CN117442696A - Traditional Chinese medicine and external application for treating infantile anorexia and preparation method thereof - Google Patents
Traditional Chinese medicine and external application for treating infantile anorexia and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating infantile anorexia, an external application patch and a preparation method thereof. The traditional Chinese medicine is prepared by combining clove, amomum villosum, stir-fried bighead atractylodes rhizome, stir-fried rhizoma atractylodis, costustoot, rhizoma curcumae, radish seed and borneol with corresponding auxiliary materials. In the formula, the clove is used as a monarch, so that the traditional Chinese medicine can warm middle energizer and yang and also can tonify fire to warm soil; the three Chinese herbal medicines of fructus amomi and rhizoma atractylodis macrocephalae are ministerial medicines for strengthening spleen and simultaneously can dispel dampness, assist monarch medicines for warming spleen yang and promoting diuresis and clearing heat; the banksia rose and the radish seed and the zedoary have the effects of strengthening spleen and promoting digestion, and are used as adjuvants, and are capable of warming qi and promoting digestion, and reducing stomach and resolving food stagnation; borneol has the effects of inducing resuscitation, refreshing mind, clearing heat and relieving pain, and can guide all the medicines to pass through the heart and abdomen, and dispel all orifices. The medicines in the whole formula are matched to achieve good effects.
Description
Technical Field
The invention belongs to the technical field of medicines, and in particular relates to a traditional Chinese medicine and external application patch for treating infantile anorexia and a preparation method thereof.
Background
Child anorexia is a common spleen and stomach disease of children, and is a common child disease characterized by long-term aversion to food and reduced food intake. If anorexia is not improved for a long time, a series of symptoms such as retarded growth and development, low immunity, repeated infection and the like of children can be caused, and the anorexia becomes a high risk factor for the occurrence and development of other diseases and seriously affects the growth and development of children.
The traditional Chinese medicine has long been aware of infantile anorexia, and it is considered that infantile anorexia is often caused by congenital deficiency and weakness of spleen and stomach; improper feeding, injuring spleen and stomach; emotional disorder, liver qi obstruction, spleen obstruction and stomach obstruction; other diseases damage the spleen, spleen failing to transport and stomach qi failing to control sodium. The traditional Chinese medicine diagnosis and treatment standard refers to the diagnosis and treatment guideline of pediatric common diseases in traditional Chinese medicine, and the infantile anorexia can be divided into spleen and stomach disharmony syndrome, spleen and stomach damp-heat syndrome, spleen and stomach qi deficiency syndrome, spleen and stomach yin deficiency syndrome and liver hyperactivity and spleen deficiency syndrome, and the traditional Chinese medicine treatment of infantile anorexia is focused on the whole, and the diagnosis and treatment follow the basic principle of' spleen strengthening is absent and tonifying is carried out. So as to avoid the problems of delayed and insufficient grain essence intake, no qi and blood generation, slow growth and development of children, systemic emaciation and even influence on the intelligence development of children.
In the treatment of infantile anorexia, the traditional Chinese medicine is taken orally, so that the invention provides a traditional Chinese medicine for treating infantile anorexia by external use. Although some external plaster for treating the spleen and stomach system diseases of children exist at present, for example, external plaster such as compound clove appetizing plaster, clove navel plaster, gastrointestinal powder and the like are also available. However, the above medicine composition is mainly aimed at diseases of spleen and stomach system which occur in short term. Compared with the traditional Chinese medicine, the traditional Chinese medicine is especially aimed at children with poor appetite and anorexia for a long time, and has the characteristics of definite curative effect, no side effect, excellent curative effect and the like. The traditional Chinese medicine plays the curative effect advantage of the traditional Chinese medicine, and has important significance for preventing and treating infantile anorexia and maintaining the health of children.
Disclosure of Invention
The invention aims at achieving the purposes of strengthening spleen and stomach, activating blood and regulating qi through the dual functions of the medicine and the acupoint. In addition, aiming at the characteristic of difficult oral administration of the medicine for children, the medicine is specially prepared as an acupoint plaster which is easy to be accepted by children and is applied to corresponding acupoints. Therefore, the invention provides a traditional Chinese medicine external patch for treating infantile anorexia and a preparation process thereof, which is a self-fitting prescription in our hospital, adopts a pure traditional Chinese medicine prescription, obtains good curative effect by clinical observation for many years, has definite curative effect for treating infantile anorexia, has no side effect and has good compliance for infants.
Aiming at the characteristics of inappetence, anorexia and picky children frequently accompanied with qi stagnation and blood stasis, the invention specially adds the curcuma zedoary for activating blood circulation to dissipate blood stasis; the stir-fried radish seed, costustoot, fructus amomi and other products for strengthening spleen and regulating qi, strengthening spleen and stomach, and regulating qi and removing blood stasis simultaneously achieve the aim of treating both symptoms and root causes.
The efficacy of each medicine in the invention is as follows:
clove-warm middle-jiao to reduce adverse flow of qi, promote qi circulation to relieve pain, refresh mind and induce resuscitation;
fructus Amomi-has effects of eliminating dampness, stimulating appetite, warming spleen, relieving diarrhea, regulating qi-flowing, and preventing miscarriage;
roasted atractylodes macrocephala-strengthening spleen, tonifying qi, drying dampness, promoting diuresis, stopping sweating and preventing abortion;
stir-fried rhizoma atractylodis-drying dampness and strengthening spleen, dispelling wind and cold and improving eyesight;
radix aucklandiae, having effects of warming spleen and stomach, activating qi-flowing, relieving pain, invigorating spleen, resolving food stagnation;
zedoary, which breaks blood, moves qi, eliminates food retention and relieves pain;
radish seed, which has the functions of promoting digestion, removing distention and reducing qi and phlegm;
borneol, which has the functions of inducing resuscitation and refreshing mind, clearing heat and relieving pain and is aromatic.
The method takes the clove as the monarch, the clove is pungent in taste and warm in nature, and the functions of warming the middle energizer and lowering adverse qi, tonifying the kidney and supporting yang are achieved, and the medicine is provided with clouds in the formula: the Chinese medicinal composition has the effects of tonifying liver, nourishing the life gate, warming the stomach and removing middle-warmer cold, and can warm the middle-warmer and yang, tonify fire and warm soil, and one medicine can be used for treating diseases successively, so that the Chinese medicinal composition is a monarch for treating diseases from the aspect of successively; deficiency-cold in middle energizer, spleen deficiency failing to transport, transforming and removing weakness, body fluids failing to ascend and clear, and water dampness stopping accumulation is the basis for treating the root cause, and spleen-strengthening and dampness-dispelling herbs are also needed. Fructus Amomi, fructus Xanthii and Atractylodis rhizoma are ministerial drugs. The three medicines can invigorate spleen, dispel dampness, promote the warming of spleen yang, promote diuresis and clear. Restoring the normal function of spleen ascending and clearing. Spleen and stomach dysfunction, spleen failing to ascend and clear, and stomach qi failing to descend must be seen. If stomach qi is not decreased, the diet is stopped in the stomach and intestine, and food stagnation is caused. The three medicines of costustoot and radish seed and zedoary are used as adjuvants for strengthening spleen and promoting digestion. Banksia rose and radish seed, semen Raphani, with the actions of warming and activating qi and resolving food stagnation, can lower stomach and resolve food retention. The zedoary has the taste Xin Xinglie of the Chinese herbal medicine "Fu Zhu Wei", which is specially used for attacking qi and blood, mainly breaking food retention and eliminating hard mass, removing food retention in stomach and intestine, and simultaneously can promote qi and blood circulation and smooth qi and blood circulation to restore normal ascending and descending of spleen and stomach. Borneol is pungent, bitter and slightly cold. It has the actions of inducing resuscitation and refreshing mind, and clearing heat and relieving pain. "Tang Ben Cao" cloud: pathogenic qi in the heart and abdomen and wind-damp accumulation are all pungent and dispersed, which can lead the herbs to pass through the heart and abdomen and disperse the orifices, so it is the guiding herb. The whole formula has the effects of warming spleen and stomach, tonifying kidney, supporting yang, resolving dampness, ascending clear, strengthening spleen, removing food retention, promoting qi circulation and relieving pain. Move qi and remove dampness without hurting the healthy energy, strengthen the body and deeply nourish yin and yang.
The aim of the invention is achieved by the following technical scheme.
A traditional Chinese medicine for treating infantile anorexia is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 1-20 parts of clove, 1-20 parts of fructus amomi, 1-20 parts of fried bighead atractylodes rhizome, 1-20 parts of fried rhizoma atractylodis, 1-20 parts of costustoot, 1-20 parts of rhizoma curcumae, 1-20 parts of radish seed and 0.5-10 parts of borneol.
And (3) combining auxiliary materials: azone, edible vinegar, sodium benzoate, and air-permeable adhesive plaster. Grinding the traditional Chinese medicine raw materials into powder, uniformly mixing according to a proportion, wherein the dosage of auxiliary materials is as follows: every 1 part of mixed traditional Chinese medicine powder uses 0.5 part of azone, a proper amount of edible vinegar and 0.05 part of sodium benzoate.
The application method comprises the following steps: the preparation is applied topically to navel. The method comprises the following steps: the pill is put into navel (shenque acupoint), and is applied with breathable adhesive for 4-8 hr/day, and 7 days is a treatment course.
Notice that: 1. it is an external medicine, and is prohibited from being taken orally. 2. The application part is not suitable for use such as skin injury, itching, red swelling, etc., for example, the disease condition is not relieved after the medicine is applied, and the doctor is required to seek in time. 3. It is an external adjuvant drug, for example, after a course of treatment, the symptoms cannot be relieved, and please seek medical attention in time. 4. Please place in places where children are not easy to reach, and the children use the medicine under the constant supervision of parents. 5. It should be used with cautions for allergic patients.
The traditional Chinese medicine for treating infantile anorexia is preferably prepared from the following raw materials: 5-10 parts of clove, 3-6 parts of fructus amomi, 1-5 parts of stir-fried bighead atractylodes rhizome, 1-5 parts of stir-fried rhizoma atractylodis, 3-6 parts of costustoot, 1-5 parts of rhizoma curcumae, 1-5 parts of radish seed and 0.5-5 parts of borneol.
Further comprises flos Caryophylli 1 part, fructus Amomi 1 part, parched Atractylodis rhizoma 1 part, parched rhizoma Atractylodis 1 part, radix aucklandiae 1 part, curcumae rhizoma 1 part, raphani semen 1 part, and Borneolum Syntheticum 0.5 part.
The preparation method of the traditional Chinese medicine for treating infantile anorexia comprises the following steps: grinding Guan Yaowu into powder, mixing, adding azone, edible vinegar, sodium benzoate, and air-permeable adhesive, and making into topical patch.
According to the external treatment principle of the internal diseases in the traditional Chinese medicine, the external patch with quick response, high curative effect, no side effect and high acceptance is provided. The selected medicine has no toxic or side effect, the active ingredients of the medicine can be released rapidly and absorbed by skin rapidly, and the medicine can directly reach focus to play a role in treatment, and has quick and durable effect compared with the conventional oral administration, and adverse reactions of stomach, liver and kidney are not caused. The navel is applied externally, which belongs to the main point of health care of human body. The product can treat both principal and secondary aspect of disease, and can radically regulate and improve gastrointestinal tract function while strengthening spleen, regulating qi and stimulating appetite.
To illustrate the therapeutic effect of the present invention, the following experiments were performed. The treatment group adopts the scheme of the invention, the comparative example 1 is a commercially available compound clove appetizing paste (the medicinal ingredients comprise clove, rhizoma atractylodis, bighead atractylodes rhizome, cardamom, fructus amomi, elecampane and borneol), the comparative example 2 is a scheme of replacing radish seed with chicken's gizzard-skin in the formula of the invention, and the comparative example 3 is a scheme of replacing curcuma zedoary with rhizoma sparganii in the formula of the invention. 120 cases of children who are treated within 3 years of the clinic of the children in the hospital and conform to the anorexia of the children, the diagnosis of the children in each group in terms of abdominal distension, abdominal pain, borborygmus, nausea and vomiting, greasy mouth and bitter taste and inappetence 6 before treatment is not significantly different, and the children in each group are 30 cases in 4 groups according to the random digital meter method, wherein the 4 groups are respectively: treatment groups, comparative examples 1-3. The first one is the improvement result of each group in terms of abdominal distension, abdominal pain, borborygmus, nausea and vomiting, greasy mouth and bitter taste and inappetence after 2 weeks of treatment.
Table one:
as is clear from the first table, the treatment group and the comparative examples 1 to 3 had an improving effect on infantile anorexia in abdominal distension, abdominal pain, borborygmus, nausea and vomiting, bitter taste in mouth, inappetence and the like. The results show that the treatment group showed superior effects on each indication compared to the comparative examples 1-3. Comparative examples 2 and 3 the adjuvant in the formulation was screened, and after the comparison of the curative effect, the adjuvant with better index in all aspects was selected as the scheme of zedoary and radish seed, and the scheme of the invention was developed.
Typical cases:
child males, 6 years old.
Initial consultation complaints: less food intake is accompanied with fatigue and weakness for more than 2 months. The infant starts to suffer from bad appetite, anorexia, tiredness and debilitation, greasy mouth and bitter taste, abdominal distension and borborygmus after eating, nausea symptoms, abdominal pain, normal urine and stool. Checking: bilateral tonsils are not swollen, heart and lung check bodies are not abnormal, abdomen is not pressed and painful, rebound pain is not caused, percussion drum sound is obvious, borygmus is caused, complexion is pale and white, tongue is pale and fat, tongue coating is white and greasy, and pulse is smooth.
Diagnosis: anorexia.
The treatment method comprises the following steps: warming spleen and stomach, invigorating kidney, supporting yang, eliminating dampness, ascending clear, strengthening spleen, resolving food stagnation, promoting qi circulation, and relieving pain.
Prescription: 9 parts of clove, 6 parts of fructus amomi, 5 parts of stir-fried bighead atractylodes rhizome, 5 parts of stir-fried rhizoma atractylodis, 5 parts of elecampane, 3 parts of rhizoma curcumae, 3 parts of radish seed, 1 part of borneol and the like.
Two diagnoses: the infant has obviously improved stomach, bitter taste in mouth, improved abdominal distention, slightly dripping stool, no nausea symptoms, pale tongue and thin white coating.
Prescription: 9 parts of clove, 5 parts of fructus amomi, 5 parts of stir-fried bighead atractylodes rhizome, 5 parts of stir-fried rhizoma atractylodis, 1 part of elecampane, 1 part of rhizoma curcumae, 1 part of radish seed and 1 part of borneol, and the navel is applied externally for one week.
Three diagnoses: abdominal distension, abdominal pain, and borborygmus are known to be manifested as constipation and appetite. The curative effect is consolidated by coordinating with daily diet.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
Example 1
A traditional Chinese medicine for treating infantile anorexia comprises the following traditional Chinese medicine raw materials in parts by weight: 1-20 parts of clove, 1-20 parts of fructus amomi, 1-20 parts of fried bighead atractylodes rhizome, 1-20 parts of fried rhizoma atractylodis, 1-20 parts of costustoot, 1-20 parts of rhizoma curcumae, 1-20 parts of radish seed and 0.5-10 parts of borneol.
Example 2
A traditional Chinese medicine for treating infantile anorexia comprises the following traditional Chinese medicine raw materials in parts by weight: 5-10 parts of clove, 3-6 parts of fructus amomi, 1-5 parts of stir-fried bighead atractylodes rhizome, 1-5 parts of stir-fried rhizoma atractylodis, 3-6 parts of costustoot, 1-5 parts of rhizoma curcumae, 1-5 parts of radish seed and 0.5-5 parts of borneol.
Example 3
A traditional Chinese medicine for treating infantile anorexia comprises the following traditional Chinese medicine raw materials in parts by weight: further comprises flos Caryophylli 1 part, fructus Amomi 1 part, parched Atractylodis rhizoma 1 part, parched rhizoma Atractylodis 1 part, radix aucklandiae 1 part, curcumae rhizoma 1 part, raphani semen 1 part, and Borneolum Syntheticum 0.5 part.
Claims (5)
1. A traditional Chinese medicine for treating infantile anorexia comprises the following traditional Chinese medicine raw materials in parts by weight: 1-20 parts of clove, 1-20 parts of fructus amomi, 1-20 parts of fried bighead atractylodes rhizome, 1-20 parts of fried rhizoma atractylodis, 1-20 parts of costustoot, 1-20 parts of rhizoma curcumae, 1-20 parts of radish seed and 0.5-10 parts of borneol.
2. The traditional Chinese medicine for treating infantile anorexia according to claim 1, which comprises the following traditional Chinese medicine raw materials in parts by weight: 5-10 parts of clove, 3-6 parts of fructus amomi, 1-5 parts of stir-fried bighead atractylodes rhizome, 1-5 parts of stir-fried rhizoma atractylodis, 3-6 parts of costustoot, 1-5 parts of rhizoma curcumae, 1-5 parts of radish seed and 0.5-5 parts of borneol.
3. The traditional Chinese medicine for treating infantile anorexia according to claim 2, which comprises the following traditional Chinese medicine raw materials in parts by weight: further comprises flos Caryophylli 1 part, fructus Amomi 1 part, parched Atractylodis rhizoma 1 part, parched rhizoma Atractylodis 1 part, radix aucklandiae 1 part, curcumae rhizoma 1 part, raphani semen 1 part, and Borneolum Syntheticum 0.5 part.
4. A traditional Chinese medicine for treating infantile anorexia according to any one of claims 1-3, which is prepared by combining the traditional Chinese medicine raw materials with auxiliary materials of azone, edible vinegar and sodium benzoate, and pasting the traditional Chinese medicine raw materials with breathable adhesive to prepare an external patch.
5. The method for preparing the external application agent according to claim 4, wherein the raw materials of the traditional Chinese medicine are ground into powder, and the powder is mixed according to the proportion, and the auxiliary materials are used in the following amounts: every 1 part of the mixed traditional Chinese medicine powder is uniformly mixed with 0.5 part of azone and 0.05 part of sodium benzoate by a proper amount of edible vinegar, and the mixture is applied to a breathable adhesive tape to prepare an external application agent.
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