest impedance R in each path has the real-time power P that is the largest power value in each path. Therefore, the electrode with the smallest impedance is set as the designated electrode, and the target unipolar power to which the designated electrode is to be adjusted can be determined according to the preset unipolar power, i.e. the real-time power of the designated electrode is adjusted to be as close to the preset unipolar power as possible. Meanwhile, the target monopolar power of other electrodes is determined according to the target monopolar power of the designated electrode, and the target monopolar power of other electrodes can be also determined when the power is adjusted subsequently: the real-time power of each electrode is adjusted to be as large as possible so as to realize the maximum output power value of the whole circuit and improve the ablation efficiency. In addition, the calculation of the monopolar ablation power takes into account the real-time change of the temperature of each electrode along with the ablation degree, and a temperature adjustment mechanism is set based on the change of the temperature, so that the monopolar ablation power fully considers the temperature factor. In the temperature regulation mechanism, the set monopole ablation power is taken as a reference, and the temperature in the ablation process can be always below the protection temperature.
Step 104, adjusting an input voltage of the ablation plate based on the real-time power of the at least one electrode and the target monopolar power to adjust an output power of the ablation plate.
Specifically, the implementation of step 104 includes: s4-1, determining the sum of target monopolar powers of all the electrodes in the at least one electrode as target total power; s4-2, adjusting the input voltage of the ablation plate based on the difference between the sum of the real-time power of all the at least one electrode and the target total power.
Wherein at least one electrode may include only a designated electrode; or may include both the designated electrode and other electrodes.
In one embodiment, where at least one electrode includes only the designated electrode, the real-time power, i.e., the "sum of real-time powers" described in step 104, may be calculated from the real-time voltage and current values of the designated electrode; the target monopolar power for the designated electrode may then be taken as the "target total power" in step 104, such that the input voltage may be adjusted based on the real-time power for the designated electrode and the target monopolar power.
It can be understood that in this embodiment, the input voltage is fed back by the power of a single electrode (i.e. the designated electrode), so that the calculation is simple and quick, and the calculation efficiency is improved on the basis of ensuring the accuracy.
In one embodiment, at least one electrode comprises a designated electrode and other electrodes, and the real-time power of each electrode can be calculated according to the real-time voltage value and the current value of each electrode, and then the sum of the real-time powers is determined by adding; the target monopolar power corresponding to each electrode can then be added to obtain the target total power "Thus, the input voltage can be adjusted based on the sum of the real-time powers and the target total power.
The other electrodes can include electrodes which are effectively abutted, and whether the electrodes are effectively abutted or not can be judged through the impedance of the electrodes. An electrode having a current impedance less than or equal to a maximum impedance value and greater than or equal to the minimum impedance value; the maximum impedance value and the minimum impedance value are set by a user; electrodes in the range of 'the current impedance is smaller than or equal to the maximum impedance value and is larger than or equal to the minimum impedance value' are regarded as being well-attached, and the power calculation range is counted; the electrodes in the other cases were not or poorly attached, and the power calculation range was not considered.
It can be appreciated that the present embodiment feedback-controls the output voltage by the total power of the entire circuit with higher reliability than the direct control by the unipolar output power and the unipolar target power; meanwhile, as the resistance of each electrode in the circuit is changed in real time, the designated electrode with the smallest resistance is also changed (for example, the original designated electrode is electrode 1 and changed into electrode 2), so that the fluctuation of instantaneous voltage can be reduced by feeding back the total power of the whole circuit, and stable output is facilitated.
Specifically, S4-2, adjusting the input voltage of the ablation plate based on the current difference between the sum of the real-time power of all of the at least one electrode and the target total power, comprising:
s4-2-1, determining a sum of historical real-time powers based on the last acquired real-time powers of all the at least one electrode, and determining a historical difference between the sum of the historical real-time powers and the target total power; searching a current power difference range and a corresponding voltage variation to which the current difference delta P belongs and a historical power difference range to which the historical difference belongs in a corresponding relation table of a preset power difference range and a voltage variation (DAC voltage variation); wherein the correspondence table includes an associated power difference range and voltage variation (DAC voltage variation).
In S4-2, the preset correspondence table between the power difference range and the voltage variation is a relationship between the power difference range, the power variation range and the DAC variation after multiple experiments, and a correlation between multiple sets of data is summarized. The comparison table can be a plurality of maps which are in one-to-one correspondence, can also be a database formed by sorting historical data, and can also be a model between the summarized power difference range and DAC variation.
In one embodiment, after sampling the current value and the voltage value each time, the real-time power of all the electrodes in the at least one electrode can be calculated, and then the difference between the real-time power and the target total power is calculated and recorded, for example, in a history difference table; or only the last calculated difference may be recorded; or only record the difference range corresponding to the difference of last time or history multiple times, for example record the serial number corresponding to the difference range.
Optionally, when recording the historical difference or the historical difference range, the difference range may be initialized before the first recording, and the value of the difference range to be calculated and judged by the software is first assigned to the original unadjusted state, so as to prevent the operation from being affected by the previously tested data.
In one embodiment, for the real-time power obtained by the first sampling, the voltage variation corresponding to the difference may be directly found in a preset correspondence table between the power difference range and the voltage variation, and then directly adjusted according to the voltage variation.
In one embodiment, for the real-time power obtained by non-first sampling, after the current difference value is obtained by calculation, the historical difference value calculated last time can be searched; and then searching a current power difference value range to which the current difference value belongs and a historical power difference value range to which the historical difference value belongs in a corresponding relation table respectively, and comparing.
And S4-2-2, if the current power difference range is different from the historical power difference range, adjusting the input voltage of the ablation plate according to the corresponding voltage variation, namely updating the set DAC variation from the last DAC variation to the current DAC variation corresponding to the power variation range obtained in the S4-2-1.
Wherein the set DAC variation can be used to adjust the input voltage and thus the output power.
S4-2-3, if the current power difference range is the same as the historical power difference range, acquiring the current set voltage variation, reducing the current set voltage variation, and adjusting the input voltage of the ablation plate according to the reduced voltage variation, so that the output power can be adjusted.
Further, in S4-2-3, the current set voltage variation is obtained, and the current set voltage variation is reduced, including: the voltage variation (DAC variation) is reduced according to a preset fixed reduction value, i.e. the set DAC variation is updated as: original DAC variation-fixed reduction; wherein the fixed reduction value is a preset value.
When the input voltage is regulated, the current DAC value is fed back to related modules in the power supply circuit according to the DAC value which is added to the current DAC value according to the set DAC variation, and the output voltage is regulated by the related modules, so that the output power value is regulated.
It will be appreciated that in this step, the DAC variation used to adjust the input voltage is not kept constant, but the DAC variation is continuously reduced, and is continuously curved to approach the preset threshold, so that the fluctuation of the output voltage can be reduced, and the influence on the output power can be reduced.
In addition, after the implementation of step 101, the method may further include the following:
step 105, limiting the energy generated by the electrodes in unit time according to the current value and the voltage value of each electrode in real time.
Specifically, the implementation of step 105 includes: s5-1, calculating energy generated by accumulating each path in unit time according to the current value and the voltage value of each path of electrode in real time by combining a serial-parallel connection mode; s5-2, accumulating the real-time energy generated by each path in each unit time to obtain the total energy generated by the path electrode; s5-3, comparing the total energy generated by accumulation of each path with the value of a preset energy value; s5-4, when the total energy generated by accumulation is equal to a preset energy value, the output power is adjusted to be 0.
The preset total energy is preset by a user and can be the ablation energy required for achieving the ablation effect. That is, when the total energy accumulated by the electrode circuit reaches the preset total energy, the ablation object of the electrode can be considered to have reached the ablation effect, and the electrode can stop the ablation.
In one embodiment, when the total energy output by any one electrode reaches a preset energy value, it can be determined that the ablation object of the electrode reaches an ablation effect, so that the electrode can be controlled to be turned off by turning off the relay corresponding to the electrode, and the energy operation is stopped, so that the electrode is prevented from being burnt out, and unnecessary damage to the ablation object is prevented.
The relays are in one-to-one correspondence with the electrodes, and the relays are used for controlling the on-off of the corresponding electrodes. The electrodes are provided with control relays which are in one-to-one correspondence, the control relays are used for controlling the on-off of each electrode, the individual control of the ablation time of each electrode is realized, and the energy output consistency of each electrode is realized by the individual control of the ablation time of each electrode.
And step 106, judging whether all the electrodes in the two paths led out by the negative connecting plate are attached or not according to the current value and the voltage value of each path of electrode in real time.
Specifically, the implementation of step 106 includes: s6-1, comparing the current value of one path of negative plate contact with the current value of the other path of negative plate contact; s6-2, alarming when the current value of one path of negative plate contact is equal to the current value of the other path of negative plate contact.
When the current on one side is twice that on the other side, the situation that the side with the small current value is not attached well can be judged, and an alarm is directly given to prompt a user to adjust the position of the negative plate. For example: when the difference of the two paths of current is 1 time, i.e. I 1 ＝2I 2 When the current is small, the path I is judged 2 In a state of not being well attached, when the situation occurs, the software can send out an alarm signal to prompt the user to manually adjust the position of the negative plate.
And 107, detecting the temperature of each electrode, and turning off the relay corresponding to the electrode when the temperature reaches the upper limit value.
Specifically, the implementation of step 107 includes: s7-1, detecting the current temperature of each electrode when each electrode performs an ablation process; s7-2, comparing the current temperature with a preset upper temperature limit value; and when the current temperature is greater than or equal to the upper temperature limit value, the relay is controlled to be turned off. The relays are in one-to-one correspondence with the electrodes, and the relays are used for controlling the on-off of the corresponding electrodes. The electrodes are provided with control relays which are in one-to-one correspondence, the control relays are used for controlling the on-off of each electrode, the individual control of the ablation time of each electrode is realized, and the energy output consistency of each electrode is realized by the individual control of the ablation time of each electrode. When the temperature of one electrode exceeds the set upper temperature limit value, the corresponding relay is controlled to be turned off, the subsequent ablation operation is not executed, and the occurrence of faults is avoided.
The above steps of the methods are divided, for clarity of description, and may be combined into one step or split into multiple steps when implemented, so long as they include the same logic relationship, and they are all within the protection scope of this patent; it is within the scope of this patent to add insignificant modifications to the algorithm or flow or introduce insignificant designs, but not to alter the core design of its algorithm and flow.
Embodiment two:
a second embodiment of the present invention provides an ablation system, as shown in fig. 2, comprising a power output plate 22 and an ablation plate 23; the ablation plate 23 comprises a central processing unit 232, a sampling unit 233 and a plurality of electrodes, wherein,
the electrode is connected with one or more ablation objects and is used for ablating the connected ablation objects;
the sampling unit 233 is configured to detect a real-time current value and a real-time voltage value of each electrode, and send the real-time current value and the real-time voltage value to the central processing unit;
the central processing unit 232 is configured to: determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value sent by the sampling unit 233, and determining a designated electrode from the electrodes based on the real-time impedance; and determining a target electrode monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set; and determining a control voltage signal to be transmitted by the ablation plate based on the real-time power of the at least one electrode and the target monopolar power, and transmitting the control voltage signal to a power output plate 22;
The power output board 22 is configured to determine a target voltage according to a control voltage signal sent by the central processing unit, and adjust the output power of the electrode according to the control voltage signal.
It will be appreciated that the control voltage signal that the ablation plate needs to send can be understood as a control voltage signal that is indicative of the target voltage.
In the above embodiments, the electrodes of the ablation plate are connected in parallel and the real-time power is blocked from being affected, whereby one designated electrode can be set according to the real-time impedance of each electrode. Based on the specified electrode, the target unipolar power to which at least one electrode is to be adjusted may be determined from the preset unipolar power, i.e. the real-time power of the at least one electrode is adjusted as close as possible to the target unipolar power by adjusting the input voltage, whereby the output power may be adjusted more accurately.
In one embodiment, the sampling unit is further configured to detect a real-time temperature of the ablation object connected to the designated electrode, and send the real-time temperature to the central processing unit.
Based on this, the central processing unit is also for: determining a power adjustment value of a designated electrode according to a comparison result between the real-time temperature of an ablation object connected with the designated electrode and a preset temperature threshold; and determining a target monopolar power of the designated electrode based on the preset monopolar power and the power adjustment value that have been set; wherein the power adjustment value is used to adjust the real-time temperature of an ablation object connected to the designated electrode.
When calculating the monopole ablation power and the maximum output power, the influence of temperature on the overall impedance is fully considered, and the adjustment quantity corresponding to the temperature adjustment mechanism represents the influence quantity (the change quantity of the current value/the voltage value) on the impedance due to temperature change. The adjustment quantity corresponding to the temperature adjustment mechanism is used as one of calculation factors for calculating the monopole ablation power and the maximum output power, so that the monopole ablation power and the maximum output power are calculated more accurately, and the output power is adjusted more accurately.
In one embodiment, the ablation plate further comprises a relay control unit; and the relay control unit is connected with the plurality of electrodes and is used for controlling the on-off of each electrode. For example, the relay control unit may include a plurality of relay control subunits, each subunit being in one-to-one correspondence with each electrode, so that each subunit controls on-off of the corresponding electrode.
In one embodiment, the central processing unit is further configured to: according to the real-time current value and the real-time voltage value of each electrode, calculating to obtain real-time energy generated by each path in unit time; the real-time energy generated by each path in each unit time is accumulated to obtain the total energy generated by the path electrode; and if the total energy is equal to a preset energy value, controlling the relay unit to disconnect the circuit electrode so as to adjust the output power of the circuit where the circuit electrode is positioned to be 0.
Alternatively, the power output plate may be connected to the relay control unit, so that the power output plate may be connected to the electrode through the relay control unit to output power to the electrode. Thus, when the relay control unit is conducted, the power output plate can output power to the electrode; when the relay control unit is turned off, the power output board cannot output power to the electrode, and the output power of the electrode is 0.
It is to be noted that this embodiment is a system example corresponding to the first embodiment, and can be implemented in cooperation with the first embodiment. The related technical details mentioned in the first embodiment are still valid in this embodiment, and in order to reduce repetition, a detailed description is omitted here. Accordingly, the related art details mentioned in the present embodiment can also be applied to the first embodiment.
Embodiment III:
this embodiment is based on the second embodiment and further provides a system for automatically adjusting power, as shown in fig. 2, comprising a power output plate 22 and an ablation plate 23. The central processing unit 232 in the ablation plate 23 initiates an ablation mode into an ablation procedure according to the ablation initiation signal. The ablation initiation signal may include one or more of a preset single level ablation power value, a maximum impedance value, and a minimum impedance value.
The ablation plate 23 comprises a central processing unit 232, a sampling unit 233. The sampling unit 233 is configured to collect real-time current values and real-time voltage values of each electrode in the ablation process, and send the real-time current values and the real-time voltage values to the central processing unit 232.
The central processing unit 232 is further configured to determine a real-time impedance of each electrode according to the real-time current value and the real-time voltage value sent by the sampling unit 233, and determine a designated electrode from the electrodes based on the real-time impedance; and determining a target monopolar power for at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set; and determining a control voltage signal to be transmitted by the ablation plate based on the real-time power of the at least one electrode and the target monopolar power, and transmitting the control voltage signal to a power output plate 22;
the power output board 22 is configured to determine a target voltage according to a control voltage signal sent by the central processing unit 232, and adjust the output power of the electrode according to the control voltage signal.
In some examples, as shown in fig. 3, the system for automatically adjusting power further includes a control board 21, which also includes a communication unit 231. The control board 21 is used for sending an ablation start signal to the communication unit 231 of the ablation board 23; the ablation initiation signal may include one or more of a preset single level ablation power value, a maximum impedance value, and a minimum impedance value. The communication unit 231 of the ablation plate 23 is configured to receive an ablation start signal sent by the control board 21, and send the ablation start signal to the central processing unit 232, so that the central processing unit 232 starts an ablation mode according to the ablation start signal, and enters an ablation process.
Remote control of the ablation plate 23 is achieved by the control plate 21, directly or indirectly inputting an ablation start signal. The ablation initiation signal received by the central processing unit 232 may be derived from the input of the control board 21, may be generated by itself, or may be generated after receiving a user command by other means, etc., which is not limited in this embodiment.
In one embodiment, the ablation plate further comprises a relay control unit connected with the plurality of electrodes and used for controlling on-off of each electrode.
In some examples, the relay control unit may belong to a sampling unit, for example may be a relay control circuit in the sampling unit, as described below with reference to fig. 4. As shown in fig. 4, the sampling unit 233 includes one or more of a current detection circuit 2331, a voltage detection circuit 2332, a relay control circuit 2333, a neutral electrode detection circuit 2334, and a temperature detection circuit 2335. The circuitry in sampling unit 233 (parts 2331-2335 in fig. 4) is described below:
the output end of the current detection circuit 2331 is connected with the input end of the central processing unit 232, and is used for detecting the current of each electrode, converting the alternating current signal sampled by each electrode by using the sampling resistor into a direct current level and sending the direct current level to the central processing unit 232;
The output end of the voltage detection circuit 2332 is connected with the input end of the central processing unit 232, and is used for detecting the voltage of the radio frequency output, and the radio frequency output voltage is changed into an alternating current signal with smaller amplitude through the attenuation circuit and is converted into a direct current level by the voltage sampling circuit to be sent to the central processing unit 232;
the output end of the neutral electrode detection circuit 2334 is connected with the input end of the central processing unit 232, and is used for monitoring whether the contact between the neutral electrode and the human body contact point is good in real time, and the current signal passing through the human body and detected by the transformer flows back to the output end, is converted into a direct current level after being sampled and processed, and is sent to the central processing unit 232;
the output end of the temperature detection circuit 2335 is connected with the input end of the central processing unit 232, and is used for reading out the temperature generated by the electrode placed in the human body and sending the temperature to the central processing unit 232;
the relay control circuit 2333 is used for controlling the on-off of the relay according to the current and the voltage of each path of electrode; the relays are in one-to-one correspondence with the electrodes and are used for controlling the on-off of the corresponding electrodes;
It will be appreciated that the circuits 2331-2335 as in fig. 4 can be applied to the various embodiments described above, and are not limited to embodiment three.
Based on the circuits in the sampling units, the central processing unit 232 is configured to calculate the monopole ablation power and the maximum output power according to the current value output by the current detection circuit 2331 and the voltage value output by the voltage detection circuit 2332, in combination with the monopole power value, the adjustment amount corresponding to the temperature adjustment mechanism, and the preset impedance. An output of the central processing unit 232 is connected to an input of the power output board 22.
The output end of the current detection circuit 2331 and the output end of the voltage detection circuit 2332 of the ablation plate 23 are connected with the central processing unit 232 in the scheme, the connection mode can be connected through a lead wire, and the output end of the current detection circuit and the output end of the voltage detection circuit 2332 can also be sent to the central processing unit 232 for digital-analog conversion after the analog-digital change of Bluetooth wifi and the like, so that the power output plate 22 is controlled.
In the scheme, when the monopole ablation power and the maximum output power are calculated, on one hand, the influence of temperature on the overall impedance is fully considered, the regulating quantity corresponding to the temperature regulating mechanism represents the influence quantity (the change quantity of a current value/a voltage value) on the impedance due to temperature change, and on the other hand, the fact that damage to a target object is possibly caused when the temperature is too high is considered. Therefore, by setting the preset temperature range and the protection temperature, the method not only ensures the ablation efficiency, but also can always keep the temperature in the ablation process below the protection temperature, thereby avoiding damage to the target object.
In some examples, as shown in fig. 5, the current detection circuit 2331 includes:
a current sampling circuit 23310 including a sampling resistor to which a signal output from the power board is applied, a voltage signal being formed on the sampling resistor 23310, and this signal being input to a subsequent stage circuit (subsequent differential amplifying circuit 23311);
the input end of the first-stage operational amplifier circuit 23311 is connected with the current sampling circuit of each electrode and is used for amplifying the voltage signal acquired by the sampling resistor and outputting the amplified voltage signal;
the input end of the second-stage operational amplifier rectifying circuit 23312 is connected with the output end of the first-stage operational amplifier rectifying circuit and is used for carrying out half-wave rectification on the amplified voltage signal, filtering out the signal of a negative half shaft, retaining the signal of a positive half shaft and outputting a positive half shaft waveform signal; the positive half-shaft waveform signal is a sine signal with only a positive half shaft;
the input end of the direct current filter circuit 23313 is connected with the output end of the secondary operational amplifier rectifying circuit and is used for filtering the positive half-axis waveform signal output by the rectifying circuit so as to obtain a waveform similar to the direct current signal;
the input end of the follower 23314 is connected with the output end of the direct current filter circuit and is used for isolating the waveform of the approximate direct current signal from front to back, ensuring that the subsequent stage cannot receive the interference of the previous abnormal signal and obtaining a direct current signal with relatively stable voltage, namely a signal with the waveform being nearly linear;
And an input end of the RC filter circuit 23315 is connected with an output end of the follower 23314, and is used for further filtering the signal with the waveform close to linearity to obtain a linear direct current signal with stable voltage, and sending the linear direct current signal to the central processing unit so that the central processing unit determines a current value according to the linear direct current signal.
In the specific implementation, the circuit structure of the current detection circuit 2331 may be as shown in fig. 6, which is not described herein. The current value measured by the sampling resistor is too small, the primary operational amplifier circuit 23311 is required to amplify the current signal, the current signal is rectified into a waveform of a positive half shaft through the secondary operational amplifier rectifier circuit 23312, the waveform is subjected to the direct current filter circuit 23313 to obtain an approximate direct current, the waveform is subjected to the follower 23314 to obtain an approximate linear waveform, and the waveform is subjected to the RC filter circuit 23315 to better perform the filtering function, output the detected current value which is more stable and basically not fluctuated, and finally achieve the purpose of precisely detecting the current.
Further, the preset coefficient in the stable current detection circuit 23316 is associated with the resistance value of the sampling resistor in the current sampling circuit 23310, the amplification factor in the differential amplification circuit 23311, the half-wave rectification coefficient in the rectification circuit 23312, the direct current filter coefficient in the direct current filter circuit 23313, and the RC filter coefficient in the RC filter circuit 23315.
In the example, the current signal to be detected is amplified in a differential amplification mode, and under the condition that the detection precision is unchanged, the detection accuracy of the current signal to be detected is improved. The output current is more stable and basically does not fluctuate through RC filtering, and the quasi-deterministic decline of the detection result due to fluctuation is avoided.
In some examples, as shown in fig. 7, the voltage detection circuit 2332 includes:
the input end of the voltage attenuation circuit 23321 is connected with the voltage to be detected of each electrode and is used for attenuating the voltage signal to be detected, the radio frequency output signal is applied to the attenuation circuit to obtain a voltage attenuated according to a certain proportion, and then the voltage is sent to the subsequent circuit, namely the attenuated voltage signal is output, wherein the attenuation multiple of the voltage attenuation circuit is set by a user;
the input end of the secondary operational amplifier rectifying circuit 23322 is connected with the output end of the voltage attenuation circuit 23321, and is used for carrying out half-wave rectification on the attenuation voltage signal, filtering out the signal of a negative half shaft, retaining the signal of a positive half shaft, rectifying the signal into the waveform of the positive half shaft, and sending the waveform to the direct current filter circuit 23323; the waveform of the positive half shaft is a sine signal with only the positive half shaft;
The input end of the direct current filter circuit 23323 is connected with the output end of the secondary operational amplifier rectifying circuit 23322 and is used for filtering the positive half-axis waveform output by the rectifying circuit 23322 to obtain a waveform similar to a direct current signal, so that the approximate direct current signal is obtained;
the input end of the follower 23324 is connected with the output end of the direct current filter circuit 23323 and is used for isolating the waveform of the approximate direct current signal from front to back, ensuring that the subsequent stage cannot receive the interference of the previous abnormal signal and obtaining a direct current signal with stable voltage, namely, a signal with the waveform being nearly linear;
the input end of the RC filter circuit 23325 is connected with the output end of the follower 23324, and is used for filtering the signal with the waveform close to linearity to further obtain a linear direct current signal with stable voltage, and the linear direct current signal is used for indicating the output voltage of the equipment and is input to the central processing unit 232 for processing; the cpu 232 performs voltage value detection according to the stable linear dc signal, and calculates a voltage value of the detected voltage signal at each electrode according to a preset coefficient.
In the implementation of the present example, the measured voltage value is attenuated by the resistor voltage dividing circuit, because the measured voltage value is too large, and the voltage signal is attenuated in a manner of requiring resistor voltage division, so that the voltage signal is attenuated to a state of being convenient to measure. The waveform is modulated and filtered, so that the voltage for detection is more stable and basically does not fluctuate, and the detection result is prevented from quasi-deterministic decline due to fluctuation.
In detail, the circuit configuration of the voltage detection circuit 2332 may be as shown in fig. 8. The voltage attenuation circuit (resistor divider circuit) 23321 may be shown in a block 7 in fig. 8, the dc filter circuit 23323 may be shown in a block 22, the follower may be shown in a block 23, the RC filter may be shown in a block 24, and the specific structure will not be described here.
Further, the preset coefficient of the voltage detection circuit is related to the attenuation multiple of the voltage attenuation circuit, half-wave rectification of the rectification circuit, the direct current filter coefficient of the direct current filter circuit and the RC filter coefficient of the RC filter circuit.
In some embodiments, the power output board 22 realizes the function of regulating voltage through a set of power supply device, the input end of the power output board is connected with 220V alternating current, the 220V alternating current is converted into 300-400V direct current voltage through a rectifying circuit, the digital quantity is converted into analog quantity through a DA module, the analog quantity is fed back to an SC pin in the DC-DC device, and the DC-DC device is controlled to output 0-48V direct current, and the power output board is connected with an energy storage inductor to output voltage. The output voltage is connected with the power amplifying circuit.
In some examples, the neutral electrode detection circuit 2334, as shown in fig. 9, includes:
the transformer 2341 is used for inducing the current on the negative plate, enabling a current signal flowing through a human body to flow back to the output end through the neutral electrode again, enabling the current to pass through the induction coil and generating an induced current, and outputting a voltage for indicating the induced current to the next stage based on the sampling resistor after the induced current passes through the sampling resistor;
A first-stage operational amplifier circuit 23342 for amplifying the voltage outputted from the transformer 2341 for indicating the induced current by an operational amplifier and sending the amplified voltage to the rectifying circuit 23343;
the input end of the secondary operational amplifier rectifying circuit 23343 is connected with the output end of the primary operational amplifier amplifying circuit 23342, rectifies the amplified current signal, filters out the signal of the negative half shaft, retains the signal of the positive half shaft, rectifies the signal into the waveform of the positive half shaft and sends the waveform to the direct current filter circuit 23344; the waveform of the positive half shaft is a sine signal with only the positive half shaft;
the input end of the direct current filter circuit 23344 is connected with the output end of the rectifying circuit 23343, and the direct current filter circuit is used for filtering the positive half-axis waveform output by the rectifying circuit 23343 to obtain a waveform similar to a direct current signal, so that the approximate direct current signal is obtained;
the input end of the follower 2345 is connected with the output end of the direct current filter circuit 23344, and is used for isolating the waveform of the approximate direct current signal from front to back, ensuring that the subsequent stage cannot receive the interference of the previous abnormal signal, and obtaining a direct current signal with stable voltage, namely, a signal with the waveform being nearly linear;
the input end of the RC filter circuit 23346 is connected to the output end of the follower 2345, and is used for filtering the signal with the waveform close to linearity, so as to further obtain a linear direct current signal with stable voltage, i.e. a stable voltage, and input the linear direct current signal to the central processing unit 232 for processing. The central processing unit 232 performs current value detection according to the stable current, and calculates a current value of the induced current generated by the transformer according to a preset coefficient.
Further, the preset coefficient of the neutral electrode detection circuit is related to the ratio of the transformer sampling, the amplification factor in the differential amplification circuit, the half-wave rectification coefficient in the rectification circuit, the direct current filter coefficient in the direct current filter circuit and the RC filter coefficient in the RC filter circuit.
The current value of the negative plate is conveniently detected by detecting the mutual inductance current of the circuit where the mutual inductor is located and calculating the current of the negative plate. The mutual inductor is a device that senses each other. The transformer has four legs, two of which are connected in series to the current path of the negative plate, and the current of the negative plate passes through the transformer. The current on the channel is overlarge, so that the detection is inconvenient, and the other two feet of the transformer are connected into the circuit to detect the current of the negative plate. As shown in fig. 10, the neutral electrode detection circuit may include a transformer TAK10-050, a sampling resistor R152; the primary operational amplifier method circuit may include an operational amplifier chip U38, where a positive input end of the operational amplifier chip is connected to a sampling resistor R152 via a resistor R220 to obtain a voltage signal for indicating an induced current; the direct current filter circuit can comprise a resistor R156, a filter capacitor C147 and a zener diode D41; the follower may include a chip U40; the RC filter circuit comprises a zener diode D40, a resistor R157 and a filter capacitor C148. As for the connection relationship between the respective circuits, and other circuit elements, reference may be made to the embodiment shown in fig. 10, and a detailed description thereof will be omitted.
In some examples, temperature detection circuit 2335, as shown in fig. 11 and 12, includes:
a temperature sensor 23351 for converting the detected temperature into a current signal by a micro temperature sensor probe inside the catheter and transmitting the current signal to a temperature sensor filter circuit 23352;
the temperature sensor filter circuit 23352 is configured to filter the current signal sent by the temperature sensor 23351, obtain a filtered current signal, and send the filtered current signal to the temperature detection chip 23355;
the cold end compensation temperature sensor 23353 is configured to read the cold end temperature by using the cold end compensation temperature sensor 23353 and send the cold end temperature to the cold end compensation sensor filter circuit 23354; the joint of constantan wire and copper wire is called cold end;
the cold end compensation sensor filter circuit 23354 is configured to filter the cold end temperature signal sent by the cold end compensation temperature sensor 23353, and send the cold end temperature signal to the temperature detection chip 23355;
the temperature detecting chip 23355 is configured to calculate an actual temperature by combining the filtered current signal sent by the temperature sensor filtering circuit 23352 and the filtered cold end temperature signal sent by the cold end compensation sensor filtering circuit 23354, and send the actual temperature to the central processing unit 232 in a register form.
Further, the collection accuracy of the temperature collection circuit 2335 is associated with the temperature sensor 23351, the temperature sensor filter circuit 23352, the temperature detection chip 23355, the cold side compensation temperature sensor 23353, and the cold side compensation sensor filter circuit 53354.
Further, as shown in fig. 13, the central processing unit further includes a memory 2331, a processor 2332, a comparator 23333, and a controller 23334. Optionally, the controller is connected to a relay unit 23335;
the memory 2331 is configured to store a preset energy value E input by a user;
the processor 2332 is configured to receive the current of each electrode sent by the current detection circuit 2331 and the voltage of the total electrode sent by the voltage detection circuit 2332, and calculate the energy value En accumulated and generated in a unit time by combining the serial-parallel connection mode of the sampling units 233;
a comparator 23333, configured to compare the energy value En accumulated and generated in the unit time sent by the processor 2332 with a preset energy value E in the storage device, and output an equal signal when the energy value En accumulated and generated in the unit time is equal to the preset energy value E;
a controller 23334, configured to control the circuit where the relay unit 23335 is located to be disconnected according to the equal signal; the relay units 23335 are in one-to-one correspondence with the electrodes, and the relay units 23335 are used for controlling the on-off of the corresponding electrodes.
When the temperature value monitored by the temperature sensor exceeds the set temperature upper limit value, the relay is directly controlled to be turned off, subsequent ablation is not executed any more, and the protection effect of equipment is achieved.
The relay unit 23335 is configured to divide power provided by the power panel into a plurality of power outputs using a plurality of high-power relays connected in parallel. In the implementation, when a plurality of electrodes need to detect current, a plurality of paths of relays corresponding to each other are correspondingly arranged, and the current detection circuits of the corresponding electrodes are controlled one by one.
As shown in fig. 14, the relay unit includes: relay resistor R1, relay resistor R2, relay resistors R4 and R5, and photoelectric relay U1. The triode Q1 is an NPN triode, and the base electrode of the triode Q1 is connected with the second end of the relay resistor R1; the collector electrode of the triode Q1 is connected with the LEDK end of the photoelectric relay U1; the emitter of the triode Q1 is grounded; a first end of the relay resistor R1 is connected to the control module (for example, may be a central control unit in fig. 13); the second end of the relay resistor R1 is connected with the first end of the relay resistor R5; and the second end of the relay resistor R5 is connected with the emitter of the triode. The first end of the relay resistor R2 is connected with a 12V high-level voltage source AVCC, and the second end of the relay resistor R2 is connected with the LEDA end of the photoelectric relay U1. And a first end of the relay resistor R3 is connected with an OUT1 end of the photoelectric relay U1, and a second end of the relay resistor R3 is connected with the voltage-controlled radio frequency source 1. And a first end of the relay resistor R4 is connected with an OUT2 end of the photoelectric relay U1, and a second end of the relay resistor R4 is connected with an ablation electrode.
In some examples, the power output board includes an AC-DC voltage transformation circuit and a DA control module as shown in fig. 15.
The AC-DC transformation circuit consists of a rectification part circuit and a direct current transformation part circuit; the rectification part circuit is used for being connected with 220VAC commercial power, converting the 220VAC commercial power into direct current voltage from alternating current through a rectifier bridge, and inputting the direct current voltage to the direct current transformation part circuit; the direct-current transformation part circuit is used for converting the direct-current large voltage output by the rectification part circuit into direct-current voltage required by equipment. And the direct-current voltage output by the direct-current transformation part circuit is controlled by an SC pin of the module.
The DA control module comprises a DA chip and an operational amplification chip; the DA chip is in communication connection with the central processing unit 232 of the ablation plate 23 and is used for receiving the target voltage (in the form of digital signals) sent by the central processing unit 232, and converting the digital signals into voltage signals to control the voltage on the SC pin, so as to control the output voltage; the input end of a follower circuit formed by an operational amplifier is connected with the output end of the DA control chip, then the follower sends signals output by the DA control chip to the SC pin, and the follower isolates the front voltage and the rear voltage.
It is to be noted that the present embodiment and the second embodiment are both system examples corresponding to the first embodiment, and can be implemented in cooperation with the first embodiment. The related technical details mentioned in the first embodiment are still valid in this embodiment, and in order to reduce repetition, a detailed description is omitted here. Accordingly, the related art details mentioned in the present embodiment can also be applied to the first embodiment.
The foregoing is merely an embodiment of the present invention, and a specific structure and characteristics of common knowledge in the art, which are well known in the scheme, are not described herein, so that a person of ordinary skill in the art knows all the prior art in the application day or before the priority date of the present invention, and can know all the prior art in the field, and have the capability of applying the conventional experimental means before the date, so that a person of ordinary skill in the art can complete and implement the present embodiment in combination with his own capability in the light of the present application, and some typical known structures or known methods should not be an obstacle for a person of ordinary skill in the art to implement the present application. It should be noted that modifications and improvements can be made by those skilled in the art without departing from the structure of the present invention, and these should also be considered as the scope of the present invention, which does not affect the effect of the implementation of the present invention and the utility of the patent. The protection scope of the present application shall be subject to the content of the claims, and the description of the specific embodiments and the like in the specification can be used for explaining the content of the claims.

Claims (12)

1. A method of regulating power, the method for regulating the output power of an ablation plate, the ablation plate comprising a plurality of electrodes; the method comprises the following steps:
acquiring a real-time current value and a real-time voltage value of each electrode of an ablation plate in an ablation process;
determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value, and determining a designated electrode from the electrodes based on the real-time impedance;
determining a target monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power set;
based on the real-time power of the at least one electrode and the target monopolar power, an input voltage of the ablation plate is adjusted to adjust an output power of the ablation plate.
2. A method of regulating power according to claim 1, wherein determining a designated electrode from said electrodes based on said real-time impedance comprises:
and determining the electrode with the minimum real-time impedance as a designated electrode.
3. A method of regulating power according to claim 1, wherein determining a target monopolar power for at least one of said electrodes based on a real-time impedance of said designated electrode and a preset monopolar power that has been set, comprises:
And determining the target monopolar power of the designated electrode based on the set preset monopolar power.
4. A method of regulating power according to claim 3, wherein determining the target monopolar power for at least one of said electrodes based on the real-time impedance of said designated electrode and the preset monopolar power that has been set, further comprises:
for each other electrode except the designated electrode, calculating a ratio of the real-time impedance of the designated electrode to the real-time impedance of the other electrode, and determining a target monopolar power of the other electrode based on the ratio of the real-time impedances and the target monopolar power of the designated electrode.
5. A method of regulating power according to any one of claims 3 or 4, said determining a target monopolar power for said designated electrode based on said set preset monopolar power, comprising:
acquiring real-time temperature of an ablation object corresponding to the designated electrode in the ablation process;
determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object corresponding to the designated electrode and a preset temperature threshold; the power adjustment value is used for adjusting the real-time temperature of the ablation object corresponding to the designated electrode;
And determining the target monopolar power of the designated electrode based on the preset monopolar power and the power adjustment value.
6. The method of claim 5, wherein the temperature threshold comprises a preset temperature range and a preset protection temperature, and wherein a maximum value of the preset temperature range is less than or equal to the preset protection temperature;
the target monopole power is the sum of the preset monopole power and the power adjustment value;
determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object corresponding to the designated electrode and a preset temperature threshold value, wherein the power adjustment value comprises the following steps:
when the real-time temperature of the specified electrode corresponding to the ablation object is in a preset temperature range, setting a power adjustment value of the specified electrode to 0 so that the target monopolar power is equal to the preset monopolar power;
when the real-time temperature of the specified electrode corresponding to the ablation object is greater than a preset protection temperature, setting a power adjustment value of the specified electrode to be less than 0 so that the target monopolar power is less than the preset monopolar power;
and when the real-time temperature of the specified electrode corresponding to the ablation object is smaller than the minimum value of a preset temperature range, setting the power adjustment value of the specified electrode to be larger than 0 so that the target monopolar power is larger than the preset monopolar power.
7. The method of claim 1, wherein adjusting the input voltage to the ablation plate based on the real-time power of the at least one electrode and the target monopolar power comprises:
determining the sum of target monopolar powers of all the electrodes in the at least one electrode as target total power;
the input voltage to the ablation plate is adjusted based on a difference between a sum of real-time power of all of the at least one electrode and the target total power.
8. The method of adjusting power of claim 7, adjusting the input voltage to the ablation plate based on a current difference between a sum of real-time power of all of the at least one electrode and the target total power, comprising:
determining a sum of historical real-time powers based on the last acquired real-time powers of all the at least one electrode, and determining a historical difference between the sum of historical real-time powers and the target total power;
searching a current power difference value range and a corresponding voltage variation, to which the current difference value belongs, and a historical power difference value range to which the historical difference value belongs in a corresponding relation table of a preset power difference value range and a voltage variation;
If the current difference range is different from the historical power difference range, adjusting the input voltage of the ablation plate according to the corresponding voltage variation;
and if the current difference range is the same as the historical power difference range, acquiring the currently set voltage variation, reducing the currently set voltage variation, and adjusting the input voltage of the ablation plate according to the reduced voltage variation.
9. A method of regulating power according to claim 1, further comprising:
according to the real-time current value and the real-time voltage value of each electrode, calculating to obtain real-time energy generated by each path in unit time;
accumulating the real-time energy generated by each path in each unit time to obtain the total energy generated by the path electrode;
and if the total energy is equal to a preset energy value, adjusting the output power of a circuit where the circuit electrode is positioned to be 0.
10. An ablation system, characterized by: comprises a power output plate and an ablation plate; the ablation plate comprises a central processing unit, a sampling unit and a plurality of electrodes, wherein,
the electrode is connected with one or more ablation objects and is used for ablating the connected ablation objects;
The sampling unit is used for detecting the real-time current value and the real-time voltage value of each electrode and sending the real-time current value and the real-time voltage value to the central processing unit;
the central processing unit is used for: determining the real-time impedance of each electrode according to the real-time current value and the real-time voltage value sent by the sampling unit, and determining a designated electrode from the electrodes based on the real-time impedance; and determining a target electrode monopolar power of at least one of the electrodes based on the real-time impedance of the designated electrode and the preset monopolar power that has been set; and determining a control voltage signal to be transmitted by the ablation plate based on the real-time power of the at least one electrode and the target monopolar power, and transmitting the control voltage signal to a power output plate;
the power output plate is used for determining target voltage according to the control voltage signal sent by the central processing unit and adjusting the output power of the electrode according to the control voltage signal.
11. The system of claim 10, wherein the sampling unit is further configured to detect a real-time temperature of an ablation object to which the designated electrode is connected, and send the real-time temperature to the central processing unit;
The central processing unit is further configured to: determining a power adjustment value of the designated electrode according to a comparison result between the real-time temperature of the ablation object connected with the designated electrode and a preset temperature threshold; and determining a target monopolar power of the designated electrode based on the preset monopolar power and the power adjustment value that have been set; wherein the power adjustment value is used to adjust the real-time temperature of an ablation object connected to the designated electrode.
12. The system of claim 10, wherein the ablation plate further comprises a relay control unit; the relay control unit is connected with the plurality of electrodes and is used for controlling the on-off of each electrode;
the central processing unit is further configured to: according to the real-time current value and the real-time voltage value of each electrode, calculating to obtain real-time energy generated by each path in unit time; the real-time energy generated by each path in each unit time is accumulated to obtain the total energy generated by the path electrode; and if the total energy is equal to a preset energy value, controlling the relay unit to disconnect the circuit electrode so as to adjust the output power of the circuit where the circuit electrode is positioned to be 0.
CN202211074001.1A 2022-09-02 2022-09-02 Method and system for automatically adjusting power Pending CN117679147A (en)

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TW112100739A TWI843390B (en) 2022-09-02 2023-01-07 Power self-adjusting method and ablation system
PCT/CN2023/115536 WO2024046321A1 (en) 2022-09-02 2023-08-29 Method and system for automatic power adjustment, ablation control device, and storage medium

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