CN117643484A

CN117643484A - Cervical cancer detection device and intelligent detection screening method

Info

Publication number: CN117643484A
Application number: CN202410107035.9A
Authority: CN
Inventors: 段朝晖; 徐大宝; 曾真
Original assignee: Hunan Labsci Medical Robot Co ltd
Current assignee: Hunan Labsci Medical Robot Co ltd
Priority date: 2024-01-25
Filing date: 2024-01-25
Publication date: 2024-03-05

Abstract

The invention provides a cervical cancer detection device. The cervical cancer detection device comprises a propulsion tube; a cylinder; a contact; a sampling assembly; the pushing mechanism comprises a connecting rod, a push plate and a sealing tube; the invention also provides an intelligent detection screening management method for cervical cancer, which comprises the following steps: the cervical cancer detection device is used for sampling cervical exfoliated cells of a user; sampling cervical exfoliated cells of a user, and preparing a cell smear; matching information; and collecting images, and performing detection analysis according to the collected data. The method can realize morphological empirical analysis, quantitative analysis of cell morphology and quantitative analysis of cell nucleic acid of single cells, and obtain more objective and accurate detection results through mutual verification by fusion analysis calculation.

Description

Cervical cancer detection device and intelligent detection screening method

Technical Field

The invention relates to the technical field of sampling, in particular to a cervical cancer detection device and an intelligent detection screening method.

Background

In the early diagnosis and screening management process of cervical cancer, cervical epithelial cell tissue fluid of each patient needs to be sampled, and a detection sample is prepared after sampling, so that support is provided for screening detection of cervical cancer.

In the prior art, a vaginal speculum and a sampling tool are needed to be used for sampling, the vaginal speculum is adopted to open the vagina of a patient in advance, then the tail end of the sampling tool is held by hands, and after the front end bristles of the sampling tool penetrate through the vaginal speculum, the front end bristles are aligned to the inner wall of the cervix, and a cervical epithelial cell tissue fluid sample is contacted and taken. This kind of sampling mode, the mode of adoption is too rough, and patient uncomfortable is felt stronger, and the sampling tool stretches into and stretches out the in-process, touches patient's skin inner wall by mistake easily, causes loss and dilution of sample liquid.

Therefore, it is necessary to provide a new cervical cancer detection device and an intelligent detection screening method to solve the above technical problems.

Disclosure of Invention

The invention provides a cervical cancer detection device, which solves the technical problems that in the prior art, a vaginal speculum and a sampling tool are used for sampling, so that the discomfort of a patient is strong, and sampling liquid is easy to lose and dilute.

In order to solve the above technical problems, the present invention provides a cervical cancer detection device comprising:

a propulsion tube;

the limiting cylinder comprises a cylinder body and a fixed shaft, the cylinder body is suspended in the propulsion pipe, and the fixed shaft is fixedly connected with the cylinder body and the propulsion pipe;

the other end of the contact head extends into the pushing tube and is connected with the cylinder body, and the contact head covers the cylinder opening of the cylinder body;

the sampling assembly is arranged in the cylinder body and is arranged towards the contact head;

the pushing mechanism comprises a connecting rod, a pushing plate and a sealing tube, one end of the connecting rod is connected with the sampling assembly, the other end of the connecting rod penetrates through the cylinder body and then extends out of the pushing tube and is fixedly connected with the pushing plate, the sealing tube is arranged around the connecting rod, one end of the sealing tube extends into the pushing tube and then is in sliding connection with the cylinder body, and the other end of the sealing tube is movably connected with the pushing plate;

the protection mechanism comprises a sleeve, a contact layer and a connecting rope, wherein the sleeve is sleeved into the propulsion pipe and surrounds the contact head, the contact layer is stuck in the propulsion pipe and is positioned between the propulsion pipe and the cylinder body, one end of the contact layer extends out of the propulsion pipe and is connected with the sleeve, one end of the connecting rope is connected with the sleeve, and the other end of the connecting rope is bent and extends into the propulsion pipe to be connected with the other end of the contact layer;

the sealing tube is provided with an L-shaped hole, the fixed shaft penetrates through a short side hole of the L-shaped hole and is abutted to the sealing tube, and the connecting ropes and the fixed shaft are distributed in a staggered mode.

Preferably, the protection mechanism further comprises a slip ring slidably mounted in the propulsion tube, and the connection rope is connected with the contact layer through the slip ring.

Preferably, the sampling assembly comprises a liquid storage barrel, a needle tube, a piston and a sampling rod, wherein the liquid storage barrel is slidably arranged in the barrel, the piston is slidably arranged in the liquid storage barrel, the needle tube is communicated with the liquid storage barrel and is arranged towards the contact head, one end of the sampling rod is connected with the piston, and the other end of the sampling rod penetrates through the liquid storage barrel and then is connected with the connecting rod;

a rotating gap is preset between the liquid storage cylinder and the cylinder body, and a T-shaped locking groove is formed in the cylinder body; a locking shaft is fixedly arranged on the liquid storage cylinder; the locking shaft is inserted into the long side groove of the T-shaped locking groove, and the locking shaft is in sliding connection with the T-shaped locking groove.

Preferably, a T-shaped locking groove is formed in the cylinder; a locking shaft is fixedly arranged on the liquid storage cylinder; the locking shaft is inserted into the T-shaped locking groove and is connected in a sliding mode, and the long side groove of the T-shaped locking groove is arranged towards the locking shaft.

Preferably, the pushing mechanism further comprises an elastic piece, and the elastic piece is sleeved on the connecting rod and is elastically connected with the cylinder body and the push plate.

Preferably, the number of the fixed shafts is two, and the cylinder is positioned between the two fixed shafts; the sealing tube is provided with an L-shaped hole, and one fixing shaft is correspondingly arranged with one corresponding L-shaped hole.

Preferably, the contact head comprises a latex head and a latex ring, the latex head is provided with the sampling port, the latex head is connected with the cylinder, and the latex ring is fixedly arranged in the sampling port.

Preferably, a protective cover is fixedly arranged on the sleeve, and the protective cover covers the latex head and is detachably connected with the sleeve.

Preferably, the sleeve is provided with a locking groove structure, and the protection mechanism further comprises a bolt which is in threaded connection with the sleeve;

the connecting rope penetrates through the sleeve and stretches into the locking groove structure, and is wound on the bolt and pressed between the bolt and the locking groove structure.

The invention also provides an intelligent detection screening management method for cervical cancer, which comprises the following steps:

s100, sampling cervical exfoliated cells of a user, and preparing a cell smear; the cervical cancer detection device is used for sampling cervical exfoliated cells of a user;

s200, information matching;

s300, collecting images, and performing detection analysis according to the collected data.

Compared with the related art, the cervical cancer detection device provided by the invention has the following beneficial effects:

when the cervical cancer detection device is used, the contact head is contacted with a detection port of a patient, a user holds the sleeve by one hand and pushes the push plate by the other hand, and as the fixed shaft passes through the short side hole of the L-shaped hole and is abutted against the sealing tube, the push plate pushes the pushing tube and the contact head to advance through the sealing tube and the fixed shaft so that the pushing tube advances relative to the sleeve, the contact layer is gradually unfolded from the inside of the pushing tube and is paved between the pushing tube and the inner skin wall of the patient, and the contact layer adopts a pavement-like advancing mode, so that the pushing tube is not directly contacted with the inner skin wall, and the pushing tube is prevented from contacting and rubbing with the inner skin cavity;

when the contact head enters the inner cavity of a patient and approaches the cervical, the sealing tube is rotated, so that the fixed shaft and the sealing tube rotate relatively in a counter-rotating way, and the fixed shaft enters the long side hole of the L-shaped hole from the short side hole of the L-shaped hole;

continuing pushing the push plate, wherein the push plate drives the connecting rod and the sampling assembly to advance, and the sampling assembly extends out of the sampling port of the contact head so as to sample the cervix; after the sampling is completed, the push plate is pulled back, and the sampling assembly can be retracted into the contact head and the fixed pipe.

Finally realize pushing mechanism drives when advancing of propulsion pipe, the contact layer expands gradually and the laminating is at skin inner wall, and whole in-process sampling subassembly and propulsion pipe can not contact and rub with patient's skin inner wall, can realize better sanitary condition and higher comfort simultaneously, can ensure again that the sampling liquid can not lose and dilute in the sampling subassembly.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a three-dimensional view of a first embodiment of a cervical cancer detection device provided by the present invention;

FIG. 2 is a front view of section A-A of FIG. 1;

FIG. 3 is a top view of the seal tube shown in FIG. 2;

FIG. 4 is an enlarged schematic view of portion B shown in FIG. 2;

FIG. 5 is a top view of the cartridge shown in FIG. 4;

FIG. 6 is a schematic view of the cervical cancer detection device according to the first embodiment of the present invention, wherein (a 1) is a front view of the emulsion head in alignment, (a 2) is a front view of the propulsion tube after the propulsion tube is fed, (a 3) is a front view of the needle tube in extension, (a 4) is a front view of the needle tube in retraction, (b 1) is a top view of the sealing tube in (a 1), (b 2) is a top view of the sealing tube in (a 2), (b 3) is a top view of the sealing tube in (a 3), and (b 4) is a top view of the sealing tube in (a 4);

fig. 7 is a schematic diagram of the movement of the propulsion tube shown in fig. 6, wherein (c 1) is a sectional view of the propulsion tube in the state (a 1), (c 2) is a sectional view of the propulsion tube in the state (a 2), (c 3) is a sectional view of the propulsion tube in the state (a 3), (c 4) is a sectional view of the propulsion tube in the processes (a 3) to (a 4), (d 1) is a plan view of the liquid storage tube in the state (c 2), (d 2) is a plan view of the liquid storage tube in the state (c 3), and (d 3) is a plan view of the liquid storage tube in the state (c 4);

FIG. 8 is a schematic drawing showing the drawing of the pushing tube shown in FIG. 7, wherein (c 5) is a sectional view of the pushing tube during the process from (a 3) to (a 4), (c 6) is a schematic drawing of the rotation of the push plate during the process from (a 3) to (a 4), (c 7) is a sectional view of the reset of the push plate during the process from (a 3) to (a 4), (d 4) is a plan view of the liquid storage barrel in the (c 6) state, and (d 5) is a plan view of the liquid storage barrel in the (c 7) state;

FIG. 9 is a three-dimensional view of a second embodiment of the cervical cancer detection device provided by the invention;

FIG. 10 is a cross-sectional view of the sleeve shown in FIG. 9;

FIG. 11 is a cross-sectional view of the sampling assembly;

fig. 12 is a flowchart of the cervical cancer intelligent detection screening management method provided by the invention.

Reference numerals illustrate:

1. a propulsion tube;

2. a protective mechanism; 21. a sleeve; 22. a contact layer; 23. a slip ring; 24. a connecting rope;

3. a contact; 31. a latex head; 32. a latex ring;

4. a limiting cylinder; 41. a cylinder; 42. a fixed shaft; 43. a T-shaped locking groove;

5. a pushing mechanism; 51. an elastic member; 52. a push plate; 53. a connecting rod; 54. sealing the tube; 540. an L-shaped aperture;

6. a sampling assembly; 61. a liquid storage cylinder; 62. a needle tube; 63. a piston; 64. a sampling rod; 611. a locking shaft;

211. a protective cover;

210. a locking groove structure; 25. and (5) a bolt.

The achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

The invention provides a cervical cancer detection device.

First embodiment

Referring to fig. 1 to 3 in combination, a cervical cancer detection device according to a first embodiment of the present invention includes:

advancing the tube 1;

the limiting cylinder piece 4 comprises a cylinder 41 and a fixed shaft 42, the cylinder 41 is suspended in the propulsion tube 1, and the fixed shaft 42 is fixedly connected with the cylinder 41 and the propulsion tube 1;

the device comprises a contact head 3, wherein a sampling port is formed in one end of the contact head 3, the other end of the contact head 3 stretches into the pushing tube 1 and is connected with the cylinder 41, and the contact head 3 covers a cylinder port of the cylinder 41;

the sampling assembly 6 is arranged in the cylinder 41 and is arranged towards the contact head 3;

the pushing mechanism 5 comprises a connecting rod 53, a pushing plate 52 and a sealing tube 54, one end of the connecting rod 53 is connected with the sampling assembly 6, the other end of the connecting rod 53 penetrates through the cylinder 41 and then extends out of the pushing plate 1 and is fixedly connected with the pushing plate 52, the sealing tube 54 is arranged around the connecting rod 53, one end of the sealing tube 54 extends into the pushing plate 1 and then is in sliding connection with the cylinder 41, and the other end of the sealing tube 54 is movably connected with the pushing plate 52;

the protection mechanism 2 comprises a sleeve 21, a contact layer 22 and a connecting rope 24, wherein the sleeve 21 is sleeved into the propulsion tube 1 and is arranged around the contact head 3, the contact layer 22 is adhered in the propulsion tube 1 and is positioned between the propulsion tube 1 and the cylinder 41, one end of the contact layer 22 extends out of the propulsion tube 1 and then is connected with the sleeve 21, one end of the connecting rope 24 is connected with the sleeve 21, and the other end of the connecting rope 24 is bent and extends into the propulsion tube 1 and is connected with the other end of the contact layer 22;

the sealing tube 54 is provided with an L-shaped hole 540, the fixing shaft 42 passes through a short side hole of the L-shaped hole 540 and abuts against the sealing tube 54, and the connecting rope 24 and the fixing shaft 42 are distributed in a dislocation manner.

In this embodiment, the contact layer 22 is a medical latex sleeve, and is integrally tubular and has an elastic expansion function.

In this embodiment, the movable connection between the seal tube 54 and the push plate 52 means that the push plate 52 can drive the seal tube 54 to move back and forth along the setting direction of the propulsion tube 1, and the push plate 52 cannot drive the seal tube 54 to rotate.

The fact that the connecting ropes 24 are arranged in a staggered manner with respect to the fixed shafts 42 means that the connecting ropes 24 are arranged adjacent to the fixed shafts 42, and the fixed shafts 42 do not interfere with the sliding of the connecting ropes 24 in the arrangement direction.

In this embodiment, a medical lubricant may be applied to the outer ring portion of the contact head 3 and/or the contact layer 22.

Referring to fig. 6, when the cervical cancer detection device is used, the contact head 3 contacts with the detection port of the patient, the user holds the sleeve 21 with one hand and pushes the push plate 52 with the other hand, and as the fixing shaft 42 passes through the short side hole of the L-shaped hole 540 and abuts against the sealing tube 54, the push plate 52 pushes the pushing tube 1 and the contact head 3 to advance through the sealing tube 54 and the fixing shaft 42, so that the pushing tube 1 advances relative to the sleeve 21, the contact layer 22 is gradually spread out from the inside of the pushing tube 1 and is laid between the pushing tube 1 and the skin inner wall of the patient, and the contact layer 22 adopts a similar advancing manner, so that the pushing tube 1 does not directly contact with the skin inner wall, and the pushing tube 1 is prevented from contacting and rubbing with the skin inner wall;

when the contact head 3 enters the inner cavity of the patient and approaches the cervical, the sealing tube 54 is rotated, so that the fixed shaft 42 and the sealing tube 54 rotate relatively in a counter manner, and the fixed shaft 42 enters the long side hole of the L-shaped hole 540 from the short side hole of the L-shaped hole 540;

continuing to push the push plate 52, the push plate 52 drives the connecting rod 53 and the sampling assembly 6 to advance, and the sampling assembly 6 extends out of the sampling port of the contact head 3 so as to sample the cervix; after the sampling is completed, the push plate 52 is pulled back, and the sampling assembly 6 can be retracted into the contact head 3 and the cylinder 41.

Finally realize push mechanism 5 drives when advancing of propulsion pipe 1, contact layer 22 expands gradually and the laminating is at skin inner wall, and whole process sampling assembly 6 and propulsion pipe 1 can not contact and rub with patient's skin inner wall, can realize better sanitary condition and higher comfort simultaneously, can ensure again that the sample liquid can not lose and dilute in the sampling assembly 6.

Referring again to fig. 2, in the present embodiment, the protection mechanism 2 further includes a slip ring 23, the slip ring 23 is slidably mounted in the propulsion tube 1, and the connection rope 24 is connected to the contact layer 22 through the slip ring 23. The slip ring 23 can better ensure the sliding stability of the protection mechanism 2.

When the slip ring 23 slides on the surface of the seal pipe 54, the joint between the propulsion pipe 1, the slip ring 23, and the seal pipe 54 can be sealed.

The number of the connecting ropes 24 may be two, the cylinder 41 is located between the two connecting ropes 24, and two connecting ropes 24 are provided, so that the sliding stability of the protection mechanism 2 can be further ensured.

In one embodiment, the sampling assembly 6 may be a sampler with an electric liquid pumping function.

Referring to fig. 2, 4 and 5 in combination, in another embodiment, the sampling assembly 6 includes a liquid storage barrel 61, a needle tube 62, a piston 63 and a sampling rod 64, the liquid storage barrel 61 is slidably mounted in the cylinder 41, the piston 63 is slidably mounted in the liquid storage barrel 61, the needle tube 62 is communicated with the liquid storage barrel 61 and is disposed towards the contact head 3, one end of the sampling rod 64 is connected with the piston 63, and the other end of the sampling rod 64 penetrates through the liquid storage barrel 61 and is connected with the connecting rod 53;

a rotation gap is preset between the liquid storage barrel 61 and the barrel 41, and a T-shaped locking groove 43 is formed in the barrel 41; a locking shaft 611 is fixedly arranged on the liquid storage barrel 61; the locking shaft 611 is inserted into the long side groove of the T-shaped locking groove 43, and the locking shaft 611 is slidably coupled with the T-shaped locking groove 43.

A rotation gap is reserved between the liquid storage barrel 61 and the barrel 41, so as to provide support for the subsequent rotation of the liquid storage barrel 61 relative to the barrel 41.

Referring to fig. 6 to 8, the fixing shaft 42 enters the long side hole of the L-shaped hole 540 from the short side hole of the L-shaped hole 540; the pushing plate 52 is pushed continuously, and the pushing plate 52 drives the connecting rod 53 and the liquid storage barrel 61 to move forwards.

During the forward movement of the cartridge 61, the locking shaft 611 is aligned with and inserted into the long side groove of the T-shaped locking groove 43;

as shown in fig. 7 (c 3) and (d 2), when the locking shaft 611 enters the middle end of the long side groove of the T-shaped locking groove 43, the needle tube 62 protrudes from the sampling port of the contact head 3 to perform sampling at the cervix;

as shown in fig. 7 (c 4) and (d 3), the push plate 52 drives the connecting rod 53 and the sampling assembly 6 to rotate, and the locking shaft 611 is turned into the short side groove of the T-shaped locking groove 43 and is clamped with the cylinder 41, so as to provide a function of locking the liquid storage barrel 61; providing a locking limit during the sampling process;

as shown in fig. 8, after the sampling is completed, the liquid storage barrel 61 can control the locking shaft 611 to reenter the long-side groove from the short-side groove under the action of manual torsion, the liquid storage barrel 61 releases the relative locking with the cylinder 41, and the liquid storage barrel 61 is pulled back, so that the needle tube 62 is retracted into the cylinder 41, and the needle tube 62 and the inner wall of the skin are prevented from being scratched. (because the device itself is manually controlled and used, and is subject to human factors, tilting is likely to occur during the extraction process, and thus the needle tube 62 needs to be retracted into the device and then removed, avoiding scratching the inner skin wall).

As a preferred form of this embodiment, the needle cannula 62 is of a flat head construction to avoid scoring.

Referring to fig. 2 again, the pushing mechanism 5 further includes an elastic member 51, and the elastic member 51 is sleeved on the connecting rod 53 and elastically connects the cylinder 41 and the push plate 52.

Referring to fig. 7 again, when the push plate 52 moves forward relative to the cylinder 41, the elastic member 51 is compressed to drive the connecting rod 53 to move left, the liquid storage cylinder 61 and the needle tube 62 move forward, and the needle tube 62 moves left from the contact head 3 and extends out for sampling;

after the liquid storage barrel 61 is locked with the short side groove of the T-shaped locking groove 43 by the locking shaft 611, the elastic member 51 pushes the push plate 52 and the connecting rod 53 to move right under the elastic force after the push plate 52 is released, and the piston 63 moves right relative to the liquid storage barrel 61 and completes sampling.

Referring again to fig. 2, as an alternative to this embodiment, the number of the fixing shafts 42 is two, and the cylinder 41 is located between the two fixing shafts 42. The sealing tube 54 may be provided with an L-shaped hole 540, and one of the fixing shafts 42 is disposed corresponding to the corresponding L-shaped hole 540. Two L-shaped holes 540 may be formed in the sealing tube 54, and the fixing shafts 42 and the L-shaped holes 540 are arranged in one-to-one correspondence.

Referring to fig. 4 again, the contact head 3 includes a latex head 31 and a latex ring 32, the latex head 31 is provided with the sampling port, the latex head 31 is connected with the cylinder 41, and the latex ring 32 is fixedly disposed in the sampling port. To provide stable support for extension and retraction of the needle cannula 62.

In this embodiment, the latex ring 32 is in a expandable structure, and when the needle tube 62 is inserted from the central portion of the latex ring 32, the latex ring 32 expands and allows normal passage; the latex ring 32 automatically rebounds when the needle cannula 62 is retracted.

When the device is not in use, the sealing tube 54 cooperates with the latex ring 32 to provide a relatively sealed environment for the contact layer 22, to provide protection for the needle cannula 62 and the contact layer 22 prior to use, and to reduce contact with the outside.

As a preferred alternative of this embodiment, the latex head 31 is screwed with the cylinder 41.

And the latex head 31 is completely shielded at the extending part of the contact layer 22 when the latex head 31 is screwed and installed, so that the support is provided for sealing and preserving the contact layer 22 before use.

The working principle of the cervical cancer detection device provided in this embodiment is as follows:

as shown in fig. 6 (a 1), (b 1) and fig. 7 (c 1), the latex head 31 is aligned with the inner wall of the skin in the initial state, the sleeve 21 is attached to the outer wall of the skin, the contact layer 22 is in the contracted state, and the push plate 52 is in the expanded state relative to the cylinder 41; the fixed shaft 42 is positioned in the short side hole range of the L-shaped hole 540;

one hand holds the sleeve 21 and the other hand holds the push plate 52;

with reference to fig. 6 (a 1) to (a 2) and fig. 7 (c 1) to (c 2), the push plate 52 is manually pushed, the push plate 52 pushes the push tube 1 to advance through the seal tube 54 and the fixed shaft 42 in the locked state, and the push tube 1 slides forward relative to the sleeve 21;

the contact layer 22 gradually extends out of the pushing tube 1 and is paved on the inner skin wall while the pushing tube 1 slides, so that friction generated between the pushing tube 1 and the inner skin wall is reduced, and discomfort brought by the equipment in the use process is reduced;

stopping pushing action when the latex head 31 approaches to the cervical sampling site, and fully expanding the contact layer 22;

referring to fig. 6 (b 1) to (b 2), after the contact layer 22 is fully unfolded, the sealing tube 54 is rotated, the sealing tube 54 drives the L-shaped hole 540 to rotate, so that the fixed shaft 42 and the L-shaped hole 540 rotate relatively, the fixed shaft 42 is switched from the short side hole to the long side hole of the L-shaped hole 540, so that the sealing tube 54 and the fixed shaft 42 are unlocked, and the sealing tube 54 can be telescopically adjusted relative to the fixed shaft 42 and the cylinder 41;

as shown in fig. 6 (a 2) and (b 2) and fig. 7 (c 2) and (d 1), the latex head 31 is positioned at the cervical orifice, the sleeve 21 is attached to the outside of the skin, the contact layer 22 is in a unfolded state, and the push plate 52 is in a unfolded state relative to the cylinder 41; the fixed shaft 42 is positioned in the long side hole range of the L-shaped hole 540;

when the needle tube 62 needs to leak, the pushing plate 52 is pushed continuously, the pushing plate 52 compresses the elastic member 51 and drives the connecting rod 53 to move left, and the sampling rod 64, the piston 63, the liquid storage barrel 61 and the needle tube 62 move left synchronously, as shown in (a 2) to (a 3), (b 2) to (b 3) in fig. 6 and (c 2) to (c 3), (d 1) to (d 2) in fig. 7;

the needle tube 62 moves leftwards and passes through the latex ring 32 and is exposed from the latex head 31, and the exposed length can be in the range of 8 mm-15 mm;

simultaneously with the left movement of the liquid storage barrel 61, the locking shaft 611 slides along the long side groove range of the T-shaped locking groove 43 and enters the switching range of the short side groove;

as shown in fig. 6 (a 3) and (b 3) and fig. 7 (c 3) and (d 2), the latex head 31 is positioned at the cervical orifice, the sleeve 21 is attached to the outside of the skin, the contact layer 22 is in an expanded state, and the push plate 52 is in a compressed state relative to the cylinder 41; the fixed shaft 42 is positioned in the long side hole range of the L-shaped hole 540;

as shown in fig. 6 (a 3) to (a 4), (b 3) to (b 4) and fig. 7 (c 3) to (c 4), (d 2) to (d 3), the push plate 52 is rotated counterclockwise, the connecting rod 53 drives the sampling rod 64, the piston 63 and the liquid storage barrel 61 to rotate counterclockwise integrally, and the liquid storage barrel 61 drives the locking shaft 611 to rotate relative to the T-shaped locking groove 43; the locking shaft 611 enters the short side slot from the long side slot of the T-shaped locking slot 43;

realizing the locking limit between the liquid storage barrel 61 and the barrel 41, and providing stable support for the next liquid pumping and sampling;

as shown in fig. 6 (a 4) and (b 4) and fig. 7 (c 4) and (d 3), the latex head 31 is positioned at the cervical orifice, the sleeve 21 is attached to the outside of the skin, the contact layer 22 is in an expanded state, and the push plate 52 is in a compressed state relative to the cylinder 41; the fixed shaft 42 is positioned in the long side hole range of the L-shaped hole 540;

as shown in fig. 8 (c 5) to (c 7), when sampling is performed, the push plate 52 is released, the elastic member 51 pushes the push plate 52 to move rightward (or the push plate 52 may be pulled to move rightward manually), and the connecting rod 53 drives the sampling rod 64 to move rightward;

due to the locking of the liquid storage barrel 61, the sampling rod 64 drives the piston 63 to move rightwards relative to the liquid storage barrel 61, so that the needle tube 62 is used for sampling and pumping liquid;

with reference to fig. 8 (c 6) to (c 7) and (d 4) to (d 5), after the piston 63 is completely moved to the right, the push plate 52 is manually rotated clockwise, and the connecting rod 53 drives the piston 63 and the liquid storage barrel 61 to integrally rotate clockwise through the sampling rod 64;

the liquid storage barrel 61 drives the locking shaft 611 to rotate relative to the T-shaped locking groove 43, so that unlocking between the locking shaft 611 and the liquid storage barrel 61 is realized, and support is provided for the piston 63 to drive the liquid storage barrel 61 to move right further;

the push plate 52 moves right, the piston 63 pushes the liquid storage barrel 61 to move right synchronously, the locking shaft 611 slides along the long side groove of the T-shaped locking groove 43, the liquid storage barrel 61 synchronously drives the needle tube 62 to move right, so that the needle tube 62 is retracted, and the latex ring 32 automatically contracts and is coated on the needle tube 62;

finally, the extraction of the cervical epithelial cell tissue fluid is completed in the process of recovering the liquid storage barrel 61 from the sampling state to the contracted state, and the retraction of the needle tube 62 is completed before the pushing tube 1 extracts the inner wall of the skin, so that the problem of scratch during the extraction is effectively avoided.

Similarly, after the sampling is completed, one hand holds the sleeve 21 and the other hand pulls the push plate 52, the pushing tube 1 is retracted, so that the pushing tube 1 moves rightwards relative to the sleeve 21 and gradually withdraws from the inner skin wall, and in the process of withdrawing, the expanded contact layer 22 gradually contracts into the pushing tube 1 until the pushing tube 1 completely withdraws from the inner skin wall, and then the sleeve 21 is separated from the inner skin wall; so that friction and discomfort caused by the pushing tube 1 and the inner wall of the skin can be reduced when the pushing tube 1 is sampled out.

After the sampling is completed, the emulsion head 31 can be removed in advance, the needle tube 62 is leaked, the needle tube 62 is aligned to the injection and bearing area, the push plate 52 is manually pushed, the connecting rod 53 drives the piston 63 to move left, and the discharge of the sampled sample is realized.

Second embodiment

Referring to fig. 9 to 11 in combination, another cervical cancer detection device according to a second embodiment of the present invention is provided. The second embodiment is merely a preferred manner of the first embodiment, and implementation of the second embodiment does not affect the implementation of the first embodiment alone.

The cervical cancer detection device according to the second embodiment of the present invention is different in that a protective cover 211 is fixedly provided on the sleeve 21, and the protective cover 211 covers the latex head 31 and is detachably connected to the sleeve 21. The sealing protection of the latex head 31, the latex ring 32 and the contact layer 22 is facilitated.

Referring to fig. 10 to 11 in combination, the sleeve 21 is provided with a locking groove structure 210, the protection mechanism 2 further includes a bolt 25, and the bolt 25 is in threaded connection with the sleeve 21;

the connecting rope 24 penetrates through the sleeve 21 and extends into the locking groove structure 210, and the connecting rope 24 is wound around the bolt 25 and is pressed between the bolt 25 and the locking groove structure 210.

The connection rope 24 is easily removed from the sleeve 21 by the bolts 25.

As a preferred mode of this embodiment, the connecting rod 53 is screwed with the sampling rod 64.

The T-shaped locking groove 43 opens toward one end of the latex head 31.

Therefore, after the latex head 31 is detached from the cylinder 41, the liquid storage barrel 61 can be pushed out along the opening of the cylinder 41, and the sampling rod 64 can be rotatably adjusted after being pushed out, so that the sampling rod 64 and the connecting rod 53 are separated, and the liquid storage barrel 61 is convenient to detach.

Because the sampling equipment is a disposable article, the sampling equipment is mostly directly used as medical waste treatment after being used, the components cannot be recovered, and the manufacturing cost is high; the local parts of the sampling device are not contacted with the skin of a user, and on the premise of ensuring safety, the parts are recycled, disinfected and recycled as much as possible, so that the generation of medical wastes is necessary.

The solution is convenient to disassemble the liquid storage barrel 61 through a thread structure; the contact head 3 which is detachable is matched, so that the contact layer 22 part is separated from the pushing tube 1 part conveniently, and the pushing tube 1 part which is not in direct contact is recovered conveniently.

The invention also provides an intelligent detection screening management method for cervical cancer.

As shown in fig. 12, the cervical cancer intelligent detection screening management method specifically includes the following steps:

s100, sampling cervical exfoliated cells of a user, and preparing a cell smear; wherein, the cervical cancer detection device is used for sampling cervical exfoliated cells;

s200, information matching;

firstly, placing the prepared cell smear on a detection position on a cell analyzer, and matching the cell smear with personal information of a subject;

the personal information of the subject is input into the information input module, wherein the personal information comprises basic diagnosis information such as name, age, menstrual period status, prognosis result, life habit and the like, and the basis can be provided for the judgment and screening of the subsequent detection result through inputting the personal information of the subject;

And starting a switch of the cell analyzer to start detection of the smear, acquiring at least one view image under a microscope in the cell identification module in the detection process, and then collecting complete cell information.

The detection principle of the cervical cancer intelligent detection screening management method is as follows:

the method comprises the steps that a cell sample to be detected is collected through a cell analyzer, the collected picture is transmitted to a computer, medical staff can directly watch the cell picture through a computer display screen, and the medical staff can carry out preliminary judgment through self professional training and experience accumulation of professional knowledge, so that whether a cell to be detected has a lesion or not;

the computer extracts and quantifies the characteristics of the acquired cell pictures to form quantified indexes;

the system correspondingly compares the extracted quantitative index of the cells to be detected with the quantitative index of normal and corresponding type cells after quantifying the indexes, and detects whether the cells are abnormal or not;

the method comprises the steps of detecting the content change of the cell nucleus by a DNA ploidy method, wherein the indexes of the DNA ploidy method mainly comprise the area of the cell nucleus, the average integrated optical density, the smoothness, the ploidy value of the high ploidy, the number of cells and the like;

regularized quantification of DNA doubles detection index: wherein, the DNA ploidy detection index includes, but is not limited to, the area of the cell nucleus, the average integrated optical density, the smoothness, the ploidy value of the high ploidy, the cell number and the like;

in the detection of cellular nucleic acids, the cells to be detected are preferably stained by papanicolaou staining, wherein the staining step comprises: fixation, nuclear staining, cytoplasmic staining and transparency;

when the cell nucleic acid content is analyzed, the cell nucleic acid content is observed by matching with lamplight, wherein the lamplight comprises an infrared light source, an ultraviolet light source and a visible light source; and is provided with an imaging system.

In the process of cell passing through Papanicolaou staining, after being irradiated by an infrared light source and an ultraviolet light source, part of materials in the staining agent can emit infrared light and ultraviolet light with different wavelengths, the cells are imaged by an imaging lens in an imaging system, and the infrared light and the ultraviolet light with different wavelengths can be identified, so that the analysis of the change of cell nucleic acid is facilitated, accurate technical parameters are provided for fusion analysis, and the accuracy of fusion analysis is improved.

The computer can comprehensively judge whether the cell to be detected has lesions or not through quantitative analysis of the cell morphology, quantitative analysis of the cell nucleic acid and self judgment of medical staff, so that the history of purely empirical analysis of the cell is changed, the cytologic analysis is converted into quantitative analysis from purely empirical analysis, and the defects of the independent quantitative analysis method of the nucleic acid and the quantitative analysis method of the cell are overcome, and the quantitative analysis and judgment of the cell morphology, the quantitative analysis of the cell nucleic acid and the quantitative analysis of the cell are integrated, so that the cytopathy analyzed by AI is accurately and objectively changed, and the empirical difference between people of the empirical cytologic analysis method and the defect of the independent quantitative analysis method of the nucleic acid are avoided.

Particularly, the cervical cancer intelligent detection screening management method can also realize morphological empirical analysis, quantitative analysis of cell morphology and quantitative analysis of cell nucleic acid of single cells, and obtain more objective and accurate detection results through mutual verification by fusion analysis and calculation.

The foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the scope of the invention, and all equivalent structural changes made by the specification and drawings of the present invention or direct/indirect application in other related technical fields are included in the scope of the present invention.

Claims

1. A cervical cancer detection device, comprising:

a propulsion tube;

2. The cervical cancer detection device according to claim 1, wherein the guard mechanism further comprises a slip ring slidably mounted in the propulsion tube, the connection cord being connected to the contact layer via the slip ring.

3. The cervical cancer detection device according to claim 2, wherein the sampling assembly comprises a liquid storage barrel, a needle tube, a piston and a sampling rod, the liquid storage barrel is slidably mounted in the barrel, the piston is slidably mounted in the liquid storage barrel, the needle tube is communicated with the liquid storage barrel and is arranged towards the contact head, one end of the sampling rod is connected with the piston, and the other end of the sampling rod penetrates through the liquid storage barrel and is then connected with the connecting rod;

4. The cervical cancer detection device according to claim 3, wherein the pushing mechanism further comprises an elastic member, and the elastic member is sleeved on the connecting rod and elastically connects the cylinder body and the push plate.

5. The cervical cancer detection device according to claim 4, wherein the number of the fixed shafts is two, and the cylinder is located between the two fixed shafts; the sealing tube is provided with an L-shaped hole, and one fixing shaft is correspondingly arranged with one corresponding L-shaped hole.

6. The cervical cancer detection device according to claim 5, wherein the contact head comprises a latex head and a latex ring, the latex head is provided with the sampling port, the latex head is connected with the cylinder, and the latex ring is fixedly arranged in the sampling port.

7. The cervical cancer detection device according to claim 6, wherein a protective cover is fixedly arranged on the sleeve, and the protective cover covers the emulsion head and is detachably connected with the sleeve.

8. The cervical cancer detection device according to claim 7, wherein the sleeve is provided with a locking groove structure, and the protection mechanism further comprises a bolt in threaded connection with the sleeve;

9. The intelligent detection, screening and management method for cervical cancer is characterized by comprising the following steps of:

s100, sampling cervical exfoliated cells of a user, and preparing a cell smear; wherein the cervical cancer detection device according to any one of claims 1 to 8 is used for sampling cervical exfoliated cells;

s200, information matching;