CN117517441A - Correction detection device for mass spectrometer - Google Patents

Correction detection device for mass spectrometer Download PDF

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Publication number
CN117517441A
CN117517441A CN202311533438.1A CN202311533438A CN117517441A CN 117517441 A CN117517441 A CN 117517441A CN 202311533438 A CN202311533438 A CN 202311533438A CN 117517441 A CN117517441 A CN 117517441A
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China
Prior art keywords
mass spectrometer
power amplification
line connector
radio frequency
board
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CN202311533438.1A
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Inventor
郝明富
刘大伟
陈昊男
吴明所
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Shanghai Inesa Analytical Instrument Co ltd
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Shanghai Inesa Analytical Instrument Co ltd
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Priority to CN202311533438.1A priority Critical patent/CN117517441A/en
Publication of CN117517441A publication Critical patent/CN117517441A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

The invention relates to a correction detection device of a mass spectrometer, comprising: the signal generator is used for connecting the input end of the radio frequency plate of the mass spectrometer to be detected and the input end of the power amplification plate of the mass spectrometer to be detected; the oscilloscope is used for connecting the output end of the radio frequency board of the mass spectrometer to be tested with the output end of the power amplification board of the mass spectrometer to be tested; the mass spectrometer quadrupole rod module is used for connecting the output end of the power amplification plate of the mass spectrometer to be tested; the current detection module is used for connecting the power amplification board of the mass spectrometer to be detected and monitoring the current value in the power amplification board of the mass spectrometer to be detected. According to the correction detection device and method for the mass spectrometer, the resonance frequency of the mass spectrometer is adjusted through the signal generator and the quadrupole rod part, the mass spectrometer is detected through the oscilloscope and the current detection module, and a user does not need to return to a factory through a whole machine when the mass spectrometer needs to be maintained, so that maintenance cost and time can be greatly reduced.

Description

Correction detection device for mass spectrometer
Technical Field
The invention relates to the technical field of analytical instruments, in particular to a correction detection device of a mass spectrometer.
Background
In the conventional four-level rod mass spectrometer, the optimal resonance frequency point of the mass spectrometer needs to be found in the factory correction detection process, and the optimal resonance frequency point is not only related to the mass spectrometer radio frequency plate, but also related to the quadrupole rod component, so that the debugging of the mass spectrometer radio frequency plate needs to be debugged on the whole machine, and a user needs to return the whole machine to the factory when the user needs to repair the mass spectrometer radio frequency plate, thereby increasing the maintenance cost and time.
Disclosure of Invention
Based on the above, it is necessary to provide a correction detection device for a mass spectrometer, so that the user does not need to return the whole machine to the factory when the radio frequency plate of the mass spectrometer needs to be maintained, and the maintenance cost and time can be greatly reduced.
A mass spectrometer calibration detection apparatus comprising:
the signal generator is used for connecting the input end of the radio frequency plate of the mass spectrometer to be detected and the input end of the power amplification plate of the mass spectrometer to be detected;
the oscilloscope is used for connecting the output end of the radio frequency board of the mass spectrometer to be tested with the output end of the power amplification board of the mass spectrometer to be tested;
the mass spectrometer quadrupole rod module is used for connecting the output end of the power amplification plate of the mass spectrometer to be tested;
the current detection module is used for connecting the power amplification board of the mass spectrometer to be detected and monitoring the current value in the power amplification board of the mass spectrometer to be detected.
In one embodiment, the mass spectrometer four-bar module includes a radio frequency coil and an adjustable capacitance connected in parallel.
In one embodiment, the adjustable capacitance is adjustable in the range of 0 to 50 picofarads.
In one embodiment, the device further comprises a first line connector, one end of the first line connector is connected with the signal generator, and the other end of the first line connector is used for being connected with an input end of a radio frequency board of the mass spectrometer to be tested.
In one embodiment, the device further comprises a second line connector, one end of the second line connector is connected with the signal generator, and the other end of the second line connector is used for being connected with the input end of the power amplification board of the mass spectrometer to be tested.
In one embodiment, the device further comprises a third line connector, one end of the third line connector is used for being connected with the output end of the power amplification board of the mass spectrometer to be detected, the other end of the third line connector is connected with the four-bar module of the mass spectrometer, and the third end of the third line connector is connected with the oscilloscope.
In one embodiment, the device further comprises a fourth line connector, one end of the fourth line connector is used for being connected with an output end of a radio frequency board of the mass spectrometer to be tested, and the other end of the fourth line connector is connected with the oscilloscope.
In one embodiment, the apparatus further comprises a portable housing, and the signal generator, oscilloscope, and mass spectrometer quadrupole module are disposed within the portable housing.
According to the correction detection device and method for the mass spectrometer, the power amplification plate of the mass spectrometer can be corrected and detected through the signal generator, the quadrupole rod module, the current detection module and the oscilloscope, and the power amplification plate of the mass spectrometer can reach the signal amplification intensity required by the instrument through adjusting the corresponding circuit on the power amplification plate of the mass spectrometer; correcting and detecting a radio frequency plate of the mass spectrometer through a signal generator and an oscilloscope, and obtaining an optimal resonant frequency by adjusting the frequency of the signal generator according to the oscilloscope; when a user maintains the mass spectrometer, the maintenance cost and time are greatly reduced, and the debugging and maintenance efficiency of the instrument is further improved.
Drawings
In order to more clearly illustrate the invention or the technical solutions of the prior art, the following description will briefly explain the drawings used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are some embodiments of the invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
Fig. 1 is a schematic structural diagram of a mass spectrometer detection and correction device of the present invention.
Reference numerals:
110. the device comprises a signal generator, 120, an oscilloscope, 130, a mass spectrometer quadrupole rod module, 131, a radio frequency coil, 132, an adjustable capacitor, 140, a current detection module, 210, a mass spectrometer power amplification board to be tested, 220, a mass spectrometer radio frequency board to be tested, 231, a first line connector, 232, a second line connector, 233, a third line connector, 234, a fourth line connector, 240 and a portable case.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It will be understood that when an element is referred to as being "mounted" or "disposed" on another element, it can be directly on the other element or intervening elements may also be present. When a component is considered to be "connected" to another component, it can be directly connected to the other component or intervening components may also be present. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and the like are used in the description of the present invention for the purpose of illustration only and do not represent the only embodiment.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present invention, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.
In the present invention, unless expressly stated or limited otherwise, a first feature "up" or "down" on a second feature may be that the first feature is in direct contact with the second feature, or that the first feature and the second feature are in indirect contact through intermedial media. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is higher in level than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely under the second feature, or simply indicating that the first feature is less level than the second feature.
Unless defined otherwise, all technical and scientific terms used in the specification of the present invention have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used in the description of the present invention includes any and all combinations of one or more of the associated listed items.
The mass spectrometer calibration detection apparatus of the present invention is described below in connection with fig. 1.
As shown in fig. 1, in one embodiment, a mass spectrometer calibration detection apparatus includes a signal generator 110, an oscilloscope 120, a mass spectrometer quadrupole module 130, a current detection module 140, a mass spectrometer power amplifier board 210 under test, and a mass spectrometer radio frequency board 220 under test.
The signal generator 110 is used for connecting the input end of the radio frequency board 220 of the mass spectrometer to be measured and the input end of the power amplification board 210 of the mass spectrometer to be measured, and preferably, the signal generator is a miniature signal generator, and the signal generator can generate a signal of 1-2 MHz.
The oscilloscope 120 is used for connecting the output end of the radio frequency board 220 of the mass spectrometer to be tested and the output end of the power amplification board 210 of the mass spectrometer to be tested, and preferably, the oscilloscope 120 is a miniature oscilloscope.
The mass spectrometer quadrupole rod module 130 is used for connecting with the output end of the mass spectrometer power amplification plate 210 to be measured.
The current detection module 140 is used for connecting the power amplification board 210 of the mass spectrometer to be detected and monitoring the current value in the power amplification board 210 of the mass spectrometer to be detected.
Specifically, when testing the power amplification board of the mass spectrometer, the signal generator 110 is connected with the power amplification board 210 of the mass spectrometer to be tested, and signals required by adjusting the frequency of the signal generator 110 are input into the power amplification board 210 of the mass spectrometer to be tested; the to-be-detected mass spectrometer power amplification plate 210 is connected with the current detection module 140, and the current detection module 140 monitors the current value on the to-be-detected mass spectrometer power amplification plate 210 in real time, so that the temperature of a core chip is prevented from being too high to cause damage to devices; the other end of the mass spectrometer power amplification plate 210 to be measured is connected with the mass spectrometer quadrupole rod module 130, and the amplified signal processed by the mass spectrometer power amplification plate 210 is applied to the mass spectrometer quadrupole rod module 130; the power amplification board 210 of the mass spectrometer to be measured is also connected with the oscilloscope 120 at one end, the signals processed and amplified by the power amplification board 210 of the mass spectrometer are synchronously output to the oscilloscope 120, whether the power amplification board 210 of the mass spectrometer reaches the signal amplification strength required by the instrument can be judged according to the voltage amplitude, the waveform and the like, and if the signal amplification strength is not reached, the corresponding circuit on the power amplification board can be adjusted.
When the mass spectrometer radio frequency board is tested, the signal generator 110 is connected with the mass spectrometer radio frequency board 220 to be tested, and signals required by adjusting the frequency of the signal generator are sent out and input into the mass spectrometer radio frequency board 220 to be tested; the rf board 220 of the mass spectrometer to be measured processes the amplified signal and outputs the signal to the oscilloscope 120, and adjusts the frequency of the signal generator 110 according to the waveform output by the oscilloscope 120 to make the signal generator reach the required waveform, and the frequency value at this time is the optimal resonance point required by the mass spectrometer.
According to the correction detection device for the mass spectrometer, the signal generator 110, the quadrupole rod module 130, the current detection module 140 and the oscilloscope 120 are used for correcting and detecting a power amplification board of the mass spectrometer, and the corresponding circuit on the power amplification board of the mass spectrometer is adjusted to enable the power amplification board of the mass spectrometer to reach the signal amplification intensity required by the instrument; correcting the detection mass spectrometer radio frequency board through the signal generator 110 and the oscilloscope 120, and obtaining the optimal resonance frequency by adjusting the frequency of the signal generator 110 according to the oscilloscope 120; when a user maintains the mass spectrometer, the maintenance cost and time are greatly reduced, and the debugging and maintenance efficiency of the instrument is further improved.
As shown in fig. 1, in one embodiment, the mass spectrometer quadrupole rod module 130 comprises a radio frequency coil 131 and an adjustable capacitor 132, the radio frequency coil 131 and the adjustable capacitor 132 being connected in parallel. The adjustable capacitance can be adjusted in the range of 0 to 50 picofarads. The amplified signal processed by the mass spectrometer power amplification plate 210 is applied to the radio frequency coil 131 and the adjustable capacitor 132, the radio frequency coil 131 is connected with the adjustable capacitor 132 in parallel, and the combined function of the radio frequency coil 131 and the adjustable capacitor 132 is equivalent to the mass spectrometer quadrupole rod module 130. Preferably, the bobbin in the radio frequency coil 131 is a low-loss ceramic bobbin.
In the correction detection device of the mass spectrometer of the embodiment, the radio frequency coil 131 and the adjustable capacitor 132 are combined into the quadrupole rod module 130 of the mass spectrometer, and the optimal resonance frequency point is found through the quadrupole rod module 130.
As shown in fig. 1, in one embodiment, the mass spectrometer calibration detection device includes a first line connector 231, a second line connector 232, a third line connector 233, and a fourth line connector 234. A first line connector 231, one end of which is connected with the signal generator 110, and the other end of which is connected with the input end of the radio frequency plate 220 of the mass spectrometer to be measured; a second line connector 232, one end of which is connected with the signal generator 110, and the other end of which is connected with the input end of the mass spectrometer power amplification board 210 to be measured; one end of the third line connector 233 is connected with the output end of the to-be-detected mass spectrometer power amplification plate 210, the other end of the third line connector 233 is connected with the mass spectrometer quadrupole rod module 130, and the third end of the third line connector is connected with the oscilloscope 120; a fourth line connector 234 has one end connected to the output of the rf plate 220 of the mass spectrometer under test and the other end connected to the oscilloscope 120.
Specifically, when detecting the power amplification board of the mass spectrometer, the connection between the signal generator 110 and the first line connector 231 is disconnected, the connection between the oscilloscope 120 and the fourth line connector 234 is disconnected, the signal generator 110 is connected with the second line connector 232, the second line connector 232 is connected with the power amplification board 210 of the mass spectrometer to be detected, the power amplification board 210 of the mass spectrometer to be detected is connected with the third line connector 233, and the third line connector 233 is connected with the quadrupole module 130 of the mass spectrometer and the oscilloscope 120; when the mass spectrometer radio frequency board is detected, the connection between the signal generator 110 and the second line connector 232 is disconnected, the connection between the oscilloscope 120 and the third line connector 233 is disconnected, the signal generator 110 is connected with the first line connector 231, the first line connector 231 is connected with the mass spectrometer radio frequency board 220 to be detected, the mass spectrometer radio frequency board 220 to be detected is connected with the fourth line connector 234, and the fourth line connector 234 is connected with the oscilloscope 120.
According to the mass spectrometer correction detection device, through the use of the line connector, the connection relation between the line connector and each module can be freely changed, connection and closing between lines can be more conveniently adjusted, and the mass spectrometer correction detection device is more convenient and quick to use, and improves detection efficiency.
As shown in fig. 1, in one embodiment, the mass spectrometer calibration detection apparatus includes a portable housing 240, and the signal generator 110, oscilloscope 120, and mass spectrometer quadrupole module 130 are disposed within the portable housing 240. The first line connector 231, the second line connector 232, the third line connector 233, and the fourth line connector 234 are disposed on the portable chassis panel.
The correction and detection device for the mass spectrometer of the embodiment is characterized in that the signal generator 110, the mass spectrometer quadrupole rod module 130 and the oscilloscope 120 are arranged in the portable case 240, so that the correction and detection device is convenient to carry during use, and the overhaul efficiency is improved; the circuit connector is arranged on the portable case panel, so that the circuit connector is conveniently connected with the internal module and the external module of the portable case 240, disconnection and connection of the circuit are facilitated, and the use requirements of multiple scenes are met.
In the above-mentioned calibration monitoring device for a mass spectrometer, when a test mass spectrometer power amplification board is selected, the connection between the signal generator 110 and the first line connector 231 is disconnected, the signal generator 110 is connected with the second line connector 232, the second line connector 232 is connected with the mass spectrometer power amplification board 210 to be tested, the signal generator 110 sends out a signal, and the mass spectrometer power amplification board 210 processes the signal; the to-be-detected mass spectrometer power amplification plate 210 is connected with a third line connector 233, one end of the third line connector 233 is connected with the mass spectrometer quadrupole rod module 130, the other end of the third line connector 233 is connected with the oscilloscope 120, the fourth line connector 234 is disconnected with the oscilloscope 120, signals processed by the mass spectrometer power amplification plate 210 are output to the third line connector 233, the third line connector 233 transmits the signals to the mass spectrometer quadrupole rod module 130 and the oscilloscope 120, whether the mass spectrometer power amplification plate reaches the signal amplification intensity required by an instrument or not is judged according to the voltage amplitude, the waveform and the like displayed by the oscilloscope 120, and if the voltage amplitude and the waveform and the like do not reach the signal amplification intensity, the corresponding circuit on the power amplification plate can be adjusted to adjust the signal amplification intensity; the current detection module 140 is further connected to the to-be-detected mass spectrometer power amplification board 210, and the current detection module 140 can monitor the current value in the mass spectrometer power amplification board 210 in real time, so that the temperature of the core chip is ensured not to be too high, and the device is prevented from being damaged. When the test mass spectrometer radio frequency board is selected, the connection between the signal generator 110 and the second line connector 232 is disconnected, the signal generator 110 outputs a signal to the second line connector 232, and the second line connector 232 outputs the signal to the to-be-tested mass spectrometer radio frequency board 220 for processing; the oscilloscope 120 is disconnected from the third line connector 233 and connected with the fourth line connector 234, the mass spectrometer radio frequency board 220 processes the amplified signal and outputs the signal to the fourth line connector 234, the signal is transmitted to the oscilloscope 120 through the fourth line connector 234, and the frequency of the signal generator is adjusted according to the waveform output by the oscilloscope 120 to reach the required waveform, and the frequency value at this time is the optimal resonance point required by the mass spectrometer.
The power amplification plate of the mass spectrometer is corrected to the signal amplification intensity required by the instrument through detection and correction of the power amplification plate of the mass spectrometer and the radio frequency plate of the mass spectrometer, and the optimal frequency resonance point is obtained through adjustment of the signal generator when the radio frequency plate of the mass spectrometer is detected, so that the efficiency of factory debugging and after-sale overhaul of the instrument is improved, and the maintenance cost is reduced; meanwhile, the signal waveform analysis is facilitated, the condition of the power amplification board is judged, and the debugging and overhauling efficiency of the instrument is further improved.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims (8)

1. A mass spectrometer calibration detection apparatus comprising:
the signal generator is used for connecting the input end of the radio frequency plate of the mass spectrometer to be detected and the input end of the power amplification plate of the mass spectrometer to be detected;
the oscilloscope is used for connecting the output end of the radio frequency board of the mass spectrometer to be tested with the output end of the power amplification board of the mass spectrometer to be tested;
the mass spectrometer quadrupole rod module is used for connecting the output end of the power amplification plate of the mass spectrometer to be tested;
the current detection module is used for connecting the power amplification board of the mass spectrometer to be detected and monitoring the current value in the power amplification board of the mass spectrometer to be detected.
2. The mass spectrometer calibration detection device of claim 1, wherein the mass spectrometer four-bar module comprises a radio frequency coil and an adjustable capacitance, the radio frequency coil and the adjustable capacitance being connected in parallel.
3. The mass spectrometer calibration detection apparatus of claim 2, wherein the adjustable capacitance is adjustable in a range of 0 to 50 picofarads.
4. The mass spectrometer calibration detection device of claim 1, further comprising a first line connector having one end connected to the signal generator and another end for connection to an input of a radio frequency plate of a mass spectrometer to be measured.
5. The apparatus of claim 1, further comprising a second line connector having one end connected to the signal generator and another end for connection to an input of a power amplifier board of the mass spectrometer to be measured.
6. The device of claim 1, further comprising a third line connector, wherein one end of the third line connector is used to connect with an output end of a power amplification board of the mass spectrometer to be measured, the other end of the third line connector is connected with the four-bar module of the mass spectrometer, and the third end of the third line connector is connected with the oscilloscope.
7. The apparatus of claim 1, further comprising a fourth line connector having one end for connection to an output of a radio frequency plate of a mass spectrometer to be measured and another end for connection to the oscilloscope.
8. The mass spectrometer calibration detection device of claim 1, further comprising a portable housing, wherein the signal generator, oscilloscope, and mass spectrometer quadrupole module are disposed within the portable housing.
CN202311533438.1A 2023-11-16 2023-11-16 Correction detection device for mass spectrometer Pending CN117517441A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202311533438.1A CN117517441A (en) 2023-11-16 2023-11-16 Correction detection device for mass spectrometer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202311533438.1A CN117517441A (en) 2023-11-16 2023-11-16 Correction detection device for mass spectrometer

Publications (1)

Publication Number Publication Date
CN117517441A true CN117517441A (en) 2024-02-06

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202311533438.1A Pending CN117517441A (en) 2023-11-16 2023-11-16 Correction detection device for mass spectrometer

Country Status (1)

Country Link
CN (1) CN117517441A (en)

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