CN117442394B - Linkage type vertebral body prosthesis - Google Patents
Linkage type vertebral body prosthesis Download PDFInfo
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- CN117442394B CN117442394B CN202311789368.6A CN202311789368A CN117442394B CN 117442394 B CN117442394 B CN 117442394B CN 202311789368 A CN202311789368 A CN 202311789368A CN 117442394 B CN117442394 B CN 117442394B
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- 238000000034 method Methods 0.000 claims abstract description 53
- 230000008569 process Effects 0.000 claims abstract description 51
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- 230000033001 locomotion Effects 0.000 claims abstract description 13
- 210000000988 bone and bone Anatomy 0.000 claims description 9
- 239000000654 additive Substances 0.000 claims description 6
- 230000000996 additive effect Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 210000005036 nerve Anatomy 0.000 claims description 6
- 230000037182 bone density Effects 0.000 claims description 3
- 238000005516 engineering process Methods 0.000 abstract description 2
- 230000004927 fusion Effects 0.000 description 6
- 230000009471 action Effects 0.000 description 4
- 238000005452 bending Methods 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 210000001503 joint Anatomy 0.000 description 3
- 208000008035 Back Pain Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 208000003618 Intervertebral Disc Displacement Diseases 0.000 description 1
- 206010061246 Intervertebral disc degeneration Diseases 0.000 description 1
- 206010050296 Intervertebral disc protrusion Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 208000031264 Nerve root compression Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 206010037779 Radiculopathy Diseases 0.000 description 1
- 206010041549 Spinal cord compression Diseases 0.000 description 1
- 208000019804 backache Diseases 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 208000018180 degenerative disc disease Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000011900 installation process Methods 0.000 description 1
- 208000021600 intervertebral disc degenerative disease Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 206010039722 scoliosis Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
Abstract
The invention provides a linkage type vertebral body prosthesis, which comprises: upper and lower vertebral plates; the transmission device is a hemispherical body, and spherical teeth are arranged on the surface of the hemispherical body; the driving device is provided with two conical teeth which are meshed with spherical teeth on the transmission device; the driving device further comprises a driving rod, one end of the driving rod is fixedly connected with the conical teeth, a first fixed block is arranged at the other end of the driving rod, and a ball socket is arranged on the driving rod; one end of the telescopic device is fixed on the upper conical plate, and the other end of the telescopic device is fixed on the ball socket on the driving rod; the second fixing block is connected with the spinous process on the spine in a fitting way; the spinous process fixing device is fixed on a driving rod of the driving device at one end and fixed on the second fixing block at the other end; a housing. The technical scheme of the application effectively solves the problems that the vertebral prosthesis in the related technology cannot simulate the attribute of human body movement and is low in stability.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to the field of implantation of vertebral prosthesis.
Background
A vertebral body prosthesis is a medical device commonly used after discectomy to replace the excised disc to restore the height and stability of the intervertebral space. The use of the vertebral body prosthesis mainly aims at intervertebral disc degeneration, intervertebral disc bulge or intervertebral disc protrusion and other intervertebral disc related diseases. These problems may lead to nerve root compression, spinal cord compression, or cause symptoms such as lumbago and backache. The design of the vertebral body prosthesis aims to mimic the natural disc structure, provide stable support, and allow a degree of motion. Such devices are typically made of biocompatible materials such as metal alloys, polyethylene or other similar materials.
The prosthetic operation of the vertebral body is generally considered a viable treatment option, particularly for those patients in need of discectomy. However, there are also some risks and limitations to the operation of the vertebral prosthesis, such as surgical complications, prosthetic displacement or failure, etc. The decision whether to use the vertebral prosthesis should be evaluated and decided by the doctor according to the specific condition of the patient.
The prior vertebral body prostheses are presented in a fusion device mode, the intervertebral fusion device is placed between adjacent vertebral bodies to play a role in fixation, although the pathological changes between the vertebral bodies can be solved, the pathological changes are prevented from being further worsened, the motion attribute between two adjacent intervertebral discs is sacrificed, and meanwhile, the clinical intervertebral fusion device is fixed only by fusion on the surface contacted with bones due to lack of a fixing device, so that the intervertebral fusion device is easy to loosen.
Disclosure of Invention
The invention aims to provide a coordinated type vertebral body prosthesis so as to solve the problems that the vertebral body prosthesis cannot simulate the attribute of human body movement and is low in stability.
In order to solve the problems, the invention provides a coordinated type vertebral body prosthesis, which specifically comprises: the upper cone plate and the lower cone plate are respectively fixed on the lower surface and the upper surface of the adjacent vertebral bodies of the vertebra; the transmission device is a hemispherical body, one end of the plane of the hemispherical body is fixed on the upper conical plate, and spherical teeth are arranged on the surface of the hemispherical body; the driving device is provided with two conical teeth which are symmetrically arranged left and right and meshed with spherical teeth on the transmission device; the driving device further comprises a driving rod, one end of the driving rod is fixedly connected with the conical teeth, a first fixed block is arranged at the other end of the driving rod, and a ball socket is further arranged on the driving rod; one end of the telescopic device is fixed on the upper conical plate, and the other end of the telescopic device is fixed on the ball socket on the driving rod; the second fixing block is connected with the spinous process on the spine in a fitting way; the spinous process fixing device is two symmetrical annular columns, one end of each annular column is fixed on a driving rod of the driving device, and the other end of each annular column is fixed on a second fixing block; and a shell, wherein one end of the shell is fixedly connected with the lower cone plate, and a gap is arranged between the other end of the shell and the upper cone plate.
Further, when the driving device and the transmission device are positioned at the initial position, the transmission device is meshed with the conical teeth of the driving devices at two sides, and when the transmission device is offset by a certain angle, the transmission device is separated from the conical teeth at one side and is continuously meshed with the conical teeth at the other side.
Further, the telescopic device further includes: one end of the sleeve is fixed on the upper conical plate, and a cuboid clamping groove is formed in the surface of the sleeve; the limiting ball is arranged in the ball socket on the driving rod; one end of the elastic component is abutted with the bottom of the sleeve, and the other end of the elastic component is fixedly connected with the limit ball; and the limiting column is matched with the clamping groove and used for limiting the movement distance of the limiting ball.
Further, the diameter of the limiting ball is larger than the caliber of the ball socket on the driving rod, and the limiting ball is limited in the ball socket.
Further, the second fixing block includes: the rotating block is embedded in the second fixed block and can rotate along the horizontal direction; the spinous process groove is arranged in the second fixing block and is tightly connected with the spinous process on the spine.
Further, one end of the spinous process fixing device is provided with a first fixing groove which is connected with a first fixing block on the driving rod and used for controlling the driving device to rotate.
Further, the annular cylinder of the spinous process fixation device is positioned outside the spinal central nerve for protection of the central nerve.
Further, the spinous process groove can be personalized by way of additive manufacturing for conforming the spinous process to the spinous process groove.
Further, the parts of the upper cone plate and the lower cone plate, which are contacted with the vertebral column, are provided with bone trabecular structures.
Further, the bone trabecular structure can be personalized by means of additive manufacturing for matching bone density and structural features of different patients.
By applying the technical scheme of the invention, the upper cone plate and the lower cone plate are respectively fixed on the lower surface and the upper surface of the adjacent vertebral bodies of the vertebra; the transmission device is a hemispherical body, one end of the plane of the hemispherical body is fixed on the upper conical plate, and spherical teeth are arranged on the surface of the hemispherical body; the driving device is provided with two conical teeth which are symmetrically arranged left and right and meshed with spherical teeth on the transmission device; the driving device further comprises a driving rod, one end of the driving rod is fixedly connected with the conical teeth, a first fixed block is arranged at the other end of the driving rod, and a ball socket is further arranged on the driving rod; one end of the telescopic device is fixed on the upper conical plate, and the other end of the telescopic device is fixed on the ball socket on the driving rod; the second fixing block is in fit connection with the spinous process on the spine; the spinous process fixing device is two annular columns which are bilaterally symmetrical, one end of each annular column is fixed on a driving rod of the driving device, and the other end of each annular column is fixed on a second fixing block; one end of the shell is fixedly connected with the lower cone plate, and a gap is arranged between the other end of the shell and the upper cone plate. Through the arrangement, the upper vertebral plate and the lower vertebral plate are fixed between adjacent vertebral bodies, the driving devices and the transmission devices on two sides are meshed with each other, the driving devices are connected with the spinous process fixing devices, the second fixing blocks are fixed on spinous processes, in the moving process, the spinous processes move to drive the driving devices to rotate, and then the transmission devices are driven to rotate, so that the upper vertebral plate moves along with the vertebral joints, and in the left-right bending and stretching process, the spinous process fixing devices drive the driving devices, and the driving devices drive the telescopic devices to swing left and right of the vertebral joints. After the vertebral prosthesis is implanted into a human body, the upper vertebral joint and the lower vertebral joint can move relatively under the action of the spinous process, so that normal use of a patient is facilitated, postoperative recovery is facilitated, the movement range of the transmission device can be limited by the limiting block, and the transmission device is prevented from falling off in the movement process. Therefore, the technical scheme effectively solves the technical problems of lack of motion attribute and low stability of the intervertebral disc in the related technology.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention. In the drawings:
FIG. 1 shows a cross-sectional view of a linked vertebral body prosthesis;
fig. 2 shows a front view of the drive device;
FIG. 3 shows a front triaxial view of the transmission;
FIG. 4 shows a front view of the telescoping device;
fig. 5 shows an elevation view of the spinous process fixation device;
FIG. 6 shows a schematic view of the assembly of a linked cone prosthesis;
wherein the above figures include the following reference numerals: 10. a driving device; 101. conical teeth; 102. a ball socket; 103. a driving rod; 104. a first fixed block; 20. a transmission device; 201. spherical teeth; 30. a telescoping device; 301. a sleeve; 302. a clamping groove; 303. an elastic member; 304. a limit column; 305. a limit ball; 40. a spinous process fixation device; 401. a first fixing groove; 50. a second fixed block; 501. a rotating block; 502. spinous process groove; 60. an upper lamina; 70. a lower lamina; 80. a housing.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. The following description of at least one exemplary embodiment is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments in accordance with the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present invention unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but should be considered part of the specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.
As shown in fig. 1-6, a linked vertebral body prosthesis comprising: an upper lamina 60, a lower lamina 70, secured to the inferior and superior surfaces of adjacent vertebral bodies of the spine, respectively; the transmission device 20 is a hemisphere, one end of the plane of the hemisphere is fixed on the upper conical plate, and spherical teeth 201 are arranged on the surface of the hemisphere; the driving device 10 is provided with two conical teeth 101 which are symmetrically arranged left and right and meshed with spherical teeth on the transmission device; the driving device further comprises a driving rod 103, one end of the driving rod is fixedly connected with the conical teeth, a first fixing block 104 is arranged at the other end of the driving rod, and a ball socket 102 is further arranged on the driving rod; one end of the expansion device 30 is fixed on the upper conical plate, and the other end is fixed on the ball socket on the driving rod; the second fixing block 50 is connected with the spinous process on the spine in a fitting way; the spinous process fixing device 40 is two symmetrical annular columns, one end of each annular column is fixed on a driving rod of the driving device, and the other end of each annular column is fixed on a second fixing block 50; one end of the housing 80 is fixedly connected to the lower lamina and a gap is provided between the other end and the upper lamina.
As shown in fig. 1, when the driving device and the transmission device are positioned at the initial position, the transmission device is meshed with the conical teeth of the driving devices at two sides, and when the transmission device is offset by a certain angle, the transmission device is separated from the conical teeth at one side and is continuously meshed with the conical teeth at the other side. Thus, the movement of the intervertebral joint is realized, for example, when the upper cone plate swings leftwards, the upper cone plate is extruded leftwards under the action of the intervertebral, so that the left side of the spherical teeth of the transmission device is meshed with the conical teeth of the driving device, meanwhile, the left side telescopic device above the driving device is contracted to move downwards under the action of the spinous process, and the right side telescopic device is stretched to move upwards, so that the left-right swing and front-back flexion and extension of the spinal joint are realized.
Preferably, the spherical teeth of the transmission device and the gears of the driving device are kept to be meshed in a certain angle, and the normal scoliosis angle is about 10 degrees, so that the left-right swinging angle of the transmission device is controlled to be within 10 degrees, the spherical teeth of the transmission device can be arranged to be wedge-shaped or round in a range exceeding 10 degrees, or different gear intervals of the transmission device can be arranged, and the situation that the gears on the driving device are blocked under the condition of overlarge swing and floating is prevented.
As shown in fig. 4, the telescopic device further includes: a sleeve 301, one end of which is fixed on the upper conical plate, and the surface of which is provided with a cuboid clamping groove 302; a limit ball 305 placed in the ball socket on the driving rod; an elastic component 303, one end of which is abutted with the bottom of the sleeve, and the other end of which is fixedly connected with the limit ball; the limiting column 304 is matched with the clamping groove and used for limiting the movement distance of the limiting ball. The diameter of the limiting ball is larger than the caliber of the ball socket on the driving rod, and the limiting ball is used for limiting the limiting ball in the ball socket. That is, in the process of bending and stretching the spine forwards and backwards, the telescopic device moves circularly along the ball socket track on the driving rod, and the movement track of the telescopic device and the movement track of the upper vertebral plate are concentric circles, so that the telescopic device can always keep synchronous with the upper vertebral plate in the process of bending and stretching forwards and backwards and leftwards and rightwards.
As shown in fig. 5, the second fixing block 50 includes: the rotating block 501 is embedded in the second fixed block and can rotate along the horizontal direction; the spinous process groove 502 is disposed in the second fixing block and is tightly connected with the spinous process on the spine. The spinous process grooves can be personalized by way of additive manufacturing for conforming the spinous process to the spinous process groove. I.e., the spinal column swings side to side, the spinous processes will rotate with each other within the rotating block. One end of the spinous process fixing device 40 is provided with a first fixing groove 401 connected with the first fixing block on the driving rod for controlling the driving device to rotate. The annular column body of the spinous process fixing device is arranged on the outer side of the spinal central nerve and used for protecting the central nerve.
As shown in FIG. 6, the installation schematic diagram of the invention is shown, the prosthesis implanted into the vertebral body and the spinous process fixing device are separately designed through the split type design, so that the operation difficulty can be reduced to a great extent, in the installation process, firstly, the driving device transmission device is partially implanted between the intervertebral discs, then the spinous process fixing devices at two sides, namely the annular cylinder body, are installed, finally, the second fixing block is sleeved, then the second fixing block is fixedly connected with the annular cylinder body on the spinous process fixing device, and under the action of the first fixing block, the annular cylinder body of the spinous process fixing device can drive the driving device to rotate. The device has the advantages that after all the devices are installed, the position of the vertebral prosthesis can be adjusted by adjusting the annular column body of the spinous process fixing device, so that the angle of the vertebral prosthesis meets the requirement of preoperative planning.
Meanwhile, the parts of the upper cone plate and the lower cone plate, which are contacted with the spine, are provided with bone trabecula structures. The bone trabecular structure can be personalized by means of additive manufacturing for matching bone density and structural characteristics of different patients. On the one hand, the bone trabecular structure can generate better fusion effect with a human body after implantation, and on the other hand, in the implantation process, the bone trabecular structure has good fixing effect due to the rough surface, so that the annular column body of the spinous process fixing device is convenient to install.
In the description of the present invention, it should be understood that the azimuth or positional relationships indicated by the azimuth terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal", and "top, bottom", etc., are generally based on the azimuth or positional relationships shown in the drawings, merely to facilitate description of the present invention and simplify the description, and these azimuth terms do not indicate and imply that the apparatus or elements referred to must have a specific azimuth or be constructed and operated in a specific azimuth, and thus should not be construed as limiting the scope of protection of the present invention; the orientation word "inner and outer" refers to inner and outer relative to the contour of the respective component itself.
Spatially relative terms, such as "above … …," "above … …," "upper surface at … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations of "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
In addition, the terms "first", "second", etc. are used to define the components, and are only for convenience of distinguishing the corresponding components, and the terms have no special meaning unless otherwise stated, and therefore should not be construed as limiting the scope of the present invention.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. A linked vertebral body prosthesis comprising:
the upper cone plate and the lower cone plate are respectively fixed on the lower surface and the upper surface of the adjacent vertebral bodies of the vertebra;
the transmission device is a hemispherical body, one end of the plane of the hemispherical body is fixed on the upper conical plate, and spherical teeth are arranged on the surface of the hemispherical body;
the driving device is provided with two conical teeth which are arranged symmetrically left and right and meshed with spherical teeth on the transmission device; the driving device further comprises a driving rod, one end of the driving rod is fixedly connected with the conical teeth, a first fixed block is arranged at the other end of the driving rod, and a ball socket is further arranged on the driving rod;
one end of the telescopic device is fixed on the upper conical plate, and the other end of the telescopic device is fixed on the ball socket on the driving rod;
a second fixed block, the second fixed block comprising: the rotating block is embedded in the second fixed block and can rotate along the horizontal direction; the spinous process groove is arranged in the second fixing block and is tightly connected with the spinous process on the spine;
the spinous process fixing device is two symmetrical annular columns, one end of each annular column is provided with a first fixing groove, the first fixing groove is connected with a first fixing block on the driving rod and used for controlling the driving device to rotate, and the other end of each annular column is fixed on a second fixing block;
the shell, the one end and the lower vertebral plate fixed connection of shell, be provided with the gap between the other end and the last conical plate.
2. The linked vertebral prosthesis of claim 1 wherein the drive means and the transmission means are in the initial position wherein the transmission means intermeshes with the tapered teeth of the drive means on both sides and disengages from the tapered teeth on one side and continues to intermesh with the tapered teeth on the other side when the transmission means is biased at an angle.
3. The linked vertebral body prosthesis of claim 1, wherein the telescoping device further comprises:
one end of the sleeve is fixed on the upper conical plate, and a cuboid clamping groove is formed in the surface of the sleeve;
the limiting ball is placed in the ball socket on the driving rod;
one end of the elastic component is abutted with the bottom of the sleeve, and the other end of the elastic component is fixedly connected with the limit ball;
and the limiting column is matched with the clamping groove and used for limiting the movement distance of the limiting ball.
4. A linked vertebral body prosthesis according to claim 3, wherein the stop ball has a diameter greater than the bore of the socket on the drive rod for limiting the stop ball within the socket.
5. The linked vertebral body prosthesis of claim 1, wherein the annular cylinder of the spinous process fixation device is disposed outside of the spinal central nerve for protection of the central nerve.
6. The linked vertebral body prosthesis of claim 1, wherein the spinous process groove is personalized by way of additive manufacturing for conforming the spinous process to the spinous process groove.
7. The linked vertebral body prosthesis of claim 1, wherein the portions of the upper and lower lamina in contact with the spinal column are provided with bone trabecular structures.
8. The linked vertebral body prosthesis of claim 7, wherein the bone trabecular structure is personalized by way of additive manufacturing for matching bone density and structural characteristics of different patients.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311789368.6A CN117442394B (en) | 2023-12-25 | 2023-12-25 | Linkage type vertebral body prosthesis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311789368.6A CN117442394B (en) | 2023-12-25 | 2023-12-25 | Linkage type vertebral body prosthesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN117442394A CN117442394A (en) | 2024-01-26 |
| CN117442394B true CN117442394B (en) | 2024-03-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311789368.6A Active CN117442394B (en) | 2023-12-25 | 2023-12-25 | Linkage type vertebral body prosthesis |
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| Country | Link |
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| CN (1) | CN117442394B (en) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2870719B1 (en) * | 2004-05-27 | 2007-09-21 | Spine Next Sa | SPINAL ARTHROPLASTY SYSTEM |
| US20060036324A1 (en) * | 2004-08-03 | 2006-02-16 | Dan Sachs | Adjustable spinal implant device and method |
| US7854752B2 (en) * | 2004-08-09 | 2010-12-21 | Theken Spine, Llc | System and method for dynamic skeletal stabilization |
| US20080183209A1 (en) * | 2005-09-23 | 2008-07-31 | Spinal Kinetics, Inc. | Spinal Stabilization Device |
| US7867279B2 (en) * | 2006-01-23 | 2011-01-11 | Depuy Spine, Inc. | Intervertebral disc prosthesis |
| US9095380B2 (en) * | 2009-03-31 | 2015-08-04 | Hamid R. Mir | Spinous process cross-link |
| US9622792B2 (en) * | 2009-04-29 | 2017-04-18 | Nuvasive Specialized Orthopedics, Inc. | Interspinous process device and method |
| US11931269B2 (en) * | 2017-07-10 | 2024-03-19 | Xtant Medical, Inc. | Delivery systems for interspinous, interlaminar stabilization devices and methods of use |
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| CN117442394A (en) | 2024-01-26 |
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