CN117598661A - Contact lens sensor and method for producing the same - Google Patents

Abstract

The application provides a contact lens sensor and a preparation method thereof. Wherein the contact lens sensor comprises: the outer liquid alloy layer and the inner liquid alloy layer form an upper plate-type inner side capacitor structure and a lower plate-type outer side capacitor structure, the inner side capacitor structure comprises an inner side capacitor upper polar plate and an inner side capacitor lower polar plate, and the outer side capacitor structure comprises an outer side capacitor upper polar plate and an outer side capacitor lower polar plate; an inductance coil structure is arranged between the inner side capacitance upper polar plate and the outer side capacitance upper polar plate. An inner side capacitance structure, an outer side capacitance structure and an inductance coil structure are constructed through the outer liquid alloy layer and the inner liquid alloy layer, intraocular pressure is sensed simultaneously through the three sensitive electrical structural elements, the sensitivity of the contact lens sensor is obviously improved, and the signal quality is good.

Description

Contact lens sensor and method for producing the same

Technical Field

The application relates to the technical field of intraocular pressure sensing, in particular to a contact lens sensor and a preparation method thereof.

Background

Intraocular pressure is an important physiological index of the human eye vision system, and observation of intraocular pressure through a continuous intraocular pressure sensing technology has important significance for diagnosis and treatment of eye diseases. Existing continuous intraocular pressure sensing techniques include implantable intraocular pressure sensing and non-invasive intraocular pressure sensing based on contact lenses, which may create irreversible trauma problems, so most select non-invasive intraocular pressure sensing based on contact lenses.

The contact lens sensor based on the electrical principle comprises a contact lens sensor based on a miniature resistance strain gauge, a inductance-variable LC type, a CLC type or CLCL type contact lens sensor based on a copper material, a inductance-variable LC type intraocular pressure sensor based on a liquid alloy material and the like.

The contact lens sensor based on the miniature resistance strain gauge is integrated with an ASIC module, so that the sensor has high thickness and high rigidity, and the comfort level of the sensitivity machine is poor. The sensor based on copper material and prepared by the thermoplastic molding mode is wrinkled, and cannot meet the safety wearing requirement of human biological eyeballs, and the sensor is thicker in thickness due to the principle of variable-interval capacitance, and a lead bonding mode is adopted when upper and lower pole plates of the capacitance are coupled with an inductance coil, so that the process difficulty is high, and meanwhile, the rigidity is high, and the sensitivity is low. While the liquid alloy material-based variinductance LC intraocular pressure sensor has reduced rigidity, the sensitivity is still to be further improved; meanwhile, the variable inductance LC intraocular pressure sensor based on the liquid alloy material has certain disadvantages in the manufacturing process due to the use of various material elements, the adoption of a coil preparation method based on micro-channel liquid alloy injection and the subsequent patch capacitance penetrating coupling process, so that the success rate of the preparation method is low, the efficiency is low, the mass production is difficult, and the like.

Disclosure of Invention

The application provides a contact lens sensor and a preparation method thereof, so as to improve sensitivity of intraocular pressure sensing. The technical scheme of the application is as follows:

in a first aspect, embodiments of the present application provide a contact lens sensor comprising: the outer liquid alloy layer and the inner liquid alloy layer form an upper plate-type inner side capacitor structure and a lower plate-type outer side capacitor structure, the inner side capacitor structure comprises an inner side capacitor upper polar plate and an inner side capacitor lower polar plate, and the outer side capacitor structure comprises an outer side capacitor upper polar plate and an outer side capacitor lower polar plate; an inductance coil structure is arranged between the inner side capacitance upper polar plate and the outer side capacitance upper polar plate.

In some embodiments of the present application, an inductor structure is disposed between the inner capacitive bottom plate and the outer capacitive bottom plate.

In some embodiments of the present application, the inductor coil structure is a multi-turn annular liquid alloy coil.

In some embodiments of the present application, the multi-turn annular liquid alloy coil is counter-clockwise or clockwise-wound.

In some embodiments of the present application, the outer film layer, the middle film layer, and the inner film layer are all silicone layers.

In some embodiments of the present application, the number of turns of the multi-turn annular liquid alloy coil ranges from 4 turns to 16 turns, the coil width of the multi-turn annular liquid alloy coil ranges from 50 μm to 400 μm, the coil pitch of the multi-turn annular liquid alloy coil ranges from 10 μm to 200 μm, and the coil distribution diameter of the multi-turn annular liquid alloy coil ranges from 6.5mm to 11.2mm.

In some embodiments of the present application, the capacitance diameter distribution range of the inner capacitance structure is 4.5mm to 6.5mm; the capacitance diameter distribution range of the outer capacitance structure is 11.2 mm-14.4 mm.

In a second aspect, embodiments of the present application provide a method for manufacturing a contact lens sensor, including:

the reverse molding of the silicon rubber is realized through the first contact lens female die and the contact lens male die, so that an inner film layer is formed;

forming an inner liquid alloy layer on a first auxiliary film by a direct-writing printing mode, and then integrating the inner liquid alloy layer on the upper surface of the inner film layer in a transfer printing mode by a water transfer printing mode to obtain a two-layer structure;

performing reverse molding of silicon rubber on the upper surface of the two-layer structure through the second contact lens female die and the contact lens male die to form an intermediate film layer, so as to obtain a three-layer structure;

forming an outer liquid alloy layer on a second auxiliary film by a direct-writing printing mode, and integrating the outer liquid alloy layer on the upper surface of the middle film layer of the three-layer structure in a transfer printing mode by a water transfer printing mode to obtain a four-layer structure;

performing reverse molding of silicon rubber on the upper surface of the four-layer structure through a third contact lens female die and the contact lens male die to form an outer film layer, so as to obtain a five-layer structure;

and demolding the five-layer structure from the contact lens male die to obtain the contact lens sensor.

In some embodiments of the present application, the forming an inner liquid alloy layer on a first auxiliary film by direct writing printing, and then transferring the inner liquid alloy layer to the upper surface of the inner film layer by water transfer printing to obtain a two-layer structure includes:

forming an inner liquid alloy layer on the first auxiliary film by using a direct writing printing mode;

placing the first auxiliary film forming the inner liquid alloy layer in water to enable the first auxiliary film to be dissolved and softened into gel state, so as to obtain a gel state film printed with the inner liquid alloy layer;

the contact lens male die provided with the inner film layer is reversely arranged above the gel-state film printed with the inner liquid alloy layer and moves downwards until the gel-state film printed with the inner liquid alloy layer is conformally transferred to the surface of the contact lens male die;

placing the contact lens male die vertically and placing the contact lens male die in water until the gel-state film is completely dissolved;

and taking the contact lens male die out of the water to finish transfer printing and integration of the inner liquid alloy layer on the upper surface of the inner film layer, thereby obtaining a two-layer structure.

In some embodiments of the present application, the first auxiliary film is any one of a PVA film, a pectin film, and a lotus root starch gel film.

The technical scheme provided by the embodiment of the application at least brings the following beneficial effects:

along with the rise of intraocular pressure, the cornea of the eye generates expansion strain, the expansion strain is transmitted to the contact lens sensor, and the outer liquid alloy layer and the inner liquid alloy layer in the contact lens sensor generate tensile strain, so that the capacitance value generated by the capacitance structure and the inductance value generated by the inductance coil structure are increased simultaneously, the simultaneous double-sensitivity sensing of capacitance and inductance is realized, and the sensitivity of intraocular pressure sensing is obviously improved. Meanwhile, the preparation method of the contact lens is based on the treatment method of liquid alloy water transfer printing of a soluble mask, namely, a liquid alloy direct-writing printing technology is adopted to print liquid alloy on the surface of a soluble auxiliary film, and then a liquid alloy graph is transferred to the surface of a curved film of a contact lens sensor through a die water transfer printing technology, so that the preparation method is simple in process principle, less in flow, high in success rate, high in efficiency, easy to integrate with a pupil production line and the like, and is suitable for mass production.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the application and together with the description, serve to explain the principles of the application and do not constitute an undue limitation on the application.

Fig. 1 is an exploded view of a contact lens sensor, according to an exemplary embodiment.

Fig. 2 is a top view of the contact lens sensor shown in fig. 1.

Fig. 3 is a circuit block diagram of the CLC type of contact lens sensor shown in fig. 1.

Fig. 4 is a schematic diagram illustrating the composition of a wireless passive sensing system, according to an exemplary embodiment.

Fig. 5 is a graph of the tensile strain change trend of the contact lens sensor shown in fig. 1.

Fig. 6 is a circuit configuration diagram of a CLCL type of contact lens sensor according to another exemplary embodiment.

Fig. 7 is a layout view of the loop of the multi-turn annular liquid alloy coil of the contact lens sensor of fig. 1.

Fig. 8 is a flow chart illustrating a method of preparing a contact lens sensor according to an exemplary embodiment.

Fig. 9 is a specific process flow diagram according to the preparation method shown in fig. 8.

Fig. 10 is a process flow diagram of a water transfer process according to the preparation method shown in fig. 8.

Detailed Description

In order to enable those skilled in the art to better understand the technical solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings.

In the description of the present application, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate an orientation or a positional relationship based on that shown in the drawings, merely for convenience of description and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present application. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the terms in this application will be understood by those of ordinary skill in the art in a specific context.

Fig. 1 is an exploded view of a contact lens sensor according to one embodiment of the present application, and fig. 2 is a top view of the contact lens sensor. As shown in fig. 1 and 2, the contact lens sensor includes: the outer thin film layer 1, the outer liquid alloy layer 2, the middle thin film layer 3, the inner liquid alloy layer 4 and the inner thin film layer 5 which are sequentially stacked, wherein the outer liquid alloy layer 2 and the inner liquid alloy layer 4 form an upper plate-type inner side capacitor structure and a lower plate-type outer side capacitor structure, the inner side capacitor structure comprises an inner side capacitor upper plate 21 and an inner side capacitor lower plate 41, and the outer side capacitor structure comprises an outer side capacitor upper plate 22 and an outer side capacitor lower plate 42. An inductor structure 23 is provided between the inner capacitor upper plate 21 and the outer capacitor upper plate 22, and the inner capacitor lower plate 41 and the outer capacitor lower plate 42 are connected by a wire. As shown in fig. 3, the contact lens sensor of the present embodiment has a CLC-type circuit structure.

In this embodiment, the outer liquid alloy layer 2 and the inner liquid alloy layer 4 form an inner capacitance structure and an outer capacitance structure of upper and lower plates respectively at an inner position and an outer position corresponding to the contact lens.

As an application example, as shown in fig. 4, the contact lens sensor is applied to a wireless passive sensing system, the wireless passive sensing system further comprises a network analyzer and a reading device, the external network analyzer is electrically connected with the reading device through a radio frequency connecting wire, the reading device and the contact lens sensor form a wireless magnetic coupling loop, and the resonance frequency of the contact lens sensor can be monitored, so that the perception of intraocular pressure is realized.

As the eye pressure increases, the cornea of the eye develops an expansive strain, which can be transferred through the tear film layer to the contact lens sensor, where the electrical sensing elements formed from the liquid alloy develop a tensile strain, i.e., the outer liquid alloy layer 2 and the inner liquid alloy layer 4 of the contact lens sensor develop a tensile strain.

As shown in fig. 5, the inductor structure 23 is tensile strained, the diameter increases (e.g., D1 to d1+Δd) from (a) in fig. 5 to (b) in fig. 5, and the inductance LS increases; at the same time, the inner capacitor structure and the outer capacitor structure (i.e., C1 and C2) also generate tensile strain, the areas of the plates of the inner capacitor structure and the outer capacitor structure (i.e., the inner capacitor upper plate 21, the outer capacitor upper plate 22, the inner capacitor lower plate 41 and the outer capacitor lower plate 42) are increased due to stretching (e.g., S1 is changed to s1+Δs1 and S2 is changed to s2+Δs2), and the capacitance values of both capacitors C1 and C2 are increased.

The inductance value and the capacitance value are increased at the same time, so that the resonance frequency of an electrical loop of the contact lens sensor is obviously reduced under the action of intraocular pressure boosting, the change of the resonance frequency of the contact lens sensor is monitored through a network analyzer, thereby realizing perception of intraocular pressure, and obviously improving the sensitivity of intraocular pressure sensing.

According to the contact lens sensor, the inner side capacitance structure, the outer side capacitance structure and the inductance coil structure are constructed through the outer liquid alloy layer and the inner liquid alloy layer, the intraocular pressure is sensed simultaneously through the three sensitive electrical structural elements, the sensitivity of the contact lens sensor is obviously improved, and the signal quality is good.

Further, in some embodiments, an inductor structure is also disposed between the inner bottom capacitor plate 41 and the outer bottom capacitor plate 42, that is, the inner bottom capacitor plate 41 and the outer bottom capacitor plate 42 are connected by the inductor structure, and the circuit structure of the contact lens sensor is the CLCL circuit structure as shown in fig. 6.

An inner side capacitance structure, an outer side capacitance structure and two inductance coil structures are constructed through the outer liquid alloy layer and the inner liquid alloy layer, intraocular pressure is sensed simultaneously through the four sensitive electrical structural elements, and the sensitivity of the contact lens sensor is further improved.

In some embodiments, as shown in fig. 2, the inductance coil structure is a multi-turn annular liquid alloy coil, the number of turns of the multi-turn annular liquid alloy coil ranges from 4 turns to 16 turns, the coil width of the multi-turn annular liquid alloy coil ranges from 50 μm to 400 μm, the coil pitch of the multi-turn annular liquid alloy coil ranges from 10 μm to 200 μm, and the coil distribution diameter of the multi-turn annular liquid alloy coil ranges from 6.5mm to 11.2mm. The multi-ring annular liquid alloy coil provided by the embodiment of the application is matched with the structural layout of the contact lens, and is simple in structure and easy to realize.

As shown in (a) and (b) of fig. 7, as two possible implementations, the multi-turn annular liquid alloy coil may be in a counterclockwise-surrounding layout or a clockwise-surrounding layout, and the sensing effect is the same, without limitation.

In some embodiments, the outer film layer, the middle film layer and the inner film layer are all made of silica gel, and the process of silica gel is relatively mature and has high reliability; as one example, the silicone material may be selected from implantable medical silicone rubber materials. The outer film layer, the middle film layer and the inner film layer can also be made of other soft materials suitable for preparing contact lenses, without limitation.

The liquid alloy used for the outer liquid alloy layer 2 and the inner liquid alloy layer 4 may be gallium indium tin alloy (Ga-In-Sn), eutectic gallium indium (EGaIn), or the like.

The main parameters of the contact lens of the embodiments of the present application are preferably designed as follows:

the capacitance diameter distribution range of the inner capacitance structure is 4.5 mm-6.5 mm; the capacitance diameter distribution range of the outer capacitance structure is 11.2 mm-14.4 mm.

The total thickness range of the contact lens is: 150-400 μm; the diameter range of the contact lens is as follows: 13.2 mm-15 mm; the radius of curvature of the contact lens ranges from: 7.6 mm-8.8 mm.

The thickness ranges of the outer liquid alloy layer 2 and the inner liquid alloy layer 4 are as follows: 10-200 mu m; the thickness of the intermediate thin film layer 3 (i.e., the capacitor plate pitch) ranges from: 2-40 μm.

The resonant frequency range of the contact lens sensor is: 10 MHz-2 GHz, and the quality coefficient range is as follows: 10 to 200.

According to preferred ranges of the main parameters of the contact lens, the resulting contact lens sensor performs better.

Corresponding to the contact lens sensor, the embodiment of the application also provides a preparation method of the contact lens sensor, and fig. 8 is a flowchart of the preparation method, including the following steps:

and step S101, the reverse molding of the silicon rubber is realized through the first contact lens female die and the contact lens male die, and an inner film layer is formed.

In this embodiment, the outer film layer, the middle film layer and the inner film layer are all made of silica gel, that is, the inner film layer is an inner silica gel layer, the middle film layer is an intermediate silica gel layer, and the outer film layer is an outer silica gel layer; and a CLC type contact lens sensor is prepared as an example.

As in (i) of fig. 9, the first contact lens female die and the contact lens male die are subjected to reverse molding of the silicone rubber, that is, the liquid silicone rubber is poured between the first contact lens female die and the contact lens male die, and then the silicone rubber layer is formed by heat curing, and the cured silicone rubber layer is released from the first contact lens female die and attached to the contact lens male die surface to obtain the inner silicone rubber layer.

Step S102, forming an inner liquid alloy layer on the first auxiliary film by using a direct writing printing mode, and then integrating the inner liquid alloy layer on the upper surface of the inner film layer in a transfer printing mode by using a water transfer printing mode to obtain a two-layer structure.

The upper surface of the inner film layer refers to the outer side surface of the convex side of the inner film layer of the bowl-shaped structure.

It should be noted that, the first auxiliary film in the embodiment of the present application is a flexible and stretchable substance or film that can be dissolved in gel state by water, such as PVA film, pectin, lotus root starch gel, etc., and the corresponding film is formed on the flexible silicone rubber substrate by spin coating, etc., and then is used for the water transfer printing preparation of the liquid alloy.

Optionally, the first auxiliary film in the embodiments of the present application may be any one of a PVA film, a pectin film, and a lotus root starch gel film.

As in (ii) of fig. 9, the liquid alloy is patterned on the PVA film surface by direct write printing, the printed pattern is referred to the pattern of the inner liquid alloy layer, and the printed liquid alloy pattern is transferred and integrated onto the upper surface of the inner silicone rubber layer via a water transfer process.

And step S103, performing reverse molding of the silicon rubber on the upper surface of the two-layer structure through the second contact lens female die and the contact lens male die to form an intermediate film layer, so as to obtain a three-layer structure.

As in (iii) of fig. 9, the patterned inner silicone rubber layer of (ii) is placed in a second contact lens mold, a similar operation as in (i) is repeated, i.e., the step of cast coupling curing the silicone rubber, forming an intermediate silicone rubber layer, and encapsulating the inner liquid alloy layer.

And step S104, forming an outer liquid alloy layer on the second auxiliary film by using a direct-writing printing mode, and then integrating the outer liquid alloy layer on the upper surface of the middle film layer of the three-layer structure in a transfer printing mode by using a water transfer printing mode to obtain a four-layer structure.

As in (iv) of fig. 9, the device after encapsulation in (iii) is patterned with the outer liquid alloy layer on the surface of the intermediate silicone rubber layer using the same water transfer integration process as in (ii).

And step S105, performing reverse molding of the silicon rubber on the upper surface of the four-layer structure through the third contact lens female die and the contact lens male die to form an outer film layer, so as to obtain a five-layer structure.

As in (v) of fig. 9, the water transferred device of (iv) is placed in a third contact lens mold, the outer liquid alloy layer is encapsulated using a procedure similar to the reverse of (i), an outer silicone rubber layer is prepared, and the third contact lens mold is removed.

And step S106, demolding the five-layer structure from the contact lens male die to obtain the contact lens sensor.

As in (vi) of fig. 9, the device of (v) is released from the contact lens punch to produce a liquid alloyed contact lens sensor.

According to the preparation method of the contact lens sensor, a treatment method based on soluble mask liquid alloy water transfer printing is adopted, namely, a liquid alloy printing technology is adopted to print the surfaces of a PVA film or other gel films which are flexible and stretchable in plane, soluble in the PVA film or other gel films and the like, then a plane liquid alloy pattern is transferred to the surface of a formed curved film layer through a die water transfer printing mode, and then the contact lens sensor is formed through reverse die encapsulation. The preparation method has the technical advantages of simple process principle, less flow, high success rate, high efficiency, easy integration with a pupil production line and the like, mass production and the like, and the prepared contact lens sensor has the advantages of high sensitivity, good signal quality and the like.

In addition, in steps S102 and S104, a water transfer process is adopted, and optionally, as shown in fig. 10, the water transfer process includes the following steps:

(i) And placing the planar PVA film on a liquid alloy direct-writing printer, and printing the liquid alloy on the surface of the PVA film in a direct-writing printing mode according to the design pattern of the liquid alloy layer (the inner liquid alloy layer or the outer liquid alloy layer).

(ii) The PVA film containing the pattern obtained in the step (i) is placed under water for 5 minutes at normal temperature, and the PVA film is gradually dissolved in water and softened into gel state.

(iii) Placing a contact lens stamp of the silicone-containing rubber layer (inner rubber layer or intermediate rubber layer) over the gel-state liquid alloy-containing pattern obtained in (ii), the contact lens stamp being moved downwardly so that the entire conformal transfer is made to the contact lens stamp surface.

(iv) The entire structure after the water transfer printing of (iii) is placed vertically, and undissolved PVA gel is stored above the structure.

(v) And (3) the whole body after the transfer printing of the step (iv) is placed in warm water at 50 ℃ for 10min again, and the PVA gel is dissolved.

(vi) And (v) taking out the whole PVA gel after dissolution from the warm water to obtain a liquid alloy pattern (an inner liquid alloy layer or an outer liquid alloy layer) after transfer printing on the surface of the silicon rubber layer (an inner rubber layer or an intermediate rubber layer).

According to the above water transfer printing process step, in step S102, an inner liquid alloy layer is formed on the first auxiliary film by direct writing printing, and then the inner liquid alloy layer is transferred and integrated on the upper surface of the inner film layer by water transfer printing, so as to obtain a two-layer structure, which comprises the following steps:

forming an inner liquid alloy layer on the first auxiliary film by using a direct writing printing mode;

placing the first auxiliary film forming the inner liquid alloy layer in water, and gradually dissolving and softening the first auxiliary film into gel state in the water to obtain a gel state film printed with the inner liquid alloy layer;

the contact lens male die provided with the inner film layer is reversely arranged above the gel-state film printed with the inner liquid alloy layer and moves downwards until the gel-state film printed with the inner liquid alloy layer is conformally transferred to the surface of the contact lens male die;

placing the contact lens male die vertically and placing the contact lens male die in water until the gel-state film is completely dissolved;

and taking the contact lens male die out of the water to finish transfer printing and integration of the inner liquid alloy layer on the upper surface of the inner film layer, thereby obtaining a two-layer structure.

In the same way, according to the above water transfer process step, in step S104, an outer liquid alloy layer is formed on the second auxiliary film by direct writing printing, and then the outer liquid alloy layer is transferred and integrated onto the upper surface of the middle film layer of the three-layer structure by water transfer, so as to obtain a four-layer structure, which comprises the following steps:

and forming an inner liquid alloy layer on the second auxiliary film by using a direct writing printing mode.

Placing the second auxiliary film forming the inner liquid alloy layer in water, and gradually dissolving and softening the second auxiliary film into gel state in the water to obtain a gel state film printed with the outer liquid alloy layer;

and (3) the contact lens male die provided with the intermediate film layer is reversely arranged above the gel-state film printed with the outer liquid alloy layer and moves downwards until the gel-state film printed with the outer liquid alloy layer is conformally transferred to the surface of the contact lens male die.

Placing the contact lens male die vertically and placing the contact lens male die in water until the gel-state film is completely dissolved;

and taking the contact lens male die out of the water to finish the transfer printing of the outer liquid alloy layer to the upper surface of the middle film layer, thereby obtaining a four-layer structure.

The water transfer printing process method adopted by the embodiment of the application has the advantages of simple process principle, less flow, high success rate and high efficiency, and is suitable for mass production.

In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

It should also be noted that the exemplary embodiments mentioned in this disclosure describe some methods or systems based on a series of steps or devices. However, the present invention is not limited to the order of the above-described steps, that is, the steps may be performed in the order mentioned in the embodiments, or may be performed in a different order from the order in the embodiments, or several steps may be performed simultaneously.

Other embodiments of the present application will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. This application is intended to cover any variations, uses, or adaptations of the application following, in general, the principles of the application and including such departures from the present disclosure as come within known or customary practice within the art to which the application pertains. The specification and examples are to be regarded in an illustrative manner only.

It is to be understood that the present application is not limited to the precise arrangements and instrumentalities shown in the drawings, which have been described above, and that various modifications and changes may be effected without departing from the scope thereof. The scope of the application is limited only by the appended claims.

Claims (10)

1. A contact lens sensor, comprising: the outer liquid alloy layer and the inner liquid alloy layer form an upper plate-type inner side capacitor structure and a lower plate-type outer side capacitor structure, the inner side capacitor structure comprises an inner side capacitor upper polar plate and an inner side capacitor lower polar plate, and the outer side capacitor structure comprises an outer side capacitor upper polar plate and an outer side capacitor lower polar plate; an inductance coil structure is arranged between the inner side capacitance upper polar plate and the outer side capacitance upper polar plate.

2. The contact lens sensor of claim 1, wherein an inductor structure is disposed between the inner capacitive bottom plate and the outer capacitive bottom plate.

3. The contact lens sensor of claim 1 or 2, wherein the inductor coil structure is a multi-turn annular liquid alloy coil.

4. A contact lens sensor according to claim 3, wherein the multi-turn annular liquid alloy coil is counter-clockwise or clockwise-wound.

5. The contact lens sensor of claim 1, wherein the outer film layer, the middle film layer, and the inner film layer are all silicone layers.

6. A contact lens sensor according to claim 3, wherein the number of turns of the multi-turn annular liquid alloy coil is in the range of 4-16 turns, the coil width of the multi-turn annular liquid alloy coil is in the range of 50-400 μm, the coil pitch of the multi-turn annular liquid alloy coil is in the range of 10-200 μm, and the coil distribution diameter of the multi-turn annular liquid alloy coil is in the range of 6.5-11.2 mm.

7. The contact lens sensor of claim 1 or 2, wherein the capacitance diameter distribution of the inner capacitance structure ranges from 4.5mm to 6.5mm; the capacitance diameter distribution range of the outer capacitance structure is 11.2 mm-14.4 mm.

8. A method of making a contact lens sensor comprising:

the reverse molding of the silicon rubber is realized through the first contact lens female die and the contact lens male die, so that an inner film layer is formed;

forming an inner liquid alloy layer on a first auxiliary film by a direct-writing printing mode, and then integrating the inner liquid alloy layer on the upper surface of the inner film layer in a transfer printing mode by a water transfer printing mode to obtain a two-layer structure;

performing reverse molding of silicon rubber on the upper surface of the two-layer structure through the second contact lens female die and the contact lens male die to form an intermediate film layer, so as to obtain a three-layer structure;

forming an outer liquid alloy layer on a second auxiliary film by a direct-writing printing mode, and integrating the outer liquid alloy layer on the upper surface of the middle film layer of the three-layer structure in a transfer printing mode by a water transfer printing mode to obtain a four-layer structure;

performing reverse molding of silicon rubber on the upper surface of the four-layer structure through a third contact lens female die and the contact lens male die to form an outer film layer, so as to obtain a five-layer structure;

and demolding the five-layer structure from the contact lens male die to obtain the contact lens sensor.

9. The method according to claim 8, wherein forming an inner liquid alloy layer on the first auxiliary film by direct writing printing, and transferring and integrating the inner liquid alloy layer onto the upper surface of the inner film layer by water transfer printing to obtain a two-layer structure, comprises:

forming an inner liquid alloy layer on the first auxiliary film by using a direct writing printing mode;

placing the first auxiliary film forming the inner liquid alloy layer in water to enable the first auxiliary film to be dissolved and softened into gel state, so as to obtain a gel state film printed with the inner liquid alloy layer;

the contact lens male die provided with the inner film layer is reversely arranged above the gel-state film printed with the inner liquid alloy layer and moves downwards until the gel-state film printed with the inner liquid alloy layer is conformally transferred to the surface of the contact lens male die;

placing the contact lens male die vertically and placing the contact lens male die in water until the gel-state film is completely dissolved;

and taking the contact lens male die out of the water to finish transfer printing and integration of the inner liquid alloy layer on the upper surface of the inner film layer, thereby obtaining a two-layer structure.

10. The method according to claim 9, wherein the first auxiliary film is any one of PVA film, pectin film, and lotus root starch gel film.