CN117400338B - Processing equipment and method for preparing colloidal gold test paper by three-dimensional cell epitope - Google Patents
Processing equipment and method for preparing colloidal gold test paper by three-dimensional cell epitope Download PDFInfo
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- CN117400338B CN117400338B CN202311388589.2A CN202311388589A CN117400338B CN 117400338 B CN117400338 B CN 117400338B CN 202311388589 A CN202311388589 A CN 202311388589A CN 117400338 B CN117400338 B CN 117400338B
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- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 title claims abstract description 126
- 238000012545 processing Methods 0.000 title claims abstract description 105
- 238000012360 testing method Methods 0.000 title claims abstract description 72
- 238000000034 method Methods 0.000 title claims description 8
- 239000010931 gold Substances 0.000 claims abstract description 55
- 229910052737 gold Inorganic materials 0.000 claims abstract description 55
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 46
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 241000252254 Catostomidae Species 0.000 claims description 5
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 238000003825 pressing Methods 0.000 abstract description 4
- 239000002699 waste material Substances 0.000 abstract description 3
- 239000000463 material Substances 0.000 abstract description 2
- 238000003672 processing method Methods 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 description 10
- 230000002745 absorbent Effects 0.000 description 10
- 238000010586 diagram Methods 0.000 description 6
- 239000002184 metal Substances 0.000 description 6
- 229910052751 metal Inorganic materials 0.000 description 6
- 239000011265 semifinished product Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000010030 laminating Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000012491 analyte Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000009614 chemical analysis method Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/01—Means for holding or positioning work
- B26D7/02—Means for holding or positioning work with clamping means
- B26D7/025—Means for holding or positioning work with clamping means acting upon planar surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B5/00—Cleaning by methods involving the use of air flow or gas flow
- B08B5/02—Cleaning by the force of jets, e.g. blowing-out cavities
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/06—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/27—Means for performing other operations combined with cutting
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses processing equipment and a processing method for preparing colloidal gold test paper by using three-dimensional cell epitopes, and belongs to the technical field of processing of colloidal gold test paper. Processing equipment for preparing colloidal gold test paper by three-dimensional cell epitopes comprises a processing table and further comprises: the mounting shaft is arranged on the processing table and is provided with raw materials for preparing the colloidal gold test paper; the limiting clamp plate is arranged on the processing table, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate; the sucker is arranged on the limiting clamping plate; the rotating shaft is rotationally connected to the processing table, and a pressing roller is arranged on the rotating shaft; the correcting blocks are circumferentially distributed on the rotating shaft; a cutting unit provided on the processing table; the colloidal gold test paper comprises a bottom plate, an NC film, water absorbing paper, a sample pad and a gold mark pad; according to the invention, the water absorbing paper, the gold mark pad and the sample pad can be accurately adhered according to the length of the bottom plate, so that the waste of materials is avoided.
Description
Technical Field
The invention relates to the technical field of colloidal gold test paper processing, in particular to processing equipment for preparing colloidal gold test paper by using three-dimensional cell epitopes.
Background
The paper chip is a carrier for three-dimensional cell culture, can be used for three-dimensional cell epitope preparation, and can be designed into multiple functions, wherein one of the functions is used for chemical analysis. The colloidal gold test paper may be integrated into the paper chip as part of the paper chip. Through the micro-channel structure of the paper chip, the sample can flow in the micro-channel structure, and through contacting with the colloidal gold test paper, the analyte can react with the chemical reagent on the test paper to generate color change. Such color changes may be measured and analyzed by optical methods or other detection means to obtain the desired result; therefore, the paper chip and the colloidal gold test paper can be combined to provide a quick, low-cost and portable chemical analysis method, and have wide application prospects in the fields of biomedicine, environmental monitoring, food safety and the like.
When the colloidal gold test paper is prepared, NC film pasting, scribing (C, T line), metal spraying and other processes are needed to be carried out successively, after drying and the like, the water absorbing paper, the metal mark pad and the sample pad are pasted on the semi-finished product of the colloidal gold test paper, at present, gaps can appear between the water absorbing paper, the metal mark pad and the sample pad basically by manpower, the pasting is not tight, in order to enable the water absorbing paper, the metal mark pad and the sample pad to be covered on the semi-finished product of the colloidal gold test paper as much as possible, the lengths of the pasted water absorbing paper, the metal mark pad and the sample pad are far longer than those of the semi-finished product of the colloidal gold test paper, and the water absorbing paper, the metal mark pad and the sample pad which exceed the semi-finished product of the colloidal gold test paper are needed to be cut off after pasting is finished, and unnecessary waste is caused.
Disclosure of Invention
The invention aims to solve the problems in the prior art, and provides processing equipment for preparing colloidal gold test paper by using three-dimensional cell epitopes.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
including the processing platform, still include: the mounting shaft is arranged on the processing table and is provided with raw materials for preparing the colloidal gold test paper; the limiting clamp plate is arranged on the processing table, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate; the sucker is arranged on the limiting clamping plate; the rotating shaft is rotationally connected to the processing table, and a pressing roller is arranged on the rotating shaft; the correcting blocks are circumferentially distributed on the rotating shaft; a cutting unit provided on the processing table; the colloidal gold test paper comprises a bottom plate, an NC film, absorbent paper, a sample pad and a gold mark pad.
Preferably, the NC film is adhered to the middle part of the bottom plate, the water absorbing paper and the sample pad are respectively disposed at two ends of the NC film, the water absorbing paper is attached to the NC film, the gold mark pad is attached to the NC film, and the sample pad is partially covered on the gold mark pad.
Preferably, the processing bench is provided with a clamping plate, the mounting shafts are arranged on the clamping plate, two mounting shafts are arranged, one mounting shaft close to the cutting part is provided with a sample pad roll, and the other mounting shaft far away from the cutting part is provided with a water absorption paper roll and a gold mark pad roll respectively.
Further, the limiting clamp plate is arranged on the clamping plate, the limiting clamp plate is composed of two plates, a half opening is formed in the plate arranged above the limiting clamp plate, through grooves are formed in the plate arranged below the limiting clamp plate, a plurality of groups of sucking discs are arranged, and the sucking discs correspond to the half opening and the through grooves respectively.
Further, a fixed plate is arranged on the processing table, a lifting plate is connected to the clamping plate in a sliding manner, a sucker corresponding to the half opening is arranged on the fixed plate, and a sucker corresponding to the through groove is arranged on the lifting plate.
Preferably, the processing table is slidably connected with a sliding block, the bottom plate slides on the processing table, and the sliding block abuts against the bottom plate.
Further, the gear is rotationally connected to the processing table, an installation seat is arranged on the processing table, the rotating shaft is rotationally connected to the installation seat, and one end of the rotating shaft in the installation seat is rotationally connected with the gear through a transmission belt.
Preferably, an inflator is arranged in the processing table, a round magnetic block is connected in a sliding manner in the inflator, a magnetic ring which is magnetically connected with the round magnetic block is connected outside the inflator in a sliding manner, the magnetic ring is fixedly connected with the sliding block, a cover plate is arranged on the processing table, an inclined angle is arranged at the corner of the cover plate, and the inflator is connected with the cover plate through a vent pipe.
Preferably, a rack is connected in the processing table in a sliding way, the rack is matched with the gear, and the rack is fixedly connected with the sliding block.
Preferably, the application method of the processing equipment for preparing the colloidal gold test paper by using the three-dimensional cell epitope comprises the following steps of:
s1, placing a bottom plate on a processing table, respectively sucking two sides of a water absorbing paper and a gold mark pad by two suckers on the upper surface and the lower surface of a limiting clamping plate, removing base paper on the water absorbing paper and the gold mark pad, and placing the water absorbing paper and the gold mark pad on the bottom plate;
s2, along with the movement of the bottom plate to the cutting part, the compression roller is used for pasting the water absorbing paper with the base paper removed and the gold mark pad on the bottom plate, then the base paper on the sample pad is removed by the sucking disc on the other group of limiting clamping plates, and the sample pad is pasted on the bottom plate and the gold mark pad;
s3, the cutting part cuts the assembled colloidal gold test paper into small pieces.
Compared with the prior art, the invention provides processing equipment for preparing the colloidal gold test paper by using the three-dimensional cell epitope, which has the following beneficial effects:
1. this three-dimensional cell epitope preparation colloidal gold test paper processing equipment, through two upper and lower matched with sucking discs, the backing paper on the absorbent paper, sample pad, the gold mark pad is got rid of to paste absorbent paper, sample pad, gold mark pad on the bottom plate, accurate control absorbent paper, sample pad, gold mark pad paste length, avoid extravagant.
2. According to the processing equipment for preparing the colloidal gold test paper by the three-dimensional cell epitope, the rack is pushed by the sliding block, so that the correcting block rotates, the posture of the bottom plate is kept stable and not inclined, and the subsequent cutting part is convenient for cutting the large plate of the colloidal gold test paper.
3. According to the processing equipment for preparing the colloidal gold test paper by the three-dimensional cell epitope, the round magnetic block is pushed by the sliding block to compress the air in the inflator pump, so that the air in the inflator pump is sprayed to the upper surface of the bottom plate, the surface of the bottom plate is cleaned, and unqualified colloidal gold test paper is prevented from being produced.
The non-related parts of the processing equipment for preparing the colloidal gold test paper by the three-dimensional cell epitope are the same as or can be realized by adopting the prior art, and the invention can accurately paste the water absorbing paper, the gold mark pad and the sample pad according to the length of the bottom plate, thereby avoiding material waste.
Drawings
FIG. 1 is a schematic diagram of the whole processing equipment for preparing colloidal gold test paper by using three-dimensional cell epitopes;
FIG. 2 is a schematic diagram II of the whole processing equipment for preparing colloidal gold test paper by using three-dimensional cell epitopes;
FIG. 3 is a schematic diagram III of the whole processing equipment for preparing colloidal gold test paper by using three-dimensional cell epitopes;
FIG. 4 is a schematic diagram of the enlarged structure of the portion A in FIG. 3 of a processing device for preparing colloidal gold test paper by three-dimensional cell epitopes;
FIG. 5 is a top view of a processing device for preparing colloidal gold test paper from three-dimensional cell epitopes according to the present invention;
FIG. 6 is a cross-sectional view of a processing station of a processing device for preparing colloidal gold test paper by using three-dimensional cell epitopes;
FIG. 7 is a cross-sectional view of an inflator of a processing device for preparing colloidal gold test paper by using three-dimensional cell epitopes;
FIG. 8 is a side view of a processing device for preparing colloidal gold test paper from three-dimensional cell epitopes according to the present invention;
FIG. 9 is a schematic diagram of the processing equipment for preparing the colloidal gold test paper by using the three-dimensional cell epitope, which is provided by the invention, in which the part B is enlarged in FIG. 8;
fig. 10 is a diagram showing the structure of a colloidal gold test strip cut into small pieces by a processing device for preparing a colloidal gold test strip by using a three-dimensional cell epitope.
In the figure: 1. a bottom plate; 2. NC film; 3. a water absorbing paper; 4. a sample pad; 5. a gold mark pad; 6. a processing table; 7. a clamping plate; 8. a mounting shaft; 9. a sliding block; 10. a fixing plate; 11. a mounting base; 12. a rotating shaft; 13. limiting clamping plates; 14. a suction cup; 15. a cover plate; 16. an inclination angle; 17. a cutting section; 18. a press roller; 19. a correcting block; 20. a half-opening; 21. a through groove; 22. an inflator; 23. a vent pipe; 24. a rack; 25. a magnetic ring; 26. a round magnetic block; 27. a gear; 28. a transmission belt; 29. and a lifting plate.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
In the description of the present invention, it should be understood that the terms "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present invention and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Example 1:
referring to fig. 1 to 10, the apparatus includes a processing table 6, and further includes: the mounting shaft 8 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper are arranged on the mounting shaft 8; the limiting clamp plate 13 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate 13; the sucking disc 14 is arranged on the limiting clamping plate 13; the rotating shaft 12 is rotatably connected to the processing table 6, and a press roller 18 is arranged on the rotating shaft 12; the correcting blocks 19 are circumferentially distributed on the rotating shaft 12; a cutting unit 17 provided on the processing table 6; the colloidal gold test paper comprises a bottom plate 1, an NC film 2, water absorbing paper 3, a sample pad 4 and a gold mark pad 5.
In the invention, firstly, a bottom plate 1 is placed on a processing table 6, two suckers 14 on the upper surface and the lower surface of a limiting clamping plate 13 respectively absorb two surfaces of a water absorbing paper 3 and a gold mark pad 5, the water absorbing paper 3 and the gold mark pad 5 are removed, the water absorbing paper 3 and the gold mark pad 5 are placed on the bottom plate 1, the water absorbing paper 3 and the gold mark pad 5 with the water absorbing paper removed are tightly adhered to the bottom plate 1 by a pressing roller 18 along with the movement of the bottom plate 1 to a cutting part 17, then the bottom paper on a sample pad 4 is removed by a sucker 14 on the other group of limiting clamping plates 13, the sample pad 4 is adhered to the bottom plate 1 and the gold mark pad 5, and finally the assembled colloidal gold test paper is cut into small pieces by the cutting part 17; a small cutting knife is arranged in the limiting clamp plate 13, and a worker can set the lengths of the required absorbent paper 3, the sample pad 4 and the gold mark pad 5 and cut the absorbent paper by the cutting knife; the alignment block 19 always ensures that the posture of the base plate 1 is kept stable, and is convenient for the subsequent cutting part 17 to cut.
Example 2:
referring to fig. 1 to 10, the apparatus includes a processing table 6, and further includes: the mounting shaft 8 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper are arranged on the mounting shaft 8; the limiting clamp plate 13 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate 13; the sucking disc 14 is arranged on the limiting clamping plate 13; the rotating shaft 12 is rotatably connected to the processing table 6, and a press roller 18 is arranged on the rotating shaft 12; the correcting blocks 19 are circumferentially distributed on the rotating shaft 12; a cutting unit 17 provided on the processing table 6; the colloidal gold test paper comprises a bottom plate 1, an NC film 2, water absorbing paper 3, a sample pad 4 and a gold mark pad 5; NC film 2 is pasted in the middle part of bottom plate 1, and absorbent paper 3 and sample pad 4 are placed in the both ends of NC film 2 respectively, and absorbent paper 3 laminating mutually with NC film 2, and gold mark pad 5 laminating mutually with NC film 2, and sample pad 4 part covers on gold mark pad 5.
In the invention, when the water absorbing paper 3, the sample pad 4 and the gold mark pad 5 are adhered, the water absorbing paper 3 and the gold mark pad 5 are adhered firstly, and finally the sample pad 4 is adhered, part of the sample pad 4 is adhered to the bottom plate 1, part of the sample pad 4 is arranged above the gold mark pad 5, and part of the gold mark pad 5 which is not covered by the sample pad 4 is covered on the NC film 2.
Example 3:
referring to fig. 1 to 10, the apparatus includes a processing table 6, and further includes: the mounting shaft 8 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper are arranged on the mounting shaft 8; the limiting clamp plate 13 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate 13; the sucking disc 14 is arranged on the limiting clamping plate 13; the rotating shaft 12 is rotatably connected to the processing table 6, and a press roller 18 is arranged on the rotating shaft 12; the correcting blocks 19 are circumferentially distributed on the rotating shaft 12; a cutting unit 17 provided on the processing table 6; the colloidal gold test paper comprises a bottom plate 1, an NC film 2, water absorbing paper 3, a sample pad 4 and a gold mark pad 5; the processing table 6 is provided with a clamping plate 7, the mounting shafts 8 are arranged on the clamping plate 7, two mounting shafts 8 are arranged, one mounting shaft 8 close to the cutting part 17 is provided with a sample pad 4 roll, and the other mounting shaft 8 far away from the cutting part 17 is respectively provided with a water absorbing paper 3 roll and a gold mark pad 5 roll; the limiting clamping plate 13 is arranged on the clamping plate 7, the limiting clamping plate 13 consists of two plates, a half opening 20 is formed in the plate arranged above, a through groove 21 is formed in the plate arranged below, a plurality of groups of sucking discs 14 are arranged, and the groups of sucking discs 14 correspond to the half opening 20 and the through groove 21 respectively; the processing table 6 is provided with a fixed plate 10, the clamping plate 7 is connected with a lifting plate 29 in a sliding way, the sucker 14 corresponding to the half opening 20 is arranged on the fixed plate 10, and the sucker 14 corresponding to the through groove 21 is arranged on the lifting plate 29.
In the invention, a plurality of groups of screw rods and motors are arranged in a processing table 6, screw blocks are rotationally connected to the screw rods, a mechanism formed by the screw rods and the screw blocks is used as a driving source to drive components on the processing table 6 to move and run, wherein a sliding block 9, a fixed plate 10, a sucker 14, a lifting plate 29 and the like are arranged;
the clamping plates 7 are used for fixing the mounting shafts 8, one of the clamping plates 7 is slidably connected to one guide rail on the processing table 6, and one of the clamping plates 7 can be pulled out, so that the roll of the absorbent paper 3, the roll of the gold mark pad 5 and the roll of the sample pad 4 can be replaced conveniently;
the sucking disc 14 is provided with a plurality of sucking nozzles, so that the sucking force on the water absorbing paper 3, the gold mark pad 5 and the sample pad 4 is stronger and more stable;
the sucking disc 14 corresponding to the half opening 20 is arranged on the fixed plate 10, the fixed plate 10 slides on the processing table 6, the sucking disc 14 also slides on the fixed plate 10, and the sucking disc 14 is adsorbed on the upper surfaces of the water absorbing paper 3, the gold mark pad 5 and the sample pad 4 through the half opening 20;
the sucking disc 14 corresponding to the through groove 21 is arranged on the lifting plate 29, the lifting plate 29 slides on the clamping plate 7, the sucking disc 14 adsorbs the bottom paper on the lower surfaces of the water absorbing paper 3, the gold mark pad 5 and the sample pad 4, and then the lifting plate 29 drives the sucking disc 14 to move downwards so as to separate the bottom paper from the water absorbing paper 3, the gold mark pad 5 and the sample pad 4;
the absorbent paper 3, the gold mark pad 5 and the sample pad 4 after the base paper is peeled off are adhered to the bottom plate 1 through the sucker 14 corresponding to the half opening 20 and the fixing plate 10.
Example 4:
referring to fig. 1 to 10, the apparatus includes a processing table 6, and further includes: the mounting shaft 8 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper are arranged on the mounting shaft 8; the limiting clamp plate 13 is arranged on the processing table 6, and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate 13; the sucking disc 14 is arranged on the limiting clamping plate 13; the rotating shaft 12 is rotatably connected to the processing table 6, and a press roller 18 is arranged on the rotating shaft 12; the correcting blocks 19 are circumferentially distributed on the rotating shaft 12; a cutting unit 17 provided on the processing table 6; the colloidal gold test paper comprises a bottom plate 1, an NC film 2, water absorbing paper 3, a sample pad 4 and a gold mark pad 5; the processing table 6 is connected with a sliding block 9 in a sliding way, the bottom plate 1 slides on the processing table 6, and the sliding block 9 is propped against the bottom plate 1; the gear 27 is rotationally connected to the processing table 6, the mounting seat 11 is arranged on the processing table 6, the rotating shaft 12 is rotationally connected to the mounting seat 11, and one end of the rotating shaft 12 arranged in the mounting seat 11 is rotationally connected with the gear 27 through the transmission belt 28; an inflator 22 is arranged in the processing table 6, a round magnetic block 26 is connected inside the inflator 22 in a sliding way, a magnetic ring 25 which is magnetically connected with the round magnetic block 26 is connected outside the inflator 22 in a sliding way, the magnetic ring 25 is fixedly connected with the sliding block 9, a cover plate 15 is arranged on the processing table 6, an inclined angle 16 is arranged at the corner of the cover plate 15, and the inflator 22 is connected with the cover plate 15 through a vent pipe 23; a rack 24 is connected in a sliding way on the processing table 6, the rack 24 is matched with a gear 27, and the rack 24 is fixedly connected with the sliding block 9.
In the invention, a driving source is arranged in a processing table 6 to drive a sliding block 9 to slide in a reciprocating manner, so that the sliding block 9 pushes a bottom plate 1 to move;
when the sliding block 9 pushes the bottom plate 1 to move, the magnetic ring 25 drives the circular magnetic block 26 to synchronously move, so that the circular magnetic block 26 discharges air in the inflator pump 22 into the vent pipe 23, the bottom surface of the cover plate 15 is provided with a gas nozzle, and gas in the vent pipe 23 is sprayed to the bottom plate 1 through the gas nozzle to blow away impurities possibly attached to the water absorbing paper 3, the gold mark pad 5 and the sample pad 4, thereby ensuring the quality of the produced colloidal gold test paper;
the inclined angle 16 on the cover plate 15 is an inwardly convergent edge, when the bottom plate 1 moves below the cover plate 15, the inclined angle 16 guides the bottom plate 1, the posture of the bottom plate 1 is adjusted, cutting is facilitated, the situation that the cut colloidal gold test paper is askew and the quality of the cut colloidal gold test paper is unqualified is avoided;
when the sliding block 9 pushes the bottom plate 1 to move, the rack 24 moves along with the sliding block 9, and when the rack 24 moves to the position right below the mounting seat 11, the rack 24 is meshed with the gear 27, and as the rack 24 continues to move, the gear 27 rotates, and the driving belt 28 drives the rotating shaft 12 to rotate, so that the compression roller 18 can tightly attach the water absorbing paper 3, the gold mark pad 5 and the sample pad 4 to the bottom plate 1, and meanwhile, the bottom plate 1 can be promoted to move towards the cutting part 17;
when the rotating shaft 12 rotates, the correcting block 19 synchronously rotates, the correcting block 19 is a triangle with an edge having radian, when the correcting block 19 rotates, the tip of the correcting block 19 and the narrow edge thereof firstly contact the edge end of the bottom plate 1, along with the rotation of the correcting block 19, the wide bottom of the correcting block 19 gradually contacts the edge end of the bottom plate 1, the edge end of the bottom plate 1 sequentially contacts the narrow edge and the wide edge of the correcting block 19, and the inclined bottom plate 1 is supported to be in a right position under the guidance of the correcting block 19, so that the optimal gesture is maintained, and the subsequent cutting is facilitated.
Example 5:
referring to fig. 1 to 10, a method for using a processing device for preparing colloidal gold test paper from three-dimensional cell epitopes comprises the following steps:
s1, placing a bottom plate 1 on a processing table 6, respectively sucking two sides of a water absorbing paper 3 and a gold mark pad 5 by two suckers 14 on the upper surface and the lower surface of a limiting clamping plate 13, removing the bottom paper on the water absorbing paper 3 and the gold mark pad 5, and placing the water absorbing paper 3 and the gold mark pad 5 on the bottom plate 1;
s2, pushing the bottom plate 1 to the cutting part 17 by the sliding block 9, adhering the water absorbing paper 3 with the bottom paper removed and the gold mark pad 5 on the bottom plate 1 by the pressing roller 18, removing the bottom paper on the sample pad 4 by the sucking disc 14 on the other group of limiting clamping plates 13, and adhering the sample pad 4 on the bottom plate 1 and the gold mark pad 5;
and S3, in the moving process of the bottom plate 1, the posture of the bottom plate 1 is kept stable and not inclined by the aligning block 19 and the inclined angle 16, and finally the assembled colloidal gold test paper is cut into small pieces by the cutting part 17.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (7)
1. The processing equipment for preparing the colloidal gold test paper by using the three-dimensional cell epitope comprises a processing table (6), and is characterized by further comprising: the mounting shaft (8) is arranged on the processing table (6), and raw materials for preparing the colloidal gold test paper are arranged on the mounting shaft (8); the limiting clamp plate (13) is arranged on the processing table (6), and raw materials for preparing the colloidal gold test paper penetrate through the limiting clamp plate (13); the sucking disc (14) is arranged on the limiting clamping plate (13); a rotating shaft (12) is rotatably connected to the processing table (6), and a press roller (18) is arranged on the rotating shaft (12); the correcting blocks (19) are circumferentially distributed on the rotating shaft (12); a cutting unit (17) provided on the processing table (6); the colloidal gold test paper comprises a bottom plate (1), an NC film (2), water absorbing paper (3), a sample pad (4) and a gold mark pad (5);
the NC film (2) is adhered to the middle part of the bottom plate (1), the water absorbing paper (3) and the sample pad (4) are respectively arranged at two ends of the NC film (2), the water absorbing paper (3) is adhered to the NC film (2), the gold mark pad (5) is adhered to the NC film (2), and the sample pad (4) is partially covered on the gold mark pad (5);
the processing table (6) is provided with clamping plates (7), the mounting shafts (8) are arranged on the clamping plates (7), two mounting shafts (8) are arranged, one mounting shaft (8) close to the cutting part (17) is provided with a sample pad (4) roll, and one mounting shaft (8) far away from the cutting part (17) is respectively provided with a water absorption paper (3) roll and a gold mark pad (5) roll;
the limiting clamp plate (13) is arranged on the clamping plate (7), the limiting clamp plate (13) is composed of two plates, a half opening (20) is formed in the plate arranged above the limiting clamp plate, a through groove (21) is formed in the plate arranged below the limiting clamp plate, a plurality of groups of sucking discs (14) are arranged, and the sucking discs (14) correspond to the half opening (20) and the through groove (21) respectively.
2. The processing device for preparing the colloidal gold test paper by using the three-dimensional cell epitope according to claim 1, wherein a fixed plate (10) is arranged on the processing table (6), a lifting plate (29) is connected to the clamping plate (7) in a sliding manner, a sucker (14) corresponding to the half-opening (20) is arranged on the fixed plate (10), and a sucker (14) corresponding to the through groove (21) is arranged on the lifting plate (29).
3. The processing device for preparing the colloidal gold test paper by using the three-dimensional cell epitope according to claim 1, wherein a sliding block (9) is connected to the processing table (6) in a sliding manner, the bottom plate (1) slides on the processing table (6), and the sliding block (9) is propped against the bottom plate (1).
4. A processing device for preparing colloidal gold test paper by using three-dimensional cell epitope according to claim 3, characterized in that, a gear (27) is rotationally connected with the processing table (6), a mounting seat (11) is arranged on the processing table (6), the rotating shaft (12) is rotationally connected with the mounting seat (11), and one end of the rotating shaft (12) arranged in the mounting seat (11) is rotationally connected with the gear (27) through a driving belt (28).
5. A processing device for preparing colloidal gold test paper by using three-dimensional cell epitopes according to claim 3, characterized in that an inflator (22) is arranged in the processing table (6), a round magnetic block (26) is connected in a sliding manner in the inflator (22), a magnetic ring (25) magnetically connected with the round magnetic block (26) is connected outside the inflator (22) in a sliding manner, the magnetic ring (25) is fixedly connected with the sliding block (9), a cover plate (15) is arranged on the processing table (6), an inclined angle (16) is arranged at a corner of the cover plate (15), and the inflator (22) is connected with the cover plate (15) through a vent pipe (23).
6. The processing device for preparing the colloidal gold test paper by using the three-dimensional cell epitope according to claim 4, wherein a rack (24) is connected in a sliding manner on the processing table (6), the rack (24) is matched with a gear (27), and the rack (24) is fixedly connected with a sliding block (9).
7. The method for using the processing equipment for preparing the colloidal gold test paper by using the three-dimensional cell epitope according to claim 1, which is characterized by comprising the following steps of:
s1, placing a bottom plate (1) on a processing table (6), respectively sucking two surfaces of a water absorbing paper (3) and a gold mark pad (5) by two suckers (14) on the upper surface and the lower surface of a limiting clamp plate (13), removing base paper on the water absorbing paper (3) and the gold mark pad (5), and placing the water absorbing paper (3) and the gold mark pad (5) on the bottom plate (1);
s2, along with the movement of the base plate (1) to the cutting part (17), the press roll (18) is used for adhering the water absorbing paper (3) with the base paper removed and the gold mark pad (5) to the base plate (1), then the suckers (14) on the other group of limiting clamping plates (13) are used for removing the base paper on the sample pad (4), and the sample pad (4) is adhered to the base plate (1) and the gold mark pad (5);
s3, cutting the assembled colloidal gold test paper into small pieces by a cutting part (17).
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| CN202311388589.2A CN117400338B (en) | 2023-10-25 | 2023-10-25 | Processing equipment and method for preparing colloidal gold test paper by three-dimensional cell epitope |
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| CN202311388589.2A CN117400338B (en) | 2023-10-25 | 2023-10-25 | Processing equipment and method for preparing colloidal gold test paper by three-dimensional cell epitope |
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| CN117400338B true CN117400338B (en) | 2024-03-22 |
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| CN117400338A (en) | 2024-01-16 |
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