CN1174765C - Composite Chinese medicine for treating venereal disease and dermatosis and its prepn. - Google Patents
Composite Chinese medicine for treating venereal disease and dermatosis and its prepn. Download PDFInfo
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- CN1174765C CN1174765C CNB01120558XA CN01120558A CN1174765C CN 1174765 C CN1174765 C CN 1174765C CN B01120558X A CNB01120558X A CN B01120558XA CN 01120558 A CN01120558 A CN 01120558A CN 1174765 C CN1174765 C CN 1174765C
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Abstract
The present invention discloses a traditional Chinese medicine composition for treating venereal diseases and skin diseases, and a preparation technology thereof. The traditional Chinese medicine is prepared from 40 to 60g of phellodendron bark, 10 to 30g of ginger, 10 to 30g of flavescent sophora root, 10 to 30g of common cnidium fruit, 10 to 30g of flos lonicerae, 10 to 30g of herba violae, 5 to 10g of sanguis draconis, 5 to 10g of myrrh, 10 to 30g of aloe, 5 to 10g of dried alum, 5 to 10g of sal ammoniac, 30 to 50g of dandelion and 5 to 15g of borax. The traditional Chinese medicine is pulverized and is loaded in a reactor, and then the traditional Chinese medicine is heated, circulated and extracted; after an extracting solution is evaporated and concentrated and is dissolved with solvent oil, oil and fat in medicine liquid are removed, and residue is dissolved with water; after being filtered, supernatant liquid is dried, and the dried substances are pulverized again to obtain supernatant spare medicine powder; the solvent oil is rectified in a rectifying tower to obtain medicine oil; the supernatant medicine powder is dissolved in water, and trolamine is added in the supernatant medicine powder; the medicine oil, paraffin, stearic acid and propanol are added in the medicine powder to be mixed and dissolved; then ethylparaben is added in the medicine powder; and the mixture is evenly mixed into paste.
Description
Invention field
The present invention relates to Chinese medicine composition and preparation technology thereof, particularly have heat clearing away and draw out pus by applying a plaster to the affected part, holder skin ulcer eliminating stagnation, killing parasites for relieving itching, dampness removing astriction can be treated various sexually transmitted disease (STD)s, dermopathic Chinese medicine composition and preparation technology thereof.
Background technology
Prior art, treatment sexually transmitted disease (STD), dermopathic Chinese medicine and preparation technology thereof are mainly as follows:
The multiple sexually transmitted disease (STD) of a kind of treatment, gynopathic medicine are disclosed among the CN93110820, the prescription that it is characterized in that described Chinese medicine preparation includes Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sophorae Flavescentis, Herba Senecionis Scandentis, Flos Lonicerae, weight proportion relation in the prescription between the various pure natural plant pharmacopoeias is Rhizoma Coptidis 6-18 gram, Cortex Phellodendri 6-24 gram, Radix Et Rhizoma Rhei 9-30 gram, Radix Sophorae Flavescentis 9-30 gram, Herba Senecionis Scandentis 15-30 gram, Flos Lonicerae 15-30 gram.
CN1106682 discloses a kind of Chinese medicine preparation that is used for the treatment of female vagina and common venereal diseases prevention, it is characterized in that it comprises the weight percent component is 2～20% Indigo Naturalis, 2～20% Flos Lonicerae, 2～20% Rhizoma Polygoni Cuspidati, 2～20% Fructus Cnidii, 2～20% the Radix Stemonae, 2～20% Rhizoma Smilacis Glabrae, 2～20% Cortex Hibisci, 2～20% Cortex Dictamni, 2～20% Radix Et Rhizoma Rhei, 2～20% Aloe, 0～15% Oleum Bulbus Allii, 0～15% Pericarpium Zanthoxyli, 0～15% dried Alumen, 0～10% Borneolum Syntheticum, dried Alumen will be removed in the above-mentioned weight percent component, beyond Borneolum Syntheticum and the Oleum Bulbus Allii all the other ten simply Chinese medicine clean, chopping, insert in the apparatus,Soxhlet's, alcohol reflux with 95% 3 times, merge gained ethanol liquid, in gained ethanol liquid, add suitable quantity of water, jolting, leave standstill, remove precipitated impurities, above-mentioned roguing process repeats three times, be recycled to the gained solution decompression dried, get former medicine extractum, again with the dried Alumen in the above-mentioned weight percent component, Borneolum Syntheticum and Oleum Bulbus Allii add, weigh, volume ratio is 1: 30 a ratio adding distilled water by weight, dilution, dissolving makes.Have the trichomonal vaginitis of killing, Candida albicans, gonococcus, chlamydia, the braking treponema pallidum destroys drug effects such as HIV (human immunodeficiency virus) surface antigen.Therefore, evident in efficacy to female vagina and common venereal diseases.
Disclose a kind of Chinese medicine for the treatment of dermatosis, sexually transmitted disease (STD) among the CN1228970, it is characterized in that: it is the medicament of being made by the following weight proportion raw material: 10～15 parts of companies of 10～15 parts of Rhizoma Chuanxiongs of 10～15 parts of Poria of 20～25 parts of Radixs Astragali of 5～15 parts of Radix Sophorae Flavescentiss of Radix Codonopsis call 10～15 parts of 20～25 parts of anti-15～20 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of 15～20 parts of Radixs Angelicae Dahuricae of 15～20 parts of Radix Platycodoniss of 15～20 parts of Radix Peucedanis of 10～15 parts of Rhizoma Atractylodis of rich 15～20 parts of Radix Paeoniae Rubra of 15～20 parts of Radix Isatidiss of 15～20 portions of Folium Isatidiss of 15～20 portions of Herba Violaes of 20～25 parts of Herba Taraxacis of 15～20 parts of Flos Loniceraes of 15～20 parts of pollen together.
With in recent years, along with growth in the living standard, dermatosis, sexually transmitted disease (STD) have gradually the trend that rises in various places, seek effective medicine, treat various dermatosiss, sexually transmitted disease (STD) is very significant.
The content of invention
The objective of the invention is to disclose a kind of treatment sexually transmitted disease (STD), dermopathic Chinese medicine composition, this Chinese medicine composition has heat clearing away draws out pus by applying a plaster to the affected part, and holder skin ulcer eliminating stagnation, killing parasites for relieving itching, dampness removing astriction can be treated various sexually transmitted disease (STD)s.
Another purpose of another purpose of the present invention is to disclose the preparation technology of above-mentioned treatment sexually transmitted disease (STD), dermatosis Chinese medicine composition.
To achieve these goals, the technical solution used in the present invention is: a kind of treatment sexually transmitted disease (STD), dermopathic traditional Chinese herb medicine, and it consists of:
Cortex Phellodendri 40-60g, Rhizoma Zingiberis Recens 10-30g, Radix Sophorae Flavescentis 10-30g, Fructus Cnidii 10-30g, Flos Lonicerae 10-30g, Herba Violae 10-30g, Sanguis Draxonis 5-10g, Myrrha 5-10g, Aloe 10-30g, dried Alumen 5-10g, Sal Ammoniacus 5-10g, Herba Taraxaci 20-50g, Borax 5-15g.
The preparation method of Chinese medicine composition of the present invention is: above-mentioned side's medicated powder is broken, pack in the reactor, be extracted into extracting liquid colourless with the ethanol circulation of heating, extracting solution evaporation and concentration to the basic Ex-all of ethanol is taken out, after the dissolving of Semen sojae atricolor solvent naphtha, medicinal liquid medium oil seborrheic alopecia is gone out, residue is with the water dissolution of 1 to 0.5 ratio, the precipitation that stirs 4 hours, get supernatant, filter with filter paper or filter cloth, filtrate enters the vacuum drying box oven dry, and it is standby that taking-up oven dry thing obtains supernatant medicated powder with the pulverizing mill pulverizing, and sinking medical material liquid can be done oral medicine and use; Medicine oil in the Semen sojae atricolor solvent naphtha obtains medicine oil with rectifying column rectification.
Adopt above-mentioned preparation method, the extracts active ingredients in the Chinese medicine can be come out, as little medicine alkali, phellodendrine, hurdle alkali, bitterness obacunone, the Cortex Phellodendri fat in the Cortex Phellodendri; Matrine in the Radix Sophorae Flavescentis, oxymatrine, methyl passeris montani saturati flower alkali, Anagyrine; Left-handed pinene in the Fructus Cnidii, isoamyl Borneolum Syntheticum fat, Radix Angelicae Dahuricae element, Fructus Citri Sarcodactylis dodge fat, different pimpinellin, osthole; Lonicerin in the Flos Lonicerae, Radix Ophiopogonis element, loganin; Multiple glycoside in the Herba Violae, flavonoid; The red pigment of the red resin in the Sanguis Draxonis, crystallization shape, dracorhodin, dracorubin; Poponax resin in the Myrrha, fat phenol, acetic acid, different fragrant fat; Barbaloin in the Aloe, aloe-emodin, new aloin, aloe; After extracting, above-mentioned main component all is extracted out, is absorbed by the body easily.
Wherein Fa Ming dried Alumen is a blue vitriol; The stone Sal Ammoniacus promotes the dermal osmosis effect of medicine.
Chinese medicine composition of the present invention can be made oral capsule, oral liquid, orally looses, oral medicine pill, external suppository, external-applied ointment or external wash liquid.
The prescription of described external-applied ointment and preparation method are: get 7 kilograms in supernatant medicated powder, 3 kilograms of medicine oil, 40 kilograms of propanol, 14 kilograms of triethanolamine, 15 kilograms of stearic acid, 1 kilogram in paraffin, 10 kilograms in water; Medicated powder in the water dissolving of heating, again to wherein adding triethanolamine, is heated to 80 degree, medicine oil, paraffin, stearic acid, propanol are added to stir dissolve, add ethyl hydroxybenzoate 10 grams again, stir to becoming paste.
Wherein said Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Herba Taraxaci, Herba Violae and Rhizoma Polygoni Cuspidati have the effect of heat-clearing and toxic substances removing; Aloe, Fructus Cnidii, Alumen and Radix Sophorae Flavescentis have the killing parasites for relieving itching effect; Rhizoma Zingiberis Recens, Hedyotidis Diffusae have to regulate separates the human body function of exempting from service; Sanguis Draxonis, Myrrha, Borax, stone Sal Ammoniacus have dissipating blood stasis and treat skin ulcer, saturating skin eliminating stagnation effect; Chinese medicine composition of the present invention is by the synergism of above-mentioned Chinese medicine, can heat clearing away draw out pus by applying a plaster to the affected part, holder skin ulcer eliminating stagnation, killing parasites for relieving itching, dampness removing astriction, be used for the treatment of various sexually transmitted disease (STD)s, dermatosis, as sexually transmitted disease (STD) and treating for skin disease such as herpes simplex, chancroid, colpitis mycotica, trichomonal vaginitis, cervical erosion, eczema, acne, acne rosacea, beriberi.
The specific embodiment
Embodiment 1
Cortex Phellodendri 40g, Rhizoma Zingiberis Recens 10g, Radix Sophorae Flavescentis 30g, Fructus Cnidii 30g, Flos Lonicerae 10g, Herba Violae 10g, Sanguis Draxonis 5g, Myrrha 10g, Aloe 30g, dried Alumen 5g, Sal Ammoniacus 10g, Herba Taraxaci 30g, Borax 15g.
Above-mentioned side's medicated powder is broken, pack in the reactor, be extracted into extracting liquid colourless with the circulation of heating of 500ml ethanol, extracting solution evaporation and concentration to the basic Ex-all of ethanol taken out, after the dissolving of 500ml Semen sojae atricolor solvent naphtha, medicinal liquid medium oil seborrheic alopecia is gone out, residue is with the water dissolution of 1 to 0.5 ratio, and the precipitation that stirs 4 hours is got supernatant, filtered with filter paper or filter cloth, filtrate enters the vacuum drying box oven dry, and it is standby that taking-up oven dry thing obtains supernatant medicated powder with the pulverizing mill pulverizing; Medicine oil in the Semen sojae atricolor solvent naphtha obtains medicine oil with rectifying column rectification.
Get 7 kilograms in supernatant medicated powder, 3 kilograms of medicine oil, 40 kilograms of propanol, 14 kilograms of triethanolamine, 15 kilograms of stearic acid, 1 kilogram in paraffin, 10 kilograms in water; Medicated powder in the water dissolving of heating, again to wherein adding triethanolamine, is heated to 80 degree, medicine oil, paraffin, stearic acid, propanol are added to stir dissolve, add ethyl hydroxybenzoate 10 grams again, stir to becoming paste, packing.
Embodiment 2
Cortex Phellodendri 50g, Rhizoma Zingiberis Recens 20g, Radix Sophorae Flavescentis 20g, Fructus Cnidii 20g, Flos Lonicerae 20g, Herba Violae 20g, Sanguis Draxonis 8g, Myrrha 7g, Aloe 20g, dried Alumen 7g, Sal Ammoniacus 8g, Herba Taraxaci 20g, Borax 10g.
Adopt the method preparation of embodiment 1.
Embodiment 3
Cortex Phellodendri 60g; Rhizoma Zingiberis Recens 30g; Radix Sophorae Flavescentis 10g; Fructus Cnidii 10g; Flos Lonicerae 30g; Herba Violae 30g; Sanguis Draxonis 5g; Myrrha 5g; Aloe 10g; Dried Alumen 10g; Sal Ammoniacus 5g, Herba Taraxaci 20g, Borax 10g, Herba Taraxaci 50g, Borax 5.
Adopt the method preparation of embodiment 1.
Therapeutic effect of the present invention is as follows:
| Ointment of the present invention is to following routine disease total effective rate | ||||||
| Disease | The man | The woman | Effective number | Effective percentage | The healing number | Cure rate |
| Herpes simplex | 100 people | Do not have | 92 people | 92％ | 86 people | 86％ |
| Chancroid | 36 people | Do not have | 28 people | 77.8％ | 21 people | 58.3％ |
| Colpitis mycotica | 88 people | 12 people | 98 people | 98％ | 98 people | 98％ |
| Trichomonal vaginitis | Do not have | 100 people | 98 people | 98％ | 98 people | 98％ |
| Cervical erosion | Do not have | 100 people | 97 people | 97％1 | 95 people | 95％ |
| Eczema | 63 people | 37 people | 100 people | 100％ | 100 people | 100％ |
| Acne | 42 people | 58 people | 100 people | 100％ | 100 people | 100％ |
| Acne rosacea | 76 people | 24 people | 100 people | 100％ | 100 people | 100％ |
| Beriberi | 90 people | 10 people | 100 people | 100％ | 100 people | 100％ |
| Carbuncle | 34 people | 9 people | 38 people | 88.4％ | 38 people | 88.4％ |
Claims (4)
1. treat sexually transmitted disease (STD), dermopathic Chinese medicine composition for one kind, it is characterized in that it is to be made by the following weight proportion raw material: Cortex Phellodendri 40-60g, Rhizoma Zingiberis Recens 10-30g, Radix Sophorae Flavescentis 10-30g, Fructus Cnidii 10-30g, Flos Lonicerae 10-30g, Herba Violae 10-30g, Sanguis Draxonis 5-10g, Myrrha 5-10g, Aloe 10-30g, dried Alumen 5-10g, Sal Ammoniacus 5-10g, Herba Taraxaci 20-50g, Borax 5-15g.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by the following weight proportion raw material: Cortex Phellodendri 50g, Rhizoma Zingiberis Recens 20g, Radix Sophorae Flavescentis 20g, Fructus Cnidii 20g, Flos Lonicerae 20g, Herba Violae 20g, Sanguis Draxonis 8g, Myrrha 7g, Aloe 20g, dried Alumen 7g, Sal Ammoniacus 8g, Herba Taraxaci 20g, Borax 10g.
3. treat sexually transmitted disease (STD) for one kind, the preparation method of dermopathic Chinese medicine composition, it is characterized in that Cortex Phellodendri 40-60g, Rhizoma Zingiberis Recens 10-30g, Radix Sophorae Flavescentis 10-30g, Fructus Cnidii 10-30g, Flos Lonicerae 10-30g, Herba Violae 10-30g, Sanguis Draxonis 5-10g, Myrrha 5-10g, Aloe 10-30g, dried Alumen 5-10g, Sal Ammoniacus 5-10g, Herba Taraxaci 20-50g, Borax 5-15g pulverizes, pack in the reactor, be extracted into extracting liquid colourless with the ethanol circulation of heating, extracting solution evaporation and concentration to the basic Ex-all of ethanol is taken out, after the dissolving of Semen sojae atricolor solvent naphtha, medicinal liquid medium oil seborrheic alopecia is gone out, residue is with the water dissolution of 1 to 0.5 ratio, the precipitation that stirs 4 hours, get supernatant liquid filtering, the filtrate oven dry, it is standby that the pulverizing of taking-up oven dry thing obtains supernatant medicated powder; Medicine oil in the Semen sojae atricolor solvent naphtha obtains medicine oil with rectifying column rectification.
4. preparation method according to claim 3, it is characterized in that Cortex Phellodendri 40-60g, Rhizoma Zingiberis Recens 10-30g, Radix Sophorae Flavescentis 10-30g, Fructus Cnidii 10-30g, Flos Lonicerae 10-30g, Herba Violae 10-30g, Sanguis Draxonis 5-10g, Myrrha 5-10g, Aloe 10-30g, dried Alumen 5-10g, Sal Ammoniacus 5-10g, Herba Taraxaci 20-50g, Borax 5-15g pulverizes, pack in the reactor, be extracted into extracting liquid colourless with the ethanol circulation of heating, extracting solution evaporation and concentration to the basic Ex-all of ethanol is taken out, after the dissolving of Semen sojae atricolor solvent naphtha, medicinal liquid medium oil seborrheic alopecia is gone out, the water dissolution of the ratio of residue 1 to 0.5, the precipitation that stirs 4 hours, get supernatant liquid filtering, the filtrate oven dry, it is standby that the pulverizing of taking-up oven dry thing obtains supernatant medicated powder; Medicine oil in the Semen sojae atricolor solvent naphtha obtains medicine oil with rectifying column rectification; Get 7 kilograms in supernatant medicated powder, 3 kilograms of medicine oil, 40 kilograms of propanol, 14 kilograms of triethanolamine, 15 kilograms of stearic acid, 1 kilogram in paraffin, 10 kilograms in water; Medicated powder in the water dissolving of heating, again to wherein adding triethanolamine, is heated to 80 degree, medicine oil, paraffin, stearic acid, propanol are added to stir dissolve, add ethyl hydroxybenzoate 10 grams again, stir and tremble evenly to becoming paste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01120558XA CN1174765C (en) | 2001-07-23 | 2001-07-23 | Composite Chinese medicine for treating venereal disease and dermatosis and its prepn. |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01120558XA CN1174765C (en) | 2001-07-23 | 2001-07-23 | Composite Chinese medicine for treating venereal disease and dermatosis and its prepn. |
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| CN1389231A CN1389231A (en) | 2003-01-08 |
| CN1174765C true CN1174765C (en) | 2004-11-10 |
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| CNB01120558XA Expired - Fee Related CN1174765C (en) | 2001-07-23 | 2001-07-23 | Composite Chinese medicine for treating venereal disease and dermatosis and its prepn. |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100406040C (en) * | 2005-10-28 | 2008-07-30 | 郑州羚锐制药有限公司 | Lotion for treating vulva itching |
| CN101780172B (en) * | 2010-03-29 | 2012-08-29 | 贵阳德昌祥药业有限公司 | Bacteriostatic washing liquor with high bacteriostatic action and method for preparing same |
| CN102793832B (en) * | 2012-09-07 | 2014-08-20 | 江苏仁寿药业有限公司 | Novel micro-ecological modulator and preparation method thereof |
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