CN117396173A

CN117396173A - Patch for skin application and method for producing patch for skin application

Info

Publication number: CN117396173A
Application number: CN202280037356.5A
Authority: CN
Inventors: 丁敏雄; 张明勋
Original assignee: Biosensor Laboratories Inc
Current assignee: Biosensor Laboratories Inc
Priority date: 2021-11-01
Filing date: 2022-10-27
Publication date: 2024-01-12

Abstract

The present invention relates to a patch for skin application and a method for manufacturing the patch for skin application. The invention comprises the following steps: a substrate; and a thin film disposed over the substrate and having a predetermined thickness deviation range.

Description

Patch for skin application and method for producing patch for skin application

Technical Field

The present invention relates to a patch to be applied to the skin and a method for manufacturing the patch.

Background

In general, skin patches are used for skin beauty such as blocking ultraviolet rays or moisturizing, which are impregnated with various formulations such as essence in general nonwoven fabrics and applied to the skin, or applied to the skin in a hydrogel (hydro gel) state.

Further, as the skin patch, a gel (gel) patch using agar (agar) or starch or the like is used, but as described above, when a general nonwoven fabric impregnated with various formulations such as essence is attached to the skin (for example, face or the like), the amount of evaporated air is large, and the patch is completely dried after 15 minutes to 20 minutes, problems such as peeling from the skin, and decrease in percutaneous absorption of the formulation occur due to deterioration of adhesiveness.

In addition, in the case of the hydrogel patch, adhesiveness to skin is lowered, chemical skin problems often occur due to an adhesive preparation for providing adhesiveness, products can be produced only by a limited preparation, and a manufacturing process is complicated and curing and the like requires a long time, so there is a problem that manufacturing cost is increased.

Also, in the case of a gel patch using agar, starch, or the like, since a net is used as a support for the gel, the support cannot fully support the gel, so that when a user attaches it to the skin, its shape becomes scattered or damaged, and the residue becomes powder after drying, and thus there is a problem in that it is difficult to keep clean.

Recently, with the active development of indoor activities and leisure industries such as golf, mountain climbing, hiking (hiking), etc., it is required to manufacture a patch that can be used during an activity or outdoors.

Disclosure of Invention

Technical problem to be solved by the invention

The purpose of the present invention is to provide a patch for skin application having high skin adhesion and transparency, and a method for producing the same. However, these problems are exemplary, and the scope of the present invention is not limited thereto.

Technical proposal

An aspect of the present invention provides a patch for skin attachment, comprising: a substrate; and a thin film disposed over the substrate and having a predetermined thickness deviation range.

Advantageous effects

In the patch for skin attachment and the method of manufacturing the same according to an embodiment of the present invention, the film of the patch for skin attachment is manufactured to have a thickness deviation so that the water permeability and the air permeability are improved in the area where the thickness is thin. Therefore, the feeling of use can be improved, and the comfort when attached to the skin can be improved.

The patch for skin attachment according to an embodiment of the present invention and the method for manufacturing the same can improve functionality. Since the portion in contact with the skin contains the active ingredient delivered to the skin, no skin problem is caused, and the cosmetic effect can be improved. And, the film containing the ultraviolet blocking substance may have high water-proof performance, high water-proof retention performance, and high ultraviolet blocking performance.

Drawings

Fig. 1 is a diagram showing a patch for skin attachment according to an embodiment of the present invention.

FIG. 2 is a cross-sectional view and an enlarged view taken along line II-II of FIG. 1.

Fig. 3 is an enlarged view showing a modification of fig. 2.

Fig. 4 is a diagram showing a step of printing the first layer of fig. 2.

Fig. 5 is a diagram showing a step of printing the second layer of fig. 2.

Fig. 6 to 9 are enlarged views showing modifications of fig. 5.

Fig. 10 and 11 are diagrams of a method of manufacturing a patch for skin attachment according to an embodiment of the present invention.

Fig. 12 and 13 are graphs showing the ultraviolet blocking effect of the patch for skin attachment of fig. 1.

Detailed Description

Further, the film may have a water permeability or an air permeability, which may be higher in a region where the thickness of the film is thin than in a region where the thickness of the film is thick.

And, the film may include: a first layer comprising a first base adjacent to the substrate and having a first thickness and a first recess having a thickness thinner than the first thickness; and a second layer disposed at one side of the first layer and including a second substrate having a second thickness and a second recess having a thickness thinner than the second thickness.

And, the first recess and the second recess may be provided to at least partially overlap.

And, the second concave portion may be provided between adjacent first concave portions.

And, at least one of the first recess and the second recess may have a mesh shape on a plane of the substrate.

And, the second layer may contain an active ingredient that is delivered to the skin.

Another aspect of the present invention provides a method for manufacturing a patch for skin attachment, comprising: a step of preparing a substrate, and a step of screen-printing a raw material onto an upper surface of the substrate to form a thin film; the step of forming a thin film includes: a step of printing a first layer formed with first recesses by printing the raw material onto a first grid, and a step of printing a second layer provided on the first layer and formed with second recesses by printing the raw material onto a second grid.

And, in the printing of the second layer, the second mesh may be disposed to overlap the first mesh, or the second mesh may be disposed between the first meshes.

And, in the step of printing the second layer, the raw material including the active ingredient delivered to the skin may be printed.

DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION

While the invention is susceptible to various modifications and alternative embodiments, specific embodiments thereof are shown in the drawings and will be described in detail herein. The effects and features of the present invention and a method of achieving them will become apparent with reference to embodiments described in detail later and the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below and may be embodied in various forms.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings, and the same or corresponding components will be given the same reference numerals, and repetitive description thereof will be omitted.

In the following embodiments, terms such as first and second, etc. are used for the purpose of distinguishing one component from another and are not intended to be limiting.

In the following embodiments, the singular forms of expression include the plural forms of expression unless the context clearly dictates otherwise.

In the following embodiments, terms such as include or have denote the presence of features or components recited in the specification, the possibility of adding more than one other feature or component is not excluded in advance.

In the following embodiments, when a portion of a film, a region, a component, or the like is over or on another portion, not only the case where it is directly over another portion but also the case where the film, the region, the component, or the like is interposed therebetween are included.

In the drawings, the size of the components may be enlarged or reduced for convenience of explanation. For example, since the sizes and thicknesses of the respective structures shown in the drawings are arbitrarily shown for convenience of explanation, the present invention is not necessarily limited to the shown drawings.

Fig. 1 is a view showing a patch for skin attachment according to an embodiment of the present invention, and fig. 2 is a sectional view and an enlarged view taken along ii-ii of fig. 1.

Referring to fig. 1 and 2, in the patch 1 for skin attachment, the film 100 is attached to the skin, and an active ingredient can be delivered to the skin or the skin can be protected from the external environment according to the function of the film 100.

The patch 1 for skin attachment may have flexibility to improve adhesion to the skin. The patch for skin attachment 1 may have elasticity to be attached to various parts of the body.

The patch 1 for skin application may have various shapes and sizes according to the application site or purpose of use. For example, the patch 1 for skin attachment may have various shapes such as a polygon, a circle, and an ellipse. The patch 1 for skin application may have various sizes according to the coverage area. However, for convenience of explanation, an embodiment in which the patch 1 for skin attachment shown in fig. 1 has a rectangular shape will be mainly explained below.

The patch for skin attachment 1 may have a substrate 10 and a film 100.

The substrate 10 serves to support the film 100, and one surface of the substrate 10 is exposed to the outside, and one surface of the substrate 10 may face the film 100.

As an alternative embodiment, the intermediate layer 15 may be provided between the substrate 10 and the film 100. The intermediate layer 15 may have an adhesive force such that the film 100 is attached to the substrate 10. Film 100 may be supported on substrate 10 by intermediate layer 15.

The adhesion of the intermediate layer 15 can be changed by adding substances. After the film 100 is attached to the skin, the adhesive force of the intermediate layer 15 may be reduced so that the substrate 10 is easily removed from the film 100. For example, the intermediate layer 15 is brought into contact with the solution, whereby the adhesive force thereof is lowered, and when the adhesive force of the intermediate layer 15 is lowered, the substrate 10 can be easily separated from the film 100.

As an example, the intermediate layer 15 has degradability and can be decomposed by a liquid. For example, the intermediate layer 15 may be dissolved by water, and when the substrate 10 is sufficiently wetted by water, a portion of the intermediate layer 15 may be decomposed. When the intermediate layer 15 is decomposed, the adhesive force between the substrate 10 and the film 100 may be reduced, and the substrate 10 may be easily separated from the film 100.

As another example, the intermediate layer 15 may have a lower adhesion force than the second layer 120 of the film 100. When the substrate 10 is removed after the second layer 120 of the film 100 is attached to the skin, the substrate 10 can be easily separated since the adhesive force between the second layer 120 and the skin is lower than the adhesive force between the substrate 10 and the intermediate layer 15.

As an alternative embodiment, the patch for skin attachment 1 may further include a backing 20. The backing 20 may cover one surface of the film 100 to protect the surface of the film 100 that is attached to the skin. When film 100 is applied to the skin, backing 20 may be separated from film 100.

Film 100 may be disposed over substrate 10. Film 100 may be disposed between substrate 10 and backing 20. The film 100 may have flexibility and elasticity so as to be in close contact with the skin to which the film 100 is attached, and may be formed of a biocompatible material.

Film 100 may have a multi-layer structure, and as an example, film 100 may include first layer 110 and second layer 120.

The first layer 110 may be disposed adjacent to the substrate 10. The first layer 110 may be formed of a biocompatible substance.

Depending on the application of the patch 1 for skin attachment, the first layer 110 may additionally contain an active substance (not shown).

As an example, the first layer 110 may include an ultraviolet blocking substance. The patch 1 for skin application can block ultraviolet rays in the area to which the film 100 is applied.

As another example, the first layer 110 is provided to be transparent, and may have a mark or a symbol (not shown) printed therein. The marks or indicia may be clearly displayed according to the transparency of the first layer 110 of the film 100 applied to the skin.

The second layer 120 contacts the skin and may have adhesive properties. The second layer 120 may be supported by the backing 20 and may secure the first layer 110 to the skin S.

As an alternative embodiment, the second layer 120 may contain the effective component EM. The effective component EM may be defined as a substance delivered to the inside of the body through the skin of the adhesive film 100, and may be set in various ways such as medicines, cosmetics, and functional substances.

The first layer 110 may have a first thickness T1 and the second layer 120 may have a second thickness T2 thinner than the first layer 110.

The intermediate layer 15 may have a third thickness T3, and the third thickness T3 may be set smaller than the second thickness T2. The intermediate layer 15 is disposed between the first layer 110 and the substrate 10, and may have a lower adhesive force than the second layer 120.

The adhesion of the intermediate layer 15 may be changed by adding substances. When the additive substance is absorbed by the intermediate layer 15, the adhesive force of the intermediate layer 15 may be lowered. As an example, when the liquid additive substance is absorbed by the intermediate layer 15, the shape of the intermediate layer 15 is changed to gel or liquid so that the substrate 10 can easily slide on the film 100.

Fig. 3 is an enlarged view showing a modification of fig. 2. Fig. 3 is an enlarged view for region a in fig. 2.

Referring to fig. 3, the patch for skin attachment may include a film 100A disposed between the substrate 10 and the backing 20. An intermediate layer 15 may be disposed between the substrate 10 and the film 100A.

The film 100A may have a single-layer structure, and a region adjacent to the liner 20 may have an adhesive force to adhere to the skin.

As an example, the film 100A may be made of polyurethane as the first layer 110 described above.

As an alternative embodiment, the film 100A may contain an effective component EM. As an example, the active ingredient EM may be set in various forms such as a drug, a cosmetic, and a functional substance that can be delivered into the body through the skin S.

As another example, the active ingredient EM may contain a substance for protecting the skin S. As an example, the active ingredient EM may be set to be a substance (for example, an ultraviolet blocking agent) that is not delivered to the skin S and that can protect the skin from the external environment.

Fig. 4 is a diagram showing a step of printing the first layer of fig. 2, and fig. 5 is a diagram showing a step of printing the second layer of fig. 2.

Referring to fig. 4 and 5, the film 200 may be formed using a screen printing method well known in the art.

As an example, the first layer 210 and the second layer 220 constituting the film 200 may be laminated and printed.

The first layer 210 may be formed in such a manner that the first raw material RM1 is printed onto the substrate 10 through the first mesh SC 1. At this time, the first layer 210 may be provided to have water permeability or air permeability.

Referring to the enlarged view of part B of fig. 4, the first layer 210 may be formed of the first substrate 211 having the first thickness D1 and the first recess 212 having the first recess thickness D1' by the number and interval of the plurality of holes provided at the first mesh SC 1.

The first layer 210 may have a thickness deviation according to the width W1 of the first recess 212 and the arrangement interval. Depending on the thickness deviation described above, each portion of the first layer 210 may have a different level of water permeability or air permeability.

Referring to fig. 5, the second layer 220 may be disposed over the first layer 210.

The second layer 220 may be formed in such a manner that the second raw material RM2 is printed onto the first layer 210 through the second mesh SC 2. At this time, the second layer 220 may be provided to have water permeability or air permeability.

As shown in the enlarged view of part C of fig. 5, the second layer 220 may be formed of the second substrate 221 having the second thickness D2 and the second recess 222 having the second recess thickness D2' by the number and interval of the plurality of holes provided in the second mesh SC 2.

Since the first layer 210 and the second layer 220 are sequentially laminated and form one thin film 200, the second layer 220 may be formed to have a thickness deviation according to the width W2 and the arrangement interval of the second concave portion 222, the width W1 and the arrangement interval of the first concave portion 212, and whether the second concave portion 222 overlaps with the first concave portion 212.

The film 200 may have a predetermined thickness deviation range, and may have a thickness obtained by adding up the first layer 210 and the second layer 220. The above-mentioned predetermined thickness range refers to a thickness range from the minimum recess thickness Dd to the film thickness Df.

Accordingly, the film 200 is improved in water permeability or air permeability for the portion having the minimum recess thickness Dd and the portion having the thickness smaller than the film thickness Df. That is, the water permeability or air permeability at the portion where the thickness of the film 200 is relatively thin can be improved.

According to an embodiment, as shown in fig. 5, the film 200 may be disposed in such a manner that the first recess 212 and the second recess 222 overlap.

The first layer 210 is printed through the first mesh SC1, and a first substrate 211 and a first recess 212 are formed in the first layer 210. The second layer 220 is printed on the first layer 210 through the second mesh SC2, and the second layer 220 may be formed such that the second recess 222 faces the first recess 212 and the second substrate 221 faces the first substrate 211.

The first recess 212 and the second recess 222 may have a preset depth and width, respectively, according to the application amount of raw materials or the kind of mesh screen (mesh screen).

For example, the combined thickness of the first recess thickness D1 'and the second recess thickness D2' may be the minimum recess thickness Dd, and the combined thickness of the first thickness D1 and the second thickness D2 may be the film thickness Df.

By the overlapping of the first concave portion 212 and the second concave portion 222, the water permeability or air permeability of the film 200 at the portion having the minimum concave thickness Dd can be improved.

As an example, the recess depth of the first recess 212 may be set smaller than the recess depth of the second recess 222.

The second recess 222 is recessed deeper by overlapping with the first recess 212, and thus the second recess thickness D2' between the second recess 222 and the first recess 212 can be thinned.

The second layer 220 may be configured to have a lower water permeability or air permeability than the first layer 210. As the second recess thickness D2' becomes thinner, the proportion of the second layer 220 at the portion having the minimum recess thickness Dd decreases, and the water permeability or air permeability of the film 200 may be improved.

As an example, the width W1 of the first concave portion 212 may be set to be equal to or greater than the width W2 of the second concave portion 222.

The second recess 222 may overlap the first recess 212, and a width W2 of the second recess is provided to be stackable within a width W1 of the first recess 212. The layered structure of the first layer 210 and the second layer 220 can be made firm because the first recess 212 is stacked with the second recess 222 so as to be recessed deeper.

Thereby, the film 200 can be formed to have a thinner minimum recess thickness Dd, and durability and elasticity of the portion having the film thickness Df can be improved.

The film 200 is provided to have thickness deviation, durability, and elasticity, so that it is possible to improve the attaching ability of the film 200 to the skin curve and to improve the wearability of the user.

Fig. 6 to 9 are enlarged views showing modifications of fig. 5. Referring to fig. 6 to 9, thickness deviation of the thin film will be described.

Referring to fig. 6, the second recesses 222A of the film 200A may be disposed between adjacent first recesses 212A.

As an example, the film 200A may be formed such that the second recess 222A and the first substrate 211A face each other and the second substrate 221A and the first recess 212A face each other.

The first layer 210A is formed on the substrate 10 by screen printing, and the second layer 220A is printed thereon, and the second recesses 222A may be disposed to be offset from the first recesses 212A.

The first recess 212A and the second recess 222A may have a preset depth and width, respectively, according to the coating amount of raw materials or the kind of mesh screen.

For example, the combined thickness of the first thickness D1 and the second recess thickness D2 'may be the minimum recess thickness Dd, and the combined thickness of the first recess thickness D1' and the second thickness D2 may be the film thickness Df.

The film 200A may have improved water permeability or air permeability at the portion having the minimum recess thickness Dd.

As an example, the recess depth of the first recess 212A may be set smaller than the recess depth of the second recess 222A.

The second recess 222A is recessed deep, and the second recess thickness D2' may be thinned by the first substrate 211A facing each other with the second recess 222A.

The second layer 220A may be configured to have a lower water permeability or air permeability than the first layer 210A. As the second recess thickness D2' becomes thinner, the proportion of the second layer 220A at the portion having the minimum recess thickness Dd decreases, and the water permeability or air permeability of the film 200A can be greatly improved.

The second layer 220A has low water permeability and/or air permeability, but may have high durability. Thus, the second substrate 221A may be positioned on the upper side of the first concave portion 212A to improve durability and elasticity of the film 200A. The wearability of the film 200A when it is attached to the skin can be improved.

On the other hand, the second layer 220A may be provided to have higher water permeability or air permeability than the first layer 210A. At this time, in the portion having the film thickness Df, since the thickness D2 of the second layer 220A is a maximum value and the thickness D1' of the first layer 210A is a minimum value, the water permeability or air permeability can be improved.

As an example, the width W1 of the first concave portion 212A may be set to be equal to or smaller than the width W2 of the second concave portion 222A.

The second recess 222A is supported by the first substrate 211A located at the lower side, and thus the layered structure of the first layer 210 and the second layer 220 can be made strong. Thus, the film 200A may have improved durability and elasticity at the portion having the film thickness Df.

Referring to fig. 7, as in fig. 6, the second concave portions 222B are disposed between adjacent first concave portions 212B, and the width W1 of the first concave portions 212B may be set smaller than the width W2 of the second concave portions 222.

Since the width of the second base 221B is wider than the width W1 of the first recess 212B, a recess is induced in the center portion of the second base 221B by the first recess 212B, so that the third recess 223B can be formed.

The film 200B may have a recess thickness DB induced by the overlapping of the first recess 212B and the third recess 223B.

For example, the combined thickness of the first thickness D1 and the second recess thickness D2 'is the minimum recess thickness Dd, the combined thickness of the first recess thickness D1' and the third recess thickness D2″ is the induced recess thickness DB, and the combined thickness of the first thickness D1 and the second thickness D2 may be the film thickness Df.

The thin film 200B may be thinned at the portion having the minimum recess thickness Dd and at the portion having the derived recess thickness DB. Since the number of thin portions of the film 200B increases, the water permeability or air permeability can be improved.

Referring to fig. 8, the width W1 of the first recess 212C may be set to be greater than the width W2 of the second recess 222C, and the second recess 222C may be provided in plurality overlapping within the width W1 of the first recess 212C.

As an example, the film 200C may be formed such that the arrangement interval of the first concave portions 212C of the first layer 210C is greater than the arrangement interval of the second concave portions 222C of the second layer 220C.

The first layer 210C is printed onto the substrate 10 through the first mesh SC1, and a first base 211C and a first recess 212C are formed in the first layer 210C. The second layer 220C is printed onto the first layer 210C through the second mesh SC2, and the mesh interval of the second mesh SC2 may be smaller than that of the first mesh SC 1.

The thin film 200C may have a minimum recess thickness Dd at a portion where the first recess 212C overlaps the second recess 222C, and a maximum thin film thickness Df at a portion where the first substrate 211C overlaps the second substrate 221C.

The film 200C may include more portions thinner than the film thickness Df in the same number as the second concave portions 222C, and thus may improve water permeability or air permeability.

As an example, the second layer 220C may have a lower water permeability or air permeability than the first layer 210C. The film 200C may have improved water permeability or breathability, particularly at the plurality of second recesses 222C opposite the first substrate 211C.

The second layer 220C may have high durability due to low water permeability and/or air permeability. The film 200C may improve durability, elasticity, and wearability by densely disposing a plurality of second substrates 221C.

In contrast, the second layer 220C may be configured to have a higher water permeability or air permeability than the first layer 210C. The film 200C may have improved water or air permeability, particularly at the plurality of second recesses 222C overlapping the first recesses 212C.

Referring to fig. 9, the width W1 of the first concave portion 212D may be set smaller than the width W2 of the second concave portion 222D, and a plurality of first concave portions 212D may be overlapped within the width W2 of the second concave portion 222D.

As an example, the film 200D may be formed such that the arrangement interval of the first concave portions 212D of the first layer 210D is smaller than the arrangement interval of the second concave portions 222D of the second layer 220D.

The first layer 210D is printed onto the substrate 10 through the first mesh SC1, and a first base 211D and a first recess 212D are formed in the first layer 210D. The second layer 220D is printed onto the first layer 210D through the second mesh SC2, and the mesh interval of the second mesh SC2 may be greater than that of the first mesh SC 1.

The thin film 200D may have a minimum recess thickness Dd at a portion where the first recess 212D overlaps the second recess 222D, and may have a maximum thin film thickness Df at a portion where the first substrate 211D overlaps the second substrate 221D.

The overlapping portion of the second concave portion 222D and the first concave portion 212D is included in the second concave portion 222D, and the thin portion of the film 200D may have improved water permeability or air permeability due to the second concave portion 222D.

As an example, the second layer 220D may have a lower water permeability or air permeability than the first layer 210D. At this time, since the water permeability and/or air permeability is high at the portion having the first thickness D1' of the first layer 210D, the film 200D may have improved water permeability or air permeability at the portion where the plurality of first concave portions 212D overlap the second concave portions 222D.

The second layer 220D may have high durability due to low water permeability and/or air permeability. Since the first layer 210D includes a plurality of first recesses 212D, durability is reduced, but such first layer 210D supports the second layer 220D to make the layered structure firm. Thus, durability, elasticity, and wearability of the film 200D can be improved.

Referring to fig. 4, 5, 10 and 11, the method of manufacturing the patch 1 for skin attachment may include a step S10 of preparing a substrate and a step S20 of forming a thin film.

In step S10 of preparing the substrate, the substrate 10 may be set to be suitable for screen printing of the film 200, and the substrate 10 and the film 200 may be easily separated from each other.

The step S20 of forming the thin film may include a step S21 of printing the first layer and a step S22 of printing the second layer.

Referring again to fig. 5, in the step S21 of printing the first layer, the first layer 210 is formed by printing the first raw material RM1 to the first mesh SC1, and the first layer 210 may have a thickness range set from the first thickness D1 to the first recess thickness D1'.

In the step S22 of printing the second layer, the second layer 220 is formed on the upper surface of the first layer 210 by printing the second raw material RM2 onto the second mesh SC 2.

In the step S22 of printing the second layer, the second mesh SC2 may be disposed to overlap the first mesh SC1, or the second mesh SC2 may be disposed between the first meshes SC 1.

Thus, the second layer 220 may be formed to have a second thickness D2 and a second recess thickness D2' according to the arrangement and width of the second recess 222 and the first recess 212.

In the step S22 of printing the second layer, a second raw material RM2 containing an active ingredient delivered to the skin may be printed. The active ingredient is defined as a substance that is delivered through the skin into the body and can be set in various ways such as pharmaceuticals, cosmetics, functional substances, etc. Thus, when the user attaches the film 200 to the skin, the skin receives the active ingredient from the second layer 220, and can produce skin beauty and health assistance effects.

Since the film 200 is used to adhere to the skin, it is provided to drain moisture such as sweat generated from the skin and evaporate the moisture to the outside of the film 200. Therefore, performance tests on the water permeability are required.

The water permeability test of the film 200 is performed according to the water-film contact method. The water film contact method is to contain water in the experimental container to the maximum so that there is almost no air layer between the film 200 provided at the upper part of the container and the water. Thereby, air resistance to the film 200 can be removed and a water permeability test can be performed.

As a result of performing the water permeability test by the above method under the temperature condition of 32.2 ℃, the water permeability of the film 200 was measured as 7460g/m ² * And (3) days. Comparing the result with the actual perspiration amount, the performance of the film 200 against perspiration and evaporation can be confirmed.

Generally, the amount of perspiration at rest in a cool environment is 270g/m ² * The perspiration during extreme exercises is 2880g/m ² * Day (based on 20deg.C), while the sweat yield during exercise in a relatively hot environment is 5500g/m ² * And (3) days. Since the water permeability of the film 200 according to an embodiment of the present invention is 7460g/m ² * It was confirmed that most of sweat generated from the skin can be discharged to the outside of the film 200 and evaporated.

The patch for skin attachment in fig. 12 and 13 may contain an ultraviolet blocking substance in a film, and may have ultraviolet blocking property as well as moisture resistance (fig. 12) and blocking holding force (fig. 13). In the graph, the x-axis represents wavelength and the y-axis is defined as the blocking rate.

When the thickness of the film of the patch for skin attachment was 25 μm, the ultraviolet blocking coefficient (UPF) of the film was 343, and the ultraviolet B (UV-B) blocking rate was 99.9%, and the ultraviolet Sup>A (UV-A) blocking rate was 95.8%.

When the thickness of the film of the patch for skin attachment was 35 μm, the Ultraviolet Protection Factor (UPF) of the film was 429, and the UV-B blocking rate was 99.9%, and the UV-A blocking rate was 97.4%.

In the moisture resistance test, the patch for skin application was fixed in a 96-well plate (well plate), and an experimental environment in which both the inner surface and the outer surface of the film of the patch for skin application were immersed in water was formed. The water-in (20 minutes) and the drying (20 minutes) were repeatedly performed.

In the graph of fig. 12, water-in and drying were performed 8 times for 160 minutes, 16 times for 320 minutes, 24 times for 480 minutes, and 32 times for 640 minutes. Even if water and drying are repeatedly performed on the patch for skin attachment, the ultraviolet blocking efficiency is not lowered. In particular, it has been confirmed that even if water-in and drying are repeatedly performed on the patch for skin application, barrier efficiency of almost 100% is maintained in the UV-B band and the UV-Sup>A band of 390nm or less.

Further, even if physical stimulus is applied to the patch for skin application by using ultrasonic waves, the ultraviolet blocking efficiency is not lowered.

In the barrier retention test, a patch for skin attachment was attached to the skin, and the ultraviolet blocking effect was measured at the initial time and after 12 hours. Even if the patch for skin attachment is attached to the skin, the ultraviolet ray blocking efficiency does not decrease after 12 hours.

The uv blocking product in the form of a skin should be applied every 2 hours to maintain uv blocking properties. This is because even when a cream-like ultraviolet blocking product is applied, the blocking rate is lowered due to sweat, physical contact, lowering of the efficiency of the ultraviolet blocking agent, and absorption of the ultraviolet blocking agent by the skin.

With the patch for skin attachment of the present invention, the ultraviolet blocking ability can be maintained during the attachment of the patch to the skin. Unlike the conventional cream-like ultraviolet blocking agent, the patch for skin attachment of the present invention does not decrease in ultraviolet blocking efficiency due to an external environment such as water after once attachment, and can continuously block ultraviolet rays.

Table 1 below shows the experimental results of confirming whether the following test items were detected after exposing the patch for skin attachment of the present invention to water for 24 hours.

The patch for skin application of the present invention may be selected from components having ultraviolet absorbing/blocking functions. In this test, a plurality of patches for skin application containing at least one of the components of table 1 were used as targets, and the following components were not detected even when exposed to water for a long period of time in each test.

TABLE 1

The above-mentioned components are not detected even if the patch for skin application of the present invention is exposed to water for a long period of time. It was confirmed that the above components were contained in the film and did not leak to the outside.

Even if the patch for skin attachment according to the present invention is exposed to the external environment, the components do not leak, and thus skin problems can be reduced.

As described above, the present invention has been described with reference to the embodiments shown in the drawings, but this is merely exemplary, and it will be understood by those of ordinary skill in the art that various modifications and other equivalent embodiments may be implemented. The true technical scope of the invention should therefore be subject to the technical idea of the appended claims.

Claims

1. A patch for skin attachment, comprising:

a substrate; and

and the film is arranged above the substrate and has a preset thickness deviation range.

2. The patch for skin attachment according to claim 1, wherein,

the film has a water permeability or air permeability,

the water permeability or the air permeability is higher in a region where the thickness of the film is thin than in a region where the thickness of the film is thick.

3. The patch for skin attachment according to claim 1, wherein,

the film comprises:

a first layer adjacent to the substrate and comprising a first base having a first thickness and a first recess having a thickness thinner than the first thickness; and

and a second layer disposed on one side of the first layer and including a second substrate having a second thickness and a second recess having a thickness thinner than the second thickness.

4. The patch for skin attachment according to claim 3, wherein,

the first recess and the second recess are arranged to at least partially overlap.

5. The patch for skin attachment according to claim 3, wherein,

the second recesses are disposed between adjacent ones of the first recesses.

6. The patch for skin attachment according to claim 3, wherein,

at least one of the first recess and the second recess has a mesh shape on a plane of the substrate.

7. The patch for skin attachment according to claim 3, wherein,

the second layer comprises an active ingredient for delivery to the skin.

8. A method for manufacturing a patch for skin application, comprising:

a step of preparing a substrate; and

a step of screen-printing a raw material onto an upper surface of the substrate to form a thin film,

the step of forming a thin film includes:

a step of printing a first layer formed with first recesses by printing the raw material onto a first grid; and

a step of printing a second layer by printing the raw material onto a second grid,

wherein the second layer is disposed on the first layer and is formed with a second recess.

9. The method for producing a patch for skin attachment according to claim 8, wherein,

in the step of printing out the second layer, the second grid is disposed to overlap with the first grid or the second grid is disposed between the first grids.

10. The method for producing a patch for skin attachment according to claim 8, wherein,

in the step of printing the second layer, printing is performed with the raw material containing an active ingredient delivered to the skin.