CN117562057A - Biological-chemical synergistic insecticidal composition - Google Patents
Biological-chemical synergistic insecticidal composition Download PDFInfo
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- CN117562057A CN117562057A CN202311598082.XA CN202311598082A CN117562057A CN 117562057 A CN117562057 A CN 117562057A CN 202311598082 A CN202311598082 A CN 202311598082A CN 117562057 A CN117562057 A CN 117562057A
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- 239000000126 substance Substances 0.000 title claims abstract description 35
- 230000002195 synergetic effect Effects 0.000 title claims abstract description 27
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 25
- 239000000203 mixture Substances 0.000 title claims abstract description 25
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical group COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims abstract description 56
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims abstract description 27
- 239000005770 Eugenol Substances 0.000 claims abstract description 27
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229960002217 eugenol Drugs 0.000 claims abstract description 27
- NDHXMRFNYMNBKO-PWSUYJOCSA-N chembl2227757 Chemical group [O-][N+](=O)C([C@H]1CC[C@H](O1)N1CC2)=C1N2CC1=CC=C(Cl)N=C1 NDHXMRFNYMNBKO-PWSUYJOCSA-N 0.000 claims abstract description 14
- 239000004480 active ingredient Substances 0.000 claims abstract description 11
- 230000000975 bioactive effect Effects 0.000 claims abstract description 8
- 239000004615 ingredient Substances 0.000 claims abstract description 4
- 239000005941 Thiamethoxam Substances 0.000 claims abstract description 3
- NWWZPOKUUAIXIW-FLIBITNWSA-N thiamethoxam Chemical compound [O-][N+](=O)\N=C/1N(C)COCN\1CC1=CN=C(Cl)S1 NWWZPOKUUAIXIW-FLIBITNWSA-N 0.000 claims abstract description 3
- QAZLUNIWYYOJPC-UHFFFAOYSA-M sulfenamide Chemical compound [Cl-].COC1=C(C)C=[N+]2C3=NC4=CC=C(OC)C=C4N3SCC2=C1C QAZLUNIWYYOJPC-UHFFFAOYSA-M 0.000 claims description 7
- 239000000575 pesticide Substances 0.000 abstract description 13
- 241000607479 Yersinia pestis Species 0.000 abstract description 12
- 241000125167 Rhopalosiphum padi Species 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 8
- 206010059866 Drug resistance Diseases 0.000 abstract description 4
- 239000005783 Fluopyram Substances 0.000 abstract description 3
- 238000013329 compounding Methods 0.000 abstract description 3
- KVDJTXBXMWJJEF-UHFFFAOYSA-N fluopyram Chemical compound ClC1=CC(C(F)(F)F)=CN=C1CCNC(=O)C1=CC=CC=C1C(F)(F)F KVDJTXBXMWJJEF-UHFFFAOYSA-N 0.000 abstract description 3
- 238000011161 development Methods 0.000 abstract description 2
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- 239000003814 drug Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
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- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 description 4
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- 235000021307 Triticum Nutrition 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 239000002917 insecticide Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
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- 244000182216 Mimusops elengi Species 0.000 description 3
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- JUUFBMODXQKSTD-UHFFFAOYSA-N N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester Chemical compound N1=C(N)C(NC(=O)OCC)=CC=C1NCC1=CC=C(F)C=C1 JUUFBMODXQKSTD-UHFFFAOYSA-N 0.000 description 3
- 235000007837 Vangueria infausta Nutrition 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 3
- 229960003667 flupirtine Drugs 0.000 description 3
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- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 239000005906 Imidacloprid Substances 0.000 description 2
- 241000223201 Metarhizium Species 0.000 description 2
- 102000019027 Ryanodine Receptor Calcium Release Channel Human genes 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 description 2
- 229940056881 imidacloprid Drugs 0.000 description 2
- 230000002452 interceptive effect Effects 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 102000005962 receptors Human genes 0.000 description 2
- 108020003175 receptors Proteins 0.000 description 2
- 108091052345 ryanodine receptor (TC 1.A.3.1) family Proteins 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- SQEBMLCQNJOCBG-HVHJFMEUSA-N (5s)-3-(hydroxymethyl)-5-methoxy-4-methyl-5-[(e)-2-phenylethenyl]furan-2-one Chemical group C=1C=CC=CC=1/C=C/[C@]1(OC)OC(=O)C(CO)=C1C SQEBMLCQNJOCBG-HVHJFMEUSA-N 0.000 description 1
- WUOACPNHFRMFPN-SECBINFHSA-N (S)-(-)-alpha-terpineol Chemical compound CC1=CC[C@@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-SECBINFHSA-N 0.000 description 1
- 229940121683 Acetylcholine receptor antagonist Drugs 0.000 description 1
- 102000003922 Calcium Channels Human genes 0.000 description 1
- 108090000312 Calcium Channels Proteins 0.000 description 1
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- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 241000008892 Cnaphalocrocis patnalis Species 0.000 description 1
- 241001465977 Coccoidea Species 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 241000254171 Curculionidae Species 0.000 description 1
- 241001517923 Douglasiidae Species 0.000 description 1
- BOKTWTBRFKMMQF-UHFFFAOYSA-N FC1C(OC=C1)=O Chemical compound FC1C(OC=C1)=O BOKTWTBRFKMMQF-UHFFFAOYSA-N 0.000 description 1
- 241001466042 Fulgoromorpha Species 0.000 description 1
- 108060003393 Granulin Proteins 0.000 description 1
- 241000255967 Helicoverpa zea Species 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 206010028347 Muscle twitching Diseases 0.000 description 1
- 241001477931 Mythimna unipuncta Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000346285 Ostrinia furnacalis Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 241000500437 Plutella xylostella Species 0.000 description 1
- 241001466030 Psylloidea Species 0.000 description 1
- 241000256247 Spodoptera exigua Species 0.000 description 1
- 241000985245 Spodoptera litura Species 0.000 description 1
- 241001414989 Thysanoptera Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000000556 agonist Substances 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- OVKDFILSBMEKLT-UHFFFAOYSA-N alpha-Terpineol Natural products CC(=C)C1(O)CCC(C)=CC1 OVKDFILSBMEKLT-UHFFFAOYSA-N 0.000 description 1
- 229940088601 alpha-terpineol Drugs 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- -1 anthranilamide thiobenzamide Chemical compound 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001887 anti-feedant effect Effects 0.000 description 1
- 239000010692 aromatic oil Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 239000010624 camphor oil Substances 0.000 description 1
- 229960000411 camphor oil Drugs 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 239000010630 cinnamon oil Substances 0.000 description 1
- 239000010632 citronella oil Substances 0.000 description 1
- 239000010634 clove oil Substances 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 230000002074 deregulated effect Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000028161 membrane depolarization Effects 0.000 description 1
- 239000010413 mother solution Substances 0.000 description 1
- 239000001627 myristica fragrans houtt. fruit oil Substances 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
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- 229940075993 receptor modulator Drugs 0.000 description 1
- 238000000611 regression analysis Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P7/00—Arthropodicides
- A01P7/04—Insecticides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Insects & Arthropods (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of insecticidal compositions, and particularly relates to a bio-chemical synergistic insecticidal composition. The active ingredients of the bio-chemical synergistic insecticidal composition are compounded by bioactive ingredients and chemical active ingredients; wherein the bioactive component is eugenol; the chemical active ingredient is cycloxaprid, flupirfenidone or thiamethoxam. The invention has synergism on wheat aphids after compounding the bioactive component eugenol with chemical components of cycloxaprid, fluopyram or sulfenapyr, can improve the control effect on the wheat aphids and can reduce the use amount of pesticides. But also can delay the development of drug resistance of wheat aphids and provide support for developing novel pesticides and preventing and controlling resistant pests.
Description
Technical Field
The invention belongs to the technical field of insecticidal compositions, and particularly relates to a bio-chemical synergistic insecticidal composition.
Background
Eugenol is 4-allyl-2-methoxyphenol, and has the following structural formula:
eugenol, also known as eugenol, is an oily, fragrant compound that is widely found in aromatic oils such as clove oil, cinnamon leaf oil, camphor oil, nutmeg oil, and the like. Eugenol is widely studied in the medical field at present, and pharmacological actions mainly relate to antibacterial, sterilizing and anesthetic actions. The biological activity of four plant essential oil components on medlar cotton aphid is studied, and the biological activity of four plant essential oil components such as eugenol, alpha-terpineol, cinnamon oil, citronella oil and the like on medlar cotton aphid is found to have the strongest poisoning effect on medlar cotton aphid adult aphid.
The cycloxaprid is a cis-nitrone oxo-heterocyclic neonicotinoid insecticide independently created by the university of eastern chemical industry, can inhibit the reaction of an agonist and a nicotinic acetylcholine receptor, belongs to a nicotinic acetylcholine receptor antagonist, and is not easy to generate interactive resistance with neonicotinoid insecticides such as imidacloprid and the like. The cycloxaprid has excellent insecticidal activity against most pests of homoptera, especially rice planthoppers, aphids and whiteflies, and is also effective against lepidoptera, coleopteran and dipteran pests.
The flupirtine is an insecticide acting on a nicotinic acetylcholine receptor created by Bayer company, and the molecular structure of the flupirtine contains butenolide groups, so that the flupirtine not only inherits good prevention effect on piercing-sucking mouthparts pests possessed by other insecticide acting on the nicotinic acetylcholine receptor, but also has stronger selectivity and no interactive resistance with imidacloprid and the like. After the flupirfuranone is bonded to the receptor protein, the receptor is activated to generate biological reaction, depolarization ion flow is induced, so that target pest nerve cells are always in excited, disordered and deregulated states, and finally die due to central nervous system collapse. The flurofuranone is suitable for a plurality of crops, has wide control spectrum, and can control pests such as aphids, white flies, psyllids, leafhoppers, scale insects, beetles, leaf miners, mealy bugs, weevils, thrips and the like.
Sulfenamide is a compound of the structure of anthranilamide thiobenzamide, which is independently developed by the university of Qingdao technology. Sulfenamide is a ryanodine receptor modulator, and by combining with ryanodine receptor, calcium ion channels are opened, so that calcium ions in cells are continuously released into muscle pulp. The calcium ions combine with matrix proteins in the muscle pulp, causing the muscle to continue to shrink, and the target pests therefore exhibit symptoms such as twitching, paralysis, antifeeding, and the like, and eventually die. The sulfenamide can prevent and treat rice leaf rollers, plutella xylostella, prodenia litura, armyworms, corn borers, aphids, cotton bollworms, beet armyworms and other pests.
In the agricultural production process, the single chemical pesticide is applied for a long time, so that the insect is easy to generate drug resistance, and the control effect of the chemical pesticide is gradually reduced or even can be ineffective along with the accumulation of the drug resistance of the insect. The reasonable compounding of different insecticidal active ingredients is one of effective and convenient means for developing novel pesticides and preventing and controlling resistant pests.
Disclosure of Invention
The invention aims to provide a bio-chemical synergistic insecticidal composition which solves the problem existing in the long-term application of a single chemical pesticide.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the bio-chemical synergistic insecticidal composition is characterized in that the effective components of the bio-chemical synergistic insecticidal composition are compounded by bioactive components and chemical active components; wherein the bioactive component is eugenol; the chemical active ingredient is cycloxaprid, flupirfenidone or thiamethoxam.
The effect is better, and the mass ratio of eugenol to cycloxaprid is 1-3:15-1.
The effect is better, and the mass ratio of eugenol to flupirfuranone is 1-9:9-1.
The effect is better, and the mass ratio of eugenol to sulfenapyr is 1-10:30-1.
The invention also provides a bio-chemical synergistic pesticide which is prepared from the active ingredients of the bio-chemical synergistic pesticide composition and auxiliary ingredients.
More specifically, the mass of the active ingredients of the bio-chemical synergistic insecticidal composition accounts for 0.1-55% of the total mass of the bio-chemical synergistic insecticidal composition.
Compared with the prior art, the invention has the following beneficial effects:
the invention has synergism on wheat aphids after compounding the bioactive component eugenol with chemical components of cycloxaprid, fluopyram or sulfenapyr, can improve the control effect on the wheat aphids and can reduce the use amount of pesticides. But also can delay the development of drug resistance of wheat aphids and provide support for developing novel pesticides and preventing and controlling resistant pests.
Detailed Description
The following description of the embodiments of the present invention will be apparent from, and is intended to provide a thorough description of, the embodiments of the present invention, and not a complete description of, the embodiments of the present invention.
Examples: indoor toxicity measurement
1. Test agent
99% eugenol (Shanghai Ala Biotechnology Co., ltd.), 97% cycloxaprid (Liaoning Zhonghui Biotechnology Co., ltd.), 96% flupirfuranone (Bayer Co., ltd.), 95% sulfenamide (Zhejiang Yulong Biotechnology Co., ltd.)
Dissolving the test agent with dimethyl sulfoxide, diluting with 0.1% Tween-80 to obtain single-agent mother solution, setting multiple groups of proportions, setting 5 gradient mass concentrations of each single agent and each group of proportion mixture according to an equal ratio method, and keeping 50mL of each mass concentration liquid medicine for later use;
2. test pest
After 6 generations of wheat test field aphids are bred in a laboratory, wingless adults with consistent insect bodies and health are selected as test objects.
3. The test method comprises the following steps: ( Reference to section 6 of pesticide "NY/T1154.6-2006 pesticide indoor bioassay test guidelines: insecticidal Activity test method for soaking insects )
And (3) allowing the tested pests to enter the liquid medicine for 10s, sucking the excessive liquid medicine by using filter paper, and transferring the liquid medicine to the original feeding condition for feeding. Repeating the treatment for 4 times, immersing 25 heads of insects for each time, and setting a solution treatment only containing 0.1% of Tween-80 as a blank control; after 24 hours of treatment, investigation of the death condition of the test insects, recording of the total number and the death number of each treatment, calculation of the corrected death rate of each treatment, regression analysis of the concentration log value and the corrected death rate probability value of each treatment medicament by DPS software, calculation of LC of each treatment medicament 50 。
4. Calculation method
In the above formula: p- -mortality in units of; k- -number of dead insects; n- -total number of insects treated.
In the above formula: p (P) 1 -correct mortality in units of; p (P) t -mortality rate in units of treatment; p (P) 0 Blank mortality in%.
5. Evaluation of pharmaceutical Agents
Co-toxicity coefficients (CTC values) of the blends were calculated according to the grand cloud Pei method and the criteria were divided according to the combined effect: the co-toxicity coefficient (CTC) is more than or equal to 120, and the synergistic effect is shown; the cotoxicity coefficient (CTC) is less than or equal to 80 and shows antagonism; 80< co-toxicity coefficient (CTC) <120 shows additive effect. The results are shown in tables 1-3.
TABLE 1 toxicity of eugenol and cycloxaprid to Metarhizium Mai
As can be seen from table 1, when eugenol and cycloxaprid are compounded, the ratio of eugenol to cycloxaprid is 1-3:15-1, the co-toxicity coefficient of each compound combination to the wheat long tube aphid is more than 120, and the synergistic effect is shown.
TABLE 2 toxicity of eugenol and Fluoropifuranone to Metarhiza
As can be seen from table 2, when eugenol is compounded with flupirfuranone, the ratio of eugenol to flupirfuranone is 1-9: in 9-1, the co-toxicity coefficient of each compound combination to the wheat long tube aphid is more than 120, and the synergistic effect is shown.
TABLE 3 toxicity of eugenol and sulfenamide combination to Metarhizium Maillard
As can be seen from Table 3, when eugenol is compounded with sulfenapyr, the ratio of eugenol to sulfenamide is 1-10: within 30-1, the co-toxicity coefficient of each compound combination to the wheat long tube aphid is more than 120, and the synergistic effect is shown.
In conclusion, the invention combines the eugenol as the biological active ingredient with the cycloxaprid, the fluopyram or the sulfenapyr as the chemical ingredient to have a synergistic effect on wheat aphids, can improve the control effect on the wheat aphids, and can reduce the use amount of pesticides.
Claims (6)
1. The bio-chemical synergistic insecticidal composition is characterized in that the effective components of the bio-chemical synergistic insecticidal composition are compounded by bioactive components and chemical active components; wherein the bioactive component is eugenol; the chemical active ingredient is cycloxaprid, flupirfenidone or thiamethoxam.
2. The bio-chemical synergistic insecticidal composition according to claim 1, wherein the mass ratio of eugenol to cycloxaprid is 1-3:15-1.
3. The bio-chemical synergistic insecticidal composition according to claim 1, wherein the mass ratio of eugenol to flupirfuranone is 1-9:9-1.
4. The bio-chemical synergistic insecticidal composition according to claim 1, wherein the mass ratio of eugenol to sulfenamide is 1-10:30-1.
5. A bio-chemical synergistic insecticidal composition, characterized in that it is prepared from the active ingredients of the bio-chemical synergistic insecticidal composition according to claim 1, together with auxiliary ingredients.
6. The bio-chemical synergistic insecticidal composition as claimed in claim 5, wherein the mass of the active ingredient of the bio-chemical synergistic insecticidal composition is 0.1 to 55% of the total mass of the bio-chemical synergistic insecticidal composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202311598082.XA CN117562057A (en) | 2023-11-28 | 2023-11-28 | Biological-chemical synergistic insecticidal composition |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311598082.XA CN117562057A (en) | 2023-11-28 | 2023-11-28 | Biological-chemical synergistic insecticidal composition |
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| CN117562057A true CN117562057A (en) | 2024-02-20 |
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| CN202311598082.XA Pending CN117562057A (en) | 2023-11-28 | 2023-11-28 | Biological-chemical synergistic insecticidal composition |
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| Country | Link |
|---|---|
| CN (1) | CN117562057A (en) |
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