CN1175858C - 治疗烧烫伤的中药酊剂及其制备方法 - Google Patents
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Abstract
本发明涉及治疗烧烫伤的中药酊剂及其制备方法，是利用中药材按鲜虎杖根70～100，孩儿茶10～13，冰片5～7组方，按一定配比量加入95%医用酒精浸泡，制成可直接喷洒于烧烫伤创面的酊剂。具有制备成本低，使用方便，适用于身体各部位、各种烧烫伤的治疗，尤其是新鲜III度和II度大面积烧烫创面的治疗，具有喷涂疼痛感轻、收敛结痂快、消炎抗感染、愈合疤痕少而小、疗程较短等显著效果。
Description
所属技术领域
本发明涉及一种治疗烧烫伤的中药酊剂及其制备方法。
背景技术
烧烫伤是因热力、火焰、灼热的气体、液体或固体作用于人体而引起的损伤性疾病，通常还包括化学性烧伤、放射性烧伤、电击伤、强热、电、化学物质、放射线作用于人体，超过人的耐受能力，使人体皮肉弥烂而致病，轻者仅伤及皮肤或肉体，重者则危及生命。烧烫伤的诊断并不难，综合烧伤的面积(中国九分法、手掌法))及烧伤的深度(I度、潜II度、深II度、III度)，可估计出烧烫的程度，一般认为总面积在9％以下的II度为轻度烧伤，总面积在10％-29％或III度为中度烧伤，总面积在30％以上的为重度烧伤。对于轻度烧伤病人，一般以外治为主，保护创面防止感染，促进创口愈合。对于重度烧伤者则应用现代医学方法，采取镇痛、抗炎、补液、抗感染、抗休克等对症处理措施进行治疗。
目前公知的临床治疗烧烫伤的药品有两类：一类是京万红烫伤膏、美宝烧烫膏、成田烧烫膏等膏剂，其主要缺陷是不适于大面积患者使用，由于患者烧烫部位疼痛无比，使用膏剂涂搽烧烫创面时，患者难以耐受；同时烧烫创面具有不同渗出，膏剂不能充分附着于创面，因此必须加压包扎，换药时，包扎材料和膏剂容易粘连创面，容易拉伤创面造成出血、感染，更易留下疤痕或增生，使得创面结痂缓慢，疗程加长，因此膏剂一般只适用于小面积轻度烫伤。另一类是制加酊、烫可喷等酊剂，其主要缺陷是治疗后容易形成烧烫伤疤痕或增生，甚至造成先治疗后植皮的不良后果；对于大面积患者治疗费用高，少则几千元，多则上万元。
中医认为，虎杖根性味苦、平，具有祛风、利湿、破淤、通经之功效，可以用来收敛止血，治疗火伤。实验表明，虎杖根含游离蒽醌及蒽醌疳，主要为大黄素、大黄素申醚和大黄酚以及蒽疳，虎杖煎液具有抗菌和抗病毒作用，对金黄色葡萄球菌、卡他球菌、甲型和乙型链球菌、大肠杆菌、绿脓杆菌有抑制作用，对钩端螺旋体也有杀灭作用；对流感病毒、孤儿病毒、单纯疱疹病毒、腺病毒、肠道病毒等都有明显的抑制作用。
中医认为，孩儿茶性味苦涩、凉，具有清热、化痰、止血、消食、生肌、定痛之功效，可以用来消血，治一切疮毒；疗火伤，消炎定痛；冰片性味辛苦、凉，具有通诸窍、散郁火、去翳明目、消肿止血之功效，可以用来烫、烧伤。
发明内容
为充分挖掘我国中医医学宝库，有效地克服上述烧烫伤治疗方法的缺陷，尤其是满足各类烧烫伤患者的治疗需要，本发明通过长期药物筛选和近千次临床验证，提供一种成本低廉、使用方便的治疗烧烫伤的中药酊剂及其制备方法。
本发明解决其技术问题所采用的技术方案是：
1、本发明所述的治疗烧烫伤的中药酊剂，其活性成分是由下列用量配比的中草药原料提取物制成的：
鲜虎杖根70～100，孩儿茶10～13，冰片5～7。
2、本发明所述的治疗烧烫伤中药酊剂的制备方法是：在制备时，先将鲜虎杖根洗净、切片并置于容器内，然后加入含量为足以使虎杖根切片浸没的95％医用酒精浸泡，每日翻搅一次，浸泡七日；滤取浸液，加入研磨成细末的孩儿茶，再浸泡七日；取出浸液过滤去渣，再加入冰片，熔化后装入无菌喷壶。
本发明的有益效果是：制备成本低，使用方便，适用于身体各部位、各种烧烫伤的治疗，尤其是新鲜III度和II度大面积烧烫创面的治疗，具有喷涂疼痛感轻、收敛结痂快、消炎抗感染、愈合疤痕少而小、疗程较短等显著效果。
具体实施方式
下面结合实施例对本发明作进一步地说明。
取鲜虎杖根800克，洗净晾干水份，然后切成薄片并置于洁净容器内；向容器内加入可将虎杖根切片浸没的、与虎杖根切片大约等量的95％医用酒精800克，浸泡七日，每日翻搅一次；第八日，滤取浸液除去虎杖根切片，加入研磨成细末的孩儿茶120克，再浸泡七日；第十五日，过滤去渣取出浸液，再加入冰片60克，冰片熔化后装入无菌喷壶待用。
治疗烧烫伤使用本发明时，首先清洗烧烫伤创面，用无菌棉纱吸干创面清洗消毒液体，将本发明酊剂均匀喷于创面，直至创面湿润。第一天，每小时用药1-2次，一般喷药2-5小时创面即能收敛干燥，渗出减少，第二天至第三天药痂形成后，改为每日喷药8-12次；三日后，每日喷药6-8次。使用本发明治疗I度烧烫伤，创面3-4天即可愈合；治疗浅II度烧烫伤，创面5-7天愈合；深II度烧烫伤，创面7-12天愈合；治疗临界III度或III度烧烫伤，创面12-28天愈合。
以筛选的临床治疗35例烧烫患者(其中儿童11人)为例。患者均具有特殊部位烧烫伤，其中头面颈部烧烫患者14人，头面颈部伴手前臂烧烫患者8人，面颈部伴前胸部分烧烫患者5人，头面颈上肢前胸后背均有不同面积和程度的烧烫患者5人，头面颈上肢躯干臀部及下肢散在不同程度的烧烫患者2人，患者烧烫创面均达10％以上，最大的创面达75％以上，其中浅II度、深II度、III度烧烫伤面积达5-12％。使用本发明治疗后，35例烧烫患者全部脱痂全愈，除有1例III度患者胸前和一大腿内侧留下小面积疤痕外，所有患者无一例面部留下疤痕或增生，均未再实行植皮手术，有效率达100％，治愈率达98.9％。
Claims (2)
1、治疗烧烫伤的中药酊剂，其特征在于：它的活性成分是由下列用量配比的中草药原料提取物制成的：
鲜虎杖根70～100，孩儿茶10～13，冰片5～7。
2、根据权利要求1所述的烧烫伤中药酊剂的制备方法，其特征在于：
(1)、将鲜虎杖根洗净、切片并置于容器内，加入含量为足以使虎杖根切片浸没的95％医用酒精浸泡，每日翻搅一次，浸泡七日；
(2)、滤取浸液，在滤取的浸液中加入研磨成细末的孩儿茶，再浸泡七日；
(3)、取出浸液过滤去渣，再加入冰片，熔化后装入无菌喷壶。
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| CN105456404A (zh) * | 2014-06-20 | 2016-04-06 | 杨献美 | 制备加快烧烫伤创面愈合的药物组合物外用散剂的方法 |
| CN113425792A (zh) * | 2021-08-13 | 2021-09-24 | 北京良方科技有限公司 | 一种用于治疗烫烧伤的中药外用剂及其制备方法与应用 |
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