CN117388334A

CN117388334A - Electronic skin and sweat detection method and sweat detection system

Info

Publication number: CN117388334A
Application number: CN202311281579.9A
Authority: CN
Inventors: 李雪; 薄拾; 刘博�; 赵瑞刚; 王凯; 曹盼
Original assignee: Xi'an Tianhe Defense Technology Co ltd
Current assignee: Xi'an Tianhe Defense Technology Co ltd
Priority date: 2023-09-28
Filing date: 2023-09-28
Publication date: 2024-01-12

Abstract

The application discloses an electronic skin, sweat detection method and sweat detection system, and belongs to the technical field of monitoring. Wherein, this electron skin includes: sweat collecting device, sweat detecting device and signal transmission device; the sweat collecting device is used for collecting sweat on the skin surface of a user; the sweat detection device comprises a plurality of sweat sensors and a signal processor; each sweat sensor is used for carrying out electrochemical measurement on the component to be detected corresponding to the sweat sensor in sweat and outputting an electric signal; the signal processor is used for processing the electric signals output by the sweat sensors to obtain content information of each component to be detected; the signal transmission device is used for transmitting the content information of each component to be detected to the external equipment. The sweat components can be detected and monitored in real time through the electronic skin, so that the physiological activities and metabolic conditions in the human body can be reflected, and the health condition of the user can be monitored.

Description

Electronic skin and sweat detection method and sweat detection system

Technical Field

The application belongs to the technical field of monitoring, and particularly relates to an electronic skin and sweat detection method and a sweat detection system.

Background

Under the background of the current technical development, the noninvasive health monitoring technology has been remarkably developed and popularized, and health monitoring equipment capable of monitoring human physiological indexes in real time such as intelligent bracelets and intelligent watches are provided.

However, the existing health monitoring devices are often designed to be used for a long time, are high in price and poor in reusability, and part of the devices are quite heavy and influence convenience and comfort in use, and in addition, the problems of poor data accuracy and reliability and the like exist. In summary, the existing health monitoring devices have some prominent problems in terms of price, reusability, portability, data accuracy, and the like.

Therefore, how to design a convenient, reusable, reliable and accurate health monitoring solution is a problem to be solved at present.

Disclosure of Invention

The purpose of the application is to provide an electronic skin, sweat detection method and sweat detection system, which can meet the requirements of more convenient, economical, reliable and accurate monitoring of user health.

In a first aspect, embodiments of the present application provide an electronic skin comprising: sweat collecting device, sweat detecting device and signal transmission device;

The sweat collecting device is used for collecting sweat on the skin surface of a user;

the sweat detection device comprises a plurality of sweat sensors and a signal processor; each sweat sensor in the plurality of sweat sensors corresponds to a component to be measured reflecting the health condition of the user; each sweat sensor is used for carrying out electrochemical measurement on the component to be detected corresponding to the sweat sensor in sweat and outputting an electric signal; the signal processor is used for processing the electric signals output by the sweat sensors to obtain content information of each component to be detected;

the signal transmission device is used for transmitting the content information of each component to be detected to the external equipment.

In one possible implementation of the first aspect, the electrical signals output by the plurality of sweat sensors include a current signal and a potential signal; the plurality of sweat sensors includes at least one voltammetric electrochemical sensor and at least one potentiometric electrochemical sensor; each voltammetric electrochemical sensor is used for carrying out electrochemical measurement on the component to be measured corresponding to the voltammetric electrochemical sensor in sweat and generating a current signal; each potentiometric electrochemical sensor is used for performing electrochemical measurement on a component to be measured corresponding to the potentiometric electrochemical sensor in sweat and generating a potentiometric signal.

In a possible implementation manner of the first aspect, the at least one voltammetric electrochemical sensor includes at least one of a glucose sensor, a lactate sensor, an ascorbic acid sensor, a uric acid sensor, an ethanol sensor, or an amino acid sensor; the at least one potentiometric electrochemical sensor may include at least one of a sodium ion sensor, a potassium ion sensor, a calcium ion sensor, a chloride ion sensor, or an ammonium ion sensor.

In a possible implementation manner of the first aspect, each sweat sensor in the electronic skin comprises an electrochemical electrode, a sensor interface and a horseshoe-shaped wire connecting the electrochemical electrode and the sensor interface, the sensor interface being connected with the signal processor.

In a possible implementation manner of the first aspect, the sweat collecting device of the electronic skin includes a micro-channel structure corresponding to the sweat sensor one by one, and the micro-channel structure includes at least one sweat absorbing port, an electrode cavity, a flow channel and a sweat outlet port; the sweat absorbing port is used for absorbing sweat on the skin surface of a user, the electrode cavity is used for storing the electrochemical electrode, the runner is used for guiding the sweat absorbed by the sweat absorbing port into the electrode cavity, and the sweat outlet is used for discharging the sweat in the electrode cavity.

In a possible implementation manner of the first aspect, the signal transmission device of the electronic skin includes a magnetic coil, and the magnetic coil is used for wirelessly transmitting content information of the component to be measured.

In a possible implementation manner of the first aspect, the magnetic coil is further configured to receive electric energy sent by a charging coil of an external charging device, where the electric energy is used for supplying the electronic skin, and the method further includes:

in a possible implementation manner of the first aspect, the electronic skin further comprises a safety control device for monitoring whether an electrical signal in the electronic skin is overloaded; and automatically disconnecting the power supply to the electronic skin when an overload is detected.

In a second aspect, embodiments of the present application provide a sweat detection method comprising:

collecting sweat from the surface of the user's skin with a sweat collection device;

electrochemical measurement is carried out on components to be measured, which reflect the health condition of a user, in sweat by utilizing a plurality of sweat sensors, and an electric signal is output;

processing the electric signals output by the sweat sensors by using a signal processor to obtain content information of various components to be detected;

and sending the content information of the various components to be detected to external equipment by using a signal transmission device.

The external equipment is used for receiving and processing the content information of various components to be detected to generate health indexes.

In a third aspect, an embodiment of the present application provides a sweat detection system, where the system includes an electronic skin and an external device, where the electronic skin is any one of the electronic skins described in the first aspect, and the external device is configured to receive content information of various components to be detected in sweat sent by the electronic skin, and process the content information of the various components to be detected to generate a health indicator.

In a fourth aspect, embodiments of the present application provide a computer device comprising a memory, a processor, and a computer program stored in the memory and executable on the processor, which when executed by the processor causes the computer device to implement any one of the implementations of the first and second aspects described above.

In a fifth aspect, embodiments of the present application provide a computer readable storage medium storing a computer program, which when executed by a computer device implements any one of the implementations of the first and second aspects described above.

In a sixth aspect, embodiments of the present application provide a computer program product for, when run on a computer device, causing the computer device to perform the implementation of any of the preceding aspects.

Compared with the prior art, the embodiment of the application has the beneficial effects that:

the application provides an electronic skin of detectable analysis user sweat composition, this electronic skin embeds multiple sweat sensor, can collect the sweat that obtains and detect analysis, processing obtain sweat composition and content information to transmit the testing result to external terminal, through the real-time detection and the control of sweat composition reflect human inside physiological activity and metabolism situation, and then realize the monitoring to user health condition.

Drawings

Fig. 1 is an application scenario diagram of electronic skin according to an embodiment of the present application.

Fig. 2 is a schematic structural diagram of an electronic skin according to an embodiment of the present application.

Fig. 3 is a schematic structural diagram of an electrochemical electrode according to an embodiment of the present application.

Fig. 4 is a schematic structural diagram of a micro flow channel according to another embodiment of the present application.

Fig. 5 is a schematic structural diagram of a sweat sensor according to another embodiment of the present application.

Fig. 6 is a schematic structural diagram of a signal processor according to another embodiment of the present application.

Fig. 7 is a schematic structural diagram of a signal transmission device according to an embodiment of the present application.

Fig. 8 is a schematic structural diagram of a sweat detection system according to an embodiment of the present disclosure.

Fig. 9 is a flow chart of a sweat detection method according to an embodiment of the present application.

Detailed Description

In order to make the objects, technical solutions and advantages of the present application more apparent, the present application will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.

Sweat is an excreta of metabolites in the body, which contains a variety of substances including moisture, electrolytes, metabolites, etc. The content and proportion of these ingredients can be affected by a variety of factors, such as exercise, nutritional status, endocrine regulation, and the like. The change of sweat components can reflect the physiological activities and metabolic conditions in the human body, and further reflect the health conditions of the human body. Therefore, through analysis of sweat components, information about health conditions can be obtained, and the sweat components have certain reference values for health management and disease prevention.

Fig. 1 is a schematic diagram of an application scenario of electronic skin according to an embodiment of the present application.

As shown in fig. 1, the scene includes an electronic skin 100 and a terminal 200 attached to a skin surface of a user. The electronic skin 100 may be in communication with a terminal 200.

In the embodiment of the present application, the electronic skin 100 is a detection device that combines a flexible electronic technology and a sensor technology, and can be attached to the surface of human skin, and various components reflecting the health condition of the human body and their contents in the sweat are analyzed by collecting and detecting the sweat secreted by the human skin.

The terminal 200 may receive sweat composition and content information transmitted from the electronic skin for deep analysis or storage. The terminal 200 may be, for example, an intelligent terminal, a cloud server, etc., and the application does not limit the type of the terminal 200.

In summary, the present application utilizes the electronic skin 100 to collect and detect and analyze sweat components of a user, and transmits the detected sweat components to an external terminal, and reflects physiological activities and metabolic conditions inside a human body through real-time detection and monitoring of the sweat components, thereby realizing monitoring of health conditions of the user.

Fig. 2 is a schematic structural diagram of an electronic skin 100 according to an embodiment of the present application.

One possible configuration of the electronic skin 100 is described below in conjunction with fig. 2.

The electronic skin 100 may include a sweat collecting device 10, a sweat detecting device 20, and a signal transmitting device 30.

The sweat collecting device 10 is used for collecting sweat from the surface of the skin of a user. The sweat collecting device 10 may be arranged, for example, on the side of the electronic skin 100 that is in contact with the human skin.

The sweat detecting device 20 is used for detecting, processing and analyzing sweat collected by the sweat collecting device 10. The sweat detection device 20 may include a plurality of sweat sensors 21 and a signal processor 22. The sweat sensor 21 is used for performing electrochemical measurement on certain components to be measured in sweat, which can reflect the health condition of a user, and outputting an electric signal.

It should be understood that, in the electronic skin 100 of the present application, a plurality of sweat sensors 21 are provided, and each sweat sensor 21 detects a component to be detected in sweat, but the structure and function of the sweat sensor 21 are not limited in the present application, for example, the sweat sensor 21 may be an integrated sensor, and may be used to detect multiple components to be detected, which is not repeated in this application. The signal processor 22 is used for processing and analyzing the electric signals output by the sweat sensor 21 to obtain content information of each component to be detected in sweat.

Sweat sensor 21 is electrically connected to signal processor 22.

The signal transmission device 30 is used for transmitting the content information of each component to be measured in the sweat analyzed by the signal processor 22 to an external device, that is, to the terminal 200.

In this embodiment, an electronic skin 100 for determining health status of a human body by detecting sweat is provided, wherein a sweat collecting device 10, a sweat detecting device 20 and a signal transmitting device 30 are sequentially connected, so as to implement the processes of sweat collection, detection and result transmission.

The heart rate sensor, the blood pressure sensor and the blood oxygen saturation sensor which are arranged by the traditional health monitoring equipment mostly adopt optical sensing or pressure sensing and other technologies. The sweat sensor 21 in the present application is an electrochemical sensor, i.e. an electrode material with specific reactivity or selectivity is used to detect various components to be detected and concentrations in sweat by electrochemical measurement.

Alternatively, the sweat sensor 21 may be classified into a voltammetric electrochemical sensor and a potentiometric electrochemical sensor according to the detection principle. That is, the plurality of sweat sensors 21 may include at least one voltammetric electrochemical sensor and at least one potentiometric electrochemical sensor.

The electrochemical sensor can detect metabolites and electrolytes in human sweat. The voltammetric electrochemical sensor is used for carrying out electrochemical measurement on metabolites in human sweat to generate a current signal. Potentiometric electrochemical sensors are used to electrochemically measure electrolytes in human sweat to produce a potentiometric signal. That is, the electrical signal generated by the sweat sensor 21 can be classified into two types of current signal and potential signal according to the different types thereof.

The specific types and reasons for selection of the various sweat sensors 21 described above are described below in connection with the principles and table 1.

TABLE 1

Among the numerous sweat components, metabolites such as glucose, lactic acid, ascorbic acid, and urea, and electrolytes such as sodium, potassium, calcium, chloride ion, have been selected as target analytes for sweat sensors.

The above components can effectively reflect the health condition of human body.

Glucose in sweat comes from blood sugar, has correlation, and diabetes is related to blood sugar metabolism, so that a new thought is provided for noninvasively detecting diabetes, the glucose content in sweat is low, and a glucose sensor with higher sensitivity is needed.

The concentration of lactic acid can detect stress limit, prevent muscle spasm and ischemia, provide anaerobic exercise physical state evaluation information, and is a common method for clinically measuring hypoxia and lactic acidosis. In addition, the lactic acid content is related to psychological stress, and acute heart diseases such as myocardial ischemia and the like are caused when the lactic acid content is severe, wherein the lactic acid content in sweat is tens times of the glucose content, and the sensor is required to have a large linear range.

Ascorbic acid is a term for vitamin C, which has an anti-scurvy effect. The long-term vitamin C deficiency of human body can cause the occurrence of many disease symptoms, such as listlessness, debilitation, mental depression, weakness, anorexia, gum swelling, hemorrhage, skin hemorrhage, submucosal hemorrhage, etc.

Uric acid can cause various diseases such as gout, urinary calculus, nephropathy and the like. Patients with high uric acid, if not actively treated, may cause gout manifestations as the condition progresses, resulting in pain at the joint. And the urinary calculus and other diseases of patients can also be caused along with the disease development. Secondly, some patients have a certain influence on kidneys due to long-term increase of uric acid in bodies, so that uric acid nephropathy is triggered to cause renal function reduction.

The harm of ethanol to human body mainly comprises the influence on nervous system, digestive system, liver, cardiovascular and cerebrovascular, sperm quality and various systems of the whole body.

The decrease in liver function also leads to an increase in blood ammonia, which results in an increase in ammonia concentration because ammonia metabolism is mainly produced in the liver and urine is excreted via the kidneys, and ammonia is currently unable to form urine. The elevation of blood ammonia is likely to cause hepatic encephalopathy, and therefore, artificial liver is required to reduce blood ammonia.

The amino acid is mainly used for treating diseases of respiratory tract, liver diseases, diseases of digestive tract system and cardiovascular and cerebrovascular diseases, is a necessary nutrient element for human body, can help to supplement nutrition for critical patients, and has the requirement of limiting amino acid intake.

The monitoring of ions is beneficial to the balance of electrolyte in sweat, and the concentration of sodium ions, potassium ions and chloride ions in sweat is higher than that of other ions, so that the method can be used for preventing diseases such as dehydration, muscle spasm, hyponatremia, hypokalemia and cystic fibrosis, and monitoring the physical state of staff in extreme environments. In addition, higher sodium ion concentration can cause increased vascular capacity, resulting in hypertension and increased risk of coronary heart disease and cerebral apoplexy. Calcium ion is related to skeletal development, and can be used for preventing diseases such as kidney stones, myeloma, liver cirrhosis, acid-base imbalance and the like, and the obvious change of the concentration of the calcium ion can cause the disorder of organs and systems of human bodies.

Based on the above-discussed capability of each component to reflect human health, the voltammetric electrochemical sensor in the present application may include a glucose sensor, a lactate sensor, an ascorbic acid sensor, a uric acid sensor, an ethanol sensor, an amino acid sensor, and the potentiometric electrochemical sensor may include a sodium ion, a potassium ion, a calcium ion, a chloride ion, and an ammonium ion sensor.

The detection principle and the structural characteristics of the above-mentioned various sensors are as follows.

The glucose sensor utilizes a new nano material, the existence of the new nano material on the surface of the electrode shortens the distance between the new nano material and the active center of the enzyme protein, and the electron transfer directly occurs on the surface of the electrode, and the new material comprises graphene, carbon nano tubes, nano metal particles and the like.

The active center of lactate oxidase in lactate sensor is in direct contact with the electrode. The direct electron transfer can improve the electron transfer speed, reduce the working potential and improve the anti-interference performance of the sensor, and the development of the sensor depends on the development of nano technology.

When the ascorbic acid sensor, the uric acid sensor, the ethanol sensor and the amino acid sensor respectively carry out electrochemical detection on ascorbic acid, uric acid, ethanol and amino acid, oxidation reaction or reduction reaction can occur, namely the electrochemical reaction is a process of electron migration, faradaic current can be formed in the process, a certain relation exists between the peak value of the current and the concentration of a solution, and quantitative determination on a target object is realized according to the principle in practical application.

The sodium ion sensor, the potassium ion sensor, the calcium ion sensor, the chloride ion sensor and the ammonium ion sensor are voltage response electrochemical sensors, an ion selective electrode is adopted, specific active substances are ion carriers in ion selective films, a working electrode of the ion selective sensor is placed in a liquid to be detected, the ion selective carriers only transport ions to be detected to cross the surface of the films, other ions are isolated outside the films, and the process leads to difference of charges at two ends of the films, so that film potential is generated.

In one embodiment, sweat sensor 21 in the present application may comprise 11 electrochemical sensors, divided into 6 three-electrode voltammetric electrochemical sensors for detecting metabolites in sweat, 5 two-electrode potentiometric electrochemical sensors for detecting electrolytes in sweat.

The electrode structures of the three-electrode voltammetry electrochemical sensor and the two-electrode potentiometric electrochemical sensor are shown in fig. 3.

The sensors of glucose, lactic acid, ascorbic acid, uric acid, ethanol, amino acid and the like are three-electrode electrochemical sensors, and are designed into a circular electrode structure so as to reduce the volume of sweat; the counter electrode area is larger than the working electrode, which results in a smaller current density of the counter electrode, preventing polarization of the counter electrode.

Sodium, potassium, calcium, chloride and ammonium ion sensors the changes in the content of the main ionic components in sweat were tested, solid state ion selective sensors were designed in which the reference electrode needed modification to prevent drift. To reduce the amount of sweat required, a circular electrode structure is also designed.

The sensor for monitoring the various components in the sweat is integrated into the electronic skin, so that a more comprehensive, accurate and personalized health monitoring service is provided for a user. Through monitoring multiple indexes such as uric acid, glucose and electrolyte in real time, a user can comprehensively understand physiological states of the user, including information on metabolic level, nutritional status, electrolyte balance and the like. In terms of disease prevention and management, through these monitoring data, the user can prevent some common diseases such as diabetes, gout caused by high uric acid, and the like. Meanwhile, for patients already suffering from related diseases, some monitoring data may be focused. In addition, sweat monitoring provides a more comfortable and convenient experience relative to traditional blood or urine sampling. Most importantly, this technology will greatly raise the health consciousness of users, let them participate in health management more actively, and integrate health into aspects of daily life. This comprehensive health monitoring service will have a positive promoting effect on the health status of the individual.

Next, each device in the electronic skin 100 will be described in detail with reference to fig. 4 to 7.

Fig. 4 is a schematic structural view of a sweat collecting device 10 according to an embodiment of the present disclosure.

The sweat collecting device 10 adopts a self-driven collecting micro-channel structure.

The self-driven collecting micro-channel is a micro-channel system designed by utilizing the micro-fluid theory, and can realize automatic collection and transportation of samples without external force driving. Typically, the microchannel system utilizes physical properties such as surface tension, capillary action, etc., to allow the sample to flow automatically within the microchannel without the need for an external pump or electric force to push the movement of the sample.

As shown in fig. 4, the micro flow channel includes a sweat absorbing port 11, an electrode cavity 12, a flow channel 13, and a sweat discharging port 14. The sweat absorbing port 11 is used for absorbing sweat on the skin surface of the user. The electrode cavity 12 is used to house the electrochemical electrodes of the sweat sensor 21. The flow channel 13 is communicated with the sweat absorbing port 11 and the electrode cavity 12 and is used for guiding sweat absorbed by the sweat absorbing port 11 into the electrode cavity 12 so that an electrochemical electrode in the electrode cavity 12 detects components to be detected in the sweat. A perspiration port 14 is connected to the electrode lumen 12 for draining perspiration from the electrode lumen 12.

Alternatively, one micro flow channel structure may include a plurality of sweat absorbing ports 11, and sweat absorbed by the plurality of sweat absorbing ports 11 is introduced into the same electrode cavity 12. This configuration can effectively enhance the efficiency of sweat collection, thereby providing a sufficient sample for detection by sweat sensor 21.

Alternatively, the material of the micro flow channel can be PDMS (polydimethylsiloxane), which is easy to reverse, and has the characteristics of biocompatibility, softness and stretchability.

The micro-channel is tightly combined with the skin, sweat is pushed into the sweat absorbing port 11 by sweat gland and capillary action, reaches the electrochemical electrode in the electrode cavity 12 along the channel 13, and finally flows out through the sweat outlet 14, and the micro-channel is required to be tightly attached to the skin. The addition of the micro-flow channel fixes the sweat volume, provides an ideal detection environment, and facilitates the calibration of the sweat sensor.

Fig. 5 is a schematic structural diagram of the sweat sensor 21 in the sweat detecting device 20 according to the embodiment of the present application.

As shown in fig. 5, each sweat sensor 21 may include an electrochemical electrode 211, a sensor interface 212, and a horseshoe-shaped wire 213 connecting the electrochemical electrode 211 and the sensor interface 212.

The sensor in the application adopts flexible extensible design, and the peripheral lead wire of the sensor adopts horseshoe-shaped wire design, so that the sensor has good stretching characteristics, and the integral extensible function of the sensor is realized. In addition, the horseshoe-shaped wires are arranged in a net shape, if one of the wires is broken, the conductive connection can be realized through other wires, so that the stability of the sensor is enhanced. The sensor interface is connected in a flat cable mode, but the flexible flat cable is poor in connection stability with the rigid PCB, so that conductive connection can be realized by using conductive magnetic particles.

The electrochemical electrode 211 may have an electrode structure in the three-electrode voltammetry electrochemical sensor or the two-electrode potentiometric electrochemical sensor of fig. 3.

Fig. 6 is a schematic structural diagram of the signal processor 22 in the sweat detecting device 20 according to the embodiment of the present application.

As shown in fig. 6, the signal processor 22 may include a signal processing module 221 and a data processing module 222.

Optionally, the signal processing module 221 may include an amplifier 223 and an analog-to-digital converter 224. The amplifier 223 may amplify the weak current or potential signal output by the sweat sensor 21 to improve the strength and stability of the signal. Analog-to-digital converter 224 may convert the analog current or potential signal to a digital signal for subsequent digital signal processing and transmission.

Optionally, the data processing module 222 may include a data decoding and recovery unit 225 and a data store 226. The data decoding and recovering unit 225 is configured to decode and recover the transmitted data, and restore the decoded data to the original physiological index data. The data storage 226 is used to temporarily or permanently store processed data, such as flash memory or memory chips.

Fig. 7 is a schematic structural diagram of a signal transmission device 30 according to an embodiment of the present application.

As shown in fig. 7, the signal transmission device 30 may include a magnetic coil 31 and a communication chip 32.

Alternatively, the magnetic coil 31 of the present application may be used for wireless transmission and wireless charging.

When the magnetic coil 31 is used as a communication module, wireless data transmission and reception are realized by using the magnetic coil 31, for example, sweat components to be measured and content information thereof are transmitted to an external device.

When the magnetic coil 31 is used as a power supply module, the magnetic coil 31 is an induction coil, and can receive electric energy sent by a charging coil of an external charging device, and the electric energy is used for charging a power supply of the electronic skin. With this design, the external charging device generates an alternating electromagnetic field, and the magnetic coil 31 in the electronic skin receives this electromagnetic field and generates an induced current. This induced current can be used to power modules and devices in the electronic skin. The wireless power supply mode can avoid the constraint brought by the traditional wired connection, and provides more convenient and flexible use experience. It is noted that the inductive coil power supply requires a certain distance between the electronic skin and the external device and requires good electromagnetic coupling between the two. Furthermore, the efficiency of the induction coil power supply may be affected by factors such as distance, electromagnetic field strength, and relative position. Thus, in designing an induction coil power supply system, proper power matching and position adjustment are required to ensure stable and efficient energy transfer. In summary, the induction coil may be used as a means of wireless power supply to transfer energy from an external device into the electronic skin.

Optionally, the communication chip 32 uses bluetooth, wi-Fi or other communication protocols to control the encoding, transmission and decoding processes of the data to enable communication with external devices.

In one embodiment, a temperature sensor for measuring the temperature of the human body may also be provided in the electronic skin 100 of the present application. The temperature sensor may be integrated within the sweat sensor 21 or may be independent of the sweat sensor 21.

It should be noted that, when the temperature sensor is integrated into the sweat sensor 21, the functions that can be achieved by the sweat sensor 21 are not limited to detecting the component to be detected in sweat, but also include measuring the temperature of the human body. An embodiment in which a temperature sensor is integrated in the sweat sensor 21 is given in fig. 8 below, to describe the whole solution in this case.

Fig. 8 is a schematic structural diagram of a sweat detection system according to an embodiment of the present application.

As shown in fig. 8, the sweat detection system includes an electronic skin 100, a terminal 200, and an external power supply device 300.

It should be appreciated that the electronic skin 100 in the present embodiment may be regarded as one example of the electronic skin 100 in fig. 2.

In the present embodiment, the electronic skin 100 includes the sweat collecting device 10, the sweat detecting device 20, and the signal transmitting device 30, and the three devices are connected in sequence.

Wherein the sweat detection means 20 comprises a sweat sensor 21 and a signal processor 22.

In this embodiment, sweat sensor 21 is an integrated module of multiple sensors, wherein temperature sensor 21-1, voltammetric electrochemical sensor 21-2, and potentiometric electrochemical sensor 21-3.

The voltammetric electrochemical sensor comprises a glucose sensor a, a lactic acid sensor b, an ascorbic acid sensor c, a uric acid sensor d, an ethanol sensor e, an amino acid sensor f and a plurality of sub-sensors. The sensors can detect the content of various metabolites such as glucose, lactic acid, ascorbic acid, uric acid, ethanol, amino acid and the like in sweat so as to monitor in real time.

Similarly, the electrochemical sensor by the potentiometric method comprises a sodium ion sensor g, a potassium ion sensor h, a calcium ion sensor i, a chloride ion sensor j, an ammonium ion sensor k and a plurality of sub-sensors. The sensors can monitor the content of various electrolytes such as sodium ions, potassium ions, calcium ions, chloride ions, ammonium ions and the like in sweat so as to monitor in real time.

The sweat sensor 21 electrochemically detects the skin temperature of the human body and sweat collected by the sweat collecting device 10, and then generates a relevant electric signal, and outputs the electric signal to the signal processor 22.

The signal processor 22 includes a signal processing module 221 and a data processing module 222.

The electrical signals output by the sweat sensor 21 described above are received and processed by the signal processing module 221.

The signal processing module 221 includes an amplifier 223 and an analog-to-digital converter 224. The amplifier 223 may amplify the weak current or potential signal output by the sweat sensor 21 to improve the strength and stability of the signal. Analog-to-digital converter 224 may convert the analog current or potential signal to a digital signal for subsequent digital processing and transmission.

The generated digital signal is output after the operations such as amplification, analog-to-digital conversion, etc. are performed on the electrical signal by the signal processing module 221. The digital signal is further processed by a data processing module 222.

The data processing module 222 may include a data decoding and recovery unit 225 and a data store 226.

The digital signal is processed and analyzed by the data processing module 222 to obtain information such as the content of the components to be measured of body temperature and sweat. The data storage 226 is used to temporarily or permanently store processed data, such as flash memory or memory chips.

The sweat component content data and the body temperature data which are processed by the data processing module are transmitted to the terminal 200 by the signal transmission device 30.

The signal transmission device 30 includes a magnetic coil 31 and a communication chip 32.

The magnetic coil 31 may be used for wireless transmission and wireless charging.

When the magnetic coil 31 is used as a power supply module, the magnetic coil 31 is an induction coil, and can receive electric energy sent by a charging coil of an external charging device, and the electric energy is used for charging a power supply of the electronic skin.

The communication chip 32 uses bluetooth, wi-Fi or other communication protocols to control the encoding, transmission and decoding processes of data to enable communication with external devices.

After receiving the data sent by the electronic skin 100, the terminal 200 may process and analyze the data to generate a health indicator. The user may monitor the physical condition based on the health indicator.

Optionally, when the terminal 200 determines that the content of the component to be measured exceeds the preset threshold, an alarm is sent to alert the user to pay attention to the self situation, and take remedial measures in time, such as injecting insulin or seeking medical care in time.

The embodiment of the application further comprises an external power supply device 300, which can perform induction power transmission with the magnetic coil 31. Thus, the external power supply device 300 also has an induction coil for wireless power supply, which may be, for example, a wireless charger, the type of which is not limited in the present application.

In conclusion, the sweat detection system of the embodiment of the application is composed of the structure, and the sweat detection system can be used for detecting and analyzing key components in human sweat so as to achieve the purpose of monitoring the health condition of a user in real time.

In one embodiment, the electronic skin 100 may also include a temperature sensor.

The temperature sensor for measuring body temperature may be integrated within sweat detection device 20 and coupled to signal processor 22.

Optionally, a patch temperature sensor is selected and directly mounted on the surface of the circuit board in a patch manner. The principle of a patch temperature sensor is generally based on the working principle of a thermistor. The main component of the patch temperature sensor is a thermistor element, typically a thermistor chip. The resistance value of the thermistor chip varies with temperature, and Negative Temperature Coefficient (NTC) thermistors are commonly used. When the patch temperature sensor is exposed to the temperature environment to be measured, the temperature of the thermistor chip also changes correspondingly. According to the characteristics of the thermistor, the resistance value and the temperature are in negative correlation, namely, the resistance value is reduced when the temperature is increased, and the resistance value is increased when the temperature is reduced. In order to measure the temperature, the patch temperature sensor is typically connected to a measurement circuit in the circuit, and the measurement circuit passes a current through the patch temperature sensor to measure a voltage or current signal generated by the resistor, so as to calculate the temperature according to the resistance change of the thermistor.

Specifically, the temperature calculation process may be performed by the signal processor 22.

In one embodiment, the electronic skin 100 may also include a safety control device.

A safety control device may be connected to the electrical circuitry in the electronic skin 100 for monitoring whether an electrical signal in the electronic skin 100 is overloaded. When an overload of the current or voltage in the circuit is detected, the power supply of the electronic skin 100 is automatically turned off to protect the safety of the user.

In one embodiment, the electronic skin 100 may also include a display device.

The screen display device can comprise a display screen, and sweat components and content information obtained through processing and analysis can be displayed to a user through the built-in screen display device.

In one embodiment, the electronic skin 100 may also include a power generation device.

The power generation device may utilize ions in sweat to generate electrical energy to power the electronic skin 100.

It should be noted that the electronic skin 100 in the present application has soft and stretchable properties, and thus can be worn on the skin surface of the user in a conformable manner. To achieve this feature, the electronic skin 100 uses a flexible substrate, i.e., a soft, breathable material such as a polymer or elastic film, to ensure the fit and comfort of the electronic skin to the skin; in addition, the electronic skin 100 employs a flexible housing/patch material, i.e., a soft, breathable material that protects the interior modules and sensors and enables them to adhere securely to the skin, such as the sweat collecting device 10 employing a soft stretchable microchannel structure, and such as the sweat sensor 21 also employing a flexible PDMS material as a substrate.

The present application gives a reliable and accurate health monitoring solution by providing such a disposable low cost non-invasive health monitoring electronic skin.

The electronic skin in the application is used as a soft and wearable device, can be attached to the surface of a human body and can monitor various physiological indexes in real time. The disposable design eliminates the trouble of multiplexing, and the user only needs to use once without periodic replacement or maintenance.

The electronic skin in the application adopts a sensing technology and an algorithm, and can monitor health indexes such as glucose, lactic acid and the like in real time. Through transmitting the data to the smart phone or the cloud for analysis and recording, the user can easily track and manage the health condition of the user. Due to the low cost and convenience, more users can enjoy high-quality health monitoring service, and the improvement of the overall health level is promoted.

It should be appreciated that the sweat detection method of fig. 9 is implemented by the sweat detection system of fig. 8, the main implementation subject of which is the electronic skin 100 in the present application.

As shown in fig. 9, the sweat detection method may include the following steps.

S1, collecting sweat on the skin surface of a user by utilizing a sweat collecting device.

S2, electrochemical measurement is carried out on components to be detected, which reflect the health condition of a user, in sweat by utilizing a plurality of sweat sensors, and electric signals are output.

S3, processing the electric signals output by the sweat sensors by using a signal processor to obtain content information of various components to be detected.

And S4, transmitting content information of various components to be detected to external equipment by utilizing a signal transmission device.

The external equipment can analyze the content information of the components to be detected, and when judging that the content of the components to be detected exceeds a preset threshold value, the external equipment sends out alarm information.

In one embodiment, the sweat detection method in fig. 9 may include the following steps.

(1) The electronic skin is prepared. I.e. a piece of electronic skin is removed, ensuring its integrity and no damage.

(2) An appropriate location is selected. I.e. selecting a position suitable for attachment to the electronic skin, for example, the wrist, forearm, chest etc. can be selected for ease of monitoring.

(3) The skin surface is prepared. I.e. cleaning and drying the skin surface at the attachment site, ensuring that there is no grease, dirt or perspiration.

(4) Attaching electronic skin. The back of the electronic skin is attached to the clean skin surface, and the electronic skin is tightly attached to the skin and is not easy to fall off by lightly pressing.

(5) The electronic skin is activated. I.e. by means of self-starting or manual starting.

(6) The process is monitored. That is, once the electronic skin is activated, the sensor module begins to collect physiological index data, such as chemical concentration, ion concentration, etc. in sweat.

(7) Data processing and analysis. I.e. the data processing module of the electronic skin receives and processes the data collected by the sensor. The data is processed, analyzed, and interpreted using specific algorithms and models, from which critical health indicators, such as blood glucose levels, ion balance, etc., are extracted.

(8) Data presentation and communication. I.e. the processed data can be presented to the user via a display screen built in the electronic skin. Meanwhile, the communication module of the electronic skin can transmit data to external equipment, such as a smart phone or a computer, in a wireless manner, so that a user can analyze, store or share the data in more detail.

(9) The electronic skin is removed. I.e. when the user needs to remove the electronic skin, he can peel it from the skin surface following the instructions for proper treatment and disposal.

The above procedure illustrates the overall process of sweat detection using electronic skin 100, through which a user may conveniently use electronic skin for health monitoring. The whole process is simple and easy to implement, a user only needs to attach the electronic skin at a proper position and start the electronic skin, and then the electronic skin can automatically start to monitor physiological indexes and generate electricity. The processing and analysis of the data enables the user to know the health condition of the user and to communicate data with the external device through the communication function. The simplicity and convenience of the user experience process makes the electronic skin a convenient health monitoring tool.

It should be understood that, although the steps in the flowcharts are shown in order in the above-described embodiments, the steps are not necessarily performed in the order shown in the drawings. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least some of the steps in the flowcharts described in the above embodiments may include a plurality of steps or a plurality of stages, which are not necessarily performed at the same time, but may be performed at different times, and the order of the steps or stages is not necessarily performed sequentially, but may be performed alternately or alternately with at least some of the other steps or stages.

It will be apparent to those skilled in the art that, for convenience and brevity of description, only the above-described division of the functional units and modules is illustrated, and in practical application, the above-described functional distribution may be performed by different functional units and modules according to needs, i.e. the internal structure of the apparatus is divided into different functional units or modules to perform all or part of the above-described functions. The functional units and modules in the embodiment may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit, where the integrated units may be implemented in a form of hardware or a form of a software functional unit. In addition, specific names of the functional units and modules are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present application. The specific working process of the units and modules in the above system may refer to the corresponding process in the foregoing method embodiment, which is not described herein again.

The embodiment of the application also provides a computer device, which comprises: at least one processor, a memory, and a computer program stored in the memory and executable on the at least one processor, which when executed by the processor performs the steps of any of the various method embodiments described above.

Embodiments of the present application also provide a computer readable storage medium storing a computer program which, when executed by a processor, implements steps that may implement the various method embodiments described above.

Embodiments of the present application provide a computer program product which, when run on a mobile terminal, causes the mobile terminal to perform steps that may be performed in the various method embodiments described above.

In the foregoing embodiments, the descriptions of the embodiments are emphasized, and in part, not described or illustrated in any particular embodiment, reference is made to the related descriptions of other embodiments.

Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.

In the embodiments provided in the present application, it should be understood that the disclosed apparatus/terminal device and method may be implemented in other manners. For example, the apparatus/terminal device embodiments described above are merely illustrative, e.g., the division of the modules or units is merely a logical function division, and there may be additional divisions in actual implementation, e.g., multiple units or components may be combined or integrated into another system, or some features may be omitted or not performed. Alternatively, the coupling or direct coupling or communication connection shown or discussed may be an indirect coupling or communication connection via interfaces, devices or units, which may be in electrical, mechanical or other forms.

The units described as separate units may or may not be physically separate, and units shown as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

In addition, each functional unit in each embodiment of the present application may be integrated in one processing unit, or each unit may exist alone physically, or two or more units may be integrated in one unit. The integrated units may be implemented in hardware or in software functional units.

The integrated modules/units, if implemented in the form of software functional units and sold or used as stand-alone products, may be stored in a computer readable storage medium. Based on such understanding, the present application may implement all or part of the flow of the method of the above embodiment, or may be implemented by a computer program to instruct related hardware, where the computer program may be stored in a computer readable storage medium, and when the computer program is executed by a processor, the computer program may implement the steps of each method embodiment described above. Wherein the computer program comprises computer program code which may be in source code form, object code form, executable file or some intermediate form etc. The computer readable medium may include: any entity or device capable of carrying the computer program code, a recording medium, a U disk, a removable hard disk, a magnetic disk, an optical disk, a computer Memory, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), an electrical carrier signal, a telecommunications signal, a software distribution medium, and so forth. It should be noted that the computer readable medium contains content that can be appropriately scaled according to the requirements of jurisdictions in which such content is subject to legislation and patent practice, such as in certain jurisdictions in which such content is subject to legislation and patent practice, the computer readable medium does not include electrical carrier signals and telecommunication signals.

The above embodiments are only for illustrating the technical solution of the present application, and are not limiting; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present application, and are intended to be included in the scope of the present application.

In the description above, for purposes of explanation and not limitation, specific details are set forth, such as particular system configurations, techniques, etc. in order to provide a thorough understanding of the embodiments of the present application. It will be apparent, however, to one skilled in the art that the present application may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present application with unnecessary detail.

It should be understood that the terms "comprises" and/or "comprising," when used in this specification and the appended claims, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.

It should also be understood that the term "and/or" as used in this specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.

In the embodiments of the present application, "at least one" means one or more, and "a plurality" means two or more. "and/or", describes an association relation of association objects, and indicates that there may be three kinds of relations, for example, a and/or B, and may indicate that a alone exists, a and B together, and B alone exists. Wherein A, B may be singular or plural. The character "/" generally indicates that the context-dependent object is an "or" relationship. "at least one of the following" and the like means any combination of these items, including any combination of single or plural items. For example, at least one of a, b and c may represent: a, b, c, a and b, a and c, b and c or a and b and c, wherein a, b and c can be single or multiple.

As used in this specification and the appended claims, the term "if" may be interpreted as "when..once" or "in response to a determination" or "in response to detection" depending on the context. Similarly, the phrase "if a determination" or "if a [ described condition or event ] is detected" may be interpreted in the context of meaning "upon determination" or "in response to determination" or "upon detection of a [ described condition or event ]" or "in response to detection of a [ described condition or event ]".

In addition, in the description of the present application and the appended claims, the terms "first," "second," "third," and the like are used merely to distinguish between descriptions and are not to be construed as indicating or implying relative importance.

Reference in the specification to "one embodiment" or "some embodiments" or the like means that a particular feature, structure, or characteristic described in connection with the embodiment is included in one or more embodiments of the application. Thus, appearances of the phrases "in one embodiment," "in some embodiments," "in other embodiments," and the like in the specification are not necessarily all referring to the same embodiment, but mean "one or more but not all embodiments" unless expressly specified otherwise. The terms "comprising," "including," "having," and variations thereof mean "including but not limited to," unless expressly specified otherwise.

Claims

1. An electronic skin, comprising: sweat collecting device, sweat detecting device and signal transmission device;

The sweat detection device includes a plurality of sweat sensors and a signal processor; each sweat sensor in the plurality of sweat sensors corresponds to a component to be detected reflecting the health condition of a user; each sweat sensor is used for carrying out electrochemical measurement on the component to be detected corresponding to the sweat sensor in sweat and outputting an electric signal; the signal processor is used for processing the electric signals output by the sweat sensors to obtain content information of each component to be detected;

the signal transmission device is used for transmitting the content information of each component to be detected to external equipment.

2. The electronic skin of claim 1, wherein the electrical signals output by the plurality of sweat sensors comprise a current signal and a potential signal; the plurality of sweat sensors includes at least one voltammetric electrochemical sensor and at least one potentiometric electrochemical sensor; each voltammetric electrochemical sensor is used for carrying out electrochemical measurement on the component to be measured corresponding to the voltammetric electrochemical sensor in sweat and generating a current signal; each potentiometric electrochemical sensor is used for performing electrochemical measurement on a component to be measured corresponding to the potentiometric electrochemical sensor in sweat and generating a potentiometric signal.

3. The electronic skin of claim 2, wherein the at least one voltammetric electrochemical sensor comprises at least one of a glucose sensor, a lactate sensor, an ascorbate sensor, a uric acid sensor, an ethanol sensor, or an amino acid sensor; the at least one potentiometric electrochemical sensor includes at least one of a sodium ion sensor, a potassium ion sensor, a calcium ion sensor, a chloride ion sensor, or an ammonium ion sensor.

4. An electronic skin according to any one of claims 1 to 3, wherein each sweat sensor comprises an electrochemical electrode, a sensor interface and a horseshoe wire connecting the electrochemical electrode and the sensor interface, the sensor interface being connected to the signal processor.

5. The electronic skin of claim 4, wherein the sweat collection device comprises a micro-channel structure in one-to-one correspondence with the sweat sensor, the micro-channel structure comprising at least one sweat absorbing port, an electrode cavity, a flow channel, and a sweat outlet port; the sweat absorbing port is used for absorbing sweat on the skin surface of a user, the electrode cavity is used for storing the electrochemical electrode, the flow channel is used for guiding the sweat absorbed by the sweat absorbing port into the electrode cavity, and the sweat outlet is used for discharging the sweat in the electrode cavity.

6. An electronic skin according to any one of claims 1 to 3, characterized in that the signal transmission means comprise a magnetic coil for wireless transmission of content information of the component to be measured.

7. The electronic skin of claim 6, wherein the magnetic coil is further configured to receive power transmitted by a charging coil of an external charging device, the power being configured to charge a power source of the electronic skin.

8. An electronic skin according to any one of claims 1 to 3, characterized in that the electronic skin further comprises:

safety control means for monitoring whether an electrical signal in said electronic skin is overloaded; and automatically disconnecting the power supply to the electronic skin when an overload is detected.

9. A sweat detection method, comprising:

electrochemical measurement is carried out on a plurality of components to be measured, which reflect the health condition of a user, in sweat by utilizing a plurality of sweat sensors, and an electric signal is output;

Transmitting content information of the various components to be detected to external equipment by utilizing a signal transmission device;

the external equipment is used for receiving and processing the content information of the various components to be detected to generate health indexes.

10. A sweat detection system comprising an electronic skin and an external device, wherein the electronic skin is the electronic skin according to any one of claims 1 to 8, and the external device is configured to receive content information of various components to be detected in sweat sent by the electronic skin, and process the content information of the various components to be detected to generate a health indicator.